Mus musculus

0 known processes

Kdm3b

KDM3B lysine (K)-specific demethylase 3B

(Aliases: JHDM2B,mKIAA1082,Jmjd1b,5830462I21Rik)

Kdm3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone methylation GO:0016571 71 0.288
Mouse
histone modification GO:0016570 159 0.217
Mouse
histone lysine methylation GO:0034968 50 0.131
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.129
myeloid cell differentiation GO:0030099 233 0.114
protein polyubiquitination GO:0000209 33 0.111
covalent chromatin modification GO:0016569 163 0.110
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.096
regulation of histone modification GO:0031056 56 0.096
Mouse
macromolecule catabolic process GO:0009057 281 0.093
protein modification by small protein conjugation GO:0032446 187 0.086
protein ubiquitination GO:0016567 171 0.079
multicellular organism growth GO:0035264 161 0.079
lung development GO:0030324 164 0.078
protein methylation GO:0006479 81 0.067
Mouse
leukocyte differentiation GO:0002521 342 0.064
chromatin organization GO:0006325 206 0.063
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.061
negative regulation of protein metabolic process GO:0051248 282 0.060
Mouse
regulation of chromatin modification GO:1903308 57 0.057
Mouse
compound eye development GO:0048749 1 0.050
peptidyl amino acid modification GO:0018193 336 0.050
Mouse
protein alkylation GO:0008213 81 0.050
Mouse
respiratory tube development GO:0030323 167 0.050
negative regulation of cellular protein metabolic process GO:0032269 247 0.050
Mouse
macromolecule methylation GO:0043414 120 0.046
Mouse
dna metabolic process GO:0006259 303 0.046
negative regulation of cellular component organization GO:0051129 194 0.045
Mouse
cellular ketone metabolic process GO:0042180 84 0.045
wnt signaling pathway GO:0016055 188 0.044
amine metabolic process GO:0009308 45 0.043
regulation of cell cycle GO:0051726 281 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
regulation of cellular ketone metabolic process GO:0010565 66 0.039
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.039
organic cyclic compound catabolic process GO:1901361 295 0.038
rhythmic process GO:0048511 174 0.036
protein deacetylation GO:0006476 32 0.036
ubiquitin dependent protein catabolic process GO:0006511 129 0.035
regulation of cellular catabolic process GO:0031329 242 0.035
cellular amino acid metabolic process GO:0006520 103 0.034
immune effector process GO:0002252 321 0.034
chromatin modification GO:0016568 187 0.033
Mouse
skeletal system development GO:0001501 356 0.033
modification dependent macromolecule catabolic process GO:0043632 133 0.032
morphogenesis of embryonic epithelium GO:0016331 159 0.032
purine nucleotide metabolic process GO:0006163 302 0.032
regionalization GO:0003002 337 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.031
proteasomal protein catabolic process GO:0010498 98 0.030
positive regulation of dna templated transcription elongation GO:0032786 2 0.029
negative regulation of molecular function GO:0044092 258 0.029
negative regulation of protein modification process GO:0031400 163 0.029
Mouse
respiratory system development GO:0060541 190 0.029
camera type eye development GO:0043010 266 0.029
neural tube development GO:0021915 160 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.028
apoptotic signaling pathway GO:0097190 306 0.028
heterocycle catabolic process GO:0046700 280 0.028
regulation of chromosome organization GO:0033044 83 0.027
Mouse
peptidyl lysine modification GO:0018205 77 0.026
Mouse
gland development GO:0048732 330 0.026
dna repair GO:0006281 107 0.026
tube formation GO:0035148 140 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
stem cell maintenance GO:0019827 130 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
negative regulation of cell proliferation GO:0008285 296 0.025
negative regulation of chromatin silencing GO:0031936 1 0.024
reactive oxygen species metabolic process GO:0072593 84 0.024
limb development GO:0060173 166 0.024
heart morphogenesis GO:0003007 178 0.024
protein acylation GO:0043543 64 0.024
negative regulation of nervous system development GO:0051961 156 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
blastocyst development GO:0001824 80 0.023
mrna metabolic process GO:0016071 84 0.023
aromatic compound catabolic process GO:0019439 286 0.023
developmental maturation GO:0021700 193 0.023
embryonic placenta development GO:0001892 98 0.023
digestive system development GO:0055123 200 0.023
regulation of apoptotic signaling pathway GO:2001233 197 0.022
regulation of organelle organization GO:0033043 289 0.022
Mouse
embryonic epithelial tube formation GO:0001838 130 0.022
cellular protein catabolic process GO:0044257 155 0.022
ossification GO:0001503 216 0.022
regulation of cellular response to stress GO:0080135 159 0.022
Fly
digestive tract development GO:0048565 190 0.022
modification dependent protein catabolic process GO:0019941 133 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
cellular amine metabolic process GO:0044106 44 0.021
double strand break repair GO:0006302 48 0.021
appendage development GO:0048736 166 0.021
lymphocyte differentiation GO:0030098 242 0.021
methylation GO:0032259 134 0.021
Mouse
stem cell development GO:0048864 219 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
regulation of chromatin organization GO:1902275 57 0.021
Mouse
stem cell differentiation GO:0048863 268 0.021
negative regulation of chromatin modification GO:1903309 19 0.020
Mouse
circadian rhythm GO:0007623 114 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
Fly
regulation of histone methylation GO:0031060 30 0.020
Mouse
histone acetylation GO:0016573 41 0.020
cognition GO:0050890 149 0.020
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.020
regulation of neuron projection development GO:0010975 169 0.020
cellular lipid metabolic process GO:0044255 323 0.020
gene silencing by mirna GO:0035195 10 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
protein processing GO:0016485 163 0.020
response to light stimulus GO:0009416 135 0.020
dendrite development GO:0016358 115 0.019
regulation of multi organism process GO:0043900 111 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
epithelial tube formation GO:0072175 130 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
negative regulation of organelle organization GO:0010639 90 0.019
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.019
b cell activation GO:0042113 161 0.019
positive regulation of protein modification process GO:0031401 299 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
sensory organ morphogenesis GO:0090596 242 0.018
negative regulation of cell development GO:0010721 169 0.018
neuronal action potential GO:0019228 54 0.018
homeostasis of number of cells GO:0048872 210 0.018
neural tube formation GO:0001841 108 0.018
multicellular organismal signaling GO:0035637 91 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
positive regulation of defense response GO:0031349 124 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
regulation of hydrolase activity GO:0051336 246 0.018
histone h4 k16 acetylation GO:0043984 3 0.018
regulation of reactive oxygen species metabolic process GO:2000377 40 0.018
histone lysine demethylation GO:0070076 13 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
positive regulation of cell death GO:0010942 224 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.017
organelle localization GO:0051640 179 0.017
purine containing compound metabolic process GO:0072521 311 0.017
axonogenesis GO:0007409 274 0.017
regulation of response to wounding GO:1903034 189 0.017
regulation of innate immune response GO:0045088 91 0.017
internal peptidyl lysine acetylation GO:0018393 42 0.017
response to growth factor GO:0070848 198 0.017
regulation of cell cycle process GO:0010564 160 0.017
regulation of defense response GO:0031347 233 0.017
protein catabolic process GO:0030163 221 0.017
defense response to virus GO:0051607 68 0.017
t cell activation GO:0042110 289 0.017
learning or memory GO:0007611 148 0.017
peptidyl lysine acetylation GO:0018394 45 0.017
cell maturation GO:0048469 127 0.017
response to oxidative stress GO:0006979 123 0.016
regulation of inflammatory response GO:0050727 147 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
regulation of secretion GO:0051046 274 0.016
rna processing GO:0006396 105 0.016
regulation of neuron differentiation GO:0045664 281 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
regulation of cell size GO:0008361 72 0.016
protein deacylation GO:0035601 36 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.016
glucose homeostasis GO:0042593 128 0.016
response to uv GO:0009411 44 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.015
histone h4 acetylation GO:0043967 10 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
nucleoside catabolic process GO:0009164 206 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
skeletal system morphogenesis GO:0048705 203 0.015
regulation of membrane potential GO:0042391 192 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.015
nucleotide metabolic process GO:0009117 332 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
glial cell apoptotic process GO:0034349 3 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
limb morphogenesis GO:0035108 149 0.014
rho protein signal transduction GO:0007266 32 0.014
cell type specific apoptotic process GO:0097285 268 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
asymmetric stem cell division GO:0098722 3 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
negative regulation of axon extension GO:0030517 19 0.014
carbohydrate metabolic process GO:0005975 230 0.014
forebrain development GO:0030900 302 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
neural precursor cell proliferation GO:0061351 121 0.014
gene silencing by rna GO:0031047 19 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.013
gene silencing GO:0016458 38 0.013
Fly
purine ribonucleoside catabolic process GO:0046130 205 0.013
peptidyl lysine methylation GO:0018022 29 0.013
Mouse
response to oxygen levels GO:0070482 62 0.013
transcription from rna polymerase iii promoter GO:0006383 3 0.013
nucleobase containing small molecule metabolic process GO:0055086 352 0.013
asymmetric neuroblast division GO:0055059 1 0.013
innate immune response GO:0045087 157 0.013
regulation of kinase activity GO:0043549 249 0.013
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.013
intracellular receptor signaling pathway GO:0030522 74 0.013
inflammatory response GO:0006954 244 0.013
response to radiation GO:0009314 165 0.013
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.012
cytoplasmic transport GO:0016482 234 0.012
protein dealkylation GO:0008214 13 0.012
macromolecule deacylation GO:0098732 37 0.012
regulation of cell projection organization GO:0031344 206 0.012
dephosphorylation GO:0016311 129 0.012
gtp metabolic process GO:0046039 144 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
actin filament based movement GO:0030048 23 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
blastocyst formation GO:0001825 33 0.012
cytokine production GO:0001816 319 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
establishment or maintenance of cell polarity GO:0007163 86 0.012
histone deacetylation GO:0016575 26 0.012
neuron projection guidance GO:0097485 141 0.012
protein maturation GO:0051604 176 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
cellular response to peptide GO:1901653 92 0.012
action potential GO:0001508 78 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
signal transduction in absence of ligand GO:0038034 55 0.012
regulation of cell activation GO:0050865 289 0.012
mitotic cell cycle process GO:1903047 159 0.012
response to insulin GO:0032868 100 0.011
response to organonitrogen compound GO:0010243 246 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
chemotaxis GO:0006935 247 0.011
sensory perception of sound GO:0007605 97 0.011
response to extracellular stimulus GO:0009991 127 0.011
mrna processing GO:0006397 63 0.011
activation of immune response GO:0002253 138 0.011
regulation of ras gtpase activity GO:0032318 88 0.011
dna recombination GO:0006310 92 0.011
single organism cell adhesion GO:0098602 156 0.011
nucleoside metabolic process GO:0009116 246 0.011
regulation of system process GO:0044057 200 0.011
regulation of cell motility GO:2000145 236 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
defense response to other organism GO:0098542 197 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
regulation of mapk cascade GO:0043408 248 0.011
carbohydrate homeostasis GO:0033500 128 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
exocytosis GO:0006887 121 0.011
bone mineralization GO:0030282 54 0.011
protein targeting GO:0006605 143 0.011
learning GO:0007612 98 0.011
neural tube closure GO:0001843 90 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
sensory perception GO:0007600 245 0.011
regulation of transferase activity GO:0051338 263 0.011
dna methylation GO:0006306 43 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
establishment of tissue polarity GO:0007164 28 0.011
regulation of glucose metabolic process GO:0010906 60 0.011
regulation of cell migration GO:0030334 219 0.011
pharynx development GO:0060465 1 0.011
negative regulation of lymphocyte activation GO:0051250 91 0.010
blood circulation GO:0008015 195 0.010
regulation of cytokine production GO:0001817 266 0.010
negative regulation of immune system process GO:0002683 209 0.010
male gamete generation GO:0048232 285 0.010
Mouse
positive regulation of secretion by cell GO:1903532 114 0.010
regulation of protein transport GO:0051223 163 0.010
regulation of protein catabolic process GO:0042176 108 0.010
negative regulation of leukocyte proliferation GO:0070664 46 0.010
regulation of t cell activation GO:0050863 170 0.010
glycosyl compound metabolic process GO:1901657 246 0.010
adaptive immune response GO:0002250 155 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
primary neural tube formation GO:0014020 95 0.010
negative regulation of gene silencing GO:0060969 2 0.010
ribonucleoside triphosphate metabolic process GO:0009199 220 0.010
regulation of hormone levels GO:0010817 211 0.010
response to transforming growth factor beta GO:0071559 88 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
regulation of cellular response to growth factor stimulus GO:0090287 82 0.010
segmentation GO:0035282 93 0.010
regulation of cell cycle phase transition GO:1901987 77 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
b cell differentiation GO:0030183 78 0.010
posttranscriptional gene silencing GO:0016441 10 0.010

Kdm3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.022
disease of anatomical entity DOID:7 0 0.022
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012