Mus musculus

33 known processes

Kpnb1

karyopherin (importin) beta 1

(Aliases: AA409963,MGC8315,IPOB,Impnb)

Kpnb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytoplasmic transport GO:0016482 234 0.729
protein desumoylation GO:0016926 2 0.677
Yeast
establishment of protein localization to organelle GO:0072594 118 0.642
translation GO:0006412 93 0.580
protein localization to nucleus GO:0034504 121 0.570
mitotic cell cycle process GO:1903047 159 0.459
Worm Fly
mitotic cell cycle GO:0000278 195 0.449
Worm Fly
cellular macromolecule catabolic process GO:0044265 206 0.441
organelle fission GO:0048285 170 0.378
Fly
nuclear transport GO:0051169 139 0.373
protein import GO:0017038 101 0.373
nucleocytoplasmic transport GO:0006913 139 0.333
posttranscriptional regulation of gene expression GO:0010608 155 0.328
intracellular protein transport GO:0006886 204 0.303
single organism nuclear import GO:1902593 95 0.295
positive regulation of cytoplasmic transport GO:1903651 40 0.273
Fly
spermatogenesis GO:0007283 284 0.259
oocyte anterior posterior axis specification GO:0007314 2 0.256
positive regulation of intracellular transport GO:0032388 70 0.253
Fly
protein localization to organelle GO:0033365 185 0.250
microtubule based process GO:0007017 236 0.241
Worm
methylation GO:0032259 134 0.228
regulation of protein import into nucleus GO:0042306 52 0.222
Fly
mrna transport GO:0051028 13 0.218
regulation of intracellular protein transport GO:0033157 82 0.215
Fly
regulation of cell cycle GO:0051726 281 0.188
protein targeting GO:0006605 143 0.176
gene silencing by rna GO:0031047 19 0.175
aromatic compound catabolic process GO:0019439 286 0.174
ribonucleoprotein complex disassembly GO:0032988 3 0.148
male gamete generation GO:0048232 285 0.146
oocyte construction GO:0007308 2 0.146
regulation of cytoplasmic transport GO:1903649 112 0.137
Fly
regulation of intracellular transport GO:0032386 159 0.135
Fly
nucleobase containing small molecule metabolic process GO:0055086 352 0.134
protein import into nucleus GO:0006606 95 0.133
germ cell development GO:0007281 185 0.131
Fly
organic cyclic compound catabolic process GO:1901361 295 0.130
nitrogen compound transport GO:0071705 271 0.126
regulation of translation GO:0006417 71 0.122
regulation of protein targeting GO:1903533 61 0.109
Fly
regulation of mrna stability GO:0043488 23 0.106
oocyte axis specification GO:0007309 2 0.103
pole plasm assembly GO:0007315 2 0.101
modification dependent macromolecule catabolic process GO:0043632 133 0.098
dna metabolic process GO:0006259 303 0.098
nucleotide catabolic process GO:0009166 217 0.097
mitotic nuclear division GO:0007067 48 0.097
Fly
nuclear import GO:0051170 95 0.094
nuclear transcribed mrna catabolic process GO:0000956 16 0.094
regulation of protein transport GO:0051223 163 0.093
Fly
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.093
negative regulation of cellular protein metabolic process GO:0032269 247 0.092
positive regulation of protein localization to nucleus GO:1900182 30 0.088
Fly
protein methylation GO:0006479 81 0.085
nuclear export GO:0051168 34 0.083
organelle assembly GO:0070925 177 0.078
nuclear division GO:0000280 158 0.078
Fly
meiotic nuclear division GO:0007126 115 0.077
rna localization GO:0006403 23 0.077
nucleus organization GO:0006997 45 0.075
Yeast
purine nucleoside metabolic process GO:0042278 241 0.074
meiotic cell cycle GO:0051321 122 0.073
cellular response to amino acid stimulus GO:0071230 29 0.070
macromolecule methylation GO:0043414 120 0.070
mrna metabolic process GO:0016071 84 0.069
establishment of rna localization GO:0051236 18 0.065
nucleoside catabolic process GO:0009164 206 0.063
regionalization GO:0003002 337 0.063
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.062
ribonucleotide metabolic process GO:0009259 291 0.061
cellular response to cytokine stimulus GO:0071345 189 0.061
regulation of organelle organization GO:0033043 289 0.059
rna processing GO:0006396 105 0.056
regulation of cellular component biogenesis GO:0044087 181 0.055
cellular nitrogen compound catabolic process GO:0044270 280 0.053
dendrite development GO:0016358 115 0.053
ossification GO:0001503 216 0.052
intracellular mrna localization GO:0008298 4 0.052
response to organonitrogen compound GO:0010243 246 0.051
regulation of cell cycle process GO:0010564 160 0.051
nucleobase containing compound transport GO:0015931 27 0.050
rna interference GO:0016246 2 0.049
spermatid differentiation GO:0048515 115 0.049
maternal determination of anterior posterior axis embryo GO:0008358 2 0.048
microtubule cytoskeleton organization GO:0000226 157 0.047
Worm
posttranscriptional gene silencing by rna GO:0035194 10 0.047
regulation of protein localization GO:0032880 231 0.046
Fly
positive regulation of intracellular protein transport GO:0090316 42 0.045
Fly
ribose phosphate metabolic process GO:0019693 291 0.045
response to organic cyclic compound GO:0014070 198 0.045
rna transport GO:0050658 18 0.045
heterocycle catabolic process GO:0046700 280 0.045
purine nucleoside triphosphate metabolic process GO:0009144 226 0.044
cell type specific apoptotic process GO:0097285 268 0.043
nucleic acid transport GO:0050657 18 0.042
ribonucleoside triphosphate catabolic process GO:0009203 199 0.041
mrna export from nucleus GO:0006406 11 0.041
glycosyl compound metabolic process GO:1901657 246 0.040
regulation of nucleocytoplasmic transport GO:0046822 73 0.039
Fly
maintenance of location GO:0051235 89 0.039
protein complex disassembly GO:0043241 40 0.039
regulation of cell division GO:0051302 76 0.038
regulation of protein localization to nucleus GO:1900180 60 0.038
Fly
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.038
Fly
response to light stimulus GO:0009416 135 0.038
cell recognition GO:0008037 83 0.038
protein modification by small protein conjugation or removal GO:0070647 207 0.038
Yeast
regulation of cytoskeleton organization GO:0051493 122 0.038
ribonucleoside metabolic process GO:0009119 245 0.037
nucleoside metabolic process GO:0009116 246 0.037
cellular response to organonitrogen compound GO:0071417 145 0.037
positive regulation of protein import into nucleus GO:0042307 26 0.037
Fly
negative regulation of protein metabolic process GO:0051248 282 0.037
cellular amino acid metabolic process GO:0006520 103 0.035
regulation of mitotic cell cycle GO:0007346 126 0.035
response to amino acid GO:0043200 37 0.035
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 12 0.034
rna dependent dna replication GO:0006278 3 0.034
adult behavior GO:0030534 135 0.033
purine nucleoside triphosphate catabolic process GO:0009146 203 0.033
negative regulation of molecular function GO:0044092 258 0.033
dna modification GO:0006304 50 0.032
protein export from nucleus GO:0006611 20 0.032
stem cell development GO:0048864 219 0.032
nucleotide metabolic process GO:0009117 332 0.032
stem cell differentiation GO:0048863 268 0.032
regulation of gtp catabolic process GO:0033124 113 0.031
Yeast
receptor mediated endocytosis GO:0006898 51 0.030
mesenchymal cell development GO:0014031 93 0.029
epithelial to mesenchymal transition GO:0001837 47 0.029
actin cytoskeleton organization GO:0030036 220 0.029
Fly
protein modification by small protein conjugation GO:0032446 187 0.028
gtp catabolic process GO:0006184 143 0.028
multicellular organismal signaling GO:0035637 91 0.028
response to inorganic substance GO:0010035 96 0.027
regulation of nucleotide metabolic process GO:0006140 169 0.027
Yeast
mitotic sister chromatid segregation GO:0000070 14 0.027
macromolecule catabolic process GO:0009057 281 0.027
cell cell recognition GO:0009988 44 0.027
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.026
spindle organization GO:0007051 28 0.026
Worm
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.026
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.026
response to extracellular stimulus GO:0009991 127 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
cell maturation GO:0048469 127 0.025
female gamete generation GO:0007292 74 0.025
Fly
cellular protein complex assembly GO:0043623 116 0.025
Yeast Fly
protein alkylation GO:0008213 81 0.025
chromatin organization GO:0006325 206 0.025
regulation of multi organism process GO:0043900 111 0.024
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.024
nuclear mrna surveillance GO:0071028 1 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
toxin transport GO:1901998 38 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
alpha amino acid metabolic process GO:1901605 59 0.023
development of primary sexual characteristics GO:0045137 143 0.023
mrna catabolic process GO:0006402 22 0.023
metaphase plate congression GO:0051310 2 0.023
regulation of rna splicing GO:0043484 37 0.023
regulation of rna stability GO:0043487 26 0.023
mesenchyme development GO:0060485 152 0.023
ribonucleotide catabolic process GO:0009261 208 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.022
response to radiation GO:0009314 165 0.022
organophosphate catabolic process GO:0046434 232 0.022
regulation of protein catabolic process GO:0042176 108 0.022
cellular response to acid chemical GO:0071229 68 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
chromosome segregation GO:0007059 48 0.022
body morphogenesis GO:0010171 45 0.022
regulation of proteolysis GO:0030162 164 0.022
adult locomotory behavior GO:0008344 91 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
oogenesis GO:0048477 56 0.021
Fly
guanosine containing compound catabolic process GO:1901069 144 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
regulation of cell projection organization GO:0031344 206 0.020
sperm egg recognition GO:0035036 37 0.020
placenta development GO:0001890 140 0.020
response to alkaloid GO:0043279 34 0.020
response to oxidative stress GO:0006979 123 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
Fly
oocyte differentiation GO:0009994 35 0.020
cellular protein catabolic process GO:0044257 155 0.020
response to acid chemical GO:0001101 111 0.020
b cell activation GO:0042113 161 0.020
muscle system process GO:0003012 141 0.020
ubiquitin dependent protein catabolic process GO:0006511 129 0.019
cell growth GO:0016049 130 0.019
mesenchymal cell differentiation GO:0048762 107 0.019
cardiac muscle contraction GO:0060048 32 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
regulation of cell motility GO:2000145 236 0.019
positive regulation of immune effector process GO:0002699 107 0.019
regulation of mitotic cell cycle phase transition GO:1901990 73 0.019
response to nutrient levels GO:0031667 109 0.018
muscle contraction GO:0006936 101 0.018
purine containing compound metabolic process GO:0072521 311 0.018
purine containing compound catabolic process GO:0072523 213 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
cell division GO:0051301 120 0.018
skin development GO:0043588 220 0.018
protein dna complex subunit organization GO:0071824 28 0.018
organelle localization GO:0051640 179 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.018
Yeast
nucleoside triphosphate metabolic process GO:0009141 230 0.018
digestive system development GO:0055123 200 0.018
regulation of nuclear division GO:0051783 56 0.018
rna export from nucleus GO:0006405 15 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
regulation of protein complex assembly GO:0043254 83 0.017
developmental maturation GO:0021700 193 0.017
posttranscriptional gene silencing GO:0016441 10 0.017
photoreceptor cell development GO:0042461 40 0.017
response to insulin GO:0032868 100 0.017
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.016
positive regulation of cell cycle GO:0045787 92 0.016
wnt signaling pathway GO:0016055 188 0.016
oxidation reduction process GO:0055114 342 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
regulation of cell cycle phase transition GO:1901987 77 0.016
urogenital system development GO:0001655 261 0.016
regulation of neuron projection development GO:0010975 169 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
Yeast
negative regulation of cell proliferation GO:0008285 296 0.016
connective tissue development GO:0061448 179 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
action potential GO:0001508 78 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
Yeast
purine nucleotide metabolic process GO:0006163 302 0.015
nls bearing protein import into nucleus GO:0006607 2 0.015
Fly
maternal process involved in female pregnancy GO:0060135 32 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.015
rna 3 end processing GO:0031123 20 0.015
spermatid development GO:0007286 108 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
neuron apoptotic process GO:0051402 142 0.015
photoreceptor cell morphogenesis GO:0008594 3 0.014
gonad development GO:0008406 141 0.014
multi multicellular organism process GO:0044706 109 0.014
positive regulation of binding GO:0051099 49 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
regulation of protein stability GO:0031647 52 0.014
positive regulation of dendrite development GO:1900006 21 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
Yeast
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 1 0.014
lipid localization GO:0010876 126 0.013
axonogenesis GO:0007409 274 0.013
protein catabolic process GO:0030163 221 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
negative regulation of dna templated transcription termination GO:0060567 1 0.013
lateral inhibition GO:0046331 1 0.013
striated muscle contraction GO:0006941 45 0.013
regulation of protein binding GO:0043393 60 0.013
viral gene expression GO:0019080 3 0.013
attachment of spindle microtubules to kinetochore GO:0008608 4 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
positive regulation of nfat protein import into nucleus GO:0051533 1 0.013
Fly
regulation of cell growth GO:0001558 91 0.012
somatic diversification of immunoglobulins GO:0016445 43 0.012
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.012
sister chromatid segregation GO:0000819 20 0.012
transmission of nerve impulse GO:0019226 76 0.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.012
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.012
interspecies interaction between organisms GO:0044419 83 0.012
histone lysine methylation GO:0034968 50 0.012
regulation of hydrolase activity GO:0051336 246 0.012
Yeast
sensory organ morphogenesis GO:0090596 242 0.012
positive regulation of leukocyte mediated immunity GO:0002705 70 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
muscle cell differentiation GO:0042692 261 0.012
locomotory behavior GO:0007626 195 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
Yeast
regulation of protein export from nucleus GO:0046825 11 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
intracellular receptor signaling pathway GO:0030522 74 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
epidermis development GO:0008544 187 0.011
maternal placenta development GO:0001893 20 0.011
hindbrain development GO:0030902 128 0.011
establishment of organelle localization GO:0051656 122 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
negative regulation of viral genome replication GO:0045071 10 0.011
negative regulation of multi organism process GO:0043901 68 0.011
positive regulation of protein modification process GO:0031401 299 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
regulation of cell migration GO:0030334 219 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
positive regulation of organelle organization GO:0010638 128 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
compound eye development GO:0048749 1 0.011
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.011
blood vessel morphogenesis GO:0048514 285 0.011
cofactor metabolic process GO:0051186 80 0.011
anatomical structure homeostasis GO:0060249 145 0.011
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.011
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.011
regulation of transcription factor import into nucleus GO:0042990 24 0.011
Fly
multicellular organism growth GO:0035264 161 0.011
endocytosis GO:0006897 168 0.011
negative regulation of cell development GO:0010721 169 0.011
prostate glandular acinus development GO:0060525 12 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
positive regulation of rna splicing GO:0033120 12 0.010
cellular response to oxidative stress GO:0034599 76 0.010
skeletal system development GO:0001501 356 0.010
positive regulation of cell activation GO:0050867 158 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.010
protein ubiquitination GO:0016567 171 0.010
positive regulation of translation GO:0045727 19 0.010
guanosine containing compound metabolic process GO:1901068 144 0.010
rna catabolic process GO:0006401 29 0.010
regulation of cytokine production GO:0001817 266 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
dna templated transcription termination GO:0006353 4 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
Yeast
tissue homeostasis GO:0001894 115 0.010
cellular ketone metabolic process GO:0042180 84 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
Yeast
embryonic skeletal system development GO:0048706 120 0.010

Kpnb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038
central nervous system disease DOID:331 0 0.030
large intestine cancer DOID:5672 0 0.021
colon cancer DOID:219 0 0.021
gastrointestinal system cancer DOID:3119 0 0.021
intestinal cancer DOID:10155 0 0.021
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.021
colorectal cancer DOID:9256 0 0.021
neurodegenerative disease DOID:1289 0 0.014