Mus musculus

327 known processes

Mapk14

mitogen-activated protein kinase 14

(Aliases: Csbp1,Mxi2,CSBP2,p38MAPK,p38alpha,MGC102436,p38,p38-alpha,p38a,Crk1,PRKM15,PRKM14)

Mapk14 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nuclear cell cycle dna replication GO:0033262 2 1.000
Yeast
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 1.000
cellular response to arsenic containing substance GO:0071243 4 1.000
Fly
positive regulation of brown fat cell differentiation GO:0090336 4 1.000
jun phosphorylation GO:0007258 41 1.000
Mouse
osmosensory signaling pathway GO:0007231 1 1.000
Yeast
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 1.000
Yeast
response to osmotic stress GO:0006970 21 1.000
Yeast Worm Fly
response to oxygen radical GO:0000305 16 1.000
Worm
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 1.000
Yeast
cellular response to nitric oxide GO:0071732 4 1.000
Mouse
hyperosmotic response GO:0006972 4 0.999
Yeast Worm
fatty acid oxidation GO:0019395 28 0.999
peptidyl threonine phosphorylation GO:0018107 31 0.999
Mouse
response to superoxide GO:0000303 16 0.999
Worm
p38mapk cascade GO:0038066 4 0.998
response to nitric oxide GO:0071731 4 0.998
Mouse
regulation of brown fat cell differentiation GO:0090335 5 0.998
response to arsenic containing substance GO:0046685 5 0.998
Yeast Fly
jnk cascade GO:0007254 72 0.997
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.997
stress activated protein kinase signaling cascade GO:0031098 81 0.997
lipid modification GO:0030258 65 0.996
cellular response to growth factor stimulus GO:0071363 197 0.994
Human Fly
cartilage condensation GO:0001502 18 0.992
nuclear dna replication GO:0033260 3 0.992
Yeast
stress activated mapk cascade GO:0051403 80 0.991
myeloid cell homeostasis GO:0002262 114 0.991
peptidyl serine modification GO:0018209 83 0.990
response to reactive oxygen species GO:0000302 56 0.988
Mouse Worm Fly
chondrocyte differentiation GO:0002062 72 0.987
monosaccharide metabolic process GO:0005996 106 0.985
cellular response to reactive nitrogen species GO:1902170 5 0.983
Mouse
positive regulation of apoptotic process GO:0043065 217 0.983
Mouse
regulation of cellular response to stress GO:0080135 159 0.983
Fly
paracrine signaling GO:0038001 1 0.982
Fly
peptidyl serine phosphorylation GO:0018105 74 0.982
regulation of myoblast differentiation GO:0045661 29 0.981
regulation of terminal button organization GO:2000331 1 0.981
Fly
defense response to other organism GO:0098542 197 0.980
Worm Fly
brown fat cell differentiation GO:0050873 36 0.980
lipid oxidation GO:0034440 29 0.979
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.979
cellular response to lipopolysaccharide GO:0071222 77 0.977
cellular response to molecule of bacterial origin GO:0071219 83 0.973
response to growth factor GO:0070848 198 0.972
Human Fly
dna damage checkpoint GO:0000077 26 0.971
dna replication GO:0006260 52 0.971
Yeast
regulation of innate immune response GO:0045088 91 0.968
Fly
response to lipopolysaccharide GO:0032496 128 0.967
regulation of erythrocyte differentiation GO:0045646 23 0.966
regulation of dna replication GO:0006275 17 0.964
Yeast
positive regulation of determination of dorsal identity GO:2000017 2 0.962
Mouse
response to oxidative stress GO:0006979 123 0.957
Mouse Worm Fly
regulation of fat cell differentiation GO:0045598 81 0.957
innate immune response GO:0045087 157 0.956
Worm Fly
osteoclast differentiation GO:0030316 62 0.954
fatty acid metabolic process GO:0006631 121 0.951
regulation of jnk cascade GO:0046328 62 0.951
regulation of dna dependent dna replication GO:0090329 8 0.950
Yeast
regulation of skeletal muscle fiber development GO:0048742 36 0.948
positive regulation of myoblast differentiation GO:0045663 8 0.948
cellular response to biotic stimulus GO:0071216 92 0.946
regulation of defense response GO:0031347 233 0.946
Fly
regulation of determination of dorsal identity GO:2000015 3 0.945
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.945
mapk cascade GO:0000165 281 0.944
dna metabolic process GO:0006259 303 0.939
Yeast
canonical wnt signaling pathway GO:0060070 130 0.938
hexose metabolic process GO:0019318 98 0.937
leukocyte differentiation GO:0002521 342 0.933
positive regulation of myeloid cell differentiation GO:0045639 43 0.933
humoral immune response GO:0006959 57 0.931
Fly
cellular response to lipid GO:0071396 145 0.921
dna integrity checkpoint GO:0031570 28 0.921
terminal button organization GO:0072553 3 0.920
Fly
response to molecule of bacterial origin GO:0002237 143 0.920
regulation of cellular response to oxidative stress GO:1900407 19 0.918
Fly
positive regulation of cell death GO:0010942 224 0.918
Mouse
connective tissue development GO:0061448 179 0.918
wound healing GO:0042060 157 0.916
defense response to bacterium GO:0042742 119 0.916
Worm Fly
negative regulation of jun kinase activity GO:0043508 9 0.914
cellular response to osmotic stress GO:0071470 7 0.912
Yeast
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.911
regulation of protein targeting GO:1903533 61 0.905
fat cell differentiation GO:0045444 160 0.905
oxidation reduction process GO:0055114 342 0.905
regulation of mapk cascade GO:0043408 248 0.900
skeletal system morphogenesis GO:0048705 203 0.898
activation of innate immune response GO:0002218 56 0.897
regulation of response to oxidative stress GO:1902882 19 0.893
Fly
regulation of stress activated mapk cascade GO:0032872 69 0.892
skeletal system development GO:0001501 356 0.876
angiogenesis GO:0001525 201 0.875
positive regulation of protein modification process GO:0031401 299 0.875
Fly
response to heat GO:0009408 27 0.873
Yeast Fly
syncytium formation GO:0006949 43 0.871
response to inorganic substance GO:0010035 96 0.869
Mouse Worm Fly
negative regulation of phosphorylation GO:0042326 166 0.869
response to muramyl dipeptide GO:0032495 9 0.867
response to hydrogen peroxide GO:0042542 32 0.863
Mouse Fly
homeostasis of number of cells GO:0048872 210 0.863
reactive oxygen species metabolic process GO:0072593 84 0.861
Human Fly
cellular response to oxidative stress GO:0034599 76 0.856
Mouse Fly
regulation of cell cycle process GO:0010564 160 0.853
Yeast
regulation of myotube differentiation GO:0010830 62 0.853
carbohydrate metabolic process GO:0005975 230 0.842
cellular response to inorganic substance GO:0071241 37 0.841
Mouse Fly
regulation of cell size GO:0008361 72 0.839
Fly
intra s dna damage checkpoint GO:0031573 4 0.839
muscle fiber development GO:0048747 76 0.837
regulation of protein localization GO:0032880 231 0.835
regulation of protein kinase activity GO:0045859 232 0.833
myotube cell development GO:0014904 60 0.826
determination of dorsal ventral asymmetry GO:0048262 5 0.820
Mouse
myeloid cell differentiation GO:0030099 233 0.817
monocarboxylic acid metabolic process GO:0032787 191 0.813
cellular response to abiotic stimulus GO:0071214 56 0.812
Human Yeast
determination of dorsal identity GO:0048263 5 0.805
Mouse
muscle tissue development GO:0060537 308 0.801
regulation of myeloid cell differentiation GO:0045637 96 0.801
skeletal muscle tissue regeneration GO:0043403 20 0.795
ras protein signal transduction GO:0007265 77 0.795
regulation of cellular component size GO:0032535 121 0.795
Fly
positive regulation of protein localization to nucleus GO:1900182 30 0.794
regulation of bmp signaling pathway GO:0030510 60 0.792
Fly
negative regulation of map kinase activity GO:0043407 34 0.780
cellular response to metal ion GO:0071248 31 0.775
Fly
positive regulation of intracellular transport GO:0032388 70 0.773
dna dependent dna replication GO:0006261 24 0.772
Yeast
positive regulation of cytoplasmic transport GO:1903651 40 0.771
positive regulation of fat cell differentiation GO:0045600 32 0.768
peptidyl threonine modification GO:0018210 31 0.767
Mouse
cartilage development GO:0051216 140 0.764
regulation of map kinase activity GO:0043405 120 0.761
muscle cell development GO:0055001 133 0.754
blood vessel morphogenesis GO:0048514 285 0.750
skeletal muscle fiber development GO:0048741 58 0.726
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.722
regulation of cytoplasmic transport GO:1903649 112 0.721
tissue regeneration GO:0042246 22 0.717
protein localization to nucleus GO:0034504 121 0.715
regulation of cellular ketone metabolic process GO:0010565 66 0.714
cellular senescence GO:0090398 11 0.713
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.712
Human
regulation of muscle tissue development GO:1901861 97 0.712
cell cycle checkpoint GO:0000075 47 0.705
cell aggregation GO:0098743 18 0.698
regulation of antimicrobial humoral response GO:0002759 3 0.691
Fly
positive regulation of protein phosphorylation GO:0001934 242 0.687
Fly
protein localization to organelle GO:0033365 185 0.687
peptidyl amino acid modification GO:0018193 336 0.686
response to organonitrogen compound GO:0010243 246 0.681
regulation of wnt signaling pathway GO:0030111 123 0.675
negative regulation of intracellular signal transduction GO:1902532 167 0.673
regulation of intracellular transport GO:0032386 159 0.668
regulation of homeostatic process GO:0032844 182 0.665
cell aging GO:0007569 35 0.665
Human
negative regulation of immune system process GO:0002683 209 0.663
Fly
immune response activating signal transduction GO:0002757 116 0.663
cellular lipid metabolic process GO:0044255 323 0.658
skeletal muscle organ development GO:0060538 163 0.657
response to metal ion GO:0010038 47 0.654
Mouse Fly
positive regulation of myotube differentiation GO:0010831 24 0.653
positive regulation of programmed cell death GO:0043068 218 0.649
Mouse
regulation of protein import into nucleus GO:0042306 52 0.648
heart morphogenesis GO:0003007 178 0.645
Fly
negative regulation of wnt signaling pathway GO:0030178 73 0.644
regulation of kinase activity GO:0043549 249 0.644
negative regulation of protein phosphorylation GO:0001933 126 0.636
ossification GO:0001503 216 0.630
Mouse
positive regulation of innate immune response GO:0045089 80 0.629
multicellular organism growth GO:0035264 161 0.626
Fly
regulation of jun kinase activity GO:0043506 40 0.623
regionalization GO:0003002 337 0.622
Mouse
protein targeting GO:0006605 143 0.613
response to starvation GO:0042594 65 0.606
Fly
negative regulation of phosphate metabolic process GO:0045936 184 0.606
regulation of apoptotic signaling pathway GO:2001233 197 0.605
Mouse
syncytium formation by plasma membrane fusion GO:0000768 42 0.604
nuclear transport GO:0051169 139 0.603
organ or tissue specific immune response GO:0002251 13 0.603
Fly
myoblast differentiation GO:0045445 52 0.592
regulation of intracellular protein transport GO:0033157 82 0.589
positive regulation of protein import into nucleus GO:0042307 26 0.588
negative regulation of protein modification process GO:0031400 163 0.585
protein autophosphorylation GO:0046777 61 0.581
Rat
cytokine production GO:0001816 319 0.576
response to peptide GO:1901652 136 0.574
cytoplasmic transport GO:0016482 234 0.571
lateral inhibition GO:0046331 1 0.563
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.562
inflammatory response GO:0006954 244 0.561
positive regulation of cell size GO:0045793 5 0.558
Fly
3 utr mediated mrna stabilization GO:0070935 2 0.543
positive regulation of hydrolase activity GO:0051345 148 0.542
positive regulation of striated muscle cell differentiation GO:0051155 35 0.539
muscle cell differentiation GO:0042692 261 0.527
autophagy GO:0006914 45 0.523
cellular response to dna damage stimulus GO:0006974 207 0.518
regulation of tor signaling GO:0032006 17 0.509
positive regulation of intracellular protein transport GO:0090316 42 0.507
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.502
Fly
negative regulation of multi organism process GO:0043901 68 0.496
Fly
engulfment of apoptotic cell GO:0043652 3 0.489
defense response to gram positive bacterium GO:0050830 50 0.483
Worm
regulation of protein serine threonine kinase activity GO:0071900 157 0.482
circulatory system process GO:0003013 197 0.472
glucose metabolic process GO:0006006 92 0.472
nucleocytoplasmic transport GO:0006913 139 0.471
myotube differentiation GO:0014902 105 0.465
erythrocyte differentiation GO:0030218 88 0.463
regulation of protein localization to nucleus GO:1900180 60 0.458
small gtpase mediated signal transduction GO:0007264 97 0.448
regulation of transferase activity GO:0051338 263 0.447
striated muscle cell development GO:0055002 125 0.444
cellular amino acid metabolic process GO:0006520 103 0.440
regulation of protein transport GO:0051223 163 0.438
positive regulation of defense response GO:0031349 124 0.434
innate immune response activating signal transduction GO:0002758 50 0.433
regulation of multi organism process GO:0043900 111 0.431
Fly
striated muscle tissue development GO:0014706 293 0.431
amine metabolic process GO:0009308 45 0.431
apoptotic signaling pathway GO:0097190 306 0.428
Mouse
immune response regulating signaling pathway GO:0002764 125 0.412
epiboly GO:0090504 8 0.402
placenta development GO:0001890 140 0.401
single organism nuclear import GO:1902593 95 0.397
negative regulation of humoral immune response GO:0002921 6 0.392
Fly
regulation of anatomical structure size GO:0090066 178 0.388
Fly
regulation of striated muscle cell differentiation GO:0051153 81 0.381
response to light stimulus GO:0009416 135 0.381
pattern recognition receptor signaling pathway GO:0002221 47 0.377
negative regulation of phosphorus metabolic process GO:0010563 184 0.376
regulation of nucleocytoplasmic transport GO:0046822 73 0.374
intracellular protein transport GO:0006886 204 0.372
determination of adult lifespan GO:0008340 11 0.371
Fly
positive regulation of cellular catabolic process GO:0031331 148 0.365
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.364
negative regulation of protein metabolic process GO:0051248 282 0.356
response to nutrient levels GO:0031667 109 0.352
Fly
response to extracellular stimulus GO:0009991 127 0.348
Fly
regulation of cytokine production GO:0001817 266 0.347
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.338
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.329
Human
regulation of cell motility GO:2000145 236 0.326
regeneration GO:0031099 38 0.322
regulation of membrane potential GO:0042391 192 0.319
toll like receptor signaling pathway GO:0002224 38 0.319
cellular amine metabolic process GO:0044106 44 0.315
axon regeneration GO:0031103 12 0.313
negative regulation of tor signaling GO:0032007 13 0.313
negative regulation of kinase activity GO:0033673 81 0.312
positive regulation of muscle cell differentiation GO:0051149 39 0.311
morphogenesis of an epithelial sheet GO:0002011 27 0.306
response to transforming growth factor beta GO:0071559 88 0.303
Fly
pigment metabolic process GO:0042440 32 0.303
negative regulation of mapk cascade GO:0043409 65 0.303
defense response to fungus GO:0050832 12 0.300
Fly
regulation of ras protein signal transduction GO:0046578 114 0.298
positive regulation of protein kinase activity GO:0045860 144 0.290
regulation of cell cycle GO:0051726 281 0.290
Yeast
camera type eye development GO:0043010 266 0.274
gastrulation GO:0007369 116 0.272
positive regulation of homeostatic process GO:0032846 64 0.263
regulation of cellular catabolic process GO:0031329 242 0.263
protein modification by small protein conjugation GO:0032446 187 0.262
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.261
cellular ketone metabolic process GO:0042180 84 0.261
anion transport GO:0006820 177 0.260
regulation of cellular amino acid metabolic process GO:0006521 5 0.260
regulation of system process GO:0044057 200 0.256
wnt signaling pathway GO:0016055 188 0.253
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.245
vesicle localization GO:0051648 86 0.245
positive regulation of mapk cascade GO:0043410 170 0.241
glial cell differentiation GO:0010001 131 0.240
positive regulation of autophagy GO:0010508 9 0.239
reactive oxygen species biosynthetic process GO:1903409 8 0.232
positive regulation of map kinase activity GO:0043406 84 0.232
regulation of dna templated transcription in response to stress GO:0043620 9 0.230
Yeast
antimicrobial humoral response GO:0019730 11 0.227
Fly
ectodermal digestive tract development GO:0007439 1 0.223
regulation of lipid metabolic process GO:0019216 118 0.221
activation of mapk activity GO:0000187 59 0.219
regulation of hydrolase activity GO:0051336 246 0.217
stress induced premature senescence GO:0090400 2 0.217
Human
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.216
regulation of endopeptidase activity GO:0052548 89 0.211
digestive tract morphogenesis GO:0048546 147 0.210
positive regulation of protein transport GO:0051222 93 0.209
tor signaling GO:0031929 21 0.208
nucleoside phosphate metabolic process GO:0006753 338 0.207
action potential GO:0001508 78 0.207
activation of immune response GO:0002253 138 0.204
cellular response to radiation GO:0071478 28 0.204
Human
gland development GO:0048732 330 0.202
development of primary sexual characteristics GO:0045137 143 0.198
Worm
regulation of cysteine type endopeptidase activity GO:2000116 65 0.197
positive regulation of jnk cascade GO:0046330 46 0.195
negative regulation of transferase activity GO:0051348 85 0.195
establishment of protein localization to organelle GO:0072594 118 0.193
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.191
release of cytochrome c from mitochondria GO:0001836 23 0.191
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.188
positive regulation of ion transport GO:0043270 65 0.187
mitochondrion organization GO:0007005 134 0.187
fibroblast proliferation GO:0048144 35 0.184
negative regulation of cellular protein metabolic process GO:0032269 247 0.184
activation of mapk activity involved in innate immune response GO:0035419 2 0.183
response to cadmium ion GO:0046686 8 0.181
Mouse Fly
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.181
response to drug GO:0042493 75 0.179
positive regulation of growth GO:0045927 104 0.178
Fly
regulation of osteoblast differentiation GO:0045667 67 0.177
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.176
nucleobase containing small molecule metabolic process GO:0055086 352 0.176
epithelial tube morphogenesis GO:0060562 303 0.175
posttranscriptional regulation of gene expression GO:0010608 155 0.171
negative regulation of cell cycle GO:0045786 123 0.170
positive regulation of lipid metabolic process GO:0045834 40 0.170
central nervous system neuron differentiation GO:0021953 162 0.166
actin filament based movement GO:0030048 23 0.165
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.164
protein maturation GO:0051604 176 0.159
transmission of nerve impulse GO:0019226 76 0.159
cellular response to cadmium ion GO:0071276 3 0.159
Fly
defense response to gram negative bacterium GO:0050829 28 0.155
Worm
necrotic cell death GO:0070265 30 0.154
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.154
positive regulation of peptidase activity GO:0010952 49 0.153
epithelial cell proliferation GO:0050673 174 0.153
regulation of ion transport GO:0043269 215 0.152
regulation of myeloid leukocyte differentiation GO:0002761 58 0.151
regulation of inflammatory response GO:0050727 147 0.150
single organismal cell cell adhesion GO:0016337 131 0.149
regulation of peptidase activity GO:0052547 96 0.149
hemostasis GO:0007599 78 0.148
cellular response to external stimulus GO:0071496 88 0.147
response to radiation GO:0009314 165 0.146
Human
neuron projection regeneration GO:0031102 14 0.146
phagocytosis GO:0006909 66 0.145
regulation of endocytosis GO:0030100 69 0.145
male courtship behavior GO:0008049 2 0.143
positive regulation of endopeptidase activity GO:0010950 43 0.142
negative regulation of cellular amine metabolic process GO:0033239 1 0.142
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.138
regulation of engulfment of apoptotic cell GO:1901074 2 0.138
ovulation cycle GO:0042698 59 0.137
positive regulation of erythrocyte differentiation GO:0045648 11 0.137
pinocytosis GO:0006907 6 0.137
regulation of organelle organization GO:0033043 289 0.135
cellular response to cytokine stimulus GO:0071345 189 0.134
regulation of interleukin 6 production GO:0032675 55 0.133
nuclear import GO:0051170 95 0.132
single organism cell adhesion GO:0098602 156 0.132
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.130
positive regulation of cell migration GO:0030335 109 0.130
regulation of cell migration GO:0030334 219 0.128
synapse organization GO:0050808 125 0.127
Fly
mrna stabilization GO:0048255 9 0.126
mammary gland epithelium development GO:0061180 65 0.126
chromatin modification GO:0016568 187 0.125
regulation of ion homeostasis GO:2000021 64 0.124
positive regulation of transferase activity GO:0051347 167 0.124
response to endoplasmic reticulum stress GO:0034976 53 0.123
regulation of fatty acid metabolic process GO:0019217 28 0.120
digestive system development GO:0055123 200 0.119
endomembrane system organization GO:0010256 147 0.118
regulation of body fluid levels GO:0050878 162 0.117
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.117
cytokine metabolic process GO:0042107 71 0.117
learning or memory GO:0007611 148 0.116
positive regulation of cellular amine metabolic process GO:0033240 5 0.115
response to uv GO:0009411 44 0.114
placenta blood vessel development GO:0060674 31 0.114
negative regulation of ras protein signal transduction GO:0046580 18 0.113
apoptotic mitochondrial changes GO:0008637 48 0.113
regulation of response to drug GO:2001023 2 0.112
positive regulation of stress activated mapk cascade GO:0032874 48 0.112
neuronal action potential GO:0019228 54 0.112
regulation of tumor necrosis factor production GO:0032680 49 0.111
negative regulation of neuron apoptotic process GO:0043524 92 0.111
embryonic organ morphogenesis GO:0048562 276 0.110
multicellular organismal signaling GO:0035637 91 0.109
regulation of response to biotic stimulus GO:0002831 38 0.108
Fly
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.107
macroautophagy GO:0016236 21 0.107
mitochondrial transport GO:0006839 36 0.107
organic acid transport GO:0015849 101 0.106
protein import into nucleus GO:0006606 95 0.105
rna stabilization GO:0043489 9 0.105
embryonic placenta development GO:0001892 98 0.103
negative regulation of dna replication GO:0008156 4 0.103
regulation of establishment of protein localization GO:0070201 181 0.102
positive regulation of kinase activity GO:0033674 155 0.101
stem cell development GO:0048864 219 0.101
labyrinthine layer development GO:0060711 49 0.100
regulation of mrna stability GO:0043488 23 0.100
regulation of transforming growth factor beta2 production GO:0032909 2 0.099
gliogenesis GO:0042063 141 0.099
negative regulation of neuron death GO:1901215 98 0.099
liver development GO:0001889 66 0.098
regulation of autophagy GO:0010506 30 0.097
monocyte differentiation GO:0030224 9 0.096
organic hydroxy compound metabolic process GO:1901615 203 0.096
cell cycle arrest GO:0007050 37 0.095
spermatogenesis GO:0007283 284 0.095
lung development GO:0030324 164 0.094
regulation of ion transmembrane transport GO:0034765 119 0.094
monocarboxylic acid transport GO:0015718 44 0.093
dendrite development GO:0016358 115 0.093
membrane invagination GO:0010324 17 0.092
organic anion transport GO:0015711 137 0.092
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.091
Fly
nucleoside phosphate biosynthetic process GO:1901293 79 0.091
immune effector process GO:0002252 321 0.090
ensheathment of neurons GO:0007272 76 0.089
cellular response to vascular endothelial growth factor stimulus GO:0035924 11 0.089
Human
neuron death GO:0070997 154 0.088
multicellular organismal aging GO:0010259 24 0.088
Fly
regulation of tube size GO:0035150 57 0.087
blastocyst development GO:0001824 80 0.087
lipid localization GO:0010876 126 0.086
blood circulation GO:0008015 195 0.085
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.085
regulation of neuron death GO:1901214 134 0.084
heart process GO:0003015 94 0.084
microglial cell activation GO:0001774 3 0.083
regulation of keratinocyte differentiation GO:0045616 11 0.083
regulation of fibroblast proliferation GO:0048145 34 0.082
translational initiation GO:0006413 24 0.082
positive regulation of gtpase activity GO:0043547 85 0.082
regulation of organ morphogenesis GO:2000027 144 0.082
regulation of protein autophosphorylation GO:0031952 8 0.081
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.081
genetic imprinting GO:0071514 27 0.080
activation of adenylate cyclase activity GO:0007190 4 0.080
intrinsic apoptotic signaling pathway GO:0097193 132 0.080
determination of left right symmetry GO:0007368 80 0.080
keratinocyte differentiation GO:0030216 48 0.080
protein kinase b signaling GO:0043491 74 0.079
lipid transport GO:0006869 98 0.079
phenol containing compound metabolic process GO:0018958 60 0.079
protein modification by small protein conjugation or removal GO:0070647 207 0.078
b cell differentiation GO:0030183 78 0.078
establishment of vesicle localization GO:0051650 81 0.077
positive regulation of proteolysis GO:0045862 85 0.077
embryonic digestive tract development GO:0048566 27 0.076
antibacterial humoral response GO:0019731 8 0.076
regulation of stem cell maintenance GO:2000036 17 0.076
male gamete generation GO:0048232 285 0.076
regulation of cellular amine metabolic process GO:0033238 20 0.075
regulation of cytokine biosynthetic process GO:0042035 59 0.075
positive regulation of osteoblast differentiation GO:0045669 34 0.075
determination of digestive tract left right asymmetry GO:0071907 1 0.075
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.074
muscle contraction GO:0006936 101 0.074
regulation of transporter activity GO:0032409 57 0.073
negative regulation of nervous system development GO:0051961 156 0.073
cellular response to nutrient levels GO:0031669 64 0.073
inorganic ion transmembrane transport GO:0098660 234 0.073
response to temperature stimulus GO:0009266 55 0.073
Yeast Fly
regulation of mitotic cell cycle GO:0007346 126 0.072
respiratory tube development GO:0030323 167 0.072
fibroblast migration GO:0010761 21 0.072
regulation of fatty acid biosynthetic process GO:0042304 12 0.070
endocytosis GO:0006897 168 0.070
negative regulation of jnk cascade GO:0046329 12 0.069
organophosphate biosynthetic process GO:0090407 122 0.068
regulation of cellular protein catabolic process GO:1903362 61 0.067
myeloid leukocyte activation GO:0002274 83 0.066
positive regulation of cellular protein catabolic process GO:1903364 34 0.065
post embryonic retina morphogenesis in camera type eye GO:0060060 3 0.065
organonitrogen compound biosynthetic process GO:1901566 192 0.065
mitochondrial membrane organization GO:0007006 26 0.065
cellular response to peptide hormone stimulus GO:0071375 92 0.064
t cell activation GO:0042110 289 0.064
carboxylic acid biosynthetic process GO:0046394 86 0.064
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 7 0.064
negative regulation of growth GO:0045926 99 0.063
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 6 0.063
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 11 0.063
apoptotic cell clearance GO:0043277 17 0.063
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.063
Human
forebrain development GO:0030900 302 0.063
cardiac muscle contraction GO:0060048 32 0.063
cellular response to light stimulus GO:0071482 19 0.062
negative regulation of mitotic cell cycle GO:0045930 58 0.062
respiratory system development GO:0060541 190 0.062
multi multicellular organism process GO:0044706 109 0.062
regulation of nucleotide metabolic process GO:0006140 169 0.062

Mapk14 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.281
disease of cellular proliferation DOID:14566 0 0.281
organ system cancer DOID:0050686 0 0.277