|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.999
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.998
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.998
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.998
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.998
|
Mouse |
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.998
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.997
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.997
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.995
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.995
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.993
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.992
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.991
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.990
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.990
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.988
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.986
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.986
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.985
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.984
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.984
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.982
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.980
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.979
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.978
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.978
|
|
|
|
histamine production involved in inflammatory response
|
GO:0002349 |
1 |
0.975
|
Rat |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.975
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.972
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.971
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.969
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.965
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.964
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.964
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.963
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.959
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.958
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.958
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.957
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.956
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.956
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.956
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.955
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.954
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.951
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.951
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.947
|
Mouse |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.947
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.946
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.945
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.944
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.941
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.939
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.938
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.938
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.937
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.936
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.931
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.930
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.929
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.929
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.927
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.922
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.919
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.915
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.914
|
|
|
|
positive regulation of leukocyte degranulation
|
GO:0043302 |
10 |
0.913
|
Mouse |
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.911
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.907
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.907
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.904
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.902
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.902
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.902
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.901
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.900
|
Mouse |
|
|
humoral immune response
|
GO:0006959 |
57 |
0.896
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.891
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.891
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.888
|
|
|
|
substrate dependent cell migration cell extension
|
GO:0006930 |
4 |
0.887
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.885
|
Fly |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.881
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.875
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.874
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.874
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.868
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.868
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.868
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.867
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.861
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.857
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.848
|
Mouse |
|
|
dendritic spine maintenance
|
GO:0097062 |
4 |
0.837
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.833
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.833
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.827
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.826
|
Mouse |
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.825
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.821
|
Mouse |
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.814
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.814
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.813
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.812
|
Mouse |
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.811
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.810
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.804
|
|
|
|
negative regulation of b cell mediated immunity
|
GO:0002713 |
7 |
0.803
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.798
|
Fly |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.797
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.796
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
8 |
0.796
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.784
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.779
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.779
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.778
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.777
|
Mouse |
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.771
|
Mouse |
|
|
granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0042253 |
2 |
0.770
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.769
|
Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.769
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.767
|
Mouse |
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.759
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.758
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.756
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.755
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.746
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.743
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.741
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.738
|
Mouse Worm |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.731
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.728
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.719
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.716
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.713
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.711
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.710
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.710
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.707
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.701
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.698
|
Mouse |
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.692
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.686
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.685
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.684
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.684
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.677
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.676
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.669
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.656
|
Mouse |
|
|
membrane organization
|
GO:0061024 |
245 |
0.655
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.654
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
15 |
0.647
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
22 |
0.646
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.646
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.642
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.640
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.626
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.624
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.621
|
Mouse |
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.612
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.609
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.609
|
|
|
|
regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045423 |
2 |
0.604
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.600
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.595
|
|
|
|
substrate dependent cell migration
|
GO:0006929 |
18 |
0.594
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.591
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.590
|
Mouse |
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.588
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.586
|
Mouse |
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.576
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.575
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.575
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.570
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.566
|
Mouse |
|
|
regulation of granulocyte macrophage colony stimulating factor production
|
GO:0032645 |
3 |
0.556
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
6 |
0.556
|
Mouse |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.554
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.553
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.550
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.537
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.522
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.518
|
Mouse Fly |
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.516
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.516
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.515
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.512
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.511
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.500
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.496
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.494
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.491
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.489
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.486
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.484
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.482
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.480
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.472
|
Mouse |
|
|
organelle assembly
|
GO:0070925 |
177 |
0.470
|
Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.469
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.468
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.448
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.448
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.446
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.441
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.440
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.433
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.430
|
Mouse |
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.429
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.427
|
Mouse |
|
|
cell communication by electrical coupling
|
GO:0010644 |
4 |
0.423
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.423
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.422
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.410
|
Mouse |
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.407
|
Fly |
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.405
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.404
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.401
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.396
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.391
|
|
|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
10 |
0.387
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
4 |
0.380
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.379
|
|
|
|
marginal zone b cell differentiation
|
GO:0002315 |
2 |
0.375
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.371
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.371
|
|
|
|
glycolipid metabolic process
|
GO:0006664 |
25 |
0.370
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.370
|
Fly |
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.369
|
|
|
|
negative regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002924 |
3 |
0.368
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.364
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.358
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.358
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.355
|
Fly |
|
|
acute inflammatory response to antigenic stimulus
|
GO:0002438 |
12 |
0.346
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.345
|
Mouse |
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.344
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.342
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.342
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.339
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
45 |
0.339
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
36 |
0.339
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.338
|
Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.337
|
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.337
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.335
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.334
|
Mouse Fly |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.332
|
Worm |
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.331
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.330
|
Mouse |
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.329
|
|
|
|
positive regulation of macrophage differentiation
|
GO:0045651 |
5 |
0.327
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.327
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.327
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.325
|
|
|
|
regulation of hypersensitivity
|
GO:0002883 |
10 |
0.325
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.325
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.318
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.318
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.314
|
Fly |
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.309
|
|
|
|
cell communication by chemical coupling
|
GO:0010643 |
2 |
0.309
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.308
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.307
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.307
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.305
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.304
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.304
|
Mouse |
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.299
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.293
|
|
|
|
positive regulation of mast cell activation
|
GO:0033005 |
12 |
0.291
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.290
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.288
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.287
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.286
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.285
|
Mouse Rat |
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.282
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.280
|
Mouse Worm |
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
20 |
0.280
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.278
|
Fly |
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.275
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.274
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.274
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.274
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.273
|
Worm |
|
|
regulation of b cell apoptotic process
|
GO:0002902 |
13 |
0.271
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.270
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.269
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.266
|
Mouse |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.265
|
Mouse |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.264
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.264
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.259
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.258
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.256
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.255
|
|
|
|
negative regulation of lymphocyte mediated immunity
|
GO:0002707 |
21 |
0.252
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.251
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.251
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.249
|
Mouse |
|
|
negative regulation of hypersensitivity
|
GO:0002884 |
3 |
0.248
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.247
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.243
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.241
|
|
|
|
granulocyte differentiation
|
GO:0030851 |
17 |
0.240
|
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.238
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.238
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.237
|
Mouse |
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.235
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.233
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.233
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.231
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.231
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.229
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.228
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.227
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.223
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.221
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.219
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.219
|
|
|
|
podosome assembly
|
GO:0071800 |
6 |
0.218
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.215
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.215
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.214
|
Fly |
|
|
positive regulation of granulocyte macrophage colony stimulating factor production
|
GO:0032725 |
3 |
0.214
|
|
|
|
granulocyte macrophage colony stimulating factor production
|
GO:0032604 |
3 |
0.214
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.214
|
Mouse |
|
|
positive regulation of mast cell activation involved in immune response
|
GO:0033008 |
10 |
0.213
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.212
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.210
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.207
|
Mouse |
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.207
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.205
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.202
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.201
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.201
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.200
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.198
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.198
|
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.197
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.197
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.197
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.196
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.193
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.193
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.191
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.188
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.187
|
|
|
|
regulation of granulocyte differentiation
|
GO:0030852 |
8 |
0.186
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.184
|
Rat |
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.183
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.183
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.182
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.181
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.181
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.179
|
Fly |
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.179
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.179
|
Worm |
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.179
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.178
|
|
|
|
regulation of neutrophil differentiation
|
GO:0045658 |
2 |
0.177
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.175
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.172
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.172
|
|
|
|
positive regulation of b cell differentiation
|
GO:0045579 |
13 |
0.171
|
|
|
|
interleukin 3 production
|
GO:0032632 |
3 |
0.170
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.170
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.169
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.169
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.168
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.167
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.167
|
Fly |
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.167
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.165
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.165
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
14 |
0.164
|
Mouse |
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.164
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.163
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.163
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.162
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.162
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.161
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.160
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.158
|
Mouse |
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.158
|
|
|
|
glycosphingolipid metabolic process
|
GO:0006687 |
18 |
0.157
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.157
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.156
|
Mouse |
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.155
|
|
|
|
positive regulation of cholesterol transport
|
GO:0032376 |
9 |
0.154
|
|
|
|
dendritic spine organization
|
GO:0097061 |
26 |
0.154
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
8 |
0.153
|
Mouse |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.153
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.152
|
Mouse |
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.152
|
Rat |
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.152
|
Mouse |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.152
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.152
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.151
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.147
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.147
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.147
|
Mouse |
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.146
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.146
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
18 |
0.145
|
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.143
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.142
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.142
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
15 |
0.142
|
|
|
|
positive regulation of lipid transport
|
GO:0032370 |
22 |
0.142
|
|
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.142
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.142
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.139
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.139
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.139
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.139
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.139
|
Rat |
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.138
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.137
|
Mouse Fly |
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.137
|
Fly |
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.137
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.137
|
Mouse |
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.136
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
10 |
0.135
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
23 |
0.135
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.133
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.133
|
Fly |
|
|
triglyceride metabolic process
|
GO:0006641 |
51 |
0.133
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.133
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.133
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.132
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.132
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.132
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.132
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.131
|
Mouse |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.131
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.130
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.129
|
|
|
|
negative regulation of cell adhesion mediated by integrin
|
GO:0033629 |
2 |
0.127
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.127
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.127
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.127
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.126
|
Mouse |
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.125
|
Fly |
|
|
icosanoid metabolic process
|
GO:0006690 |
33 |
0.124
|
|
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.124
|
|
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.124
|
|
|
|
liposaccharide metabolic process
|
GO:1903509 |
27 |
0.123
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.123
|
|
|
|
myd88 dependent toll like receptor signaling pathway
|
GO:0002755 |
7 |
0.123
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.122
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.122
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.121
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.121
|
|
|
|
negative regulation of humoral immune response
|
GO:0002921 |
6 |
0.121
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.121
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.120
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.120
|
Mouse |
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.120
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.118
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.117
|
Mouse |
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.117
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.117
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.116
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.116
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.116
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
45 |
0.115
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.115
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.115
|
Mouse |
|
|
regulation of gamma delta t cell differentiation
|
GO:0045586 |
9 |
0.114
|
Mouse |
|
|
zymogen activation
|
GO:0031638 |
41 |
0.113
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.113
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.112
|
Mouse |
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.112
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.112
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.112
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.111
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.108
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.108
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.108
|
Mouse |
|
|
positive regulation of hypersensitivity
|
GO:0002885 |
7 |
0.108
|
|
|
|
positive regulation of granulocyte differentiation
|
GO:0030854 |
3 |
0.107
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.107
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.107
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
11 |
0.106
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.106
|
Mouse Rat |
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.106
|
Mouse |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.106
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.105
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.104
|
|
