Mus musculus

17 known processes

Kcnq2

potassium voltage-gated channel, subfamily Q, member 2

(Aliases: KQT2,Nmf134,HNSPC)

Kcnq2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
inorganic ion transmembrane transport GO:0098660 234 0.958
Mouse Worm
transmembrane transport GO:0055085 412 0.949
Mouse Worm Fly
inorganic cation transmembrane transport GO:0098662 207 0.948
Mouse Worm
synaptic transmission GO:0007268 329 0.945
ion transmembrane transport GO:0034220 361 0.932
Mouse Worm Fly
regulation of ion transport GO:0043269 215 0.904
Mouse Fly
locomotory behavior GO:0007626 195 0.793
cation transmembrane transport GO:0098655 266 0.756
Mouse Worm Fly
multicellular organismal response to stress GO:0033555 62 0.695
calcium ion transmembrane transport GO:0070588 85 0.682
regulation of heart contraction GO:0008016 77 0.673
Fly
divalent inorganic cation transport GO:0072511 178 0.672
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.605
regulation of blood circulation GO:1903522 93 0.597
Fly
positive regulation of heart rate GO:0010460 10 0.590
somatostatin receptor signaling pathway GO:0038169 2 0.563
regulation of postsynaptic membrane potential GO:0060078 48 0.562
g protein coupled receptor signaling pathway GO:0007186 243 0.523
Worm
learning or memory GO:0007611 148 0.514
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.509
opioid receptor signaling pathway GO:0038003 5 0.508
response to organonitrogen compound GO:0010243 246 0.493
associative learning GO:0008306 61 0.484
regulation of synaptic transmission glutamatergic GO:0051966 19 0.483
calcium ion transport GO:0006816 159 0.482
regulation of membrane potential GO:0042391 192 0.481
synapse organization GO:0050808 125 0.479
neuron neuron synaptic transmission GO:0007270 69 0.473
regulation of voltage gated calcium channel activity GO:1901385 4 0.466
regulation of neurotransmitter transport GO:0051588 35 0.465
regulation of system process GO:0044057 200 0.459
Fly
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.446
positive regulation of the force of heart contraction by chemical signal GO:0003099 3 0.425
learning GO:0007612 98 0.423
cation transport GO:0006812 399 0.413
Mouse Worm Fly
regulation of cellular amine metabolic process GO:0033238 20 0.411
sensory perception GO:0007600 245 0.409
Mouse
synaptic transmission involved in micturition GO:0060084 3 0.401
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.388
cellular amine metabolic process GO:0044106 44 0.387
action potential GO:0001508 78 0.380
dendrite development GO:0016358 115 0.376
glutamate receptor signaling pathway GO:0007215 35 0.368
neurotransmitter transport GO:0006836 76 0.366
regulation of saliva secretion GO:0046877 2 0.361
regulation of neurotransmitter levels GO:0001505 87 0.360
nucleobase containing small molecule metabolic process GO:0055086 352 0.352
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.352
regulation of transmembrane transport GO:0034762 128 0.337
Mouse Fly
regulation of muscle contraction GO:0006937 49 0.337
conditioned taste aversion GO:0001661 4 0.335
generation of ovulation cycle rhythm GO:0060112 1 0.320
heart contraction GO:0060047 93 0.318
Fly
regulation of nucleoside metabolic process GO:0009118 130 0.317
membrane depolarization GO:0051899 64 0.314
regulation of synaptic plasticity GO:0048167 87 0.307
central nervous system neuron differentiation GO:0021953 162 0.305
pancreatic a cell fate commitment GO:0003326 2 0.302
circulatory system process GO:0003013 197 0.299
Fly
cellular ketone metabolic process GO:0042180 84 0.298
purine nucleotide metabolic process GO:0006163 302 0.297
pancreatic pp cell differentiation GO:0003312 2 0.295
nucleotide metabolic process GO:0009117 332 0.294
regulation of metal ion transport GO:0010959 106 0.288
adult behavior GO:0030534 135 0.287
cation homeostasis GO:0055080 212 0.286
regulation of ion transmembrane transport GO:0034765 119 0.285
Mouse Fly
neurotransmitter secretion GO:0007269 62 0.283
regulation of purine nucleotide metabolic process GO:1900542 169 0.282
heart process GO:0003015 94 0.281
Fly
positive regulation of neuron differentiation GO:0045666 141 0.268
glial cell development GO:0021782 54 0.267
divalent inorganic cation homeostasis GO:0072507 138 0.266
purine ribonucleotide metabolic process GO:0009150 290 0.266
diencephalon development GO:0021536 63 0.263
membrane hyperpolarization GO:0060081 21 0.262
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.261
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.261
positive regulation of synaptic plasticity GO:0031915 4 0.258
divalent metal ion transport GO:0070838 172 0.257
response to radiation GO:0009314 165 0.252
memory GO:0007613 58 0.246
regulation of cation channel activity GO:2001257 22 0.246
organonitrogen compound biosynthetic process GO:1901566 192 0.245
sodium ion transmembrane transport GO:0035725 49 0.243
ribose phosphate metabolic process GO:0019693 291 0.240
guanosine containing compound catabolic process GO:1901069 144 0.240
adult locomotory behavior GO:0008344 91 0.236
adult walking behavior GO:0007628 41 0.235
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.233
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.230
circadian rhythm GO:0007623 114 0.230
regulation of neurotransmitter secretion GO:0046928 29 0.230
positive regulation of nervous system development GO:0051962 221 0.230
regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback GO:0001978 5 0.225
actin cytoskeleton organization GO:0030036 220 0.222
regulation of neuron differentiation GO:0045664 281 0.221
purine nucleoside triphosphate metabolic process GO:0009144 226 0.221
hindbrain development GO:0030902 128 0.220
regulation of cellular ketone metabolic process GO:0010565 66 0.219
regulation of circadian rhythm GO:0042752 58 0.219
nucleoside phosphate metabolic process GO:0006753 338 0.215
sensory perception of mechanical stimulus GO:0050954 107 0.213
Mouse
response to pain GO:0048265 26 0.212
organic hydroxy compound transport GO:0015850 93 0.211
aromatic compound catabolic process GO:0019439 286 0.211
somatostatin signaling pathway GO:0038170 2 0.210
regulation of ion transmembrane transporter activity GO:0032412 54 0.210
sclerotome development GO:0061056 4 0.206
sensory perception of pain GO:0019233 47 0.202
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.202
response to light stimulus GO:0009416 135 0.198
response to ammonium ion GO:0060359 21 0.197
forebrain development GO:0030900 302 0.197
histamine induced gastric acid secretion GO:0001697 1 0.196
substrate independent telencephalic tangential migration GO:0021826 8 0.196
forebrain cell migration GO:0021885 58 0.191
visual learning GO:0008542 44 0.190
amine metabolic process GO:0009308 45 0.187
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.185
neuromuscular process GO:0050905 99 0.185
organic anion transport GO:0015711 137 0.184
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.184
regulation of nucleotide metabolic process GO:0006140 169 0.183
ribonucleotide metabolic process GO:0009259 291 0.182
muscle contraction GO:0006936 101 0.175
Fly
cognition GO:0050890 149 0.175
regulation of neuron projection development GO:0010975 169 0.175
regulation of organelle organization GO:0033043 289 0.174
striated muscle contraction GO:0006941 45 0.173
Fly
regulation of purine nucleotide catabolic process GO:0033121 122 0.173
positive regulation of nucleotide metabolic process GO:0045981 114 0.173
regulation of nucleotide catabolic process GO:0030811 122 0.170
purine containing compound metabolic process GO:0072521 311 0.169
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.169
positive regulation of dopamine secretion GO:0033603 2 0.168
regulation of muscle system process GO:0090257 80 0.167
circadian sleep wake cycle rem sleep GO:0042747 1 0.166
regulation of glial cell differentiation GO:0045685 41 0.165
nucleoside triphosphate catabolic process GO:0009143 205 0.164
lateral geniculate nucleus development GO:0021771 1 0.164
organonitrogen compound catabolic process GO:1901565 264 0.164
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.162
nucleoside triphosphate metabolic process GO:0009141 230 0.161
carbohydrate metabolic process GO:0005975 230 0.157
positive regulation of gtpase activity GO:0043547 85 0.157
limbic system development GO:0021761 72 0.156
dopamine metabolic process GO:0042417 23 0.156
cerebellum development GO:0021549 77 0.156
cellular potassium ion transport GO:0071804 43 0.154
Mouse Worm
regulation of secretion GO:0051046 274 0.154
g protein coupled receptor internalization GO:0002031 3 0.153
nucleoside catabolic process GO:0009164 206 0.153
membrane organization GO:0061024 245 0.153
positive regulation of secretion GO:0051047 130 0.152
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.152
response to organic cyclic compound GO:0014070 198 0.151
synaptic transmission glutamatergic GO:0035249 36 0.151
neuron migration GO:0001764 122 0.149
regulation of neuronal synaptic plasticity GO:0048168 30 0.148
digestion GO:0007586 40 0.148
cellular ion homeostasis GO:0006873 165 0.143
regulation of anatomical structure size GO:0090066 178 0.142
positive regulation of gtp catabolic process GO:0033126 85 0.142
fear response GO:0042596 33 0.141
regulation of cell projection organization GO:0031344 206 0.141
regulation of lyase activity GO:0051339 13 0.140
ribonucleoside triphosphate catabolic process GO:0009203 199 0.140
gastrin induced gastric acid secretion GO:0001698 1 0.136
rhythmic process GO:0048511 174 0.133
heterocycle catabolic process GO:0046700 280 0.133
glycosyl compound catabolic process GO:1901658 206 0.132
response to alkaloid GO:0043279 34 0.132
smooth muscle contraction GO:0006939 44 0.131
sa node cell action potential GO:0086015 4 0.131
astrocyte fate commitment GO:0060018 4 0.130
cellular protein complex assembly GO:0043623 116 0.129
regulation of cell migration GO:0030334 219 0.129
ras protein signal transduction GO:0007265 77 0.128
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.128
response to cocaine GO:0042220 14 0.128
regulation of protein transport GO:0051223 163 0.126
regulation of nucleotide biosynthetic process GO:0030808 34 0.125
regulation of dopamine secretion GO:0014059 9 0.124
catecholamine metabolic process GO:0006584 30 0.123
gtp catabolic process GO:0006184 143 0.123
sodium ion transport GO:0006814 73 0.121
blood circulation GO:0008015 195 0.121
Fly
negative regulation of action potential GO:0045759 1 0.120
purine containing compound biosynthetic process GO:0072522 70 0.120
body fluid secretion GO:0007589 53 0.118
second messenger mediated signaling GO:0019932 73 0.118
positive regulation of neuron projection development GO:0010976 79 0.117
fertilization GO:0009566 127 0.114
cyclic nucleotide biosynthetic process GO:0009190 44 0.114
cellular chemical homeostasis GO:0055082 215 0.114
sensitization GO:0046960 2 0.113
muscle system process GO:0003012 141 0.111
Fly
developmental maturation GO:0021700 193 0.111
regulation of cell motility GO:2000145 236 0.110
regulation of cellular component biogenesis GO:0044087 181 0.110
skeletal system development GO:0001501 356 0.109
ribonucleoside catabolic process GO:0042454 206 0.109
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.109
positive regulation of nucleoside metabolic process GO:0045979 91 0.109
regulation of heart rate GO:0002027 36 0.108
Fly
cell type specific apoptotic process GO:0097285 268 0.108
regulation of g protein activated inward rectifier potassium channel activity GO:1900128 1 0.107
regulation of smooth muscle contraction GO:0006940 22 0.106
nerve development GO:0021675 67 0.106
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.105
regulation of camp biosynthetic process GO:0030817 25 0.104
positive regulation of nucleotide catabolic process GO:0030813 88 0.104
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.104
purine nucleoside catabolic process GO:0006152 205 0.104
synaptic vesicle localization GO:0097479 59 0.103
positive regulation of secretion by cell GO:1903532 114 0.103
organic cyclic compound catabolic process GO:1901361 295 0.102
camera type eye development GO:0043010 266 0.102
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.102
neural retina development GO:0003407 41 0.102
ear morphogenesis GO:0042471 118 0.102
Mouse
regulation of tube size GO:0035150 57 0.100
guanosine containing compound metabolic process GO:1901068 144 0.100
nitrogen compound transport GO:0071705 271 0.100
carbohydrate derivative catabolic process GO:1901136 231 0.100
carbohydrate derivative biosynthetic process GO:1901137 183 0.099
positive regulation of cell division GO:0051781 31 0.098
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.097
purine containing compound catabolic process GO:0072523 213 0.097
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 4 0.097
positive regulation of kinase activity GO:0033674 155 0.096
nucleotide biosynthetic process GO:0009165 78 0.096
circadian sleep wake cycle non rem sleep GO:0042748 2 0.096
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.094
gabaergic neuron differentiation GO:0097154 11 0.094
monocarboxylic acid metabolic process GO:0032787 191 0.093
angiogenesis GO:0001525 201 0.093
regulation of calcium ion transmembrane transport GO:1903169 20 0.091
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.091
stem cell differentiation GO:0048863 268 0.090
visceral serous pericardium development GO:0061032 2 0.090
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.089
positive regulation of organelle organization GO:0010638 128 0.089
regulation of t cell activation GO:0050863 170 0.089
forebrain neuron differentiation GO:0021879 52 0.088
regulation of cell activation GO:0050865 289 0.087
purine ribonucleotide catabolic process GO:0009154 208 0.087
globus pallidus development GO:0021759 2 0.087
glial cell differentiation GO:0010001 131 0.086
positive regulation of cellular catabolic process GO:0031331 148 0.086
positive regulation of synaptic transmission glutamatergic GO:0051968 8 0.086
regulation of cellular amino acid metabolic process GO:0006521 5 0.086
organophosphate catabolic process GO:0046434 232 0.086
cytosolic calcium ion homeostasis GO:0051480 70 0.085
nucleoside phosphate catabolic process GO:1901292 222 0.085
visual behavior GO:0007632 45 0.085
regulation of cellular catabolic process GO:0031329 242 0.085
mapk cascade GO:0000165 281 0.085
erk1 and erk2 cascade GO:0070371 77 0.084
mesenchymal cell development GO:0014031 93 0.084
vesicle localization GO:0051648 86 0.084
purine nucleotide biosynthetic process GO:0006164 65 0.084
detection of external stimulus GO:0009581 61 0.084
dopamine receptor signaling pathway GO:0007212 16 0.084
cellular calcium ion homeostasis GO:0006874 119 0.083
purine ribonucleotide biosynthetic process GO:0009152 59 0.083
positive regulation of high voltage gated calcium channel activity GO:1901843 1 0.083
negative regulation of intracellular signal transduction GO:1902532 167 0.083
metencephalon development GO:0022037 89 0.083
astrocyte differentiation GO:0048708 43 0.082
sensory perception of light stimulus GO:0050953 54 0.082
purine ribonucleoside catabolic process GO:0046130 205 0.082
regulation of gtp catabolic process GO:0033124 113 0.081
operant conditioning GO:0035106 2 0.081
endomembrane system organization GO:0010256 147 0.081
nucleoside metabolic process GO:0009116 246 0.080
regulation of ras protein signal transduction GO:0046578 114 0.080
purine nucleoside metabolic process GO:0042278 241 0.080
cellular response to temperature stimulus GO:0071502 2 0.079
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.079
somatotropin secreting cell differentiation GO:0060126 4 0.079
serotonin receptor signaling pathway GO:0007210 8 0.079
renal system development GO:0072001 225 0.077
transmission of nerve impulse GO:0019226 76 0.077
retina development in camera type eye GO:0060041 119 0.077
cell proliferation in hindbrain GO:0021534 10 0.077
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.077
ribonucleotide biosynthetic process GO:0009260 59 0.076
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.075
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.075
dopamine transport GO:0015872 15 0.075
lung pattern specification process GO:0060432 1 0.074
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.074
regulation of secretion by cell GO:1903530 249 0.074
cellular nitrogen compound catabolic process GO:0044270 280 0.073
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.073
metal ion homeostasis GO:0055065 189 0.073
protein polymerization GO:0051258 57 0.072
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.072
cellular metal ion homeostasis GO:0006875 151 0.072
regulation of reproductive process GO:2000241 66 0.072
mitochondrion organization GO:0007005 134 0.072
potassium ion transmembrane transport GO:0071805 43 0.071
Mouse Worm
spinal cord development GO:0021510 81 0.071
optic nerve development GO:0021554 8 0.071
sensory perception of sound GO:0007605 97 0.071
Mouse
sensory organ morphogenesis GO:0090596 242 0.070
Mouse
auditory receptor cell fate specification GO:0042667 1 0.070
regulation of inward rectifier potassium channel activity GO:1901979 1 0.070
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.070
inter male aggressive behavior GO:0002121 3 0.070
ribonucleoside triphosphate metabolic process GO:0009199 220 0.069
long term synaptic potentiation GO:0060291 25 0.069
catecholamine transport GO:0051937 21 0.069
multi organism behavior GO:0051705 62 0.069
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.069
multicellular organismal signaling GO:0035637 91 0.068
intracellular protein transport GO:0006886 204 0.068
mitochondrion distribution GO:0048311 4 0.068
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.068
cellular divalent inorganic cation homeostasis GO:0072503 127 0.067
interneuron migration from the subpallium to the cortex GO:0021830 7 0.067
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 8 0.066
kidney development GO:0001822 213 0.066
cranial nerve development GO:0021545 41 0.066
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.066
regulation of cellular component size GO:0032535 121 0.065
negative regulation of cell development GO:0010721 169 0.064
axonogenesis GO:0007409 274 0.064
regulation of circadian sleep wake cycle non rem sleep GO:0045188 1 0.064
cardiac muscle contraction GO:0060048 32 0.064
Fly
detection of mechanical stimulus involved in sensory perception GO:0050974 23 0.063
purine ribonucleoside metabolic process GO:0046128 241 0.063
extrinsic apoptotic signaling pathway GO:0097191 126 0.061
visual perception GO:0007601 52 0.061
cellular response to organonitrogen compound GO:0071417 145 0.061
cerebral cortex neuron differentiation GO:0021895 19 0.060
mesenchyme development GO:0060485 152 0.060
positive regulation of blood circulation GO:1903524 22 0.060
response to decreased oxygen levels GO:0036293 59 0.060
axon guidance GO:0007411 141 0.060
glycosyl compound metabolic process GO:1901657 246 0.060
positive regulation of heart contraction GO:0045823 14 0.060
positive regulation of protein phosphorylation GO:0001934 242 0.059
monoamine transport GO:0015844 33 0.059
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.059
anion transport GO:0006820 177 0.059
positive regulation of protein modification process GO:0031401 299 0.058
stem cell development GO:0048864 219 0.058
urogenital system development GO:0001655 261 0.058
engulfment of apoptotic cell GO:0043652 3 0.057
regulation of actin filament based process GO:0032970 99 0.057
ribonucleotide catabolic process GO:0009261 208 0.056
phospholipid metabolic process GO:0006644 87 0.056
negative regulation of phosphorus metabolic process GO:0010563 184 0.055
positive regulation of ras gtpase activity GO:0032320 65 0.055
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.055
cerebral cortex gabaergic interneuron development GO:0021894 6 0.055
leukocyte differentiation GO:0002521 342 0.055
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.054
cerebellar cortex development GO:0021695 48 0.054
regulation of protein localization GO:0032880 231 0.054
response to peptide GO:1901652 136 0.054
ribonucleoside metabolic process GO:0009119 245 0.054
retina morphogenesis in camera type eye GO:0060042 45 0.053
regulation of fat cell differentiation GO:0045598 81 0.053
acid secretion GO:0046717 33 0.053
muscle tissue development GO:0060537 308 0.053
telencephalon development GO:0021537 186 0.053
regulation of catecholamine metabolic process GO:0042069 10 0.053
regulation of dopamine metabolic process GO:0042053 10 0.053
cyclic purine nucleotide metabolic process GO:0052652 43 0.053
positive regulation of cellular amine metabolic process GO:0033240 5 0.053
camp metabolic process GO:0046058 40 0.053
exocytosis GO:0006887 121 0.052
regulation of peptide secretion GO:0002791 77 0.052
positive regulation of glycolytic process GO:0045821 4 0.052
positive regulation of ion transmembrane transport GO:0034767 24 0.052
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.052
menarche GO:0042696 1 0.052
ribose phosphate biosynthetic process GO:0046390 59 0.051
atrioventricular node cell fate commitment GO:0060929 1 0.051
gland development GO:0048732 330 0.051
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.051
microtubule based process GO:0007017 236 0.050
microtubule polymerization or depolymerization GO:0031109 26 0.050
calcium ion homeostasis GO:0055074 127 0.050
forebrain neuron development GO:0021884 30 0.050
regulation of transporter activity GO:0032409 57 0.050
negative regulation of cellular component organization GO:0051129 194 0.049
nucleoside phosphate biosynthetic process GO:1901293 79 0.049
positive regulation of synaptic transmission gabaergic GO:0032230 8 0.049
protein localization to membrane GO:0072657 108 0.049
positive regulation of dendrite development GO:1900006 21 0.048
myeloid leukocyte differentiation GO:0002573 119 0.048
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 7 0.048
habituation GO:0046959 3 0.048
positive regulation of catecholamine secretion GO:0033605 2 0.048
amino acid transport GO:0006865 61 0.048
negative regulation of serotonin secretion GO:0014063 2 0.047
central nervous system projection neuron axonogenesis GO:0021952 21 0.047
immune effector process GO:0002252 321 0.047
response to peptide hormone GO:0043434 127 0.047
negative regulation of protein metabolic process GO:0051248 282 0.047
pancreatic pp cell fate commitment GO:0003329 2 0.047
regulation of retina development in camera type eye GO:1902866 3 0.047
response to steroid hormone GO:0048545 56 0.047
detection of stimulus involved in sensory perception GO:0050906 44 0.047
ossification GO:0001503 216 0.046
organic hydroxy compound metabolic process GO:1901615 203 0.046
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.046
cellular homeostasis GO:0019725 240 0.046
positive regulation of transmembrane transport GO:0034764 29 0.046
fast calcium ion dependent exocytosis of neurotransmitter GO:0098746 1 0.045
purine nucleoside triphosphate catabolic process GO:0009146 203 0.045
synaptic transmission cholinergic GO:0007271 7 0.045
neuronal action potential GO:0019228 54 0.045
retinal cone cell development GO:0046549 8 0.045
regulation of systemic arterial blood pressure by baroreceptor feedback GO:0003025 7 0.045
adrenergic receptor signaling pathway GO:0071875 13 0.044
regulation of camp metabolic process GO:0030814 30 0.044
generation of precursor metabolites and energy GO:0006091 103 0.044
detection of stimulus GO:0051606 84 0.044
nucleotide catabolic process GO:0009166 217 0.044
mechanoreceptor differentiation GO:0042490 67 0.044
detection of abiotic stimulus GO:0009582 60 0.044
telencephalon cell migration GO:0022029 55 0.044
negative regulation of organelle organization GO:0010639 90 0.044
organic acid transport GO:0015849 101 0.044
positive regulation of cell projection organization GO:0031346 95 0.044
organelle fission GO:0048285 170 0.044
lymphocyte differentiation GO:0030098 242 0.044
organelle localization GO:0051640 179 0.044
regulation of muscle tissue development GO:1901861 97 0.044
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.044
regulation of body fluid levels GO:0050878 162 0.043
gliogenesis GO:0042063 141 0.043
forebrain generation of neurons GO:0021872 63 0.043
regulation of mapk cascade GO:0043408 248 0.043
behavioral defense response GO:0002209 28 0.043
macromolecule catabolic process GO:0009057 281 0.043
glucose homeostasis GO:0042593 128 0.043
regulation of multi organism process GO:0043900 111 0.043
neuron death GO:0070997 154 0.043
regulation of neural retina development GO:0061074 3 0.043
epithelial cell development GO:0002064 159 0.041
fat cell differentiation GO:0045444 160 0.041
regulation of erk1 and erk2 cascade GO:0070372 71 0.041
cell maturation GO:0048469 127 0.041
endocytosis GO:0006897 168 0.041
central nervous system neuron axonogenesis GO:0021955 28 0.041
ameboidal type cell migration GO:0001667 128 0.040
auditory receptor cell fate determination GO:0042668 3 0.040
positive regulation of cell development GO:0010720 237 0.040
dopamine secretion GO:0014046 9 0.040
cerebellar purkinje cell layer development GO:0021680 26 0.040
pallium development GO:0021543 120 0.040
mitral valve development GO:0003174 4 0.040
response to endoplasmic reticulum stress GO:0034976 53 0.039
cellular amino acid metabolic process GO:0006520 103 0.039
cell division GO:0051301 120 0.039
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 3 0.039
response to hypoxia GO:0001666 58 0.039
gtp metabolic process GO:0046039 144 0.039
regulation of white fat cell proliferation GO:0070350 2 0.039
camp mediated signaling GO:0019933 15 0.039
covalent chromatin modification GO:0016569 163 0.039
sensory system development GO:0048880 3 0.039
regulation of gliogenesis GO:0014013 50 0.039
regulation of osteoblast differentiation GO:0045667 67 0.039
cyclic nucleotide metabolic process GO:0009187 59 0.038
central nervous system neuron development GO:0021954 67 0.038
anatomical structure homeostasis GO:0060249 145 0.038
cell proliferation in external granule layer GO:0021924 10 0.038
peptidyl amino acid modification GO:0018193 336 0.038
regulation of neuron death GO:1901214 134 0.038
cerebellar cortex formation GO:0021697 22 0.038
neuromuscular process controlling posture GO:0050884 14 0.038
germ cell development GO:0007281 185 0.038
negative regulation of phosphate metabolic process GO:0045936 184 0.037
negative regulation of secretion GO:0051048 61 0.037
actin filament organization GO:0007015 113 0.037
protein modification by small protein conjugation GO:0032446 187 0.037
t cell activation GO:0042110 289 0.037
deltoid tuberosity development GO:0035993 3 0.037
positive regulation of calcium ion transmembrane transporter activity GO:1901021 8 0.037
neuron apoptotic process GO:0051402 142 0.037
peripheral nervous system development GO:0007422 53 0.037
regulation of sensory perception of pain GO:0051930 8 0.037
negative regulation of neuron apoptotic process GO:0043524 92 0.037
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.037
hippocampus development GO:0021766 52 0.036
positive regulation of cellular component biogenesis GO:0044089 94 0.036

Kcnq2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
renal tubular transport disease DOID:447 0 0.043
bartter disease DOID:445 0 0.043
kidney disease DOID:557 0 0.043
disease of anatomical entity DOID:7 0 0.043
urinary system disease DOID:18 0 0.043