Mus musculus

119 known processes

Lyst

lysosomal trafficking regulator

(Aliases: bg,beige,D13Sfk13)

Lyst biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of melanosome localization GO:0032401 11 1.000
pigment cell differentiation GO:0050931 27 1.000
pigmentation GO:0043473 71 1.000
melanocyte differentiation GO:0030318 25 1.000
pigment granule localization GO:0051875 13 1.000
melanosome localization GO:0032400 12 1.000
developmental pigmentation GO:0048066 40 1.000
pigment accumulation GO:0043476 1 1.000
melanosome transport GO:0032402 11 1.000
pigment metabolic process GO:0042440 32 0.999
secondary metabolic process GO:0019748 18 0.998
pigment biosynthetic process GO:0046148 26 0.998
cellular pigmentation GO:0033059 20 0.997
pigment granule transport GO:0051904 12 0.997
vesicle localization GO:0051648 86 0.995
melanin metabolic process GO:0006582 12 0.995
neuroepithelial cell differentiation GO:0060563 37 0.988
regulation of pigment cell differentiation GO:0050932 7 0.979
melanin biosynthetic process GO:0042438 10 0.975
secondary metabolite biosynthetic process GO:0044550 11 0.974
establishment of pigment granule localization GO:0051905 12 0.972
pigment granule organization GO:0048753 9 0.965
vesicle organization GO:0016050 60 0.964
organelle localization GO:0051640 179 0.959
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.954
melanosome organization GO:0032438 8 0.951
phenol containing compound biosynthetic process GO:0046189 21 0.951
lysosome organization GO:0007040 21 0.942
establishment of vesicle localization GO:0051650 81 0.941
natural killer cell degranulation GO:0043320 3 0.907
establishment of organelle localization GO:0051656 122 0.888
negative regulation of secondary metabolite biosynthetic process GO:1900377 2 0.867
microtubule based movement GO:0007018 84 0.860
synaptic transmission GO:0007268 329 0.827
organic hydroxy compound metabolic process GO:1901615 203 0.817
regulation of leukocyte differentiation GO:1902105 159 0.779
regulation of body fluid levels GO:0050878 162 0.777
blood coagulation GO:0007596 76 0.761
microtubule based transport GO:0010970 50 0.729
lytic vacuole organization GO:0080171 21 0.708
hemostasis GO:0007599 78 0.657
secretory granule localization GO:0032252 3 0.631
response to organonitrogen compound GO:0010243 246 0.625
regulation of developmental pigmentation GO:0048070 14 0.617
cellular nitrogen compound catabolic process GO:0044270 280 0.608
coagulation GO:0050817 78 0.592
cellular amino acid metabolic process GO:0006520 103 0.559
glycosyl compound catabolic process GO:1901658 206 0.553
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.550
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity GO:0031585 2 0.539
nucleoside triphosphate metabolic process GO:0009141 230 0.538
cytoplasmic transport GO:0016482 234 0.534
Human
ribonucleotide metabolic process GO:0009259 291 0.530
aromatic compound catabolic process GO:0019439 286 0.525
positive regulation of developmental pigmentation GO:0048087 6 0.523
leukocyte differentiation GO:0002521 342 0.515
ribonucleoside triphosphate catabolic process GO:0009203 199 0.514
natural killer cell activation involved in immune response GO:0002323 10 0.509
purine nucleotide metabolic process GO:0006163 302 0.501
cellular lipid metabolic process GO:0044255 323 0.498
organophosphate catabolic process GO:0046434 232 0.497
spermatogenesis GO:0007283 284 0.493
dna metabolic process GO:0006259 303 0.470
organic hydroxy compound biosynthetic process GO:1901617 77 0.468
anterograde axon cargo transport GO:0008089 20 0.467
organonitrogen compound catabolic process GO:1901565 264 0.466
membrane organization GO:0061024 245 0.466
maintenance of location GO:0051235 89 0.464
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 2 0.463
sphingolipid metabolic process GO:0006665 45 0.462
positive regulation of pigment cell differentiation GO:0050942 5 0.448
protein targeting GO:0006605 143 0.447
negative regulation of melanin biosynthetic process GO:0048022 2 0.444
synaptic vesicle localization GO:0097479 59 0.444
inorganic ion transmembrane transport GO:0098660 234 0.443
fatty acid metabolic process GO:0006631 121 0.442
purine nucleoside catabolic process GO:0006152 205 0.440
long term synaptic potentiation GO:0060291 25 0.439
transmembrane transport GO:0055085 412 0.438
heterocycle catabolic process GO:0046700 280 0.437
regulation of cell activation GO:0050865 289 0.436
regulation of cellular catabolic process GO:0031329 242 0.435
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.426
monocarboxylic acid metabolic process GO:0032787 191 0.426
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.425
cation transport GO:0006812 399 0.423
organic cyclic compound catabolic process GO:1901361 295 0.418
glycosyl compound metabolic process GO:1901657 246 0.416
nucleotide metabolic process GO:0009117 332 0.415
lipid localization GO:0010876 126 0.414
cytoskeleton dependent intracellular transport GO:0030705 50 0.414
positive regulation of cellular catabolic process GO:0031331 148 0.411
regulation of hydrolase activity GO:0051336 246 0.407
regulation of membrane potential GO:0042391 192 0.402
nucleoside metabolic process GO:0009116 246 0.398
ion transmembrane transport GO:0034220 361 0.395
purine ribonucleotide metabolic process GO:0009150 290 0.388
alpha beta t cell differentiation GO:0046632 69 0.387
regulation of cellular amine metabolic process GO:0033238 20 0.386
reactive oxygen species biosynthetic process GO:1903409 8 0.385
positive regulation of lymphocyte activation GO:0051251 140 0.383
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 11 0.382
carbohydrate derivative catabolic process GO:1901136 231 0.380
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.380
release of cytochrome c from mitochondria GO:0001836 23 0.378
ribonucleoside triphosphate metabolic process GO:0009199 220 0.377
nucleoside catabolic process GO:0009164 206 0.376
lymphocyte differentiation GO:0030098 242 0.368
amine metabolic process GO:0009308 45 0.365
reactive oxygen species metabolic process GO:0072593 84 0.362
guanosine containing compound catabolic process GO:1901069 144 0.360
regulation of t cell activation GO:0050863 170 0.357
ribonucleotide catabolic process GO:0009261 208 0.351
ribonucleoside catabolic process GO:0042454 206 0.350
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.349
purine ribonucleoside metabolic process GO:0046128 241 0.349
purine containing compound metabolic process GO:0072521 311 0.342
cellular ion homeostasis GO:0006873 165 0.340
positive regulation of hydrolase activity GO:0051345 148 0.339
regulation of reactive oxygen species metabolic process GO:2000377 40 0.336
purine containing compound catabolic process GO:0072523 213 0.331
glial cell apoptotic process GO:0034349 3 0.330
leukocyte homeostasis GO:0001776 79 0.321
nucleotide catabolic process GO:0009166 217 0.319
regulation of ion transport GO:0043269 215 0.318
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 11 0.317
purine nucleotide catabolic process GO:0006195 211 0.316
inorganic cation transmembrane transport GO:0098662 207 0.316
secretion of lysosomal enzymes GO:0033299 6 0.311
learning GO:0007612 98 0.311
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.311
purine ribonucleotide catabolic process GO:0009154 208 0.308
anterograde synaptic vesicle transport GO:0048490 15 0.301
positive regulation of nervous system development GO:0051962 221 0.296
neuronal action potential GO:0019228 54 0.293
phenol containing compound metabolic process GO:0018958 60 0.289
cellular response to peptide GO:1901653 92 0.287
cellular amine metabolic process GO:0044106 44 0.286
calcium ion transmembrane transport GO:0070588 85 0.286
alpha amino acid metabolic process GO:1901605 59 0.278
signal transduction in absence of ligand GO:0038034 55 0.278
positive regulation of phagocytosis GO:0050766 26 0.275
modification by symbiont of host morphology or physiology GO:0044003 4 0.275
regulation of lymphocyte activation GO:0051249 240 0.273
purine nucleoside triphosphate metabolic process GO:0009144 226 0.271
peptidyl amino acid modification GO:0018193 336 0.269
response to peptide hormone GO:0043434 127 0.268
gtp metabolic process GO:0046039 144 0.267
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 3 0.266
synaptic vesicle transport GO:0048489 57 0.264
apoptotic mitochondrial changes GO:0008637 48 0.262
rho protein signal transduction GO:0007266 32 0.259
regulation of endocytosis GO:0030100 69 0.259
myeloid cell differentiation GO:0030099 233 0.259
nucleoside phosphate metabolic process GO:0006753 338 0.258
response to peptide GO:1901652 136 0.255
cellular macromolecule catabolic process GO:0044265 206 0.252
cognition GO:0050890 149 0.252
positive regulation of cell activation GO:0050867 158 0.252
regulation of alpha beta t cell differentiation GO:0046637 35 0.251
cellular homeostasis GO:0019725 240 0.249
regulation of vesicle mediated transport GO:0060627 139 0.249
gland development GO:0048732 330 0.248
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.248
male gamete generation GO:0048232 285 0.247
divalent metal ion transport GO:0070838 172 0.244
cell fate commitment GO:0045165 210 0.242
protein localization to membrane GO:0072657 108 0.242
urogenital system development GO:0001655 261 0.239
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 4 0.239
regulation of myeloid leukocyte differentiation GO:0002761 58 0.239
microtubule based process GO:0007017 236 0.237
intracellular protein transport GO:0006886 204 0.236
homeostasis of number of cells GO:0048872 210 0.235
regulation of melanocyte differentiation GO:0045634 7 0.232
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.231
positive regulation of gtpase activity GO:0043547 85 0.230
gtp catabolic process GO:0006184 143 0.227
cation transmembrane transport GO:0098655 266 0.226
lymphocyte homeostasis GO:0002260 64 0.226
apoptotic signaling pathway GO:0097190 306 0.225
b cell activation GO:0042113 161 0.225
regulation of purine nucleotide metabolic process GO:1900542 169 0.224
cation homeostasis GO:0055080 212 0.224
guanosine containing compound metabolic process GO:1901068 144 0.218
t cell differentiation GO:0030217 174 0.218
peptidyl serine phosphorylation GO:0018105 74 0.217
regulation of b cell differentiation GO:0045577 23 0.216
development of primary sexual characteristics GO:0045137 143 0.216
regulation of lymphocyte differentiation GO:0045619 107 0.215
axon ensheathment GO:0008366 76 0.213
axonogenesis GO:0007409 274 0.213
response to endoplasmic reticulum stress GO:0034976 53 0.211
regulation of exocytosis GO:0017157 61 0.203
ribonucleoside metabolic process GO:0009119 245 0.203
protein maturation GO:0051604 176 0.203
regulation of map kinase activity GO:0043405 120 0.201
cellular response to organonitrogen compound GO:0071417 145 0.199
purine nucleoside triphosphate catabolic process GO:0009146 203 0.198
myeloid leukocyte differentiation GO:0002573 119 0.197
myelination GO:0042552 74 0.193
regulation of ion transmembrane transporter activity GO:0032412 54 0.192
regulation of nucleoside metabolic process GO:0009118 130 0.188
endosome organization GO:0007032 9 0.182
peptidyl serine modification GO:0018209 83 0.179
nucleoside phosphate catabolic process GO:1901292 222 0.179
canonical wnt signaling pathway GO:0060070 130 0.175
regulation of mast cell proliferation GO:0070666 4 0.175
leukocyte activation involved in immune response GO:0002366 126 0.172
cellular response to peptide hormone stimulus GO:0071375 92 0.171
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.169
t cell activation GO:0042110 289 0.169
alpha beta t cell activation GO:0046631 91 0.168
regulation of hormone levels GO:0010817 211 0.168
odontogenesis GO:0042476 78 0.166
kit signaling pathway GO:0038109 3 0.165
spermatid development GO:0007286 108 0.165
nucleoside triphosphate catabolic process GO:0009143 205 0.162
transmission of nerve impulse GO:0019226 76 0.161
learning or memory GO:0007611 148 0.160
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001267 4 0.158
negative regulation of protein metabolic process GO:0051248 282 0.158
cellular divalent inorganic cation homeostasis GO:0072503 127 0.157
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.156
positive regulation of t cell differentiation GO:0045582 52 0.154
extrinsic apoptotic signaling pathway GO:0097191 126 0.153
positive regulation of cell development GO:0010720 237 0.152
lymphocyte mediated immunity GO:0002449 139 0.152
ketone body metabolic process GO:1902224 3 0.152
endomembrane system organization GO:0010256 147 0.151
b cell homeostasis GO:0001782 34 0.150
germ cell development GO:0007281 185 0.150
regulation of t cell differentiation GO:0045580 83 0.149
positive regulation of proteolysis GO:0045862 85 0.148
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.148
positive regulation of intracellular transport GO:0032388 70 0.146
purine nucleoside metabolic process GO:0042278 241 0.146
positive regulation of nucleoside metabolic process GO:0045979 91 0.145
antigen processing and presentation of lipid antigen via mhc class ib GO:0048003 3 0.143
cytotoxic t cell degranulation GO:0043316 2 0.142
nucleobase containing small molecule metabolic process GO:0055086 352 0.142
regulation of metal ion transport GO:0010959 106 0.142
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.142
short chain fatty acid metabolic process GO:0046459 6 0.141
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:0001844 4 0.139
embryonic placenta development GO:0001892 98 0.139
regulation of homeostatic process GO:0032844 182 0.138
skin development GO:0043588 220 0.138
purine ribonucleoside catabolic process GO:0046130 205 0.137
negative regulation of cellular amine metabolic process GO:0033239 1 0.136
t cell activation involved in immune response GO:0002286 43 0.136
positive regulation of endocytosis GO:0045807 42 0.135
regulation of leukocyte apoptotic process GO:2000106 56 0.132
regulation of protein kinase activity GO:0045859 232 0.131
regulation of nucleotide metabolic process GO:0006140 169 0.131
cell activation involved in immune response GO:0002263 126 0.131
establishment of synaptic vesicle localization GO:0097480 57 0.130
protein modification by small protein conjugation or removal GO:0070647 207 0.127
cellular ketone metabolic process GO:0042180 84 0.127
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.125
liposaccharide metabolic process GO:1903509 27 0.125
divalent inorganic cation transport GO:0072511 178 0.124
wnt signaling pathway GO:0016055 188 0.124
nitrogen compound transport GO:0071705 271 0.124
programmed necrotic cell death GO:0097300 28 0.124
mesenchyme development GO:0060485 152 0.124
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.122
activation of immune response GO:0002253 138 0.122
osteoclast differentiation GO:0030316 62 0.120
myeloid leukocyte activation GO:0002274 83 0.120
ribose phosphate metabolic process GO:0019693 291 0.120
positive t cell selection GO:0043368 23 0.119
exocytosis GO:0006887 121 0.119
endoplasmic reticulum localization GO:0051643 2 0.119
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.119
generation of precursor metabolites and energy GO:0006091 103 0.117
cellular response to insulin stimulus GO:0032869 78 0.117
response to heat GO:0009408 27 0.116
calcium ion homeostasis GO:0055074 127 0.116
negative regulation of intracellular signal transduction GO:1902532 167 0.115
glycolipid metabolic process GO:0006664 25 0.115
positive regulation of nucleotide catabolic process GO:0030813 88 0.115
activation of cysteine type endopeptidase activity GO:0097202 27 0.114
negative regulation of protein phosphorylation GO:0001933 126 0.114
small gtpase mediated signal transduction GO:0007264 97 0.113
muscle cell differentiation GO:0042692 261 0.113
carbohydrate metabolic process GO:0005975 230 0.112
regulation of phagocytosis GO:0050764 33 0.112
response to radiation GO:0009314 165 0.111
positive regulation of apoptotic process GO:0043065 217 0.111
hematopoietic progenitor cell differentiation GO:0002244 143 0.111
regulation of cellular response to oxidative stress GO:1900407 19 0.110
multicellular organism growth GO:0035264 161 0.109
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.109
macromolecule catabolic process GO:0009057 281 0.108
response to oxidative stress GO:0006979 123 0.108
cell type specific apoptotic process GO:0097285 268 0.107
defense response to virus GO:0051607 68 0.107
rhythmic process GO:0048511 174 0.106
cellular response to radiation GO:0071478 28 0.106
regulation of nucleotide catabolic process GO:0030811 122 0.106
phagocytosis GO:0006909 66 0.104
somatic cell dna recombination GO:0016444 51 0.104
regulation of neuron apoptotic process GO:0043523 122 0.104
positive regulation of mitochondrial membrane permeability GO:0035794 12 0.103
cellular carbohydrate metabolic process GO:0044262 119 0.103
protein processing GO:0016485 163 0.102
natural killer cell mediated cytotoxicity GO:0042267 29 0.100
Human
regulation of rho protein signal transduction GO:0035023 71 0.099
membrane lipid metabolic process GO:0006643 53 0.098
positive regulation of cellular amine metabolic process GO:0033240 5 0.097
positive regulation of protein modification process GO:0031401 299 0.097
natural killer cell activation GO:0030101 44 0.096
mast cell proliferation GO:0070662 4 0.096
regulation of cellular ketone metabolic process GO:0010565 66 0.096
cellular response to dna damage stimulus GO:0006974 207 0.095
protein catabolic process GO:0030163 221 0.095
mapk cascade GO:0000165 281 0.095
stem cell differentiation GO:0048863 268 0.094
actin filament based movement GO:0030048 23 0.094
lipid storage GO:0019915 36 0.094
interferon beta biosynthetic process GO:0045350 4 0.094
protein targeting to vacuole GO:0006623 3 0.093
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.093
organic acid biosynthetic process GO:0016053 86 0.092
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c GO:0008635 4 0.092
nuclear division GO:0000280 158 0.091
positive regulation of leukocyte differentiation GO:1902107 86 0.091
phospholipid metabolic process GO:0006644 87 0.091
regulation of protein serine threonine kinase activity GO:0071900 157 0.091
regulation of cysteine type endopeptidase activity GO:2000116 65 0.090
female sex differentiation GO:0046660 84 0.090
cellular protein catabolic process GO:0044257 155 0.089
calcium ion transport GO:0006816 159 0.089
regulation of gtp catabolic process GO:0033124 113 0.089
divalent inorganic cation homeostasis GO:0072507 138 0.089
epithelial tube morphogenesis GO:0060562 303 0.089
activation of membrane attack complex GO:0001905 4 0.087
stem cell development GO:0048864 219 0.087
thymus development GO:0048538 41 0.087
positive regulation of exocytosis GO:0045921 20 0.086
carbohydrate derivative biosynthetic process GO:1901137 183 0.086
positive regulation of melanocyte differentiation GO:0045636 5 0.086
leukocyte apoptotic process GO:0071887 71 0.086
regulation of rho gtpase activity GO:0032319 58 0.086
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.084
ras protein signal transduction GO:0007265 77 0.084
innate immune response GO:0045087 157 0.084
Human
negative regulation of homeostatic process GO:0032845 71 0.084
male sex differentiation GO:0046661 109 0.084
angiogenesis GO:0001525 201 0.084
developmental maturation GO:0021700 193 0.083
protein localization to organelle GO:0033365 185 0.083
spermatid differentiation GO:0048515 115 0.083
leukocyte mediated cytotoxicity GO:0001909 62 0.082
Human
establishment of protein localization to organelle GO:0072594 118 0.082
sensory organ morphogenesis GO:0090596 242 0.081
regulation of endopeptidase activity GO:0052548 89 0.081
regulation of chemotaxis GO:0050920 53 0.081
positive regulation of nucleotide metabolic process GO:0045981 114 0.080
regulation of protein localization GO:0032880 231 0.080
cell junction organization GO:0034330 77 0.080
positive regulation of protein phosphorylation GO:0001934 242 0.079
glycerolipid metabolic process GO:0046486 122 0.079
regulation of neuron death GO:1901214 134 0.079
cellular response to gamma radiation GO:0071480 4 0.079
regulation of natural killer cell activation GO:0032814 22 0.078
myeloid cell homeostasis GO:0002262 114 0.078
mast cell apoptotic process GO:0033024 5 0.077
renal system development GO:0072001 225 0.077
positive regulation of mapk cascade GO:0043410 170 0.077
tyrosine metabolic process GO:0006570 4 0.077
intracellular mrna localization GO:0008298 4 0.077
regulation of synaptic plasticity GO:0048167 87 0.076
establishment of protein localization to vacuole GO:0072666 4 0.076
negative regulation of phosphate metabolic process GO:0045936 184 0.076
negative regulation of protein modification process GO:0031400 163 0.075
single organismal cell cell adhesion GO:0016337 131 0.075
negative regulation of anoikis GO:2000811 2 0.074
wound healing GO:0042060 157 0.074
positive regulation of map kinase activity GO:0043406 84 0.074
tissue remodeling GO:0048771 102 0.074
lipid biosynthetic process GO:0008610 179 0.073
forebrain development GO:0030900 302 0.072
regionalization GO:0003002 337 0.072
negative regulation of lymphocyte activation GO:0051250 91 0.072
regulation of myeloid cell apoptotic process GO:0033032 19 0.071
neuron maturation GO:0042551 29 0.071
leukocyte mediated immunity GO:0002443 174 0.071
response to hydrogen peroxide GO:0042542 32 0.070
single organism cell adhesion GO:0098602 156 0.070
neuron projection extension GO:1990138 64 0.070
regulation of cellular amino acid metabolic process GO:0006521 5 0.070
regulation of peptidase activity GO:0052547 96 0.069
development of primary female sexual characteristics GO:0046545 73 0.069
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.068
gonad development GO:0008406 141 0.068
natural killer cell mediated immunity GO:0002228 29 0.068
Human
regulation of kinase activity GO:0043549 249 0.068
positive regulation of kinase activity GO:0033674 155 0.067
positive regulation of smooth muscle cell migration GO:0014911 4 0.067
protein localization to vacuole GO:0072665 4 0.067
myeloid cell apoptotic process GO:0033028 22 0.067
myeloid leukocyte migration GO:0097529 57 0.067
positive regulation of regulated secretory pathway GO:1903307 10 0.067
phosphatidylinositol metabolic process GO:0046488 45 0.066
multicellular organismal homeostasis GO:0048871 164 0.066
positive regulation of activation of membrane attack complex GO:0001970 2 0.066
kidney development GO:0001822 213 0.066
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.066
ear development GO:0043583 200 0.066
cell chemotaxis GO:0060326 81 0.065
negative regulation of cell development GO:0010721 169 0.065
positive regulation of neuroepithelial cell differentiation GO:1902913 5 0.065
fatty acid biosynthetic process GO:0006633 41 0.065
regulation of nitrogen utilization GO:0006808 2 0.065
regulation of transmembrane transport GO:0034762 128 0.065
response to light stimulus GO:0009416 135 0.064
anatomical structure homeostasis GO:0060249 145 0.064
sensory perception GO:0007600 245 0.063
cell adhesion GO:0007155 329 0.063
g protein coupled receptor signaling pathway GO:0007186 243 0.063
response to starvation GO:0042594 65 0.063
carboxylic acid biosynthetic process GO:0046394 86 0.062
cell substrate adhesion GO:0031589 130 0.062
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.062
retina development in camera type eye GO:0060041 119 0.062
developmental cell growth GO:0048588 84 0.061
regulation of receptor activity GO:0010469 41 0.061
apoptotic process involved in mammary gland involution GO:0060057 4 0.061
erk1 and erk2 cascade GO:0070371 77 0.061
body morphogenesis GO:0010171 45 0.061
positive regulation of transferase activity GO:0051347 167 0.061
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.061
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.061
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 3 0.061
negative regulation of myeloid cell apoptotic process GO:0033033 11 0.061
genetic imprinting GO:0071514 27 0.060
mitochondrion organization GO:0007005 134 0.060
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.060
immune response regulating signaling pathway GO:0002764 125 0.060
response to ethanol GO:0045471 18 0.060
regulation of myeloid cell differentiation GO:0045637 96 0.060
visual perception GO:0007601 52 0.059
negative regulation of phosphorylation GO:0042326 166 0.059
cellular response to growth factor stimulus GO:0071363 197 0.058
positive regulation of release of cytochrome c from mitochondria GO:0090200 5 0.058
cellular response to oxidative stress GO:0034599 76 0.058
cell division GO:0051301 120 0.058
regulation of mitochondrion organization GO:0010821 27 0.058
regulation of osteoclast differentiation GO:0045670 36 0.056
regulation of epithelial cell proliferation GO:0050678 141 0.056
zymogen activation GO:0031638 41 0.056
positive regulation of endopeptidase activity GO:0010950 43 0.056
positive regulation of protein complex assembly GO:0031334 45 0.056
regulation of purine nucleotide catabolic process GO:0033121 122 0.056
chemotaxis GO:0006935 247 0.055
eye pigmentation GO:0048069 3 0.055
t cell homeostasis GO:0043029 35 0.055
positive regulation of natural killer cell activation GO:0032816 15 0.055
response to organic cyclic compound GO:0014070 198 0.055
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.055
posttranscriptional regulation of gene expression GO:0010608 155 0.055
ectopic germ cell programmed cell death GO:0035234 9 0.055
response to insulin GO:0032868 100 0.055
membrane fusion GO:0061025 38 0.054
skeletal system development GO:0001501 356 0.054
mesenchymal cell differentiation GO:0048762 107 0.054
muscle system process GO:0003012 141 0.054
positive regulation of cell killing GO:0031343 33 0.054
glycerophospholipid metabolic process GO:0006650 71 0.053
t cell selection GO:0045058 34 0.053
post embryonic organ development GO:0048569 17 0.053
regulation of ph GO:0006885 26 0.053
cellular component assembly involved in morphogenesis GO:0010927 139 0.053
negative regulation of cellular component organization GO:0051129 194 0.053
positive regulation of cellular protein catabolic process GO:1903364 34 0.053
thymocyte apoptotic process GO:0070242 19 0.052
positive regulation of cell motility GO:2000147 116 0.052
cell matrix adhesion GO:0007160 68 0.052

Lyst disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system cancer DOID:0060083 0 0.663
hematologic cancer DOID:2531 0 0.663
cancer DOID:162 0 0.663
disease of cellular proliferation DOID:14566 0 0.663
organ system cancer DOID:0050686 0 0.663
immune system disease DOID:2914 0 0.403
disease of anatomical entity DOID:7 0 0.403
gastrointestinal system cancer DOID:3119 0 0.096
nervous system disease DOID:863 0 0.070
lymphatic system disease DOID:75 0 0.061
central nervous system disease DOID:331 0 0.058
neurodegenerative disease DOID:1289 0 0.058
disease of metabolism DOID:0014667 0 0.052
inherited metabolic disorder DOID:655 0 0.052