|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.961
|
Worm Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.958
|
Worm Fly |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.683
|
Yeast |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.653
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.637
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.630
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.599
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.589
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.586
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.482
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.469
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.467
|
|
|
|
cellular response to arsenic containing substance
|
GO:0071243 |
4 |
0.451
|
Fly |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.430
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.420
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.420
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.416
|
|
|
|
regulation of transposition
|
GO:0010528 |
2 |
0.411
|
Yeast |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.404
|
|
|
|
adherens junction maintenance
|
GO:0034334 |
1 |
0.402
|
Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.393
|
Yeast Worm |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.390
|
Human |
|
|
establishment of melanosome localization
|
GO:0032401 |
11 |
0.382
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.381
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.373
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.360
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.333
|
Human Mouse Rat Worm |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.330
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.323
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.317
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.314
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.301
|
Fly |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.294
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.293
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.285
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.279
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.278
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.276
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.276
|
Worm |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.269
|
Yeast Rat |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.268
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.265
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.254
|
Fly |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.254
|
Yeast |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.243
|
Human Yeast Fly |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.243
|
Yeast |
|
|
adult behavior
|
GO:0030534 |
135 |
0.242
|
Fly |
|
|
microtubule based process
|
GO:0007017 |
236 |
0.241
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.240
|
|
|
|
phototransduction
|
GO:0007602 |
17 |
0.240
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.240
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.239
|
Yeast Rat |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.237
|
Mouse Rat Worm |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.236
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.232
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.229
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.227
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.225
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.222
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.222
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.215
|
|
|
|
establishment of endothelial blood brain barrier
|
GO:0014045 |
3 |
0.215
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.211
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.208
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.208
|
|
|
|
pigmentation
|
GO:0043473 |
71 |
0.206
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.205
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.203
|
Mouse Rat Worm |
|
|
protein targeting
|
GO:0006605 |
143 |
0.202
|
Rat |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.202
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.200
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.199
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.195
|
Fly |
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.193
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.192
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.192
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.188
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.181
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.180
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.179
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.179
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.177
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.176
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.175
|
Yeast |
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.173
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.170
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.169
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.169
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.168
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.166
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.165
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.165
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.162
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.161
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.159
|
Fly |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.158
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.157
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.150
|
Fly |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.146
|
Mouse |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.145
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.143
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.140
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.139
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.139
|
Yeast |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.139
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.139
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.138
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.137
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.136
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.136
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.136
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.136
|
Yeast |
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.133
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.133
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.132
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.131
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.130
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.130
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.129
|
Worm Fly |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.128
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.127
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.127
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.126
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
15 |
0.126
|
Worm |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.125
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.125
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.124
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.123
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.123
|
Worm |
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.121
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.121
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.120
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.119
|
Yeast Worm |
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.119
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.119
|
Human |
|
|
glucose transport
|
GO:0015758 |
56 |
0.118
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.118
|
Rat |
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.118
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.117
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.117
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.116
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.116
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.115
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.115
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.115
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.112
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.111
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.110
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.108
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.108
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.105
|
Rat |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.104
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.104
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.104
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.104
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.104
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.103
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.103
|
Human Mouse |
|
|
autophagy
|
GO:0006914 |
45 |
0.103
|
Fly |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.102
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.101
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.101
|
Fly |
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.101
|
|
|
|
negative regulation of binding
|
GO:0051100 |
39 |
0.098
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.098
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.098
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.097
|
|
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.097
|
Fly |
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.096
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.096
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.095
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
34 |
0.095
|
Worm |
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.095
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.095
|
Worm |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.094
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.094
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.094
|
Fly |
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.094
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.093
|
Rat |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.093
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.093
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.092
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.091
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.090
|
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
51 |
0.090
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.089
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.089
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.088
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.088
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.087
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.087
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.087
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.087
|
Rat |
|
|
cell cycle switching mitotic to meiotic cell cycle
|
GO:0051728 |
1 |
0.086
|
Worm |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.086
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.086
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.086
|
|
|
|
glucose import
|
GO:0046323 |
32 |
0.085
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.085
|
|
|
|
oocyte maturation
|
GO:0001556 |
18 |
0.085
|
Worm |
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.084
|
|
|
|
insulin secretion involved in cellular response to glucose stimulus
|
GO:0035773 |
36 |
0.084
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.083
|
|
|
|
cellular component maintenance
|
GO:0043954 |
11 |
0.083
|
Fly |
|
|
cartilage development
|
GO:0051216 |
140 |
0.083
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.083
|
Human |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.082
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.081
|
Worm |
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.081
|
|
|
|
labyrinthine layer blood vessel development
|
GO:0060716 |
21 |
0.081
|
Mouse |
|
|
apical junction assembly
|
GO:0043297 |
15 |
0.080
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.080
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.080
|
|
|
|
long term memory
|
GO:0007616 |
15 |
0.079
|
|
|
|
macroautophagy
|
GO:0016236 |
21 |
0.079
|
Fly |
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.079
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.078
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.078
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.078
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.077
|
Yeast |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.077
|
Human Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.077
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.076
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.076
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.075
|
Fly |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.075
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.074
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.074
|
Mouse |
|
|
regulation of killing of cells of other organism
|
GO:0051709 |
4 |
0.072
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.072
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.072
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.072
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.071
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.071
|
Rat |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.070
|
|
|
|
regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061178 |
31 |
0.070
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.069
|
Human Fly |
|
|
response to epidermal growth factor
|
GO:0070849 |
4 |
0.069
|
Human |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.069
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.068
|
Mouse |
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.068
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.068
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.068
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.067
|
Fly |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.067
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.067
|
Rat |
|
|
protein import
|
GO:0017038 |
101 |
0.067
|
Rat |
|
|
protein processing
|
GO:0016485 |
163 |
0.066
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.066
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.066
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.065
|
Yeast Rat |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.064
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.064
|
Yeast Rat |
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.064
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.064
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.063
|
Fly |
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.063
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.063
|
Fly |
|
|
melanosome localization
|
GO:0032400 |
12 |
0.063
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.063
|
|
|
|
vesicle fusion
|
GO:0006906 |
16 |
0.063
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.063
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.063
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.062
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.062
|
Fly |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.062
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.062
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.062
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.061
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.061
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.061
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.060
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.060
|
Fly |
|
|
cell maturation
|
GO:0048469 |
127 |
0.060
|
Worm |
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.059
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.059
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.059
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.059
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.059
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.059
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.058
|
Fly |
|
|
connective tissue development
|
GO:0061448 |
179 |
0.058
|
|
|
|
disruption of cells of other organism involved in symbiotic interaction
|
GO:0051818 |
13 |
0.058
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.058
|
Rat |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.058
|
Yeast |
|
|
regulation of vesicle fusion
|
GO:0031338 |
6 |
0.057
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.057
|
Yeast |
|
|
organelle localization
|
GO:0051640 |
179 |
0.057
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.057
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.056
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.056
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.055
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.055
|
|
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.055
|
Fly |
|
|
disruption of cells of other organism
|
GO:0044364 |
13 |
0.055
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.055
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.054
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.054
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.054
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
47 |
0.054
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.054
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.054
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.054
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.054
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.053
|
|
|
|
modulation by virus of host process
|
GO:0019054 |
2 |
0.052
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.052
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.052
|
Mouse |
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.051
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.051
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.051
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.051
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.051
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.051
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.051
|
|
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
4 |
0.051
|
Yeast |
|
|
cellular glucose homeostasis
|
GO:0001678 |
52 |
0.051
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.050
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.050
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.050
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.050
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.050
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.050
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.050
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.050
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.049
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.049
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.049
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.049
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.049
|
|
|
|
response to arsenic containing substance
|
GO:0046685 |
5 |
0.048
|
Fly |
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.048
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.048
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.048
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.048
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.048
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.048
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.047
|
|
|
|
killing of cells in other organism involved in symbiotic interaction
|
GO:0051883 |
13 |
0.047
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.047
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.046
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
38 |
0.046
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.046
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.046
|
Fly |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.046
|
Mouse |
|
|
hormone secretion
|
GO:0046879 |
128 |
0.046
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.045
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.045
|
Yeast |
|
|
pyrimidine containing compound metabolic process
|
GO:0072527 |
11 |
0.045
|
Mouse |
|
|
positive regulation of insulin secretion
|
GO:0032024 |
26 |
0.045
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.045
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.044
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.044
|
Fly |
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.044
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.044
|
Fly |
|
|
gland development
|
GO:0048732 |
330 |
0.044
|
Mouse |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.044
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.044
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.043
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.043
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.043
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.043
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.043
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.043
|
Human |
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
36 |
0.042
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.042
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.042
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.042
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.042
|
|
|
|
synaptic transmission gabaergic
|
GO:0051932 |
19 |
0.042
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.042
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.042
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.042
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.041
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.041
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.041
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
16 |
0.041
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.041
|
Rat |
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.040
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.040
|
Zebrafish |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.040
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.040
|
Human |
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.040
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.040
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.040
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.040
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.039
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.039
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.039
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.039
|
|
|
|
cellular response to glucose stimulus
|
GO:0071333 |
45 |
0.039
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.039
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.039
|
Fly |
|
|
positive regulation of membrane potential
|
GO:0045838 |
15 |
0.038
|
|
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.038
|
|
|
|
g protein coupled acetylcholine receptor signaling pathway
|
GO:0007213 |
4 |
0.038
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.038
|
|
|
|
cellular response to hexose stimulus
|
GO:0071331 |
47 |
0.038
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.038
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.038
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.037
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.037
|
Yeast |
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.037
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.037
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.037
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.037
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.037
|
Fly |
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.036
|
|
|
|
mitochondrial membrane organization
|
GO:0007006 |
26 |
0.036
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.036
|
Fly |
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.036
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
34 |
0.036
|
|
|
|
pigment granule localization
|
GO:0051875 |
13 |
0.036
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.036
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.036
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
18 |
0.036
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.035
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.035
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.035
|
Human Fly |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.035
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.035
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.035
|
Yeast |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.035
|
|
|
|
organelle fusion
|
GO:0048284 |
28 |
0.035
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.035
|
|
|
|
placenta blood vessel development
|
GO:0060674 |
31 |
0.034
|
Mouse |
|
|
negative regulation of transposition
|
GO:0010529 |
2 |
0.034
|
Yeast |
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.034
|
Fly |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.034
|
|
|
|
cellular response to osmotic stress
|
GO:0071470 |
7 |
0.034
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.034
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.034
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
22 |
0.034
|
|
|
|
killing of cells of other organism
|
GO:0031640 |
13 |
0.034
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.034
|
|
|
|
regulation of glucose transport
|
GO:0010827 |
32 |
0.034
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.034
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.034
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.033
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.033
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.033
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.033
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
3 |
0.033
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.033
|
Human Fly |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.033
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.033
|
Mouse |
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.033
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.033
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.033
|
Mouse |
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.033
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.033
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.032
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.032
|
|
|
|
reproductive behavior
|
GO:0019098 |
32 |
0.032
|
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
33 |
0.032
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.032
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.032
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.032
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
30 |
0.032
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.031
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.031
|
Fly |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.031
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.031
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.031
|
Human |
|
|
regulation of protein depolymerization
|
GO:1901879 |
26 |
0.031
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.031
|
Yeast |
|
|
female gamete generation
|
GO:0007292 |
74 |
0.030
|
Worm |
|
|
ossification
|
GO:0001503 |
216 |
0.030
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.030
|
Worm |
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.030
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.030
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.030
|
Mouse |
|
|
cellular response to salt stress
|
GO:0071472 |
1 |
0.030
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.030
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.030
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.029
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.029
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.029
|
Fly |
|
|
actin filament organization
|
GO:0007015 |
113 |
0.029
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.029
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.029
|
|
|
|
regulation of arp2 3 complex mediated actin nucleation
|
GO:0034315 |
1 |
0.029
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
13 |
0.028
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.028
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.028
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.028
|
Human Yeast |
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.028
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
27 |
0.028
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.028
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.028
|
Fly |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.028
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.027
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.027
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.027
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.027
|
Worm |
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.027
|
|
