Mus musculus

7 known processes

Lap3

leucine aminopeptidase 3

(Aliases: AA410100,LAP-3,Pep-7,Pep-S,Peps,Lap,Lapep,Pep7,2410015L10Rik)

Lap3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.403
mitochondrion organization GO:0007005 134 0.136
transmembrane transport GO:0055085 412 0.107
ribose phosphate metabolic process GO:0019693 291 0.105
cellular amino acid catabolic process GO:0009063 25 0.099
purine ribonucleotide metabolic process GO:0009150 290 0.094
cellular nitrogen compound catabolic process GO:0044270 280 0.086
cellular metal ion homeostasis GO:0006875 151 0.086
cellular homeostasis GO:0019725 240 0.081
purine ribonucleoside metabolic process GO:0046128 241 0.078
cellular modified amino acid metabolic process GO:0006575 63 0.076
cation transport GO:0006812 399 0.075
organonitrogen compound catabolic process GO:1901565 264 0.075
organonitrogen compound biosynthetic process GO:1901566 192 0.074
ion transmembrane transport GO:0034220 361 0.074
small molecule catabolic process GO:0044282 71 0.074
carbohydrate derivative catabolic process GO:1901136 231 0.073
ribonucleoside metabolic process GO:0009119 245 0.072
metal ion homeostasis GO:0055065 189 0.069
regulation of apoptotic signaling pathway GO:2001233 197 0.069
oxidation reduction process GO:0055114 342 0.069
carboxylic acid catabolic process GO:0046395 51 0.069
regulation of mitochondrion organization GO:0010821 27 0.066
cation homeostasis GO:0055080 212 0.065
nucleobase containing small molecule metabolic process GO:0055086 352 0.064
organophosphate biosynthetic process GO:0090407 122 0.064
inorganic cation transmembrane transport GO:0098662 207 0.059
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.059
regulation of membrane potential GO:0042391 192 0.056
alpha amino acid metabolic process GO:1901605 59 0.056
nucleoside phosphate metabolic process GO:0006753 338 0.054
endocytosis GO:0006897 168 0.053
ribonucleoside triphosphate metabolic process GO:0009199 220 0.052
aromatic compound catabolic process GO:0019439 286 0.052
organic cyclic compound catabolic process GO:1901361 295 0.051
purine nucleoside metabolic process GO:0042278 241 0.051
response to oxidative stress GO:0006979 123 0.051
ribonucleotide metabolic process GO:0009259 291 0.050
t cell activation GO:0042110 289 0.049
cellular ketone metabolic process GO:0042180 84 0.047
nucleotide biosynthetic process GO:0009165 78 0.047
glycosyl compound metabolic process GO:1901657 246 0.046
purine containing compound metabolic process GO:0072521 311 0.045
cation transmembrane transport GO:0098655 266 0.045
nucleoside metabolic process GO:0009116 246 0.045
regulation of organelle organization GO:0033043 289 0.044
cellular ion homeostasis GO:0006873 165 0.043
protein processing GO:0016485 163 0.042
nucleoside phosphate biosynthetic process GO:1901293 79 0.042
apoptotic signaling pathway GO:0097190 306 0.040
purine ribonucleotide biosynthetic process GO:0009152 59 0.040
purine nucleotide metabolic process GO:0006163 302 0.040
regulation of endopeptidase activity GO:0052548 89 0.039
divalent inorganic cation homeostasis GO:0072507 138 0.039
cellular divalent inorganic cation homeostasis GO:0072503 127 0.039
regulation of hydrolase activity GO:0051336 246 0.038
positive regulation of apoptotic process GO:0043065 217 0.038
response to organonitrogen compound GO:0010243 246 0.037
mitochondrial calcium ion homeostasis GO:0051560 7 0.037
protein maturation GO:0051604 176 0.036
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.036
positive regulation of cell death GO:0010942 224 0.036
immune effector process GO:0002252 321 0.035
purine nucleoside biosynthetic process GO:0042451 19 0.034
regulation of cytokine production GO:0001817 266 0.034
response to endoplasmic reticulum stress GO:0034976 53 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.034
atp metabolic process GO:0046034 75 0.034
purine nucleoside monophosphate metabolic process GO:0009126 81 0.034
nicotinamide nucleotide biosynthetic process GO:0019359 4 0.034
cellular chemical homeostasis GO:0055082 215 0.034
nucleotide metabolic process GO:0009117 332 0.033
positive regulation of peptidase activity GO:0010952 49 0.033
cofactor transport GO:0051181 4 0.033
amine metabolic process GO:0009308 45 0.032
response to oxygen radical GO:0000305 16 0.032
cell adhesion GO:0007155 329 0.032
organic acid biosynthetic process GO:0016053 86 0.032
calcium ion homeostasis GO:0055074 127 0.032
response to inorganic substance GO:0010035 96 0.031
carbohydrate derivative biosynthetic process GO:1901137 183 0.030
purine ribonucleoside biosynthetic process GO:0046129 19 0.030
cytokine production GO:0001816 319 0.030
apoptotic mitochondrial changes GO:0008637 48 0.029
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
organic hydroxy compound metabolic process GO:1901615 203 0.029
regulation of t cell activation GO:0050863 170 0.029
purine nucleoside catabolic process GO:0006152 205 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.028
lymphocyte proliferation GO:0046651 164 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
intrinsic apoptotic signaling pathway GO:0097193 132 0.027
regulation of cell adhesion GO:0030155 154 0.027
cellular amine metabolic process GO:0044106 44 0.027
cellular respiration GO:0045333 38 0.027
cellularization GO:0007349 1 0.027
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.027
leukocyte proliferation GO:0070661 172 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
macromolecule catabolic process GO:0009057 281 0.027
regulation of lymphocyte activation GO:0051249 240 0.026
cellular calcium ion homeostasis GO:0006874 119 0.026
ribonucleotide biosynthetic process GO:0009260 59 0.026
translation GO:0006412 93 0.026
nucleoside biosynthetic process GO:0009163 21 0.026
ribonucleoside catabolic process GO:0042454 206 0.026
negative regulation of apoptotic signaling pathway GO:2001234 104 0.026
small molecule biosynthetic process GO:0044283 132 0.025
positive regulation of cell development GO:0010720 237 0.025
neuron apoptotic process GO:0051402 142 0.025
regulation of cell activation GO:0050865 289 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
heterocycle catabolic process GO:0046700 280 0.025
positive regulation of programmed cell death GO:0043068 218 0.025
regulation of cysteine type endopeptidase activity GO:2000116 65 0.025
positive regulation of cytokine production GO:0001819 174 0.025
alpha amino acid biosynthetic process GO:1901607 15 0.024
purine nucleotide biosynthetic process GO:0006164 65 0.024
carboxylic acid biosynthetic process GO:0046394 86 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
mitochondrion degradation GO:0000422 3 0.024
protein catabolic process GO:0030163 221 0.024
regulation of anatomical structure size GO:0090066 178 0.024
ribonucleoside monophosphate biosynthetic process GO:0009156 9 0.023
mitochondrial transport GO:0006839 36 0.023
nitrogen compound transport GO:0071705 271 0.023
myeloid cell differentiation GO:0030099 233 0.023
mitochondrial translation GO:0032543 4 0.023
locomotory behavior GO:0007626 195 0.023
positive regulation of hydrolase activity GO:0051345 148 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
anion transport GO:0006820 177 0.022
positive regulation of proteolysis GO:0045862 85 0.022
cell substrate adhesion GO:0031589 130 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
regulation of defense response GO:0031347 233 0.022
nucleoside monophosphate metabolic process GO:0009123 85 0.022
ribose phosphate biosynthetic process GO:0046390 59 0.022
cell type specific apoptotic process GO:0097285 268 0.022
immune response regulating signaling pathway GO:0002764 125 0.022
wound healing GO:0042060 157 0.022
gland development GO:0048732 330 0.021
methylation GO:0032259 134 0.021
innate immune response GO:0045087 157 0.021
divalent inorganic cation transport GO:0072511 178 0.020
spermatogenesis GO:0007283 284 0.020
dna metabolic process GO:0006259 303 0.020
membrane organization GO:0061024 245 0.020
action potential GO:0001508 78 0.020
regulation of protein transport GO:0051223 163 0.020
pyridine containing compound catabolic process GO:0072526 4 0.020
organic acid catabolic process GO:0016054 51 0.020
development of primary sexual characteristics GO:0045137 143 0.020
male gamete generation GO:0048232 285 0.020
positive regulation of lymphocyte activation GO:0051251 140 0.020
response to metal ion GO:0010038 47 0.020
organophosphate catabolic process GO:0046434 232 0.020
regulation of peptidase activity GO:0052547 96 0.020
leukocyte mediated immunity GO:0002443 174 0.020
purine nucleotide catabolic process GO:0006195 211 0.019
lipid biosynthetic process GO:0008610 179 0.019
regulation of cellular amine metabolic process GO:0033238 20 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
cellular response to lipid GO:0071396 145 0.019
cytoplasmic transport GO:0016482 234 0.019
activation of immune response GO:0002253 138 0.019
blood circulation GO:0008015 195 0.019
sensory perception GO:0007600 245 0.019
ras protein signal transduction GO:0007265 77 0.019
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
positive regulation of mitochondrion organization GO:0010822 17 0.019
divalent metal ion transport GO:0070838 172 0.019
homeostasis of number of cells GO:0048872 210 0.018
nucleoside catabolic process GO:0009164 206 0.018
glycosyl compound biosynthetic process GO:1901659 21 0.018
ribonucleoside monophosphate metabolic process GO:0009161 80 0.018
protein localization to mitochondrion GO:0070585 15 0.018
intracellular protein transport GO:0006886 204 0.018
cellular protein complex assembly GO:0043623 116 0.018
phagocytosis GO:0006909 66 0.018
regulation of proteolysis GO:0030162 164 0.018
synaptic transmission GO:0007268 329 0.018
protein targeting GO:0006605 143 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
engulfment of apoptotic cell GO:0043652 3 0.017
extracellular structure organization GO:0043062 148 0.017
nucleotide catabolic process GO:0009166 217 0.017
response to reactive oxygen species GO:0000302 56 0.017
extracellular matrix organization GO:0030198 147 0.017
b cell activation GO:0042113 161 0.017
leukocyte activation involved in immune response GO:0002366 126 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
regulation of body fluid levels GO:0050878 162 0.017
purine containing compound biosynthetic process GO:0072522 70 0.017
membrane fusion GO:0061025 38 0.017
positive regulation of cell adhesion GO:0045785 80 0.017
circulatory system process GO:0003013 197 0.017
positive regulation of cell activation GO:0050867 158 0.016
positive regulation of interferon alpha production GO:0032727 4 0.016
immune response activating signal transduction GO:0002757 116 0.016
lymphocyte mediated immunity GO:0002449 139 0.016
negative regulation of molecular function GO:0044092 258 0.016
endomembrane system organization GO:0010256 147 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.016
cellular response to dna damage stimulus GO:0006974 207 0.016
dephosphorylation GO:0016311 129 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
hepaticobiliary system development GO:0061008 67 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.015
glycoprotein metabolic process GO:0009100 116 0.015
cellular response to oxidative stress GO:0034599 76 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
regulation of hormone levels GO:0010817 211 0.015
membrane lipid biosynthetic process GO:0046467 32 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
germ cell development GO:0007281 185 0.015
regulation of interferon gamma production GO:0032649 57 0.015
regulation of cellular response to stress GO:0080135 159 0.015
negative regulation of immune system process GO:0002683 209 0.015
cell activation involved in immune response GO:0002263 126 0.015
positive regulation of endopeptidase activity GO:0010950 43 0.014
protein localization to organelle GO:0033365 185 0.014
b cell activation involved in immune response GO:0002312 50 0.014
regulation of ion transport GO:0043269 215 0.014
t cell proliferation GO:0042098 120 0.014
interferon gamma production GO:0032609 67 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
production of molecular mediator of immune response GO:0002440 103 0.014
sodium ion transport GO:0006814 73 0.014
pyridine nucleotide biosynthetic process GO:0019363 4 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
serine family amino acid metabolic process GO:0009069 7 0.014
zymogen activation GO:0031638 41 0.014
fatty acid elongation GO:0030497 3 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
peptide metabolic process GO:0006518 46 0.013
striated muscle tissue development GO:0014706 293 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
endoplasmic reticulum unfolded protein response GO:0030968 19 0.013
protein oligomerization GO:0051259 67 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.013
peptidyl amino acid modification GO:0018193 336 0.013
positive regulation of immune effector process GO:0002699 107 0.013
inflammatory response GO:0006954 244 0.013
regulation of neuron differentiation GO:0045664 281 0.013
positive regulation of apoptotic signaling pathway GO:2001235 95 0.013
alcohol metabolic process GO:0006066 116 0.013
skin development GO:0043588 220 0.013
multicellular organism growth GO:0035264 161 0.013
t cell differentiation GO:0030217 174 0.013
synapse organization GO:0050808 125 0.013
sphingolipid biosynthetic process GO:0030148 26 0.013
epidermis development GO:0008544 187 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
cell aging GO:0007569 35 0.013
positive regulation of innate immune response GO:0045089 80 0.013
cytokine production involved in immune response GO:0002367 34 0.013
calcium ion transport GO:0006816 159 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
trna metabolic process GO:0006399 11 0.013
trna aminoacylation GO:0043039 1 0.013
neuron death GO:0070997 154 0.012
regulation of peptide transport GO:0090087 91 0.012
vascular process in circulatory system GO:0003018 62 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
liver development GO:0001889 66 0.012
muscle cell differentiation GO:0042692 261 0.012
regulation of cell motility GO:2000145 236 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
regulation of mitochondrial fission GO:0090140 3 0.012
glutamate biosynthetic process GO:0006537 2 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
pigment biosynthetic process GO:0046148 26 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
innate immune response activating signal transduction GO:0002758 50 0.012
regulation of metal ion transport GO:0010959 106 0.012
sequestering of calcium ion GO:0051208 18 0.012
regulation of response to wounding GO:1903034 189 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
ossification GO:0001503 216 0.012
cellular amino acid biosynthetic process GO:0008652 22 0.012
response to extracellular stimulus GO:0009991 127 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
single organism cell adhesion GO:0098602 156 0.011
chromatin organization GO:0006325 206 0.011
steroid biosynthetic process GO:0006694 47 0.011
response to oxygen levels GO:0070482 62 0.011
dicarboxylic acid catabolic process GO:0043649 2 0.011
regulation of tube size GO:0035150 57 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
regulation of cell cycle GO:0051726 281 0.011
cellular lipid metabolic process GO:0044255 323 0.011
regulation of cell projection organization GO:0031344 206 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
blood vessel morphogenesis GO:0048514 285 0.011
lymphocyte differentiation GO:0030098 242 0.011
sequestering of metal ion GO:0051238 19 0.011
carbohydrate homeostasis GO:0033500 128 0.011
regulation of inflammatory response GO:0050727 147 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
gonad development GO:0008406 141 0.011
protein secretion GO:0009306 111 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
regulation of homeostatic process GO:0032844 182 0.011
response to nutrient levels GO:0031667 109 0.011
regulation of leukocyte mediated immunity GO:0002703 104 0.011
b cell proliferation GO:0042100 53 0.011
regulation of secretion by cell GO:1903530 249 0.011
release of cytochrome c from mitochondria GO:0001836 23 0.011
nuclear transport GO:0051169 139 0.011
anatomical structure homeostasis GO:0060249 145 0.011
positive regulation of macrophage activation GO:0043032 10 0.011
regulation of intracellular transport GO:0032386 159 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
regulation of secretion GO:0051046 274 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
very long chain fatty acid biosynthetic process GO:0042761 2 0.011
positive regulation of nervous system development GO:0051962 221 0.011
genitalia development GO:0048806 37 0.010
regulation of feeding behavior GO:0060259 3 0.010
pharynx development GO:0060465 1 0.010
kidney development GO:0001822 213 0.010
purine containing compound catabolic process GO:0072523 213 0.010
transition metal ion homeostasis GO:0055076 54 0.010
amp metabolic process GO:0046033 4 0.010
adaptive immune response GO:0002250 155 0.010
mitochondrial protein processing GO:0034982 5 0.010
gtp metabolic process GO:0046039 144 0.010
chromatin modification GO:0016568 187 0.010
carbohydrate metabolic process GO:0005975 230 0.010
regulation of mitochondrial translation GO:0070129 3 0.010
forebrain development GO:0030900 302 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.010
protein refolding GO:0042026 1 0.010
defense response to other organism GO:0098542 197 0.010
response to peptide hormone GO:0043434 127 0.010
mrna metabolic process GO:0016071 84 0.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.010
peptide transport GO:0015833 133 0.010
response to peptide GO:1901652 136 0.010
fatty acid biosynthetic process GO:0006633 41 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010

Lap3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.094
inherited metabolic disorder DOID:655 0 0.081
amino acid metabolic disorder DOID:9252 0 0.081
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.039
immune system disease DOID:2914 0 0.013
sensory system disease DOID:0050155 0 0.013
hematopoietic system disease DOID:74 0 0.011