Mus musculus

0 known processes

Kmo

kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)

(Aliases: AI046660)

Kmo biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
innate immune response GO:0045087 157 0.323
activation of immune response GO:0002253 138 0.226
regulation of innate immune response GO:0045088 91 0.202
cytokine production GO:0001816 319 0.163
regulation of defense response GO:0031347 233 0.148
immune effector process GO:0002252 321 0.139
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.131
regulation of cytokine production GO:0001817 266 0.128
positive regulation of innate immune response GO:0045089 80 0.119
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.116
immune response activating signal transduction GO:0002757 116 0.115
oxidation reduction process GO:0055114 342 0.105
immune response regulating signaling pathway GO:0002764 125 0.102
myeloid cell differentiation GO:0030099 233 0.101
negative regulation of immune system process GO:0002683 209 0.097
detection of yeast GO:0001879 2 0.090
cellular response to lipid GO:0071396 145 0.088
response to molecule of fungal origin GO:0002238 4 0.085
cellular amino acid metabolic process GO:0006520 103 0.082
detection of fungus GO:0016046 2 0.081
membrane organization GO:0061024 245 0.078
response to molecule of bacterial origin GO:0002237 143 0.075
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.075
regulation of cell activation GO:0050865 289 0.074
positive regulation of defense response GO:0031349 124 0.073
negative regulation of immune effector process GO:0002698 55 0.070
regulation of secretion GO:0051046 274 0.068
cellular response to lipopolysaccharide GO:0071222 77 0.067
regulation of lymphocyte activation GO:0051249 240 0.067
positive regulation of cytokine production GO:0001819 174 0.066
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.065
activation of innate immune response GO:0002218 56 0.065
leukocyte mediated immunity GO:0002443 174 0.065
cellular ketone metabolic process GO:0042180 84 0.064
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.062
regulation of cellular ketone metabolic process GO:0010565 66 0.061
regulation of secretion by cell GO:1903530 249 0.061
reactive nitrogen species metabolic process GO:2001057 0 0.060
cation transport GO:0006812 399 0.059
negative regulation of defense response GO:0031348 77 0.058
regulation of lymphocyte proliferation GO:0050670 117 0.057
maintenance of location GO:0051235 89 0.057
regulation of establishment of protein localization GO:0070201 181 0.057
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.056
helper t cell chemotaxis GO:0035704 1 0.056
defense response to bacterium GO:0042742 119 0.056
cellular response to biotic stimulus GO:0071216 92 0.055
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.053
cellular response to molecule of bacterial origin GO:0071219 83 0.051
protein secretion GO:0009306 111 0.051
regulation of leukocyte mediated immunity GO:0002703 104 0.050
pattern recognition receptor signaling pathway GO:0002221 47 0.049
adaptive immune response GO:0002250 155 0.049
divalent inorganic cation transport GO:0072511 178 0.049
cellular lipid metabolic process GO:0044255 323 0.049
g protein coupled receptor signaling pathway GO:0007186 243 0.049
leukocyte proliferation GO:0070661 172 0.048
cell killing GO:0001906 67 0.046
amine metabolic process GO:0009308 45 0.045
cellular chemical homeostasis GO:0055082 215 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
regulation of protein localization GO:0032880 231 0.043
t cell activation GO:0042110 289 0.043
regulation of ion homeostasis GO:2000021 64 0.043
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.043
cellular response to molecule of fungal origin GO:0071226 2 0.043
regulation of t cell activation GO:0050863 170 0.042
positive regulation of secretion GO:0051047 130 0.042
response to organonitrogen compound GO:0010243 246 0.042
humoral immune response GO:0006959 57 0.041
regulation of apoptotic signaling pathway GO:2001233 197 0.041
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.040
regulation of ion transport GO:0043269 215 0.040
leukocyte differentiation GO:0002521 342 0.039
cytokine secretion GO:0050663 72 0.039
positive regulation of immune effector process GO:0002699 107 0.039
ras protein signal transduction GO:0007265 77 0.039
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.039
regulation of cell killing GO:0031341 40 0.038
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.038
defense response to other organism GO:0098542 197 0.038
cellular amine metabolic process GO:0044106 44 0.038
regulation of reactive oxygen species metabolic process GO:2000377 40 0.037
regulation of natural killer cell mediated immunity GO:0002715 19 0.037
cellular homeostasis GO:0019725 240 0.037
lymphocyte mediated immunity GO:0002449 139 0.037
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.036
response to organic cyclic compound GO:0014070 198 0.036
response to lipopolysaccharide GO:0032496 128 0.036
aromatic compound catabolic process GO:0019439 286 0.035
nitrogen compound transport GO:0071705 271 0.035
regulation of protein transport GO:0051223 163 0.035
natural killer cell mediated immunity GO:0002228 29 0.035
divalent metal ion transport GO:0070838 172 0.034
mapk cascade GO:0000165 281 0.034
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.034
positive regulation of protein transport GO:0051222 93 0.034
calcium ion transport GO:0006816 159 0.033
organic cyclic compound catabolic process GO:1901361 295 0.033
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.033
innate immune response activating signal transduction GO:0002758 50 0.033
reactive oxygen species metabolic process GO:0072593 84 0.032
cell type specific apoptotic process GO:0097285 268 0.032
nucleoside catabolic process GO:0009164 206 0.032
reactive oxygen species biosynthetic process GO:1903409 8 0.032
negative regulation of molecular function GO:0044092 258 0.032
sequestering of calcium ion GO:0051208 18 0.032
regulation of body fluid levels GO:0050878 162 0.032
response to acid chemical GO:0001101 111 0.032
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
inflammatory response GO:0006954 244 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
regulation of protein secretion GO:0050708 82 0.031
positive regulation of interferon alpha production GO:0032727 4 0.031
positive regulation of transferase activity GO:0051347 167 0.031
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.031
purine containing compound metabolic process GO:0072521 311 0.031
b cell activation GO:0042113 161 0.030
regulation of intracellular transport GO:0032386 159 0.030
regulation of hydrolase activity GO:0051336 246 0.030
sequestering of metal ion GO:0051238 19 0.030
negative regulation of leukocyte mediated immunity GO:0002704 29 0.030
sensory perception GO:0007600 245 0.030
antigen receptor mediated signaling pathway GO:0050851 64 0.030
lipid biosynthetic process GO:0008610 179 0.029
uronic acid metabolic process GO:0006063 2 0.029
cellular response to peptidoglycan GO:0071224 4 0.029
negative regulation of innate immune response GO:0045824 17 0.029
negative regulation of homeostatic process GO:0032845 71 0.029
cytokine metabolic process GO:0042107 71 0.029
steroid metabolic process GO:0008202 119 0.028
purine nucleoside metabolic process GO:0042278 241 0.028
purine nucleoside triphosphate metabolic process GO:0009144 226 0.028
regulation of immunological synapse formation GO:2000520 2 0.028
transmembrane transport GO:0055085 412 0.028
small molecule biosynthetic process GO:0044283 132 0.028
organic hydroxy compound metabolic process GO:1901615 203 0.028
interferon gamma production GO:0032609 67 0.028
alcohol metabolic process GO:0006066 116 0.028
endocytosis GO:0006897 168 0.028
regulation of leukocyte proliferation GO:0070663 121 0.028
branching morphogenesis of an epithelial tube GO:0048754 159 0.028
negative regulation of cell activation GO:0050866 111 0.027
protein maturation GO:0051604 176 0.027
positive regulation of secretion by cell GO:1903532 114 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
regulation of lymphocyte mediated immunity GO:0002706 84 0.027
rho protein signal transduction GO:0007266 32 0.026
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.026
leukocyte activation involved in immune response GO:0002366 126 0.026
regulation of homeostatic process GO:0032844 182 0.026
apoptotic signaling pathway GO:0097190 306 0.026
carbohydrate homeostasis GO:0033500 128 0.026
monocyte extravasation GO:0035696 2 0.026
tumor necrosis factor production GO:0032640 50 0.025
regulation of organelle organization GO:0033043 289 0.025
carbohydrate derivative catabolic process GO:1901136 231 0.025
regulation of vesicle mediated transport GO:0060627 139 0.025
regulation of cell motility GO:2000145 236 0.025
glucose homeostasis GO:0042593 128 0.025
regulation of mapk cascade GO:0043408 248 0.025
cellular response to organonitrogen compound GO:0071417 145 0.025
phagocytosis GO:0006909 66 0.025
carbohydrate metabolic process GO:0005975 230 0.025
cell activation involved in immune response GO:0002263 126 0.025
hemostasis GO:0007599 78 0.025
peptidyl amino acid modification GO:0018193 336 0.025
cell recognition GO:0008037 83 0.025
regulation of cellular catabolic process GO:0031329 242 0.025
regulation of response to wounding GO:1903034 189 0.025
regulation of cytokine secretion GO:0050707 61 0.025
regulation of t cell proliferation GO:0042129 92 0.024
nucleotide metabolic process GO:0009117 332 0.024
regulation of inflammatory response GO:0050727 147 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
cytoplasmic transport GO:0016482 234 0.024
regulation of t cell costimulation GO:2000523 2 0.024
negative regulation of leukocyte differentiation GO:1902106 51 0.024
positive regulation of mapk cascade GO:0043410 170 0.024
lymphocyte proliferation GO:0046651 164 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
monocarboxylic acid metabolic process GO:0032787 191 0.024
natural killer cell mediated cytotoxicity GO:0042267 29 0.024
fatty acid metabolic process GO:0006631 121 0.024
positive regulation of lymphocyte activation GO:0051251 140 0.023
cellular divalent inorganic cation homeostasis GO:0072503 127 0.023
single organismal cell cell adhesion GO:0016337 131 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
intestinal epithelial structure maintenance GO:0060729 4 0.023
positive regulation of kinase activity GO:0033674 155 0.023
divalent inorganic cation homeostasis GO:0072507 138 0.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
positive regulation of protein modification process GO:0031401 299 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.023
antigen processing and presentation GO:0019882 47 0.022
positive regulation of cytokine secretion GO:0050715 41 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
response to testosterone GO:0033574 3 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
glycoprotein biosynthetic process GO:0009101 89 0.022
coagulation GO:0050817 78 0.022
heterocycle catabolic process GO:0046700 280 0.022
cellular response to cytokine stimulus GO:0071345 189 0.022
cytokine biosynthetic process GO:0042089 68 0.022
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.022
regulation of membrane potential GO:0042391 192 0.021
nucleotide catabolic process GO:0009166 217 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.021
regulation of cytokine biosynthetic process GO:0042035 59 0.021
fat soluble vitamin biosynthetic process GO:0042362 4 0.021
positive regulation of map kinase activity GO:0043406 84 0.021
myeloid leukocyte differentiation GO:0002573 119 0.021
anatomical structure homeostasis GO:0060249 145 0.021
regulation of protein kinase activity GO:0045859 232 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
response to host GO:0075136 3 0.021
multicellular organismal signaling GO:0035637 91 0.021
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.021
cellular calcium ion homeostasis GO:0006874 119 0.021
regulation of actin cytoskeleton organization GO:0032956 84 0.020
lymphocyte differentiation GO:0030098 242 0.020
hematopoietic progenitor cell differentiation GO:0002244 143 0.020
glycoprotein metabolic process GO:0009100 116 0.020
morphogenesis of a branching epithelium GO:0061138 193 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
metal ion homeostasis GO:0055065 189 0.020
leukocyte mediated cytotoxicity GO:0001909 62 0.020
positive regulation of leukocyte proliferation GO:0070665 73 0.020
ossification GO:0001503 216 0.020
positive regulation of t cell costimulation GO:2000525 2 0.020
eosinophil activation involved in immune response GO:0002278 1 0.020
regulation of tumor necrosis factor production GO:0032680 49 0.020
positive regulation of tumor necrosis factor production GO:0032760 30 0.020
regulation of cytoplasmic transport GO:1903649 112 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
regulation of protein maturation GO:1903317 96 0.019
regulation of interferon beta biosynthetic process GO:0045357 4 0.019
toll like receptor signaling pathway GO:0002224 38 0.019
muscle tissue development GO:0060537 308 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
dna metabolic process GO:0006259 303 0.019
detection of external biotic stimulus GO:0098581 9 0.019
positive regulation of leukocyte mediated immunity GO:0002705 70 0.019
protein processing GO:0016485 163 0.019
lipid localization GO:0010876 126 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
cell adhesion GO:0007155 329 0.019
t helper 17 cell chemotaxis GO:0035705 1 0.019
purine containing compound catabolic process GO:0072523 213 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
microglial cell activation involved in immune response GO:0002282 1 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
regulation of ras protein signal transduction GO:0046578 114 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
regulation of proteolysis GO:0030162 164 0.018
interleukin 8 production GO:0032637 4 0.018
negative regulation of eosinophil degranulation GO:0043310 1 0.018
positive regulation of cell activation GO:0050867 158 0.018
immune complex clearance GO:0002434 2 0.018
regulation of actin filament based process GO:0032970 99 0.018
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.018
regulation of hormone levels GO:0010817 211 0.018
intracellular protein transport GO:0006886 204 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
nucleoside metabolic process GO:0009116 246 0.018
positive regulation of t cell extravasation GO:2000409 2 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
calcium ion homeostasis GO:0055074 127 0.018
actin filament polymerization GO:0030041 44 0.018
organelle localization GO:0051640 179 0.018
epithelial cell proliferation GO:0050673 174 0.018
macromolecule catabolic process GO:0009057 281 0.018
ribonucleotide catabolic process GO:0009261 208 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
regulation of erk1 and erk2 cascade GO:0070372 71 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
eosinophil activation GO:0043307 1 0.017
myeloid leukocyte activation GO:0002274 83 0.017
t cell proliferation GO:0042098 120 0.017
organophosphate catabolic process GO:0046434 232 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
regulation of interferon gamma production GO:0032649 57 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
interferon beta biosynthetic process GO:0045350 4 0.017
protein localization to nucleus GO:0034504 121 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
cellular alcohol metabolic process GO:0044107 3 0.017
regulated secretory pathway GO:0045055 32 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
leukocyte migration GO:0050900 124 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
positive regulation of cell death GO:0010942 224 0.017
angiogenesis GO:0001525 201 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.017
cellular response to testosterone stimulus GO:0071394 1 0.017
regulation of cell migration GO:0030334 219 0.017
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.016
exocytosis GO:0006887 121 0.016
regulation of kinase activity GO:0043549 249 0.016
positive regulation by symbiont of host defense response GO:0052509 1 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
regulation of cytoskeleton organization GO:0051493 122 0.016
mature dendritic cell differentiation GO:0097029 3 0.016
regulation of eosinophil degranulation GO:0043309 1 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
blood vessel morphogenesis GO:0048514 285 0.016
forebrain development GO:0030900 302 0.016
ion transmembrane transport GO:0034220 361 0.016
olfactory learning GO:0008355 2 0.016
regulation of transferase activity GO:0051338 263 0.016
erk1 and erk2 cascade GO:0070371 77 0.016
regulation of cell cycle GO:0051726 281 0.016
organic acid biosynthetic process GO:0016053 86 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
calcium ion transport into cytosol GO:0060402 48 0.016
carboxylic acid biosynthetic process GO:0046394 86 0.016
regulation of interleukin 8 secretion GO:2000482 2 0.016
cofactor metabolic process GO:0051186 80 0.016
positive regulation of interleukin 18 production GO:0032741 2 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
regulation of interleukin 8 production GO:0032677 3 0.015
response to drug GO:0042493 75 0.015
regulation of endocytosis GO:0030100 69 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.015
actin filament organization GO:0007015 113 0.015
cellular alcohol biosynthetic process GO:0044108 3 0.015
positive regulation of cell killing GO:0031343 33 0.015
eosinophil mediated immunity GO:0002447 1 0.015
negative regulation of macrophage apoptotic process GO:2000110 3 0.015
negative regulation of phospholipase activity GO:0010519 4 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
regulation of coagulation GO:0050818 31 0.015
chemotaxis GO:0006935 247 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
blood coagulation GO:0007596 76 0.015
single organism cell adhesion GO:0098602 156 0.015
interleukin 12 secretion GO:0072610 3 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
transepithelial chloride transport GO:0030321 4 0.015
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
regulation of b cell proliferation GO:0030888 39 0.015
plasma membrane organization GO:0007009 90 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
organic hydroxy compound transport GO:0015850 93 0.015
cognition GO:0050890 149 0.015
axonogenesis GO:0007409 274 0.015
negative regulation of hydrolase activity GO:0051346 71 0.014
transmission of nerve impulse GO:0019226 76 0.014
protein polymerization GO:0051258 57 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
organic anion transport GO:0015711 137 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
regulation of cellular response to stress GO:0080135 159 0.014
cellular ion homeostasis GO:0006873 165 0.014
tissue homeostasis GO:0001894 115 0.014
regulation of phagocytosis GO:0050764 33 0.014
cellular protein complex assembly GO:0043623 116 0.014
positive regulation of phagocytosis GO:0050766 26 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
sulfur compound metabolic process GO:0006790 100 0.014
signal transduction in absence of ligand GO:0038034 55 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
cellular response to external stimulus GO:0071496 88 0.014
microglial cell activation GO:0001774 3 0.014
regulation of calcium ion transport GO:0051924 69 0.014
negative regulation of phagocytosis GO:0050765 4 0.014
t cell differentiation GO:0030217 174 0.014
action potential GO:0001508 78 0.014
nitric oxide biosynthetic process GO:0006809 25 0.014
endomembrane system organization GO:0010256 147 0.014
regulation of natural killer cell activation GO:0032814 22 0.014
positive regulation of endocytosis GO:0045807 42 0.014
detection of stimulus GO:0051606 84 0.014
regulation of adaptive immune response GO:0002819 90 0.014
regulation of monocyte extravasation GO:2000437 2 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
modification by symbiont of host morphology or physiology GO:0044003 4 0.013
protein localization to organelle GO:0033365 185 0.013
positive regulation of cytokine biosynthetic process GO:0042108 40 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
organelle assembly GO:0070925 177 0.013
positive regulation of nervous system development GO:0051962 221 0.013
leukocyte degranulation GO:0043299 27 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
erythrocyte differentiation GO:0030218 88 0.013
response to extracellular stimulus GO:0009991 127 0.013
positive regulation of immunological synapse formation GO:2000522 1 0.013
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.013
protein catabolic process GO:0030163 221 0.013
negative regulation of secretion GO:0051048 61 0.013
neuronal action potential GO:0019228 54 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
stress activated mapk cascade GO:0051403 80 0.013
immune complex clearance by monocytes and macrophages GO:0002436 2 0.013
t cell extravasation GO:0072683 4 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 1 0.013
sterol metabolic process GO:0016125 58 0.013
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.013
natural killer cell activation GO:0030101 44 0.013
activation of mapk activity GO:0000187 59 0.013
response to peptide GO:1901652 136 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
actin cytoskeleton organization GO:0030036 220 0.013
positive regulation of cell motility GO:2000147 116 0.013
cytosolic calcium ion homeostasis GO:0051480 70 0.013
monosaccharide metabolic process GO:0005996 106 0.013
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.013
negative regulation of protein processing GO:0010955 79 0.013
regulation of monocyte chemotaxis GO:0090025 3 0.012
striated muscle tissue development GO:0014706 293 0.012
cation homeostasis GO:0055080 212 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
positive regulation of t cell activation GO:0050870 101 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.012
growth involved in symbiotic interaction GO:0044110 23 0.012
mitotic cell cycle GO:0000278 195 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
membrane lipid metabolic process GO:0006643 53 0.012
cellular response to nutrient levels GO:0031669 64 0.012
mitochondrion organization GO:0007005 134 0.012
homeostasis of number of cells GO:0048872 210 0.012
response to nutrient levels GO:0031667 109 0.012
cellular response to steroid hormone stimulus GO:0071383 33 0.012
regulation of map kinase activity GO:0043405 120 0.012
wound healing GO:0042060 157 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
regulation of protein processing GO:0070613 96 0.012
b cell proliferation GO:0042100 53 0.012
blood circulation GO:0008015 195 0.012
lipid transport GO:0006869 98 0.012
hormone metabolic process GO:0042445 86 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
gland development GO:0048732 330 0.012
nuclear transport GO:0051169 139 0.012
progesterone metabolic process GO:0042448 4 0.012
glucuronate metabolic process GO:0019585 2 0.012
positive regulation of interferon gamma production GO:0032729 39 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
negative regulation of growth GO:0045926 99 0.012
response to peptide hormone GO:0043434 127 0.012
cerebral cortex development GO:0021987 86 0.012
regulation of blood coagulation GO:0030193 28 0.012
response to interferon gamma GO:0034341 34 0.012
organelle fission GO:0048285 170 0.012
glycerolipid metabolic process GO:0046486 122 0.012
detection of molecule of bacterial origin GO:0032490 2 0.012
organ regeneration GO:0031100 2 0.012
telencephalon development GO:0021537 186 0.012
anion transport GO:0006820 177 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.012
peptide transport GO:0015833 133 0.012
dna endoreduplication GO:0042023 4 0.011
leukocyte apoptotic process GO:0071887 71 0.011
positive regulation of protein secretion GO:0050714 52 0.011
release of sequestered calcium ion into cytosol GO:0051209 42 0.011
learning GO:0007612 98 0.011
protein localization to membrane GO:0072657 108 0.011
neural precursor cell proliferation GO:0061351 121 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
tissue remodeling GO:0048771 102 0.011
regulation of system process GO:0044057 200 0.011
eosinophil degranulation GO:0043308 1 0.011
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.011
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.011
regulation of interleukin 1 production GO:0032652 26 0.011
positive regulation of organelle organization GO:0010638 128 0.011
muscle cell differentiation GO:0042692 261 0.011
methylation GO:0032259 134 0.011
organophosphate biosynthetic process GO:0090407 122 0.011

Kmo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.046
disease of anatomical entity DOID:7 0 0.046
hematopoietic system disease DOID:74 0 0.038
disease of metabolism DOID:0014667 0 0.030
nervous system disease DOID:863 0 0.024
musculoskeletal system disease DOID:17 0 0.018
connective tissue disease DOID:65 0 0.018
sensory system disease DOID:0050155 0 0.014
inherited metabolic disorder DOID:655 0 0.013
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
central nervous system disease DOID:331 0 0.012
bone disease DOID:0080001 0 0.011