|
|
regulation of pigment cell differentiation
|
GO:0050932 |
7 |
1.000
|
|
|
|
pigmentation
|
GO:0043473 |
71 |
1.000
|
|
|
|
melanocyte differentiation
|
GO:0030318 |
25 |
1.000
|
|
|
|
regulation of melanocyte differentiation
|
GO:0045634 |
7 |
1.000
|
|
|
|
pigment cell differentiation
|
GO:0050931 |
27 |
1.000
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.999
|
|
|
|
regulation of developmental pigmentation
|
GO:0048070 |
14 |
0.999
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.999
|
|
|
|
positive regulation of pigment cell differentiation
|
GO:0050942 |
5 |
0.999
|
|
|
|
positive regulation of developmental pigmentation
|
GO:0048087 |
6 |
0.998
|
|
|
|
positive regulation of melanocyte differentiation
|
GO:0045636 |
5 |
0.998
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.998
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:0097296 |
2 |
0.997
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.997
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.997
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.996
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.996
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.994
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.993
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.991
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.991
|
Mouse |
|
|
pigment metabolic process
|
GO:0042440 |
32 |
0.989
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.987
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.986
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.986
|
|
|
|
ectopic germ cell programmed cell death
|
GO:0035234 |
9 |
0.984
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.983
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
4 |
0.982
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.981
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.976
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.973
|
Mouse Fly |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.972
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.972
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.971
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.969
|
Human Mouse |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.968
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.968
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.968
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.967
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.965
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.956
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.952
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.944
|
Rat |
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.942
|
|
|
|
negative regulation of lymphocyte apoptotic process
|
GO:0070229 |
24 |
0.938
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.938
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.934
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
3 |
0.931
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.929
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.925
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.924
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.921
|
Human Mouse |
|
|
maintenance of location
|
GO:0051235 |
89 |
0.912
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.910
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.910
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.908
|
|
|
|
developmental pigmentation
|
GO:0048066 |
40 |
0.908
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.907
|
Mouse Fly |
|
|
hindbrain development
|
GO:0030902 |
128 |
0.900
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.895
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.894
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.891
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.889
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.889
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.884
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.883
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.882
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.876
|
Mouse |
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
4 |
0.873
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.871
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.866
|
|
|
|
cellular response to x ray
|
GO:0071481 |
2 |
0.864
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.864
|
Mouse |
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.864
|
Human Mouse Fly |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.863
|
Mouse |
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.862
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.860
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.859
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.852
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.850
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.846
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.845
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.844
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.843
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.841
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.835
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.827
|
Mouse |
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.824
|
Mouse |
|
|
phenol containing compound biosynthetic process
|
GO:0046189 |
21 |
0.820
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.819
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.813
|
Mouse |
|
|
embryonic hemopoiesis
|
GO:0035162 |
23 |
0.813
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.811
|
Mouse Fly |
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.811
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.810
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.801
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.792
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.789
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.786
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.782
|
Rat |
|
|
cation transport
|
GO:0006812 |
399 |
0.780
|
Mouse |
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.780
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.773
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001267 |
4 |
0.772
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.770
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.770
|
|
|
|
regulation of mast cell apoptotic process
|
GO:0033025 |
5 |
0.761
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.759
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.750
|
Zebrafish |
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.749
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.748
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.742
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.740
|
Human Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.731
|
Mouse Rat |
|
|
positive regulation of mast cell proliferation
|
GO:0070668 |
3 |
0.731
|
|
|
|
apoptotic process involved in mammary gland involution
|
GO:0060057 |
4 |
0.729
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.725
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.724
|
|
|
|
regulation of tissue remodeling
|
GO:0034103 |
38 |
0.724
|
Mouse |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.723
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.723
|
|
|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
5 |
0.721
|
|
|
|
regulation of myeloid cell apoptotic process
|
GO:0033032 |
19 |
0.720
|
|
|
|
formation of radial glial scaffolds
|
GO:0021943 |
4 |
0.718
|
|
|
|
neuroepithelial cell differentiation
|
GO:0060563 |
37 |
0.712
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.712
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.710
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.710
|
|
|
|
melanin metabolic process
|
GO:0006582 |
12 |
0.707
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.705
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.702
|
|
|
|
negative regulation of photoreceptor cell differentiation
|
GO:0046533 |
4 |
0.700
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
3 |
0.693
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.687
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.686
|
Mouse |
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.686
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.685
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.682
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.678
|
|
|
|
positive regulation of cell proliferation involved in heart valve morphogenesis
|
GO:0003251 |
1 |
0.671
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.668
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.666
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.660
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
26 |
0.656
|
Mouse |
|
|
response to x ray
|
GO:0010165 |
11 |
0.656
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.652
|
|
|
|
response to iron ion
|
GO:0010039 |
4 |
0.652
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.651
|
|
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
9 |
0.647
|
|
|
|
positive regulation of neuroepithelial cell differentiation
|
GO:1902913 |
5 |
0.644
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.642
|
Mouse Rat |
|
|
melanosome organization
|
GO:0032438 |
8 |
0.641
|
|
|
|
secondary metabolic process
|
GO:0019748 |
18 |
0.639
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.638
|
Mouse |
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.634
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.630
|
Mouse |
|
|
microtubule based process
|
GO:0007017 |
236 |
0.630
|
Fly |
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.628
|
|
|
|
alpha beta t cell lineage commitment
|
GO:0002363 |
7 |
0.626
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.623
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.622
|
Rat |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.619
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.614
|
Human Mouse |
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.614
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.612
|
Mouse |
|
|
organelle localization
|
GO:0051640 |
179 |
0.607
|
Human |
|
|
mast cell apoptotic process
|
GO:0033024 |
5 |
0.606
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
4 |
0.604
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.601
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.599
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.596
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.596
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c
|
GO:0008635 |
4 |
0.595
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.594
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
11 |
0.591
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.590
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.587
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.586
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.576
|
|
|
|
regulation of ph
|
GO:0006885 |
26 |
0.575
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
31 |
0.574
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.574
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
3 |
0.568
|
|
|
|
signal transduction involved in dna integrity checkpoint
|
GO:0072401 |
3 |
0.564
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.564
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.560
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.556
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.554
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
20 |
0.552
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.551
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.549
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.548
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.547
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.538
|
Mouse Rat |
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.532
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.532
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.531
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.530
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.530
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.529
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.529
|
Fly |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.529
|
Mouse |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.528
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.528
|
Human |
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
3 |
0.528
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
1 |
0.526
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
19 |
0.525
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.522
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.522
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.519
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.517
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
60 |
0.516
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.515
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.514
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.513
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.512
|
|
|
|
creatinine metabolic process
|
GO:0046449 |
3 |
0.510
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.507
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.506
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.503
|
Mouse |
|
|
regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0000083 |
3 |
0.502
|
|
|
|
photoreceptor cell morphogenesis
|
GO:0008594 |
3 |
0.501
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.501
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.501
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
59 |
0.494
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.493
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
41 |
0.492
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.491
|
|
|
|
negative regulation of mast cell apoptotic process
|
GO:0033026 |
4 |
0.489
|
|
|
|
pigment biosynthetic process
|
GO:0046148 |
26 |
0.487
|
|
|
|
succinate metabolic process
|
GO:0006105 |
4 |
0.487
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.486
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.484
|
Fly |
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.484
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.482
|
|
|
|
response to host
|
GO:0075136 |
3 |
0.478
|
|
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
4 |
0.478
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.477
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.477
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
18 |
0.476
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.475
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.475
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.474
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
26 |
0.470
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.468
|
Rat |
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
4 |
0.468
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.466
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.466
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.461
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
19 |
0.460
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.459
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.458
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.458
|
|
|
|
regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902108 |
14 |
0.457
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.456
|
Mouse |
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.454
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.454
|
|
|
|
taurine metabolic process
|
GO:0019530 |
4 |
0.452
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
11 |
0.447
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.447
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.444
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.443
|
|
|
|
cellular response to gamma radiation
|
GO:0071480 |
4 |
0.442
|
|
|
|
nitric oxide mediated signal transduction
|
GO:0007263 |
4 |
0.441
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.440
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.439
|
Human |
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
7 |
0.436
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.435
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.433
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.427
|
Mouse |
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.426
|
Mouse |
|
|
epithelium migration
|
GO:0090132 |
63 |
0.425
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.425
|
|
|
|
citrate metabolic process
|
GO:0006101 |
3 |
0.422
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.420
|
Mouse |
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.419
|
|
|
|
apoptotic process involved in embryonic digit morphogenesis
|
GO:1902263 |
3 |
0.414
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.412
|
Human |
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.411
|
|
|
|
mitochondrial outer membrane permeabilization involved in programmed cell death
|
GO:1902686 |
11 |
0.410
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.409
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.409
|
Mouse Rat |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.409
|
Mouse Rat |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.407
|
|
|
|
female gonad development
|
GO:0008585 |
71 |
0.403
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.402
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.401
|
Fly |
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.400
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.393
|
|
|
|
positive regulation of mitotic sister chromatid separation
|
GO:1901970 |
2 |
0.392
|
|
|
|
antral ovarian follicle growth
|
GO:0001547 |
5 |
0.392
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.392
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.392
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.389
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.389
|
|
|
|
negative regulation of phosphatidylinositol 3 kinase activity
|
GO:0043553 |
1 |
0.389
|
|
|
|
positive regulation of gene silencing by mirna
|
GO:2000637 |
1 |
0.387
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.385
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.384
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.384
|
Mouse |
|
|
male gonad development
|
GO:0008584 |
88 |
0.381
|
Human Mouse |
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.381
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.381
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
3 |
0.380
|
|
|
|
positive regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902110 |
11 |
0.379
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.378
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.378
|
Mouse Fly |
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.377
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.377
|
|
|
|
creatine metabolic process
|
GO:0006600 |
4 |
0.376
|
|
|
|
positive regulation of mammary gland involution
|
GO:1903521 |
4 |
0.374
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.374
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.373
|
|
|
|
histamine production involved in inflammatory response
|
GO:0002349 |
1 |
0.373
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.372
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
61 |
0.371
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.370
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.370
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.369
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001241 |
10 |
0.369
|
|
|
|
negative regulation of mammary gland epithelial cell proliferation
|
GO:0033600 |
3 |
0.369
|
|
|
|
regulation of t cell apoptotic process
|
GO:0070232 |
28 |
0.369
|
|
|
|
valine metabolic process
|
GO:0006573 |
4 |
0.364
|
|
|
|
regulation of isotype switching to ige isotypes
|
GO:0048293 |
7 |
0.363
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.359
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.356
|
|
|
|
positive regulation of natural killer cell activation
|
GO:0032816 |
15 |
0.352
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.351
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.350
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.350
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.350
|
Mouse |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.347
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.346
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.345
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.344
|
Mouse |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.342
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.342
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.341
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.341
|
Fly |
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.340
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.340
|
Mouse |
|
|
liver development
|
GO:0001889 |
66 |
0.337
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.336
|
Human Mouse |
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
9 |
0.336
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
63 |
0.335
|
|
|
|
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
|
GO:0001844 |
4 |
0.335
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.332
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.332
|
|
|
|
pigment granule organization
|
GO:0048753 |
9 |
0.331
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.330
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.329
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
4 |
0.329
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.326
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.326
|
|
|
|
epithelial cell differentiation involved in prostate gland development
|
GO:0060742 |
13 |
0.325
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
19 |
0.324
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.324
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.323
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.323
|
|
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
16 |
0.322
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.318
|
Mouse |
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.318
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.318
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.318
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.316
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
49 |
0.315
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.315
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.315
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.314
|
Mouse |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.313
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.312
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.312
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.312
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.310
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.309
|
|
|
|
positive regulation of isotype switching to ige isotypes
|
GO:0048295 |
4 |
0.309
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.309
|
|
|
|
cardiac muscle tissue growth
|
GO:0055017 |
37 |
0.308
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.307
|
|
|
|
negative regulation of osteoblast proliferation
|
GO:0033689 |
4 |
0.307
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.307
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.304
|
|
|
|
mast cell differentiation
|
GO:0060374 |
5 |
0.303
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.302
|
|
|
|
vasodilation
|
GO:0042311 |
28 |
0.301
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
14 |
0.301
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.299
|
Mouse |
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.299
|
Mouse |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.299
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.298
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.298
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
34 |
0.298
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
2 |
0.298
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.297
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.296
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.296
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.295
|
|
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
17 |
0.295
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.293
|
|
|
|
response to organophosphorus
|
GO:0046683 |
22 |
0.291
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.291
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.291
|
|
|
|
lysosome organization
|
GO:0007040 |
21 |
0.291
|
|
|
|
mast cell homeostasis
|
GO:0033023 |
5 |
0.290
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.290
|
|
|
|
b cell lineage commitment
|
GO:0002326 |
4 |
0.289
|
|
|
|
prostate gland growth
|
GO:0060736 |
13 |
0.287
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.286
|
Mouse Fly |
|
|
epithelial cell proliferation involved in prostate gland development
|
GO:0060767 |
11 |
0.286
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.282
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.281
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.281
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.279
|
|
|
|
positive regulation of mitotic metaphase anaphase transition
|
GO:0045842 |
2 |
0.279
|
|
|
|
regulation of cardiac cell fate specification
|
GO:2000043 |
1 |
0.279
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.279
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.277
|
|
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.277
|
|
|
|
stem cell division
|
GO:0017145 |
30 |
0.275
|
Rat |
|
|
positive regulation of lymphocyte apoptotic process
|
GO:0070230 |
13 |
0.275
|
|
|
|
regulation of b cell apoptotic process
|
GO:0002902 |
13 |
0.275
|
|
|
|
regulation of neuron migration
|
GO:2001222 |
22 |
0.274
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
4 |
0.273
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.269
|
Mouse |
|
|
allantoin metabolic process
|
GO:0000255 |
3 |
0.267
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.267
|
Mouse Fly |
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
3 |
0.267
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.266
|
Rat |
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.265
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.263
|
|
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
3 |
0.261
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.261
|
|
|
|
regulation of anoikis
|
GO:2000209 |
2 |
0.260
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.260
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.259
|
|
|
|
nephron tubule development
|
GO:0072080 |
84 |
0.259
|
|
|
|
foregut morphogenesis
|
GO:0007440 |
12 |
0.259
|
|
|
|
mitochondrial transport
|
GO:0006839 |
36 |
0.257
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.257
|
|
|
|
regulation of presynaptic membrane organization
|
GO:1901629 |
3 |
0.257
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.257
|
|
|
|
positive regulation of cgmp biosynthetic process
|
GO:0030828 |
6 |
0.256
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.255
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.255
|
|
|
|
mechanoreceptor differentiation
|
GO:0042490 |
67 |
0.255
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.254
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.253
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.253
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.253
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
63 |
0.252
|
|
|
|
viral process
|
GO:0016032 |
41 |
0.249
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.249
|
|
|
|
response to cholesterol
|
GO:0070723 |
4 |
0.248
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.248
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.247
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.246
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.246
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.245
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.243
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.243
|
Mouse |
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
13 |
0.242
|
|
|
|
neuron maturation
|
GO:0042551 |
29 |
0.240
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.240
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.239
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.239
|
Mouse |
|
|
vascular endothelial growth factor receptor signaling pathway
|
GO:0048010 |
24 |
0.239
|
Mouse |
|
|
positive regulation of microtubule polymerization
|
GO:0031116 |
3 |
0.235
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.234
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.234
|
|
|
|
prostate gland development
|
GO:0030850 |
48 |
0.234
|
|
|
|
negative regulation of fibroblast proliferation
|
GO:0048147 |
14 |
0.233
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.233
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.232
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.231
|
|
|
|
positive regulation of transcription by galactose
|
GO:0000411 |
1 |
0.230
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.230
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
29 |
0.229
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.228
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.227
|
Mouse |
|
|
response to interleukin 2
|
GO:0070669 |
2 |
0.223
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.222
|
|
|
|
cellular process regulating host cell cycle in response to virus
|
GO:0060154 |
3 |
0.222
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.222
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.222
|
|
