Mus musculus

20 known processes

Lepre1

leprecan 1

(Aliases: Gros1,2410024C15Rik,P3H1)

Lepre1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein hydroxylation GO:0018126 4 0.560
Human Mouse
extracellular matrix organization GO:0030198 147 0.492
extracellular structure organization GO:0043062 148 0.464
glycoprotein metabolic process GO:0009100 116 0.249
peptidyl proline hydroxylation GO:0019511 3 0.156
Mouse
skeletal system development GO:0001501 356 0.132
Human
bone development GO:0060348 120 0.124
Human
collagen fibril organization GO:0030199 32 0.100
oxidation reduction process GO:0055114 342 0.066
monocarboxylic acid metabolic process GO:0032787 191 0.065
Mouse
cell adhesion GO:0007155 329 0.063
chondrocyte differentiation GO:0002062 72 0.063
connective tissue development GO:0061448 179 0.062
cartilage development GO:0051216 140 0.062
nucleotide sugar metabolic process GO:0009225 4 0.059
cellular amino acid metabolic process GO:0006520 103 0.057
Mouse
glycoprotein biosynthetic process GO:0009101 89 0.055
male gamete generation GO:0048232 285 0.055
Mouse
peptidyl proline modification GO:0018208 6 0.051
Mouse
spermatogenesis GO:0007283 284 0.048
Mouse
response to oxygen levels GO:0070482 62 0.041
membrane organization GO:0061024 245 0.040
regulation of cell adhesion GO:0030155 154 0.040
nucleobase containing small molecule metabolic process GO:0055086 352 0.039
endomembrane system organization GO:0010256 147 0.039
regulation of ossification GO:0030278 112 0.039
respiratory system development GO:0060541 190 0.038
basement membrane organization GO:0071711 8 0.037
skeletal system morphogenesis GO:0048705 203 0.037
apoptotic signaling pathway GO:0097190 306 0.037
nucleotide metabolic process GO:0009117 332 0.036
defense response to other organism GO:0098542 197 0.034
signal transduction in absence of ligand GO:0038034 55 0.034
renal system development GO:0072001 225 0.034
macromolecule catabolic process GO:0009057 281 0.033
cell matrix adhesion GO:0007160 68 0.032
ossification GO:0001503 216 0.031
glycosylation GO:0070085 62 0.031
organonitrogen compound biosynthetic process GO:1901566 192 0.030
sulfur compound biosynthetic process GO:0044272 37 0.030
respiratory tube development GO:0030323 167 0.029
digestive tract development GO:0048565 190 0.029
cytoplasmic transport GO:0016482 234 0.029
chondrocyte development GO:0002063 24 0.029
carbohydrate derivative biosynthetic process GO:1901137 183 0.028
urogenital system development GO:0001655 261 0.028
single organismal cell cell adhesion GO:0016337 131 0.028
response to oxidative stress GO:0006979 123 0.028
single organism cell adhesion GO:0098602 156 0.027
multicellular organismal macromolecule metabolic process GO:0044259 19 0.026
protein catabolic process GO:0030163 221 0.026
mesenchymal cell differentiation GO:0048762 107 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
endocytosis GO:0006897 168 0.025
protein glycosylation GO:0006486 55 0.024
alpha amino acid metabolic process GO:1901605 59 0.024
sensory perception GO:0007600 245 0.024
engulfment of apoptotic cell GO:0043652 3 0.024
chemotaxis GO:0006935 247 0.024
response to organic cyclic compound GO:0014070 198 0.024
axonogenesis GO:0007409 274 0.024
cellular response to organonitrogen compound GO:0071417 145 0.024
stem cell differentiation GO:0048863 268 0.023
stem cell development GO:0048864 219 0.023
proteoglycan biosynthetic process GO:0030166 20 0.023
fat cell differentiation GO:0045444 160 0.023
sulfur compound metabolic process GO:0006790 100 0.023
intrinsic apoptotic signaling pathway GO:0097193 132 0.022
purine containing compound metabolic process GO:0072521 311 0.022
sensory perception of mechanical stimulus GO:0050954 107 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
ameboidal type cell migration GO:0001667 128 0.021
organic acid transport GO:0015849 101 0.021
response to decreased oxygen levels GO:0036293 59 0.021
response to inorganic substance GO:0010035 96 0.021
amine metabolic process GO:0009308 45 0.021
small gtpase mediated signal transduction GO:0007264 97 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
cation transmembrane transport GO:0098655 266 0.020
macromolecule glycosylation GO:0043413 55 0.020
wnt signaling pathway GO:0016055 188 0.020
negative regulation of cell adhesion GO:0007162 45 0.020
transmembrane transport GO:0055085 412 0.020
muscle tissue development GO:0060537 308 0.020
organelle assembly GO:0070925 177 0.019
golgi vesicle transport GO:0048193 30 0.019
formation of primary germ layer GO:0001704 77 0.019
blood vessel morphogenesis GO:0048514 285 0.019
synaptic transmission GO:0007268 329 0.019
regulation of organelle organization GO:0033043 289 0.019
dna metabolic process GO:0006259 303 0.019
response to radiation GO:0009314 165 0.019
muscle cell differentiation GO:0042692 261 0.019
peptidyl amino acid modification GO:0018193 336 0.019
Mouse
response to organonitrogen compound GO:0010243 246 0.018
acetylcholine transport GO:0015870 2 0.018
rhythmic process GO:0048511 174 0.018
mitochondrion distribution GO:0048311 4 0.018
mesenchymal cell development GO:0014031 93 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
Human
positive regulation of cell motility GO:2000147 116 0.017
antibacterial peptide secretion GO:0002779 1 0.017
anion transport GO:0006820 177 0.017
regulation of cell migration GO:0030334 219 0.017
regulation of innate immune response GO:0045088 91 0.017
localization within membrane GO:0051668 4 0.017
camera type eye development GO:0043010 266 0.017
development of primary sexual characteristics GO:0045137 143 0.017
regulation of cellular ketone metabolic process GO:0010565 66 0.017
innate immune response GO:0045087 157 0.017
cellular ketone metabolic process GO:0042180 84 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.016
biomineral tissue development GO:0031214 64 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
interspecies interaction between organisms GO:0044419 83 0.016
antimicrobial peptide production GO:0002775 2 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
regulation of defense response GO:0031347 233 0.016
regulation of cell motility GO:2000145 236 0.016
cell growth GO:0016049 130 0.016
positive regulation of defense response GO:0031349 124 0.016
axon guidance GO:0007411 141 0.016
body morphogenesis GO:0010171 45 0.016
cellular modified amino acid metabolic process GO:0006575 63 0.015
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.015
lung development GO:0030324 164 0.015
positive regulation of innate immune response GO:0045089 80 0.015
digestive system development GO:0055123 200 0.015
basement membrane assembly GO:0070831 2 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
regulation of cytokine production GO:0001817 266 0.015
ion transmembrane transport GO:0034220 361 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
Human
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.015
peptide metabolic process GO:0006518 46 0.015
proteoglycan metabolic process GO:0006029 38 0.015
bone mineralization GO:0030282 54 0.015
bone morphogenesis GO:0060349 78 0.015
chromatin organization GO:0006325 206 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
regulation of neuron differentiation GO:0045664 281 0.014
sensory perception of sound GO:0007605 97 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
carbohydrate metabolic process GO:0005975 230 0.014
intracellular protein transport GO:0006886 204 0.014
regulation of mapk cascade GO:0043408 248 0.014
sensory perception of light stimulus GO:0050953 54 0.014
vesicle organization GO:0016050 60 0.014
tissue homeostasis GO:0001894 115 0.014
collagen metabolic process GO:0032963 17 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
regulation of cellular amino acid metabolic process GO:0006521 5 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
copii coated vesicle budding GO:0090114 2 0.013
gland development GO:0048732 330 0.013
fucosylation GO:0036065 9 0.013
regulation of cellular amine metabolic process GO:0033238 20 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
neuron migration GO:0001764 122 0.013
collagen biosynthetic process GO:0032964 7 0.013
maintenance of location GO:0051235 89 0.013
positive regulation of cell adhesion GO:0045785 80 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
organ growth GO:0035265 117 0.013
immune effector process GO:0002252 321 0.013
oocyte axis specification GO:0007309 2 0.013
cellular amine metabolic process GO:0044106 44 0.013
cellular response to acid chemical GO:0071229 68 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
gastrulation GO:0007369 116 0.013
defense response to bacterium GO:0042742 119 0.013
protein localization to organelle GO:0033365 185 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
positive regulation of proteolysis GO:0045862 85 0.013
response to acid chemical GO:0001101 111 0.013
response to endoplasmic reticulum stress GO:0034976 53 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
smoothened signaling pathway GO:0007224 105 0.012
protein localization to membrane GO:0072657 108 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
synapse organization GO:0050808 125 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
cellularization GO:0007349 1 0.012
head morphogenesis GO:0060323 34 0.012
neuron projection guidance GO:0097485 141 0.012
sensory organ morphogenesis GO:0090596 242 0.012
visual perception GO:0007601 52 0.012
positive regulation of cell death GO:0010942 224 0.012
ear morphogenesis GO:0042471 118 0.012
cellular response to lipid GO:0071396 145 0.012
organic anion transport GO:0015711 137 0.012
fertilization GO:0009566 127 0.012
regulation of blood vessel size GO:0050880 56 0.012
retina development in camera type eye GO:0060041 119 0.011
phagocytosis GO:0006909 66 0.011
ear development GO:0043583 200 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
defense response to virus GO:0051607 68 0.011
peptidyl proline hydroxylation to 4 hydroxy l proline GO:0018401 2 0.011
cytokinetic process GO:0032506 2 0.011
inflammatory response GO:0006954 244 0.011
response to light stimulus GO:0009416 135 0.011
learning or memory GO:0007611 148 0.011
nuclear transport GO:0051169 139 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
negative regulation of dna replication GO:0008156 4 0.011
forebrain development GO:0030900 302 0.011
regulation of multi organism process GO:0043900 111 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
nitrogen compound transport GO:0071705 271 0.011
muscle system process GO:0003012 141 0.011
cell chemotaxis GO:0060326 81 0.011
negative regulation of immune system process GO:0002683 209 0.011
negative regulation of nervous system development GO:0051961 156 0.011
appendage development GO:0048736 166 0.011
regulation of cellular response to oxidative stress GO:1900407 19 0.011
kidney development GO:0001822 213 0.011
multi multicellular organism process GO:0044706 109 0.010
response to hypoxia GO:0001666 58 0.010
antibacterial peptide biosynthetic process GO:0002780 2 0.010
anatomical structure homeostasis GO:0060249 145 0.010
regulation of response to oxidative stress GO:1902882 19 0.010
negative regulation of cellular component organization GO:0051129 194 0.010
positive regulation of apoptotic cell clearance GO:2000427 3 0.010
transition metal ion transport GO:0000041 38 0.010
acetate ester transport GO:1901374 2 0.010
peripheral nervous system axon regeneration GO:0014012 2 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010

Lepre1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.378
Human
musculoskeletal system disease DOID:17 0 0.378
Human
connective tissue disease DOID:65 0 0.378
Human
bone development disease DOID:0080006 0 0.108
Human
bone disease DOID:0080001 0 0.108
Human
osteochondrodysplasia DOID:2256 0 0.101
Human
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.022
muscular disease DOID:0080000 0 0.017
muscle tissue disease DOID:66 0 0.017
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
nervous system disease DOID:863 0 0.014