Mus musculus

0 known processes

Man1a

mannosidase 1, alpha

(Aliases: PCR1,Man1a1)

Man1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glycoprotein metabolic process GO:0009100 116 0.265
Mouse
positive regulation of mapk cascade GO:0043410 170 0.150
carbohydrate derivative biosynthetic process GO:1901137 183 0.146
cytokine production GO:0001816 319 0.136
positive regulation of cellular catabolic process GO:0031331 148 0.131
glycoprotein biosynthetic process GO:0009101 89 0.130
organic cyclic compound catabolic process GO:1901361 295 0.121
regulation of transferase activity GO:0051338 263 0.118
carbohydrate metabolic process GO:0005975 230 0.117
respiratory tube development GO:0030323 167 0.113
Mouse
regulation of cytokine production GO:0001817 266 0.111
leukocyte differentiation GO:0002521 342 0.109
amine metabolic process GO:0009308 45 0.107
carbohydrate derivative catabolic process GO:1901136 231 0.107
t cell activation GO:0042110 289 0.105
adaptive immune response GO:0002250 155 0.103
positive regulation of protein phosphorylation GO:0001934 242 0.100
macromolecule catabolic process GO:0009057 281 0.094
regulation of cell activation GO:0050865 289 0.093
positive regulation of nervous system development GO:0051962 221 0.091
organonitrogen compound catabolic process GO:1901565 264 0.091
regulation of cellular catabolic process GO:0031329 242 0.091
cellular macromolecule catabolic process GO:0044265 206 0.091
regulation of response to wounding GO:1903034 189 0.088
positive regulation of protein modification process GO:0031401 299 0.087
nucleoside phosphate metabolic process GO:0006753 338 0.080
cellular amine metabolic process GO:0044106 44 0.077
immune effector process GO:0002252 321 0.076
regulation of defense response GO:0031347 233 0.076
gland development GO:0048732 330 0.076
regulation of membrane potential GO:0042391 192 0.072
regulation of lymphocyte activation GO:0051249 240 0.071
positive regulation of transferase activity GO:0051347 167 0.070
negative regulation of protein metabolic process GO:0051248 282 0.070
macromolecule glycosylation GO:0043413 55 0.070
aromatic compound catabolic process GO:0019439 286 0.069
nucleobase containing small molecule metabolic process GO:0055086 352 0.068
positive regulation of lymphocyte activation GO:0051251 140 0.068
response to endoplasmic reticulum stress GO:0034976 53 0.068
regulation of t cell activation GO:0050863 170 0.067
small gtpase mediated signal transduction GO:0007264 97 0.067
cellular amino acid metabolic process GO:0006520 103 0.067
cellular ketone metabolic process GO:0042180 84 0.067
regulation of leukocyte differentiation GO:1902105 159 0.066
regulation of intracellular transport GO:0032386 159 0.066
regulation of kinase activity GO:0043549 249 0.064
lymphocyte differentiation GO:0030098 242 0.064
cellular lipid metabolic process GO:0044255 323 0.064
protein glycosylation GO:0006486 55 0.063
cellular response to biotic stimulus GO:0071216 92 0.063
cell adhesion GO:0007155 329 0.061
regulation of hydrolase activity GO:0051336 246 0.061
positive regulation of t cell activation GO:0050870 101 0.061
response to organic cyclic compound GO:0014070 198 0.059
cellular nitrogen compound catabolic process GO:0044270 280 0.059
wound healing GO:0042060 157 0.059
b cell activation GO:0042113 161 0.059
cellular response to lipopolysaccharide GO:0071222 77 0.058
nucleotide metabolic process GO:0009117 332 0.057
protein catabolic process GO:0030163 221 0.057
purine nucleoside triphosphate metabolic process GO:0009144 226 0.056
glycosyl compound catabolic process GO:1901658 206 0.054
posttranscriptional regulation of gene expression GO:0010608 155 0.054
cellular response to lipid GO:0071396 145 0.054
nucleoside catabolic process GO:0009164 206 0.053
immune response regulating signaling pathway GO:0002764 125 0.053
negative regulation of immune system process GO:0002683 209 0.053
ribonucleoside metabolic process GO:0009119 245 0.052
transmembrane transport GO:0055085 412 0.052
ribonucleotide catabolic process GO:0009261 208 0.052
apoptotic signaling pathway GO:0097190 306 0.051
skeletal system development GO:0001501 356 0.051
cellular response to molecule of bacterial origin GO:0071219 83 0.050
lipid biosynthetic process GO:0008610 179 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
inflammatory response GO:0006954 244 0.048
purine ribonucleoside metabolic process GO:0046128 241 0.048
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.048
regulation of inflammatory response GO:0050727 147 0.048
purine nucleotide catabolic process GO:0006195 211 0.047
myeloid cell differentiation GO:0030099 233 0.047
protein autophosphorylation GO:0046777 61 0.047
response to lipopolysaccharide GO:0032496 128 0.047
epidermis development GO:0008544 187 0.047
positive regulation of defense response GO:0031349 124 0.046
mesenchyme development GO:0060485 152 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.046
cellular ion homeostasis GO:0006873 165 0.045
regulation of mapk cascade GO:0043408 248 0.045
tissue remodeling GO:0048771 102 0.044
guanosine containing compound catabolic process GO:1901069 144 0.044
cellular chemical homeostasis GO:0055082 215 0.044
purine nucleotide metabolic process GO:0006163 302 0.044
positive regulation of apoptotic process GO:0043065 217 0.043
positive regulation of cell development GO:0010720 237 0.042
positive regulation of cytokine production GO:0001819 174 0.042
immune response activating signal transduction GO:0002757 116 0.042
positive regulation of cell activation GO:0050867 158 0.041
activation of immune response GO:0002253 138 0.041
peptidyl tyrosine phosphorylation GO:0018108 143 0.041
regulation of protein kinase activity GO:0045859 232 0.041
skin development GO:0043588 220 0.040
defense response to bacterium GO:0042742 119 0.039
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.039
regulation of neuron differentiation GO:0045664 281 0.039
regulation of gtp catabolic process GO:0033124 113 0.038
nucleoside metabolic process GO:0009116 246 0.038
peptidyl tyrosine modification GO:0018212 145 0.038
cellular response to hormone stimulus GO:0032870 150 0.038
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.038
muscle cell differentiation GO:0042692 261 0.038
regulation of secretion by cell GO:1903530 249 0.037
glycosylation GO:0070085 62 0.037
sequestering of metal ion GO:0051238 19 0.037
ras protein signal transduction GO:0007265 77 0.036
circulatory system process GO:0003013 197 0.035
transmission of nerve impulse GO:0019226 76 0.035
anatomical structure homeostasis GO:0060249 145 0.034
regulation of protein serine threonine kinase activity GO:0071900 157 0.034
lipid transport GO:0006869 98 0.034
regulation of cell migration GO:0030334 219 0.034
phospholipid transport GO:0015914 21 0.034
regulation of protein localization GO:0032880 231 0.034
positive regulation of gtpase activity GO:0043547 85 0.034
regulation of purine nucleotide metabolic process GO:1900542 169 0.034
nucleoside phosphate catabolic process GO:1901292 222 0.034
organonitrogen compound biosynthetic process GO:1901566 192 0.033
cellular homeostasis GO:0019725 240 0.033
cytoplasmic transport GO:0016482 234 0.033
positive regulation of programmed cell death GO:0043068 218 0.033
regulation of nucleotide metabolic process GO:0006140 169 0.033
purine nucleoside triphosphate catabolic process GO:0009146 203 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.033
cellular protein catabolic process GO:0044257 155 0.033
glycosyl compound metabolic process GO:1901657 246 0.033
regulation of purine nucleotide catabolic process GO:0033121 122 0.033
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.033
blood circulation GO:0008015 195 0.032
response to organonitrogen compound GO:0010243 246 0.032
defense response to other organism GO:0098542 197 0.032
action potential GO:0001508 78 0.032
regulation of ras gtpase activity GO:0032318 88 0.032
organophosphate catabolic process GO:0046434 232 0.032
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
regulation of protein transport GO:0051223 163 0.032
heterocycle catabolic process GO:0046700 280 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
metal ion homeostasis GO:0055065 189 0.031
t cell differentiation GO:0030217 174 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.031
ossification GO:0001503 216 0.031
anion transport GO:0006820 177 0.031
blood vessel morphogenesis GO:0048514 285 0.030
negative regulation of cellular component organization GO:0051129 194 0.030
stem cell differentiation GO:0048863 268 0.030
peptidyl amino acid modification GO:0018193 336 0.030
response to nutrient levels GO:0031667 109 0.030
glucose homeostasis GO:0042593 128 0.030
lung development GO:0030324 164 0.030
Mouse
protein localization to organelle GO:0033365 185 0.030
nucleoside triphosphate metabolic process GO:0009141 230 0.030
cell substrate adhesion GO:0031589 130 0.030
actin filament organization GO:0007015 113 0.030
cell activation involved in immune response GO:0002263 126 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
respiratory system development GO:0060541 190 0.029
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.029
positive regulation of nucleotide metabolic process GO:0045981 114 0.029
ribonucleotide metabolic process GO:0009259 291 0.029
locomotory behavior GO:0007626 195 0.029
regulation of apoptotic signaling pathway GO:2001233 197 0.029
alcohol metabolic process GO:0006066 116 0.029
nucleotide catabolic process GO:0009166 217 0.028
leukocyte proliferation GO:0070661 172 0.028
intracellular protein transport GO:0006886 204 0.028
purine nucleoside catabolic process GO:0006152 205 0.028
positive regulation of hydrolase activity GO:0051345 148 0.028
lipid localization GO:0010876 126 0.028
lymphocyte mediated immunity GO:0002449 139 0.028
blood coagulation GO:0007596 76 0.028
regulation of nucleoside metabolic process GO:0009118 130 0.028
regulation of t cell differentiation GO:0045580 83 0.028
extrinsic apoptotic signaling pathway GO:0097191 126 0.028
regulation of organelle organization GO:0033043 289 0.028
ion transmembrane transport GO:0034220 361 0.027
cation homeostasis GO:0055080 212 0.027
positive regulation of nucleotide catabolic process GO:0030813 88 0.027
regulation of secretion GO:0051046 274 0.027
regulation of cell adhesion GO:0030155 154 0.027
phospholipid transfer to membrane GO:0006649 2 0.027
cellular calcium ion homeostasis GO:0006874 119 0.027
heart morphogenesis GO:0003007 178 0.027
calcium ion homeostasis GO:0055074 127 0.027
positive regulation of kinase activity GO:0033674 155 0.027
regulation of map kinase activity GO:0043405 120 0.026
regulation of ossification GO:0030278 112 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
lymphocyte activation involved in immune response GO:0002285 93 0.026
positive regulation of cell adhesion GO:0045785 80 0.026
positive regulation of neuron differentiation GO:0045666 141 0.026
male gamete generation GO:0048232 285 0.026
b cell differentiation GO:0030183 78 0.026
fertilization GO:0009566 127 0.026
cellular response to organonitrogen compound GO:0071417 145 0.025
purine containing compound metabolic process GO:0072521 311 0.025
lateral inhibition GO:0046331 1 0.025
regulation of lymphocyte differentiation GO:0045619 107 0.025
cellular protein complex assembly GO:0043623 116 0.025
gtp catabolic process GO:0006184 143 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
ubiquitin dependent protein catabolic process GO:0006511 129 0.025
positive regulation of ras gtpase activity GO:0032320 65 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
response to extracellular stimulus GO:0009991 127 0.025
positive regulation of map kinase activity GO:0043406 84 0.025
protein modification by small protein conjugation or removal GO:0070647 207 0.025
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.025
negative regulation of cell proliferation GO:0008285 296 0.025
nitrogen compound transport GO:0071705 271 0.024
regulation of endocytosis GO:0030100 69 0.024
regulation of leukocyte apoptotic process GO:2000106 56 0.024
regulation of homeostatic process GO:0032844 182 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
angiogenesis GO:0001525 201 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
cell type specific apoptotic process GO:0097285 268 0.024
activation of mapk activity GO:0000187 59 0.024
negative regulation of phosphate metabolic process GO:0045936 184 0.024
response to transforming growth factor beta GO:0071559 88 0.024
negative regulation of cell activation GO:0050866 111 0.024
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.024
positive regulation of protein kinase activity GO:0045860 144 0.024
multicellular organismal homeostasis GO:0048871 164 0.024
response to molecule of bacterial origin GO:0002237 143 0.024
regulation of actin cytoskeleton organization GO:0032956 84 0.024
keratinocyte differentiation GO:0030216 48 0.024
camera type eye development GO:0043010 266 0.024
response to growth factor GO:0070848 198 0.023
mitochondrion organization GO:0007005 134 0.023
mapk cascade GO:0000165 281 0.023
positive regulation of gtp catabolic process GO:0033126 85 0.023
negative regulation of ossification GO:0030279 49 0.023
regulation of nucleocytoplasmic transport GO:0046822 73 0.023
organelle fission GO:0048285 170 0.023
myelination GO:0042552 74 0.023
regulation of protein catabolic process GO:0042176 108 0.023
hepaticobiliary system development GO:0061008 67 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.023
oligosaccharide metabolic process GO:0009311 11 0.023
monocarboxylic acid metabolic process GO:0032787 191 0.023
cellular response to growth factor stimulus GO:0071363 197 0.023
renal system development GO:0072001 225 0.023
protein processing GO:0016485 163 0.022
steroid metabolic process GO:0008202 119 0.022
positive regulation of response to wounding GO:1903036 66 0.022
chemotaxis GO:0006935 247 0.022
hemostasis GO:0007599 78 0.022
myotube differentiation GO:0014902 105 0.022
rho protein signal transduction GO:0007266 32 0.022
lymphocyte proliferation GO:0046651 164 0.022
endocytosis GO:0006897 168 0.022
epithelial cell proliferation GO:0050673 174 0.022
neuronal action potential GO:0019228 54 0.022
protein maturation GO:0051604 176 0.022
guanosine containing compound metabolic process GO:1901068 144 0.022
oxidation reduction process GO:0055114 342 0.022
ribonucleoside catabolic process GO:0042454 206 0.022
stem cell development GO:0048864 219 0.022
sequestering of calcium ion GO:0051208 18 0.022
membrane organization GO:0061024 245 0.022
homeostasis of number of cells GO:0048872 210 0.022
nucleocytoplasmic transport GO:0006913 139 0.021
regulation of cytoskeleton organization GO:0051493 122 0.021
maintenance of location GO:0051235 89 0.021
regulation of intracellular protein transport GO:0033157 82 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
carbohydrate homeostasis GO:0033500 128 0.021
reactive nitrogen species metabolic process GO:2001057 0 0.021
regulation of neuron projection development GO:0010975 169 0.021
multicellular organismal signaling GO:0035637 91 0.021
nuclear transport GO:0051169 139 0.021
regulation of establishment of protein localization GO:0070201 181 0.021
ensheathment of neurons GO:0007272 76 0.021
spermatogenesis GO:0007283 284 0.021
positive regulation of proteolysis GO:0045862 85 0.021
protein localization to nucleus GO:0034504 121 0.021
glycerolipid metabolic process GO:0046486 122 0.021
negative regulation of glycoprotein metabolic process GO:1903019 3 0.021
adult behavior GO:0030534 135 0.021
positive regulation of cell death GO:0010942 224 0.021
vacuole organization GO:0007033 38 0.021
alpha beta t cell activation GO:0046631 91 0.021
gtp metabolic process GO:0046039 144 0.021
regulation of cellular response to stress GO:0080135 159 0.021
negative regulation of phosphorylation GO:0042326 166 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
regulation of alpha beta t cell activation GO:0046634 53 0.020
single organismal cell cell adhesion GO:0016337 131 0.020
learning or memory GO:0007611 148 0.020
regulation of body fluid levels GO:0050878 162 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
cellular metal ion homeostasis GO:0006875 151 0.020
epithelial tube morphogenesis GO:0060562 303 0.020
regulation of proteolysis GO:0030162 164 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.020
tissue homeostasis GO:0001894 115 0.020
t cell proliferation GO:0042098 120 0.020
divalent inorganic cation transport GO:0072511 178 0.020
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.019
positive regulation of dna templated transcription elongation GO:0032786 2 0.019
rhythmic process GO:0048511 174 0.019
coagulation GO:0050817 78 0.019
positive regulation of beta amyloid clearance GO:1900223 1 0.019
neuron death GO:0070997 154 0.019
response to light stimulus GO:0009416 135 0.019
positive regulation of protein transport GO:0051222 93 0.019
cation transport GO:0006812 399 0.019
cellular divalent inorganic cation homeostasis GO:0072503 127 0.019
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.019
wnt signaling pathway GO:0016055 188 0.019
cellular lipid catabolic process GO:0044242 52 0.019
cation transmembrane transport GO:0098655 266 0.019
erk1 and erk2 cascade GO:0070371 77 0.019
positive regulation of jun kinase activity GO:0043507 30 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
muscle system process GO:0003012 141 0.019
organic anion transport GO:0015711 137 0.019
leukocyte activation involved in immune response GO:0002366 126 0.019
sulfur compound biosynthetic process GO:0044272 37 0.019
fatty acid metabolic process GO:0006631 121 0.018
bone development GO:0060348 120 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
regulation of lipid metabolic process GO:0019216 118 0.018
regulation of b cell activation GO:0050864 81 0.018
regulation of anatomical structure size GO:0090066 178 0.018
regulation of leukocyte mediated immunity GO:0002703 104 0.018
lymphocyte apoptotic process GO:0070227 54 0.018
cd4 positive alpha beta t cell activation GO:0035710 45 0.018
myeloid cell homeostasis GO:0002262 114 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
regulation of clathrin mediated endocytosis GO:2000369 4 0.018
cell cell recognition GO:0009988 44 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
regulation of actin filament based process GO:0032970 99 0.018
rab protein signal transduction GO:0032482 1 0.018
single organism cell adhesion GO:0098602 156 0.017
axon ensheathment GO:0008366 76 0.017
mrna metabolic process GO:0016071 84 0.017
response to oxidative stress GO:0006979 123 0.017
small molecule biosynthetic process GO:0044283 132 0.017
male sex differentiation GO:0046661 109 0.017
protein import into nucleus GO:0006606 95 0.017
positive regulation of lymphocyte differentiation GO:0045621 61 0.017
single fertilization GO:0007338 82 0.017
organic hydroxy compound transport GO:0015850 93 0.017
protein targeting GO:0006605 143 0.017
organophosphate ester transport GO:0015748 28 0.017
response to peptide GO:1901652 136 0.017
regulation of cell motility GO:2000145 236 0.017
connective tissue development GO:0061448 179 0.017
response to steroid hormone GO:0048545 56 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
nuclear division GO:0000280 158 0.017
neural tube development GO:0021915 160 0.017
protein import GO:0017038 101 0.017
regulation of system process GO:0044057 200 0.017
bone remodeling GO:0046849 53 0.017
negative regulation of lymphocyte activation GO:0051250 91 0.017
regulation of binding GO:0051098 111 0.016
axonogenesis GO:0007409 274 0.016
lipid catabolic process GO:0016042 69 0.016
protein n linked glycosylation GO:0006487 12 0.016
lytic vacuole organization GO:0080171 21 0.016
regulation of leukocyte proliferation GO:0070663 121 0.016
actin cytoskeleton organization GO:0030036 220 0.016
regulation of myeloid cell differentiation GO:0045637 96 0.016
positive regulation of t cell differentiation GO:0045582 52 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.016
myotube cell development GO:0014904 60 0.016
biomineral tissue development GO:0031214 64 0.016
positive regulation of protein catabolic process GO:0045732 60 0.016
syncytium formation by plasma membrane fusion GO:0000768 42 0.016
cellular response to nutrient levels GO:0031669 64 0.016
regulation of thymocyte migration GO:2000410 2 0.016
regulation of lipid transport GO:0032368 36 0.016
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.016
sensory organ morphogenesis GO:0090596 242 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
digestive tract development GO:0048565 190 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
response to acid chemical GO:0001101 111 0.016
positive regulation of secretion by cell GO:1903532 114 0.016
muscle tissue development GO:0060537 308 0.016
triglyceride metabolic process GO:0006641 51 0.016
regulation of adaptive immune response GO:0002819 90 0.015
positive regulation of lipid transport GO:0032370 22 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.015
regulation of receptor activity GO:0010469 41 0.015
positive regulation of leukocyte differentiation GO:1902107 86 0.015
synaptic transmission GO:0007268 329 0.015
cognition GO:0050890 149 0.015
regulation of osteoblast differentiation GO:0045667 67 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
digestive system development GO:0055123 200 0.015
positive regulation of inflammatory response GO:0050729 47 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.015
alpha beta t cell differentiation GO:0046632 69 0.015
lipid homeostasis GO:0055088 63 0.015
glial cell differentiation GO:0010001 131 0.015
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.015
actin filament polymerization GO:0030041 44 0.015
regulation of neuron death GO:1901214 134 0.015
t cell activation involved in immune response GO:0002286 43 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
phospholipid metabolic process GO:0006644 87 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
sensory perception GO:0007600 245 0.015
urogenital system development GO:0001655 261 0.015
leukocyte migration GO:0050900 124 0.015
sterol transport GO:0015918 38 0.015
regulation of cell growth GO:0001558 91 0.015
leukocyte mediated immunity GO:0002443 174 0.015
sphingolipid metabolic process GO:0006665 45 0.015
negative regulation of neuron death GO:1901215 98 0.014
regulation of immunoglobulin production GO:0002637 42 0.014
gliogenesis GO:0042063 141 0.014
positive regulation of innate immune response GO:0045089 80 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
bone mineralization GO:0030282 54 0.014
innate immune response activating signal transduction GO:0002758 50 0.014
activation of janus kinase activity GO:0042976 2 0.014
mammary gland epithelium development GO:0061180 65 0.014
negative regulation of immune effector process GO:0002698 55 0.014
regulation of production of molecular mediator of immune response GO:0002700 65 0.014
negative regulation of nervous system development GO:0051961 156 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
spermatid development GO:0007286 108 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.014
regulation of lymphocyte mediated immunity GO:0002706 84 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
sulfur compound metabolic process GO:0006790 100 0.014
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.014
positive regulation of growth GO:0045927 104 0.014
epithelial cell migration GO:0010631 63 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
regulation of protein localization to nucleus GO:1900180 60 0.014
neurotransmitter secretion GO:0007269 62 0.014
t cell mediated immunity GO:0002456 50 0.014
regulation of protein secretion GO:0050708 82 0.014
purine containing compound catabolic process GO:0072523 213 0.014
positive regulation of phagocytosis engulfment GO:0060100 3 0.013
liver development GO:0001889 66 0.013
regulation of erk1 and erk2 cascade GO:0070372 71 0.013
negative regulation of myeloid cell differentiation GO:0045638 38 0.013
regulation of protein maturation GO:1903317 96 0.013
divalent metal ion transport GO:0070838 172 0.013
peptide secretion GO:0002790 114 0.013
regulation of hormone levels GO:0010817 211 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
intracellular cholesterol transport GO:0032367 3 0.013
cardiac muscle hypertrophy GO:0003300 23 0.013
regionalization GO:0003002 337 0.013
dendritic cell apoptotic process GO:0097048 3 0.013
response to radiation GO:0009314 165 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
regulation of lymphocyte apoptotic process GO:0070228 41 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
respiratory gaseous exchange GO:0007585 43 0.013
Mouse
negative regulation of transferase activity GO:0051348 85 0.013
regulation of membrane lipid distribution GO:0097035 16 0.013
regulation of cell projection organization GO:0031344 206 0.013
t cell apoptotic process GO:0070231 39 0.013
placenta development GO:0001890 140 0.013
antigen receptor mediated signaling pathway GO:0050851 64 0.013
negative regulation of growth GO:0045926 99 0.013
b cell activation involved in immune response GO:0002312 50 0.013
actin polymerization or depolymerization GO:0008154 54 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
mitotic cell cycle process GO:1903047 159 0.013
monosaccharide metabolic process GO:0005996 106 0.013

Man1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.207
inherited metabolic disorder DOID:655 0 0.207
sensory system disease DOID:0050155 0 0.079
disease of anatomical entity DOID:7 0 0.079
eye and adnexa disease DOID:1492 0 0.079
nervous system disease DOID:863 0 0.079
eye disease DOID:5614 0 0.079
retinal disease DOID:5679 0 0.037
retinal degeneration DOID:8466 0 0.037
musculoskeletal system disease DOID:17 0 0.018
connective tissue disease DOID:65 0 0.018
bone disease DOID:0080001 0 0.014