Mus musculus

0 known processes

Lrwd1

leucine-rich repeats and WD repeat domain containing 1

(Aliases: AW548074,1200011O22Rik,AU042569,Orca)

Lrwd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.468
microtubule based process GO:0007017 236 0.225
chromatin organization GO:0006325 206 0.201
Human
dna repair GO:0006281 107 0.181
heterocycle catabolic process GO:0046700 280 0.138
microtubule cytoskeleton organization GO:0000226 157 0.125
cellular response to dna damage stimulus GO:0006974 207 0.103
aromatic compound catabolic process GO:0019439 286 0.096
macromolecule catabolic process GO:0009057 281 0.093
nucleoside metabolic process GO:0009116 246 0.091
purine containing compound metabolic process GO:0072521 311 0.084
regulation of mitotic cell cycle phase transition GO:1901990 73 0.084
nucleoside phosphate catabolic process GO:1901292 222 0.080
regulation of cell cycle process GO:0010564 160 0.079
mitotic cell cycle GO:0000278 195 0.077
regulation of organelle organization GO:0033043 289 0.069
organelle assembly GO:0070925 177 0.067
cellular nitrogen compound catabolic process GO:0044270 280 0.067
rna catabolic process GO:0006401 29 0.067
regulation of chromosome organization GO:0033044 83 0.065
negative regulation of cell cycle GO:0045786 123 0.063
purine ribonucleoside metabolic process GO:0046128 241 0.062
negative regulation of gene expression epigenetic GO:0045814 15 0.062
protein localization to organelle GO:0033365 185 0.062
Human
negative regulation of cell proliferation GO:0008285 296 0.061
purine containing compound catabolic process GO:0072523 213 0.059
purine nucleoside triphosphate metabolic process GO:0009144 226 0.059
gene silencing GO:0016458 38 0.057
nucleobase containing small molecule metabolic process GO:0055086 352 0.055
purine nucleoside metabolic process GO:0042278 241 0.054
regulation of cell cycle GO:0051726 281 0.051
organic cyclic compound catabolic process GO:1901361 295 0.051
histone methylation GO:0016571 71 0.050
cellular amino acid metabolic process GO:0006520 103 0.049
base excision repair GO:0006284 9 0.049
cilium morphogenesis GO:0060271 102 0.049
positive regulation of protein modification process GO:0031401 299 0.049
mitotic cell cycle process GO:1903047 159 0.048
purine ribonucleoside catabolic process GO:0046130 205 0.046
positive regulation of organelle organization GO:0010638 128 0.046
positive regulation of cellular amine metabolic process GO:0033240 5 0.046
regulation of mitotic cell cycle GO:0007346 126 0.045
negative regulation of cellular protein metabolic process GO:0032269 247 0.045
protein alkylation GO:0008213 81 0.043
methylation GO:0032259 134 0.042
protein methylation GO:0006479 81 0.042
endocytosis GO:0006897 168 0.042
chromatin modification GO:0016568 187 0.040
regulation of cell cycle phase transition GO:1901987 77 0.040
establishment of organelle localization GO:0051656 122 0.039
negative regulation of organelle organization GO:0010639 90 0.039
nucleoside catabolic process GO:0009164 206 0.037
negative regulation of molecular function GO:0044092 258 0.037
glycosyl compound metabolic process GO:1901657 246 0.036
purine nucleotide catabolic process GO:0006195 211 0.036
ribonucleoside triphosphate metabolic process GO:0009199 220 0.035
negative regulation of phosphorylation GO:0042326 166 0.035
purine ribonucleotide catabolic process GO:0009154 208 0.034
regulation of protein localization GO:0032880 231 0.034
protein dna complex subunit organization GO:0071824 28 0.034
organelle localization GO:0051640 179 0.033
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.033
positive regulation of cell cycle phase transition GO:1901989 17 0.032
small gtpase mediated signal transduction GO:0007264 97 0.032
dna integrity checkpoint GO:0031570 28 0.032
cellular protein complex assembly GO:0043623 116 0.032
cell cycle checkpoint GO:0000075 47 0.032
purine nucleoside catabolic process GO:0006152 205 0.031
regulation of histone modification GO:0031056 56 0.031
recombinational repair GO:0000725 21 0.031
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.031
regulation of actin nucleation GO:0051125 4 0.031
negative regulation of mitotic cell cycle GO:0045930 58 0.031
cellular component assembly involved in morphogenesis GO:0010927 139 0.031
regulation of histone h3 k4 methylation GO:0051569 12 0.031
purine nucleoside triphosphate catabolic process GO:0009146 203 0.030
negative regulation of cell cycle process GO:0010948 69 0.030
regulation of protein kinase activity GO:0045859 232 0.029
regulation of histone methylation GO:0031060 30 0.029
negative regulation of protein modification process GO:0031400 163 0.029
positive regulation of chromosome organization GO:2001252 33 0.029
nucleotide metabolic process GO:0009117 332 0.028
regulation of anatomical structure size GO:0090066 178 0.028
regulation of protein transport GO:0051223 163 0.028
nucleotide catabolic process GO:0009166 217 0.028
negative regulation of cell cycle phase transition GO:1901988 48 0.027
histone modification GO:0016570 159 0.027
germ cell development GO:0007281 185 0.027
negative regulation of phosphate metabolic process GO:0045936 184 0.027
camera type eye development GO:0043010 266 0.027
positive regulation of histone modification GO:0031058 28 0.026
meiotic cell cycle process GO:1903046 77 0.025
positive regulation of cell death GO:0010942 224 0.025
regulation of intracellular transport GO:0032386 159 0.025
histone lysine methylation GO:0034968 50 0.025
regulation of hydrolase activity GO:0051336 246 0.025
regulation of ras gtpase activity GO:0032318 88 0.024
regulation of multi organism process GO:0043900 111 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
cytoplasmic transport GO:0016482 234 0.024
macromolecule methylation GO:0043414 120 0.024
carbohydrate derivative catabolic process GO:1901136 231 0.023
immune effector process GO:0002252 321 0.023
organelle fission GO:0048285 170 0.023
covalent chromatin modification GO:0016569 163 0.023
regulation of chromatin modification GO:1903308 57 0.023
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.023
nuclear division GO:0000280 158 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
negative regulation of cell development GO:0010721 169 0.022
cellular amine metabolic process GO:0044106 44 0.022
operant conditioning GO:0035106 2 0.022
innate immune response GO:0045087 157 0.022
protein polymerization GO:0051258 57 0.022
homeostasis of number of cells GO:0048872 210 0.022
rna interference GO:0016246 2 0.021
regulation of ras protein signal transduction GO:0046578 114 0.021
regulation of chromatin organization GO:1902275 57 0.021
regulation of cellular amino acid metabolic process GO:0006521 5 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
intracellular protein transport GO:0006886 204 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
amine metabolic process GO:0009308 45 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
positive regulation of hydrolase activity GO:0051345 148 0.020
peptidyl lysine modification GO:0018205 77 0.020
sensory organ morphogenesis GO:0090596 242 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
viral gene expression GO:0019080 3 0.020
histone h3 k4 methylation GO:0051568 23 0.020
dna replication GO:0006260 52 0.019
nitrogen compound transport GO:0071705 271 0.019
skeletal system development GO:0001501 356 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
meiosis i GO:0007127 60 0.019
organism emergence from protective structure GO:0071684 4 0.019
regulation of proteolysis GO:0030162 164 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
cell division GO:0051301 120 0.018
mitotic cell cycle checkpoint GO:0007093 31 0.018
ras protein signal transduction GO:0007265 77 0.018
regulation of cytoplasmic transport GO:1903649 112 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.017
hatching GO:0035188 4 0.017
metencephalon development GO:0022037 89 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
chromosome segregation GO:0007059 48 0.017
gtp catabolic process GO:0006184 143 0.017
organophosphate catabolic process GO:0046434 232 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
viral transcription GO:0019083 3 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
nucleobase biosynthetic process GO:0046112 3 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.016
positive regulation of histone methylation GO:0031062 16 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
single organism nuclear import GO:1902593 95 0.016
regulation of nucleotide catabolic process GO:0030811 122 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
regulation of kinase activity GO:0043549 249 0.016
g1 s transition of mitotic cell cycle GO:0000082 57 0.016
guanosine containing compound metabolic process GO:1901068 144 0.016
cellular ketone metabolic process GO:0042180 84 0.016
nuclear transport GO:0051169 139 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
response to organic cyclic compound GO:0014070 198 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.015
protein ubiquitination GO:0016567 171 0.015
regulation of adaptive immune response GO:0002819 90 0.015
dna geometric change GO:0032392 7 0.015
negative regulation of histone h3 k9 methylation GO:0051573 4 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
calcium ion transport GO:0006816 159 0.015
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
metaphase plate congression GO:0051310 2 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
positive regulation of chromosome segregation GO:0051984 4 0.015
skin development GO:0043588 220 0.015
cellular response to organic cyclic compound GO:0071407 87 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
regulation of mapk cascade GO:0043408 248 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
divalent inorganic cation transport GO:0072511 178 0.015
dna recombination GO:0006310 92 0.015
protein processing GO:0016485 163 0.014
atp catabolic process GO:0006200 55 0.014
rna dependent dna replication GO:0006278 3 0.014
positive regulation of gtp catabolic process GO:0033126 85 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
peptidyl lysine acetylation GO:0018394 45 0.014
gene silencing by rna GO:0031047 19 0.014
regulation of cell activation GO:0050865 289 0.014
nucleoside monophosphate metabolic process GO:0009123 85 0.014
maintenance of location GO:0051235 89 0.014
response to lipopolysaccharide GO:0032496 128 0.014
protein localization to nucleus GO:0034504 121 0.014
negative regulation of nervous system development GO:0051961 156 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
regulation of protein binding GO:0043393 60 0.013
cell cycle g1 s phase transition GO:0044843 57 0.013
retina development in camera type eye GO:0060041 119 0.013
regulation of viral transcription GO:0046782 3 0.013
regulation of cellular ketone metabolic process GO:0010565 66 0.013
response to ionizing radiation GO:0010212 42 0.013
leukocyte differentiation GO:0002521 342 0.013
chemotaxis GO:0006935 247 0.013
rna 3 end processing GO:0031123 20 0.013
meiotic nuclear division GO:0007126 115 0.013
response to growth factor GO:0070848 198 0.013
stem cell differentiation GO:0048863 268 0.013
regulation of binding GO:0051098 111 0.013
nuclear dna replication GO:0033260 3 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
transmembrane transport GO:0055085 412 0.013
gland development GO:0048732 330 0.013
stem cell development GO:0048864 219 0.012
establishment of vesicle localization GO:0051650 81 0.012
male gamete generation GO:0048232 285 0.012
negative regulation of protein processing GO:0010955 79 0.012
spermatogenesis GO:0007283 284 0.012
lateral inhibition GO:0046331 1 0.012
protein targeting GO:0006605 143 0.012
female gamete generation GO:0007292 74 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
membrane organization GO:0061024 245 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
sulfur compound metabolic process GO:0006790 100 0.012
viral life cycle GO:0019058 36 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
mapk cascade GO:0000165 281 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
regulation of protein catabolic process GO:0042176 108 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
nucleotide excision repair GO:0006289 13 0.012
developmental maturation GO:0021700 193 0.012
digestive tract development GO:0048565 190 0.012
mitotic nuclear division GO:0007067 48 0.012
gtp metabolic process GO:0046039 144 0.012
protein catabolic process GO:0030163 221 0.012
purine nucleotide metabolic process GO:0006163 302 0.011
leukocyte migration GO:0050900 124 0.011
dna modification GO:0006304 50 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
Human
response to oxidative stress GO:0006979 123 0.011
multi multicellular organism process GO:0044706 109 0.011
divalent metal ion transport GO:0070838 172 0.011
b cell activation GO:0042113 161 0.011
axon guidance GO:0007411 141 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
connective tissue development GO:0061448 179 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
lymphocyte proliferation GO:0046651 164 0.011
cilium assembly GO:0042384 81 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
apoptotic signaling pathway GO:0097190 306 0.011
regulation of defense response GO:0031347 233 0.011
intracellular mrna localization GO:0008298 4 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.011
negative regulation of multi organism process GO:0043901 68 0.011
placenta development GO:0001890 140 0.011
regulation of transferase activity GO:0051338 263 0.011
posttranscriptional gene silencing GO:0016441 10 0.011
oocyte anterior posterior axis specification GO:0007314 2 0.011
dna damage checkpoint GO:0000077 26 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
positive regulation of viral genome replication GO:0045070 2 0.010
protein localization to chromosome GO:0034502 6 0.010
Human
cell junction organization GO:0034330 77 0.010
dna duplex unwinding GO:0032508 7 0.010
internal protein amino acid acetylation GO:0006475 42 0.010
regulation of cell projection organization GO:0031344 206 0.010
response to transforming growth factor beta GO:0071559 88 0.010
regulation of receptor binding GO:1900120 4 0.010
peptidyl amino acid modification GO:0018193 336 0.010
viral process GO:0016032 41 0.010
leukocyte mediated immunity GO:0002443 174 0.010
positive regulation of chromatin modification GO:1903310 28 0.010

Lrwd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
large intestine cancer DOID:5672 0 0.038
gastrointestinal system cancer DOID:3119 0 0.038
intestinal cancer DOID:10155 0 0.038
cancer DOID:162 0 0.038
disease of cellular proliferation DOID:14566 0 0.038
organ system cancer DOID:0050686 0 0.038
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
central nervous system disease DOID:331 0 0.016
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
neurodegenerative disease DOID:1289 0 0.011