Mus musculus

107 known processes

Lta

lymphotoxin A

(Aliases: MGC117668,LTalpha,TNF-beta,Ltx,Tnfsf1b,LT,LT-[a],Tnfb,LT[a],TNFSF1,LT-alpha,hlb382)

Lta biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lymph node development GO:0048535 18 0.998
positive regulation of chronic inflammatory response GO:0002678 4 0.995
positive regulation of icosanoid secretion GO:0032305 7 0.994
Mouse
icosanoid secretion GO:0032309 12 0.994
Mouse
interleukin 5 secretion GO:0072603 2 0.993
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.993
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.993
immunoglobulin secretion GO:0048305 17 0.992
Mouse
regulation of corticotropin releasing hormone secretion GO:0043397 2 0.992
Mouse
interleukin 10 secretion GO:0072608 4 0.991
prostaglandin transport GO:0015732 7 0.990
Mouse
lymphocyte differentiation GO:0030098 242 0.988
Mouse
positive regulation of translational initiation by iron GO:0045994 2 0.988
Mouse
regulation of translational initiation by iron GO:0006447 2 0.987
Mouse
i kappab kinase nf kappab signaling GO:0007249 85 0.985
Mouse
somatic diversification of immunoglobulins GO:0016445 43 0.984
Mouse
positive regulation of adaptive immune response GO:0002821 61 0.982
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.982
regulation of fever generation by regulation of prostaglandin secretion GO:0071810 2 0.982
Mouse
positive regulation of translational initiation GO:0045948 4 0.981
Mouse
regulation of b cell proliferation GO:0030888 39 0.979
positive regulation of leukocyte proliferation GO:0070665 73 0.977
regulation of b cell activation GO:0050864 81 0.977
cytokine mediated signaling pathway GO:0019221 115 0.975
Mouse
regulation of interleukin 6 production GO:0032675 55 0.972
Mouse
regulation of cell activation GO:0050865 289 0.967
Mouse
regulation of t cell activation GO:0050863 170 0.965
Mouse
positive regulation of fever generation by positive regulation of prostaglandin secretion GO:0071812 2 0.964
Mouse
extracellular structure organization GO:0043062 148 0.962
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.952
cellular response to amino acid stimulus GO:0071230 29 0.950
Mouse
interleukin 13 secretion GO:0072611 2 0.949
positive regulation of osteoclast development GO:2001206 3 0.945
Mouse
growth of symbiont involved in interaction with host GO:0044116 23 0.941
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.937
tumor necrosis factor mediated signaling pathway GO:0033209 13 0.935
Mouse
positive regulation of cell activation GO:0050867 158 0.932
Mouse
fatty acid derivative transport GO:1901571 14 0.931
Mouse
lymphocyte mediated immunity GO:0002449 139 0.931
heat generation GO:0031649 13 0.927
Mouse
lymphocyte migration GO:0072676 26 0.924
Mouse
pigment metabolic process GO:0042440 32 0.924
Fly
negative regulation of growth of symbiont in host GO:0044130 19 0.924
b cell activation GO:0042113 161 0.923
Mouse
regulation of fatty acid transport GO:2000191 10 0.923
Mouse
corticotropin releasing hormone secretion GO:0043396 2 0.920
Mouse
leukocyte mediated immunity GO:0002443 174 0.919
necroptotic signaling pathway GO:0097527 3 0.918
Mouse
acid secretion GO:0046717 33 0.918
Mouse
regulation of chronic inflammatory response to antigenic stimulus GO:0002874 3 0.911
ensheathment of neurons GO:0007272 76 0.911
immunoglobulin mediated immune response GO:0016064 69 0.910
alpha beta t cell proliferation GO:0046633 21 0.906
positive regulation of b cell activation GO:0050871 49 0.906
positive regulation of fever generation GO:0031622 6 0.903
Mouse
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.903
Mouse
regulation of interleukin 13 secretion GO:2000665 2 0.901
positive regulation of isotype switching to igg isotypes GO:0048304 7 0.899
positive regulation of interleukin 12 production GO:0032735 21 0.899
negative regulation of interleukin 10 secretion GO:2001180 2 0.898
t cell migration GO:0072678 19 0.898
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.895
interleukin 12 production GO:0032615 32 0.895
positive regulation of lymphocyte activation GO:0051251 140 0.894
Mouse
regulation of cytokine production GO:0001817 266 0.892
regulation of response to wounding GO:1903034 189 0.892
negative regulation of interleukin 13 production GO:0032696 2 0.890
defense response to bacterium GO:0042742 119 0.885
negative regulation of multi organism process GO:0043901 68 0.884
metal ion homeostasis GO:0055065 189 0.883
Mouse
regulation of anion transport GO:0044070 27 0.878
Mouse
dna recombination GO:0006310 92 0.876
Mouse
positive regulation of b cell proliferation GO:0030890 24 0.876
regulation of interleukin 10 secretion GO:2001179 4 0.875
carboxylic acid transport GO:0046942 100 0.873
Mouse
positive regulation of t cell activation GO:0050870 101 0.870
Mouse
cytokine production involved in immune response GO:0002367 34 0.870
leukocyte proliferation GO:0070661 172 0.869
Mouse
t cell receptor signaling pathway GO:0050852 46 0.869
leukocyte differentiation GO:0002521 342 0.868
Mouse
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.866
Mouse
regulation of adaptive immune response GO:0002819 90 0.861
response to tumor necrosis factor GO:0034612 26 0.860
Mouse
positive regulation of myoblast differentiation GO:0045663 8 0.859
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.854
Mouse Fly
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.850
positive regulation of immune effector process GO:0002699 107 0.849
growth of symbiont in host GO:0044117 23 0.848
positive regulation of lymphocyte proliferation GO:0050671 70 0.848
t cell proliferation GO:0042098 120 0.844
fever generation GO:0001660 7 0.841
Mouse
positive regulation of organic acid transport GO:0032892 11 0.840
Mouse
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.839
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.838
Mouse
positive regulation of humoral immune response mediated by circulating immunoglobulin GO:0002925 6 0.838
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.833
lymphocyte costimulation GO:0031294 15 0.828
Mouse
programmed necrotic cell death GO:0097300 28 0.826
Mouse
negative regulation of interleukin 5 production GO:0032714 4 0.823
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.822
Mouse
positive regulation of leukocyte mediated immunity GO:0002705 70 0.817
positive regulation of heat generation GO:0031652 7 0.813
Mouse
t cell chemotaxis GO:0010818 6 0.808
Mouse
humoral immune response GO:0006959 57 0.800
skeletal muscle fiber development GO:0048741 58 0.799
Mouse
cytokine production GO:0001816 319 0.797
positive regulation of lipid transport GO:0032370 22 0.795
Mouse
somatic cell dna recombination GO:0016444 51 0.792
Mouse
regulation of leukocyte mediated immunity GO:0002703 104 0.788
dephosphorylation GO:0016311 129 0.784
Mouse
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.782
regulation of lymphocyte mediated immunity GO:0002706 84 0.775
axon ensheathment GO:0008366 76 0.771
dendritic cell differentiation GO:0097028 26 0.769
acute phase response GO:0006953 10 0.765
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.763
regulation of lymphocyte activation GO:0051249 240 0.763
Mouse
action potential GO:0001508 78 0.762
regulation of establishment of protein localization GO:0070201 181 0.759
Mouse
regulation of t cell proliferation GO:0042129 92 0.757
regulation of acute inflammatory response GO:0002673 27 0.751
Mouse
regulation of skeletal muscle fiber development GO:0048742 36 0.750
Mouse
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.749
positive regulation of corticotropin releasing hormone secretion GO:0051466 1 0.748
Mouse
regulation of cytokine secretion GO:0050707 61 0.748
regulation of lipid transport GO:0032368 36 0.746
Mouse
regulation of fever generation GO:0031620 6 0.745
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.740
adaptive immune response GO:0002250 155 0.737
regulation of cytokine biosynthetic process GO:0042035 59 0.736
regulation of immunoglobulin secretion GO:0051023 12 0.730
Mouse
cellular response to tumor necrosis factor GO:0071356 21 0.724
Mouse
cytokine biosynthetic process GO:0042089 68 0.722
glial cell apoptotic process GO:0034349 3 0.722
multicellular organismal signaling GO:0035637 91 0.719
organic acid transport GO:0015849 101 0.718
Mouse
positive regulation of b cell mediated immunity GO:0002714 26 0.718
production of molecular mediator of immune response GO:0002440 103 0.714
Mouse
lipid transport GO:0006869 98 0.710
Mouse
regulation of immunoglobulin mediated immune response GO:0002889 37 0.709
cell chemotaxis GO:0060326 81 0.708
Mouse
t cell activation GO:0042110 289 0.708
Mouse
regulation of cytokine secretion involved in immune response GO:0002739 4 0.707
positive regulation of interferon gamma production GO:0032729 39 0.707
b cell mediated immunity GO:0019724 71 0.702
regulation of interleukin 5 secretion GO:2000662 2 0.696
positive regulation of cytokine production GO:0001819 174 0.685
regulation of lymphocyte migration GO:2000401 14 0.673
Mouse
positive regulation of response to wounding GO:1903036 66 0.673
regulation of homeostatic process GO:0032844 182 0.668
Mouse
positive regulation of hair follicle development GO:0051798 6 0.666
Mouse
positive regulation of lymphocyte migration GO:2000403 11 0.665
Mouse
regulation of growth of symbiont in host GO:0044126 19 0.657
regulation of prostaglandin secretion GO:0032306 5 0.654
Mouse
positive regulation of fatty acid transport GO:2000193 8 0.651
Mouse
b cell activation involved in immune response GO:0002312 50 0.650
Mouse
t cell selection GO:0045058 34 0.650
protein localization to nucleus GO:0034504 121 0.648
Mouse
negative regulation of interleukin 13 secretion GO:2000666 1 0.641
defense response to other organism GO:0098542 197 0.640
isotype switching GO:0045190 36 0.632
Mouse
chronic inflammatory response GO:0002544 9 0.628
regulation of alpha beta t cell proliferation GO:0046640 18 0.628
negative regulation of t cell activation GO:0050868 65 0.626
protein kinase b signaling GO:0043491 74 0.617
Mouse
negative regulation of odontogenesis of dentin containing tooth GO:0042489 1 0.612
positive regulation of defense response GO:0031349 124 0.612
necroptotic process GO:0070266 21 0.609
Mouse
activation of cysteine type endopeptidase activity GO:0097202 27 0.605
Mouse
zymogen activation GO:0031638 41 0.597
Mouse
growth involved in symbiotic interaction GO:0044110 23 0.597
lymphocyte chemotaxis GO:0048247 10 0.595
Mouse
neuronal action potential GO:0019228 54 0.594
regulation of protein transport GO:0051223 163 0.592
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.591
positive regulation of cytokine secretion GO:0050715 41 0.584
immune response activating signal transduction GO:0002757 116 0.583
negative regulation of myoblast differentiation GO:0045662 18 0.581
Mouse
monocarboxylic acid transport GO:0015718 44 0.580
Mouse
t cell differentiation in thymus GO:0033077 77 0.580
cellular divalent inorganic cation homeostasis GO:0072503 127 0.579
alpha beta t cell activation GO:0046631 91 0.565
epithelial cell proliferation GO:0050673 174 0.564
Mouse
negative regulation of osteoblast differentiation GO:0045668 30 0.562
Mouse
regulation of branching involved in salivary gland morphogenesis GO:0060693 11 0.556
Mouse
activation of jun kinase activity GO:0007257 15 0.555
Mouse
immune effector process GO:0002252 321 0.553
t cell costimulation GO:0031295 14 0.552
Mouse
apoptotic signaling pathway GO:0097190 306 0.550
Mouse Fly
positive regulation of peptide hormone secretion GO:0090277 31 0.546
Mouse
positive regulation of prostaglandin secretion GO:0032308 5 0.543
Mouse
positive regulation of secretion GO:0051047 130 0.542
Mouse
positive regulation of peptide secretion GO:0002793 33 0.541
Mouse
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.537
Mouse
muscle cell development GO:0055001 133 0.535
Mouse
skin development GO:0043588 220 0.535
Mouse
alpha beta t cell differentiation GO:0046632 69 0.534
positive regulation of cytokine biosynthetic process GO:0042108 40 0.533
icosanoid transport GO:0071715 14 0.528
Mouse
b cell differentiation GO:0030183 78 0.527
Mouse
regulation of interleukin 2 production GO:0032663 28 0.527
positive regulation of jun kinase activity GO:0043507 30 0.522
Mouse
regulation of b cell mediated immunity GO:0002712 37 0.522
regulation of protein secretion GO:0050708 82 0.519
Mouse
positive regulation of jnk cascade GO:0046330 46 0.512
Mouse
protein homooligomerization GO:0051260 43 0.510
Mouse
translational initiation GO:0006413 24 0.502
Mouse
negative regulation of interleukin 5 secretion GO:2000663 1 0.497
mammary gland alveolus development GO:0060749 22 0.496
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.493
Mouse
positive regulation of t cell costimulation GO:2000525 2 0.482
stress activated protein kinase signaling cascade GO:0031098 81 0.479
Mouse Fly
regulation of peptide hormone secretion GO:0090276 75 0.477
Mouse
regulation of translational initiation GO:0006446 15 0.475
Mouse
defense response to virus GO:0051607 68 0.468
regulation of gliogenesis GO:0014013 50 0.468
Rat
osteoclast proliferation GO:0002158 4 0.467
Mouse
lymphocyte proliferation GO:0046651 164 0.466
cellular homeostasis GO:0019725 240 0.465
Fly
interspecies interaction between organisms GO:0044419 83 0.464
protein secretion GO:0009306 111 0.462
Mouse
positive regulation of secretion by cell GO:1903532 114 0.461
Mouse
alpha beta t cell activation involved in immune response GO:0002287 31 0.461
leukocyte activation involved in immune response GO:0002366 126 0.456
Mouse
hair follicle development GO:0001942 85 0.454
Mouse
prostaglandin secretion GO:0032310 5 0.453
Mouse
regulation of lymphocyte chemotaxis GO:1901623 6 0.453
Mouse
positive regulation of intracellular transport GO:0032388 70 0.452
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.447
Mouse
somatic diversification of immune receptors GO:0002200 53 0.446
Mouse
transmission of nerve impulse GO:0019226 76 0.444
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.443
dna metabolic process GO:0006259 303 0.441
Mouse
myeloid cell differentiation GO:0030099 233 0.436
Mouse
positive regulation of t cell differentiation GO:0045582 52 0.433
temperature homeostasis GO:0001659 26 0.432
Mouse
positive regulation of peptidase activity GO:0010952 49 0.426
Mouse
regulation of alpha beta t cell activation GO:0046634 53 0.425
cytokine secretion involved in immune response GO:0002374 6 0.423
cellular calcium ion homeostasis GO:0006874 119 0.421
cellular response to lipid GO:0071396 145 0.420
Mouse
skeletal muscle organ development GO:0060538 163 0.404
Mouse
odontogenesis GO:0042476 78 0.403
circadian rhythm GO:0007623 114 0.403
regulation of defense response GO:0031347 233 0.402
defense response to gram positive bacterium GO:0050830 50 0.400
regulation of humoral immune response GO:0002920 22 0.396
inflammatory response GO:0006954 244 0.395
calcium ion homeostasis GO:0055074 127 0.394
Mouse
cellular metal ion homeostasis GO:0006875 151 0.393
b cell apoptotic process GO:0001783 19 0.393
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.389
Mouse
immune complex clearance GO:0002434 2 0.387
positive regulation of cellular amine metabolic process GO:0033240 5 0.386
response to molecule of bacterial origin GO:0002237 143 0.383
Zebrafish Mouse Rat
regulation of protein serine threonine kinase activity GO:0071900 157 0.383
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.382
Mouse
lymphocyte activation involved in immune response GO:0002285 93 0.381
Mouse
regulation of immunoglobulin production GO:0002637 42 0.379
Mouse
negative regulation of alkaline phosphatase activity GO:0010693 3 0.378
Mouse
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.378
t cell differentiation GO:0030217 174 0.377
positive regulation of inflammatory response GO:0050729 47 0.370
fatty acid transport GO:0015908 28 0.366
Mouse
eosinophil degranulation GO:0043308 1 0.361
positive regulation of map kinase activity GO:0043406 84 0.359
Mouse
cytokine metabolic process GO:0042107 71 0.357
mammary gland lobule development GO:0061377 22 0.352
Mouse
muscle tissue development GO:0060537 308 0.351
Mouse
regulation of oligodendrocyte differentiation GO:0048713 23 0.347
syncytium formation by plasma membrane fusion GO:0000768 42 0.345
Mouse
protein maturation GO:0051604 176 0.343
Mouse
regulation of ion transport GO:0043269 215 0.343
Mouse
epidermis development GO:0008544 187 0.338
Mouse
antigen receptor mediated signaling pathway GO:0050851 64 0.337
positive regulation of cytokine production involved in immune response GO:0002720 19 0.333
cellular response to cytokine stimulus GO:0071345 189 0.328
Mouse
regulation of membrane potential GO:0042391 192 0.322
positive regulation of homeostatic process GO:0032846 64 0.320
Mouse
myelination GO:0042552 74 0.320
defense response to gram negative bacterium GO:0050829 28 0.319
Fly
engulfment of apoptotic cell GO:0043652 3 0.318
Fly
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.318
regulation of peptide transport GO:0090087 91 0.316
Mouse
cytoplasmic transport GO:0016482 234 0.315
Mouse
positive regulation of monocyte chemotaxis GO:0090026 2 0.315
positive regulation of ion transport GO:0043270 65 0.315
Mouse
regulation of cytokine production involved in immune response GO:0002718 26 0.313
positive regulation of hormone secretion GO:0046887 38 0.312
Mouse
positive regulation of gliogenesis GO:0014015 27 0.311
Rat
b cell proliferation GO:0042100 53 0.310
amide transport GO:0042886 138 0.309
Mouse
regulation of proteolysis GO:0030162 164 0.304
Mouse
mature dendritic cell differentiation GO:0097029 3 0.302
cytokine secretion GO:0050663 72 0.301
positive regulation of protein kinase b signaling GO:0051897 32 0.299
Mouse
gliogenesis GO:0042063 141 0.298
Rat
positive regulation of acute inflammatory response GO:0002675 16 0.298
Mouse
gland development GO:0048732 330 0.298
Zebrafish Mouse
negative regulation of glucose transport GO:0010829 9 0.298
Mouse
positive regulation of t cell migration GO:2000406 10 0.297
Mouse
transcription factor import into nucleus GO:0042991 26 0.297
Mouse
cell type specific apoptotic process GO:0097285 268 0.295
striated muscle cell development GO:0055002 125 0.295
Mouse
regulation of monocyte chemotaxis GO:0090025 3 0.295
regulation of intracellular transport GO:0032386 159 0.294
Mouse
regulation of glucose import GO:0046324 26 0.292
Mouse
t helper 2 cell cytokine production GO:0035745 4 0.292
regulation of t cell costimulation GO:2000523 2 0.289
cell cell recognition GO:0009988 44 0.285
regulation of protein localization GO:0032880 231 0.284
Mouse
positive regulation of interleukin 6 production GO:0032755 37 0.281
Mouse
cellular chemical homeostasis GO:0055082 215 0.280
regulation of inflammatory response GO:0050727 147 0.280
negative regulation of alpha beta t cell activation GO:0046636 18 0.277
regulation of interleukin 12 production GO:0032655 30 0.270
regulation of eosinophil degranulation GO:0043309 1 0.270
establishment of protein localization to organelle GO:0072594 118 0.270
Mouse
t cell extravasation GO:0072683 4 0.267
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.265
Mouse
regulation of monocyte extravasation GO:2000437 2 0.263
positive regulation of cytokine secretion involved in immune response GO:0002741 2 0.263
regulation of hair follicle development GO:0051797 9 0.262
Mouse
muscle fiber development GO:0048747 76 0.261
Mouse
positive regulation of stress activated mapk cascade GO:0032874 48 0.259
Mouse
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.259
positive regulation of monocyte extravasation GO:2000439 1 0.258
negative regulation of response to wounding GO:1903035 77 0.258
regulation of type 2 immune response GO:0002828 18 0.255
cellular ion homeostasis GO:0006873 165 0.254
anatomical structure homeostasis GO:0060249 145 0.252
Mouse Fly
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.249
acute inflammatory response GO:0002526 41 0.247
Mouse
regulation of jnk cascade GO:0046328 62 0.243
Mouse
oligodendrocyte differentiation GO:0048709 53 0.243
positive regulation of cell death GO:0010942 224 0.243
Mouse Rat
isotype switching to igg isotypes GO:0048291 10 0.240
regulation of stress activated mapk cascade GO:0032872 69 0.240
Mouse
regulation of myoblast differentiation GO:0045661 29 0.236
Mouse
epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 7 0.232
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.230
cellular amino acid metabolic process GO:0006520 103 0.230
cation homeostasis GO:0055080 212 0.225
Mouse
positive regulation of cell development GO:0010720 237 0.224
Mouse Rat
positive regulation of chronic inflammatory response to antigenic stimulus GO:0002876 2 0.224
eosinophil activation GO:0043307 1 0.221
regulation of interferon gamma production GO:0032649 57 0.218
extracellular matrix organization GO:0030198 147 0.216
Mouse
negative regulation of b cell proliferation GO:0030889 13 0.215
circadian temperature homeostasis GO:0060086 2 0.214
response to amino acid GO:0043200 37 0.214
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.214
Mouse
myeloid dendritic cell differentiation GO:0043011 16 0.214
regulation of vasculature development GO:1901342 88 0.214
antibacterial peptide production GO:0002778 2 0.214
regulation of t cell extravasation GO:2000407 3 0.212
mammary gland epithelial cell proliferation GO:0033598 24 0.212
Mouse
eosinophil mediated immunity GO:0002447 1 0.210
multicellular organismal homeostasis GO:0048871 164 0.210
Mouse
positive regulation of interleukin 2 production GO:0032743 19 0.207
negative regulation of b cell activation GO:0050869 27 0.205
positive regulation of translation GO:0045727 19 0.205
Mouse
negative regulation of ossification GO:0030279 49 0.202
Mouse
regulation of dna recombination GO:0000018 34 0.201
leukocyte migration GO:0050900 124 0.201
Mouse
chronic inflammatory response to antigenic stimulus GO:0002439 3 0.201
negative regulation of defense response GO:0031348 77 0.201
activation of immune response GO:0002253 138 0.200
posttranscriptional regulation of gene expression GO:0010608 155 0.200
Mouse
regulation of secretion GO:0051046 274 0.199
Mouse
positive regulation of leukocyte differentiation GO:1902107 86 0.199
Mouse
regulation of secretion by cell GO:1903530 249 0.199
Mouse
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.198
regulation of multi organism process GO:0043900 111 0.198
regulation of protein kinase activity GO:0045859 232 0.198
Mouse
helper t cell chemotaxis GO:0035704 1 0.197
regulation of glial cell differentiation GO:0045685 41 0.196
immune response regulating signaling pathway GO:0002764 125 0.196
regulation of isotype switching to igg isotypes GO:0048302 10 0.196
positive regulation of humoral immune response GO:0002922 11 0.195
anion transport GO:0006820 177 0.192
Mouse
neuromuscular synaptic transmission GO:0007274 16 0.190
Fly
striated muscle tissue development GO:0014706 293 0.189
Mouse
positive regulation of protein transport GO:0051222 93 0.189
Mouse
positive regulation of programmed cell death GO:0043068 218 0.188
Mouse Rat
eosinophil activation involved in immune response GO:0002278 1 0.188
cytosolic calcium ion homeostasis GO:0051480 70 0.186
regulation of epithelial cell proliferation GO:0050678 141 0.185
cell fate commitment GO:0045165 210 0.183
Fly
exocrine system development GO:0035272 45 0.179
Mouse
negative regulation of macrophage apoptotic process GO:2000110 3 0.178
response to acid chemical GO:0001101 111 0.177
Mouse
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.176
cellular response to dna damage stimulus GO:0006974 207 0.175
Mouse
hexose transport GO:0008645 56 0.171
Mouse
regulation of t helper 1 type immune response GO:0002825 17 0.171
t cell activation involved in immune response GO:0002286 43 0.167
regulation of peptide secretion GO:0002791 77 0.166
Mouse
neuron apoptotic process GO:0051402 142 0.165
positive regulation of chemotaxis GO:0050921 38 0.165
Mouse
regulation of dendritic cell chemotaxis GO:2000508 1 0.164
regulation of interleukin 6 biosynthetic process GO:0045408 11 0.163
cell activation involved in immune response GO:0002263 126 0.163
Mouse
gtp metabolic process GO:0046039 144 0.161
tissue remodeling GO:0048771 102 0.160
Mouse
stress activated mapk cascade GO:0051403 80 0.160
Mouse Fly
thymic t cell selection GO:0045061 22 0.159
positive regulation of osteoclast differentiation GO:0045672 15 0.159
Mouse
protein import GO:0017038 101 0.159
Mouse
t cell differentiation involved in immune response GO:0002292 30 0.159
positive regulation of kinase activity GO:0033674 155 0.158
Mouse
calcium ion transport GO:0006816 159 0.157
response to organonitrogen compound GO:0010243 246 0.156
Mouse
regulation of t cell chemotaxis GO:0010819 5 0.156
Mouse
positive regulation of protein secretion GO:0050714 52 0.156
syncytium formation GO:0006949 43 0.156
Mouse
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.154
regulation of protein localization to nucleus GO:1900180 60 0.153
Mouse
cdc42 protein signal transduction GO:0032488 0 0.153
microglial cell activation involved in immune response GO:0002282 1 0.153
molting cycle GO:0042303 90 0.153
Mouse
jnk cascade GO:0007254 72 0.152
Mouse Fly
regulation of b cell differentiation GO:0045577 23 0.152
regulation of hydrolase activity GO:0051336 246 0.152
Mouse
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.151
regulation of myotube differentiation GO:0010830 62 0.150
Mouse
interferon gamma production GO:0032609 67 0.149
negative regulation of muscle cell differentiation GO:0051148 33 0.149
Mouse
negative regulation of dephosphorylation GO:0035305 9 0.147
Mouse
negative regulation of cell activation GO:0050866 111 0.143
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.143
intracellular protein transport GO:0006886 204 0.140
Mouse
purine nucleoside catabolic process GO:0006152 205 0.140
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.139
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.138
regulation of endothelial cell chemotaxis GO:2001026 1 0.138
retinal cell programmed cell death GO:0046666 8 0.137
Mouse
regulation of organic acid transport GO:0032890 16 0.136
Mouse
cellular response to external stimulus GO:0071496 88 0.133
negative regulation of lymphocyte activation GO:0051250 91 0.132
negative regulation of immune effector process GO:0002698 55 0.132
positive regulation of alpha beta t cell activation GO:0046635 39 0.130
protein processing GO:0016485 163 0.130
Mouse
glucose metabolic process GO:0006006 92 0.129
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.127
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.127
Mouse
organophosphate catabolic process GO:0046434 232 0.126
peptide transport GO:0015833 133 0.125
Mouse
t cell mediated immunity GO:0002456 50 0.124
positive regulation of hydrolase activity GO:0051345 148 0.124
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.124
myotube cell development GO:0014904 60 0.123
Mouse
regulation of cytoplasmic transport GO:1903649 112 0.122
Mouse
telencephalon development GO:0021537 186 0.122
interleukin 6 production GO:0032635 58 0.121
Mouse
regulation of neutrophil chemotaxis GO:0090022 14 0.121
regulation of cell motility GO:2000145 236 0.121
Mouse
positive regulation of t cell proliferation GO:0042102 52 0.119
myeloid leukocyte activation GO:0002274 83 0.117
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.117
negative regulation of molecular function GO:0044092 258 0.117
Mouse
response to lipopolysaccharide GO:0032496 128 0.116
Zebrafish Mouse Rat
positive regulation of hair cycle GO:0042635 7 0.116
Mouse
regulation of dephosphorylation GO:0035303 18 0.116
Mouse
single organism cell adhesion GO:0098602 156 0.116
regulation of apoptotic signaling pathway GO:2001233 197 0.115
cellular response to molecule of bacterial origin GO:0071219 83 0.115
Mouse
positive regulation of t cell chemotaxis GO:0010820 5 0.115
Mouse
natural killer cell activation GO:0030101 44 0.115
protein complex localization GO:0031503 19 0.114
Mouse
asymmetric protein localization GO:0008105 11 0.114
Fly
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.114
negative regulation of eosinophil degranulation GO:0043310 1 0.113
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.113
glial cell differentiation GO:0010001 131 0.112
positive regulation of cytoplasmic transport GO:1903651 40 0.111
Mouse
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.111
cytosolic calcium ion transport GO:0060401 48 0.111
ossification GO:0001503 216 0.110
Mouse
regulation of jun kinase activity GO:0043506 40 0.110
Mouse
leukocyte apoptotic process GO:0071887 71 0.110
negative regulation of odontogenesis GO:0042483 3 0.109
regulation of cellular response to stress GO:0080135 159 0.109
Mouse
regulation of nucleocytoplasmic transport GO:0046822 73 0.108
Mouse
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.107
bone resorption GO:0045453 38 0.107
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.107
regulation of glucose transport GO:0010827 32 0.106
Mouse
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.106
regulation of alpha beta t cell differentiation GO:0046637 35 0.105
positive regulation of antigen processing and presentation GO:0002579 10 0.105
osteoclast development GO:0036035 9 0.105
Mouse
interleukin 1 secretion GO:0050701 16 0.105
regulation of t helper 2 cell cytokine production GO:2000551 3 0.104
b cell receptor signaling pathway GO:0050853 20 0.104

Lta disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.122
disease of anatomical entity DOID:7 0 0.122
musculoskeletal system disease DOID:17 0 0.122
connective tissue disease DOID:65 0 0.122