Mus musculus

38 known processes

Kcnq1

potassium voltage-gated channel, subfamily Q, member 1

(Aliases: AW559127,Kcna9,KVLQT1)

Kcnq1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.998
Human Mouse Rat Worm
regulation of membrane potential GO:0042391 192 0.997
Human Mouse Rat
potassium ion transmembrane transport GO:0071805 43 0.997
Human Mouse Rat Worm
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 16 0.996
inorganic ion transmembrane transport GO:0098660 234 0.994
Human Mouse Rat Worm
inorganic cation transmembrane transport GO:0098662 207 0.992
Human Mouse Rat Worm
sensory perception of mechanical stimulus GO:0050954 107 0.988
Mouse
cation transmembrane transport GO:0098655 266 0.988
Human Mouse Rat Worm
cation transport GO:0006812 399 0.984
Human Mouse Rat Worm
transmembrane transport GO:0055085 412 0.979
Human Mouse Rat Worm
cardiac muscle tissue growth involved in heart morphogenesis GO:0003245 1 0.979
auditory receptor cell differentiation GO:0042491 37 0.969
regulation of renal sodium excretion GO:0035813 3 0.954
detection of mechanical stimulus involved in sensory perception GO:0050974 23 0.954
sensory perception of sound GO:0007605 97 0.937
Mouse
cellular potassium ion transport GO:0071804 43 0.937
Human Mouse Rat Worm
cardiac muscle tissue morphogenesis GO:0055008 44 0.930
striated muscle tissue development GO:0014706 293 0.924
epithelial cell development GO:0002064 159 0.918
neuronal action potential GO:0019228 54 0.892
cellular ion homeostasis GO:0006873 165 0.881
regulation of transmembrane transport GO:0034762 128 0.878
Human Mouse Rat
cation homeostasis GO:0055080 212 0.874
action potential GO:0001508 78 0.874
Human
regulation of cellular amine metabolic process GO:0033238 20 0.873
monovalent inorganic cation homeostasis GO:0055067 33 0.870
sodium ion transport GO:0006814 73 0.859
cardiac muscle tissue development GO:0048738 130 0.858
ventricular cardiac muscle cell action potential GO:0086005 4 0.857
Human
ras protein signal transduction GO:0007265 77 0.853
multicellular organismal signaling GO:0035637 91 0.851
Human Mouse
cellular chemical homeostasis GO:0055082 215 0.849
epidermis development GO:0008544 187 0.848
cellular homeostasis GO:0019725 240 0.840
locomotory behavior GO:0007626 195 0.833
male gamete generation GO:0048232 285 0.833
organophosphate catabolic process GO:0046434 232 0.822
potassium ion transport GO:0006813 52 0.813
Human Mouse Rat Worm
actin filament based movement GO:0030048 23 0.806
regulation of blood pressure GO:0008217 93 0.803
regulation of cellular ketone metabolic process GO:0010565 66 0.803
skin development GO:0043588 220 0.800
detection of mechanical stimulus GO:0050982 27 0.799
inner ear receptor cell differentiation GO:0060113 61 0.798
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.794
anatomical structure homeostasis GO:0060249 145 0.784
ear development GO:0043583 200 0.779
Mouse
vestibular receptor cell development GO:0060118 2 0.766
metal ion homeostasis GO:0055065 189 0.761
circulatory system process GO:0003013 197 0.759
Human
growth involved in heart morphogenesis GO:0003241 4 0.755
renal system development GO:0072001 225 0.740
divalent metal ion transport GO:0070838 172 0.732
tissue homeostasis GO:0001894 115 0.722
cellular amine metabolic process GO:0044106 44 0.713
cardiac muscle cell contraction GO:0086003 7 0.709
purine ribonucleoside metabolic process GO:0046128 241 0.708
ribonucleoside catabolic process GO:0042454 206 0.702
synaptic transmission GO:0007268 329 0.700
sensory perception GO:0007600 245 0.698
Mouse
regulation of metal ion transport GO:0010959 106 0.695
Human
anion transport GO:0006820 177 0.676
sensory organ morphogenesis GO:0090596 242 0.672
Mouse
purine containing compound catabolic process GO:0072523 213 0.672
nucleotide catabolic process GO:0009166 217 0.666
muscle tissue morphogenesis GO:0060415 53 0.660
heart morphogenesis GO:0003007 178 0.660
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.659
transmission of nerve impulse GO:0019226 76 0.657
Mouse
regulation of muscle system process GO:0090257 80 0.656
Human
sphingosine 1 phosphate signaling pathway GO:0003376 3 0.649
positive regulation of cellular amine metabolic process GO:0033240 5 0.623
purine ribonucleoside catabolic process GO:0046130 205 0.616
muscle contraction GO:0006936 101 0.609
Human
regulation of ion transport GO:0043269 215 0.609
Human Mouse Rat
thyroid hormone metabolic process GO:0042403 16 0.603
nephric duct formation GO:0072179 4 0.600
potassium ion homeostasis GO:0055075 4 0.597
organ growth GO:0035265 117 0.592
hair cell differentiation GO:0035315 40 0.589
nucleoside triphosphate catabolic process GO:0009143 205 0.586
gland development GO:0048732 330 0.583
equilibrioception GO:0050957 3 0.570
cellular amino acid metabolic process GO:0006520 103 0.564
inner ear receptor cell development GO:0060119 39 0.558
endodermal cell fate determination GO:0007493 2 0.552
regulation of system process GO:0044057 200 0.550
Human Rat
heterocycle catabolic process GO:0046700 280 0.544
acid secretion GO:0046717 33 0.544
Rat
muscle tissue development GO:0060537 308 0.537
muscle system process GO:0003012 141 0.536
Human
embryonic organ morphogenesis GO:0048562 276 0.534
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.529
excretion GO:0007588 22 0.527
interleukin 5 secretion GO:0072603 2 0.527
carboxylic acid transport GO:0046942 100 0.525
organonitrogen compound catabolic process GO:1901565 264 0.524
multicellular organismal homeostasis GO:0048871 164 0.519
leukocyte mediated immunity GO:0002443 174 0.508
regulation of cell cycle GO:0051726 281 0.497
regulation of cell division GO:0051302 76 0.496
striated muscle contraction GO:0006941 45 0.496
Human
actin cytoskeleton organization GO:0030036 220 0.492
regulation of g protein activated inward rectifier potassium channel activity GO:1900128 1 0.492
nephron development GO:0072006 109 0.491
endothelial cell differentiation GO:0045446 41 0.488
chloride transmembrane transport GO:1902476 24 0.482
nephron tubule development GO:0072080 84 0.481
mechanoreceptor differentiation GO:0042490 67 0.479
organic hydroxy compound transport GO:0015850 93 0.474
renal sodium ion transport GO:0003096 2 0.473
peptide transport GO:0015833 133 0.470
Rat
positive regulation of programmed cell death GO:0043068 218 0.468
regulation of protein localization GO:0032880 231 0.460
retina development in camera type eye GO:0060041 119 0.457
ribonucleotide catabolic process GO:0009261 208 0.456
developmental maturation GO:0021700 193 0.447
negative regulation of cytosolic calcium ion concentration GO:0051481 2 0.442
sodium ion transmembrane transport GO:0035725 49 0.442
regulation of secretion GO:0051046 274 0.435
Rat
metanephric dct cell differentiation GO:0072240 3 0.433
regulation of ion homeostasis GO:2000021 64 0.431
positive regulation of thyroid hormone generation GO:2000611 2 0.431
cellular metal ion homeostasis GO:0006875 151 0.429
ear morphogenesis GO:0042471 118 0.418
Mouse
divalent inorganic cation transport GO:0072511 178 0.415
regulation of inward rectifier potassium channel activity GO:1901979 1 0.414
ribonucleoside monophosphate catabolic process GO:0009158 57 0.411
glycosyl compound catabolic process GO:1901658 206 0.410
regulation of secretion by cell GO:1903530 249 0.407
Rat
adult behavior GO:0030534 135 0.399
glycosyl compound metabolic process GO:1901657 246 0.397
nitrogen compound transport GO:0071705 271 0.394
Rat
regulation of systemic arterial blood pressure by atrial natriuretic peptide GO:0003050 2 0.391
purine nucleoside triphosphate catabolic process GO:0009146 203 0.385
blood circulation GO:0008015 195 0.375
Human
regulation of ion transmembrane transport GO:0034765 119 0.374
Human Mouse Rat
metanephric ascending thin limb development GO:0072218 2 0.372
organic cyclic compound catabolic process GO:1901361 295 0.372
detection of stimulus involved in sensory perception GO:0050906 44 0.370
establishment of endothelial barrier GO:0061028 5 0.363
loop of henle development GO:0072070 10 0.354
nucleobase containing small molecule metabolic process GO:0055086 352 0.352
metanephric epithelium development GO:0072207 21 0.349
heart process GO:0003015 94 0.336
Human
calcium ion transmembrane transport GO:0070588 85 0.335
wnt signaling pathway involved in kidney development GO:0061289 2 0.332
l glutamate import into cell GO:1990123 3 0.332
metanephric nephron tubule formation GO:0072289 4 0.331
phagolysosome assembly GO:0001845 3 0.330
ensheathment of neurons GO:0007272 76 0.328
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.326
regulation of endocytosis GO:0030100 69 0.325
aromatic compound catabolic process GO:0019439 286 0.323
cardiac ventricle development GO:0003231 83 0.321
positive regulation of ion transport GO:0043270 65 0.319
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.318
purine nucleoside metabolic process GO:0042278 241 0.316
regulation of potassium ion transmembrane transporter activity GO:1901016 7 0.314
inner ear morphogenesis GO:0042472 101 0.313
Mouse
forebrain development GO:0030900 302 0.313
cell adhesion GO:0007155 329 0.312
urogenital system development GO:0001655 261 0.312
renal sodium excretion GO:0035812 3 0.310
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.307
cardiac muscle contraction GO:0060048 32 0.306
Human
ribonucleoside metabolic process GO:0009119 245 0.304
biomineral tissue development GO:0031214 64 0.302
dicarboxylic acid transport GO:0006835 29 0.298
regulation of transferase activity GO:0051338 263 0.298
cellular divalent inorganic cation homeostasis GO:0072503 127 0.296
positive regulation of apoptotic process GO:0043065 217 0.293
neurohypophysis development GO:0021985 2 0.293
bone mineralization GO:0030282 54 0.291
calcium ion homeostasis GO:0055074 127 0.290
inorganic anion transmembrane transport GO:0098661 29 0.290
actin filament organization GO:0007015 113 0.290
renal system process GO:0003014 48 0.288
nucleoside catabolic process GO:0009164 206 0.285
purine nucleoside catabolic process GO:0006152 205 0.285
renal vesicle induction GO:0072034 3 0.283
nucleoside metabolic process GO:0009116 246 0.283
phenol containing compound metabolic process GO:0018958 60 0.283
nucleoside triphosphate metabolic process GO:0009141 230 0.282
cell maturation GO:0048469 127 0.281
positive regulation of protein phosphorylation GO:0001934 242 0.276
prostate gland morphogenetic growth GO:0060737 4 0.275
sensory organ boundary specification GO:0008052 1 0.272
nephron epithelium development GO:0072009 92 0.270
purine nucleoside triphosphate metabolic process GO:0009144 226 0.267
ventricular cardiac muscle tissue development GO:0003229 38 0.266
calcium ion transport GO:0006816 159 0.266
pilomotor reflex GO:0097195 3 0.261
defecation GO:0030421 1 0.260
regulation of kinase activity GO:0043549 249 0.257
rho protein signal transduction GO:0007266 32 0.257
ossification GO:0001503 216 0.256
carbohydrate derivative catabolic process GO:1901136 231 0.253
regulation of homeostatic process GO:0032844 182 0.249
regulation of nucleoside metabolic process GO:0009118 130 0.247
digestive system development GO:0055123 200 0.247
axonogenesis GO:0007409 274 0.247
cardiac muscle hypertrophy in response to stress GO:0014898 10 0.247
regulation of epithelial cell proliferation GO:0050678 141 0.245
regulation of ossification GO:0030278 112 0.236
transdifferentiation GO:0060290 1 0.234
regulation of systemic arterial blood pressure GO:0003073 61 0.233
cell division GO:0051301 120 0.232
cell type specific apoptotic process GO:0097285 268 0.231
cardiac ventricle morphogenesis GO:0003208 50 0.228
regulation of neuron differentiation GO:0045664 281 0.228
embryonic epithelial tube formation GO:0001838 130 0.227
protein secretion GO:0009306 111 0.225
regulation of thyroid hormone generation GO:2000609 4 0.223
regulation of nuclear division GO:0051783 56 0.223
neuron projection guidance GO:0097485 141 0.222
organic acid transport GO:0015849 101 0.219
endocytosis GO:0006897 168 0.216
anatomical structure maturation GO:0071695 49 0.215
amine metabolic process GO:0009308 45 0.215
heart trabecula morphogenesis GO:0061384 26 0.214
organic hydroxy compound metabolic process GO:1901615 203 0.214
synapse organization GO:0050808 125 0.214
positive regulation of kinase activity GO:0033674 155 0.212
regulation of resting membrane potential GO:0060075 3 0.211
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.211
catecholamine metabolic process GO:0006584 30 0.208
septum primum development GO:0003284 4 0.208
digestion GO:0007586 40 0.208
Rat
response to lipopolysaccharide GO:0032496 128 0.207
regulation of cell motility GO:2000145 236 0.206
multicellular organism growth GO:0035264 161 0.206
nucleoside phosphate metabolic process GO:0006753 338 0.205
regulation of blood circulation GO:1903522 93 0.205
Human
regulation of ph GO:0006885 26 0.202
purine ribonucleotide metabolic process GO:0009150 290 0.202
exocytosis GO:0006887 121 0.202
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.201
wound healing GO:0042060 157 0.200
regulation of cell cycle process GO:0010564 160 0.200
cerebellum formation GO:0021588 1 0.200
atrial septum primum morphogenesis GO:0003289 3 0.197
response to molecule of bacterial origin GO:0002237 143 0.195
developmental growth involved in morphogenesis GO:0060560 138 0.193
glial cell development GO:0021782 54 0.193
lens epithelial cell proliferation GO:0097166 1 0.192
adult walking behavior GO:0007628 41 0.191
regulation of meiotic cell cycle GO:0051445 34 0.191
glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000701 1 0.190
fat cell differentiation GO:0045444 160 0.189
l amino acid transport GO:0015807 32 0.189
spermatogenesis GO:0007283 284 0.188
regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000702 1 0.187
embryonic limb morphogenesis GO:0030326 126 0.185
hindbrain formation GO:0021576 1 0.185
regulation of cell projection organization GO:0031344 206 0.185
nephron tubule formation GO:0072079 20 0.185
cell fate commitment GO:0045165 210 0.185
cellular nitrogen compound catabolic process GO:0044270 280 0.183
negative regulation of cell fate specification GO:0009996 4 0.183
regulation of ras protein signal transduction GO:0046578 114 0.181
mitotic cell cycle GO:0000278 195 0.181
purine nucleotide metabolic process GO:0006163 302 0.178
camera type eye development GO:0043010 266 0.177
regulation of cardiac muscle cell contraction GO:0086004 11 0.177
Human
amide transport GO:0042886 138 0.176
Rat
hormone metabolic process GO:0042445 86 0.176
guanosine containing compound metabolic process GO:1901068 144 0.175
positive regulation of cell migration GO:0030335 109 0.175
glucose homeostasis GO:0042593 128 0.174
adult locomotory behavior GO:0008344 91 0.173
bone remodeling GO:0046849 53 0.172
divalent inorganic cation homeostasis GO:0072507 138 0.172
lymphocyte differentiation GO:0030098 242 0.171
purine containing compound metabolic process GO:0072521 311 0.170
regulation of peptide transport GO:0090087 91 0.168
Rat
ectodermal cell fate commitment GO:0001712 1 0.167
myelination in peripheral nervous system GO:0022011 19 0.165
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.164
endothelium development GO:0003158 45 0.164
regulation of vesicle mediated transport GO:0060627 139 0.164
hormone secretion GO:0046879 128 0.163
Rat
regulation of bone mineralization GO:0030500 31 0.163
cardiac chamber development GO:0003205 108 0.162
positive regulation of cardioblast differentiation GO:0051891 3 0.162
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.161
regulation of hydrolase activity GO:0051336 246 0.160
ribonucleotide metabolic process GO:0009259 291 0.159
renal tubule development GO:0061326 87 0.155
astrocyte fate commitment GO:0060018 4 0.154
regulation of ion transmembrane transporter activity GO:0032412 54 0.154
activation of mapk activity GO:0000187 59 0.152
striated muscle hypertrophy GO:0014897 24 0.151
negative regulation of cell development GO:0010721 169 0.151
negative regulation of secretion GO:0051048 61 0.150
Rat
sodium ion homeostasis GO:0055078 7 0.148
positive regulation of dipeptide transmembrane transport GO:2001150 2 0.148
muscle cell differentiation GO:0042692 261 0.146
lipid biosynthetic process GO:0008610 179 0.146
developmental programmed cell death GO:0010623 41 0.146
regulation of auditory receptor cell differentiation GO:0045607 4 0.145
neural retina development GO:0003407 41 0.144
regulation of synaptic plasticity GO:0048167 87 0.144
metanephric loop of henle development GO:0072236 4 0.144
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.143
feeding behavior GO:0007631 62 0.140
protein maturation GO:0051604 176 0.140
positive regulation of cell death GO:0010942 224 0.140
cytokine production GO:0001816 319 0.138
leukocyte migration GO:0050900 124 0.138
cellular ketone metabolic process GO:0042180 84 0.137
regulation of leukocyte differentiation GO:1902105 159 0.135
axon ensheathment GO:0008366 76 0.133
lung lobe formation GO:0060464 1 0.132
positive regulation of glycolytic process GO:0045821 4 0.131
synapse assembly GO:0007416 56 0.131
stem cell maintenance GO:0019827 130 0.131
negative regulation of phosphate metabolic process GO:0045936 184 0.131
metencephalon development GO:0022037 89 0.131
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.130
regulation of heart contraction GO:0008016 77 0.129
Human
positive regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014718 2 0.129
astrocyte development GO:0014002 12 0.128
stem cell development GO:0048864 219 0.128
organic anion transport GO:0015711 137 0.127
neuromuscular process controlling balance GO:0050885 59 0.127
organelle fission GO:0048285 170 0.126
regulation of cell proliferation involved in mesonephros development GO:2000606 1 0.126
av node cell to bundle of his cell communication GO:0086067 2 0.126
regulation of rho protein signal transduction GO:0035023 71 0.124
positive regulation of growth GO:0045927 104 0.123
lateral inhibition GO:0046331 1 0.123
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.123
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.123
cell recognition GO:0008037 83 0.123
regulation of endothelial cell differentiation GO:0045601 10 0.121
lymphocyte mediated immunity GO:0002449 139 0.121
hindbrain development GO:0030902 128 0.120
positive regulation of ras gtpase activity GO:0032320 65 0.120
regulation of response to wounding GO:1903034 189 0.119
ureteric bud morphogenesis GO:0060675 62 0.119
cardiac muscle cell differentiation GO:0055007 69 0.119
regulation of hormone levels GO:0010817 211 0.119
Rat
somatotropin secreting cell differentiation GO:0060126 4 0.119
respiratory tube development GO:0030323 167 0.119
bone resorption GO:0045453 38 0.118
negative regulation of sterol transport GO:0032372 4 0.118
germ cell development GO:0007281 185 0.117
regulation of fat cell differentiation GO:0045598 81 0.117
detection of external stimulus GO:0009581 61 0.117
blood vessel morphogenesis GO:0048514 285 0.117
positive regulation of cell division GO:0051781 31 0.116
glial cell differentiation GO:0010001 131 0.115
regulation of ureteric bud formation GO:0072106 3 0.115
cell fate specification GO:0001708 72 0.115
cardiac chamber morphogenesis GO:0003206 93 0.114
tissue remodeling GO:0048771 102 0.114
prostate gland development GO:0030850 48 0.112
detection of mechanical stimulus involved in equilibrioception GO:0050973 2 0.112
respiratory system development GO:0060541 190 0.112
oligopeptide transmembrane transport GO:0035672 4 0.112
immune effector process GO:0002252 321 0.111
membrane depolarization GO:0051899 64 0.111
cardiac muscle cell action potential GO:0086001 11 0.110
Human
cochlea development GO:0090102 35 0.110
organonitrogen compound biosynthetic process GO:1901566 192 0.109
leukocyte differentiation GO:0002521 342 0.109
cardiac muscle hypertrophy GO:0003300 23 0.109
mapk cascade GO:0000165 281 0.109
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.109
positive regulation of cell motility GO:2000147 116 0.109
inner cell mass cell differentiation GO:0001826 7 0.108
kidney development GO:0001822 213 0.108
skeletal muscle fiber development GO:0048741 58 0.108
inner ear receptor stereocilium organization GO:0060122 23 0.108
negative regulation of glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000734 1 0.108
nucleotide metabolic process GO:0009117 332 0.108
neurotransmitter uptake GO:0001504 14 0.107
regulation of purine nucleotide catabolic process GO:0033121 122 0.107
purine ribonucleotide catabolic process GO:0009154 208 0.107
sympathetic nervous system development GO:0048485 22 0.106
auditory receptor cell development GO:0060117 20 0.106
negative regulation of glial cell proliferation GO:0060253 4 0.106
cellular response to organic cyclic compound GO:0071407 87 0.106
Human
regulation of gtp catabolic process GO:0033124 113 0.105
cognition GO:0050890 149 0.104
interleukin 13 secretion GO:0072611 2 0.103
regulation of cell migration GO:0030334 219 0.103
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.103
fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000699 1 0.103
histamine induced gastric acid secretion GO:0001697 1 0.102
mating GO:0007618 27 0.102
meiotic cell cycle GO:0051321 122 0.101
regulation of map kinase activity GO:0043405 120 0.100
regulation of cytoskeleton organization GO:0051493 122 0.100
positive regulation of map kinase activity GO:0043406 84 0.099
ureter maturation GO:0035799 4 0.099
mesonephric tubule development GO:0072164 94 0.098
regulation of anatomical structure size GO:0090066 178 0.098
epithelial cell proliferation involved in prostatic bud elongation GO:0060517 1 0.098
cellular amide metabolic process GO:0043603 58 0.098
positive regulation of neuron apoptotic process GO:0043525 25 0.097
appendage morphogenesis GO:0035107 149 0.097
cell differentiation involved in kidney development GO:0061005 33 0.097
negative regulation of neuron differentiation GO:0045665 101 0.096
morphogenesis of embryonic epithelium GO:0016331 159 0.095
muscle hypertrophy GO:0014896 24 0.095
regulation of ras gtpase activity GO:0032318 88 0.094
negative regulation of endothelial cell differentiation GO:0045602 2 0.094
regulation of transporter activity GO:0032409 57 0.094
mesenchymal cell development GO:0014031 93 0.094
trabecula morphogenesis GO:0061383 40 0.094
kidney morphogenesis GO:0060993 83 0.093
mitral valve morphogenesis GO:0003183 4 0.093
endothelial cell development GO:0001885 20 0.093
regulation of proteolysis GO:0030162 164 0.092
ureteric bud development GO:0001657 94 0.091
gliogenesis GO:0042063 141 0.090
regulation of organelle organization GO:0033043 289 0.089
cardiocyte differentiation GO:0035051 87 0.089
regulation of striated muscle contraction GO:0006942 25 0.089
Human
potassium ion import GO:0010107 1 0.088
cell cell signaling involved in kidney development GO:0060995 2 0.088
branching morphogenesis of an epithelial tube GO:0048754 159 0.088
mesonephric duct formation GO:0072181 2 0.087
epithelial cell morphogenesis GO:0003382 41 0.087
stress activated mapk cascade GO:0051403 80 0.087
regulation of heart growth GO:0060420 31 0.087
positive regulation of cell development GO:0010720 237 0.087
production of molecular mediator of immune response GO:0002440 103 0.087
positive regulation of cytokine production GO:0001819 174 0.087
pallium development GO:0021543 120 0.086
regulation of tissue remodeling GO:0034103 38 0.086
sensory perception of chemical stimulus GO:0007606 51 0.085
paraxial mesodermal cell differentiation GO:0048342 2 0.085
odontogenesis of dentin containing tooth GO:0042475 66 0.085
cellular calcium ion homeostasis GO:0006874 119 0.085
multi multicellular organism process GO:0044706 109 0.085
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.084
inorganic anion transport GO:0015698 43 0.084
macromolecule catabolic process GO:0009057 281 0.084
heart growth GO:0060419 45 0.083
telencephalon development GO:0021537 186 0.083
gonad development GO:0008406 141 0.083
Rat
regulation of neural precursor cell proliferation GO:2000177 70 0.083
small gtpase mediated signal transduction GO:0007264 97 0.083
nephron morphogenesis GO:0072028 69 0.083
pattern specification involved in metanephros development GO:0072268 4 0.083
actin cytoskeleton reorganization GO:0031532 21 0.082
adaptive immune response GO:0002250 155 0.082
negative regulation of fat cell differentiation GO:0045599 36 0.082
regulation of carbohydrate metabolic process GO:0006109 75 0.082
regulation of neuron projection development GO:0010975 169 0.082
positive regulation of transferase activity GO:0051347 167 0.081
actin filament bundle assembly GO:0051017 40 0.080
foregut morphogenesis GO:0007440 12 0.080
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.080
gene looping GO:0090202 2 0.080
regulation of glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000733 1 0.079
cilium assembly GO:0042384 81 0.079
kidney epithelium development GO:0072073 121 0.079
lens development in camera type eye GO:0002088 62 0.078
purine nucleotide catabolic process GO:0006195 211 0.078
amino acid import into cell GO:1902837 4 0.078
negative regulation of phosphorus metabolic process GO:0010563 184 0.078
regulation of multi organism process GO:0043900 111 0.078
negative regulation of cell proliferation GO:0008285 296 0.078
endocardial cell differentiation GO:0060956 4 0.078
carbohydrate metabolic process GO:0005975 230 0.077
regulation of inositol trisphosphate biosynthetic process GO:0032960 3 0.077
positive regulation of transcription regulatory region dna binding GO:2000679 1 0.077
nuclear division GO:0000280 158 0.076
intracellular protein transport GO:0006886 204 0.076
glomerular mesangial cell differentiation GO:0072008 3 0.076
positive regulation of neuron migration GO:2001224 5 0.076
photoreceptor cell differentiation GO:0046530 52 0.076
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.076
habenula development GO:0021986 2 0.076
neuron death GO:0070997 154 0.075
regulation of interleukin 13 secretion GO:2000665 2 0.075
positive regulation of secretion by cell GO:1903532 114 0.075
morphogenesis of a polarized epithelium GO:0001738 37 0.074
mammary gland morphogenesis GO:0060443 54 0.074
cardiac right atrium morphogenesis GO:0003213 3 0.074
l glutamate uptake involved in synaptic transmission GO:0051935 3 0.074
blastocyst development GO:0001824 80 0.074
mesenchyme development GO:0060485 152 0.074
mesenchyme morphogenesis GO:0072132 32 0.074
regulation of retina development in camera type eye GO:1902866 3 0.074
limbic system development GO:0021761 72 0.073
multi organism reproductive behavior GO:0044705 29 0.073
lymphoid progenitor cell differentiation GO:0002320 17 0.072

Kcnq1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.626
disease of anatomical entity DOID:7 0 0.626
Human
nervous system disease DOID:863 0 0.626
auditory system disease DOID:2742 0 0.537
nonsyndromic deafness DOID:0050563 0 0.537