|
|
positive regulation of nfat protein import into nucleus
|
GO:0051533 |
1 |
0.539
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.447
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.421
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.307
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.305
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.282
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.279
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.270
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.234
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.234
|
Human |
|
|
immune effector process
|
GO:0002252 |
321 |
0.214
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.204
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.195
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.193
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.186
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.185
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.184
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
1 |
0.183
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.180
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.180
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.174
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.171
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.170
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.169
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.169
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.167
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.164
|
|
|
|
thermosensory behavior
|
GO:0040040 |
1 |
0.161
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.156
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.156
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.156
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.156
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.155
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.154
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.154
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.153
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.148
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.146
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.145
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.144
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.143
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.143
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.141
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.141
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.139
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.138
|
Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.138
|
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.135
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.135
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.134
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.134
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.133
|
|
|
|
inositol phosphate mediated signaling
|
GO:0048016 |
13 |
0.132
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.132
|
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
33 |
0.132
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.132
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.132
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.131
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.131
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.130
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.129
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.127
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.124
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.123
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.123
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.122
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.121
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.121
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.120
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.119
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.119
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.118
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.118
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.118
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.117
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.116
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.116
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.116
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.116
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.116
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.115
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.115
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.114
|
|
|
|
positive regulation of muscle adaptation
|
GO:0014744 |
2 |
0.112
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.112
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.111
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.111
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.110
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.109
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.108
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.108
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.108
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.108
|
Human |
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.107
|
Fly |
|
|
learning or memory
|
GO:0007611 |
148 |
0.107
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.107
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.107
|
|
|
|
cellular response to drug
|
GO:0035690 |
15 |
0.107
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.106
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.105
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.105
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.103
|
|
|
|
skeletal muscle myosin thick filament assembly
|
GO:0030241 |
1 |
0.102
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.101
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.101
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.099
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.098
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.098
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.098
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.098
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.097
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.095
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.095
|
|
|
|
skeletal myofibril assembly
|
GO:0014866 |
4 |
0.095
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.094
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.094
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.094
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.094
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.093
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.093
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.092
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.092
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.092
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.092
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.090
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
47 |
0.089
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.088
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.088
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.088
|
Human Fly |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.088
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.087
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.086
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.086
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.086
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.085
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.084
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.084
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.083
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.083
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.083
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.083
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.082
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.082
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.082
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.082
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.082
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.082
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.081
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.081
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.080
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.080
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.079
|
|
|
|
calcium ion dependent exocytosis
|
GO:0017156 |
35 |
0.079
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.078
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.078
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.078
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.078
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.078
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.078
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.077
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.077
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.077
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.076
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.075
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.075
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.075
|
|
|
|
regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061178 |
31 |
0.075
|
|
|
|
cardiac muscle hypertrophy in response to stress
|
GO:0014898 |
10 |
0.074
|
|
|
|
response to amine
|
GO:0014075 |
16 |
0.074
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.074
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.073
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.073
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.070
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.070
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.069
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.069
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.069
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.069
|
|
|
|
positive regulation of muscle hypertrophy
|
GO:0014742 |
2 |
0.069
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.068
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.068
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.068
|
|
|
|
learning
|
GO:0007612 |
98 |
0.068
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.068
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.068
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.067
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.067
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.067
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.066
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.066
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.066
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.066
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.065
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.065
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.065
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.064
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.063
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.063
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.063
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.063
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.063
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.063
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.062
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.062
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.062
|
|
|
|
cellular response to glucose stimulus
|
GO:0071333 |
45 |
0.061
|
|
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.061
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.060
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.060
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.060
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.060
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.060
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.060
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.060
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.059
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.059
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.059
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.059
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.058
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.058
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.058
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.058
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.058
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.058
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.057
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.057
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.057
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.057
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.057
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.056
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.055
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.055
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.055
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.054
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.054
|
|
|
|
nfat protein import into nucleus
|
GO:0051531 |
6 |
0.054
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.054
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.054
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.054
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.054
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.053
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.053
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.053
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.052
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.052
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.052
|
|
|
|
regulation of nfat protein import into nucleus
|
GO:0051532 |
4 |
0.052
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.052
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.052
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.052
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.051
|
Fly |
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.051
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.051
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.051
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.051
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.051
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.051
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.051
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.050
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.050
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.050
|
|
|
|
sleep
|
GO:0030431 |
7 |
0.050
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.050
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.050
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.049
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.049
|
|
|
|
striated muscle adaptation
|
GO:0014888 |
26 |
0.049
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.049
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.049
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.049
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.048
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.048
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.048
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
26 |
0.048
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.048
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.048
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.047
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.047
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.047
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.047
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.047
|
|
|
|
cellular response to hexose stimulus
|
GO:0071331 |
47 |
0.047
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.047
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.047
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.047
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.047
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.047
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.047
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.047
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.046
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.046
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.046
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.046
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.046
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.046
|
Human Fly |
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.046
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.046
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.045
|
Human |
|
|
rap protein signal transduction
|
GO:0032486 |
3 |
0.045
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.045
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.045
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.045
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.045
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.045
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.045
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.045
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.045
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.044
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.044
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.044
|
|
|
|
response to amphetamine
|
GO:0001975 |
16 |
0.044
|
|
|
|
memory
|
GO:0007613 |
58 |
0.044
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.044
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.044
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.043
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.043
|
Human |
|
|
regionalization
|
GO:0003002 |
337 |
0.043
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.043
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.043
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.043
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.043
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.043
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.043
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.043
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.042
|
|
|
|
intraspecies interaction between organisms
|
GO:0051703 |
21 |
0.042
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.042
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.042
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.042
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.042
|
Fly |
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.042
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.042
|
Human Fly |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.042
|
Fly |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.041
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.041
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.041
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.041
|
|
|
|
regulation of t cell mediated cytotoxicity
|
GO:0001914 |
18 |
0.041
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.041
|
|
|
|
regulation of skeletal muscle adaptation
|
GO:0014733 |
12 |
0.041
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.040
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.040
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.040
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.040
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.040
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.040
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.040
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.040
|
|
|
|
regulation of muscle hypertrophy
|
GO:0014743 |
13 |
0.040
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.039
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.039
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.039
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.039
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.039
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.038
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.038
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.038
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.038
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.037
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.037
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.037
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.037
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.037
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.037
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.037
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.037
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.037
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.037
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.036
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.036
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.036
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.036
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.035
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.035
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.035
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.034
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.034
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.034
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.034
|
|
|
|
muscle hypertrophy
|
GO:0014896 |
24 |
0.034
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.034
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.034
|
|
|
|
apical constriction
|
GO:0003383 |
4 |
0.034
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.033
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.033
|
|
|
|
positive regulation of insulin secretion
|
GO:0032024 |
26 |
0.033
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.033
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.032
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.032
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.032
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.032
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.032
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.032
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.032
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.032
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.032
|
|
|
|
cardiac muscle hypertrophy
|
GO:0003300 |
23 |
0.032
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.032
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.032
|
|
|
|
cellular glucose homeostasis
|
GO:0001678 |
52 |
0.032
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.031
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.031
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.031
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.031
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.031
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.031
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.031
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.031
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.031
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.031
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.030
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.030
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.030
|
|
|
|
striated muscle hypertrophy
|
GO:0014897 |
24 |
0.030
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.030
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.030
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.030
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.030
|
Fly |
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.030
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.030
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.030
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.030
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.030
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
26 |
0.030
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.030
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.030
|
Human |
|
|
placenta development
|
GO:0001890 |
140 |
0.030
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.030
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.030
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.029
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.029
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.029
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.029
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.029
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.029
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.029
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.029
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.029
|
|
|
|
transition between fast and slow fiber
|
GO:0014883 |
9 |
0.028
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.028
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
15 |
0.028
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.028
|
|
|
|
insulin secretion involved in cellular response to glucose stimulus
|
GO:0035773 |
36 |
0.028
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.028
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.028
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.028
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.028
|
|
|
|
skeletal muscle adaptation
|
GO:0043501 |
16 |
0.027
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.027
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.027
|
|
|
|
lung epithelium development
|
GO:0060428 |
37 |
0.027
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.027
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.027
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.027
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.027
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.027
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.027
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.027
|
|
|
|
positive regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0035774 |
13 |
0.027
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.026
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.026
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.026
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.026
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.026
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.026
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.026
|
|
|
|
carbon catabolite activation of transcription from rna polymerase ii promoter
|
GO:0000436 |
4 |
0.026
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.026
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.026
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.026
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.026
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.026
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.026
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.026
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.026
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.026
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.026
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.026
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.026
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.026
|
Human |
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.026
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.026
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.025
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.025
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.025
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.025
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.025
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.025
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.025
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.025
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.025
|
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
31 |
0.025
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.025
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.025
|
|
