Mus musculus

131 known processes

Lrp1

low density lipoprotein receptor-related protein 1

(Aliases: AI316852,A2mr,Lrp,CD91)

Lrp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sterol metabolic process GO:0016125 58 1.000
sterol transport GO:0015918 38 0.993
reverse cholesterol transport GO:0043691 6 0.971
positive regulation of sterol transport GO:0032373 9 0.970
phospholipid transfer to membrane GO:0006649 2 0.967
lipid transport GO:0006869 98 0.965
cholesterol metabolic process GO:0008203 56 0.957
sterol homeostasis GO:0055092 45 0.948
gland development GO:0048732 330 0.928
Mouse
positive regulation of endocytosis GO:0045807 42 0.928
regulation of cholesterol transport GO:0032374 17 0.922
positive regulation of phagocytosis GO:0050766 26 0.920
rho protein signal transduction GO:0007266 32 0.917
high density lipoprotein particle assembly GO:0034380 3 0.915
regulation of plasma lipoprotein particle levels GO:0097006 23 0.910
Mouse
regulation of cell migration GO:0030334 219 0.909
regulation of neuron differentiation GO:0045664 281 0.905
Mouse
regulation of sterol transport GO:0032371 17 0.902
positive regulation of triglyceride metabolic process GO:0090208 9 0.891
cholesterol transport GO:0030301 38 0.891
intracellular cholesterol transport GO:0032367 3 0.890
Mouse
amine metabolic process GO:0009308 45 0.890
regulation of beta amyloid clearance GO:1900221 1 0.886
regulation of phospholipid efflux GO:1902994 2 0.878
positive regulation of reverse cholesterol transport GO:1903064 1 0.878
regulation of cellular ketone metabolic process GO:0010565 66 0.875
phospholipid efflux GO:0033700 3 0.867
intracellular lipid transport GO:0032365 3 0.865
Mouse
response to low density lipoprotein particle GO:0055098 2 0.864
cytokine mediated signaling pathway GO:0019221 115 0.862
phospholipid catabolic process GO:0009395 5 0.858
lipoprotein metabolic process GO:0042157 43 0.853
lipoprotein biosynthetic process GO:0042158 33 0.853
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.844
Mouse
glutamate receptor signaling pathway GO:0007215 35 0.842
steroid metabolic process GO:0008202 119 0.841
neuron projection extension GO:1990138 64 0.835
developmental maturation GO:0021700 193 0.832
axonogenesis GO:0007409 274 0.818
Mouse
gastrulation GO:0007369 116 0.815
Mouse
regulation of ion transport GO:0043269 215 0.809
plasma lipoprotein particle clearance GO:0034381 13 0.803
Mouse
endocytosis GO:0006897 168 0.797
response to amino acid GO:0043200 37 0.797
Mouse
regulation of cellular catabolic process GO:0031329 242 0.779
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.779
kidney development GO:0001822 213 0.768
Mouse
regulation of smooth muscle cell migration GO:0014910 6 0.766
positive regulation of beta amyloid clearance GO:1900223 1 0.762
regulation of protein kinase activity GO:0045859 232 0.743
Mouse
chemotaxis GO:0006935 247 0.737
regulation of transferase activity GO:0051338 263 0.734
Mouse
lipid catabolic process GO:0016042 69 0.720
regulation of cell motility GO:2000145 236 0.717
urogenital system development GO:0001655 261 0.716
Mouse
regulation of glutamate receptor signaling pathway GO:1900449 16 0.707
skeletal system development GO:0001501 356 0.707
Mouse
negative regulation of cellular amide metabolic process GO:0034249 4 0.706
nucleobase containing small molecule metabolic process GO:0055086 352 0.706
regulation of cellular amine metabolic process GO:0033238 20 0.702
regulation of hydrolase activity GO:0051336 246 0.691
regulation of removal of superoxide radicals GO:2000121 4 0.679
cholesterol homeostasis GO:0042632 44 0.677
carbohydrate metabolic process GO:0005975 230 0.673
dendrite development GO:0016358 115 0.669
tissue migration GO:0090130 68 0.667
phagocytosis GO:0006909 66 0.667
cell migration in hindbrain GO:0021535 16 0.654
Mouse
positive regulation of cholesterol transport GO:0032376 9 0.644
positive regulation of nervous system development GO:0051962 221 0.637
Mouse
negative regulation of cell motility GO:2000146 61 0.629
regulation of mapk cascade GO:0043408 248 0.629
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.613
regulation of phosphatidylcholine catabolic process GO:0010899 2 0.605
cellular chemical homeostasis GO:0055082 215 0.601
Mouse
glycerolipid metabolic process GO:0046486 122 0.599
lipid localization GO:0010876 126 0.593
cellular response to peptide GO:1901653 92 0.581
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.579
positive regulation of mapk cascade GO:0043410 170 0.578
Mouse
intracellular sterol transport GO:0032366 3 0.578
Mouse
multicellular organismal homeostasis GO:0048871 164 0.575
Mouse
regulation of proteolysis GO:0030162 164 0.567
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.566
regulation of anatomical structure size GO:0090066 178 0.561
forebrain development GO:0030900 302 0.560
Mouse
membrane organization GO:0061024 245 0.559
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.558
positive regulation of apoptotic cell clearance GO:2000427 3 0.557
synaptic transmission GO:0007268 329 0.556
regulation of endocytosis GO:0030100 69 0.556
alcohol metabolic process GO:0006066 116 0.555
organonitrogen compound catabolic process GO:1901565 264 0.554
cognition GO:0050890 149 0.552
intestinal absorption GO:0050892 13 0.552
smooth muscle cell migration GO:0014909 10 0.551
positive regulation of lipid metabolic process GO:0045834 40 0.549
cellular response to acid chemical GO:0071229 68 0.548
organophosphate ester transport GO:0015748 28 0.542
nucleoside triphosphate catabolic process GO:0009143 205 0.539
carbohydrate derivative biosynthetic process GO:1901137 183 0.537
negative regulation of neuron projection development GO:0010977 50 0.537
Mouse
beta amyloid clearance GO:0097242 2 0.533
regulation of receptor activity GO:0010469 41 0.527
small gtpase mediated signal transduction GO:0007264 97 0.527
formation of radial glial scaffolds GO:0021943 4 0.512
Mouse
response to organic cyclic compound GO:0014070 198 0.512
Mouse
ion transmembrane transport GO:0034220 361 0.511
regulation of amyloid precursor protein catabolic process GO:1902991 8 0.511
sterol transmembrane transport GO:0035382 2 0.505
muscle tissue development GO:0060537 308 0.499
Mouse
purine ribonucleotide biosynthetic process GO:0009152 59 0.498
triglyceride metabolic process GO:0006641 51 0.495
striated muscle tissue development GO:0014706 293 0.493
Mouse
cellular response to nutrient levels GO:0031669 64 0.492
chemical homeostasis within a tissue GO:0048875 9 0.491
regulation of ras protein signal transduction GO:0046578 114 0.483
ribose phosphate biosynthetic process GO:0046390 59 0.477
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 3 0.476
mapk cascade GO:0000165 281 0.474
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.471
glycerolipid catabolic process GO:0046503 16 0.469
positive regulation of cholesterol efflux GO:0010875 9 0.462
positive regulation of phospholipid transport GO:2001140 4 0.460
regulation of neuron projection development GO:0010975 169 0.454
Mouse
regulation of phospholipid transport GO:2001138 4 0.453
long term synaptic potentiation GO:0060291 25 0.451
digestive system development GO:0055123 200 0.448
Mouse
nucleotide metabolic process GO:0009117 332 0.448
cellular amino acid metabolic process GO:0006520 103 0.447
positive regulation of growth GO:0045927 104 0.445
positive regulation of protein modification process GO:0031401 299 0.443
Mouse
response to lipopolysaccharide GO:0032496 128 0.438
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.434
vacuole organization GO:0007033 38 0.430
epithelial tube morphogenesis GO:0060562 303 0.429
Mouse
cellular amine metabolic process GO:0044106 44 0.427
lung development GO:0030324 164 0.425
regulation of organelle organization GO:0033043 289 0.424
glycoprotein biosynthetic process GO:0009101 89 0.422
cellular lipid catabolic process GO:0044242 52 0.421
cell substrate adhesion GO:0031589 130 0.421
organic anion transport GO:0015711 137 0.419
response to molecule of bacterial origin GO:0002237 143 0.411
dephosphorylation GO:0016311 129 0.411
purine nucleotide metabolic process GO:0006163 302 0.410
beta amyloid metabolic process GO:0050435 14 0.403
transmembrane transport GO:0055085 412 0.401
positive regulation of protein phosphorylation GO:0001934 242 0.401
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.401
ribonucleotide metabolic process GO:0009259 291 0.396
cholesterol efflux GO:0033344 24 0.396
regulation of lipid storage GO:0010883 20 0.394
acylglycerol metabolic process GO:0006639 55 0.392
myeloid cell differentiation GO:0030099 233 0.391
regulation of phagocytosis GO:0050764 33 0.391
regulation of extent of cell growth GO:0061387 52 0.390
neutral lipid metabolic process GO:0006638 57 0.389
cell maturation GO:0048469 127 0.385
maintenance of location GO:0051235 89 0.385
positive regulation of apoptotic process GO:0043065 217 0.384
Mouse
regulation of innate immune response GO:0045088 91 0.384
defense response to other organism GO:0098542 197 0.382
hindbrain radial glia guided cell migration GO:0021932 12 0.382
Mouse
inflammatory response GO:0006954 244 0.381
positive regulation of kinase activity GO:0033674 155 0.380
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.379
lipid storage GO:0019915 36 0.375
organophosphate biosynthetic process GO:0090407 122 0.369
positive regulation of proteolysis GO:0045862 85 0.368
Mouse
photoreceptor cell maintenance GO:0045494 19 0.368
regulation of cell projection organization GO:0031344 206 0.364
Mouse
negative regulation of cellular component organization GO:0051129 194 0.363
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.363
triglyceride catabolic process GO:0019433 9 0.362
skeletal system morphogenesis GO:0048705 203 0.361
Mouse
hematopoietic stem cell migration GO:0035701 1 0.361
axon guidance GO:0007411 141 0.356
regulation of kinase activity GO:0043549 249 0.355
Mouse
ameboidal type cell migration GO:0001667 128 0.354
Mouse
plasma lipoprotein particle organization GO:0071827 11 0.351
response to acid chemical GO:0001101 111 0.350
Mouse
cdc42 protein signal transduction GO:0032488 0 0.348
cell type specific apoptotic process GO:0097285 268 0.345
digestive tract development GO:0048565 190 0.341
Mouse
stem cell maintenance GO:0019827 130 0.341
Mouse
regulation of engulfment of apoptotic cell GO:1901074 2 0.340
lipid homeostasis GO:0055088 63 0.339
negative regulation of cell development GO:0010721 169 0.337
Mouse
small molecule catabolic process GO:0044282 71 0.335
purine ribonucleoside catabolic process GO:0046130 205 0.334
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.333
protein lipid complex subunit organization GO:0071825 12 0.333
phospholipid transport GO:0015914 21 0.324
glycerophospholipid metabolic process GO:0006650 71 0.324
response to growth factor GO:0070848 198 0.318
response to peptide hormone GO:0043434 127 0.316
regulation of blood coagulation GO:0030193 28 0.314
positive regulation of apoptotic signaling pathway GO:2001235 95 0.311
liver development GO:0001889 66 0.310
camera type eye development GO:0043010 266 0.309
Mouse
glucose homeostasis GO:0042593 128 0.307
Mouse
negative regulation of cell migration GO:0030336 59 0.305
cerebellar granule cell precursor tangential migration GO:0021935 1 0.305
regulation of body fluid levels GO:0050878 162 0.304
telencephalon development GO:0021537 186 0.304
Mouse
regulation of fatty acid metabolic process GO:0019217 28 0.304
epidermis development GO:0008544 187 0.303
Mouse
triglyceride biosynthetic process GO:0019432 17 0.302
cellular response to growth factor stimulus GO:0071363 197 0.301
cellular response to cytokine stimulus GO:0071345 189 0.298
protein localization to membrane GO:0072657 108 0.296
Mouse
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.295
cellular response to hormone stimulus GO:0032870 150 0.292
germ cell development GO:0007281 185 0.289
positive regulation of ion transport GO:0043270 65 0.288
ribonucleoside triphosphate catabolic process GO:0009203 199 0.286
apoptotic cell clearance GO:0043277 17 0.286
regulation of rho protein signal transduction GO:0035023 71 0.285
ribonucleotide biosynthetic process GO:0009260 59 0.284
organonitrogen compound biosynthetic process GO:1901566 192 0.283
memory GO:0007613 58 0.282
skin development GO:0043588 220 0.281
Mouse
protein catabolic process GO:0030163 221 0.280
Mouse
anatomical structure homeostasis GO:0060249 145 0.280
Mouse
negative regulation of beta amyloid formation GO:1902430 4 0.279
purine nucleoside triphosphate catabolic process GO:0009146 203 0.275
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.272
positive regulation of phospholipid efflux GO:1902995 2 0.272
angiogenesis GO:0001525 201 0.267
Mouse
cellular lipid metabolic process GO:0044255 323 0.266
protein localization to organelle GO:0033365 185 0.264
Mouse
positive regulation of phosphoprotein phosphatase activity GO:0032516 1 0.262
regulation of reverse cholesterol transport GO:1903062 1 0.261
forebrain cell migration GO:0021885 58 0.261
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.261
neutral lipid catabolic process GO:0046461 11 0.255
blood vessel morphogenesis GO:0048514 285 0.255
ribonucleoside metabolic process GO:0009119 245 0.253
bone development GO:0060348 120 0.253
Mouse
engulfment of apoptotic cell GO:0043652 3 0.251
regulation of cholesterol biosynthetic process GO:0045540 8 0.251
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.250
cholesterol esterification GO:0034435 3 0.249
protein localization to nucleus GO:0034504 121 0.248
Mouse
digestive tract morphogenesis GO:0048546 147 0.246
Mouse
cellular ketone metabolic process GO:0042180 84 0.245
regulation of membrane potential GO:0042391 192 0.245
purine containing compound biosynthetic process GO:0072522 70 0.245
positive regulation of axon extension GO:0045773 20 0.242
protein processing GO:0016485 163 0.240
intestinal cholesterol absorption GO:0030299 5 0.240
cellular response to organonitrogen compound GO:0071417 145 0.236
membrane depolarization GO:0051899 64 0.234
regulation of phagocytosis engulfment GO:0060099 5 0.233
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.232
response to peptide GO:1901652 136 0.232
learning or memory GO:0007611 148 0.232
positive regulation of tissue remodeling GO:0034105 19 0.231
Mouse
neuron projection guidance GO:0097485 141 0.231
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.228
regulation of apoptotic signaling pathway GO:2001233 197 0.221
regulation of cytoskeleton organization GO:0051493 122 0.220
negative regulation of cell proliferation GO:0008285 296 0.218
Mouse
skeletal muscle organ development GO:0060538 163 0.217
neuron apoptotic process GO:0051402 142 0.216
response to organonitrogen compound GO:0010243 246 0.215
Mouse
macromolecule glycosylation GO:0043413 55 0.214
positive regulation of protein kinase b signaling GO:0051897 32 0.212
glycosyl compound catabolic process GO:1901658 206 0.211
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.210
regulation of phospholipid catabolic process GO:0060696 2 0.209
regulation of response to wounding GO:1903034 189 0.208
organic hydroxy compound transport GO:0015850 93 0.208
leukocyte migration GO:0050900 124 0.206
morphogenesis of a branching epithelium GO:0061138 193 0.205
Mouse
regulation of lipase activity GO:0060191 15 0.202
sensory perception GO:0007600 245 0.200
cellular response to peptide hormone stimulus GO:0071375 92 0.199
epithelial cell migration GO:0010631 63 0.199
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.199
macromolecule catabolic process GO:0009057 281 0.199
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.194
Mouse
regulation of postsynaptic membrane potential GO:0060078 48 0.194
regulation of fat cell differentiation GO:0045598 81 0.194
Mouse
myeloid leukocyte migration GO:0097529 57 0.193
positive regulation of cell activation GO:0050867 158 0.192
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.189
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.188
very low density lipoprotein particle remodeling GO:0034372 1 0.188
tissue homeostasis GO:0001894 115 0.188
Mouse
retina development in camera type eye GO:0060041 119 0.188
Mouse
renal system development GO:0072001 225 0.188
Mouse
peptide metabolic process GO:0006518 46 0.187
cholesterol import GO:0070508 2 0.185
t cell activation GO:0042110 289 0.184
cell chemotaxis GO:0060326 81 0.184
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.184
Mouse
positive regulation of cell migration GO:0030335 109 0.183
locomotory behavior GO:0007626 195 0.182
actin filament organization GO:0007015 113 0.180
nucleoside triphosphate metabolic process GO:0009141 230 0.180
tissue remodeling GO:0048771 102 0.178
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.178
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.178
protein lipidation GO:0006497 28 0.177
embryonic placenta development GO:0001892 98 0.177
cholesterol storage GO:0010878 4 0.177
chromatin modification GO:0016568 187 0.177
urea cycle GO:0000050 2 0.176
protein glycosylation GO:0006486 55 0.176
ras protein signal transduction GO:0007265 77 0.174
lymphocyte migration GO:0072676 26 0.174
cerebral cortex cell migration GO:0021795 44 0.170
Mouse
positive regulation of cell development GO:0010720 237 0.167
nucleoside catabolic process GO:0009164 206 0.167
monocarboxylic acid metabolic process GO:0032787 191 0.167
positive regulation of lymphocyte activation GO:0051251 140 0.167
negative regulation of growth GO:0045926 99 0.166
negative regulation of smooth muscle cell migration GO:0014912 2 0.165
positive regulation of lipid transport GO:0032370 22 0.164
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.164
cellular response to lipid GO:0071396 145 0.163
endothelial cell migration GO:0043542 44 0.163
negative regulation of intracellular signal transduction GO:1902532 167 0.162
nucleotide catabolic process GO:0009166 217 0.161
cell adhesion GO:0007155 329 0.160
regulation of peptidase activity GO:0052547 96 0.160
pallium development GO:0021543 120 0.160
Mouse
anion transport GO:0006820 177 0.159
negative regulation of neuron differentiation GO:0045665 101 0.159
Mouse
regulation of lymphocyte activation GO:0051249 240 0.157
guanosine containing compound metabolic process GO:1901068 144 0.156
cyclic purine nucleotide metabolic process GO:0052652 43 0.155
innate immune response GO:0045087 157 0.155
metanephric mesenchymal cell migration GO:0035789 2 0.154
somitogenesis GO:0001756 69 0.154
Mouse
hindbrain development GO:0030902 128 0.153
Mouse
positive regulation of neuron projection development GO:0010976 79 0.152
nucleoside phosphate metabolic process GO:0006753 338 0.152
regionalization GO:0003002 337 0.149
Mouse
positive regulation of dendrite development GO:1900006 21 0.148
ribose phosphate metabolic process GO:0019693 291 0.147
single organism cell adhesion GO:0098602 156 0.147
regulation of insulin receptor signaling pathway GO:0046626 21 0.147
blood vessel endothelial cell migration GO:0043534 23 0.146
ribonucleotide catabolic process GO:0009261 208 0.145
nephron development GO:0072006 109 0.144
purine ribonucleotide metabolic process GO:0009150 290 0.144
acylglycerol homeostasis GO:0055090 16 0.144
response to insulin GO:0032868 100 0.144
regulation of amyloid precursor protein biosynthetic process GO:0042984 3 0.142
phosphatidylinositol mediated signaling GO:0048015 41 0.141
glycolipid metabolic process GO:0006664 25 0.140
extrinsic apoptotic signaling pathway GO:0097191 126 0.140
sterol esterification GO:0034434 3 0.140
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.138
negative regulation of lipid catabolic process GO:0050995 6 0.138
muscle system process GO:0003012 141 0.138
purine nucleotide biosynthetic process GO:0006164 65 0.138
apoptotic signaling pathway GO:0097190 306 0.138
positive regulation of cell motility GO:2000147 116 0.137
regulation of triglyceride biosynthetic process GO:0010866 10 0.137
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.136
action potential GO:0001508 78 0.136
peptidyl tyrosine modification GO:0018212 145 0.135
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.134
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.133
Mouse
circadian rhythm GO:0007623 114 0.132
regulation of lipid catabolic process GO:0050994 15 0.131
developmental growth involved in morphogenesis GO:0060560 138 0.131
Mouse
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.131
amyloid precursor protein biosynthetic process GO:0042983 3 0.131
neuromuscular process controlling balance GO:0050885 59 0.131
adult behavior GO:0030534 135 0.129
regulation of homeostatic process GO:0032844 182 0.129
Mouse
purine nucleoside catabolic process GO:0006152 205 0.129
purine nucleoside metabolic process GO:0042278 241 0.128
regulation of axon extension GO:0030516 43 0.128
aromatic compound catabolic process GO:0019439 286 0.128
regulation of protein targeting GO:1903533 61 0.127
substrate dependent cell migration GO:0006929 18 0.127
positive regulation of smooth muscle cell migration GO:0014911 4 0.127
protein import into nucleus GO:0006606 95 0.127
Mouse
regulation of multi organism process GO:0043900 111 0.126
purine containing compound metabolic process GO:0072521 311 0.125
positive regulation of phospholipase c activity GO:0010863 2 0.125
lung alveolus development GO:0048286 45 0.125
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.124
positive regulation of triglyceride catabolic process GO:0010898 3 0.124
respiratory system development GO:0060541 190 0.123
Mouse
hepaticobiliary system development GO:0061008 67 0.123
regulation of inflammatory response GO:0050727 147 0.121
positive regulation of lipid storage GO:0010884 10 0.120
response to nutrient levels GO:0031667 109 0.120
Mouse
glycosylation GO:0070085 62 0.120
embryonic organ morphogenesis GO:0048562 276 0.119
Mouse
cellular response to insulin stimulus GO:0032869 78 0.119
positive regulation of organelle organization GO:0010638 128 0.118
salivary gland development GO:0007431 37 0.118
nitrogen cycle metabolic process GO:0071941 3 0.118
hexose metabolic process GO:0019318 98 0.118
neuron migration GO:0001764 122 0.118
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.117
neuron death GO:0070997 154 0.116
beta amyloid formation GO:0034205 9 0.116
high density lipoprotein particle remodeling GO:0034375 4 0.116
cellular amide metabolic process GO:0043603 58 0.115
negative regulation of cell projection organization GO:0031345 56 0.114
Mouse
regulation of cytokine production GO:0001817 266 0.113
heterocycle catabolic process GO:0046700 280 0.113
developmental cell growth GO:0048588 84 0.113
regulation of nucleotide metabolic process GO:0006140 169 0.112
regulation of cell size GO:0008361 72 0.112
brown fat cell differentiation GO:0050873 36 0.111
ossification GO:0001503 216 0.110
Mouse
plasma lipoprotein particle assembly GO:0034377 6 0.110
response to reactive oxygen species GO:0000302 56 0.109
dna metabolic process GO:0006259 303 0.108
muscle cell migration GO:0014812 19 0.108
low density lipoprotein particle clearance GO:0034383 8 0.107
Mouse
regulation of cellular component size GO:0032535 121 0.107
cyclic nucleotide biosynthetic process GO:0009190 44 0.107
regulation of cdc42 protein signal transduction GO:0032489 5 0.107
neuron neuron synaptic transmission GO:0007270 69 0.106
regulation of stress activated mapk cascade GO:0032872 69 0.105
nephron morphogenesis GO:0072028 69 0.105
epithelium migration GO:0090132 63 0.104
regulation of beta amyloid formation GO:1902003 8 0.104
nucleoside monophosphate metabolic process GO:0009123 85 0.103
regulation of synaptic transmission glutamatergic GO:0051966 19 0.103
positive regulation of phosphatase activity GO:0010922 4 0.102
visual perception GO:0007601 52 0.102
glycosaminoglycan biosynthetic process GO:0006024 15 0.101
regulation of ion transmembrane transport GO:0034765 119 0.101
negative regulation of cellular amine metabolic process GO:0033239 1 0.101
regulation of t cell activation GO:0050863 170 0.100
regulation of defense response GO:0031347 233 0.100
anatomical structure arrangement GO:0048532 20 0.100
sphingolipid metabolic process GO:0006665 45 0.100
response to retinoic acid GO:0032526 56 0.099
neurotransmitter gated ion channel clustering GO:0072578 6 0.098
white fat cell differentiation GO:0050872 15 0.098
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.098
nephron epithelium development GO:0072009 92 0.098
positive regulation of engulfment of apoptotic cell GO:1901076 1 0.097
synapse organization GO:0050808 125 0.096
Mouse
morphogenesis of a polarized epithelium GO:0001738 37 0.096
gliogenesis GO:0042063 141 0.096
Mouse
cyclic nucleotide metabolic process GO:0009187 59 0.096
regulation of cholesterol efflux GO:0010874 13 0.096
purine containing compound catabolic process GO:0072523 213 0.096
exocrine system development GO:0035272 45 0.095
sensory perception of light stimulus GO:0050953 54 0.095
regulation of intestinal cholesterol absorption GO:0030300 4 0.094
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.094
Mouse
negative regulation of axon guidance GO:1902668 8 0.094
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.093
embryonic skeletal system morphogenesis GO:0048704 91 0.093
mesenchyme development GO:0060485 152 0.092
Mouse
layer formation in cerebral cortex GO:0021819 13 0.092
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.092
cellular response to organic cyclic compound GO:0071407 87 0.092
protein kinase b signaling GO:0043491 74 0.091
hemostasis GO:0007599 78 0.091
positive regulation of chromatin modification GO:1903310 28 0.091
cholesterol catabolic process GO:0006707 5 0.091
negative regulation of axon extension GO:0030517 19 0.090
cytokine production involved in immune response GO:0002367 34 0.090
telencephalon cell migration GO:0022029 55 0.090
Mouse
cellular response to prostaglandin stimulus GO:0071379 2 0.090
glycosyl compound metabolic process GO:1901657 246 0.089
alcohol catabolic process GO:0046164 16 0.089
positive regulation of protein localization to cell surface GO:2000010 2 0.089
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.088
coagulation GO:0050817 78 0.088
regulation of cholesterol esterification GO:0010872 2 0.088
carbohydrate derivative catabolic process GO:1901136 231 0.088
leukocyte chemotaxis GO:0030595 69 0.087

Lrp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.955
inherited metabolic disorder DOID:655 0 0.928
lipid metabolism disorder DOID:3146 0 0.752
immune system disease DOID:2914 0 0.507
disease of anatomical entity DOID:7 0 0.507
lymphatic system disease DOID:75 0 0.507
musculoskeletal system disease DOID:17 0 0.250
connective tissue disease DOID:65 0 0.250
lysosomal storage disease DOID:3211 0 0.159
bone disease DOID:0080001 0 0.152
lipid storage disease DOID:9455 0 0.149
sphingolipidosis DOID:1927 0 0.149
sensory system disease DOID:0050155 0 0.131
eye and adnexa disease DOID:1492 0 0.131
nervous system disease DOID:863 0 0.131
retinal disease DOID:5679 0 0.117
eye disease DOID:5614 0 0.117
central nervous system disease DOID:331 0 0.099
tauopathy DOID:680 0 0.099
neurodegenerative disease DOID:1289 0 0.099