Mus musculus

199 known processes

Macf1

microtubule-actin crosslinking factor 1

(Aliases: Acf7,ABP620,mACF7,Aclp7,mKIAA0465,MACF,R74989)

Macf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.988
Fly
microtubule nucleation GO:0007020 2 0.936
regulation of microtubule based process GO:0032886 52 0.913
negative regulation of protein depolymerization GO:1901880 21 0.882
Fly
microtubule based process GO:0007017 236 0.865
negative regulation of protein complex disassembly GO:0043242 22 0.856
Fly
microtubule cytoskeleton organization GO:0000226 157 0.851
Mouse Fly
organelle localization GO:0051640 179 0.832
regulation of microtubule cytoskeleton organization GO:0070507 37 0.822
Mouse Fly
regulation of cytoskeleton organization GO:0051493 122 0.805
Mouse Fly
establishment of spindle localization GO:0051293 19 0.774
protein depolymerization GO:0051261 34 0.768
Fly
establishment of organelle localization GO:0051656 122 0.757
spindle localization GO:0051653 22 0.755
axonogenesis GO:0007409 274 0.683
Mouse Fly
microtubule depolymerization GO:0007019 15 0.670
Fly
negative regulation of cellular component organization GO:0051129 194 0.627
Fly
regulation of protein depolymerization GO:1901879 26 0.614
Fly
establishment or maintenance of cell polarity GO:0007163 86 0.607
microtubule polymerization GO:0046785 12 0.597
microtubule polymerization or depolymerization GO:0031109 26 0.586
Mouse Fly
axon guidance GO:0007411 141 0.485
Fly
regulation of organelle organization GO:0033043 289 0.444
Mouse Fly
negative regulation of organelle organization GO:0010639 90 0.426
Fly
cellular protein complex assembly GO:0043623 116 0.415
small gtpase mediated signal transduction GO:0007264 97 0.384
maintenance of location GO:0051235 89 0.374
cell division GO:0051301 120 0.355
protein polymerization GO:0051258 57 0.301
organelle assembly GO:0070925 177 0.296
organelle fission GO:0048285 170 0.292
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.290
Mouse Fly
cellular protein complex disassembly GO:0043624 36 0.263
Fly
regulation of microtubule depolymerization GO:0031114 13 0.246
Fly
regulation of neuron projection development GO:0010975 169 0.244
Fly
nuclear division GO:0000280 158 0.236
body morphogenesis GO:0010171 45 0.225
regulation of protein complex disassembly GO:0043244 28 0.214
Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.210
chemotaxis GO:0006935 247 0.210
Fly
negative regulation of synapse assembly GO:0051964 3 0.208
microtubule organizing center organization GO:0031023 28 0.207
mitotic nuclear division GO:0007067 48 0.204
stem cell maintenance GO:0019827 130 0.203
cellular ketone metabolic process GO:0042180 84 0.199
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.190
Fly
maintenance of protein location in cell GO:0032507 20 0.186
regulation of cellular component biogenesis GO:0044087 181 0.181
protein complex disassembly GO:0043241 40 0.179
Fly
microtubule based movement GO:0007018 84 0.178
Mouse
dendrite development GO:0016358 115 0.171
Fly
amine metabolic process GO:0009308 45 0.169
maintenance of location in cell GO:0051651 24 0.165
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.164
protein localization to membrane GO:0072657 108 0.161
macromolecular complex disassembly GO:0032984 43 0.160
Fly
ras protein signal transduction GO:0007265 77 0.148
peptidyl serine phosphorylation GO:0018105 74 0.146
germ cell development GO:0007281 185 0.140
histone h4 k16 acetylation GO:0043984 3 0.136
regulation of ras protein signal transduction GO:0046578 114 0.128
establishment of spindle orientation GO:0051294 15 0.128
synapse organization GO:0050808 125 0.123
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.121
oocyte differentiation GO:0009994 35 0.117
negative regulation of phosphorylation GO:0042326 166 0.114
carbohydrate metabolic process GO:0005975 230 0.113
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.111
mitotic cell cycle process GO:1903047 159 0.107
neuron projection guidance GO:0097485 141 0.107
Fly
epithalamus development GO:0021538 2 0.106
negative regulation of protein metabolic process GO:0051248 282 0.105
regulation of cell substrate adhesion GO:0010810 73 0.105
cofactor metabolic process GO:0051186 80 0.104
adult behavior GO:0030534 135 0.102
inorganic cation transmembrane transport GO:0098662 207 0.102
microtubule anchoring GO:0034453 9 0.100
digestive system development GO:0055123 200 0.095
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.095
stem cell development GO:0048864 219 0.092
transmission of nerve impulse GO:0019226 76 0.092
regulation of jnk cascade GO:0046328 62 0.089
regulation of cellular ketone metabolic process GO:0010565 66 0.088
regulation of cell projection organization GO:0031344 206 0.087
Fly
peptidyl serine modification GO:0018209 83 0.087
sensory perception GO:0007600 245 0.086
regulation of response to drug GO:2001023 2 0.086
ribonucleotide catabolic process GO:0009261 208 0.085
cellular amino acid metabolic process GO:0006520 103 0.083
mitotic cytokinesis GO:0000281 4 0.081
mrna metabolic process GO:0016071 84 0.080
synaptic transmission GO:0007268 329 0.079
negative regulation of phosphate metabolic process GO:0045936 184 0.078
positive regulation of ras gtpase activity GO:0032320 65 0.078
ribonucleoside triphosphate metabolic process GO:0009199 220 0.078
cell recognition GO:0008037 83 0.077
Fly
positive regulation of binding GO:0051099 49 0.077
positive regulation of protein binding GO:0032092 29 0.074
regulation of cellular component size GO:0032535 121 0.073
Fly
sensory perception of mechanical stimulus GO:0050954 107 0.073
nucleoside phosphate catabolic process GO:1901292 222 0.072
regulation of protein binding GO:0043393 60 0.070
mitotic cell cycle GO:0000278 195 0.070
regulation of spindle organization GO:0090224 2 0.068
regulation of purine nucleotide metabolic process GO:1900542 169 0.068
cytoskeleton dependent intracellular transport GO:0030705 50 0.068
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.067
forebrain development GO:0030900 302 0.067
positive regulation of gtp catabolic process GO:0033126 85 0.067
positive regulation of kinase activity GO:0033674 155 0.067
learning or memory GO:0007611 148 0.066
cellular amine metabolic process GO:0044106 44 0.066
ribonucleoside triphosphate catabolic process GO:0009203 199 0.065
positive regulation of cell development GO:0010720 237 0.064
Fly
cytoplasmic microtubule organization GO:0031122 14 0.064
Mouse
adult locomotory behavior GO:0008344 91 0.064
establishment of protein localization to membrane GO:0090150 54 0.063
regulation of cellular amine metabolic process GO:0033238 20 0.063
ribonucleotide metabolic process GO:0009259 291 0.062
microtubule based transport GO:0010970 50 0.062
Mouse
cell matrix adhesion GO:0007160 68 0.062
multicellular organism growth GO:0035264 161 0.061
oocyte construction GO:0007308 2 0.060
regulation of gtp catabolic process GO:0033124 113 0.058
negative regulation of cell development GO:0010721 169 0.058
histone methylation GO:0016571 71 0.057
aromatic compound catabolic process GO:0019439 286 0.057
extrinsic apoptotic signaling pathway GO:0097191 126 0.057
posttranscriptional regulation of gene expression GO:0010608 155 0.056
sensory perception of sound GO:0007605 97 0.056
histone lysine methylation GO:0034968 50 0.056
negative regulation of intracellular signal transduction GO:1902532 167 0.056
circadian rhythm GO:0007623 114 0.055
gene silencing by rna GO:0031047 19 0.055
regulation of histone methylation GO:0031060 30 0.053
peptidyl lysine methylation GO:0018022 29 0.053
regulation of protein localization GO:0032880 231 0.053
actin cytoskeleton reorganization GO:0031532 21 0.052
glycosyl compound catabolic process GO:1901658 206 0.052
cytokinesis GO:0000910 17 0.052
gastrulation GO:0007369 116 0.052
nucleoside metabolic process GO:0009116 246 0.051
female gamete generation GO:0007292 74 0.050
histone h3 k4 trimethylation GO:0080182 5 0.050
nucleoside catabolic process GO:0009164 206 0.050
regulation of peptidyl serine phosphorylation GO:0033135 39 0.050
histone h4 acetylation GO:0043967 10 0.050
protein localization to plasma membrane GO:0072659 57 0.050
Human
spindle organization GO:0007051 28 0.049
establishment of mitotic spindle localization GO:0040001 12 0.049
regulation of cellular catabolic process GO:0031329 242 0.049
regulation of transferase activity GO:0051338 263 0.049
regulation of kinase activity GO:0043549 249 0.048
regulation of hydrolase activity GO:0051336 246 0.047
ribonucleoside metabolic process GO:0009119 245 0.047
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.047
male gamete generation GO:0048232 285 0.047
neuron projection extension GO:1990138 64 0.046
Fly
adherens junction assembly GO:0034333 22 0.046
cardiac conduction GO:0061337 17 0.046
response to organonitrogen compound GO:0010243 246 0.045
glycosyl compound metabolic process GO:1901657 246 0.045
intracellular protein transport GO:0006886 204 0.045
locomotory behavior GO:0007626 195 0.044
oogenesis GO:0048477 56 0.043
macromolecule catabolic process GO:0009057 281 0.043
regulation of neuron differentiation GO:0045664 281 0.043
Fly
rho protein signal transduction GO:0007266 32 0.043
porphyrin containing compound metabolic process GO:0006778 22 0.042
purine nucleotide metabolic process GO:0006163 302 0.042
cell maturation GO:0048469 127 0.042
regulation of nucleotide metabolic process GO:0006140 169 0.041
protein methylation GO:0006479 81 0.041
organic cyclic compound catabolic process GO:1901361 295 0.041
synapse assembly GO:0007416 56 0.041
regulation of cell cycle GO:0051726 281 0.041
habenula development GO:0021986 2 0.040
gene silencing by mirna GO:0035195 10 0.040
guanosine containing compound catabolic process GO:1901069 144 0.040
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.040
gonad morphogenesis GO:0035262 1 0.040
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.040
regulation of nucleoside metabolic process GO:0009118 130 0.040
epithelial cell development GO:0002064 159 0.040
jak stat cascade GO:0007259 42 0.040
protein localization to organelle GO:0033365 185 0.040
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
cognition GO:0050890 149 0.039
muscle cell differentiation GO:0042692 261 0.039
peptidyl threonine modification GO:0018210 31 0.038
macromolecule methylation GO:0043414 120 0.038
purine ribonucleotide metabolic process GO:0009150 290 0.038
purine nucleoside metabolic process GO:0042278 241 0.038
regulation of anatomical structure size GO:0090066 178 0.038
Fly
ribose phosphate metabolic process GO:0019693 291 0.038
ribonucleoside catabolic process GO:0042454 206 0.037
positive regulation of neuron projection development GO:0010976 79 0.036
Fly
membrane organization GO:0061024 245 0.036
actin cytoskeleton organization GO:0030036 220 0.036
purine ribonucleoside catabolic process GO:0046130 205 0.036
cellular carbohydrate metabolic process GO:0044262 119 0.036
regulation of nuclear division GO:0051783 56 0.036
compound eye development GO:0048749 1 0.036
ribonucleoprotein complex subunit organization GO:0071826 28 0.036
formation of primary germ layer GO:0001704 77 0.036
heterocycle catabolic process GO:0046700 280 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
histone h3 k4 methylation GO:0051568 23 0.035
positive regulation of rho gtpase activity GO:0032321 41 0.035
protein polyubiquitination GO:0000209 33 0.035
neuron neuron synaptic transmission GO:0007270 69 0.035
regulation of histone modification GO:0031056 56 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.034
tetrapyrrole metabolic process GO:0033013 22 0.034
purine nucleoside catabolic process GO:0006152 205 0.034
tube closure GO:0060606 91 0.034
memory GO:0007613 58 0.034
maintenance of chromatin silencing GO:0006344 2 0.034
ear development GO:0043583 200 0.034
regulation of mapk cascade GO:0043408 248 0.033
divalent inorganic cation transport GO:0072511 178 0.033
developmental maturation GO:0021700 193 0.033
muscle tissue development GO:0060537 308 0.032
neuroblast fate commitment GO:0014017 1 0.032
cation transmembrane transport GO:0098655 266 0.032
protein targeting to membrane GO:0006612 20 0.032
chromosome segregation GO:0007059 48 0.032
chromatin modification GO:0016568 187 0.031
actin filament based movement GO:0030048 23 0.031
mesenchyme development GO:0060485 152 0.031
calcium ion transmembrane transport GO:0070588 85 0.031
regulation of rho protein signal transduction GO:0035023 71 0.031
purine containing compound metabolic process GO:0072521 311 0.031
dna metabolic process GO:0006259 303 0.030
protein alkylation GO:0008213 81 0.030
plasma membrane organization GO:0007009 90 0.030
Human
chromatin organization GO:0006325 206 0.030
inorganic ion transmembrane transport GO:0098660 234 0.029
mitochondrion distribution GO:0048311 4 0.029
gonad development GO:0008406 141 0.029
peptidyl amino acid modification GO:0018193 336 0.029
regulation of intracellular transport GO:0032386 159 0.029
sensory organ morphogenesis GO:0090596 242 0.029
regulation of nucleotide catabolic process GO:0030811 122 0.029
neural tube closure GO:0001843 90 0.029
axon cargo transport GO:0008088 33 0.029
Mouse
regionalization GO:0003002 337 0.029
sequestering of calcium ion GO:0051208 18 0.029
regulation of protein kinase activity GO:0045859 232 0.028
methylation GO:0032259 134 0.028
rna interference GO:0016246 2 0.028
positive regulation of chromatin modification GO:1903310 28 0.028
leukocyte differentiation GO:0002521 342 0.028
covalent chromatin modification GO:0016569 163 0.028
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.028
regulation of cell cycle process GO:0010564 160 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.027
regulation of purine nucleotide catabolic process GO:0033121 122 0.027
norepinephrine transport GO:0015874 2 0.027
positive regulation of protein modification process GO:0031401 299 0.027
regulation of binding GO:0051098 111 0.026
negative regulation of nervous system development GO:0051961 156 0.026
positive regulation of neuron differentiation GO:0045666 141 0.026
Fly
positive regulation of protein phosphorylation GO:0001934 242 0.026
establishment of vesicle localization GO:0051650 81 0.026
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.026
divalent metal ion transport GO:0070838 172 0.026
regulation of extent of cell growth GO:0061387 52 0.026
Fly
morphogenesis of embryonic epithelium GO:0016331 159 0.026
mitotic sister chromatid segregation GO:0000070 14 0.026
positive regulation of protein kinase activity GO:0045860 144 0.025
negative regulation of cellular amine metabolic process GO:0033239 1 0.025
cellular ion homeostasis GO:0006873 165 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
embryonic body morphogenesis GO:0010172 10 0.025
primary neural tube formation GO:0014020 95 0.025
cofactor biosynthetic process GO:0051188 41 0.025
establishment of meiotic spindle orientation GO:0051296 1 0.025
nucleotide metabolic process GO:0009117 332 0.025
negative regulation of microtubule depolymerization GO:0007026 13 0.025
Fly
regulation of lymphocyte activation GO:0051249 240 0.025
multi multicellular organism process GO:0044706 109 0.025
regulation of chromosome organization GO:0033044 83 0.024
embryonic organ morphogenesis GO:0048562 276 0.024
negative regulation of protein modification process GO:0031400 163 0.024
action potential GO:0001508 78 0.024
spindle assembly GO:0051225 13 0.024
central nervous system projection neuron axonogenesis GO:0021952 21 0.024
regulation of ion homeostasis GO:2000021 64 0.024
regulation of ryanodine sensitive calcium release channel activity GO:0060314 10 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
Mouse
sequestering of metal ion GO:0051238 19 0.024
regulation of chromatin organization GO:1902275 57 0.024
oxidation reduction process GO:0055114 342 0.023
regulation of mitotic spindle organization GO:0060236 2 0.023
transcription from rna polymerase iii promoter GO:0006383 3 0.023
centrosome organization GO:0051297 26 0.023
rhythmic process GO:0048511 174 0.023
cellular response to organonitrogen compound GO:0071417 145 0.023
t cell proliferation GO:0042098 120 0.023
purine containing compound catabolic process GO:0072523 213 0.022
mitotic spindle organization GO:0007052 10 0.022
peptidyl tyrosine phosphorylation GO:0018108 143 0.022
multi organism behavior GO:0051705 62 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
peripheral nervous system neuron axonogenesis GO:0048936 3 0.022
negative regulation of mapk cascade GO:0043409 65 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.021
response to peptide hormone GO:0043434 127 0.021
posttranscriptional gene silencing by rna GO:0035194 10 0.021
synaptic vesicle localization GO:0097479 59 0.021
anatomical structure homeostasis GO:0060249 145 0.021
positive regulation of nucleoside metabolic process GO:0045979 91 0.021
terminal button organization GO:0072553 3 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
meiotic nuclear division GO:0007126 115 0.021
cellular divalent inorganic cation homeostasis GO:0072503 127 0.021
neuron migration GO:0001764 122 0.021
attachment of spindle microtubules to kinetochore GO:0008608 4 0.021
central nervous system neuron axonogenesis GO:0021955 28 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
regulation of ion transport GO:0043269 215 0.021
negative regulation of cytoskeleton organization GO:0051494 36 0.021
Fly
rac protein signal transduction GO:0016601 13 0.021
circulatory system process GO:0003013 197 0.021
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.020
ion transmembrane transport GO:0034220 361 0.020
apoptotic signaling pathway GO:0097190 306 0.020
muscle cell development GO:0055001 133 0.020
neuron recognition GO:0008038 25 0.020
Fly
second messenger mediated signaling GO:0019932 73 0.020
camera type eye development GO:0043010 266 0.020
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
endoderm development GO:0007492 45 0.020
nucleoside monophosphate metabolic process GO:0009123 85 0.020
spermatogenesis GO:0007283 284 0.020
positive regulation of cell activation GO:0050867 158 0.020
porphyrin containing compound biosynthetic process GO:0006779 16 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.020
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.019
negative regulation of intracellular protein transport GO:0090317 27 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
tetrapyrrole biosynthetic process GO:0033014 16 0.019
guanosine containing compound metabolic process GO:1901068 144 0.019
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
regulation of cell activation GO:0050865 289 0.019
kidney development GO:0001822 213 0.019
positive regulation of cell substrate adhesion GO:0010811 47 0.019
endocytosis GO:0006897 168 0.019
cell growth GO:0016049 130 0.019
Fly
development of primary sexual characteristics GO:0045137 143 0.019
cellular homeostasis GO:0019725 240 0.019
neuromuscular process GO:0050905 99 0.019
centrosome separation GO:0051299 4 0.019
cell migration involved in gastrulation GO:0042074 13 0.019
posttranscriptional gene silencing GO:0016441 10 0.019
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.019
developmental cell growth GO:0048588 84 0.019
Fly
glucan metabolic process GO:0044042 32 0.019
multi organism reproductive behavior GO:0044705 29 0.019
nucleus localization GO:0051647 20 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
positive regulation of organelle organization GO:0010638 128 0.018
cell adhesion GO:0007155 329 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
somitogenesis GO:0001756 69 0.018
heart contraction GO:0060047 93 0.018
mitotic sister chromatid cohesion GO:0007064 1 0.018
regulation of lymphocyte proliferation GO:0050670 117 0.018
wound healing GO:0042060 157 0.018
striated muscle contraction GO:0006941 45 0.018
mapk cascade GO:0000165 281 0.018
negative regulation of protein targeting to membrane GO:0090315 1 0.018
sodium ion transmembrane transport GO:0035725 49 0.018
regulation of response to wounding GO:1903034 189 0.018
response to acid chemical GO:0001101 111 0.018
calcium mediated signaling GO:0019722 46 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
protein homotrimerization GO:0070207 4 0.018
dna recombination GO:0006310 92 0.017
protein ubiquitination GO:0016567 171 0.017
neural tube development GO:0021915 160 0.017
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.017
secondary metabolic process GO:0019748 18 0.017
mitotic centrosome separation GO:0007100 4 0.017
hindbrain morphogenesis GO:0021575 46 0.017
tube formation GO:0035148 140 0.017
Fly
establishment of synaptic vesicle localization GO:0097480 57 0.017
actin filament organization GO:0007015 113 0.017
extracellular structure organization GO:0043062 148 0.017
t cell activation GO:0042110 289 0.017
regulation of membrane potential GO:0042391 192 0.017
positive regulation of cell adhesion GO:0045785 80 0.017
adherens junction organization GO:0034332 28 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
nuclear transport GO:0051169 139 0.017
cellularization GO:0007349 1 0.017
peptidyl tyrosine modification GO:0018212 145 0.017
exit from mitosis GO:0010458 3 0.017
positive regulation of potassium ion transport GO:0043268 3 0.016
cellular response to acidic ph GO:0071468 4 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
Fly
organophosphate catabolic process GO:0046434 232 0.016
golgi vesicle transport GO:0048193 30 0.016
Human
negative regulation of protein phosphorylation GO:0001933 126 0.016
cell cell recognition GO:0009988 44 0.016
positive regulation of leukocyte differentiation GO:1902107 86 0.016
cation transport GO:0006812 399 0.016
homeostasis of number of cells GO:0048872 210 0.016
regulation of cell adhesion GO:0030155 154 0.016
regulation of homeostatic process GO:0032844 182 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
i kappab kinase nf kappab signaling GO:0007249 85 0.016
regulation of metal ion transport GO:0010959 106 0.015
glucose homeostasis GO:0042593 128 0.015
carbohydrate catabolic process GO:0016052 32 0.015
oocyte axis specification GO:0007309 2 0.015
regulation of ras gtpase activity GO:0032318 88 0.015
peptidyl lysine modification GO:0018205 77 0.015
central nervous system neuron differentiation GO:0021953 162 0.015
regulation of cell motility GO:2000145 236 0.015
sister chromatid segregation GO:0000819 20 0.015
establishment of protein localization to plasma membrane GO:0090002 34 0.015
Human
actin mediated cell contraction GO:0070252 15 0.015
regulation of circadian rhythm GO:0042752 58 0.015
transmembrane transport GO:0055085 412 0.015
establishment of planar polarity GO:0001736 28 0.015
ensheathment of neurons GO:0007272 76 0.015
positive regulation of chromosome organization GO:2001252 33 0.015
regulation of cell size GO:0008361 72 0.015
Fly
immunoglobulin production GO:0002377 73 0.015
establishment of tissue polarity GO:0007164 28 0.015
response to extracellular stimulus GO:0009991 127 0.015
regulation of cell migration GO:0030334 219 0.015
cranial nerve development GO:0021545 41 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
skeletal system development GO:0001501 356 0.015
cell junction assembly GO:0034329 52 0.015
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 9 0.015
regulation of cell division GO:0051302 76 0.014
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.014
peptidyl threonine phosphorylation GO:0018107 31 0.014
positive regulation of gtpase activity GO:0043547 85 0.014
positive regulation of leukocyte proliferation GO:0070665 73 0.014
single fertilization GO:0007338 82 0.014
positive regulation of nervous system development GO:0051962 221 0.014
Fly
regulation of establishment of protein localization GO:0070201 181 0.014
retina development in camera type eye GO:0060041 119 0.014
response to nutrient levels GO:0031667 109 0.014
negative regulation of cell growth involved in cardiac muscle cell development GO:0061052 2 0.014
ventricular cardiac myofibril assembly GO:0055005 3 0.014
exocytosis GO:0006887 121 0.014
protein targeting to plasma membrane GO:0072661 7 0.014
regulation of organ morphogenesis GO:2000027 144 0.014
nephron epithelium development GO:0072009 92 0.014
astral microtubule organization GO:0030953 3 0.014
striated muscle tissue development GO:0014706 293 0.014
regulation of jak stat cascade GO:0046425 34 0.014
negative regulation of heart rate GO:0010459 4 0.014
heart process GO:0003015 94 0.014
hindbrain development GO:0030902 128 0.014
cell cell junction organization GO:0045216 72 0.013
positive regulation of chromosome segregation GO:0051984 4 0.013
reproductive behavior GO:0019098 32 0.013
cell substrate adhesion GO:0031589 130 0.013
cellular response to acid chemical GO:0071229 68 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
axon ensheathment GO:0008366 76 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
cell differentiation in hindbrain GO:0021533 24 0.013
regulation of leukocyte proliferation GO:0070663 121 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
glucose metabolic process GO:0006006 92 0.013
ear morphogenesis GO:0042471 118 0.013
blood circulation GO:0008015 195 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
regulation of system process GO:0044057 200 0.013

Macf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.064
nervous system disease DOID:863 0 0.064
central nervous system disease DOID:331 0 0.027
musculoskeletal system disease DOID:17 0 0.021
connective tissue disease DOID:65 0 0.021
bone development disease DOID:0080006 0 0.020
bone disease DOID:0080001 0 0.020
neuromuscular disease DOID:440 0 0.018
charcot marie tooth disease DOID:10595 0 0.018
neuropathy DOID:870 0 0.018
epilepsy syndrome DOID:1826 0 0.017
brain disease DOID:936 0 0.017
electroclinical syndrome DOID:0050701 0 0.017