Mus musculus

151 known processes

Mael

maelstrom homolog (Drosophila)

(Aliases: AU019877,4933405K18Rik)

Mael biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna methylation involved in gamete generation GO:0043046 15 0.958
pirna metabolic process GO:0034587 12 0.955
pole plasm assembly GO:0007315 2 0.408
Fly
gene silencing by rna GO:0031047 19 0.362
male meiosis GO:0007140 37 0.289
dna metabolic process GO:0006259 303 0.286
oocyte construction GO:0007308 2 0.278
Fly
oocyte axis specification GO:0007309 2 0.252
Fly
gene silencing GO:0016458 38 0.233
meiosis i GO:0007127 60 0.221
oocyte anterior posterior axis specification GO:0007314 2 0.215
Fly
meiotic cell cycle process GO:1903046 77 0.206
mitotic chromosome condensation GO:0007076 1 0.172
spermatogenesis GO:0007283 284 0.171
positive regulation of meiosis i GO:0060903 5 0.155
maternal determination of anterior posterior axis embryo GO:0008358 2 0.122
Fly
male gamete generation GO:0048232 285 0.121
spermatid differentiation GO:0048515 115 0.120
meiotic cell cycle GO:0051321 122 0.117
macromolecule methylation GO:0043414 120 0.116
intracellular mrna localization GO:0008298 4 0.116
Fly
nuclear division GO:0000280 158 0.114
dna modification GO:0006304 50 0.110
posttranscriptional gene silencing GO:0016441 10 0.105
Fly
posttranscriptional regulation of gene expression GO:0010608 155 0.103
Fly
rna 3 end processing GO:0031123 20 0.094
chromosome organization involved in meiosis GO:0070192 39 0.082
negative regulation of transposition GO:0010529 2 0.082
Fly
spermatid development GO:0007286 108 0.077
mrna 3 end processing GO:0031124 16 0.076
germ cell development GO:0007281 185 0.075
Fly
rna interference GO:0016246 2 0.074
methylation GO:0032259 134 0.071
meiotic nuclear division GO:0007126 115 0.069
organelle fission GO:0048285 170 0.069
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.069
oocyte differentiation GO:0009994 35 0.068
Fly
rna localization GO:0006403 23 0.065
Fly
male meiosis i GO:0007141 16 0.063
regulation of transposition GO:0010528 2 0.062
Fly
segmentation GO:0035282 93 0.062
Fly
asymmetric stem cell division GO:0098722 3 0.059
cellular macromolecule catabolic process GO:0044265 206 0.058
heterocycle catabolic process GO:0046700 280 0.056
translation GO:0006412 93 0.054
dna alkylation GO:0006305 43 0.053
aromatic compound catabolic process GO:0019439 286 0.053
cellular nitrogen compound catabolic process GO:0044270 280 0.052
posttranscriptional gene silencing by rna GO:0035194 10 0.051
Fly
macromolecule catabolic process GO:0009057 281 0.050
regulation of cellular catabolic process GO:0031329 242 0.047
nucleoside phosphate metabolic process GO:0006753 338 0.047
regulation of translation GO:0006417 71 0.046
dna methylation GO:0006306 43 0.046
nucleobase containing small molecule metabolic process GO:0055086 352 0.045
regulation of transcription by chromatin organization GO:0034401 0 0.045
organic cyclic compound catabolic process GO:1901361 295 0.044
chromosome segregation GO:0007059 48 0.044
cellularization GO:0007349 1 0.044
purine containing compound metabolic process GO:0072521 311 0.044
mitotic cell cycle GO:0000278 195 0.041
ribose phosphate metabolic process GO:0019693 291 0.040
oocyte development GO:0048599 33 0.039
Fly
regulation of cell cycle process GO:0010564 160 0.039
germ line stem cell division GO:0042078 2 0.039
regulation of cell cycle GO:0051726 281 0.039
dna recombination GO:0006310 92 0.038
chromatin organization GO:0006325 206 0.038
fertilization GO:0009566 127 0.036
ribonucleoside triphosphate metabolic process GO:0009199 220 0.036
heterochromatin organization GO:0070828 4 0.036
dna packaging GO:0006323 30 0.035
regionalization GO:0003002 337 0.035
Fly
rna catabolic process GO:0006401 29 0.035
female gamete generation GO:0007292 74 0.034
Fly
regulation of multi organism process GO:0043900 111 0.034
Fly
stem cell differentiation GO:0048863 268 0.034
Fly
regulation of cell division GO:0051302 76 0.034
regulation of organelle organization GO:0033043 289 0.033
sister chromatid segregation GO:0000819 20 0.033
purine nucleoside triphosphate metabolic process GO:0009144 226 0.033
positive regulation of organelle organization GO:0010638 128 0.033
purine nucleotide metabolic process GO:0006163 302 0.031
cell division GO:0051301 120 0.031
positive regulation of cellular catabolic process GO:0031331 148 0.031
cell maturation GO:0048469 127 0.030
Fly
mitotic cell cycle process GO:1903047 159 0.030
nucleoside metabolic process GO:0009116 246 0.030
ribonucleotide metabolic process GO:0009259 291 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
regulation of meiotic cell cycle GO:0051445 34 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.029
ribonucleoside metabolic process GO:0009119 245 0.028
protein modification by small protein conjugation or removal GO:0070647 207 0.028
axonogenesis GO:0007409 274 0.027
mitotic sister chromatid segregation GO:0000070 14 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.027
dna conformation change GO:0071103 37 0.027
oxidation reduction process GO:0055114 342 0.026
mrna processing GO:0006397 63 0.026
regulation of cellular ketone metabolic process GO:0010565 66 0.026
cellular ketone metabolic process GO:0042180 84 0.026
amine metabolic process GO:0009308 45 0.026
mrna catabolic process GO:0006402 22 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.026
regulation of defense response GO:0031347 233 0.025
developmental maturation GO:0021700 193 0.025
Fly
regulation of proteolysis GO:0030162 164 0.025
purine containing compound catabolic process GO:0072523 213 0.024
purine ribonucleotide metabolic process GO:0009150 290 0.024
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.024
negative regulation of phosphate metabolic process GO:0045936 184 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
protein catabolic process GO:0030163 221 0.023
negative regulation of nik nf kappab signaling GO:1901223 2 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
protein modification by small protein conjugation GO:0032446 187 0.023
cellular protein complex assembly GO:0043623 116 0.023
rna processing GO:0006396 105 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
apoptotic signaling pathway GO:0097190 306 0.022
regulation of cellular amino acid metabolic process GO:0006521 5 0.022
cellular lipid metabolic process GO:0044255 323 0.022
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 12 0.022
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 5 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.022
mitotic nuclear division GO:0007067 48 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
Fly
ribonucleotide catabolic process GO:0009261 208 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
regulation of cellular amine metabolic process GO:0033238 20 0.021
rho protein signal transduction GO:0007266 32 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
cellular amino acid metabolic process GO:0006520 103 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
nitrogen compound transport GO:0071705 271 0.020
male germ line stem cell asymmetric division GO:0048133 2 0.020
lipid biosynthetic process GO:0008610 179 0.020
ribonucleoprotein complex subunit organization GO:0071826 28 0.020
rna 5 end processing GO:0000966 1 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
protein ubiquitination GO:0016567 171 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
positive regulation of meiosis GO:0045836 14 0.019
stem cell maintenance GO:0019827 130 0.019
Fly
organonitrogen compound catabolic process GO:1901565 264 0.019
regulation of neuron projection development GO:0010975 169 0.019
oocyte maturation GO:0001556 18 0.019
cellular protein catabolic process GO:0044257 155 0.019
response to organic cyclic compound GO:0014070 198 0.019
synapsis GO:0007129 34 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
oogenesis GO:0048477 56 0.018
Fly
anterior posterior axis specification embryo GO:0008595 9 0.018
Fly
regulation of nuclear division GO:0051783 56 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
cellular amine metabolic process GO:0044106 44 0.018
ras protein signal transduction GO:0007265 77 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
protein maturation GO:0051604 176 0.018
regulation of cell projection organization GO:0031344 206 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
regulation of hydrolase activity GO:0051336 246 0.018
nucleoside catabolic process GO:0009164 206 0.018
mrna metabolic process GO:0016071 84 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
purine nucleoside monophosphate metabolic process GO:0009126 81 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
nucleotide metabolic process GO:0009117 332 0.017
negative regulation of cell cycle GO:0045786 123 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.017
ion transmembrane transport GO:0034220 361 0.017
cell type specific apoptotic process GO:0097285 268 0.017
nucleotide catabolic process GO:0009166 217 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
positive regulation of meiotic cell cycle GO:0051446 15 0.016
regulation of mitotic cell cycle GO:0007346 126 0.016
ribonucleoside monophosphate metabolic process GO:0009161 80 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
positive regulation of cell death GO:0010942 224 0.016
transmembrane transport GO:0055085 412 0.016
mapk cascade GO:0000165 281 0.016
negative regulation of molecular function GO:0044092 258 0.016
positive regulation of cell cycle process GO:0090068 61 0.016
regulation of hormone levels GO:0010817 211 0.016
positive regulation of nuclear division GO:0051785 27 0.016
positive regulation of defense response GO:0031349 124 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
blood vessel morphogenesis GO:0048514 285 0.015
regulation of mrna metabolic process GO:1903311 43 0.015
anion transport GO:0006820 177 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
atp metabolic process GO:0046034 75 0.015
microtubule based movement GO:0007018 84 0.015
stem cell division GO:0017145 30 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
positive regulation of cell cycle GO:0045787 92 0.015
innate immune response GO:0045087 157 0.014
carbohydrate homeostasis GO:0033500 128 0.014
defense response to other organism GO:0098542 197 0.014
regulation of cell motility GO:2000145 236 0.014
cell growth GO:0016049 130 0.014
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.014
regulation of mrna processing GO:0050684 41 0.014
response to organonitrogen compound GO:0010243 246 0.014
negative regulation of gene expression epigenetic GO:0045814 15 0.014
response to acid chemical GO:0001101 111 0.014
embryonic axis specification GO:0000578 30 0.014
Fly
modification dependent macromolecule catabolic process GO:0043632 133 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
Fly
organophosphate catabolic process GO:0046434 232 0.014
protein processing GO:0016485 163 0.014
peptidyl amino acid modification GO:0018193 336 0.013
regulation of protein catabolic process GO:0042176 108 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
germline stem cell asymmetric division GO:0098728 2 0.013
regulation of dna recombination GO:0000018 34 0.013
cellular chemical homeostasis GO:0055082 215 0.013
regulation of cell maturation GO:1903429 13 0.013
Fly
nuclear transcribed mrna poly a tail shortening GO:0000289 7 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
nuclear transcribed mrna catabolic process GO:0000956 16 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
positive regulation of translation GO:0045727 19 0.013
homeostasis of number of cells GO:0048872 210 0.013
regulation of transmembrane transport GO:0034762 128 0.013
stem cell development GO:0048864 219 0.013
Fly
small molecule biosynthetic process GO:0044283 132 0.013
development of primary sexual characteristics GO:0045137 143 0.013
regulation of protein maturation GO:1903317 96 0.013
glucose homeostasis GO:0042593 128 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
gonad development GO:0008406 141 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.012
blastocyst development GO:0001824 80 0.012
positive regulation of mrna 3 end processing GO:0031442 5 0.012
regulation of innate immune response GO:0045088 91 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
microtubule based process GO:0007017 236 0.012
Fly
regulation of anatomical structure size GO:0090066 178 0.012
carbohydrate metabolic process GO:0005975 230 0.012
regulation of neuron differentiation GO:0045664 281 0.012
regulation of membrane potential GO:0042391 192 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
chromatin modification GO:0016568 187 0.012
regulation of reproductive process GO:2000241 66 0.012
Fly
regulation of protein complex assembly GO:0043254 83 0.012
positive regulation of proteolysis GO:0045862 85 0.012
anatomical structure homeostasis GO:0060249 145 0.012
regulation of cellular component size GO:0032535 121 0.012
multicellular organismal signaling GO:0035637 91 0.012
regulation of cellular protein catabolic process GO:1903362 61 0.012
muscle system process GO:0003012 141 0.012
immune effector process GO:0002252 321 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.012
mesodermal cell migration GO:0008078 4 0.012
regulation of endopeptidase activity GO:0052548 89 0.011
response to oxidative stress GO:0006979 123 0.011
regulation of protein localization GO:0032880 231 0.011
protein methylation GO:0006479 81 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
positive regulation of protein modification process GO:0031401 299 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
regulation of mrna catabolic process GO:0061013 6 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
male sex differentiation GO:0046661 109 0.011
regulation of system process GO:0044057 200 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
cellular homeostasis GO:0019725 240 0.011
glycerolipid biosynthetic process GO:0045017 50 0.011
striated muscle tissue development GO:0014706 293 0.011
transmission of nerve impulse GO:0019226 76 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
endocytosis GO:0006897 168 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
regulation of cell adhesion GO:0030155 154 0.011
lateral inhibition GO:0046331 1 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
negative regulation of protein modification process GO:0031400 163 0.011
exocytosis GO:0006887 121 0.011
synapse organization GO:0050808 125 0.011
sister chromatid cohesion GO:0007062 12 0.011
adult behavior GO:0030534 135 0.011
sperm motility GO:0030317 47 0.011
neuron projection guidance GO:0097485 141 0.011
synaptonemal complex assembly GO:0007130 13 0.011
cell fate commitment GO:0045165 210 0.011
Fly
regulation of transferase activity GO:0051338 263 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
organic hydroxy compound biosynthetic process GO:1901617 77 0.010
wnt signaling pathway GO:0016055 188 0.010
inflammatory response GO:0006954 244 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
positive regulation of mrna metabolic process GO:1903313 17 0.010
anion transmembrane transport GO:0098656 71 0.010
chromatin silencing GO:0006342 15 0.010
regulation of protein ubiquitination GO:0031396 52 0.010
cofactor metabolic process GO:0051186 80 0.010
response to inorganic substance GO:0010035 96 0.010
protein localization to organelle GO:0033365 185 0.010
positive regulation of cell division GO:0051781 31 0.010
atp catabolic process GO:0006200 55 0.010
cellular alcohol metabolic process GO:0044107 3 0.010
regulation of peptidase activity GO:0052547 96 0.010
multicellular organism growth GO:0035264 161 0.010
cilium morphogenesis GO:0060271 102 0.010
single organism cell adhesion GO:0098602 156 0.010

Mael disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
disease of metabolism DOID:0014667 0 0.013
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012