Mus musculus

125 known processes

Lmx1b

LIM homeobox transcription factor 1 beta

(Aliases: MGC159172,LMX1.1,LMX1.2)

Lmx1b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.999
dopaminergic neuron differentiation GO:0071542 14 0.997
gastrulation GO:0007369 116 0.995
Mouse
paraxial mesodermal cell differentiation GO:0048342 2 0.995
pituitary gland development GO:0021983 38 0.994
Mouse
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.993
axon guidance GO:0007411 141 0.991
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.991
appendage morphogenesis GO:0035107 149 0.991
pyramidal neuron migration GO:0021852 1 0.990
formation of primary germ layer GO:0001704 77 0.989
Mouse
embryonic organ morphogenesis GO:0048562 276 0.989
Zebrafish Mouse
ectoderm formation GO:0001705 3 0.988
Mouse
digestive tract development GO:0048565 190 0.987
Mouse
mesoderm development GO:0007498 100 0.986
Mouse
regionalization GO:0003002 337 0.986
telencephalon development GO:0021537 186 0.986
Mouse
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.985
auditory receptor cell fate determination GO:0042668 3 0.985
substrate independent telencephalic tangential migration GO:0021826 8 0.985
Mouse
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.985
Mouse
forebrain development GO:0030900 302 0.984
Mouse
bmp signaling pathway GO:0030509 93 0.983
metencephalon development GO:0022037 89 0.980
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.978
forebrain cell migration GO:0021885 58 0.978
Mouse
regulation of bmp signaling pathway GO:0030510 60 0.977
metanephric nephron morphogenesis GO:0072273 19 0.977
Mouse
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.975
ear morphogenesis GO:0042471 118 0.975
Zebrafish
digestive tract morphogenesis GO:0048546 147 0.972
Mouse
neuron projection guidance GO:0097485 141 0.971
Mouse
motor neuron migration GO:0097475 4 0.971
Mouse
cerebral cortex neuron differentiation GO:0021895 19 0.971
Mouse
somitogenesis GO:0001756 69 0.970
Mouse
mesenchyme development GO:0060485 152 0.969
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.965
neuron migration GO:0001764 122 0.965
hindbrain development GO:0030902 128 0.964
inner ear morphogenesis GO:0042472 101 0.964
Zebrafish
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.962
nephron tubule morphogenesis GO:0072078 68 0.961
Mouse
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.958
nephron epithelium morphogenesis GO:0072088 68 0.957
Mouse
positive regulation of bmp signaling pathway GO:0030513 23 0.956
neural tube development GO:0021915 160 0.955
Zebrafish Mouse
cerebellum development GO:0021549 77 0.955
cell differentiation in hindbrain GO:0021533 24 0.955
Mouse
stem cell development GO:0048864 219 0.953
Mouse
hypophysis morphogenesis GO:0048850 3 0.950
somatotropin secreting cell differentiation GO:0060126 4 0.950
ureteric bud morphogenesis GO:0060675 62 0.946
Mouse
neuroblast differentiation GO:0014016 2 0.946
lung induction GO:0060492 3 0.945
rostrocaudal neural tube patterning GO:0021903 12 0.944
Zebrafish
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.941
Mouse
midbrain hindbrain boundary development GO:0030917 9 0.941
Zebrafish
limb morphogenesis GO:0035108 149 0.940
digestive system development GO:0055123 200 0.938
Mouse
cell proliferation in forebrain GO:0021846 30 0.938
Mouse
neuron fate specification GO:0048665 30 0.937
Mouse
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.931
pancreatic pp cell fate commitment GO:0003329 2 0.928
gastrulation with mouth forming second GO:0001702 29 0.927
Mouse
hindbrain formation GO:0021576 1 0.923
anterior commissure morphogenesis GO:0021960 6 0.923
spemann organizer formation GO:0060061 2 0.919
cell proliferation in hindbrain GO:0021534 10 0.918
cerebellar cortex development GO:0021695 48 0.918
Mouse
cardiocyte differentiation GO:0035051 87 0.918
Mouse
branching involved in ureteric bud morphogenesis GO:0001658 56 0.918
Mouse
cerebellar cortex formation GO:0021697 22 0.913
Mouse
epidermis development GO:0008544 187 0.913
Zebrafish Mouse
cerebellum formation GO:0021588 1 0.912
hindbrain morphogenesis GO:0021575 46 0.910
positive regulation of transcription by glucose GO:0046016 3 0.905
hippocampus development GO:0021766 52 0.903
Mouse
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.902
regulation of canonical wnt signaling pathway GO:0060828 82 0.902
Mouse
amine metabolic process GO:0009308 45 0.897
embryonic skeletal system development GO:0048706 120 0.893
Mouse
auditory receptor cell fate specification GO:0042667 1 0.892
hair follicle development GO:0001942 85 0.891
Mouse
telencephalon cell migration GO:0022029 55 0.890
Mouse
sensory organ morphogenesis GO:0090596 242 0.885
Zebrafish Mouse
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.879
mesonephric duct formation GO:0072181 2 0.879
pancreatic a cell fate commitment GO:0003326 2 0.878
spinal cord development GO:0021510 81 0.876
Mouse
midbrain hindbrain boundary maturation GO:0021732 1 0.872
ventral spinal cord interneuron differentiation GO:0021514 16 0.872
Mouse
metanephros morphogenesis GO:0003338 24 0.871
Mouse
heart formation GO:0060914 16 0.870
Mouse
gabaergic neuron differentiation GO:0097154 11 0.864
Mouse
cardiac ventricle morphogenesis GO:0003208 50 0.853
Mouse
central nervous system neuron development GO:0021954 67 0.853
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.851
axonogenesis GO:0007409 274 0.840
Mouse Worm
diencephalon morphogenesis GO:0048852 6 0.839
forebrain neuron development GO:0021884 30 0.834
Mouse
regulation of neuron projection development GO:0010975 169 0.832
cerebellar cortex morphogenesis GO:0021696 32 0.829
Mouse
morphogenesis of a polarized epithelium GO:0001738 37 0.828
embryonic appendage morphogenesis GO:0035113 126 0.826
renal system development GO:0072001 225 0.823
Zebrafish Mouse
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.822
neuromuscular process GO:0050905 99 0.817
cell fate specification GO:0001708 72 0.815
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.813
Zebrafish Mouse
regulation of cardioblast differentiation GO:0051890 3 0.811
metanephric tubule morphogenesis GO:0072173 9 0.809
lateral motor column neuron migration GO:0097477 3 0.809
Mouse
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.804
cerebral cortex radially oriented cell migration GO:0021799 31 0.803
Mouse
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.800
pancreatic pp cell differentiation GO:0003312 2 0.793
cardiac right atrium morphogenesis GO:0003213 3 0.792
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.790
mesoderm morphogenesis GO:0048332 64 0.783
oviduct development GO:0060066 3 0.782
Mouse
horizontal cell localization GO:0035852 1 0.781
Mouse
skin development GO:0043588 220 0.777
Zebrafish Mouse
cochlea morphogenesis GO:0090103 22 0.777
spermatogenesis GO:0007283 284 0.774
cerebral cortex gabaergic interneuron development GO:0021894 6 0.773
Mouse
spinal cord dorsal ventral patterning GO:0021513 23 0.773
Mouse
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.771
renal vesicle induction GO:0072034 3 0.770
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.769
diencephalon development GO:0021536 63 0.766
Mouse
axis elongation involved in somitogenesis GO:0090245 4 0.765
positive regulation of rhodopsin gene expression GO:0045872 2 0.761
neuron fate determination GO:0048664 9 0.759
appendage development GO:0048736 166 0.755
regulation of gastrulation GO:0010470 16 0.752
Mouse
globus pallidus development GO:0021759 2 0.751
nephron morphogenesis GO:0072028 69 0.751
Mouse
neural crest cell development GO:0014032 48 0.746
Mouse
regulation of heart morphogenesis GO:2000826 22 0.746
Mouse
regulation of vascular wound healing GO:0061043 2 0.745
artery development GO:0060840 53 0.742
neuron projection extension GO:1990138 64 0.742
Mouse
forebrain neuron differentiation GO:0021879 52 0.740
Mouse
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.738
ventral spinal cord interneuron fate commitment GO:0060579 14 0.737
Mouse
establishment of organ orientation GO:0048561 1 0.735
cardiac muscle tissue morphogenesis GO:0055008 44 0.723
Mouse
cardiac cell fate determination GO:0060913 2 0.721
Mouse
mesonephric tubule development GO:0072164 94 0.720
Mouse
renal capsule specification GO:0072130 1 0.718
urogenital system development GO:0001655 261 0.714
Zebrafish Mouse
hemangioblast cell differentiation GO:0060217 1 0.714
limb development GO:0060173 166 0.713
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.711
embryonic heart tube development GO:0035050 65 0.709
pallium development GO:0021543 120 0.709
Mouse
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.708
locomotory behavior GO:0007626 195 0.708
germ cell development GO:0007281 185 0.708
neural tube patterning GO:0021532 43 0.708
Zebrafish
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.706
ventral spinal cord interneuron specification GO:0021521 11 0.705
Mouse
skeletal system development GO:0001501 356 0.705
Mouse
stem cell differentiation GO:0048863 268 0.704
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.703
Mouse
inner medullary collecting duct development GO:0072061 2 0.701
cerebral cortex cell migration GO:0021795 44 0.700
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 42 0.699
Mouse
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.698
dorsal ventral axon guidance GO:0033563 3 0.696
positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 0.692
mesenchymal cell differentiation GO:0048762 107 0.692
Mouse
negative regulation of transcription by glucose GO:0045014 1 0.689
hair cycle GO:0042633 90 0.684
Mouse
limbic system development GO:0021761 72 0.683
Mouse
central nervous system vasculogenesis GO:0022009 3 0.682
central nervous system morphogenesis GO:0021551 2 0.678
metanephric dct cell differentiation GO:0072240 3 0.676
lung development GO:0030324 164 0.669
lung morphogenesis GO:0060425 50 0.667
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.666
Mouse
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.666
adenohypophysis development GO:0021984 14 0.666
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.665
mesonephric duct morphogenesis GO:0072180 4 0.664
ameboidal type cell migration GO:0001667 128 0.664
Mouse
trophectodermal cell differentiation GO:0001829 21 0.661
mesenchymal cell development GO:0014031 93 0.659
Mouse
inner ear receptor cell differentiation GO:0060113 61 0.658
Zebrafish
cellular component assembly involved in morphogenesis GO:0010927 139 0.651
monosaccharide metabolic process GO:0005996 106 0.648
ear development GO:0043583 200 0.647
Zebrafish
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.646
cell fate determination GO:0001709 32 0.641
Mouse
metanephric loop of henle development GO:0072236 4 0.641
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.640
forebrain anterior posterior pattern specification GO:0021797 5 0.638
respiratory system development GO:0060541 190 0.637
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.636
renal capsule formation GO:0072129 1 0.636
embryonic heart tube morphogenesis GO:0003143 51 0.635
neurohypophysis development GO:0021985 2 0.635
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.631
epithelial mesenchymal signaling involved in prostate gland development GO:0060738 2 0.629
regulation of embryonic development GO:0045995 71 0.626
Mouse
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.624
granulosa cell differentiation GO:0060014 1 0.623
spinal cord association neuron differentiation GO:0021527 14 0.623
Mouse
neuroblast fate determination GO:0007400 1 0.620
kidney morphogenesis GO:0060993 83 0.619
Mouse
brain morphogenesis GO:0048854 32 0.616
outflow tract morphogenesis GO:0003151 53 0.614
Mouse
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.614
hair cell differentiation GO:0035315 40 0.613
Zebrafish
astrocyte differentiation GO:0048708 43 0.613
carbohydrate homeostasis GO:0033500 128 0.610
regulation of cellular amine metabolic process GO:0033238 20 0.609
endocrine pancreas development GO:0031018 29 0.609
embryonic heart tube formation GO:0003144 1 0.605
mesoderm formation GO:0001707 62 0.601
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.595
Mouse
negative regulation of cell fate specification GO:0009996 4 0.595
carbon catabolite activation of transcription GO:0045991 4 0.594
regulation of secretion by cell GO:1903530 249 0.589
regulation of anagen GO:0051884 1 0.589
cerebral cortex development GO:0021987 86 0.588
Mouse
ureteric bud development GO:0001657 94 0.586
Mouse
ossification GO:0001503 216 0.584
neural tube closure GO:0001843 90 0.579
Mouse
hormone metabolic process GO:0042445 86 0.579
regulation of hormone secretion GO:0046883 88 0.579
interneuron migration from the subpallium to the cortex GO:0021830 7 0.575
Mouse
fourth ventricle development GO:0021592 2 0.574
Zebrafish
anatomical structure homeostasis GO:0060249 145 0.573
ventral midline development GO:0007418 4 0.572
regulation of organelle organization GO:0033043 289 0.571
muscle cell differentiation GO:0042692 261 0.569
Mouse
kidney development GO:0001822 213 0.569
Zebrafish Mouse
stem cell proliferation GO:0072089 117 0.567
endodermal cell fate specification GO:0001714 4 0.566
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.563
organelle fission GO:0048285 170 0.559
developmental cell growth GO:0048588 84 0.554
Mouse
regulation of neuron differentiation GO:0045664 281 0.548
Mouse
carbon catabolite repression of transcription GO:0045013 1 0.546
positive regulation of anagen GO:0051885 1 0.546
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.546
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.545
central nervous system neuron differentiation GO:0021953 162 0.544
astrocyte fate commitment GO:0060018 4 0.541
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.540
Mouse
corticotropin hormone secreting cell differentiation GO:0060128 3 0.540
glial cell differentiation GO:0010001 131 0.532
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.532
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.527
spinal cord motor neuron cell fate specification GO:0021520 13 0.525
Mouse
regulation of rhodopsin gene expression GO:0007468 3 0.524
meiotic nuclear division GO:0007126 115 0.523
negative regulation of cell development GO:0010721 169 0.523
Mouse
camera type eye development GO:0043010 266 0.521
neural precursor cell proliferation GO:0061351 121 0.521
Mouse
regulation of cardiac cell fate specification GO:2000043 1 0.516
skeletal muscle organ development GO:0060538 163 0.515
renal capsule morphogenesis GO:0072128 1 0.515
organic hydroxy compound metabolic process GO:1901615 203 0.512
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.511
primary neural tube formation GO:0014020 95 0.510
Mouse
olfactory bulb development GO:0021772 30 0.509
Mouse
mesodermal cell differentiation GO:0048333 22 0.508
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.508
phenol containing compound metabolic process GO:0018958 60 0.505
nephric duct formation GO:0072179 4 0.503
developmental growth involved in morphogenesis GO:0060560 138 0.502
Mouse
cell fate commitment GO:0045165 210 0.502
Mouse
embryonic limb morphogenesis GO:0030326 126 0.498
positive regulation of nervous system development GO:0051962 221 0.496
Mouse
regulation of myeloid cell differentiation GO:0045637 96 0.493
regulation of smoothened signaling pathway GO:0008589 58 0.487
negative regulation of gastrulation GO:2000542 3 0.486
cellular amino acid metabolic process GO:0006520 103 0.481
Worm
retinal ganglion cell axon guidance GO:0031290 18 0.479
Mouse
paraxial mesoderm morphogenesis GO:0048340 10 0.478
metanephric capsule morphogenesis GO:0072265 1 0.477
brain segmentation GO:0035284 3 0.476
epithelial tube morphogenesis GO:0060562 303 0.475
Mouse
ventricular cardiac myofibril assembly GO:0055005 3 0.475
retina morphogenesis in camera type eye GO:0060042 45 0.471
Mouse
metanephric epithelium development GO:0072207 21 0.471
metanephric nephron tubule development GO:0072234 16 0.462
metanephric tubule development GO:0072170 18 0.462
central nervous system projection neuron axonogenesis GO:0021952 21 0.462
metanephric nephron tubule formation GO:0072289 4 0.460
renal outer medulla development GO:0072054 2 0.459
cell proliferation in external granule layer GO:0021924 10 0.459
ventricular septum morphogenesis GO:0060412 27 0.459
gland development GO:0048732 330 0.457
Mouse
organic hydroxy compound biosynthetic process GO:1901617 77 0.456
mesonephric tubule morphogenesis GO:0072171 63 0.455
Mouse
mesenchyme morphogenesis GO:0072132 32 0.454
Mouse
regulation of neuroblast proliferation GO:1902692 27 0.452
outer medullary collecting duct development GO:0072060 1 0.449
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation GO:0044343 1 0.448
metanephric capsule specification GO:0072267 1 0.446
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.446
heart field specification GO:0003128 6 0.445
epithelial tube branching involved in lung morphogenesis GO:0060441 28 0.442
tube formation GO:0035148 140 0.441
Mouse
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.440
blood circulation GO:0008015 195 0.434
renal inner medulla development GO:0072053 3 0.433
regulation of endodermal cell differentiation GO:1903224 2 0.433
labyrinthine layer development GO:0060711 49 0.432
neuroblast proliferation GO:0007405 49 0.430
regulation of cellular amino acid metabolic process GO:0006521 5 0.430
adult behavior GO:0030534 135 0.426
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.425
regulation of auditory receptor cell differentiation GO:0045607 4 0.423
olfactory bulb interneuron development GO:0021891 7 0.422
medial motor column neuron differentiation GO:0021526 2 0.420
Mouse
spinal cord motor neuron migration GO:0097476 4 0.420
Mouse
aortic valve morphogenesis GO:0003180 4 0.418
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.417
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.417
cardiac septum development GO:0003279 59 0.415
Mouse
negative regulation of mesodermal cell fate specification GO:0042662 3 0.414
tongue development GO:0043586 18 0.406
extracellular structure organization GO:0043062 148 0.405
carbohydrate metabolic process GO:0005975 230 0.404
male gamete generation GO:0048232 285 0.403
cerebellum morphogenesis GO:0021587 42 0.403
respiratory tube development GO:0030323 167 0.402
forelimb morphogenesis GO:0035136 40 0.402
lens morphogenesis in camera type eye GO:0002089 24 0.402
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.401
atrial cardiac muscle tissue development GO:0003228 5 0.400
lung field specification GO:0060424 3 0.398
closure of optic fissure GO:0061386 2 0.396
Zebrafish
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.394
hindlimb morphogenesis GO:0035137 42 0.394
canonical wnt signaling pathway GO:0060070 130 0.393
Mouse
regulation of asymmetric cell division GO:0009786 4 0.393
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.393
cardiac cell fate specification GO:0060912 2 0.393
nuclear division GO:0000280 158 0.388
embryonic eye morphogenesis GO:0048048 29 0.388
Zebrafish
myotube differentiation GO:0014902 105 0.388
carbon catabolite regulation of transcription GO:0045990 4 0.387
olfactory lobe development GO:0021988 32 0.386
Mouse
primary prostatic bud elongation GO:0060516 2 0.381
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.379
cardiac pacemaker cell fate commitment GO:0060927 1 0.379
maintenance of apical basal cell polarity GO:0035090 3 0.378
Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.377
chemotaxis GO:0006935 247 0.376
Mouse
tendon formation GO:0035992 4 0.375
epidermal cell fate specification GO:0009957 1 0.375
prostate gland stromal morphogenesis GO:0060741 2 0.375
endocrine system development GO:0035270 98 0.373
Mouse
purkinje myocyte differentiation GO:0003168 1 0.373
regulation of neural precursor cell proliferation GO:2000177 70 0.372
Mouse
dorsal ventral neural tube patterning GO:0021904 28 0.372
glomerular mesangial cell differentiation GO:0072008 3 0.371
cerebellar granule cell precursor proliferation GO:0021930 10 0.371
positive regulation of transcription via serum response element binding GO:0010735 1 0.370
forebrain morphogenesis GO:0048853 17 0.370
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.369
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.369
molting cycle GO:0042303 90 0.367
Mouse
syncytium formation by plasma membrane fusion GO:0000768 42 0.367
regulation of organ formation GO:0003156 34 0.366
Mouse
neural crest cell migration GO:0001755 32 0.366
Mouse
regulation of cardiac muscle tissue development GO:0055024 31 0.365
chromatin organization GO:0006325 206 0.364
cranial nerve development GO:0021545 41 0.363
Mouse
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.363
Mouse
skeletal system morphogenesis GO:0048705 203 0.361
Mouse
negative regulation of prostatic bud formation GO:0060686 4 0.361
gonad development GO:0008406 141 0.360
Mouse
sensory system development GO:0048880 3 0.358
Mouse
left lung development GO:0060459 4 0.357
regulation of membrane potential GO:0042391 192 0.356
mesodermal cell migration GO:0008078 4 0.356
mapk cascade GO:0000165 281 0.354
positive regulation of neuroblast proliferation GO:0002052 19 0.352
positive regulation of wnt signaling pathway GO:0030177 45 0.351
cardiac muscle cell differentiation GO:0055007 69 0.349
central nervous system neuron axonogenesis GO:0021955 28 0.348
forebrain neuron fate commitment GO:0021877 13 0.347
Mouse
organ growth GO:0035265 117 0.346
primitive streak formation GO:0090009 10 0.342
Mouse
cerebellar purkinje cell granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation GO:0021937 6 0.341
Mouse
chondrocyte differentiation GO:0002062 72 0.341
determination of heart left right asymmetry GO:0061371 48 0.339
cardiac chamber morphogenesis GO:0003206 93 0.337
Mouse
neural tube formation GO:0001841 108 0.337
Mouse
blastocyst formation GO:0001825 33 0.337
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.336
cell migration involved in mesendoderm migration GO:0090134 1 0.335
clara cell differentiation GO:0060486 4 0.333
cerebellar purkinje cell differentiation GO:0021702 13 0.331
Mouse
trachea cartilage morphogenesis GO:0060535 4 0.330
mesangial cell differentiation GO:0072007 4 0.330
eye photoreceptor cell fate commitment GO:0042706 2 0.329
positive regulation of stem cell proliferation GO:2000648 59 0.329
axial mesodermal cell fate commitment GO:0048322 1 0.328
glandular epithelial cell differentiation GO:0002067 38 0.328
regulation of glucose metabolic process GO:0010906 60 0.326
segmentation GO:0035282 93 0.326
Mouse
establishment of monopolar cell polarity GO:0061162 8 0.324
regulation of peptide secretion GO:0002791 77 0.318
tissue homeostasis GO:0001894 115 0.315
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.315
heart induction GO:0003129 2 0.315
amide transport GO:0042886 138 0.315
embryonic skeletal system morphogenesis GO:0048704 91 0.314
Mouse
positive regulation of nephron tubule epithelial cell differentiation GO:2000768 1 0.314
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.313
establishment or maintenance of polarity of embryonic epithelium GO:0016332 1 0.311
stem cell fate determination GO:0048867 2 0.311
type b pancreatic cell differentiation GO:0003309 13 0.309
regulation of neural retina development GO:0061074 3 0.308
epithelial cell fate commitment GO:0072148 13 0.304
atrial cardiac muscle cell differentiation GO:0055011 2 0.304
motor neuron axon guidance GO:0008045 26 0.304
Mouse
spermatid development GO:0007286 108 0.304
cerebellar purkinje cell layer development GO:0021680 26 0.303
Mouse
aminoglycan metabolic process GO:0006022 34 0.302
epithelial cell development GO:0002064 159 0.301
Zebrafish
retinal bipolar neuron differentiation GO:0060040 5 0.298
regulation of mesonephros development GO:0061217 24 0.293
Mouse
cell differentiation involved in embryonic placenta development GO:0060706 26 0.292
kidney epithelium development GO:0072073 121 0.291
Mouse
negative regulation of testosterone biosynthetic process GO:2000225 1 0.291
cardiac muscle cell proliferation GO:0060038 31 0.290
cerebral cortex radial glia guided migration GO:0021801 17 0.289
positive regulation of neuron differentiation GO:0045666 141 0.289
mitral valve morphogenesis GO:0003183 4 0.288
pattern specification involved in metanephros development GO:0072268 4 0.288
metanephric capsule formation GO:0072266 1 0.286
endodermal cell fate commitment GO:0001711 12 0.286
somatotropin secreting cell development GO:0060133 2 0.283
kidney vasculature development GO:0061440 15 0.283
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.283
central nervous system segmentation GO:0035283 3 0.282
angiogenesis GO:0001525 201 0.282
Mouse
regulation of blood vessel size GO:0050880 56 0.281
pancreas development GO:0031016 57 0.281
Mouse
myeloid cell differentiation GO:0030099 233 0.278
regulation of binding GO:0051098 111 0.278
Mouse
neuroblast fate commitment GO:0014017 1 0.277
multicellular organism growth GO:0035264 161 0.277
cardiac muscle tissue growth GO:0055017 37 0.277
sodium ion transport GO:0006814 73 0.277
pulmonary myocardium development GO:0003350 3 0.276
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.275
cardiac right ventricle formation GO:0003219 3 0.273
regulation of endodermal cell fate specification GO:0042663 2 0.271
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.270
g protein coupled receptor signaling pathway GO:0007186 243 0.270
embryonic placenta development GO:0001892 98 0.267
atrial cardiac muscle cell development GO:0055014 2 0.266
kidney rudiment formation GO:0072003 3 0.265
hypothalamus cell migration GO:0021855 5 0.265
spinal cord motor neuron differentiation GO:0021522 35 0.264
Mouse
subpallium development GO:0021544 20 0.261
loop of henle development GO:0072070 10 0.259
regulation of myeloid leukocyte differentiation GO:0002761 58 0.258
regulation of transporter activity GO:0032409 57 0.256
dendrite development GO:0016358 115 0.254
Fly
atrioventricular node cell fate commitment GO:0060929 1 0.254
response to fibroblast growth factor GO:0071774 47 0.254
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.253
regulation of neuron death GO:1901214 134 0.250
Mouse
regulation of cell activation GO:0050865 289 0.247
female sex differentiation GO:0046660 84 0.246
Mouse
regulation of glial cell differentiation GO:0045685 41 0.245
positive regulation of interleukin 8 secretion GO:2000484 1 0.245
regulation of gliogenesis GO:0014013 50 0.244
epithelial cell morphogenesis GO:0003382 41 0.243
retina development in camera type eye GO:0060041 119 0.242
Zebrafish Mouse
negative regulation of glucokinase activity GO:0033132 4 0.241
regulation of leukocyte differentiation GO:1902105 159 0.241
embryonic forelimb morphogenesis GO:0035115 32 0.241
transdifferentiation GO:0060290 1 0.239
auditory receptor cell differentiation GO:0042491 37 0.239
Zebrafish
cellular response to carbohydrate stimulus GO:0071322 50 0.238
endocardial cushion morphogenesis GO:0003203 18 0.238
Mouse
positive regulation of camp mediated signaling GO:0043950 3 0.238
positive regulation of smoothened signaling pathway GO:0045880 23 0.237
female somatic sex determination GO:0019101 1 0.236
smoothened signaling pathway GO:0007224 105 0.236
anterior head development GO:0097065 2 0.235
Mouse
positive regulation of cell cell adhesion mediated by cadherin GO:2000049 2 0.235
oligodendrocyte development GO:0014003 20 0.234

Lmx1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.535
disease of anatomical entity DOID:7 0 0.535
nervous system disease DOID:863 0 0.535
eye and adnexa disease DOID:1492 0 0.368
eye disease DOID:5614 0 0.348