Mus musculus

223 known processes

Kdm1a

lysine (K)-specific demethylase 1A

(Aliases: AA408884,Aof2,D4Ertd478e,Kdm1,Lsd1,1810043O07Rik,mKIAA0601)

Kdm1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone modification GO:0016570 159 0.992
covalent chromatin modification GO:0016569 163 0.991
chromatin organization GO:0006325 206 0.986
chromatin modification GO:0016568 187 0.978
histone methylation GO:0016571 71 0.889
peptidyl lysine modification GO:0018205 77 0.857
histone h2a ubiquitination GO:0033522 3 0.845
protein dealkylation GO:0008214 13 0.845
dna metabolic process GO:0006259 303 0.726
histone lysine demethylation GO:0070076 13 0.715
histone demethylation GO:0016577 13 0.707
cell fate commitment GO:0045165 210 0.688
peptidyl amino acid modification GO:0018193 336 0.684
macromolecule methylation GO:0043414 120 0.681
protein demethylation GO:0006482 13 0.673
oocyte axis specification GO:0007309 2 0.645
protein methylation GO:0006479 81 0.636
methylation GO:0032259 134 0.582
histone h3 k36 demethylation GO:0070544 2 0.576
histone h2a monoubiquitination GO:0035518 1 0.568
regulation of histone methylation GO:0031060 30 0.541
demethylation GO:0070988 23 0.507
regulation of organelle organization GO:0033043 289 0.476
internal protein amino acid acetylation GO:0006475 42 0.453
protein modification by small protein conjugation or removal GO:0070647 207 0.423
pole plasm assembly GO:0007315 2 0.400
cell maturation GO:0048469 127 0.387
regulation of chromatin modification GO:1903308 57 0.384
negative regulation of protein modification process GO:0031400 163 0.373
oocyte construction GO:0007308 2 0.369
positive regulation of immature t cell proliferation GO:0033091 4 0.313
negative regulation of chromatin modification GO:1903309 19 0.304
intracellular mrna localization GO:0008298 4 0.285
positive regulation of chromosome organization GO:2001252 33 0.276
protein alkylation GO:0008213 81 0.275
positive regulation of chromatin modification GO:1903310 28 0.264
regionalization GO:0003002 337 0.262
negative regulation of organelle organization GO:0010639 90 0.240
regulation of mrna processing GO:0050684 41 0.235
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.223
mrna processing GO:0006397 63 0.220
tube formation GO:0035148 140 0.220
spermatogenesis GO:0007283 284 0.220
axonogenesis GO:0007409 274 0.213
cellular response to lipid GO:0071396 145 0.211
meiotic cell cycle GO:0051321 122 0.207
histone monoubiquitination GO:0010390 3 0.199
dna methylation GO:0006306 43 0.199
organelle fission GO:0048285 170 0.194
nuclear division GO:0000280 158 0.188
regulation of cell cycle GO:0051726 281 0.184
protein acylation GO:0043543 64 0.182
oocyte anterior posterior axis specification GO:0007314 2 0.179
regulation of transcription during meiosis GO:0051037 1 0.178
neural tube formation GO:0001841 108 0.175
internal peptidyl lysine acetylation GO:0018393 42 0.172
histone lysine methylation GO:0034968 50 0.166
stem cell development GO:0048864 219 0.165
wnt signaling pathway GO:0016055 188 0.165
germ cell development GO:0007281 185 0.161
neural tube development GO:0021915 160 0.157
dna modification GO:0006304 50 0.154
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.152
macromolecule catabolic process GO:0009057 281 0.151
dna alkylation GO:0006305 43 0.146
posttranscriptional gene silencing GO:0016441 10 0.145
development of primary sexual characteristics GO:0045137 143 0.143
positive regulation of histone modification GO:0031058 28 0.139
mrna splicing via spliceosome GO:0000398 43 0.136
cellular amino acid metabolic process GO:0006520 103 0.135
positive regulation of organelle organization GO:0010638 128 0.133
epithelial tube formation GO:0072175 130 0.132
developmental maturation GO:0021700 193 0.130
histone acetylation GO:0016573 41 0.130
regulation of cell cycle process GO:0010564 160 0.128
regulation of wnt signaling pathway GO:0030111 123 0.128
regulation of mitotic cell cycle GO:0007346 126 0.127
aromatic compound catabolic process GO:0019439 286 0.125
epithelial tube morphogenesis GO:0060562 303 0.124
meiotic nuclear division GO:0007126 115 0.123
regulation of histone modification GO:0031056 56 0.122
gene silencing by rna GO:0031047 19 0.120
negative regulation of cellular protein metabolic process GO:0032269 247 0.118
neural tube closure GO:0001843 90 0.116
negative regulation of histone modification GO:0031057 18 0.115
cellular nitrogen compound catabolic process GO:0044270 280 0.115
mrna metabolic process GO:0016071 84 0.115
posttranscriptional regulation of gene expression GO:0010608 155 0.110
positive regulation of protein modification process GO:0031401 299 0.110
negative regulation of histone methylation GO:0031061 10 0.109
cellular ketone metabolic process GO:0042180 84 0.108
regulation of protein stability GO:0031647 52 0.108
regulation of cellular amine metabolic process GO:0033238 20 0.107
camera type eye development GO:0043010 266 0.106
mitotic cell cycle GO:0000278 195 0.105
embryonic epithelial tube formation GO:0001838 130 0.103
posttranscriptional gene silencing by rna GO:0035194 10 0.102
protein catabolic process GO:0030163 221 0.102
organelle assembly GO:0070925 177 0.100
cellular response to dna damage stimulus GO:0006974 207 0.095
Human
histone h3 k9 dimethylation GO:0036123 4 0.095
dna repair GO:0006281 107 0.095
positive regulation of histone h3 k9 methylation GO:0051574 4 0.093
fourth ventricle development GO:0021592 2 0.092
tube closure GO:0060606 91 0.091
transcription from rna polymerase i promoter GO:0006360 13 0.090
protein ubiquitination GO:0016567 171 0.090
morphogenesis of embryonic epithelium GO:0016331 159 0.089
negative regulation of cell proliferation GO:0008285 296 0.086
regulation of chromatin silencing GO:0031935 2 0.086
regulation of rna splicing GO:0043484 37 0.086
engulfment of apoptotic cell GO:0043652 3 0.085
protein modification by small protein conjugation GO:0032446 187 0.083
axon guidance GO:0007411 141 0.078
negative regulation of cellular component organization GO:0051129 194 0.078
regulation of mrna metabolic process GO:1903311 43 0.076
response to organic cyclic compound GO:0014070 198 0.075
regulation of cell cycle phase transition GO:1901987 77 0.075
rna processing GO:0006396 105 0.075
multi multicellular organism process GO:0044706 109 0.073
gene silencing GO:0016458 38 0.072
histone deacetylation GO:0016575 26 0.071
histone ubiquitination GO:0016574 10 0.071
oogenesis GO:0048477 56 0.071
striated muscle tissue development GO:0014706 293 0.071
cell division GO:0051301 120 0.070
regulation of histone h3 k9 methylation GO:0051570 8 0.070
neuron apoptotic process GO:0051402 142 0.070
regulation of cellular amino acid metabolic process GO:0006521 5 0.069
regulation of mrna splicing via spliceosome GO:0048024 32 0.069
rna interference GO:0016246 2 0.068
regulation of histone h3 k36 methylation GO:0000414 1 0.067
rna splicing via transesterification reactions GO:0000375 43 0.067
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.066
regulation of apoptotic signaling pathway GO:2001233 197 0.065
Human
gonad development GO:0008406 141 0.064
histone h3 k27 demethylation GO:0071557 4 0.064
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.062
Human
circadian rhythm GO:0007623 114 0.062
nucleoside phosphate metabolic process GO:0006753 338 0.061
regulation of mitotic cell cycle phase transition GO:1901990 73 0.060
ribonucleoprotein complex subunit organization GO:0071826 28 0.060
protein deacetylation GO:0006476 32 0.058
histone h3 k36 methylation GO:0010452 6 0.057
apoptotic signaling pathway GO:0097190 306 0.057
Human
b cell activation GO:0042113 161 0.057
glycosyl compound catabolic process GO:1901658 206 0.057
regulation of neuron differentiation GO:0045664 281 0.056
histone h3 k4 methylation GO:0051568 23 0.056
neural precursor cell proliferation GO:0061351 121 0.056
regulation of transcription by chromatin organization GO:0034401 0 0.056
transcription from rna polymerase iii promoter GO:0006383 3 0.055
positive regulation of cell development GO:0010720 237 0.054
ribonucleoside metabolic process GO:0009119 245 0.054
organic cyclic compound catabolic process GO:1901361 295 0.054
skeletal system morphogenesis GO:0048705 203 0.053
segmentation GO:0035282 93 0.053
nucleoside phosphate catabolic process GO:1901292 222 0.052
heterocycle catabolic process GO:0046700 280 0.052
skeletal system development GO:0001501 356 0.052
cell adhesion GO:0007155 329 0.052
chromatin silencing at rdna GO:0000183 3 0.051
nucleoside monophosphate catabolic process GO:0009125 59 0.051
nucleoside triphosphate catabolic process GO:0009143 205 0.051
regulation of neuron death GO:1901214 134 0.051
ribonucleotide metabolic process GO:0009259 291 0.051
blastocyst development GO:0001824 80 0.050
regulation of cellular ketone metabolic process GO:0010565 66 0.050
peptidyl lysine acetylation GO:0018394 45 0.049
placenta development GO:0001890 140 0.049
regulation of meiotic cell cycle GO:0051445 34 0.048
regulation of chromatin organization GO:1902275 57 0.048
neuron death GO:0070997 154 0.048
lymphocyte differentiation GO:0030098 242 0.047
rhythmic process GO:0048511 174 0.046
b cell proliferation GO:0042100 53 0.045
positive regulation of apoptotic process GO:0043065 217 0.045
double strand break repair GO:0006302 48 0.045
histone h4 acetylation GO:0043967 10 0.045
intrinsic apoptotic signaling pathway GO:0097193 132 0.045
Human
protein autophosphorylation GO:0046777 61 0.045
snrna metabolic process GO:0016073 1 0.044
rna splicing GO:0008380 54 0.043
t cell activation GO:0042110 289 0.043
neural tube patterning GO:0021532 43 0.042
positive regulation of nervous system development GO:0051962 221 0.042
maternal determination of anterior posterior axis embryo GO:0008358 2 0.042
purine nucleotide metabolic process GO:0006163 302 0.042
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.041
neuron projection guidance GO:0097485 141 0.041
cellular macromolecule catabolic process GO:0044265 206 0.040
regulation of cell division GO:0051302 76 0.040
intracellular receptor signaling pathway GO:0030522 74 0.040
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.039
nucleotide catabolic process GO:0009166 217 0.038
ubiquitin dependent protein catabolic process GO:0006511 129 0.037
lymphocyte mediated immunity GO:0002449 139 0.037
positive regulation of hh target transcription factor activity GO:0007228 3 0.036
nucleoside monophosphate metabolic process GO:0009123 85 0.036
peptidyl lysine methylation GO:0018022 29 0.036
leukocyte differentiation GO:0002521 342 0.036
regulation of cell activation GO:0050865 289 0.036
hindbrain development GO:0030902 128 0.036
purine containing compound metabolic process GO:0072521 311 0.035
locomotory behavior GO:0007626 195 0.035
positive regulation of lymphocyte differentiation GO:0045621 61 0.035
cellular protein catabolic process GO:0044257 155 0.035
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.034
regulation of cell projection organization GO:0031344 206 0.034
negative regulation of mitotic cell cycle GO:0045930 58 0.034
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.034
negative regulation of transcription from rna polymerase i promoter GO:0016479 2 0.034
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.034
leukocyte proliferation GO:0070661 172 0.033
purine nucleoside triphosphate catabolic process GO:0009146 203 0.033
positive regulation of histone methylation GO:0031062 16 0.033
purine nucleoside metabolic process GO:0042278 241 0.033
glycosyl compound metabolic process GO:1901657 246 0.033
negative regulation of neuron death GO:1901215 98 0.033
macromolecule deacylation GO:0098732 37 0.033
epithelial to mesenchymal transition GO:0001837 47 0.033
alternative mrna splicing via spliceosome GO:0000380 12 0.033
ribose phosphate metabolic process GO:0019693 291 0.032
rna localization GO:0006403 23 0.032
muscle tissue development GO:0060537 308 0.032
oocyte development GO:0048599 33 0.032
regulation of nuclear division GO:0051783 56 0.032
positive regulation of b cell activation GO:0050871 49 0.031
negative regulation of chromatin silencing GO:0031936 1 0.031
purine nucleoside monophosphate catabolic process GO:0009128 58 0.031
regulation of leukocyte differentiation GO:1902105 159 0.031
cell type specific apoptotic process GO:0097285 268 0.030
mesenchymal cell differentiation GO:0048762 107 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.030
positive regulation of growth GO:0045927 104 0.030
regulation of response to wounding GO:1903034 189 0.030
nucleotide metabolic process GO:0009117 332 0.030
response to nutrient levels GO:0031667 109 0.029
positive regulation of cell death GO:0010942 224 0.029
modification dependent macromolecule catabolic process GO:0043632 133 0.029
ribonucleotide catabolic process GO:0009261 208 0.029
regulation of t cell proliferation GO:0042129 92 0.029
cell growth GO:0016049 130 0.029
male gamete generation GO:0048232 285 0.029
female gamete generation GO:0007292 74 0.029
regulation of cell growth GO:0001558 91 0.028
atp catabolic process GO:0006200 55 0.028
purine nucleoside monophosphate metabolic process GO:0009126 81 0.028
oocyte differentiation GO:0009994 35 0.028
mitotic cell cycle process GO:1903047 159 0.028
chronological cell aging GO:0001300 1 0.028
histone h3 k9 demethylation GO:0033169 5 0.028
protein deacylation GO:0035601 36 0.028
negative regulation of proteolysis GO:0045861 74 0.028
positive regulation of t cell activation GO:0050870 101 0.028
response to radiation GO:0009314 165 0.027
regulation of binding GO:0051098 111 0.027
Human
chemotaxis GO:0006935 247 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
positive regulation of cell activation GO:0050867 158 0.027
sensory perception of sound GO:0007605 97 0.027
lateral inhibition GO:0046331 1 0.027
cell aging GO:0007569 35 0.027
signal transduction by p53 class mediator GO:0072331 51 0.027
Human
response to molecule of bacterial origin GO:0002237 143 0.026
rostrocaudal neural tube patterning GO:0021903 12 0.026
response to drug GO:0042493 75 0.026
response to reactive oxygen species GO:0000302 56 0.026
cellular amine metabolic process GO:0044106 44 0.026
heterochromatin organization GO:0070828 4 0.026
mesenchymal cell development GO:0014031 93 0.026
cellular response to sterol GO:0036315 2 0.026
telencephalon development GO:0021537 186 0.025
stem cell division GO:0017145 30 0.025
positive regulation of leukocyte differentiation GO:1902107 86 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
odontogenesis GO:0042476 78 0.025
connective tissue development GO:0061448 179 0.025
sensory organ morphogenesis GO:0090596 242 0.025
positive regulation of apoptotic signaling pathway GO:2001235 95 0.024
ribonucleoside monophosphate catabolic process GO:0009158 57 0.024
organophosphate catabolic process GO:0046434 232 0.024
ras protein signal transduction GO:0007265 77 0.024
response to organonitrogen compound GO:0010243 246 0.024
stem cell differentiation GO:0048863 268 0.024
regulation of intracellular transport GO:0032386 159 0.024
regulation of neural precursor cell proliferation GO:2000177 70 0.024
positive regulation of cell projection organization GO:0031346 95 0.024
regulation of establishment of protein localization GO:0070201 181 0.024
regulation of t cell activation GO:0050863 170 0.024
cellular response to molecule of bacterial origin GO:0071219 83 0.024
negative regulation of molecular function GO:0044092 258 0.024
Human
response to inorganic substance GO:0010035 96 0.024
regulation of lymphocyte proliferation GO:0050670 117 0.024
mitotic cytokinesis GO:0000281 4 0.023
positive regulation of t cell differentiation in thymus GO:0033089 13 0.023
protein targeting GO:0006605 143 0.023
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.023
amine metabolic process GO:0009308 45 0.023
response to acid chemical GO:0001101 111 0.023
regulation of protein localization GO:0032880 231 0.023
negative regulation of neuron apoptotic process GO:0043524 92 0.023
lateral ventricle development GO:0021670 11 0.023
lymphocyte proliferation GO:0046651 164 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
skeletal muscle organ development GO:0060538 163 0.023
production of molecular mediator of immune response GO:0002440 103 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.022
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.022
Human
protein localization to nucleus GO:0034504 121 0.022
nucleoside metabolic process GO:0009116 246 0.022
adaptive immune response GO:0002250 155 0.022
epithelial cell development GO:0002064 159 0.022
dendrite development GO:0016358 115 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.022
memory GO:0007613 58 0.022
transdifferentiation GO:0060290 1 0.022
angiogenesis GO:0001525 201 0.022
positive regulation of lymphocyte activation GO:0051251 140 0.022
endodermal cell fate commitment GO:0001711 12 0.022
negative regulation of chromosome organization GO:2001251 30 0.022
response to lipopolysaccharide GO:0032496 128 0.021
formation of organ boundary GO:0010160 1 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
olfactory learning GO:0008355 2 0.021
regulation of neuron apoptotic process GO:0043523 122 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
regulation of histone h3 k4 methylation GO:0051569 12 0.021
somatic diversification of immune receptors GO:0002200 53 0.021
snrna processing GO:0016180 1 0.021
mesenchyme development GO:0060485 152 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.021
developmental growth involved in morphogenesis GO:0060560 138 0.021
blood vessel morphogenesis GO:0048514 285 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
embryonic skeletal system development GO:0048706 120 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
regulation of leukocyte proliferation GO:0070663 121 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
t cell proliferation GO:0042098 120 0.020
interferon gamma production GO:0032609 67 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
regulation of odontogenesis GO:0042481 18 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
protein monoubiquitination GO:0006513 11 0.020
myeloid leukocyte differentiation GO:0002573 119 0.020
modification dependent protein catabolic process GO:0019941 133 0.020
negative regulation of cell cycle phase transition GO:1901988 48 0.020
regulation of hormone levels GO:0010817 211 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.020
multicellular organismal aging GO:0010259 24 0.020
regulation of phospholipid biosynthetic process GO:0071071 3 0.019
response to alcohol GO:0097305 48 0.019
positive regulation of wnt signaling pathway GO:0030177 45 0.019
ribonucleoside monophosphate metabolic process GO:0009161 80 0.019
somatic cell dna recombination GO:0016444 51 0.019
cytoplasmic transport GO:0016482 234 0.019
circadian regulation of gene expression GO:0032922 48 0.019
positive regulation of neuron differentiation GO:0045666 141 0.019
cellular lipid metabolic process GO:0044255 323 0.019
response to steroid hormone GO:0048545 56 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.019
endocytosis GO:0006897 168 0.019
membrane organization GO:0061024 245 0.018
regulation of cysteine type endopeptidase activity GO:2000116 65 0.018
ossification GO:0001503 216 0.018
positive regulation of cytokine production GO:0001819 174 0.018
multicellular organism growth GO:0035264 161 0.018
stem cell maintenance GO:0019827 130 0.018
histone h3 k9 methylation GO:0051567 17 0.018
cognition GO:0050890 149 0.018
sensory organ boundary specification GO:0008052 1 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
myeloid cell differentiation GO:0030099 233 0.018
maintenance of location GO:0051235 89 0.018
maintenance of protein location in nucleus GO:0051457 2 0.017
regulation of peptidyl lysine acetylation GO:2000756 22 0.017
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.017
Human
bone mineralization GO:0030282 54 0.017
snrna 3 end processing GO:0034472 1 0.017
regulation of neuron projection development GO:0010975 169 0.017
regulation of cell cycle g2 m phase transition GO:1902749 10 0.017
spermatid development GO:0007286 108 0.017
regulation of peptidase activity GO:0052547 96 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
positive regulation of t cell differentiation GO:0045582 52 0.017
glucose homeostasis GO:0042593 128 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
purine containing compound catabolic process GO:0072523 213 0.017
response to sterol GO:0036314 4 0.017
positive regulation of protein transport GO:0051222 93 0.017
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.016
Human
regulation of transferase activity GO:0051338 263 0.016
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
regulation of chromosome organization GO:0033044 83 0.016
gene silencing by mirna GO:0035195 10 0.016
digestive tract morphogenesis GO:0048546 147 0.016
neuron migration GO:0001764 122 0.016
response to light stimulus GO:0009416 135 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
erythrocyte differentiation GO:0030218 88 0.016
wound healing GO:0042060 157 0.016
positive regulation of t cell proliferation GO:0042102 52 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
positive regulation of retinoic acid receptor signaling pathway GO:0048386 3 0.016
negative regulation of gene silencing GO:0060969 2 0.016
protein localization to organelle GO:0033365 185 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
response to growth factor GO:0070848 198 0.015
muscle cell differentiation GO:0042692 261 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
forebrain development GO:0030900 302 0.015
pallium development GO:0021543 120 0.015
nuclear import GO:0051170 95 0.015
gastrulation GO:0007369 116 0.015
positive regulation of cell cycle GO:0045787 92 0.015
regulation of protein catabolic process GO:0042176 108 0.015
cell cell signaling involved in cell fate commitment GO:0045168 35 0.015
acylglycerol metabolic process GO:0006639 55 0.015
sensory perception GO:0007600 245 0.015
compound eye development GO:0048749 1 0.015
mitotic cell cycle checkpoint GO:0007093 31 0.015
endodermal cell fate specification GO:0001714 4 0.015
regulation of myeloid cell differentiation GO:0045637 96 0.015
action potential GO:0001508 78 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
asymmetric neuroblast division GO:0055059 1 0.015
protein import GO:0017038 101 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
spliceosomal complex disassembly GO:0000390 1 0.015
midbrain hindbrain boundary development GO:0030917 9 0.014
genitalia development GO:0048806 37 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
regulation of protein transport GO:0051223 163 0.014
response to ionizing radiation GO:0010212 42 0.014
asymmetric stem cell division GO:0098722 3 0.014
antimicrobial peptide biosynthetic process GO:0002777 2 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
cellular response to retinoic acid GO:0071300 25 0.014
regulation of defense response GO:0031347 233 0.014
cell cycle checkpoint GO:0000075 47 0.014
nucleoside catabolic process GO:0009164 206 0.014
epidermis development GO:0008544 187 0.014
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.014
dna recombination GO:0006310 92 0.014
male meiosis i GO:0007141 16 0.014
cardiac chamber morphogenesis GO:0003206 93 0.014
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.014
response to temperature stimulus GO:0009266 55 0.014
negative regulation of circadian rhythm GO:0042754 8 0.014
embryonic placenta development GO:0001892 98 0.014
mitotic spindle checkpoint GO:0071174 9 0.013
negative regulation of cell cycle GO:0045786 123 0.013
microtubule based process GO:0007017 236 0.013
immunoglobulin mediated immune response GO:0016064 69 0.013
bone development GO:0060348 120 0.013
respiratory tube development GO:0030323 167 0.013
positive regulation of immature t cell proliferation in thymus GO:0033092 3 0.013
maintenance of apical basal cell polarity GO:0035090 3 0.013
neutral lipid metabolic process GO:0006638 57 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.013
protein processing GO:0016485 163 0.013
response to retinoic acid GO:0032526 56 0.013
immunoglobulin production GO:0002377 73 0.013
regulation of dna recombination GO:0000018 34 0.013
response to extracellular stimulus GO:0009991 127 0.013
atp metabolic process GO:0046034 75 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
regulation of cytokine production GO:0001817 266 0.013
regulation of proteolysis GO:0030162 164 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
cartilage development GO:0051216 140 0.013
cellular response to oxidative stress GO:0034599 76 0.013
regulation of tooth mineralization GO:0070170 2 0.012
chromatin remodeling GO:0006338 32 0.012
regulation of cell adhesion GO:0030155 154 0.012
protein dna complex subunit organization GO:0071824 28 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
negative regulation of dna recombination GO:0045910 13 0.012
triglyceride metabolic process GO:0006641 51 0.012
signal transduction downstream of smoothened GO:0007227 4 0.012
spinal cord development GO:0021510 81 0.012
carbohydrate homeostasis GO:0033500 128 0.012
leukocyte mediated immunity GO:0002443 174 0.012

Kdm1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.081
nervous system disease DOID:863 0 0.081
disease of cellular proliferation DOID:14566 0 0.058
cancer DOID:162 0 0.043
organ system cancer DOID:0050686 0 0.042
central nervous system disease DOID:331 0 0.028
sensory system disease DOID:0050155 0 0.027
eye and adnexa disease DOID:1492 0 0.027
eye disease DOID:5614 0 0.026
neurodegenerative disease DOID:1289 0 0.017