Mus musculus

0 known processes

Klk1

kallikrein 1

(Aliases: Kal,mGk-6,Klk6,Klk1b6,0610007D04Rik)

Klk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
kinin cascade GO:0002254 2 0.998
Mouse
negative regulation of neuron projection regeneration GO:0070571 3 0.990
Mouse
left ventricular cardiac muscle tissue morphogenesis GO:0003220 2 0.989
Mouse
tissue kallikrein kinin cascade GO:0002255 1 0.985
Mouse
positive regulation of lipid kinase activity GO:0090218 11 0.966
Mouse
protein activation cascade GO:0072376 19 0.964
Mouse
positive regulation of vasoconstriction GO:0045907 4 0.946
Rat
bradykinin biosynthetic process GO:0002936 1 0.944
Mouse
keratinocyte proliferation GO:0043616 21 0.888
Mouse
striated muscle contraction GO:0006941 45 0.835
Mouse
neuronal action potential GO:0019228 54 0.824
binding of sperm to zona pellucida GO:0007339 34 0.810
Mouse
brain renin angiotensin system GO:0002035 5 0.764
Mouse
phospholipid metabolic process GO:0006644 87 0.757
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.734
Mouse
regulation of myelination GO:0031641 20 0.707
Mouse
muscle system process GO:0003012 141 0.692
Mouse
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.679
Mouse
vasodilation GO:0042311 28 0.678
Mouse
inflammatory response GO:0006954 244 0.661
Mouse
cellular lipid metabolic process GO:0044255 323 0.656
Mouse
peptide metabolic process GO:0006518 46 0.642
Mouse
regulation of neuron projection regeneration GO:0070570 7 0.579
Mouse
action potential GO:0001508 78 0.569
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 11 0.567
Mouse
protein maturation GO:0051604 176 0.561
Mouse
protein processing GO:0016485 163 0.556
Mouse
multicellular organismal signaling GO:0035637 91 0.545
heart contraction GO:0060047 93 0.542
Mouse
cellular amide metabolic process GO:0043603 58 0.521
Mouse
peptide biosynthetic process GO:0043043 11 0.512
Mouse
heart process GO:0003015 94 0.509
Mouse
transmission of nerve impulse GO:0019226 76 0.505
regulation of blood volume by renin angiotensin GO:0002016 7 0.498
Mouse
regulation of transferase activity GO:0051338 263 0.492
Mouse
positive regulation of blood circulation GO:1903524 22 0.483
Rat
regulation of kinase activity GO:0043549 249 0.472
Mouse
cardiac muscle contraction GO:0060048 32 0.455
Mouse
regulation of membrane potential GO:0042391 192 0.450
small gtpase mediated signal transduction GO:0007264 97 0.437
Mouse
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.434
Mouse
zymogen activation GO:0031638 41 0.430
Mouse
cardiac ventricle development GO:0003231 83 0.419
Mouse
muscle contraction GO:0006936 101 0.391
Mouse
regulation of lipid kinase activity GO:0043550 14 0.386
Mouse
sperm egg recognition GO:0035036 37 0.383
Mouse
circulatory system process GO:0003013 197 0.373
Mouse Rat
ensheathment of neurons GO:0007272 76 0.371
Mouse
cardiac muscle tissue development GO:0048738 130 0.360
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.357
Mouse
extracellular matrix organization GO:0030198 147 0.353
Mouse
regulation of systemic arterial blood pressure GO:0003073 61 0.338
Mouse
positive regulation of kinase activity GO:0033674 155 0.336
Mouse
positive regulation of lipid metabolic process GO:0045834 40 0.334
Mouse
regulation of blood vessel size GO:0050880 56 0.313
Mouse Rat
vascular process in circulatory system GO:0003018 62 0.309
Mouse Rat
cell cell recognition GO:0009988 44 0.303
Mouse
heart morphogenesis GO:0003007 178 0.301
Mouse
axon regeneration GO:0031103 12 0.299
Mouse
myelination GO:0042552 74 0.295
Mouse
regulation of lipid metabolic process GO:0019216 118 0.286
Mouse
regulation of cellular response to stress GO:0080135 159 0.281
Mouse
muscle tissue development GO:0060537 308 0.281
Mouse
striated muscle tissue development GO:0014706 293 0.279
Mouse
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.268
Mouse
memory GO:0007613 58 0.257
Mouse
blood circulation GO:0008015 195 0.256
Mouse Rat
regulation of neuron projection development GO:0010975 169 0.246
Mouse
fertilization GO:0009566 127 0.244
Mouse
cardiac chamber development GO:0003205 108 0.244
Mouse
macromolecule catabolic process GO:0009057 281 0.241
Mouse
regulation of anatomical structure size GO:0090066 178 0.227
Mouse Rat
acute inflammatory response GO:0002526 41 0.224
Mouse
epithelial cell proliferation GO:0050673 174 0.215
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.209
Mouse
positive regulation of transferase activity GO:0051347 167 0.205
Mouse
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.205
Mouse
regulation of system process GO:0044057 200 0.205
Mouse Rat
endocrine process GO:0050886 39 0.200
Mouse
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 18 0.199
Mouse
neuron projection regeneration GO:0031102 14 0.198
Mouse
extracellular structure organization GO:0043062 148 0.197
Mouse
cardiac ventricle morphogenesis GO:0003208 50 0.197
Mouse
negative regulation of response to wounding GO:1903035 77 0.180
Mouse
cognition GO:0050890 149 0.176
Mouse
muscle tissue morphogenesis GO:0060415 53 0.168
Mouse
negative regulation of cell projection organization GO:0031345 56 0.163
Mouse
cellular amine metabolic process GO:0044106 44 0.162
regulation of blood pressure GO:0008217 93 0.158
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.154
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.150
ventricular cardiac muscle tissue development GO:0003229 38 0.150
Mouse
negative regulation of neuron projection development GO:0010977 50 0.149
Mouse
regulation of blood circulation GO:1903522 93 0.148
Rat
negative regulation of cell development GO:0010721 169 0.141
Mouse
cardiac left ventricle morphogenesis GO:0003214 9 0.140
Mouse
regulation of tube size GO:0035150 57 0.140
Mouse Rat
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.139
Mouse
negative regulation of cellular component organization GO:0051129 194 0.134
Mouse
regeneration GO:0031099 38 0.131
Mouse
vasoconstriction GO:0042310 27 0.129
Rat
aromatic compound catabolic process GO:0019439 286 0.119
synapse organization GO:0050808 125 0.117
Mouse
amine metabolic process GO:0009308 45 0.114
regulation of response to wounding GO:1903034 189 0.109
Mouse
amelogenesis GO:0097186 12 0.105
Mouse
cellular amino acid metabolic process GO:0006520 103 0.102
protein catabolic process GO:0030163 221 0.099
Mouse
carbohydrate homeostasis GO:0033500 128 0.099
regulation of neuron differentiation GO:0045664 281 0.095
Mouse
single fertilization GO:0007338 82 0.082
Mouse
cellular ketone metabolic process GO:0042180 84 0.082
regulation of neurological system process GO:0031644 22 0.081
Mouse
axon ensheathment GO:0008366 76 0.080
Mouse
regulation of cell projection organization GO:0031344 206 0.079
Mouse
cell recognition GO:0008037 83 0.073
Mouse
odontogenesis GO:0042476 78 0.073
Mouse
learning or memory GO:0007611 148 0.071
Mouse
regulation of vasoconstriction GO:0019229 14 0.071
Rat
glucose homeostasis GO:0042593 128 0.070
regulation of cellular ketone metabolic process GO:0010565 66 0.070
negative regulation of nervous system development GO:0051961 156 0.069
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.069
negative regulation of neurological system process GO:0031645 7 0.067
Mouse
response to extracellular stimulus GO:0009991 127 0.059
carbohydrate metabolic process GO:0005975 230 0.058
monocarboxylic acid metabolic process GO:0032787 191 0.055
amide transport GO:0042886 138 0.054
sodium ion transport GO:0006814 73 0.052
nucleobase containing small molecule metabolic process GO:0055086 352 0.051
amide biosynthetic process GO:0043604 16 0.051
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.050
cation transport GO:0006812 399 0.049
regulation of hormone levels GO:0010817 211 0.049
nucleoside triphosphate metabolic process GO:0009141 230 0.048
negative regulation of myelination GO:0031642 6 0.046
Mouse
nucleotide metabolic process GO:0009117 332 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
nitrogen compound transport GO:0071705 271 0.043
response to nutrient levels GO:0031667 109 0.042
glycerolipid metabolic process GO:0046486 122 0.042
Mouse
carboxylic acid biosynthetic process GO:0046394 86 0.042
cellular nitrogen compound catabolic process GO:0044270 280 0.042
negative regulation of molecular function GO:0044092 258 0.040
peptidyl amino acid modification GO:0018193 336 0.039
purine nucleoside triphosphate metabolic process GO:0009144 226 0.039
oxidation reduction process GO:0055114 342 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
purine nucleotide metabolic process GO:0006163 302 0.039
cellular homeostasis GO:0019725 240 0.039
negative regulation of cell proliferation GO:0008285 296 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
transmembrane transport GO:0055085 412 0.036
carbohydrate derivative biosynthetic process GO:1901137 183 0.036
nucleoside catabolic process GO:0009164 206 0.036
peptide transport GO:0015833 133 0.035
purine containing compound metabolic process GO:0072521 311 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.035
cellular chemical homeostasis GO:0055082 215 0.034
organic acid biosynthetic process GO:0016053 86 0.034
cellular biogenic amine metabolic process GO:0006576 28 0.033
interspecies interaction between organisms GO:0044419 83 0.031
heterocycle catabolic process GO:0046700 280 0.031
glycosyl compound metabolic process GO:1901657 246 0.031
cellular carbohydrate metabolic process GO:0044262 119 0.030
purine containing compound catabolic process GO:0072523 213 0.030
ribonucleoside catabolic process GO:0042454 206 0.030
hexose metabolic process GO:0019318 98 0.030
odontogenesis of dentin containing tooth GO:0042475 66 0.029
Mouse
second messenger mediated signaling GO:0019932 73 0.029
lipid homeostasis GO:0055088 63 0.028
inorganic cation transmembrane transport GO:0098662 207 0.028
positive regulation of programmed cell death GO:0043068 218 0.028
anion transport GO:0006820 177 0.027
regulation of hydrolase activity GO:0051336 246 0.027
regulation of body fluid levels GO:0050878 162 0.027
ribonucleoside metabolic process GO:0009119 245 0.027
cell adhesion GO:0007155 329 0.027
response to organonitrogen compound GO:0010243 246 0.027
glycosyl compound catabolic process GO:1901658 206 0.026
defense response to other organism GO:0098542 197 0.026
regulation of peptide secretion GO:0002791 77 0.026
ion transmembrane transport GO:0034220 361 0.026
divalent metal ion transport GO:0070838 172 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
dephosphorylation GO:0016311 129 0.025
regulation of epithelial cell proliferation GO:0050678 141 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.024
nucleoside metabolic process GO:0009116 246 0.024
skin development GO:0043588 220 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
alpha amino acid metabolic process GO:1901605 59 0.024
synaptic transmission GO:0007268 329 0.024
Mouse
nucleotide catabolic process GO:0009166 217 0.023
cholesterol homeostasis GO:0042632 44 0.023
negative regulation of protein modification process GO:0031400 163 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
divalent inorganic cation homeostasis GO:0072507 138 0.021
digestion GO:0007586 40 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.020
regulation of endopeptidase activity GO:0052548 89 0.020
sterol homeostasis GO:0055092 45 0.020
multicellular organism growth GO:0035264 161 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
male gamete generation GO:0048232 285 0.019
peptide secretion GO:0002790 114 0.019
neutral lipid metabolic process GO:0006638 57 0.019
regulation of protein serine threonine kinase activity GO:0071900 157 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
negative regulation of phagocytosis GO:0050765 4 0.019
multicellular organismal water homeostasis GO:0050891 23 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
cellular metal ion homeostasis GO:0006875 151 0.019
hormone metabolic process GO:0042445 86 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
organic anion transport GO:0015711 137 0.018
sensory perception GO:0007600 245 0.018
cellular response to extracellular stimulus GO:0031668 81 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
fatty acid metabolic process GO:0006631 121 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
response to light stimulus GO:0009416 135 0.018
locomotory behavior GO:0007626 195 0.018
positive regulation of cell death GO:0010942 224 0.018
cation transmembrane transport GO:0098655 266 0.018
rho protein signal transduction GO:0007266 32 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
regulation of cell activation GO:0050865 289 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
cellular response to peptide hormone stimulus GO:0071375 92 0.017
monocarboxylic acid biosynthetic process GO:0072330 61 0.017
calcium mediated signaling GO:0019722 46 0.017
negative regulation of immune system process GO:0002683 209 0.017
tissue homeostasis GO:0001894 115 0.017
cellular response to starvation GO:0009267 57 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
regulation of intracellular transport GO:0032386 159 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
chromatin modification GO:0016568 187 0.017
epithelial cell development GO:0002064 159 0.016
regulation of peptide hormone secretion GO:0090276 75 0.016
response to organic cyclic compound GO:0014070 198 0.016
regulation of metal ion transport GO:0010959 106 0.016
maintenance of location GO:0051235 89 0.016
regulation of cell cycle GO:0051726 281 0.016
membrane lipid metabolic process GO:0006643 53 0.016
blood vessel morphogenesis GO:0048514 285 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
small molecule catabolic process GO:0044282 71 0.016
defense response to bacterium GO:0042742 119 0.016
organic acid transport GO:0015849 101 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
fat cell differentiation GO:0045444 160 0.015
regulation of ion transport GO:0043269 215 0.015
glycoprotein metabolic process GO:0009100 116 0.015
response to acid chemical GO:0001101 111 0.015
organophosphate catabolic process GO:0046434 232 0.015
cellular response to external stimulus GO:0071496 88 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
response to starvation GO:0042594 65 0.015
leukocyte chemotaxis GO:0030595 69 0.015
protein glycosylation GO:0006486 55 0.015
ribonucleotide catabolic process GO:0009261 208 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
generation of precursor metabolites and energy GO:0006091 103 0.014
steroid metabolic process GO:0008202 119 0.014
cell junction organization GO:0034330 77 0.014
lipid biosynthetic process GO:0008610 179 0.014
cdc42 protein signal transduction GO:0032488 0 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
chemotaxis GO:0006935 247 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
organic acid catabolic process GO:0016054 51 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.014
peptide hormone secretion GO:0030072 109 0.014
response to radiation GO:0009314 165 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
wound healing GO:0042060 157 0.013
positive regulation of ion transport GO:0043270 65 0.013
leukocyte migration GO:0050900 124 0.013
regulation of cytokine production GO:0001817 266 0.013
regulation of water loss via skin GO:0033561 16 0.013
pancreas morphogenesis GO:0061113 3 0.013
regulation of organelle organization GO:0033043 289 0.013
anatomical structure homeostasis GO:0060249 145 0.013
histone modification GO:0016570 159 0.013
pancreas development GO:0031016 57 0.013
intracellular protein transport GO:0006886 204 0.013
divalent inorganic cation transport GO:0072511 178 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
gland development GO:0048732 330 0.013
exocrine pancreas development GO:0031017 7 0.013
ear development GO:0043583 200 0.013
learning GO:0007612 98 0.013
negative regulation of serine type endopeptidase activity GO:1900004 2 0.013
membrane organization GO:0061024 245 0.013
ras protein signal transduction GO:0007265 77 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
regulation of serine type endopeptidase activity GO:1900003 2 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
cytokine production GO:0001816 319 0.013
sequestering of metal ion GO:0051238 19 0.013
lipoprotein metabolic process GO:0042157 43 0.012
cellular response to lipid GO:0071396 145 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
hormone secretion GO:0046879 128 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
endocytosis GO:0006897 168 0.012
cell cell junction organization GO:0045216 72 0.012
circadian rhythm GO:0007623 114 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.012
protein oligomerization GO:0051259 67 0.012
cellular response to steroid hormone stimulus GO:0071383 33 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
mitotic cell cycle GO:0000278 195 0.012
sequestering of calcium ion GO:0051208 18 0.012
cellular amino acid catabolic process GO:0009063 25 0.012
regulation of cell motility GO:2000145 236 0.012
monosaccharide metabolic process GO:0005996 106 0.012
progesterone metabolic process GO:0042448 4 0.012
diacylglycerol biosynthetic process GO:0006651 2 0.012
single organismal cell cell adhesion GO:0016337 131 0.012
acid secretion GO:0046717 33 0.012
lipid localization GO:0010876 126 0.011
meiotic cell cycle process GO:1903046 77 0.011
adaptive immune response GO:0002250 155 0.011
lymphocyte proliferation GO:0046651 164 0.011
alpha amino acid biosynthetic process GO:1901607 15 0.011
glycosylation GO:0070085 62 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
acylglycerol metabolic process GO:0006639 55 0.011
cell chemotaxis GO:0060326 81 0.011
leukocyte proliferation GO:0070661 172 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
regulation of proteolysis GO:0030162 164 0.011
rna processing GO:0006396 105 0.011
covalent chromatin modification GO:0016569 163 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
leukocyte mediated immunity GO:0002443 174 0.011
protein methylation GO:0006479 81 0.011
mrna metabolic process GO:0016071 84 0.011
regulation of hormone secretion GO:0046883 88 0.011
rna catabolic process GO:0006401 29 0.011
regulation of transmembrane transport GO:0034762 128 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
glucose metabolic process GO:0006006 92 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
cytoplasmic transport GO:0016482 234 0.011
regulation of cell cycle process GO:0010564 160 0.011
regulation of ras gtpase activity GO:0032318 88 0.011
spermatid development GO:0007286 108 0.011
regulation of secretion by cell GO:1903530 249 0.010
cell type specific apoptotic process GO:0097285 268 0.010
proton transport GO:0015992 35 0.010
myeloid leukocyte migration GO:0097529 57 0.010
organic hydroxy compound transport GO:0015850 93 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
regulation of defense response GO:0031347 233 0.010
calcium ion transport GO:0006816 159 0.010
protein homooligomerization GO:0051260 43 0.010
blastocyst development GO:0001824 80 0.010
immune effector process GO:0002252 321 0.010
protein targeting GO:0006605 143 0.010
regulation of carbohydrate metabolic process GO:0006109 75 0.010
ossification GO:0001503 216 0.010
regulation of peptidase activity GO:0052547 96 0.010
alcohol metabolic process GO:0006066 116 0.010
sulfur compound metabolic process GO:0006790 100 0.010
regulation of secretion GO:0051046 274 0.010
insulin secretion GO:0030073 89 0.010
developmental maturation GO:0021700 193 0.010
regulation of angiotensin levels in blood GO:0002002 4 0.010

Klk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.023
disease of anatomical entity DOID:7 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
nervous system disease DOID:863 0 0.011
inherited metabolic disorder DOID:655 0 0.011