Mus musculus

0 known processes

Kdelr3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

(Aliases: AI173274)

Kdelr3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
extracellular matrix organization GO:0030198 147 0.739
protein hydroxylation GO:0018126 4 0.619
extracellular structure organization GO:0043062 148 0.513
collagen fibril organization GO:0030199 32 0.463
wound healing GO:0042060 157 0.153
skeletal system development GO:0001501 356 0.152
connective tissue development GO:0061448 179 0.113
positive regulation of cell death GO:0010942 224 0.101
cellular response to acid chemical GO:0071229 68 0.085
cell substrate adhesion GO:0031589 130 0.083
oxidation reduction process GO:0055114 342 0.081
fibrinolysis GO:0042730 3 0.077
membrane raft assembly GO:0001765 3 0.077
extrinsic apoptotic signaling pathway GO:0097191 126 0.074
regulation of chondrocyte differentiation GO:0032330 33 0.070
glycoprotein metabolic process GO:0009100 116 0.067
cellular amino acid metabolic process GO:0006520 103 0.065
ossification GO:0001503 216 0.064
regulation of apoptotic signaling pathway GO:2001233 197 0.064
cartilage development GO:0051216 140 0.060
chromatin organization GO:0006325 206 0.058
regulation of vesicle mediated transport GO:0060627 139 0.055
monocarboxylic acid metabolic process GO:0032787 191 0.053
peptidyl proline hydroxylation GO:0019511 3 0.052
multi multicellular organism process GO:0044706 109 0.051
angiogenesis GO:0001525 201 0.050
signal transduction in absence of ligand GO:0038034 55 0.049
immune effector process GO:0002252 321 0.049
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.048
regulation of organelle organization GO:0033043 289 0.046
endochondral bone morphogenesis GO:0060350 50 0.046
collagen biosynthetic process GO:0032964 7 0.046
anion transport GO:0006820 177 0.046
ras protein signal transduction GO:0007265 77 0.044
peptidyl amino acid modification GO:0018193 336 0.044
regulation of integrin mediated signaling pathway GO:2001044 8 0.044
head morphogenesis GO:0060323 34 0.043
cellular modified amino acid metabolic process GO:0006575 63 0.042
small gtpase mediated signal transduction GO:0007264 97 0.042
fat cell differentiation GO:0045444 160 0.040
endomembrane system organization GO:0010256 147 0.040
bone development GO:0060348 120 0.039
response to organic cyclic compound GO:0014070 198 0.039
regulation of cell substrate adhesion GO:0010810 73 0.039
cellular ketone metabolic process GO:0042180 84 0.039
apoptotic signaling pathway GO:0097190 306 0.038
response to acid chemical GO:0001101 111 0.038
synaptic transmission GO:0007268 329 0.037
epithelial to mesenchymal transition GO:0001837 47 0.037
spermatogenesis GO:0007283 284 0.037
cation transport GO:0006812 399 0.037
regulation of response to wounding GO:1903034 189 0.037
regulation of cell motility GO:2000145 236 0.036
regulation of cell adhesion GO:0030155 154 0.036
protein maturation GO:0051604 176 0.034
synaptic transmission cholinergic GO:0007271 7 0.034
positive regulation of cell substrate adhesion GO:0010811 47 0.034
cell matrix adhesion GO:0007160 68 0.034
peptidyl proline modification GO:0018208 6 0.033
cerebral cortex development GO:0021987 86 0.033
regulation of body fluid levels GO:0050878 162 0.032
lung development GO:0030324 164 0.032
organic acid transport GO:0015849 101 0.032
male gamete generation GO:0048232 285 0.032
cytoplasmic transport GO:0016482 234 0.031
cell adhesion GO:0007155 329 0.030
digestive tract development GO:0048565 190 0.030
ameboidal type cell migration GO:0001667 128 0.029
chondrocyte differentiation GO:0002062 72 0.028
regulation of bone mineralization GO:0030500 31 0.028
localization within membrane GO:0051668 4 0.027
glycosyl compound metabolic process GO:1901657 246 0.027
multicellular organismal macromolecule metabolic process GO:0044259 19 0.027
response to hypoxia GO:0001666 58 0.026
positive regulation of interleukin 6 secretion GO:2000778 1 0.026
positive regulation of programmed cell death GO:0043068 218 0.026
respiratory tube development GO:0030323 167 0.026
tissue homeostasis GO:0001894 115 0.026
fibril organization GO:0097435 2 0.026
sphingolipid biosynthetic process GO:0030148 26 0.026
regulation of immunological synapse formation GO:2000520 2 0.025
regulation of protein kinase activity GO:0045859 232 0.025
negative regulation of cell proliferation GO:0008285 296 0.025
defense response to other organism GO:0098542 197 0.024
chondrocyte development GO:0002063 24 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
regulation of cell cycle GO:0051726 281 0.024
negative regulation of gastrulation GO:2000542 3 0.024
stem cell development GO:0048864 219 0.024
peripheral nervous system axon regeneration GO:0014012 2 0.023
carboxylic acid transport GO:0046942 100 0.023
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.023
replacement ossification GO:0036075 26 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
peptidyl proline hydroxylation to 4 hydroxy l proline GO:0018401 2 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.022
cell type specific apoptotic process GO:0097285 268 0.022
epithelial cell proliferation GO:0050673 174 0.022
regulation of hydrolase activity GO:0051336 246 0.022
multicellular organismal homeostasis GO:0048871 164 0.022
engulfment of apoptotic cell GO:0043652 3 0.022
cellular amine metabolic process GO:0044106 44 0.022
vesicle organization GO:0016050 60 0.022
regulation of cell migration GO:0030334 219 0.021
covalent chromatin modification GO:0016569 163 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
blood vessel morphogenesis GO:0048514 285 0.021
response to organonitrogen compound GO:0010243 246 0.021
oligosaccharide biosynthetic process GO:0009312 7 0.020
cellular component assembly involved in morphogenesis GO:0010927 139 0.020
biomineral tissue development GO:0031214 64 0.020
t cell activation GO:0042110 289 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
positive regulation of fatty acid oxidation GO:0046321 4 0.020
membrane organization GO:0061024 245 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.019
negative regulation of dna replication GO:0008156 4 0.019
bone mineralization GO:0030282 54 0.019
regulation of cellular amine metabolic process GO:0033238 20 0.019
forebrain development GO:0030900 302 0.019
regulation of cytokine production GO:0001817 266 0.019
regulation of ossification GO:0030278 112 0.019
regulation of peptidase activity GO:0052547 96 0.019
regulation of endocytosis GO:0030100 69 0.019
regulation of cellular component biogenesis GO:0044087 181 0.018
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.018
response to decreased oxygen levels GO:0036293 59 0.018
response to inorganic substance GO:0010035 96 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
cellular chemical homeostasis GO:0055082 215 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
lipid transport GO:0006869 98 0.018
early endosome to late endosome transport GO:0045022 2 0.017
regulation of sphingolipid biosynthetic process GO:0090153 1 0.017
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.017
protein heterotrimerization GO:0070208 8 0.017
carbohydrate metabolic process GO:0005975 230 0.017
telencephalon development GO:0021537 186 0.017
divalent inorganic cation transport GO:0072511 178 0.017
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.017
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.017
activation of immune response GO:0002253 138 0.017
membrane lipid biosynthetic process GO:0046467 32 0.017
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.017
integrin mediated signaling pathway GO:0007229 27 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
anatomical structure homeostasis GO:0060249 145 0.016
regulation of mast cell differentiation GO:0060375 3 0.016
copii coated vesicle budding GO:0090114 2 0.016
organic anion transport GO:0015711 137 0.016
amine metabolic process GO:0009308 45 0.016
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.016
4 hydroxyproline metabolic process GO:0019471 5 0.016
extracellular fibril organization GO:0043206 2 0.016
proteoglycan metabolic process GO:0006029 38 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
transmembrane transport GO:0055085 412 0.016
immune response regulating signaling pathway GO:0002764 125 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
organophosphate catabolic process GO:0046434 232 0.016
response to oxygen levels GO:0070482 62 0.015
bone morphogenesis GO:0060349 78 0.015
regulation of proteolysis GO:0030162 164 0.015
protein heterooligomerization GO:0051291 14 0.015
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.015
positive regulation of cell adhesion GO:0045785 80 0.015
mesenchymal cell differentiation GO:0048762 107 0.015
metal ion homeostasis GO:0055065 189 0.015
myotube differentiation GO:0014902 105 0.015
regulation of cartilage development GO:0061035 44 0.015
response to epidermal growth factor GO:0070849 4 0.015
antimicrobial peptide production GO:0002775 2 0.015
positive regulation of protein modification process GO:0031401 299 0.015
ceramide biosynthetic process GO:0046513 20 0.014
striated muscle tissue development GO:0014706 293 0.014
rho protein signal transduction GO:0007266 32 0.014
protein localization to organelle GO:0033365 185 0.014
regulation of epithelial to mesenchymal transition GO:0010717 22 0.014
regulation of secretion by cell GO:1903530 249 0.014
golgi vesicle transport GO:0048193 30 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
coagulation GO:0050817 78 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.014
negative regulation of phagocytosis GO:0050765 4 0.014
macromolecule catabolic process GO:0009057 281 0.014
integrin biosynthetic process GO:0045112 1 0.014
protein catabolic process GO:0030163 221 0.014
protein folding GO:0006457 28 0.014
phagocytosis GO:0006909 66 0.014
skeletal system morphogenesis GO:0048705 203 0.014
acetylcholine secretion neurotransmission GO:0014055 2 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
multicellular organismal signaling GO:0035637 91 0.014
i kappab kinase nf kappab signaling GO:0007249 85 0.014
negative regulation of immune effector process GO:0002698 55 0.014
ear development GO:0043583 200 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
small molecule catabolic process GO:0044282 71 0.013
sensory perception of mechanical stimulus GO:0050954 107 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
macromolecule glycosylation GO:0043413 55 0.013
camera type eye development GO:0043010 266 0.013
negative regulation of molecular function GO:0044092 258 0.013
collagen metabolic process GO:0032963 17 0.013
fatty acid metabolic process GO:0006631 121 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
notochord development GO:0030903 20 0.013
response to calcium ion GO:0051592 20 0.013
stem cell differentiation GO:0048863 268 0.013
sensory perception GO:0007600 245 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
calcium ion homeostasis GO:0055074 127 0.013
respiratory system development GO:0060541 190 0.013
chondroblast differentiation GO:0060591 2 0.013
circadian regulation of gene expression GO:0032922 48 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
cellular response to oxidative stress GO:0034599 76 0.013
regulation of exit from mitosis GO:0007096 1 0.013
nucleoside catabolic process GO:0009164 206 0.013
regulation of system process GO:0044057 200 0.013
regulation of endopeptidase activity GO:0052548 89 0.012
cell recognition GO:0008037 83 0.012
purine nucleotide metabolic process GO:0006163 302 0.012
heterocycle catabolic process GO:0046700 280 0.012
regulation of transferase activity GO:0051338 263 0.012
blood coagulation GO:0007596 76 0.012
regulation of cellular amino acid metabolic process GO:0006521 5 0.012
retinal blood vessel morphogenesis GO:0061304 3 0.012
multi organism reproductive behavior GO:0044705 29 0.012
trabecula formation GO:0060343 24 0.012
regulation of norepinephrine secretion GO:0014061 2 0.012
regulation of interleukin 8 production GO:0032677 3 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
response to organophosphorus GO:0046683 22 0.012
multicellular organismal catabolic process GO:0044243 7 0.012
cellular water homeostasis GO:0009992 2 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
astrocyte fate commitment GO:0060018 4 0.012
cardiac muscle tissue development GO:0048738 130 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
appendage development GO:0048736 166 0.012
cardiac chamber morphogenesis GO:0003206 93 0.012
striated muscle cell development GO:0055002 125 0.012
negative regulation of synapse maturation GO:2000297 2 0.012
dna metabolic process GO:0006259 303 0.011
divalent metal ion transport GO:0070838 172 0.011
mesenchymal cell development GO:0014031 93 0.011
histone modification GO:0016570 159 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
protein secretion GO:0009306 111 0.011
cellular response to external stimulus GO:0071496 88 0.011
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.011
heart morphogenesis GO:0003007 178 0.011
antibacterial peptide secretion GO:0002779 1 0.011
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.011
vitamin d biosynthetic process GO:0042368 3 0.011
regulation of cell cycle process GO:0010564 160 0.011
regulation of ceramide biosynthetic process GO:2000303 1 0.011
organic hydroxy compound transport GO:0015850 93 0.011
regulation of action potential GO:0098900 4 0.011
muscle tissue morphogenesis GO:0060415 53 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
response to temperature stimulus GO:0009266 55 0.011
positive regulation of cell motility GO:2000147 116 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
negative regulation of cell motility GO:2000146 61 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
regulation of t cell activation GO:0050863 170 0.011
norepinephrine transport GO:0015874 2 0.011
positive regulation of cell migration GO:0030335 109 0.011
phenol containing compound metabolic process GO:0018958 60 0.011
cellular ion homeostasis GO:0006873 165 0.011
single organism cell adhesion GO:0098602 156 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
cellular response to lipid GO:0071396 145 0.010
mitotic cell cycle process GO:1903047 159 0.010
cardiac muscle tissue morphogenesis GO:0055008 44 0.010
response to metal ion GO:0010038 47 0.010
sensory system development GO:0048880 3 0.010
negative regulation of cell migration GO:0030336 59 0.010
cell killing GO:0001906 67 0.010
antimicrobial peptide biosynthetic process GO:0002777 2 0.010
regulation of secretion GO:0051046 274 0.010
negative regulation of macrophage chemotaxis GO:0010760 1 0.010
t cell mediated cytotoxicity GO:0001913 26 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
intussusceptive angiogenesis GO:0002041 2 0.010
negative regulation of anoikis GO:2000811 2 0.010
mitotic cytokinesis GO:0000281 4 0.010
cellular response to abiotic stimulus GO:0071214 56 0.010
sclerotome development GO:0061056 4 0.010
regulation of protein secretion GO:0050708 82 0.010
regulation of fibrinolysis GO:0051917 1 0.010

Kdelr3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.505
musculoskeletal system disease DOID:17 0 0.505
connective tissue disease DOID:65 0 0.505
bone development disease DOID:0080006 0 0.221
bone disease DOID:0080001 0 0.221
osteochondrodysplasia DOID:2256 0 0.186
myopathy DOID:423 0 0.047
muscular disease DOID:0080000 0 0.047
muscle tissue disease DOID:66 0 0.047
heart disease DOID:114 0 0.041
cardiomyopathy DOID:0050700 0 0.041
cardiovascular system disease DOID:1287 0 0.041
nervous system disease DOID:863 0 0.041
congenital muscular dystrophy DOID:0050557 0 0.039
muscular dystrophy DOID:9884 0 0.039
osteogenesis imperfecta DOID:12347 0 0.034
neuromuscular disease DOID:440 0 0.030
charcot marie tooth disease DOID:10595 0 0.030
neuropathy DOID:870 0 0.030
intrinsic cardiomyopathy DOID:0060036 0 0.026
collagen disease DOID:854 0 0.022
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.018
eye disease DOID:5614 0 0.018
retinal disease DOID:5679 0 0.014
retinal degeneration DOID:8466 0 0.014