Mus musculus

78 known processes

Lonp1

lon peptidase 1, mitochondrial

(Aliases: Prss15,1200017E13Rik,LON)

Lonp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
translation GO:0006412 93 0.220
cellular amino acid metabolic process GO:0006520 103 0.208
response to endoplasmic reticulum stress GO:0034976 53 0.137
heterocycle catabolic process GO:0046700 280 0.096
oxidation reduction process GO:0055114 342 0.091
ion transmembrane transport GO:0034220 361 0.084
monocarboxylic acid metabolic process GO:0032787 191 0.080
mitochondrion organization GO:0007005 134 0.077
regulation of cellular ketone metabolic process GO:0010565 66 0.074
transmembrane transport GO:0055085 412 0.074
aromatic compound catabolic process GO:0019439 286 0.072
cristae formation GO:0042407 3 0.068
trna aminoacylation GO:0043039 1 0.068
regulation of translation GO:0006417 71 0.062
cellular ketone metabolic process GO:0042180 84 0.060
posttranscriptional regulation of gene expression GO:0010608 155 0.059
regulation of cellular amine metabolic process GO:0033238 20 0.056
response to topologically incorrect protein GO:0035966 25 0.055
purine containing compound metabolic process GO:0072521 311 0.053
cellular lipid metabolic process GO:0044255 323 0.052
purine ribonucleoside metabolic process GO:0046128 241 0.051
spermatogenesis GO:0007283 284 0.050
intracellular protein transport GO:0006886 204 0.049
ribonucleoside triphosphate catabolic process GO:0009203 199 0.047
positive regulation of cellular amine metabolic process GO:0033240 5 0.047
nucleobase containing small molecule metabolic process GO:0055086 352 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
protein processing GO:0016485 163 0.043
translational elongation GO:0006414 12 0.042
regulation of secretion GO:0051046 274 0.041
response to oxidative stress GO:0006979 123 0.041
carboxylic acid catabolic process GO:0046395 51 0.040
epidermis development GO:0008544 187 0.040
purine nucleotide metabolic process GO:0006163 302 0.040
negative regulation of cellular protein metabolic process GO:0032269 247 0.039
purine ribonucleotide metabolic process GO:0009150 290 0.038
male gamete generation GO:0048232 285 0.038
carbohydrate metabolic process GO:0005975 230 0.037
negative regulation of molecular function GO:0044092 258 0.037
ribose phosphate metabolic process GO:0019693 291 0.036
carbohydrate derivative catabolic process GO:1901136 231 0.036
glycosyl compound metabolic process GO:1901657 246 0.035
cellular amino acid biosynthetic process GO:0008652 22 0.033
regulation of cell activation GO:0050865 289 0.033
er nucleus signaling pathway GO:0006984 27 0.033
cellular amine metabolic process GO:0044106 44 0.033
organic cyclic compound catabolic process GO:1901361 295 0.033
cellular response to topologically incorrect protein GO:0035967 25 0.033
regulation of leukocyte proliferation GO:0070663 121 0.032
purine nucleoside catabolic process GO:0006152 205 0.032
protein maturation GO:0051604 176 0.032
purine ribonucleoside catabolic process GO:0046130 205 0.032
skin development GO:0043588 220 0.032
positive regulation of fatty acid oxidation GO:0046321 4 0.032
carboxylic acid biosynthetic process GO:0046394 86 0.032
protein localization to organelle GO:0033365 185 0.031
purine nucleotide catabolic process GO:0006195 211 0.031
organophosphate catabolic process GO:0046434 232 0.031
macromolecule catabolic process GO:0009057 281 0.031
nucleoside metabolic process GO:0009116 246 0.030
positive regulation of cell activation GO:0050867 158 0.030
ribonucleoside metabolic process GO:0009119 245 0.030
trna aminoacylation for protein translation GO:0006418 1 0.030
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
small molecule catabolic process GO:0044282 71 0.029
protein targeting GO:0006605 143 0.029
membrane fusion GO:0061025 38 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
germ cell development GO:0007281 185 0.029
purine containing compound catabolic process GO:0072523 213 0.029
establishment of protein localization to organelle GO:0072594 118 0.028
anion transport GO:0006820 177 0.028
positive regulation of lymphocyte activation GO:0051251 140 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.028
response to peptide hormone GO:0043434 127 0.028
alpha amino acid biosynthetic process GO:1901607 15 0.028
monosaccharide metabolic process GO:0005996 106 0.028
metencephalon development GO:0022037 89 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
multicellular organism growth GO:0035264 161 0.027
cell type specific apoptotic process GO:0097285 268 0.026
response to organonitrogen compound GO:0010243 246 0.026
generation of precursor metabolites and energy GO:0006091 103 0.026
response to extracellular stimulus GO:0009991 127 0.026
amino acid activation GO:0043038 1 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
transmission of nerve impulse GO:0019226 76 0.026
carboxylic acid transport GO:0046942 100 0.026
multicellular organismal signaling GO:0035637 91 0.025
cytoplasmic transport GO:0016482 234 0.025
response to monosaccharide GO:0034284 67 0.025
nucleoside catabolic process GO:0009164 206 0.025
neuron apoptotic process GO:0051402 142 0.025
cellular carbohydrate metabolic process GO:0044262 119 0.025
hexose metabolic process GO:0019318 98 0.025
organic acid biosynthetic process GO:0016053 86 0.024
neuronal action potential GO:0019228 54 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
nucleoside monophosphate metabolic process GO:0009123 85 0.024
nitrogen compound transport GO:0071705 271 0.024
regulation of organelle organization GO:0033043 289 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.023
fatty acid transmembrane transport GO:1902001 1 0.023
small molecule biosynthetic process GO:0044283 132 0.023
regulation of lymphocyte proliferation GO:0050670 117 0.023
response to peptide GO:1901652 136 0.023
regulation of hormone levels GO:0010817 211 0.023
asymmetric stem cell division GO:0098722 3 0.023
amine metabolic process GO:0009308 45 0.022
response to inorganic substance GO:0010035 96 0.022
endocytosis GO:0006897 168 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
fatty acid metabolic process GO:0006631 121 0.022
regulation of membrane potential GO:0042391 192 0.022
response to unfolded protein GO:0006986 21 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
regulation of neuron apoptotic process GO:0043523 122 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
regulation of cellular component biogenesis GO:0044087 181 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
positive regulation of protein modification process GO:0031401 299 0.021
cytokine production GO:0001816 319 0.021
skeletal system development GO:0001501 356 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
organic acid transport GO:0015849 101 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
anion transmembrane transport GO:0098656 71 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
organic acid catabolic process GO:0016054 51 0.020
cation transport GO:0006812 399 0.020
positive regulation of cellular catabolic process GO:0031331 148 0.020
lipid biosynthetic process GO:0008610 179 0.020
cellular response to hormone stimulus GO:0032870 150 0.020
trna processing GO:0008033 11 0.020
membrane organization GO:0061024 245 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
endoplasmic reticulum unfolded protein response GO:0030968 19 0.020
nucleotide catabolic process GO:0009166 217 0.019
peptidyl amino acid modification GO:0018193 336 0.019
response to oxygen levels GO:0070482 62 0.019
homeostasis of number of cells GO:0048872 210 0.019
positive regulation of growth GO:0045927 104 0.019
alpha amino acid metabolic process GO:1901605 59 0.019
organic anion transport GO:0015711 137 0.019
lymphocyte proliferation GO:0046651 164 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.018
peptide metabolic process GO:0006518 46 0.018
lateral inhibition GO:0046331 1 0.018
regulation of secretion by cell GO:1903530 249 0.018
olfactory learning GO:0008355 2 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
peptide transport GO:0015833 133 0.018
positive regulation of leukocyte proliferation GO:0070665 73 0.018
cellular homeostasis GO:0019725 240 0.018
response to organic cyclic compound GO:0014070 198 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.017
cellular protein complex assembly GO:0043623 116 0.017
cell aging GO:0007569 35 0.017
trna metabolic process GO:0006399 11 0.017
sensory perception GO:0007600 245 0.017
negative regulation of neuron apoptotic process GO:0043524 92 0.017
lymphocyte apoptotic process GO:0070227 54 0.017
carbohydrate biosynthetic process GO:0016051 74 0.017
rna processing GO:0006396 105 0.017
positive regulation of cell projection organization GO:0031346 95 0.017
positive regulation of secretion by cell GO:1903532 114 0.017
ensheathment of neurons GO:0007272 76 0.017
protein ubiquitination GO:0016567 171 0.017
neuromuscular process GO:0050905 99 0.016
regulation of cell adhesion GO:0030155 154 0.016
positive regulation of cell development GO:0010720 237 0.016
muscle cell differentiation GO:0042692 261 0.016
positive regulation of fatty acid beta oxidation GO:0032000 1 0.016
regulation of translational elongation GO:0006448 4 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
leukocyte proliferation GO:0070661 172 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
alcohol metabolic process GO:0006066 116 0.016
glucose metabolic process GO:0006006 92 0.016
negative regulation of synapse assembly GO:0051964 3 0.016
glutamine family amino acid biosynthetic process GO:0009084 2 0.016
response to light stimulus GO:0009416 135 0.016
regulation of protein complex assembly GO:0043254 83 0.016
cell growth GO:0016049 130 0.016
response to oxygen radical GO:0000305 16 0.016
apoptotic signaling pathway GO:0097190 306 0.016
maintenance of location GO:0051235 89 0.016
nucleotide metabolic process GO:0009117 332 0.016
cellular response to peptide hormone stimulus GO:0071375 92 0.016
cation transmembrane transport GO:0098655 266 0.015
neuron death GO:0070997 154 0.015
action potential GO:0001508 78 0.015
response to acid chemical GO:0001101 111 0.015
b cell activation GO:0042113 161 0.015
positive regulation of lymphocyte proliferation GO:0050671 70 0.015
regulation of peptide transport GO:0090087 91 0.015
spermatid differentiation GO:0048515 115 0.015
regulation of ion transport GO:0043269 215 0.015
dna metabolic process GO:0006259 303 0.015
carbohydrate phosphorylation GO:0046835 15 0.015
cellular response to cytokine stimulus GO:0071345 189 0.014
cell adhesion GO:0007155 329 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
coenzyme metabolic process GO:0006732 52 0.014
peptide hormone secretion GO:0030072 109 0.014
organelle fusion GO:0048284 28 0.014
leukocyte mediated immunity GO:0002443 174 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
regulation of fatty acid beta oxidation GO:0031998 1 0.014
regulation of protein localization GO:0032880 231 0.014
axon ensheathment GO:0008366 76 0.014
negative regulation of protein modification process GO:0031400 163 0.014
regulation of transmembrane transport GO:0034762 128 0.014
glucose homeostasis GO:0042593 128 0.014
regulation of cell motility GO:2000145 236 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
plasma membrane long chain fatty acid transport GO:0015911 1 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
positive regulation of insulin secretion GO:0032024 26 0.014
lipid modification GO:0030258 65 0.013
ossification GO:0001503 216 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
nuclear transport GO:0051169 139 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
rna interference GO:0016246 2 0.013
response to lipopolysaccharide GO:0032496 128 0.013
gland development GO:0048732 330 0.013
negative regulation of neuron death GO:1901215 98 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
inflammatory response GO:0006954 244 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
cellular response to oxidative stress GO:0034599 76 0.013
striated muscle tissue development GO:0014706 293 0.013
cellular response to lipid GO:0071396 145 0.013
regulation of b cell activation GO:0050864 81 0.013
regulation of anatomical structure size GO:0090066 178 0.013
cellular response to peptide GO:1901653 92 0.013
dicarboxylic acid metabolic process GO:0043648 18 0.013
amide transport GO:0042886 138 0.013
regulation of glucose metabolic process GO:0010906 60 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
regulation of response to oxidative stress GO:1902882 19 0.013
leukocyte apoptotic process GO:0071887 71 0.013
spermatid development GO:0007286 108 0.013
positive regulation of secretion GO:0051047 130 0.013
response to starvation GO:0042594 65 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
positive regulation of cell motility GO:2000147 116 0.012
lymphocyte differentiation GO:0030098 242 0.012
protein kinase b signaling GO:0043491 74 0.012
hindbrain development GO:0030902 128 0.012
peptide secretion GO:0002790 114 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
autophagy GO:0006914 45 0.012
female gamete generation GO:0007292 74 0.012
lipid localization GO:0010876 126 0.012
immune effector process GO:0002252 321 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
regulation of cytokine production GO:0001817 266 0.012
anatomical structure homeostasis GO:0060249 145 0.012
protein localization to membrane GO:0072657 108 0.012
phospholipid metabolic process GO:0006644 87 0.012
cofactor metabolic process GO:0051186 80 0.012
cellular amide metabolic process GO:0043603 58 0.011
positive regulation of cell death GO:0010942 224 0.011
digestive system development GO:0055123 200 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
regulation of feeding behavior GO:0060259 3 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
immune response activating signal transduction GO:0002757 116 0.011
mapk cascade GO:0000165 281 0.011
response to temperature stimulus GO:0009266 55 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of neuron differentiation GO:0045664 281 0.011
hair cycle GO:0042633 90 0.011
protein catabolic process GO:0030163 221 0.011
fructose 6 phosphate metabolic process GO:0006002 1 0.011
regulation of neuron projection development GO:0010975 169 0.011
response to hypoxia GO:0001666 58 0.011
regulation of proteolysis GO:0030162 164 0.011
regulation of cell projection organization GO:0031344 206 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.011
regulation of response to wounding GO:1903034 189 0.011
molting cycle GO:0042303 90 0.011
renal system development GO:0072001 225 0.011
regulation of defense response GO:0031347 233 0.011
regulation of cell migration GO:0030334 219 0.011
regulation of protein maturation GO:1903317 96 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regulation of actin filament based process GO:0032970 99 0.011
glycerolipid metabolic process GO:0046486 122 0.011
cation homeostasis GO:0055080 212 0.011
regulation of hydrolase activity GO:0051336 246 0.010
protein import GO:0017038 101 0.010
response to nutrient levels GO:0031667 109 0.010
inner mitochondrial membrane organization GO:0007007 5 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
response to reactive oxygen species GO:0000302 56 0.010
mitochondrial protein processing GO:0034982 5 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
muscle system process GO:0003012 141 0.010
digestive tract development GO:0048565 190 0.010
nucleoside monophosphate catabolic process GO:0009125 59 0.010
negative regulation of fatty acid transport GO:2000192 1 0.010
hormone secretion GO:0046879 128 0.010
positive regulation of nervous system development GO:0051962 221 0.010
steroid metabolic process GO:0008202 119 0.010
metal ion homeostasis GO:0055065 189 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
cellular ion homeostasis GO:0006873 165 0.010
endomembrane system organization GO:0010256 147 0.010

Lonp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.063
disease of anatomical entity DOID:7 0 0.063
nervous system disease DOID:863 0 0.063
disease of metabolism DOID:0014667 0 0.045
neuropathy DOID:870 0 0.039
neuromuscular disease DOID:440 0 0.036
charcot marie tooth disease DOID:10595 0 0.032
neurodegenerative disease DOID:1289 0 0.021
acquired metabolic disease DOID:0060158 0 0.015
diabetes mellitus DOID:9351 0 0.013
carbohydrate metabolism disease DOID:0050013 0 0.013
glucose metabolism disease DOID:4194 0 0.013
inherited metabolic disorder DOID:655 0 0.010