|
regulation of nuclear cell cycle dna replication
|
GO:0033262 |
2 |
1.000
|
Yeast |
|
myoblast differentiation involved in skeletal muscle regeneration
|
GO:0014835 |
3 |
1.000
|
|
|
cellular response to arsenic containing substance
|
GO:0071243 |
4 |
1.000
|
Fly |
|
positive regulation of brown fat cell differentiation
|
GO:0090336 |
4 |
1.000
|
|
|
jun phosphorylation
|
GO:0007258 |
41 |
1.000
|
Mouse |
|
osmosensory signaling pathway
|
GO:0007231 |
1 |
1.000
|
Yeast |
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
8 |
1.000
|
Yeast |
|
response to osmotic stress
|
GO:0006970 |
21 |
1.000
|
Yeast Worm Fly |
|
response to oxygen radical
|
GO:0000305 |
16 |
1.000
|
Worm |
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
1.000
|
Yeast |
|
cellular response to nitric oxide
|
GO:0071732 |
4 |
1.000
|
Mouse |
|
hyperosmotic response
|
GO:0006972 |
4 |
0.999
|
Yeast Worm |
|
fatty acid oxidation
|
GO:0019395 |
28 |
0.999
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.999
|
Mouse |
|
response to superoxide
|
GO:0000303 |
16 |
0.999
|
Worm |
|
p38mapk cascade
|
GO:0038066 |
4 |
0.998
|
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.998
|
Mouse |
|
regulation of brown fat cell differentiation
|
GO:0090335 |
5 |
0.998
|
|
|
response to arsenic containing substance
|
GO:0046685 |
5 |
0.998
|
Yeast Fly |
|
jnk cascade
|
GO:0007254 |
72 |
0.997
|
Mouse |
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.997
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.997
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.996
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.994
|
Human Fly |
|
cartilage condensation
|
GO:0001502 |
18 |
0.992
|
|
|
nuclear dna replication
|
GO:0033260 |
3 |
0.992
|
Yeast |
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.991
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.991
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.990
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.988
|
Mouse Worm Fly |
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.987
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.985
|
|
|
cellular response to reactive nitrogen species
|
GO:1902170 |
5 |
0.983
|
Mouse |
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.983
|
Mouse |
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.983
|
Fly |
|
paracrine signaling
|
GO:0038001 |
1 |
0.982
|
Fly |
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.982
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
29 |
0.981
|
|
|
regulation of terminal button organization
|
GO:2000331 |
1 |
0.981
|
Fly |
|
defense response to other organism
|
GO:0098542 |
197 |
0.980
|
Worm Fly |
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.980
|
|
|
lipid oxidation
|
GO:0034440 |
29 |
0.979
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.979
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.977
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.973
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.972
|
Human Fly |
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.971
|
|
|
dna replication
|
GO:0006260 |
52 |
0.971
|
Yeast |
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.968
|
Fly |
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.967
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.966
|
|
|
regulation of dna replication
|
GO:0006275 |
17 |
0.964
|
Yeast |
|
positive regulation of determination of dorsal identity
|
GO:2000017 |
2 |
0.962
|
Mouse |
|
response to oxidative stress
|
GO:0006979 |
123 |
0.957
|
Mouse Worm Fly |
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.957
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.956
|
Worm Fly |
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.954
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.951
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.951
|
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
8 |
0.950
|
Yeast |
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.948
|
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
8 |
0.948
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.946
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.946
|
Fly |
|
regulation of determination of dorsal identity
|
GO:2000015 |
3 |
0.945
|
Mouse |
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.945
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.944
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.939
|
Yeast |
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.938
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.937
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.933
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.933
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.931
|
Fly |
|
cellular response to lipid
|
GO:0071396 |
145 |
0.921
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.921
|
|
|
terminal button organization
|
GO:0072553 |
3 |
0.920
|
Fly |
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.920
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
19 |
0.918
|
Fly |
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.918
|
Mouse |
|
connective tissue development
|
GO:0061448 |
179 |
0.918
|
|
|
wound healing
|
GO:0042060 |
157 |
0.916
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.916
|
Worm Fly |
|
negative regulation of jun kinase activity
|
GO:0043508 |
9 |
0.914
|
|
|
cellular response to osmotic stress
|
GO:0071470 |
7 |
0.912
|
Yeast |
|
positive regulation of syncytium formation by plasma membrane fusion
|
GO:0060143 |
17 |
0.911
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.905
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.905
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.905
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.900
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.898
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.897
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
19 |
0.893
|
Fly |
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.892
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.876
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.875
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.875
|
Fly |
|
response to heat
|
GO:0009408 |
27 |
0.873
|
Yeast Fly |
|
syncytium formation
|
GO:0006949 |
43 |
0.871
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.869
|
Mouse Worm Fly |
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.869
|
|
|
response to muramyl dipeptide
|
GO:0032495 |
9 |
0.867
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
32 |
0.863
|
Mouse Fly |
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.863
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.861
|
Human Fly |
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.856
|
Mouse Fly |
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.853
|
Yeast |
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.853
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.842
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.841
|
Mouse Fly |
|
regulation of cell size
|
GO:0008361 |
72 |
0.839
|
Fly |
|
intra s dna damage checkpoint
|
GO:0031573 |
4 |
0.839
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.837
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.835
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.833
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.826
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
5 |
0.820
|
Mouse |
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.817
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.813
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.812
|
Human Yeast |
|
determination of dorsal identity
|
GO:0048263 |
5 |
0.805
|
Mouse |
|
muscle tissue development
|
GO:0060537 |
308 |
0.801
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.801
|
|
|
skeletal muscle tissue regeneration
|
GO:0043403 |
20 |
0.795
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.795
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.795
|
Fly |
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.794
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.792
|
Fly |
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.780
|
|
|
cellular response to metal ion
|
GO:0071248 |
31 |
0.775
|
Fly |
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.773
|
|
|
dna dependent dna replication
|
GO:0006261 |
24 |
0.772
|
Yeast |
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.771
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.768
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.767
|
Mouse |
|
cartilage development
|
GO:0051216 |
140 |
0.764
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.761
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.754
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.750
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.726
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.722
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.721
|
|
|
tissue regeneration
|
GO:0042246 |
22 |
0.717
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.715
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.714
|
|
|
cellular senescence
|
GO:0090398 |
11 |
0.713
|
Human |
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.712
|
Human |
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.712
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.705
|
|
|
cell aggregation
|
GO:0098743 |
18 |
0.698
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.691
|
Fly |
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.687
|
Fly |
|
protein localization to organelle
|
GO:0033365 |
185 |
0.687
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.686
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.681
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.675
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.673
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.668
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.665
|
|
|
cell aging
|
GO:0007569 |
35 |
0.665
|
Human |
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.663
|
Fly |
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.663
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.658
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.657
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.654
|
Mouse Fly |
|
positive regulation of myotube differentiation
|
GO:0010831 |
24 |
0.653
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.649
|
Mouse |
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.648
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.645
|
Fly |
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.644
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.644
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.636
|
|
|
ossification
|
GO:0001503 |
216 |
0.630
|
Mouse |
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.629
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.626
|
Fly |
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.623
|
|
|
regionalization
|
GO:0003002 |
337 |
0.622
|
Mouse |
|
protein targeting
|
GO:0006605 |
143 |
0.613
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.606
|
Fly |
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.606
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.605
|
Mouse |
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.604
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.603
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.603
|
Fly |
|
myoblast differentiation
|
GO:0045445 |
52 |
0.592
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.589
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
26 |
0.588
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.585
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.581
|
Rat |
|
cytokine production
|
GO:0001816 |
319 |
0.576
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.574
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.571
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.563
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.562
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.561
|
|
|
positive regulation of cell size
|
GO:0045793 |
5 |
0.558
|
Fly |
|
3 utr mediated mrna stabilization
|
GO:0070935 |
2 |
0.543
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.542
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
35 |
0.539
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.527
|
|
|
autophagy
|
GO:0006914 |
45 |
0.523
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.518
|
|
|
regulation of tor signaling
|
GO:0032006 |
17 |
0.509
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.507
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.502
|
Fly |
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.496
|
Fly |
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.489
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.483
|
Worm |
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.482
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.472
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.472
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.471
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.465
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.463
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.458
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.448
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.447
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.444
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.440
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.438
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.434
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.433
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.431
|
Fly |
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.431
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.431
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.428
|
Mouse |
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.412
|
|
|
epiboly
|
GO:0090504 |
8 |
0.402
|
|
|
placenta development
|
GO:0001890 |
140 |
0.401
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.397
|
|
|
negative regulation of humoral immune response
|
GO:0002921 |
6 |
0.392
|
Fly |
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.388
|
Fly |
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.381
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.381
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.377
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.376
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.374
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.372
|
|
|
determination of adult lifespan
|
GO:0008340 |
11 |
0.371
|
Fly |
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.365
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.364
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.356
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.352
|
Fly |
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.348
|
Fly |
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.347
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.338
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.329
|
Human |
|
regulation of cell motility
|
GO:2000145 |
236 |
0.326
|
|
|
regeneration
|
GO:0031099 |
38 |
0.322
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.319
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.319
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.315
|
|
|
axon regeneration
|
GO:0031103 |
12 |
0.313
|
|
|
negative regulation of tor signaling
|
GO:0032007 |
13 |
0.313
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.312
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
39 |
0.311
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
27 |
0.306
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.303
|
Fly |
|
pigment metabolic process
|
GO:0042440 |
32 |
0.303
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.303
|
|
|
defense response to fungus
|
GO:0050832 |
12 |
0.300
|
Fly |
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.298
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.290
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.290
|
Yeast |
|
camera type eye development
|
GO:0043010 |
266 |
0.274
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.272
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.263
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.263
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.262
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.261
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.261
|
|
|
anion transport
|
GO:0006820 |
177 |
0.260
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.260
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.256
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.253
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.245
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.245
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.241
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.240
|
|
|
positive regulation of autophagy
|
GO:0010508 |
9 |
0.239
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.232
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.232
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
9 |
0.230
|
Yeast |
|
antimicrobial humoral response
|
GO:0019730 |
11 |
0.227
|
Fly |
|
ectodermal digestive tract development
|
GO:0007439 |
1 |
0.223
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.221
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.219
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.217
|
|
|
stress induced premature senescence
|
GO:0090400 |
2 |
0.217
|
Human |
|
positive regulation of macrophage derived foam cell differentiation
|
GO:0010744 |
4 |
0.216
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.211
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.210
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.209
|
|
|
tor signaling
|
GO:0031929 |
21 |
0.208
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.207
|
|
|
action potential
|
GO:0001508 |
78 |
0.207
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.204
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.204
|
Human |
|
gland development
|
GO:0048732 |
330 |
0.202
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.198
|
Worm |
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.197
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.195
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.195
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.193
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.191
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.191
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.188
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.187
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.187
|
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.184
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.184
|
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.183
|
|
|
response to cadmium ion
|
GO:0046686 |
8 |
0.181
|
Mouse Fly |
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.181
|
|
|
response to drug
|
GO:0042493 |
75 |
0.179
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.178
|
Fly |
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.177
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.176
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.176
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.175
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.171
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.170
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.170
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.166
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.165
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.164
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.159
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.159
|
|
|
cellular response to cadmium ion
|
GO:0071276 |
3 |
0.159
|
Fly |
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.155
|
Worm |
|
necrotic cell death
|
GO:0070265 |
30 |
0.154
|
Mouse |
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.154
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.153
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.153
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.152
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.151
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.150
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.149
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.149
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.148
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.147
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.146
|
Human |
|
neuron projection regeneration
|
GO:0031102 |
14 |
0.146
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.145
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.145
|
|
|
male courtship behavior
|
GO:0008049 |
2 |
0.143
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.142
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.142
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.138
|
|
|
regulation of engulfment of apoptotic cell
|
GO:1901074 |
2 |
0.138
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.137
|
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.137
|
|
|
pinocytosis
|
GO:0006907 |
6 |
0.137
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.135
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.134
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.133
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.132
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.132
|
|
|
positive regulation of fatty acid biosynthetic process
|
GO:0045723 |
3 |
0.130
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.130
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.128
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.127
|
Fly |
|
mrna stabilization
|
GO:0048255 |
9 |
0.126
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.126
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.125
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.124
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.124
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.123
|
|
|
regulation of fatty acid metabolic process
|
GO:0019217 |
28 |
0.120
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.119
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.118
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.117
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.117
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.117
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.116
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.115
|
|
|
response to uv
|
GO:0009411 |
44 |
0.114
|
|
|
placenta blood vessel development
|
GO:0060674 |
31 |
0.114
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.113
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.113
|
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.112
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.112
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.112
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.111
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.111
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.110
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.109
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.108
|
Fly |
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.107
|
|
|
macroautophagy
|
GO:0016236 |
21 |
0.107
|
|
|
mitochondrial transport
|
GO:0006839 |
36 |
0.107
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.106
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.105
|
|
|
rna stabilization
|
GO:0043489 |
9 |
0.105
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.103
|
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.103
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.102
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.101
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.101
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.100
|
|
|
regulation of mrna stability
|
GO:0043488 |
23 |
0.100
|
|
|
regulation of transforming growth factor beta2 production
|
GO:0032909 |
2 |
0.099
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.099
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.099
|
|
|
liver development
|
GO:0001889 |
66 |
0.098
|
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.097
|
|
|
monocyte differentiation
|
GO:0030224 |
9 |
0.096
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.096
|
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.095
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.095
|
|
|
lung development
|
GO:0030324 |
164 |
0.094
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.094
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
44 |
0.093
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.093
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.092
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.092
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.091
|
Fly |
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.091
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.090
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.089
|
|
|
cellular response to vascular endothelial growth factor stimulus
|
GO:0035924 |
11 |
0.089
|
Human |
|
neuron death
|
GO:0070997 |
154 |
0.088
|
|
|
multicellular organismal aging
|
GO:0010259 |
24 |
0.088
|
Fly |
|
regulation of tube size
|
GO:0035150 |
57 |
0.087
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.087
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.086
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.085
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.085
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.084
|
|
|
heart process
|
GO:0003015 |
94 |
0.084
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.083
|
|
|
regulation of keratinocyte differentiation
|
GO:0045616 |
11 |
0.083
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
34 |
0.082
|
|
|
translational initiation
|
GO:0006413 |
24 |
0.082
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.082
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.082
|
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
8 |
0.081
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.081
|
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.080
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.080
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.080
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.080
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.080
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.079
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.079
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
60 |
0.079
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.078
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.078
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.077
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.077
|
|
|
embryonic digestive tract development
|
GO:0048566 |
27 |
0.076
|
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.076
|
|
|
regulation of stem cell maintenance
|
GO:2000036 |
17 |
0.076
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.076
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.075
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.075
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
34 |
0.075
|
|
|
determination of digestive tract left right asymmetry
|
GO:0071907 |
1 |
0.075
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.074
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.074
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.073
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.073
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.073
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.073
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.073
|
Yeast Fly |
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.072
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.072
|
|
|
fibroblast migration
|
GO:0010761 |
21 |
0.072
|
|
|
regulation of fatty acid biosynthetic process
|
GO:0042304 |
12 |
0.070
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.070
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
12 |
0.069
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.068
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.067
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.066
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
34 |
0.065
|
|
|
post embryonic retina morphogenesis in camera type eye
|
GO:0060060 |
3 |
0.065
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.065
|
|
|
mitochondrial membrane organization
|
GO:0007006 |
26 |
0.065
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.064
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.064
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.064
|
|
|
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072364 |
7 |
0.064
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.063
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
6 |
0.063
|
|
|
mitochondrial outer membrane permeabilization involved in programmed cell death
|
GO:1902686 |
11 |
0.063
|
|
|
apoptotic cell clearance
|
GO:0043277 |
17 |
0.063
|
|
|
vascular endothelial growth factor receptor signaling pathway
|
GO:0048010 |
24 |
0.063
|
Human |
|
forebrain development
|
GO:0030900 |
302 |
0.063
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.063
|
|
|
cellular response to light stimulus
|
GO:0071482 |
19 |
0.062
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.062
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.062
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.062
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.062
|
|