Mus musculus

263 known processes

Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

(Aliases: Gpr48,9130225G07,A930009A08Rik,A330106J01Rik)

Lgr4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ovarian follicle development GO:0001541 40 0.961
Mouse
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.917
morphogenesis of a branching epithelium GO:0061138 193 0.915
female sex differentiation GO:0046660 84 0.915
Mouse
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.871
carbohydrate metabolic process GO:0005975 230 0.870
Mouse
female gonad development GO:0008585 71 0.862
Mouse
epithelial tube morphogenesis GO:0060562 303 0.856
regulation of cell adhesion mediated by integrin GO:0033628 13 0.853
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.841
hormone metabolic process GO:0042445 86 0.841
Mouse
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.817
carbon catabolite activation of transcription GO:0045991 4 0.812
cellular carbohydrate metabolic process GO:0044262 119 0.806
Mouse
positive regulation of transcription by glucose GO:0046016 3 0.793
cellular modified amino acid metabolic process GO:0006575 63 0.782
pyramidal neuron migration GO:0021852 1 0.767
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.747
development of primary female sexual characteristics GO:0046545 73 0.741
Mouse
mesonephric epithelium development GO:0072163 94 0.733
ureteric bud development GO:0001657 94 0.724
regulation of vascular wound healing GO:0061043 2 0.722
gland development GO:0048732 330 0.706
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.706
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.705
branching morphogenesis of an epithelial tube GO:0048754 159 0.698
glycosaminoglycan metabolic process GO:0030203 34 0.690
mesenchyme development GO:0060485 152 0.689
Fly
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.687
kidney epithelium development GO:0072073 121 0.686
extracellular matrix organization GO:0030198 147 0.685
Mouse
regulation of inflammatory response GO:0050727 147 0.682
smoothened signaling pathway GO:0007224 105 0.680
prostate gland stromal morphogenesis GO:0060741 2 0.668
spermatogenesis GO:0007283 284 0.655
metanephric capsule morphogenesis GO:0072265 1 0.653
embryonic organ morphogenesis GO:0048562 276 0.640
Mouse
pattern specification involved in metanephros development GO:0072268 4 0.635
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.624
negative regulation of molecular function GO:0044092 258 0.618
mesonephric tubule development GO:0072164 94 0.606
lung development GO:0030324 164 0.604
renal tubule development GO:0061326 87 0.603
regulation of secretion by cell GO:1903530 249 0.581
regulation of glucose metabolic process GO:0010906 60 0.581
transcription from rna polymerase iii promoter GO:0006383 3 0.581
negative regulation of phosphorus metabolic process GO:0010563 184 0.580
regulation of tube size GO:0035150 57 0.575
hexose metabolic process GO:0019318 98 0.572
nephron epithelium morphogenesis GO:0072088 68 0.556
cellular amino acid metabolic process GO:0006520 103 0.556
regulation of exocytosis GO:0017157 61 0.555
regulation of defense response GO:0031347 233 0.552
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.550
activation of mapk activity involved in innate immune response GO:0035419 2 0.550
gonad development GO:0008406 141 0.542
Mouse
axon guidance GO:0007411 141 0.529
carbon catabolite regulation of transcription GO:0045990 4 0.527
stem cell development GO:0048864 219 0.526
Fly
response to extracellular stimulus GO:0009991 127 0.525
neuron projection guidance GO:0097485 141 0.523
wnt signaling pathway GO:0016055 188 0.515
blood circulation GO:0008015 195 0.514
Mouse
glomerulus development GO:0032835 40 0.513
negative regulation of phosphorylation GO:0042326 166 0.513
cytokine production GO:0001816 319 0.511
skeletal system morphogenesis GO:0048705 203 0.511
eosinophil migration GO:0072677 3 0.511
ureteric bud morphogenesis GO:0060675 62 0.511
regulation of blood vessel size GO:0050880 56 0.506
regulation of cytokine production GO:0001817 266 0.506
morphogenesis of a branching structure GO:0001763 203 0.504
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.504
regulation of response to wounding GO:1903034 189 0.487
vascular process in circulatory system GO:0003018 62 0.484
embryonic viscerocranium morphogenesis GO:0048703 8 0.480
carbon catabolite repression of transcription GO:0045013 1 0.473
immune effector process GO:0002252 321 0.473
appendage morphogenesis GO:0035107 149 0.462
urogenital system development GO:0001655 261 0.459
negative regulation of mast cell degranulation GO:0043305 4 0.458
adult behavior GO:0030534 135 0.456
Mouse
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.456
negative regulation of detection of glucose GO:2000971 1 0.451
cellular ketone metabolic process GO:0042180 84 0.449
cellular response to starvation GO:0009267 57 0.448
iris morphogenesis GO:0061072 2 0.441
paraxial mesodermal cell differentiation GO:0048342 2 0.440
bmp signaling pathway GO:0030509 93 0.439
granulosa cell differentiation GO:0060014 1 0.439
negative regulation of hexokinase activity GO:1903300 4 0.439
mesenchymal cell development GO:0014031 93 0.432
Fly
neuron migration GO:0001764 122 0.430
oxidation reduction process GO:0055114 342 0.430
negative regulation of glucokinase activity GO:0033132 4 0.428
regulation of secretion GO:0051046 274 0.428
hair follicle development GO:0001942 85 0.427
response to peptide hormone GO:0043434 127 0.426
response to organonitrogen compound GO:0010243 246 0.425
inner ear morphogenesis GO:0042472 101 0.424
Mouse
morphogenesis of a polarized epithelium GO:0001738 37 0.424
cell proliferation in hindbrain GO:0021534 10 0.422
cellular response to hormone stimulus GO:0032870 150 0.418
Mouse
extracellular matrix dependent thymocyte migration GO:0072680 1 0.413
immune response regulating signaling pathway GO:0002764 125 0.406
ovulation cycle GO:0042698 59 0.404
Mouse
camera type eye development GO:0043010 266 0.403
inflammatory response GO:0006954 244 0.402
axonogenesis GO:0007409 274 0.401
detection of glucose GO:0051594 1 0.401
lymphocyte differentiation GO:0030098 242 0.400
Mouse
cerebral cortex radially oriented cell migration GO:0021799 31 0.397
positive regulation of cell migration GO:0030335 109 0.395
monosaccharide metabolic process GO:0005996 106 0.393
female sex determination GO:0030237 1 0.391
cellular response to external stimulus GO:0071496 88 0.390
regulation of lipid metabolic process GO:0019216 118 0.378
Mouse
regulation of transcription from rna polymerase ii promoter by glucose GO:0000430 3 0.378
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.377
Mouse
organ growth GO:0035265 117 0.376
detection of stimulus GO:0051606 84 0.374
male sex differentiation GO:0046661 109 0.371
inner ear receptor cell differentiation GO:0060113 61 0.370
Mouse
thyroid hormone metabolic process GO:0042403 16 0.369
single organismal cell cell adhesion GO:0016337 131 0.368
negative regulation of cell proliferation GO:0008285 296 0.365
thyroid hormone generation GO:0006590 7 0.363
regulation of hormone secretion GO:0046883 88 0.362
regulation of mast cell activation GO:0033003 21 0.359
activation of innate immune response GO:0002218 56 0.358
regionalization GO:0003002 337 0.357
kidney development GO:0001822 213 0.356
positive regulation of response to wounding GO:1903036 66 0.354
establishment of planar polarity GO:0001736 28 0.353
digestive system development GO:0055123 200 0.350
response to starvation GO:0042594 65 0.348
regulation of cell adhesion GO:0030155 154 0.347
paraxial mesodermal cell fate commitment GO:0048343 2 0.347
embryonic skeletal system development GO:0048706 120 0.345
aminoglycan metabolic process GO:0006022 34 0.342
glomerular mesangial cell differentiation GO:0072008 3 0.336
cellular response to nutrient levels GO:0031669 64 0.335
spinal cord motor neuron migration GO:0097476 4 0.335
circulatory system process GO:0003013 197 0.333
Mouse
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.331
adult locomotory behavior GO:0008344 91 0.327
Mouse
multicellular organism growth GO:0035264 161 0.326
Mouse
regulation of homeostatic process GO:0032844 182 0.320
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.317
leukocyte activation involved in immune response GO:0002366 126 0.317
nucleoside phosphate metabolic process GO:0006753 338 0.316
Mouse
respiratory system development GO:0060541 190 0.316
lung lobe morphogenesis GO:0060463 9 0.316
activation of immune response GO:0002253 138 0.315
limb morphogenesis GO:0035108 149 0.315
ion transmembrane transport GO:0034220 361 0.314
epithelial cell differentiation involved in prostate gland development GO:0060742 13 0.313
regulation of purine nucleotide metabolic process GO:1900542 169 0.312
Mouse
endocrine system development GO:0035270 98 0.312
mesenchymal cell differentiation GO:0048762 107 0.308
Fly
regulation of transcription by glucose GO:0046015 3 0.307
cell adhesion mediated by integrin GO:0033627 18 0.307
steroid metabolic process GO:0008202 119 0.305
Mouse
regulation of intracellular transport GO:0032386 159 0.304
metanephric capsule development GO:0072213 1 0.302
mesangial cell differentiation GO:0072007 4 0.295
neural tube development GO:0021915 160 0.293
response to peptide GO:1901652 136 0.290
positive regulation of cell motility GO:2000147 116 0.289
embryonic skeletal system morphogenesis GO:0048704 91 0.288
ear development GO:0043583 200 0.287
Mouse
vascular wound healing GO:0061042 3 0.287
nephrogenic mesenchyme development GO:0072076 3 0.286
canonical wnt signaling pathway GO:0060070 130 0.280
kidney morphogenesis GO:0060993 83 0.280
regulation of transporter activity GO:0032409 57 0.278
tissue remodeling GO:0048771 102 0.278
renal capsule specification GO:0072130 1 0.278
negative regulation of neuron death GO:1901215 98 0.276
renal capsule development GO:0072127 1 0.275
telencephalon development GO:0021537 186 0.275
positive regulation of apoptotic process GO:0043065 217 0.275
digestive tract development GO:0048565 190 0.274
amine metabolic process GO:0009308 45 0.272
Mouse
negative regulation of transcription by glucose GO:0045014 1 0.271
cation transport GO:0006812 399 0.271
sensory organ morphogenesis GO:0090596 242 0.270
Mouse
positive regulation of cell adhesion GO:0045785 80 0.267
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.266
epidermis development GO:0008544 187 0.266
regulation of mast cell activation involved in immune response GO:0033006 17 0.264
myeloid leukocyte activation GO:0002274 83 0.264
chromatin modification GO:0016568 187 0.262
Mouse
somitogenesis GO:0001756 69 0.261
regulation of organelle organization GO:0033043 289 0.259
Mouse
leukocyte mediated immunity GO:0002443 174 0.258
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.258
regulation of protein transport GO:0051223 163 0.257
regulation of cellular amine metabolic process GO:0033238 20 0.257
Mouse
regulation of steroid metabolic process GO:0019218 39 0.256
Mouse
cellular homeostasis GO:0019725 240 0.256
Mouse
transmembrane transport GO:0055085 412 0.254
lipid biosynthetic process GO:0008610 179 0.253
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.251
regulation of bmp signaling pathway GO:0030510 60 0.251
mesenchyme morphogenesis GO:0072132 32 0.249
nephron tubule morphogenesis GO:0072078 68 0.248
skeletal muscle organ development GO:0060538 163 0.247
cardiac chamber morphogenesis GO:0003206 93 0.246
negative regulation of growth GO:0045926 99 0.245
positive regulation of nervous system development GO:0051962 221 0.245
apoptotic signaling pathway GO:0097190 306 0.244
positive regulation of cellular catabolic process GO:0031331 148 0.240
cell cell junction organization GO:0045216 72 0.240
chemotaxis GO:0006935 247 0.238
positive regulation of apoptotic signaling pathway GO:2001235 95 0.237
macromolecule catabolic process GO:0009057 281 0.236
cellular lipid metabolic process GO:0044255 323 0.235
metanephros development GO:0001656 79 0.235
regulation of organ morphogenesis GO:2000027 144 0.233
regulation of lymphocyte proliferation GO:0050670 117 0.230
heart morphogenesis GO:0003007 178 0.228
regulation of regulated secretory pathway GO:1903305 20 0.227
regulation of t cell proliferation GO:0042129 92 0.227
maintenance of location GO:0051235 89 0.226
nephron morphogenesis GO:0072028 69 0.225
cerebral cortex radial glia guided migration GO:0021801 17 0.224
hindbrain development GO:0030902 128 0.223
locomotory behavior GO:0007626 195 0.222
Mouse
pallium development GO:0021543 120 0.221
lateral mesodermal cell differentiation GO:0048371 3 0.220
mast cell activation GO:0045576 27 0.219
renal capsule formation GO:0072129 1 0.217
neuron death GO:0070997 154 0.217
negative regulation of cell development GO:0010721 169 0.217
mitochondrion organization GO:0007005 134 0.216
ear morphogenesis GO:0042471 118 0.214
Mouse
nitrogen compound transport GO:0071705 271 0.213
paraxial mesoderm morphogenesis GO:0048340 10 0.213
regulation of cell migration GO:0030334 219 0.213
gonad morphogenesis GO:0035262 1 0.213
protein processing GO:0016485 163 0.211
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.211
response to radiation GO:0009314 165 0.211
cellular response to cytokine stimulus GO:0071345 189 0.210
response to nutrient levels GO:0031667 109 0.209
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.205
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.201
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.201
segmentation GO:0035282 93 0.200
lymphocyte homeostasis GO:0002260 64 0.199
epithelial cell differentiation involved in mammary gland alveolus development GO:0061030 4 0.199
regulation of leukocyte mediated immunity GO:0002703 104 0.198
metanephric capsule specification GO:0072267 1 0.197
regulation of apoptotic signaling pathway GO:2001233 197 0.197
nephron epithelium development GO:0072009 92 0.195
spermatid differentiation GO:0048515 115 0.195
Mouse
regulation of ion transport GO:0043269 215 0.194
central nervous system neuron development GO:0021954 67 0.193
glomerular endothelium development GO:0072011 2 0.193
organonitrogen compound biosynthetic process GO:1901566 192 0.192
Mouse
renal tubule morphogenesis GO:0061333 72 0.191
collagen fibril organization GO:0030199 32 0.191
response to alcohol GO:0097305 48 0.191
myelination in peripheral nervous system GO:0022011 19 0.190
photoreceptor cell fate commitment GO:0046552 2 0.190
regulation of lymphocyte activation GO:0051249 240 0.190
positive regulation of lymphocyte activation GO:0051251 140 0.190
peptidyl amino acid modification GO:0018193 336 0.190
cerebellar purkinje cell layer development GO:0021680 26 0.189
negative regulation of immune system process GO:0002683 209 0.188
positive regulation of epidermal growth factor activated receptor activity GO:0045741 2 0.186
regulation of cell activation GO:0050865 289 0.186
regulation of cellular response to stress GO:0080135 159 0.184
regulation of cell motility GO:2000145 236 0.182
cardiac septum morphogenesis GO:0060411 46 0.182
regulation of canonical wnt signaling pathway GO:0060828 82 0.180
glucose metabolic process GO:0006006 92 0.180
prostate glandular acinus development GO:0060525 12 0.179
mesoderm development GO:0007498 100 0.176
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.175
Mouse
digestive tract morphogenesis GO:0048546 147 0.174
somatic sex determination GO:0018993 2 0.173
cellular chemical homeostasis GO:0055082 215 0.170
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.170
neuron apoptotic process GO:0051402 142 0.170
positive regulation of innate immune response GO:0045089 80 0.170
hair cycle GO:0042633 90 0.168
purine containing compound metabolic process GO:0072521 311 0.167
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.166
phenol containing compound metabolic process GO:0018958 60 0.165
pancreas development GO:0031016 57 0.164
epithelial cell morphogenesis GO:0003382 41 0.164
negative regulation of cell activation GO:0050866 111 0.162
ventricular septum morphogenesis GO:0060412 27 0.161
female somatic sex determination GO:0019101 1 0.160
divalent metal ion transport GO:0070838 172 0.160
response to insulin GO:0032868 100 0.159
regulation of leukocyte differentiation GO:1902105 159 0.159
Mouse
response to growth factor GO:0070848 198 0.158
carbohydrate biosynthetic process GO:0016051 74 0.158
Mouse
regulation of embryonic development GO:0045995 71 0.158
establishment of protein localization to organelle GO:0072594 118 0.157
epithelial cell differentiation involved in kidney development GO:0035850 23 0.157
cellular response to organic cyclic compound GO:0071407 87 0.157
positive regulation of protein modification process GO:0031401 299 0.156
lateral mesoderm morphogenesis GO:0048369 3 0.154
regulation of establishment of protein localization GO:0070201 181 0.154
myelination GO:0042552 74 0.153
positive regulation of endothelial cell migration GO:0010595 12 0.151
endomembrane system organization GO:0010256 147 0.151
embryonic camera type eye development GO:0031076 36 0.151
tissue migration GO:0090130 68 0.151
skin development GO:0043588 220 0.150
angiogenesis GO:0001525 201 0.150
regulation of neuron death GO:1901214 134 0.148
spermatid development GO:0007286 108 0.147
Mouse
cell type specific apoptotic process GO:0097285 268 0.146
regulation of wound healing GO:0061041 40 0.146
regulation of cellular catabolic process GO:0031329 242 0.144
sulfur compound metabolic process GO:0006790 100 0.144
positive regulation of stem cell proliferation GO:2000648 59 0.144
regulation of cellular ketone metabolic process GO:0010565 66 0.143
protein localization to organelle GO:0033365 185 0.143
negative regulation of inflammatory response GO:0050728 61 0.142
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 0.142
signal transduction in absence of ligand GO:0038034 55 0.142
protein secretion GO:0009306 111 0.142
mitotic cell cycle GO:0000278 195 0.141
neural precursor cell proliferation GO:0061351 121 0.140
positive regulation of leukocyte differentiation GO:1902107 86 0.140
negative regulation of defense response GO:0031348 77 0.140
gastrulation GO:0007369 116 0.140
mapk cascade GO:0000165 281 0.140
Mouse
regulation of t cell activation GO:0050863 170 0.140
hormone secretion GO:0046879 128 0.139
regulation of mast cell degranulation GO:0043304 16 0.139
male gamete generation GO:0048232 285 0.138
lymphocyte apoptotic process GO:0070227 54 0.138
epithelial cell proliferation GO:0050673 174 0.137
leukocyte differentiation GO:0002521 342 0.137
Mouse
response to light stimulus GO:0009416 135 0.137
negative regulation of cellular carbohydrate metabolic process GO:0010677 19 0.136
muscle tissue development GO:0060537 308 0.136
mesoderm morphogenesis GO:0048332 64 0.136
negative regulation of kinase activity GO:0033673 81 0.136
regulation of myeloid leukocyte differentiation GO:0002761 58 0.136
Mouse
mesonephric tubule morphogenesis GO:0072171 63 0.135
lateral mesoderm formation GO:0048370 3 0.135
regulation of cytoplasmic transport GO:1903649 112 0.134
formation of primary germ layer GO:0001704 77 0.133
development of primary sexual characteristics GO:0045137 143 0.133
Mouse
negative regulation of protein modification process GO:0031400 163 0.132
metanephric tubule development GO:0072170 18 0.132
regulation of anatomical structure size GO:0090066 178 0.131
cellular response to extracellular stimulus GO:0031668 81 0.131
regulation of protein localization GO:0032880 231 0.131
negative regulation of response to wounding GO:1903035 77 0.130
regulation of mapk cascade GO:0043408 248 0.130
Mouse
telencephalon cell migration GO:0022029 55 0.129
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.128
metanephric capsule formation GO:0072266 1 0.128
closure of optic fissure GO:0061386 2 0.128
regulation of stem cell proliferation GO:0072091 78 0.128
microtubule based process GO:0007017 236 0.127
positive regulation of leukocyte apoptotic process GO:2000108 21 0.127
cell substrate adhesion GO:0031589 130 0.127
detection of monosaccharide stimulus GO:0034287 1 0.126
regulation of intracellular protein transport GO:0033157 82 0.126
positive regulation of defense response GO:0031349 124 0.125
regulation of hydrolase activity GO:0051336 246 0.124
regulation of transferase activity GO:0051338 263 0.124
positive regulation of neural precursor cell proliferation GO:2000179 42 0.124
cellular amine metabolic process GO:0044106 44 0.124
Mouse
regulation of t cell differentiation GO:0045580 83 0.124
neuromuscular process controlling balance GO:0050885 59 0.123
cardiac muscle tissue development GO:0048738 130 0.123
divalent inorganic cation homeostasis GO:0072507 138 0.123
glycoprotein biosynthetic process GO:0009101 89 0.122
development of primary male sexual characteristics GO:0046546 88 0.122
Mouse
regulation of neuron projection development GO:0010975 169 0.122
metal ion homeostasis GO:0055065 189 0.122
cell adhesion GO:0007155 329 0.122
negative regulation of cellular protein metabolic process GO:0032269 247 0.122
positive regulation of cell death GO:0010942 224 0.121
renal capsule morphogenesis GO:0072128 1 0.121
cellular response to insulin stimulus GO:0032869 78 0.120
lymphocyte proliferation GO:0046651 164 0.120
epithelial mesenchymal signaling involved in prostate gland development GO:0060738 2 0.120
regulation of carbohydrate metabolic process GO:0006109 75 0.120
Mouse
negative regulation of interleukin 8 production GO:0032717 1 0.120
prostate gland morphogenesis GO:0060512 32 0.120
central nervous system neuron differentiation GO:0021953 162 0.119
carbohydrate derivative biosynthetic process GO:1901137 183 0.119
Mouse
fibronectin dependent thymocyte migration GO:0072681 1 0.119
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.119
negative regulation of epithelial cell proliferation GO:0050680 64 0.119
prostate gland development GO:0030850 48 0.119
regulation of protein secretion GO:0050708 82 0.118
regulation of map kinase activity GO:0043405 120 0.117
negative regulation of neuron differentiation GO:0045665 101 0.117
regulation of smoothened signaling pathway GO:0008589 58 0.117
somite development GO:0061053 81 0.116
regulation of vasculature development GO:1901342 88 0.115
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.115
negative regulation of intracellular signal transduction GO:1902532 167 0.114
regulation of membrane potential GO:0042391 192 0.114
striated muscle cell proliferation GO:0014855 39 0.114
blood vessel morphogenesis GO:0048514 285 0.113
ribonucleotide metabolic process GO:0009259 291 0.113
Mouse
gliogenesis GO:0042063 141 0.113
pituitary gland development GO:0021983 38 0.112
establishment of tissue polarity GO:0007164 28 0.112
negative regulation of transferase activity GO:0051348 85 0.112
regulation of multi organism process GO:0043900 111 0.111
peptide transport GO:0015833 133 0.111
leukocyte migration GO:0050900 124 0.111
dichotomous subdivision of terminal units involved in ureteric bud branching GO:0060678 1 0.111
calcium ion homeostasis GO:0055074 127 0.110
cerebellum development GO:0021549 77 0.110
mast cell degranulation GO:0043303 19 0.110
epidermis morphogenesis GO:0048730 33 0.110
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.109
extracellular structure organization GO:0043062 148 0.109
Mouse
stem cell proliferation GO:0072089 117 0.109
hair follicle morphogenesis GO:0031069 29 0.108
nephron tubule development GO:0072080 84 0.108
cellular divalent inorganic cation homeostasis GO:0072503 127 0.107
regulation of protein kinase activity GO:0045859 232 0.107
determination of left right symmetry GO:0007368 80 0.106
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 11 0.106
axon ensheathment GO:0008366 76 0.106
ribonucleoside catabolic process GO:0042454 206 0.106
branching involved in ureteric bud morphogenesis GO:0001658 56 0.106
regulation of neuron differentiation GO:0045664 281 0.106
developmental maturation GO:0021700 193 0.105
Fly
leukocyte homeostasis GO:0001776 79 0.105
g protein coupled receptor signaling pathway GO:0007186 243 0.105
Mouse Fly
respiratory tube development GO:0030323 167 0.105
ensheathment of neurons GO:0007272 76 0.105
generation of precursor metabolites and energy GO:0006091 103 0.104
pattern specification involved in kidney development GO:0061004 8 0.104
positive regulation of lymphocyte differentiation GO:0045621 61 0.104
neuron projection extension GO:1990138 64 0.104
response to molecule of bacterial origin GO:0002237 143 0.104
regulation of hexokinase activity GO:1903299 5 0.104
monocarboxylic acid metabolic process GO:0032787 191 0.103
dichotomous subdivision of an epithelial terminal unit GO:0060600 11 0.103
placenta development GO:0001890 140 0.103
dorsal ventral neural tube patterning GO:0021904 28 0.103
kidney vasculature development GO:0061440 15 0.103
cellular response to gonadotropin stimulus GO:0071371 4 0.102
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.102
embryonic eye morphogenesis GO:0048048 29 0.102
mesangial cell development GO:0072143 4 0.102
renal system development GO:0072001 225 0.102
negative regulation of phosphate metabolic process GO:0045936 184 0.102
synaptic transmission GO:0007268 329 0.101
Mouse Fly
inner ear receptor stereocilium organization GO:0060122 23 0.101
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.101
response to organic cyclic compound GO:0014070 198 0.101
response to drug GO:0042493 75 0.101
negative regulation of carbohydrate metabolic process GO:0045912 19 0.100
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.100
forebrain development GO:0030900 302 0.100
regulation of ion transmembrane transporter activity GO:0032412 54 0.099
regulation of neuron apoptotic process GO:0043523 122 0.099
lung morphogenesis GO:0060425 50 0.099
epithelium migration GO:0090132 63 0.097
leukocyte degranulation GO:0043299 27 0.097
cardiac muscle cell proliferation GO:0060038 31 0.097
b cell activation GO:0042113 161 0.097
Mouse
cellular glucose homeostasis GO:0001678 52 0.096
response to oxidative stress GO:0006979 123 0.096
positive regulation of bmp signaling pathway GO:0030513 23 0.096
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.095
response to testosterone GO:0033574 3 0.095
blastocyst development GO:0001824 80 0.095
positive regulation of thymocyte migration GO:2000412 2 0.095
regulation of nucleocytoplasmic transport GO:0046822 73 0.095
mast cell activation involved in immune response GO:0002279 20 0.094
ectoderm formation GO:0001705 3 0.094
negative regulation of secretion GO:0051048 61 0.093
pronephric nephron development GO:0039019 1 0.093
intrinsic apoptotic signaling pathway GO:0097193 132 0.092
amide transport GO:0042886 138 0.091
purine ribonucleotide metabolic process GO:0009150 290 0.091
Mouse
mesoderm formation GO:0001707 62 0.091
negative regulation of homeostatic process GO:0032845 71 0.091
Mouse
regulation of proteolysis GO:0030162 164 0.090

Lgr4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.620
disease of anatomical entity DOID:7 0 0.620
eye and adnexa disease DOID:1492 0 0.620
nervous system disease DOID:863 0 0.620
eye disease DOID:5614 0 0.221