Mus musculus

32 known processes

Klk4

kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)

(Aliases: PSTS,KLK-L1,ESMP1,Prss17)

Klk4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ossification GO:0001503 216 0.599
neural precursor cell proliferation GO:0061351 121 0.533
forebrain development GO:0030900 302 0.445
somatotropin secreting cell differentiation GO:0060126 4 0.426
tissue remodeling GO:0048771 102 0.400
paraxial mesodermal cell fate commitment GO:0048343 2 0.346
regulation of blood pressure GO:0008217 93 0.346
Mouse
transmembrane transport GO:0055085 412 0.326
organic hydroxy compound transport GO:0015850 93 0.319
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.317
regulation of angiogenesis GO:0045765 81 0.304
placenta development GO:0001890 140 0.298
polarity specification of proximal distal axis GO:0010085 2 0.297
circulatory system process GO:0003013 197 0.281
Mouse
amine metabolic process GO:0009308 45 0.278
cytokine production GO:0001816 319 0.274
nitrogen compound transport GO:0071705 271 0.255
stem cell proliferation GO:0072089 117 0.253
regulation of secretion GO:0051046 274 0.251
paraxial mesodermal cell differentiation GO:0048342 2 0.246
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.244
g protein coupled receptor signaling pathway GO:0007186 243 0.236
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.234
embryonic placenta development GO:0001892 98 0.234
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.231
central nervous system neuron differentiation GO:0021953 162 0.231
ion transmembrane transport GO:0034220 361 0.222
cytosolic calcium ion homeostasis GO:0051480 70 0.206
angiogenesis GO:0001525 201 0.204
calcium ion transport GO:0006816 159 0.201
gland development GO:0048732 330 0.200
multicellular organismal homeostasis GO:0048871 164 0.198
regulation of cytokine production GO:0001817 266 0.189
ameboidal type cell migration GO:0001667 128 0.180
rhythmic process GO:0048511 174 0.177
cellular amino acid metabolic process GO:0006520 103 0.174
blood circulation GO:0008015 195 0.172
Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.170
conditioned taste aversion GO:0001661 4 0.169
cellular homeostasis GO:0019725 240 0.168
multicellular organism growth GO:0035264 161 0.160
central nervous system neuron development GO:0021954 67 0.159
blood vessel morphogenesis GO:0048514 285 0.159
positive regulation of angiogenesis GO:0045766 46 0.156
regulation of membrane potential GO:0042391 192 0.155
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.154
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.153
regulation of cell cycle GO:0051726 281 0.153
nucleoside phosphate biosynthetic process GO:1901293 79 0.152
regulation of transferase activity GO:0051338 263 0.150
Mouse
metanephric loop of henle development GO:0072236 4 0.146
ectoderm formation GO:0001705 3 0.140
positive regulation of lymphocyte activation GO:0051251 140 0.140
positive regulation of nervous system development GO:0051962 221 0.138
cellular amine metabolic process GO:0044106 44 0.138
protein secretion GO:0009306 111 0.137
histamine induced gastric acid secretion GO:0001697 1 0.134
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.131
organic hydroxy compound metabolic process GO:1901615 203 0.128
regulation of secretion by cell GO:1903530 249 0.124
positive regulation of cell development GO:0010720 237 0.122
adenohypophysis development GO:0021984 14 0.120
cellular ketone metabolic process GO:0042180 84 0.120
cell division GO:0051301 120 0.119
regulation of cell motility GO:2000145 236 0.118
pituitary gland development GO:0021983 38 0.115
somatotropin secreting cell development GO:0060133 2 0.113
regulation of cellular ketone metabolic process GO:0010565 66 0.112
regulation of cell division GO:0051302 76 0.111
forebrain neuron development GO:0021884 30 0.111
response to nutrient levels GO:0031667 109 0.111
cellular divalent inorganic cation homeostasis GO:0072503 127 0.111
oviduct development GO:0060066 3 0.110
b cell activation GO:0042113 161 0.109
cell maturation GO:0048469 127 0.108
skin development GO:0043588 220 0.107
skeletal system development GO:0001501 356 0.106
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.106
regulation of ossification GO:0030278 112 0.106
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.105
renal tubule development GO:0061326 87 0.105
forebrain cell migration GO:0021885 58 0.104
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.104
Mouse
regulation of anagen GO:0051884 1 0.104
striated muscle tissue development GO:0014706 293 0.103
Mouse
cation transport GO:0006812 399 0.103
gastrin induced gastric acid secretion GO:0001698 1 0.101
lung induction GO:0060492 3 0.101
renal inner medulla development GO:0072053 3 0.101
positive regulation of cell motility GO:2000147 116 0.100
learning or memory GO:0007611 148 0.099
Mouse
spinal cord development GO:0021510 81 0.099
regulation of cell migration GO:0030334 219 0.099
lipid transport GO:0006869 98 0.098
circadian sleep wake cycle rem sleep GO:0042747 1 0.098
embryonic organ morphogenesis GO:0048562 276 0.097
leukocyte proliferation GO:0070661 172 0.095
chemotaxis GO:0006935 247 0.093
odontogenesis of dentin containing tooth GO:0042475 66 0.093
response to extracellular stimulus GO:0009991 127 0.092
cellular ion homeostasis GO:0006873 165 0.092
organonitrogen compound biosynthetic process GO:1901566 192 0.090
Mouse
synaptic transmission GO:0007268 329 0.090
Mouse
positive regulation of stem cell proliferation GO:2000648 59 0.089
auditory receptor cell fate specification GO:0042667 1 0.088
negative regulation of cell proliferation GO:0008285 296 0.086
ribose phosphate biosynthetic process GO:0046390 59 0.086
cellular metal ion homeostasis GO:0006875 151 0.086
chromatin modification GO:0016568 187 0.085
calcium ion homeostasis GO:0055074 127 0.084
regulation of nucleotide metabolic process GO:0006140 169 0.084
regulation of renal sodium excretion GO:0035813 3 0.083
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.083
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.082
positive regulation of cell death GO:0010942 224 0.082
myeloid cell differentiation GO:0030099 233 0.081
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.081
regulation of neuroblast proliferation GO:1902692 27 0.080
metal ion homeostasis GO:0055065 189 0.080
forebrain morphogenesis GO:0048853 17 0.080
locomotory behavior GO:0007626 195 0.080
tendon formation GO:0035992 4 0.079
limb development GO:0060173 166 0.079
g protein coupled receptor internalization GO:0002031 3 0.079
divalent metal ion transport GO:0070838 172 0.077
appendage development GO:0048736 166 0.077
leukocyte migration GO:0050900 124 0.076
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.076
regulation of camp metabolic process GO:0030814 30 0.076
negative regulation of prostatic bud formation GO:0060686 4 0.076
cognition GO:0050890 149 0.076
Mouse
phospholipid metabolic process GO:0006644 87 0.075
Mouse
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.075
camera type eye development GO:0043010 266 0.075
regulation of camp biosynthetic process GO:0030817 25 0.074
anion transport GO:0006820 177 0.074
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.073
biomineral tissue development GO:0031214 64 0.072
lymphocyte proliferation GO:0046651 164 0.072
nucleoside phosphate metabolic process GO:0006753 338 0.071
positive regulation of secretion by cell GO:1903532 114 0.070
epithelial tube morphogenesis GO:0060562 303 0.070
epithelial cell development GO:0002064 159 0.069
positive regulation of camp metabolic process GO:0030816 19 0.068
regulation of hormone secretion GO:0046883 88 0.067
subpallium neuron fate commitment GO:0060163 2 0.067
hypophysis morphogenesis GO:0048850 3 0.067
positive regulation of growth hormone secretion GO:0060124 3 0.067
negative regulation of neuron death GO:1901215 98 0.066
developmental maturation GO:0021700 193 0.066
epithelial cell proliferation GO:0050673 174 0.066
Mouse
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.066
metencephalon development GO:0022037 89 0.066
positive regulation of cytokine production GO:0001819 174 0.066
cellular response to temperature stimulus GO:0071502 2 0.065
purine ribonucleotide biosynthetic process GO:0009152 59 0.065
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.065
kidney epithelium development GO:0072073 121 0.064
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.063
inner medullary collecting duct development GO:0072061 2 0.063
regulation of hormone levels GO:0010817 211 0.062
embryonic appendage morphogenesis GO:0035113 126 0.062
mesoderm development GO:0007498 100 0.061
negative regulation of angiogenesis GO:0016525 25 0.061
regulation of ion transport GO:0043269 215 0.061
positive regulation of lymphocyte proliferation GO:0050671 70 0.061
forebrain generation of neurons GO:0021872 63 0.061
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.060
hippocampus development GO:0021766 52 0.060
purine nucleotide biosynthetic process GO:0006164 65 0.059
cell fate commitment GO:0045165 210 0.059
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 3 0.059
ribonucleotide metabolic process GO:0009259 291 0.059
regulation of ion homeostasis GO:2000021 64 0.058
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.058
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.058
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.058
cell proliferation in forebrain GO:0021846 30 0.057
female sex differentiation GO:0046660 84 0.057
camp biosynthetic process GO:0006171 31 0.057
bone resorption GO:0045453 38 0.057
sensory perception of light stimulus GO:0050953 54 0.057
cation homeostasis GO:0055080 212 0.056
renal sodium excretion GO:0035812 3 0.055
response to organonitrogen compound GO:0010243 246 0.055
leukocyte differentiation GO:0002521 342 0.055
activation of adenylate cyclase activity GO:0007190 4 0.055
germ cell development GO:0007281 185 0.054
paramesonephric duct development GO:0061205 3 0.054
synaptic transmission involved in micturition GO:0060084 3 0.054
pyramidal neuron migration GO:0021852 1 0.054
ribonucleotide biosynthetic process GO:0009260 59 0.053
establishment of organ orientation GO:0048561 1 0.053
neurohypophysis development GO:0021985 2 0.053
positive regulation of secretion GO:0051047 130 0.053
cardiac cell fate determination GO:0060913 2 0.052
b cell proliferation GO:0042100 53 0.052
branching morphogenesis of an epithelial tube GO:0048754 159 0.052
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.051
wnt signaling pathway GO:0016055 188 0.051
oxidation reduction process GO:0055114 342 0.051
extracellular matrix organization GO:0030198 147 0.051
cyclic nucleotide metabolic process GO:0009187 59 0.051
regulation of cellular amino acid metabolic process GO:0006521 5 0.050
mesoderm morphogenesis GO:0048332 64 0.050
organic hydroxy compound biosynthetic process GO:1901617 77 0.050
positive regulation of growth GO:0045927 104 0.050
cell type specific apoptotic process GO:0097285 268 0.050
cation transmembrane transport GO:0098655 266 0.050
olfactory learning GO:0008355 2 0.049
ear morphogenesis GO:0042471 118 0.049
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.049
embryonic limb morphogenesis GO:0030326 126 0.048
osteoclast differentiation GO:0030316 62 0.048
inflammatory response GO:0006954 244 0.048
Mouse
regulation of establishment of protein localization GO:0070201 181 0.048
morphogenesis of a branching epithelium GO:0061138 193 0.048
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.048
epithelial mesenchymal signaling involved in prostate gland development GO:0060738 2 0.047
hair follicle development GO:0001942 85 0.047
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.047
appendage morphogenesis GO:0035107 149 0.047
metanephros development GO:0001656 79 0.047
carboxylic acid transport GO:0046942 100 0.047
inorganic ion transmembrane transport GO:0098660 234 0.047
positive regulation of blood pressure GO:0045777 21 0.047
endocrine process GO:0050886 39 0.047
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 42 0.047
pallium development GO:0021543 120 0.047
diencephalon development GO:0021536 63 0.046
nucleotide biosynthetic process GO:0009165 78 0.046
axis elongation involved in somitogenesis GO:0090245 4 0.046
sperm motility GO:0030317 47 0.046
nephron epithelium morphogenesis GO:0072088 68 0.046
ovulation cycle GO:0042698 59 0.046
regulation of reproductive process GO:2000241 66 0.046
cell activation involved in immune response GO:0002263 126 0.046
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.046
nucleobase containing small molecule metabolic process GO:0055086 352 0.046
regulation of vasculature development GO:1901342 88 0.045
regulation of protein transport GO:0051223 163 0.045
limb morphogenesis GO:0035108 149 0.045
digestive system development GO:0055123 200 0.045
limbic system development GO:0021761 72 0.045
ureteric bud morphogenesis GO:0060675 62 0.045
peptidyl tyrosine phosphorylation GO:0018108 143 0.045
ear development GO:0043583 200 0.044
nuclear import GO:0051170 95 0.044
female gonad development GO:0008585 71 0.044
positive regulation of camp mediated signaling GO:0043950 3 0.044
regulation of serotonin secretion GO:0014062 3 0.044
regulation of lymphocyte proliferation GO:0050670 117 0.043
metanephric capsule morphogenesis GO:0072265 1 0.043
negative regulation of response to wounding GO:1903035 77 0.043
Mouse
kidney morphogenesis GO:0060993 83 0.043
mesonephric tubule development GO:0072164 94 0.043
carbohydrate metabolic process GO:0005975 230 0.043
glomerular mesangial cell development GO:0072144 3 0.043
digestive tract development GO:0048565 190 0.042
positive regulation of ossification GO:0045778 47 0.042
muscle tissue development GO:0060537 308 0.042
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.042
cervix development GO:0060067 2 0.042
positive regulation of cytokine biosynthetic process GO:0042108 40 0.042
regulation of organelle organization GO:0033043 289 0.042
bmp signaling pathway GO:0030509 93 0.042
neural tube development GO:0021915 160 0.041
regulation of homeostatic process GO:0032844 182 0.041
general adaptation syndrome GO:0051866 2 0.041
cell differentiation in spinal cord GO:0021515 53 0.041
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.041
mesoderm formation GO:0001707 62 0.041
positive regulation of programmed cell death GO:0043068 218 0.041
skeletal system morphogenesis GO:0048705 203 0.040
sensory system development GO:0048880 3 0.040
generation of precursor metabolites and energy GO:0006091 103 0.040
fat cell differentiation GO:0045444 160 0.040
urogenital system development GO:0001655 261 0.040
mitotic cell cycle GO:0000278 195 0.040
sprouting angiogenesis GO:0002040 26 0.040
prostate gland stromal morphogenesis GO:0060741 2 0.040
hormone secretion GO:0046879 128 0.040
small molecule biosynthetic process GO:0044283 132 0.040
positive regulation of camp biosynthetic process GO:0030819 19 0.040
positive regulation of the force of heart contraction by chemical signal GO:0003099 3 0.039
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.039
metanephric thick ascending limb development GO:0072233 2 0.039
organic anion transport GO:0015711 137 0.039
kidney development GO:0001822 213 0.039
monoamine transport GO:0015844 33 0.039
negative regulation of molecular function GO:0044092 258 0.039
protein ubiquitination GO:0016567 171 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.039
hair follicle morphogenesis GO:0031069 29 0.039
neuroblast proliferation GO:0007405 49 0.039
renal capsule specification GO:0072130 1 0.039
stem cell differentiation GO:0048863 268 0.039
trachea cartilage morphogenesis GO:0060535 4 0.039
corticosterone secretion GO:0035934 3 0.038
metanephric capsule specification GO:0072267 1 0.038
peptidyl amino acid modification GO:0018193 336 0.038
central nervous system vasculogenesis GO:0022009 3 0.038
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.038
testosterone biosynthetic process GO:0061370 2 0.038
positive regulation of nucleotide metabolic process GO:0045981 114 0.038
phenol containing compound metabolic process GO:0018958 60 0.038
extracellular structure organization GO:0043062 148 0.038
spemann organizer formation GO:0060061 2 0.037
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.037
cytoplasmic transport GO:0016482 234 0.037
nephron tubule morphogenesis GO:0072078 68 0.037
divalent inorganic cation homeostasis GO:0072507 138 0.037
regulation of carbohydrate metabolic process GO:0006109 75 0.037
blastocyst development GO:0001824 80 0.037
myeloid leukocyte differentiation GO:0002573 119 0.037
sensory organ morphogenesis GO:0090596 242 0.037
regulation of system process GO:0044057 200 0.037
Mouse
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.037
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.037
dopaminergic neuron differentiation GO:0071542 14 0.037
regulation of lymphocyte activation GO:0051249 240 0.036
renal capsule morphogenesis GO:0072128 1 0.036
cellular modified amino acid metabolic process GO:0006575 63 0.036
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.036
positive regulation of epithelial cell proliferation GO:0050679 68 0.036
fear response GO:0042596 33 0.036
negative regulation of cell activation GO:0050866 111 0.036
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.036
cell chemotaxis GO:0060326 81 0.036
regulation of stem cell differentiation GO:2000736 50 0.036
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.036
cyclic nucleotide biosynthetic process GO:0009190 44 0.035
sodium ion transport GO:0006814 73 0.035
cochlea morphogenesis GO:0090103 22 0.035
mesonephric duct formation GO:0072181 2 0.035
regulation of purine nucleotide metabolic process GO:1900542 169 0.035
renal system process GO:0003014 48 0.035
collagen fibril organization GO:0030199 32 0.035
nephrogenic mesenchyme development GO:0072076 3 0.035
bone development GO:0060348 120 0.035
regulation of multi organism process GO:0043900 111 0.035
wound healing GO:0042060 157 0.035
positive regulation of leukocyte proliferation GO:0070665 73 0.035
response to molecule of bacterial origin GO:0002237 143 0.035
purine containing compound metabolic process GO:0072521 311 0.035
cerebral cortex cell migration GO:0021795 44 0.034
substrate independent telencephalic tangential migration GO:0021826 8 0.034
calcium mediated signaling GO:0019722 46 0.034
response to organic cyclic compound GO:0014070 198 0.034
cellular response to extracellular stimulus GO:0031668 81 0.034
regulation of synaptic plasticity GO:0048167 87 0.034
negative regulation of neuron apoptotic process GO:0043524 92 0.034
cytokine metabolic process GO:0042107 71 0.034
cell differentiation involved in embryonic placenta development GO:0060706 26 0.034
hindbrain morphogenesis GO:0021575 46 0.034
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.034
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.034
regulation of neuron differentiation GO:0045664 281 0.034
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.034
neuroblast differentiation GO:0014016 2 0.033
regulation of response to wounding GO:1903034 189 0.033
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.033
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.033
spermatogenesis GO:0007283 284 0.033
kidney rudiment formation GO:0072003 3 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.033
positive regulation of cell division GO:0051781 31 0.033
telencephalon cell migration GO:0022029 55 0.033
multi multicellular organism process GO:0044706 109 0.033
formation of primary germ layer GO:0001704 77 0.033
negative regulation of vasculature development GO:1901343 26 0.033
negative regulation of adenylate cyclase activity GO:0007194 1 0.033
cellular response to hormone stimulus GO:0032870 150 0.033
cardiac right atrium morphogenesis GO:0003213 3 0.033
chromatin organization GO:0006325 206 0.033
regulation of bmp signaling pathway GO:0030510 60 0.033
tissue homeostasis GO:0001894 115 0.033
neuroepithelial cell differentiation GO:0060563 37 0.033
muscle contraction GO:0006936 101 0.033
Mouse
axial mesoderm formation GO:0048320 3 0.032
positive regulation of cell migration GO:0030335 109 0.032
embryonic skeletal system morphogenesis GO:0048704 91 0.032
central nervous system morphogenesis GO:0021551 2 0.032
neuron death GO:0070997 154 0.032
bone remodeling GO:0046849 53 0.032
regulation of organ morphogenesis GO:2000027 144 0.032
prostate gland development GO:0030850 48 0.032
positive regulation of protein modification process GO:0031401 299 0.032
renal capsule formation GO:0072129 1 0.032
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.032
foregut regionalization GO:0060423 3 0.032
hair cycle GO:0042633 90 0.031
cerebellum formation GO:0021588 1 0.031
regulation of nucleotide biosynthetic process GO:0030808 34 0.031
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.031
mitotic cell cycle process GO:1903047 159 0.031
regulation of action potential GO:0098900 4 0.031
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.031
regulation of osteoblast differentiation GO:0045667 67 0.031
exocrine system development GO:0035272 45 0.030
mesonephric tubule morphogenesis GO:0072171 63 0.030
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.030
neural tube patterning GO:0021532 43 0.030
regulation of protein localization GO:0032880 231 0.030
nephron epithelium development GO:0072009 92 0.030
development of primary female sexual characteristics GO:0046545 73 0.030
positive regulation of apoptotic process GO:0043065 217 0.030
pancreatic pp cell fate commitment GO:0003329 2 0.030
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.030
response to starvation GO:0042594 65 0.030
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.030
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.029
cerebral cortex development GO:0021987 86 0.029
embryonic heart tube development GO:0035050 65 0.029
chondrocyte differentiation GO:0002062 72 0.029
second messenger mediated signaling GO:0019932 73 0.029
toxin transport GO:1901998 38 0.029
negative regulation of blood vessel morphogenesis GO:2000181 25 0.029
nephron development GO:0072006 109 0.029
cellular chemical homeostasis GO:0055082 215 0.029
ureteric bud development GO:0001657 94 0.029
stem cell development GO:0048864 219 0.029
stem cell fate determination GO:0048867 2 0.029
regulation of kinase activity GO:0043549 249 0.029
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.028
antigen receptor mediated signaling pathway GO:0050851 64 0.028
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.028
female somatic sex determination GO:0019101 1 0.028
acid secretion GO:0046717 33 0.028
spinal cord motor neuron cell fate specification GO:0021520 13 0.028
lung field specification GO:0060424 3 0.028
camp metabolic process GO:0046058 40 0.028
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.028
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.028
regulation of circadian sleep wake cycle GO:0042749 3 0.028
carbohydrate derivative biosynthetic process GO:1901137 183 0.028
odontogenesis GO:0042476 78 0.028
tumor necrosis factor production GO:0032640 50 0.028
transmission of nerve impulse GO:0019226 76 0.028
neuron neuron synaptic transmission GO:0007270 69 0.028
pancreatic a cell fate commitment GO:0003326 2 0.028
regulation of blood circulation GO:1903522 93 0.028
lipid localization GO:0010876 126 0.028
nephron morphogenesis GO:0072028 69 0.028
regulation of peptide hormone secretion GO:0090276 75 0.027
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.027
cellular response to external stimulus GO:0071496 88 0.027
embryonic hindlimb morphogenesis GO:0035116 32 0.027
heart morphogenesis GO:0003007 178 0.027
Mouse
cell proliferation in hindbrain GO:0021534 10 0.027
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.027
negative regulation of detection of glucose GO:2000971 1 0.027
spinal cord association neuron differentiation GO:0021527 14 0.027
cytokine biosynthetic process GO:0042089 68 0.027
renal vesicle induction GO:0072034 3 0.027
heart contraction GO:0060047 93 0.027
Mouse
neurotransmitter transport GO:0006836 76 0.027
regulation of mitotic cell cycle GO:0007346 126 0.027
female gamete generation GO:0007292 74 0.027
specification of organ identity GO:0010092 30 0.027
midbrain development GO:0030901 35 0.027
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.027
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.027
lung morphogenesis GO:0060425 50 0.026
mesenchyme development GO:0060485 152 0.026
negative regulation of cytokine production GO:0001818 84 0.026
morphogenesis of a branching structure GO:0001763 203 0.026
detection of stimulus GO:0051606 84 0.026
prostate gland morphogenesis GO:0060512 32 0.026
gabaergic neuron differentiation GO:0097154 11 0.026
regulation of fat cell differentiation GO:0045598 81 0.026
negative regulation of synapse assembly GO:0051964 3 0.026
regulation of stem cell proliferation GO:0072091 78 0.026
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.026
action potential GO:0001508 78 0.026
adult locomotory behavior GO:0008344 91 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
regulation of systemic arterial blood pressure GO:0003073 61 0.026
Mouse
cerebellar granule cell precursor proliferation GO:0021930 10 0.026
positive regulation of neuroblast proliferation GO:0002052 19 0.026
learning GO:0007612 98 0.026
defense response to other organism GO:0098542 197 0.026
catecholamine metabolic process GO:0006584 30 0.026
regulation of corticosterone secretion GO:2000852 2 0.026
regulation of nuclear division GO:0051783 56 0.026
regulation of b cell proliferation GO:0030888 39 0.026
regulation of cell cycle process GO:0010564 160 0.025
positive regulation of neuron differentiation GO:0045666 141 0.025
response to growth factor GO:0070848 198 0.025
apoptotic signaling pathway GO:0097190 306 0.025
cardiac muscle tissue development GO:0048738 130 0.025
Mouse
apoptotic process involved in morphogenesis GO:0060561 25 0.025
regulation of t cell activation GO:0050863 170 0.025
astrocyte fate commitment GO:0060018 4 0.025
somite development GO:0061053 81 0.025
prostate gland epithelium morphogenesis GO:0060740 31 0.025

Klk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org