Mus musculus

35 known processes

Krt6b

keratin 6B

(Aliases: MGC141272,BB144589,mK6[b],Krt2-6b)

Krt6b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.341
intermediate filament based process GO:0045103 27 0.314
cellular response to cytokine stimulus GO:0071345 189 0.287
Mouse
regulation of cytokine production GO:0001817 266 0.264
cytokine mediated signaling pathway GO:0019221 115 0.212
Mouse
ion transmembrane transport GO:0034220 361 0.172
cytokine production GO:0001816 319 0.169
intermediate filament organization GO:0045109 15 0.166
intermediate filament cytoskeleton organization GO:0045104 26 0.158
positive regulation of steroid hormone secretion GO:2000833 2 0.157
transmembrane transport GO:0055085 412 0.146
multicellular organismal homeostasis GO:0048871 164 0.143
hormone secretion GO:0046879 128 0.134
regulation of hormone levels GO:0010817 211 0.134
regulation of secretion GO:0051046 274 0.123
cellular response to cadmium ion GO:0071276 3 0.123
positive regulation of cytokine production GO:0001819 174 0.106
regulation of estrogen secretion GO:2000861 1 0.106
regulation of secretion by cell GO:1903530 249 0.106
keratinocyte differentiation GO:0030216 48 0.100
regulation of defense response GO:0031347 233 0.099
Mouse
g protein coupled receptor internalization GO:0002031 3 0.098
cellular lipid metabolic process GO:0044255 323 0.097
response to organic cyclic compound GO:0014070 198 0.096
hepatocyte apoptotic process GO:0097284 11 0.096
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.094
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.085
circulatory system process GO:0003013 197 0.079
myotube cell development GO:0014904 60 0.078
fatty acid derivative metabolic process GO:1901568 33 0.074
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.072
cellular alcohol biosynthetic process GO:0044108 3 0.072
naphthalene containing compound metabolic process GO:0090420 1 0.069
inorganic ion transmembrane transport GO:0098660 234 0.067
response to stilbenoid GO:0035634 22 0.066
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.065
regulation of establishment of protein localization GO:0070201 181 0.064
renal tubular secretion GO:0097254 2 0.063
cellular amine metabolic process GO:0044106 44 0.063
hematopoietic progenitor cell differentiation GO:0002244 143 0.063
Mouse
positive regulation of cytokine secretion GO:0050715 41 0.061
negative regulation of molecular function GO:0044092 258 0.060
regulation of cytokine secretion GO:0050707 61 0.060
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.060
unsaturated fatty acid metabolic process GO:0033559 31 0.059
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.059
apoptotic signaling pathway GO:0097190 306 0.058
Mouse
immune complex clearance by monocytes and macrophages GO:0002436 2 0.058
negative regulation of cell proliferation GO:0008285 296 0.056
Mouse
defense response to bacterium GO:0042742 119 0.055
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.055
nitrogen compound transport GO:0071705 271 0.055
cellular ketone metabolic process GO:0042180 84 0.055
calcitriol biosynthetic process from calciol GO:0036378 3 0.054
spermatogenesis GO:0007283 284 0.054
inflammatory response GO:0006954 244 0.054
Mouse
defense response to other organism GO:0098542 197 0.052
g protein coupled receptor signaling pathway GO:0007186 243 0.052
vascular process in circulatory system GO:0003018 62 0.052
developmental maturation GO:0021700 193 0.051
innate immune response GO:0045087 157 0.051
regulation of circadian sleep wake cycle GO:0042749 3 0.050
positive regulation of secretion GO:0051047 130 0.049
anatomical structure homeostasis GO:0060249 145 0.045
nucleobase containing small molecule metabolic process GO:0055086 352 0.045
renal system process GO:0003014 48 0.045
regulation of cell cycle GO:0051726 281 0.044
compound eye development GO:0048749 1 0.043
negative regulation of intracellular signal transduction GO:1902532 167 0.043
striated muscle cell development GO:0055002 125 0.043
skin development GO:0043588 220 0.043
extrinsic apoptotic signaling pathway GO:0097191 126 0.043
Mouse
secondary alcohol metabolic process GO:1902652 3 0.042
interspecies interaction between organisms GO:0044419 83 0.042
fat soluble vitamin biosynthetic process GO:0042362 4 0.041
rhythmic process GO:0048511 174 0.041
regulation of kinase activity GO:0043549 249 0.041
energy derivation by oxidation of organic compounds GO:0015980 77 0.041
carbohydrate biosynthetic process GO:0016051 74 0.041
lipid biosynthetic process GO:0008610 179 0.040
cellular response to inorganic substance GO:0071241 37 0.038
peptidyl amino acid modification GO:0018193 336 0.038
regulation of anatomical structure size GO:0090066 178 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.038
positive regulation of secretion by cell GO:1903532 114 0.037
response to testosterone GO:0033574 3 0.037
response to organonitrogen compound GO:0010243 246 0.036
carbohydrate metabolic process GO:0005975 230 0.036
production of molecular mediator of immune response GO:0002440 103 0.036
regulation of map kinase activity GO:0043405 120 0.035
inorganic cation transmembrane transport GO:0098662 207 0.035
negative regulation of defense response GO:0031348 77 0.035
Mouse
positive regulation of hormone secretion GO:0046887 38 0.035
positive regulation of protein secretion GO:0050714 52 0.035
regulation of protein secretion GO:0050708 82 0.035
positive regulation of immunological synapse formation GO:2000522 1 0.034
ribose phosphate metabolic process GO:0019693 291 0.034
nucleotide metabolic process GO:0009117 332 0.034
regulation of system process GO:0044057 200 0.033
regulation of tube size GO:0035150 57 0.033
cellular alcohol metabolic process GO:0044107 3 0.033
organophosphate biosynthetic process GO:0090407 122 0.033
regulation of t cell activation GO:0050863 170 0.033
keratinization GO:0031424 9 0.032
regulation of nucleotide metabolic process GO:0006140 169 0.032
positive regulation of blood pressure GO:0045777 21 0.032
leukocyte differentiation GO:0002521 342 0.032
positive regulation of mapk cascade GO:0043410 170 0.032
cation transport GO:0006812 399 0.031
regulation of lymphocyte activation GO:0051249 240 0.031
monocarboxylic acid metabolic process GO:0032787 191 0.031
male gamete generation GO:0048232 285 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
epidermis development GO:0008544 187 0.031
glycosyl compound catabolic process GO:1901658 206 0.030
epithelial cell proliferation GO:0050673 174 0.030
Mouse
tumor necrosis factor production GO:0032640 50 0.030
synaptic transmission GO:0007268 329 0.029
generation of precursor metabolites and energy GO:0006091 103 0.029
porphyrin containing compound metabolic process GO:0006778 22 0.029
cell maturation GO:0048469 127 0.028
positive regulation of protein transport GO:0051222 93 0.028
tissue homeostasis GO:0001894 115 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
vitamin d3 metabolic process GO:0070640 3 0.028
cellular carbohydrate metabolic process GO:0044262 119 0.028
glycoprotein biosynthetic process GO:0009101 89 0.028
sensory perception GO:0007600 245 0.028
regulation of epidermal cell differentiation GO:0045604 21 0.027
Mouse
potassium ion transmembrane transport GO:0071805 43 0.027
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.027
cellular response to organonitrogen compound GO:0071417 145 0.027
lipid transport GO:0006869 98 0.027
regulation of renal sodium excretion GO:0035813 3 0.027
cellular potassium ion transport GO:0071804 43 0.026
cell type specific apoptotic process GO:0097285 268 0.026
Mouse
estrogen secretion GO:0035937 1 0.026
muscle tissue development GO:0060537 308 0.026
ribonucleotide metabolic process GO:0009259 291 0.026
response to radiation GO:0009314 165 0.025
endocytosis GO:0006897 168 0.025
cation transmembrane transport GO:0098655 266 0.025
regulation of blood pressure GO:0008217 93 0.025
cellular response to lipid GO:0071396 145 0.025
regulation of epithelial cell proliferation GO:0050678 141 0.025
Mouse
glycogen metabolic process GO:0005977 32 0.025
cellular amino acid metabolic process GO:0006520 103 0.025
leukocyte proliferation GO:0070661 172 0.025
intracellular receptor signaling pathway GO:0030522 74 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
positive regulation of nucleotide metabolic process GO:0045981 114 0.024
fatty acid metabolic process GO:0006631 121 0.024
regulation of transferase activity GO:0051338 263 0.024
glucose metabolic process GO:0006006 92 0.024
protein secretion GO:0009306 111 0.024
protein maturation GO:0051604 176 0.024
mitochondrion organization GO:0007005 134 0.024
olfactory learning GO:0008355 2 0.023
hexose metabolic process GO:0019318 98 0.023
epidermis morphogenesis GO:0048730 33 0.023
Mouse
regulation of protein transport GO:0051223 163 0.023
interleukin 6 production GO:0032635 58 0.023
cellular ion homeostasis GO:0006873 165 0.022
regulation of leukocyte differentiation GO:1902105 159 0.022
regulation of thyroid hormone generation GO:2000609 4 0.022
linoleic acid metabolic process GO:0043651 6 0.022
purine nucleotide biosynthetic process GO:0006164 65 0.022
amine metabolic process GO:0009308 45 0.022
response to alcohol GO:0097305 48 0.022
regulation of protein localization GO:0032880 231 0.022
muscle cell development GO:0055001 133 0.022
response to lipopolysaccharide GO:0032496 128 0.021
response to tumor necrosis factor GO:0034612 26 0.021
Mouse
muscle fiber development GO:0048747 76 0.021
regulation of tumor necrosis factor production GO:0032680 49 0.021
wound healing GO:0042060 157 0.021
Zebrafish
potassium ion homeostasis GO:0055075 4 0.021
positive regulation of defense response GO:0031349 124 0.021
potassium ion transport GO:0006813 52 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
activation of adenylate cyclase activity GO:0007190 4 0.020
immune effector process GO:0002252 321 0.020
cellular response to organic cyclic compound GO:0071407 87 0.020
positive regulation of hydrolase activity GO:0051345 148 0.020
myotube differentiation GO:0014902 105 0.020
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.020
blood circulation GO:0008015 195 0.020
regulation of keratinocyte differentiation GO:0045616 11 0.020
Mouse
regulation of peptidase activity GO:0052547 96 0.019
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
regulation of protein serine threonine kinase activity GO:0071900 157 0.019
antibacterial peptide biosynthetic process GO:0002780 2 0.019
t cell mediated immunity GO:0002456 50 0.019
histamine induced gastric acid secretion GO:0001697 1 0.019
negative regulation of mapk cascade GO:0043409 65 0.019
circadian rhythm GO:0007623 114 0.019
regulation of cellular amino acid metabolic process GO:0006521 5 0.019
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
calcium ion homeostasis GO:0055074 127 0.018
circadian sleep wake cycle rem sleep GO:0042747 1 0.018
positive regulation of t cell costimulation GO:2000525 2 0.018
striated muscle tissue development GO:0014706 293 0.018
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.018
vitamin metabolic process GO:0006766 23 0.018
protein autoprocessing GO:0016540 2 0.018
sequestering of metal ion GO:0051238 19 0.018
cellular chemical homeostasis GO:0055082 215 0.018
urogenital system development GO:0001655 261 0.018
regulation of smooth muscle contraction GO:0006940 22 0.018
camera type eye development GO:0043010 266 0.018
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure GO:0003072 5 0.018
positive regulation of immune effector process GO:0002699 107 0.018
icosanoid metabolic process GO:0006690 33 0.018
leukocyte mediated immunity GO:0002443 174 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
negative regulation of lymphocyte activation GO:0051250 91 0.017
positive regulation of cell development GO:0010720 237 0.017
defense response to gram positive bacterium GO:0050830 50 0.017
regulation of skeletal muscle fiber development GO:0048742 36 0.017
gastrin induced gastric acid secretion GO:0001698 1 0.017
granulocyte chemotaxis GO:0071621 39 0.017
amide transport GO:0042886 138 0.017
macromolecule catabolic process GO:0009057 281 0.017
membrane hyperpolarization GO:0060081 21 0.017
regulation of immunological synapse formation GO:2000520 2 0.017
regulation of interleukin 1 production GO:0032652 26 0.017
skin morphogenesis GO:0043589 38 0.017
Mouse
response to steroid hormone GO:0048545 56 0.017
glucan metabolic process GO:0044042 32 0.017
calcium ion transport into cytosol GO:0060402 48 0.016
response to peptide hormone GO:0043434 127 0.016
cyclic nucleotide biosynthetic process GO:0009190 44 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
positive regulation of innate immune response GO:0045089 80 0.016
muscle cell differentiation GO:0042692 261 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.016
negative regulation of cell activation GO:0050866 111 0.016
monocyte extravasation GO:0035696 2 0.016
regulation of cellular response to stress GO:0080135 159 0.016
associative learning GO:0008306 61 0.016
divalent inorganic cation transport GO:0072511 178 0.016
angiogenesis GO:0001525 201 0.016
helper t cell chemotaxis GO:0035704 1 0.016
hematopoietic stem cell migration GO:0035701 1 0.016
cytokine secretion GO:0050663 72 0.016
cellularization GO:0007349 1 0.016
regulation of monocyte extravasation GO:2000437 2 0.016
immune complex clearance GO:0002434 2 0.016
response to inorganic substance GO:0010035 96 0.016
tetrapyrrole metabolic process GO:0033013 22 0.016
interleukin 1 production GO:0032612 31 0.016
response to molecule of bacterial origin GO:0002237 143 0.016
negative regulation of inflammatory response GO:0050728 61 0.016
Mouse
response to acid chemical GO:0001101 111 0.016
myeloid leukocyte migration GO:0097529 57 0.016
hair follicle development GO:0001942 85 0.016
Mouse
cellular response to dna damage stimulus GO:0006974 207 0.015
cellular polysaccharide metabolic process GO:0044264 38 0.015
peptide secretion GO:0002790 114 0.015
wnt signaling pathway GO:0016055 188 0.015
Mouse
cell division GO:0051301 120 0.015
purine containing compound metabolic process GO:0072521 311 0.015
regulation of cell cycle process GO:0010564 160 0.015
positive regulation of glucose metabolic process GO:0010907 21 0.015
mature dendritic cell differentiation GO:0097029 3 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
germ cell development GO:0007281 185 0.015
learning GO:0007612 98 0.015
t helper 17 cell chemotaxis GO:0035705 1 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
hair cycle GO:0042633 90 0.014
Mouse
eosinophil degranulation GO:0043308 1 0.014
regulation of mapk cascade GO:0043408 248 0.014
nucleotide biosynthetic process GO:0009165 78 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
organophosphate catabolic process GO:0046434 232 0.014
regulation of eosinophil degranulation GO:0043309 1 0.014
regulation of metal ion transport GO:0010959 106 0.014
t cell activation GO:0042110 289 0.014
regulation of cell activation GO:0050865 289 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
skeletal muscle organ development GO:0060538 163 0.014
microglial cell activation GO:0001774 3 0.014
monosaccharide metabolic process GO:0005996 106 0.014
epithelial cell development GO:0002064 159 0.014
cyclic nucleotide metabolic process GO:0009187 59 0.014
renal sodium excretion GO:0035812 3 0.014
polysaccharide biosynthetic process GO:0000271 20 0.014
regulation of cellular amine metabolic process GO:0033238 20 0.014
fat cell differentiation GO:0045444 160 0.014
regulation of calcium ion transport GO:0051924 69 0.014
lymphocyte differentiation GO:0030098 242 0.013
regulation of interleukin 1 alpha production GO:0032650 4 0.013
temperature homeostasis GO:0001659 26 0.013
cytoplasmic transport GO:0016482 234 0.013
heart process GO:0003015 94 0.013
mapk cascade GO:0000165 281 0.013
cellular response to metal ion GO:0071248 31 0.013
response to xenobiotic stimulus GO:0009410 13 0.013
negative regulation of multi organism process GO:0043901 68 0.013
regulation of carbohydrate biosynthetic process GO:0043255 40 0.013
insulin receptor signaling pathway GO:0008286 49 0.013
sensitization GO:0046960 2 0.013
bone resorption GO:0045453 38 0.013
cellular response to acid chemical GO:0071229 68 0.013
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.013
naphthalene metabolic process GO:0018931 1 0.013
regulation of protein kinase activity GO:0045859 232 0.013
regulation of hydrolase activity GO:0051336 246 0.013
maintenance of location GO:0051235 89 0.013
eosinophil activation GO:0043307 1 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.012
adult behavior GO:0030534 135 0.012
peptidyl serine modification GO:0018209 83 0.012
establishment of skin barrier GO:0061436 14 0.012
Mouse
negative regulation of eosinophil degranulation GO:0043310 1 0.012
regulation of response to wounding GO:1903034 189 0.012
Mouse
protein localization to organelle GO:0033365 185 0.012
positive regulation of t cell extravasation GO:2000409 2 0.012
protein kinase b signaling GO:0043491 74 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
interleukin 1 alpha secretion GO:0050703 3 0.012
response to light stimulus GO:0009416 135 0.012
regulation of fat cell differentiation GO:0045598 81 0.012
positive regulation of camp metabolic process GO:0030816 19 0.012
cellular response to tumor necrosis factor GO:0071356 21 0.012
Mouse
intracellular protein transport GO:0006886 204 0.012
cellular glucan metabolic process GO:0006073 32 0.012
cellular respiration GO:0045333 38 0.012
sequestering of calcium ion GO:0051208 18 0.012
glucose transport GO:0015758 56 0.012
glucan biosynthetic process GO:0009250 14 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
leukocyte chemotaxis GO:0030595 69 0.012
regulation of binding GO:0051098 111 0.011
lymphocyte proliferation GO:0046651 164 0.011
adaptive immune response GO:0002250 155 0.011
acute inflammatory response to antigenic stimulus GO:0002438 12 0.011
positive regulation of epithelial cell proliferation GO:0050679 68 0.011
gland development GO:0048732 330 0.011
positive regulation of neutrophil chemotaxis GO:0090023 12 0.011
positive regulation of peroxisome proliferator activated receptor signaling pathway GO:0035360 2 0.011
regulation of striated muscle cell differentiation GO:0051153 81 0.011
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.011
glucose homeostasis GO:0042593 128 0.011
cytokine metabolic process GO:0042107 71 0.011
divalent metal ion transport GO:0070838 172 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.011
response to alkaline ph GO:0010446 1 0.011
regulation of blood vessel size GO:0050880 56 0.011
long chain fatty acid metabolic process GO:0001676 26 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.011
granulocyte migration GO:0097530 43 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
interleukin 1 beta production GO:0032611 30 0.011
endomembrane system organization GO:0010256 147 0.011
negative regulation of homeostatic process GO:0032845 71 0.011
negative regulation of blood pressure GO:0045776 22 0.011
antimicrobial peptide biosynthetic process GO:0002777 2 0.011
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.011
negative regulation of t cell activation GO:0050868 65 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
cellular response to steroid hormone stimulus GO:0071383 33 0.011
hair follicle morphogenesis GO:0031069 29 0.011
Mouse
skeletal muscle fiber development GO:0048741 58 0.011
regulation of systemic arterial blood pressure GO:0003073 61 0.011
negative regulation of t cell apoptotic process GO:0070233 18 0.010
circadian behavior GO:0048512 13 0.010
cellular response to temperature stimulus GO:0071502 2 0.010
positive regulation of protein modification process GO:0031401 299 0.010
regulation of blood vessel size by renin angiotensin GO:0002034 5 0.010
signal transduction in absence of ligand GO:0038034 55 0.010
regulation of chemokine production GO:0032642 30 0.010
organism emergence from protective structure GO:0071684 4 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
regulation of nucleotide biosynthetic process GO:0030808 34 0.010
glycoprotein metabolic process GO:0009100 116 0.010
spermatid development GO:0007286 108 0.010
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.010
cytokine production involved in immune response GO:0002367 34 0.010
negative regulation of leukocyte differentiation GO:1902106 51 0.010
regulation of transmembrane transport GO:0034762 128 0.010
regulation of feeding behavior GO:0060259 3 0.010
protein heterotetramerization GO:0051290 4 0.010
polysaccharide metabolic process GO:0005976 39 0.010
cellular polysaccharide biosynthetic process GO:0033692 19 0.010

Krt6b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
mouth disease DOID:403 0 0.029
gastrointestinal system disease DOID:77 0 0.029
disease of anatomical entity DOID:7 0 0.029