Mus musculus

64 known processes

Lemd2

LEM domain containing 2

(Aliases: Lem2,NET25,BC026588,MGC37253)

Lemd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.501
modification dependent protein catabolic process GO:0019941 133 0.480
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.434
cellular macromolecule catabolic process GO:0044265 206 0.431
modification dependent macromolecule catabolic process GO:0043632 133 0.417
cellular protein catabolic process GO:0044257 155 0.344
proteasomal protein catabolic process GO:0010498 98 0.233
protein catabolic process GO:0030163 221 0.220
protein ubiquitination GO:0016567 171 0.199
regulation of cellular ketone metabolic process GO:0010565 66 0.189
cellular ketone metabolic process GO:0042180 84 0.169
ribose phosphate metabolic process GO:0019693 291 0.103
protein modification by small protein conjugation GO:0032446 187 0.095
i kappab kinase nf kappab signaling GO:0007249 85 0.086
ribonucleotide metabolic process GO:0009259 291 0.086
amine metabolic process GO:0009308 45 0.084
protein modification by small protein conjugation or removal GO:0070647 207 0.084
leukocyte differentiation GO:0002521 342 0.084
ubiquitin dependent protein catabolic process GO:0006511 129 0.080
intracellular protein transport GO:0006886 204 0.076
regulation of cellular catabolic process GO:0031329 242 0.075
chromatin modification GO:0016568 187 0.074
heart morphogenesis GO:0003007 178 0.072
peptidyl amino acid modification GO:0018193 336 0.069
positive regulation of cellular amine metabolic process GO:0033240 5 0.066
regulation of cellular amine metabolic process GO:0033238 20 0.064
cellular amine metabolic process GO:0044106 44 0.064
multi multicellular organism process GO:0044706 109 0.062
protein autophosphorylation GO:0046777 61 0.062
protein localization to organelle GO:0033365 185 0.059
antimicrobial peptide production GO:0002775 2 0.056
neurotransmitter secretion GO:0007269 62 0.056
regulation of cellular response to stress GO:0080135 159 0.055
response to molecule of bacterial origin GO:0002237 143 0.054
nucleoside phosphate metabolic process GO:0006753 338 0.053
neurotransmitter transport GO:0006836 76 0.051
purine ribonucleotide metabolic process GO:0009150 290 0.051
rhythmic process GO:0048511 174 0.051
positive regulation of protein modification process GO:0031401 299 0.050
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
glycosyl compound metabolic process GO:1901657 246 0.049
stress activated mapk cascade GO:0051403 80 0.049
cardiac chamber morphogenesis GO:0003206 93 0.048
positive regulation of cellular catabolic process GO:0031331 148 0.047
cytoplasmic transport GO:0016482 234 0.047
embryonic placenta development GO:0001892 98 0.047
regulation of secretion GO:0051046 274 0.046
stem cell development GO:0048864 219 0.045
cellular amino acid metabolic process GO:0006520 103 0.045
negative regulation of phosphorus metabolic process GO:0010563 184 0.045
sensory perception GO:0007600 245 0.044
regulation of secretion by cell GO:1903530 249 0.043
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.042
cardiac ventricle development GO:0003231 83 0.042
cytokine production GO:0001816 319 0.042
ras protein signal transduction GO:0007265 77 0.042
stem cell proliferation GO:0072089 117 0.042
regulation of membrane potential GO:0042391 192 0.041
positive regulation of protein phosphorylation GO:0001934 242 0.040
negative regulation of immune system process GO:0002683 209 0.039
purine nucleotide metabolic process GO:0006163 302 0.038
g protein coupled receptor signaling pathway GO:0007186 243 0.038
carbohydrate metabolic process GO:0005975 230 0.037
response to light stimulus GO:0009416 135 0.037
macromolecule catabolic process GO:0009057 281 0.037
cardiac chamber development GO:0003205 108 0.036
regulation of organelle organization GO:0033043 289 0.036
nucleotide metabolic process GO:0009117 332 0.035
neuron migration GO:0001764 122 0.035
organophosphate biosynthetic process GO:0090407 122 0.035
compound eye development GO:0048749 1 0.034
transmembrane transport GO:0055085 412 0.034
microtubule based process GO:0007017 236 0.034
regulation of hormone levels GO:0010817 211 0.034
regulation of cytokine production GO:0001817 266 0.034
cellular homeostasis GO:0019725 240 0.034
regulation of neurotransmitter levels GO:0001505 87 0.034
respiratory system development GO:0060541 190 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.033
metal ion homeostasis GO:0055065 189 0.033
spermatogenesis GO:0007283 284 0.033
negative regulation of growth GO:0045926 99 0.033
cation transport GO:0006812 399 0.032
regionalization GO:0003002 337 0.032
protein localization to nucleus GO:0034504 121 0.032
cardiac muscle tissue development GO:0048738 130 0.031
sterol homeostasis GO:0055092 45 0.031
cellular chemical homeostasis GO:0055082 215 0.031
prostate glandular acinus development GO:0060525 12 0.031
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
positive regulation of transferase activity GO:0051347 167 0.030
male gamete generation GO:0048232 285 0.030
purine containing compound metabolic process GO:0072521 311 0.030
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.030
immune response regulating signaling pathway GO:0002764 125 0.030
ribonucleoside metabolic process GO:0009119 245 0.030
stem cell differentiation GO:0048863 268 0.030
striated muscle tissue development GO:0014706 293 0.030
apoptotic signaling pathway GO:0097190 306 0.029
cation transmembrane transport GO:0098655 266 0.029
transcription from rna polymerase iii promoter GO:0006383 3 0.029
purine nucleoside catabolic process GO:0006152 205 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
cellular response to fluid shear stress GO:0071498 4 0.029
regulation of neuron projection development GO:0010975 169 0.029
photoreceptor cell differentiation GO:0046530 52 0.029
nitrogen compound transport GO:0071705 271 0.029
maintenance of location GO:0051235 89 0.029
positive regulation of neuron differentiation GO:0045666 141 0.029
circadian rhythm GO:0007623 114 0.028
mapk cascade GO:0000165 281 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.028
regulation of protein catabolic process GO:0042176 108 0.027
positive regulation of cell development GO:0010720 237 0.027
digestive system development GO:0055123 200 0.027
histone modification GO:0016570 159 0.027
purine nucleoside triphosphate metabolic process GO:0009144 226 0.027
membrane organization GO:0061024 245 0.027
ossification GO:0001503 216 0.026
positive regulation of protein catabolic process GO:0045732 60 0.026
cell type specific apoptotic process GO:0097285 268 0.026
positive regulation of map kinase activity GO:0043406 84 0.026
placenta development GO:0001890 140 0.026
multicellular organism growth GO:0035264 161 0.026
exocytosis GO:0006887 121 0.026
regulation of defense response GO:0031347 233 0.026
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.026
protein localization to membrane GO:0072657 108 0.026
cellular response to biotic stimulus GO:0071216 92 0.026
muscle tissue development GO:0060537 308 0.026
methylation GO:0032259 134 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
regulation of cellular amino acid metabolic process GO:0006521 5 0.025
cellular lipid metabolic process GO:0044255 323 0.025
glycosyl compound catabolic process GO:1901658 206 0.025
regulation of protein transport GO:0051223 163 0.024
multicellular organismal signaling GO:0035637 91 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
regulation of cell cycle GO:0051726 281 0.024
establishment of protein localization to organelle GO:0072594 118 0.023
cellular transition metal ion homeostasis GO:0046916 32 0.023
gtp metabolic process GO:0046039 144 0.023
protein targeting GO:0006605 143 0.023
cellular response to lipid GO:0071396 145 0.023
positive regulation of protein kinase activity GO:0045860 144 0.023
cellular ion homeostasis GO:0006873 165 0.023
ion transmembrane transport GO:0034220 361 0.023
positive regulation of nervous system development GO:0051962 221 0.022
synaptic transmission GO:0007268 329 0.022
single organism nuclear import GO:1902593 95 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.022
positive regulation of cholesterol homeostasis GO:2000189 2 0.022
response to lipopolysaccharide GO:0032496 128 0.022
chemotaxis GO:0006935 247 0.022
guanosine containing compound catabolic process GO:1901069 144 0.021
positive regulation of translational initiation GO:0045948 4 0.021
immune response activating signal transduction GO:0002757 116 0.021
action potential GO:0001508 78 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
ameboidal type cell migration GO:0001667 128 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
positive regulation of ral gtpase activity GO:0032852 4 0.021
regulation of cell activation GO:0050865 289 0.021
regulation of leukocyte differentiation GO:1902105 159 0.021
organelle localization GO:0051640 179 0.021
dephosphorylation GO:0016311 129 0.021
positive regulation of dna templated transcription elongation GO:0032786 2 0.020
regulation of protein targeting GO:1903533 61 0.020
regulation of hydrolase activity GO:0051336 246 0.020
regulation of embryonic development GO:0045995 71 0.020
peptidyl serine modification GO:0018209 83 0.020
regulation of multi organism process GO:0043900 111 0.020
regulation of vesicle mediated transport GO:0060627 139 0.020
gastrulation GO:0007369 116 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
locomotory behavior GO:0007626 195 0.020
positive regulation of mapk cascade GO:0043410 170 0.020
regulation of binding GO:0051098 111 0.020
ear development GO:0043583 200 0.020
regulation of cell adhesion GO:0030155 154 0.020
purine containing compound catabolic process GO:0072523 213 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.019
fertilization GO:0009566 127 0.019
positive regulation of cell projection organization GO:0031346 95 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
nucleoside catabolic process GO:0009164 206 0.019
negative regulation of molecular function GO:0044092 258 0.019
t cell differentiation GO:0030217 174 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
negative regulation of protein localization to nucleus GO:1900181 23 0.019
alpha beta t cell differentiation GO:0046632 69 0.018
negative regulation of cytokine production GO:0001818 84 0.018
regulation of histone methylation GO:0031060 30 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
regulation of chromosome organization GO:0033044 83 0.018
regulation of canonical wnt signaling pathway GO:0060828 82 0.018
mitotic cell cycle GO:0000278 195 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.018
development of primary sexual characteristics GO:0045137 143 0.018
central nervous system neuron differentiation GO:0021953 162 0.018
nucleotide biosynthetic process GO:0009165 78 0.018
regulation of purine nucleotide catabolic process GO:0033121 122 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
regulation of cell motility GO:2000145 236 0.018
blood vessel morphogenesis GO:0048514 285 0.017
inner ear receptor cell differentiation GO:0060113 61 0.017
regulation of histone modification GO:0031056 56 0.017
alpha amino acid metabolic process GO:1901605 59 0.017
cardiac muscle tissue morphogenesis GO:0055008 44 0.017
regulation of intracellular transport GO:0032386 159 0.017
regulation of reproductive process GO:2000241 66 0.017
p38mapk cascade GO:0038066 4 0.017
detection of stimulus involved in sensory perception GO:0050906 44 0.017
regulation of ral protein signal transduction GO:0032485 4 0.017
regulation of ion transport GO:0043269 215 0.017
regulation of mitotic cell cycle GO:0007346 126 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
muscle cell differentiation GO:0042692 261 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.016
regulation of cell growth GO:0001558 91 0.016
cell differentiation involved in embryonic placenta development GO:0060706 26 0.016
establishment of organelle localization GO:0051656 122 0.016
response to radiation GO:0009314 165 0.016
multicellular organismal response to stress GO:0033555 62 0.016
regulation of fatty acid metabolic process GO:0019217 28 0.016
regulation of antimicrobial humoral response GO:0002759 3 0.016
regulation of cellular protein catabolic process GO:1903362 61 0.016
pattern recognition receptor signaling pathway GO:0002221 47 0.016
skin development GO:0043588 220 0.016
skeletal system development GO:0001501 356 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
trophoblast giant cell differentiation GO:0060707 15 0.016
heterocycle catabolic process GO:0046700 280 0.016
positive regulation of neuron projection development GO:0010976 79 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
positive regulation of organelle organization GO:0010638 128 0.016
placenta blood vessel development GO:0060674 31 0.016
transmission of nerve impulse GO:0019226 76 0.016
regulation of anatomical structure size GO:0090066 178 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
reactive oxygen species metabolic process GO:0072593 84 0.015
ral protein signal transduction GO:0032484 2 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
cell junction organization GO:0034330 77 0.015
response to pain GO:0048265 26 0.015
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.015
neuron death GO:0070997 154 0.015
skeletal system morphogenesis GO:0048705 203 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
forebrain development GO:0030900 302 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
t cell activation GO:0042110 289 0.015
urogenital system development GO:0001655 261 0.015
regulation of homeostatic process GO:0032844 182 0.015
regulation of neurotransmitter transport GO:0051588 35 0.015
regulation of proteasomal protein catabolic process GO:0061136 46 0.015
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.015
visual perception GO:0007601 52 0.015
rho protein signal transduction GO:0007266 32 0.015
nuclear import GO:0051170 95 0.015
cellularization GO:0007349 1 0.015
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.015
internal protein amino acid acetylation GO:0006475 42 0.015
negative regulation of defense response GO:0031348 77 0.014
norepinephrine transport GO:0015874 2 0.014
brain segmentation GO:0035284 3 0.014
positive regulation of cytokine production GO:0001819 174 0.014
regulation of engulfment of apoptotic cell GO:1901074 2 0.014
protein import into nucleus GO:0006606 95 0.014
protein import GO:0017038 101 0.014
regulation of neuron death GO:1901214 134 0.014
regulation of circadian rhythm GO:0042752 58 0.014
calcium ion transport GO:0006816 159 0.014
innate immune response GO:0045087 157 0.014
notch signaling pathway GO:0007219 71 0.014
regulation of translation GO:0006417 71 0.014
regulation of cell projection organization GO:0031344 206 0.014
cell growth GO:0016049 130 0.014
synaptic vesicle transport GO:0048489 57 0.014
nuclear transport GO:0051169 139 0.014
regulation of protein localization GO:0032880 231 0.014
negative regulation of multi organism process GO:0043901 68 0.014
negative regulation of hydrolase activity GO:0051346 71 0.014
toll like receptor signaling pathway GO:0002224 38 0.014
mitotic cell cycle process GO:1903047 159 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
glucose homeostasis GO:0042593 128 0.014
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.014
regulation of cardiac cell fate specification GO:2000043 1 0.014
positive regulation of secretion GO:0051047 130 0.013
mammary gland epithelium development GO:0061180 65 0.013
aromatic compound catabolic process GO:0019439 286 0.013
endocytosis GO:0006897 168 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
organic hydroxy compound transport GO:0015850 93 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
blood circulation GO:0008015 195 0.013
segmentation GO:0035282 93 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
rna processing GO:0006396 105 0.013
regulation of myeloid cell differentiation GO:0045637 96 0.013
ventricular septum development GO:0003281 42 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
detection of stimulus GO:0051606 84 0.013
epithelial cell proliferation GO:0050673 174 0.013
regulation of cell division GO:0051302 76 0.013
b cell activation GO:0042113 161 0.013
nucleoside phosphate biosynthetic process GO:1901293 79 0.013
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.013
lymphocyte differentiation GO:0030098 242 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.013
lung development GO:0030324 164 0.013
epithelium migration GO:0090132 63 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
response to endoplasmic reticulum stress GO:0034976 53 0.013
organophosphate catabolic process GO:0046434 232 0.013
dna metabolic process GO:0006259 303 0.013
endomembrane system organization GO:0010256 147 0.012
regulation of mammary gland epithelial cell proliferation GO:0033599 12 0.012
extracellular matrix organization GO:0030198 147 0.012
positive regulation of defense response GO:0031349 124 0.012
protein oligomerization GO:0051259 67 0.012
cerebral cortex development GO:0021987 86 0.012
regulation of osteoblast differentiation GO:0045667 67 0.012
hexose metabolic process GO:0019318 98 0.012
regulation of protein import into nucleus GO:0042306 52 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
cartilage development GO:0051216 140 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
cardiac septum morphogenesis GO:0060411 46 0.012
peptide transport GO:0015833 133 0.012
golgi vesicle transport GO:0048193 30 0.012
4 hydroxyproline metabolic process GO:0019471 5 0.012
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.012
response to oxidative stress GO:0006979 123 0.012
neuronal action potential GO:0019228 54 0.012
regulation of translational initiation GO:0006446 15 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
limb development GO:0060173 166 0.012
cardiac muscle cell proliferation GO:0060038 31 0.012
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.012
heart field specification GO:0003128 6 0.012
anatomical structure homeostasis GO:0060249 145 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
regulation of exocytosis GO:0017157 61 0.012
positive regulation of cell growth GO:0030307 33 0.011
defense response to other organism GO:0098542 197 0.011
regulation of ral gtpase activity GO:0032315 4 0.011
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.011
telencephalon development GO:0021537 186 0.011
habituation GO:0046959 3 0.011
positive regulation of growth GO:0045927 104 0.011
negative regulation of neuron differentiation GO:0045665 101 0.011
mitochondrion organization GO:0007005 134 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
developmental cell growth GO:0048588 84 0.011
lens development in camera type eye GO:0002088 62 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
regulation of innate immune response GO:0045088 91 0.011
peptide hormone secretion GO:0030072 109 0.011
establishment of meiotic spindle orientation GO:0051296 1 0.011
membrane fusion GO:0061025 38 0.011
ribonucleotide biosynthetic process GO:0009260 59 0.011
signal transduction in absence of ligand GO:0038034 55 0.011
vesicle organization GO:0016050 60 0.011
regulation of proteolysis GO:0030162 164 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
stem cell maintenance GO:0019827 130 0.011
translation GO:0006412 93 0.011
cardiac muscle cell differentiation GO:0055007 69 0.011
axon ensheathment GO:0008366 76 0.011
regulation of protein processing GO:0070613 96 0.011
epidermis development GO:0008544 187 0.011
carbohydrate homeostasis GO:0033500 128 0.011
negative regulation of cell activation GO:0050866 111 0.011
regulation of neuron differentiation GO:0045664 281 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
negative regulation of cell motility GO:2000146 61 0.011
cardiac septum development GO:0003279 59 0.011
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
respiratory tube development GO:0030323 167 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
cation homeostasis GO:0055080 212 0.010
acetylcholine transport GO:0015870 2 0.010
positive regulation of nucleotide catabolic process GO:0030813 88 0.010
cellular response to acid chemical GO:0071229 68 0.010
mechanoreceptor differentiation GO:0042490 67 0.010
adult locomotory behavior GO:0008344 91 0.010
wnt signaling pathway GO:0016055 188 0.010
inflammatory response GO:0006954 244 0.010
defense response to bacterium GO:0042742 119 0.010
regulation of protein binding GO:0043393 60 0.010
neuron apoptotic process GO:0051402 142 0.010
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.010
cell adhesion GO:0007155 329 0.010
response to copper ion GO:0046688 3 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
dna methylation GO:0006306 43 0.010
retrograde transport endosome to golgi GO:0042147 2 0.010
neural precursor cell proliferation GO:0061351 121 0.010
nucleoside metabolic process GO:0009116 246 0.010
cyclic nucleotide metabolic process GO:0009187 59 0.010

Lemd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org