Mus musculus

177 known processes

Lmna

lamin A

(Aliases: Dhe)

Lmna biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane organization GO:0061024 245 0.956
organelle assembly GO:0070925 177 0.950
Worm
positive regulation of cellular amine metabolic process GO:0033240 5 0.924
actin cytoskeleton organization GO:0030036 220 0.917
Worm Fly
protein localization to membrane GO:0072657 108 0.912
myofibril assembly GO:0030239 34 0.887
Worm
response to growth factor GO:0070848 198 0.882
cation transport GO:0006812 399 0.877
cellular component assembly involved in morphogenesis GO:0010927 139 0.876
Worm
sensory organ morphogenesis GO:0090596 242 0.852
Fly
regulation of organelle organization GO:0033043 289 0.843
actin filament organization GO:0007015 113 0.833
Fly
muscle contraction GO:0006936 101 0.793
actomyosin structure organization GO:0031032 56 0.783
Worm
muscle tissue development GO:0060537 308 0.773
endomembrane system organization GO:0010256 147 0.755
amine metabolic process GO:0009308 45 0.753
release of cytochrome c from mitochondria GO:0001836 23 0.751
axonogenesis GO:0007409 274 0.734
cell adhesion GO:0007155 329 0.712
striated muscle tissue development GO:0014706 293 0.710
extrinsic apoptotic signaling pathway GO:0097191 126 0.706
ras protein signal transduction GO:0007265 77 0.688
endocytosis GO:0006897 168 0.687
Worm
organonitrogen compound catabolic process GO:1901565 264 0.682
protein targeting GO:0006605 143 0.648
positive regulation of growth GO:0045927 104 0.640
Worm
regulation of wound healing GO:0061041 40 0.636
digestive tract development GO:0048565 190 0.624
Fly
ribonucleotide metabolic process GO:0009259 291 0.621
negative regulation of cellular component organization GO:0051129 194 0.619
negative regulation of apoptotic signaling pathway GO:2001234 104 0.606
regulation of cell motility GO:2000145 236 0.600
positive regulation of mapk cascade GO:0043410 170 0.597
regulation of apoptotic signaling pathway GO:2001233 197 0.583
negative regulation of cell proliferation GO:0008285 296 0.556
axon guidance GO:0007411 141 0.555
nucleoside catabolic process GO:0009164 206 0.543
metal ion homeostasis GO:0055065 189 0.532
nucleus localization GO:0051647 20 0.523
Fly
ribonucleoside catabolic process GO:0042454 206 0.513
positive regulation of vasoconstriction GO:0045907 4 0.506
oocyte axis specification GO:0007309 2 0.503
regulation of hydrolase activity GO:0051336 246 0.501
striated muscle cell development GO:0055002 125 0.498
protein kinase b signaling GO:0043491 74 0.493
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.487
negative regulation of epithelial cell proliferation GO:0050680 64 0.486
regulation of fat cell differentiation GO:0045598 81 0.485
purine nucleoside metabolic process GO:0042278 241 0.480
sarcomere organization GO:0045214 24 0.474
establishment of protein localization to membrane GO:0090150 54 0.473
cellular ketone metabolic process GO:0042180 84 0.463
muscle cell differentiation GO:0042692 261 0.461
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.459
response to epidermal growth factor GO:0070849 4 0.456
wound healing GO:0042060 157 0.451
myeloid cell differentiation GO:0030099 233 0.451
synaptic transmission GO:0007268 329 0.450
dna metabolic process GO:0006259 303 0.450
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.449
cytoplasmic transport GO:0016482 234 0.447
mitochondrion organization GO:0007005 134 0.446
cellular response to growth factor stimulus GO:0071363 197 0.446
extracellular structure organization GO:0043062 148 0.440
regulation of cellular component biogenesis GO:0044087 181 0.431
Fly
p38mapk cascade GO:0038066 4 0.431
response to oxygen levels GO:0070482 62 0.423
Human
skeletal system development GO:0001501 356 0.423
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.415
protein localization to plasma membrane GO:0072659 57 0.411
apoptotic signaling pathway GO:0097190 306 0.409
ribonucleoside triphosphate catabolic process GO:0009203 199 0.408
neuronal action potential GO:0019228 54 0.407
nucleoside monophosphate metabolic process GO:0009123 85 0.406
calcium ion transport GO:0006816 159 0.402
regulation of cellular amine metabolic process GO:0033238 20 0.400
digestive system development GO:0055123 200 0.400
Fly
regulation of vesicle mediated transport GO:0060627 139 0.398
nucleobase containing small molecule metabolic process GO:0055086 352 0.395
muscle system process GO:0003012 141 0.391
cellular response to amino acid stimulus GO:0071230 29 0.386
transmembrane transport GO:0055085 412 0.385
regulation of endocytosis GO:0030100 69 0.382
regulation of body fluid levels GO:0050878 162 0.381
glycosyl compound metabolic process GO:1901657 246 0.379
regulation of ion transport GO:0043269 215 0.377
intracellular protein transport GO:0006886 204 0.376
response to hyperoxia GO:0055093 2 0.369
platelet aggregation GO:0070527 20 0.363
divalent metal ion transport GO:0070838 172 0.360
fatty acid metabolic process GO:0006631 121 0.349
microtubule polymerization or depolymerization GO:0031109 26 0.339
ion transmembrane transport GO:0034220 361 0.339
regulation of cellular response to growth factor stimulus GO:0090287 82 0.339
actin filament based movement GO:0030048 23 0.338
cell substrate adhesion GO:0031589 130 0.337
purine nucleoside catabolic process GO:0006152 205 0.336
organelle localization GO:0051640 179 0.334
Fly
regulation of cellular ketone metabolic process GO:0010565 66 0.331
cardiac muscle tissue development GO:0048738 130 0.330
muscle cell development GO:0055001 133 0.328
oxidation reduction process GO:0055114 342 0.326
positive regulation of intracellular transport GO:0032388 70 0.325
gliogenesis GO:0042063 141 0.323
positive regulation of cell growth GO:0030307 33 0.322
epithelium migration GO:0090132 63 0.321
ribose phosphate metabolic process GO:0019693 291 0.320
hemostasis GO:0007599 78 0.319
response to amino acid GO:0043200 37 0.317
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.315
regulation of mapk cascade GO:0043408 248 0.314
regulation of peptidase activity GO:0052547 96 0.312
detection of external stimulus GO:0009581 61 0.310
atp metabolic process GO:0046034 75 0.309
ribonucleotide catabolic process GO:0009261 208 0.305
divalent inorganic cation transport GO:0072511 178 0.305
protein localization to nucleus GO:0034504 121 0.302
nucleoside phosphate metabolic process GO:0006753 338 0.298
cellular calcium ion homeostasis GO:0006874 119 0.298
plasma membrane organization GO:0007009 90 0.297
regulation of ras protein signal transduction GO:0046578 114 0.297
regulation of system process GO:0044057 200 0.295
cellular amine metabolic process GO:0044106 44 0.293
regulation of anatomical structure size GO:0090066 178 0.292
Fly
cytosolic calcium ion transport GO:0060401 48 0.291
cation homeostasis GO:0055080 212 0.289
negative regulation of anoikis GO:2000811 2 0.287
oocyte differentiation GO:0009994 35 0.287
positive regulation of apoptotic process GO:0043065 217 0.284
embryonic placenta development GO:0001892 98 0.282
regulation of actin filament based process GO:0032970 99 0.279
Fly
regulation of erk1 and erk2 cascade GO:0070372 71 0.278
skeletal muscle organ development GO:0060538 163 0.277
meiotic cell cycle GO:0051321 122 0.275
Worm
negative regulation of cell cycle GO:0045786 123 0.272
Worm
regulation of muscle system process GO:0090257 80 0.271
nucleocytoplasmic transport GO:0006913 139 0.270
reactive oxygen species biosynthetic process GO:1903409 8 0.267
skin development GO:0043588 220 0.266
ameboidal type cell migration GO:0001667 128 0.266
positive regulation of ras protein signal transduction GO:0046579 13 0.265
purine nucleotide metabolic process GO:0006163 302 0.263
response to uv a GO:0070141 1 0.258
regulation of defense response GO:0031347 233 0.258
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.258
purine nucleoside triphosphate catabolic process GO:0009146 203 0.257
purine ribonucleoside catabolic process GO:0046130 205 0.256
circulatory system process GO:0003013 197 0.254
Zebrafish
vasoconstriction GO:0042310 27 0.253
cellular lipid metabolic process GO:0044255 323 0.253
signal transduction in absence of ligand GO:0038034 55 0.250
heterocycle catabolic process GO:0046700 280 0.248
purine nucleoside triphosphate metabolic process GO:0009144 226 0.245
synapse organization GO:0050808 125 0.245
cellular amino acid metabolic process GO:0006520 103 0.244
myosin filament organization GO:0031033 3 0.238
Worm
developmental maturation GO:0021700 193 0.238
smooth muscle contraction GO:0006939 44 0.236
establishment or maintenance of cell polarity GO:0007163 86 0.234
ossification GO:0001503 216 0.233
nucleotide catabolic process GO:0009166 217 0.232
ribonucleoside monophosphate catabolic process GO:0009158 57 0.231
regulation of cellular component size GO:0032535 121 0.231
Fly
cellular protein complex assembly GO:0043623 116 0.228
Worm Fly
fatty acid transmembrane transport GO:1902001 1 0.227
positive regulation of neuron projection development GO:0010976 79 0.226
positive regulation of protein kinase b signaling GO:0051897 32 0.226
monocarboxylic acid metabolic process GO:0032787 191 0.225
regulation of transferase activity GO:0051338 263 0.223
macromolecule catabolic process GO:0009057 281 0.223
Worm
positive regulation of glial cell proliferation GO:0060252 4 0.222
regulation of protein targeting GO:1903533 61 0.219
purine containing compound metabolic process GO:0072521 311 0.216
regionalization GO:0003002 337 0.215
connective tissue development GO:0061448 179 0.214
Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.213
purine ribonucleotide catabolic process GO:0009154 208 0.211
negative regulation of cellular amine metabolic process GO:0033239 1 0.211
substrate dependent cell migration cell extension GO:0006930 4 0.210
blood coagulation GO:0007596 76 0.208
negative regulation of intracellular signal transduction GO:1902532 167 0.208
cellular response to inorganic substance GO:0071241 37 0.206
atp catabolic process GO:0006200 55 0.206
negative regulation of molecular function GO:0044092 258 0.204
positive regulation of endocytosis GO:0045807 42 0.204
formation of radial glial scaffolds GO:0021943 4 0.196
cell maturation GO:0048469 127 0.194
organic cyclic compound catabolic process GO:1901361 295 0.194
regulation of receptor activity GO:0010469 41 0.193
epithelial cell migration GO:0010631 63 0.192
regulation of cellular catabolic process GO:0031329 242 0.191
microtubule based process GO:0007017 236 0.191
protein processing GO:0016485 163 0.190
negative regulation of immature t cell proliferation GO:0033087 3 0.188
nucleoside triphosphate metabolic process GO:0009141 230 0.188
positive regulation of protein targeting to membrane GO:0090314 7 0.182
nucleotide metabolic process GO:0009117 332 0.181
cell growth GO:0016049 130 0.180
oocyte construction GO:0007308 2 0.179
atrial ventricular junction remodeling GO:0003294 2 0.179
regulation of neuron differentiation GO:0045664 281 0.179
blood vessel morphogenesis GO:0048514 285 0.175
positive regulation of homeostatic process GO:0032846 64 0.173
regulation of cell growth GO:0001558 91 0.172
purine nucleotide catabolic process GO:0006195 211 0.172
establishment of protein localization to organelle GO:0072594 118 0.170
protein catabolic process GO:0030163 221 0.169
Worm
cellular metal ion homeostasis GO:0006875 151 0.168
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.168
epithelial cell development GO:0002064 159 0.166
negative regulation of hydrolase activity GO:0051346 71 0.166
kidney development GO:0001822 213 0.166
peptidyl amino acid modification GO:0018193 336 0.163
cytokine mediated signaling pathway GO:0019221 115 0.160
regulation of cell shape GO:0008360 39 0.159
regulation of fatty acid metabolic process GO:0019217 28 0.158
hair follicle development GO:0001942 85 0.158
positive regulation of map kinase activity GO:0043406 84 0.156
glycosyl compound catabolic process GO:1901658 206 0.156
striated muscle myosin thick filament assembly GO:0071688 1 0.156
Worm
regulation of ventricular cardiac muscle cell membrane depolarization GO:0060373 2 0.156
dendrite development GO:0016358 115 0.155
determination of left right symmetry GO:0007368 80 0.155
regulation of mitotic cell cycle GO:0007346 126 0.154
Worm
aromatic compound catabolic process GO:0019439 286 0.153
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.153
lactation GO:0007595 25 0.153
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.152
response to fibroblast growth factor GO:0071774 47 0.152
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.152
cardiac muscle cell differentiation GO:0055007 69 0.152
heart morphogenesis GO:0003007 178 0.150
defense response to bacterium GO:0042742 119 0.150
negative regulation of cell migration GO:0030336 59 0.150
purine ribonucleotide metabolic process GO:0009150 290 0.150
negative regulation of phosphate metabolic process GO:0045936 184 0.149
regulation of protein serine threonine kinase activity GO:0071900 157 0.149
coagulation GO:0050817 78 0.148
establishment of organelle localization GO:0051656 122 0.148
Fly
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.148
angiogenesis GO:0001525 201 0.148
negative regulation of release of cytochrome c from mitochondria GO:0090201 6 0.147
regulation of cell migration GO:0030334 219 0.146
regulation of transmembrane transport GO:0034762 128 0.145
cellular response to insulin stimulus GO:0032869 78 0.145
ribonucleoside triphosphate metabolic process GO:0009199 220 0.144
glial cell differentiation GO:0010001 131 0.144
multi multicellular organism process GO:0044706 109 0.144
Worm
axon regeneration GO:0031103 12 0.144
ensheathment of neurons GO:0007272 76 0.143
positive regulation of neuron differentiation GO:0045666 141 0.143
regulation of establishment of protein localization GO:0070201 181 0.141
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.140
organophosphate catabolic process GO:0046434 232 0.140
regulation of protein localization GO:0032880 231 0.140
cellular response to abiotic stimulus GO:0071214 56 0.140
blood vessel endothelial cell migration GO:0043534 23 0.139
response to organonitrogen compound GO:0010243 246 0.139
epidermis development GO:0008544 187 0.139
cellular nitrogen compound catabolic process GO:0044270 280 0.138
branching morphogenesis of an epithelial tube GO:0048754 159 0.138
Fly
protein maturation GO:0051604 176 0.137
anatomical structure homeostasis GO:0060249 145 0.137
tissue migration GO:0090130 68 0.136
neuron apoptotic process GO:0051402 142 0.135
positive regulation of dna replication GO:0045740 9 0.135
notochord cell differentiation GO:0060034 1 0.134
cellular response to epidermal growth factor stimulus GO:0071364 4 0.133
metanephric glomerular mesangium development GO:0072223 3 0.131
muscle adaptation GO:0043500 39 0.131
positive regulation of protein kinase activity GO:0045860 144 0.131
milk ejection GO:0060156 1 0.131
positive regulation of axon extension GO:0045773 20 0.131
regulation of metal ion transport GO:0010959 106 0.130
monocyte differentiation GO:0030224 9 0.129
negative regulation of microtubule depolymerization GO:0007026 13 0.129
central nervous system morphogenesis GO:0021551 2 0.129
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.129
single organismal cell cell adhesion GO:0016337 131 0.129
regulation of nucleotide metabolic process GO:0006140 169 0.128
canonical wnt signaling pathway GO:0060070 130 0.128
negative regulation of cell motility GO:2000146 61 0.128
calcium ion transport into cytosol GO:0060402 48 0.127
purine ribonucleoside metabolic process GO:0046128 241 0.127
regulation of ion homeostasis GO:2000021 64 0.125
negative regulation of protein depolymerization GO:1901880 21 0.124
negative regulation of protein metabolic process GO:0051248 282 0.123
carbohydrate derivative catabolic process GO:1901136 231 0.123
multicellular organismal catabolic process GO:0044243 7 0.123
positive regulation of cell migration GO:0030335 109 0.122
divalent inorganic cation homeostasis GO:0072507 138 0.122
tissue remodeling GO:0048771 102 0.122
female gamete generation GO:0007292 74 0.121
positive regulation of intracellular protein transport GO:0090316 42 0.121
protein import into nucleus GO:0006606 95 0.121
small gtpase mediated signal transduction GO:0007264 97 0.121
neuron projection guidance GO:0097485 141 0.121
ribonucleoside metabolic process GO:0009119 245 0.119
response to increased oxygen levels GO:0036296 2 0.119
plasma membrane long chain fatty acid transport GO:0015911 1 0.118
regulation of microtubule depolymerization GO:0031114 13 0.118
protein modification by small protein conjugation GO:0032446 187 0.118
cellular ion homeostasis GO:0006873 165 0.118
forebrain development GO:0030900 302 0.117
biomineral tissue development GO:0031214 64 0.116
cellular divalent inorganic cation homeostasis GO:0072503 127 0.116
cardiocyte differentiation GO:0035051 87 0.116
positive regulation of organelle organization GO:0010638 128 0.116
regulation of fibroblast proliferation GO:0048145 34 0.116
cardiac myofibril assembly GO:0055003 12 0.115
cellular response to external stimulus GO:0071496 88 0.115
multicellular organismal homeostasis GO:0048871 164 0.115
negative regulation of endopeptidase activity GO:0010951 44 0.114
positive regulation of cell motility GO:2000147 116 0.112
gastrulation GO:0007369 116 0.112
response to interleukin 1 GO:0070555 11 0.111
microtubule cytoskeleton organization GO:0000226 157 0.111
negative regulation of cellular protein metabolic process GO:0032269 247 0.110
respiratory system development GO:0060541 190 0.110
Fly
embryonic organ morphogenesis GO:0048562 276 0.109
protein autophosphorylation GO:0046777 61 0.109
positive regulation of programmed cell death GO:0043068 218 0.108
rho protein signal transduction GO:0007266 32 0.108
negative regulation of synapse assembly GO:0051964 3 0.108
glucose homeostasis GO:0042593 128 0.108
regulation of cell cycle GO:0051726 281 0.107
Worm
cellular chemical homeostasis GO:0055082 215 0.107
regulation of calcium ion transport into cytosol GO:0010522 31 0.106
appendage morphogenesis GO:0035107 149 0.106
regulation of blood pressure GO:0008217 93 0.105
erk1 and erk2 cascade GO:0070371 77 0.105
ear development GO:0043583 200 0.104
microtubule depolymerization GO:0007019 15 0.104
cellular response to hormone stimulus GO:0032870 150 0.104
regulation of osteoblast differentiation GO:0045667 67 0.104
cell differentiation involved in kidney development GO:0061005 33 0.103
cellular macromolecule catabolic process GO:0044265 206 0.103
multi organism behavior GO:0051705 62 0.102
Worm
lymphocyte differentiation GO:0030098 242 0.102
positive regulation of fibroblast proliferation GO:0048146 20 0.102
regulation of lymphocyte proliferation GO:0050670 117 0.101
negative regulation of phagocytosis GO:0050765 4 0.101
membrane raft assembly GO:0001765 3 0.101
innate immune response GO:0045087 157 0.101
positive regulation of apoptotic signaling pathway GO:2001235 95 0.101
urogenital system development GO:0001655 261 0.100
focal adhesion assembly GO:0048041 19 0.100
positive regulation of cell projection organization GO:0031346 95 0.100
regulation of cell projection organization GO:0031344 206 0.100
positive regulation of vasodilation GO:0045909 3 0.099
establishment of protein localization to plasma membrane GO:0090002 34 0.099
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.098
filopodium assembly GO:0046847 19 0.098
purine nucleoside monophosphate catabolic process GO:0009128 58 0.098
ventricular cardiac muscle cell action potential GO:0086005 4 0.098
development of primary sexual characteristics GO:0045137 143 0.097
Worm Fly
positive regulation of cell development GO:0010720 237 0.097
reactive nitrogen species metabolic process GO:2001057 0 0.097
lens development in camera type eye GO:0002088 62 0.097
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.096
camera type eye development GO:0043010 266 0.096
regulation of ossification GO:0030278 112 0.096
positive regulation of cytoplasmic transport GO:1903651 40 0.096
cholesterol storage GO:0010878 4 0.094
single organism nuclear import GO:1902593 95 0.094
calcium ion homeostasis GO:0055074 127 0.094
olfactory learning GO:0008355 2 0.094
negative regulation of bmp signaling pathway GO:0030514 35 0.094
platelet morphogenesis GO:0036344 13 0.093
defense response to gram positive bacterium GO:0050830 50 0.093
regulation of mitochondrion organization GO:0010821 27 0.093
multi organism reproductive behavior GO:0044705 29 0.092
Worm
regulation of histone modification GO:0031056 56 0.092
negative regulation of organelle organization GO:0010639 90 0.092
sensory perception GO:0007600 245 0.092
positive regulation of protein transport GO:0051222 93 0.091
protein depolymerization GO:0051261 34 0.090
neuropilin signaling pathway GO:0038189 2 0.090
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.090
eye photoreceptor cell differentiation GO:0001754 41 0.090
regulation of cytoplasmic transport GO:1903649 112 0.089
cellular response to acid chemical GO:0071229 68 0.089
limb development GO:0060173 166 0.089
salivary gland morphogenesis GO:0007435 33 0.088
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.088
peptidyl tyrosine modification GO:0018212 145 0.088
reactive oxygen species metabolic process GO:0072593 84 0.088
engulfment of apoptotic cell GO:0043652 3 0.088
response to metal ion GO:0010038 47 0.088
microglia development GO:0014005 2 0.088
positive regulation of protein modification process GO:0031401 299 0.087
regulation of phagocytosis GO:0050764 33 0.087
face morphogenesis GO:0060325 29 0.087
defense response to other organism GO:0098542 197 0.087
fibroblast proliferation GO:0048144 35 0.087
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.087
protein ubiquitination GO:0016567 171 0.086
myosin filament assembly GO:0031034 2 0.086
Worm
regulation of cell projection assembly GO:0060491 38 0.085
cardiac muscle cell development GO:0055013 39 0.085
positive regulation of nitric oxide synthase activity GO:0051000 2 0.084
bone development GO:0060348 120 0.084
regulation of cell adhesion GO:0030155 154 0.084
placenta development GO:0001890 140 0.084
positive regulation of ion transport GO:0043270 65 0.083
regulation of ion transmembrane transport GO:0034765 119 0.083
ribonucleoside monophosphate metabolic process GO:0009161 80 0.083
regulation of endothelial cell proliferation GO:0001936 23 0.082
cell matrix adhesion GO:0007160 68 0.082
ovarian follicle development GO:0001541 40 0.082
response to alcohol GO:0097305 48 0.081
cardiac cell development GO:0055006 41 0.081
chemotaxis GO:0006935 247 0.079
cardiac chamber development GO:0003205 108 0.078
organelle fission GO:0048285 170 0.078
Worm
regulation of secretion GO:0051046 274 0.078
gonad development GO:0008406 141 0.078
Worm Fly
foramen ovale closure GO:0035922 1 0.077
actin polymerization or depolymerization GO:0008154 54 0.076
Fly
lipid homeostasis GO:0055088 63 0.076
positive regulation of protein export from nucleus GO:0046827 4 0.076
protein modification by small protein conjugation or removal GO:0070647 207 0.075
digestive tract morphogenesis GO:0048546 147 0.075
Fly
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.075
cell recognition GO:0008037 83 0.075
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.075
developmental growth involved in morphogenesis GO:0060560 138 0.074
regulation of intracellular protein transport GO:0033157 82 0.073
mitotic nuclear division GO:0007067 48 0.073
Worm
organonitrogen compound biosynthetic process GO:1901566 192 0.072
positive regulation of glomerular filtration GO:0003104 1 0.071
fat cell differentiation GO:0045444 160 0.071
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.070
organophosphate ester transport GO:0015748 28 0.070
positive regulation of endothelial cell migration GO:0010595 12 0.070
cellular response to organonitrogen compound GO:0071417 145 0.070
regulation of chromatin modification GO:1903308 57 0.070
collagen catabolic process GO:0030574 6 0.070
positive regulation of osteoblast differentiation GO:0045669 34 0.069
cardiac muscle tissue morphogenesis GO:0055008 44 0.069
proteoglycan metabolic process GO:0006029 38 0.069
dna replication GO:0006260 52 0.068
response to decreased oxygen levels GO:0036293 59 0.068
Human
membrane fusion GO:0061025 38 0.068
positive regulation of chromosome organization GO:2001252 33 0.068
developmental cell growth GO:0048588 84 0.068
vesicle localization GO:0051648 86 0.068
positive regulation of fat cell differentiation GO:0045600 32 0.068
apoptotic mitochondrial changes GO:0008637 48 0.068
regulation of cytoskeleton organization GO:0051493 122 0.068
Fly
regulation of osteoblast proliferation GO:0033688 15 0.067
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.067
response to calcium ion GO:0051592 20 0.067
regulation of actin filament length GO:0030832 45 0.067
Fly
cell chemotaxis GO:0060326 81 0.067
sodium ion transport GO:0006814 73 0.067
actin cytoskeleton reorganization GO:0031532 21 0.066
negative regulation of growth GO:0045926 99 0.066
chromatin organization GO:0006325 206 0.066
Fly
nerve development GO:0021675 67 0.066
regulation of protein kinase b signaling GO:0051896 56 0.066
nucleoside phosphate catabolic process GO:1901292 222 0.066
keratinocyte migration GO:0051546 3 0.066
positive regulation of nervous system development GO:0051962 221 0.066
interleukin 5 secretion GO:0072603 2 0.066
positive regulation of cell death GO:0010942 224 0.066
rna 3 end processing GO:0031123 20 0.066
regulation of hemostasis GO:1900046 28 0.065
single organism cell adhesion GO:0098602 156 0.065
regulation of intracellular transport GO:0032386 159 0.065
appendage development GO:0048736 166 0.065
head morphogenesis GO:0060323 34 0.065
retina development in camera type eye GO:0060041 119 0.064
regulation of blood coagulation GO:0030193 28 0.064
positive regulation of glucose transport GO:0010828 16 0.064
cell junction assembly GO:0034329 52 0.064
skeletal system morphogenesis GO:0048705 203 0.064

Lmna disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.854
Human
disease of anatomical entity DOID:7 0 0.854
Human
musculoskeletal system disease DOID:17 0 0.854
Human
muscle tissue disease DOID:66 0 0.854
Human
connective tissue disease DOID:65 0 0.824
myopathy DOID:423 0 0.690
Human
bone development disease DOID:0080006 0 0.365
bone disease DOID:0080001 0 0.365
muscular dystrophy DOID:9884 0 0.253
Human
heart disease DOID:114 0 0.142
Human
cardiovascular system disease DOID:1287 0 0.142
Human
cardiomyopathy DOID:0050700 0 0.127
Human
cancer DOID:162 0 0.101
disease of cellular proliferation DOID:14566 0 0.101
organ system cancer DOID:0050686 0 0.101
sensory system disease DOID:0050155 0 0.082
nervous system disease DOID:863 0 0.082
Human