Mus musculus

116 known processes

Mapk8ip1

mitogen-activated protein kinase 8 interacting protein 1

(Aliases: JIP-1,Prkm8ip,Skip,Jip1,mjip-2a,IB1)

Mapk8ip1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
sterol metabolic process GO:0016125 58 0.989
regulation of protein kinase activity GO:0045859 232 0.980
Rat
activation of mapkk activity GO:0000186 15 0.975
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.969
regulation of phospholipase a2 activity GO:0032429 3 0.952
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.936
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.934
cholesterol metabolic process GO:0008203 56 0.929
negative regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000160 1 0.924
regulation of transferase activity GO:0051338 263 0.909
Rat
non canonical wnt signaling pathway GO:0035567 33 0.905
intracellular cholesterol transport GO:0032367 3 0.900
formation of radial glial scaffolds GO:0021943 4 0.896
establishment of planar polarity GO:0001736 28 0.894
intracellular sterol transport GO:0032366 3 0.876
positive regulation of kinase activity GO:0033674 155 0.863
positive regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000060 8 0.861
regulation of establishment of planar polarity GO:0090175 28 0.859
negative regulation of smooth muscle cell migration GO:0014912 2 0.859
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000162 1 0.844
negative regulation of cholesterol transport GO:0032375 4 0.841
positive regulation of protein kinase activity GO:0045860 144 0.839
plasma lipoprotein particle clearance GO:0034381 13 0.838
synapse organization GO:0050808 125 0.838
Fly
regulation of mapk cascade GO:0043408 248 0.826
positive regulation of protein phosphorylation GO:0001934 242 0.819
negative regulation of platelet derived growth factor receptor beta signaling pathway GO:2000587 2 0.810
protein localization to membrane GO:0072657 108 0.801
establishment of protein localization to organelle GO:0072594 118 0.794
axonogenesis GO:0007409 274 0.792
establishment of tissue polarity GO:0007164 28 0.790
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.777
regulation of kinase activity GO:0043549 249 0.767
Rat
mapk cascade GO:0000165 281 0.758
regulation of plasma lipoprotein particle levels GO:0097006 23 0.755
canonical wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development GO:0061310 1 0.754
positive regulation of cell death GO:0010942 224 0.745
receptor mediated endocytosis of low density lipoprotein particle involved in cholesterol transport GO:0090118 1 0.727
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.727
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000149 1 0.726
morphogenesis of a polarized epithelium GO:0001738 37 0.726
intracellular lipid transport GO:0032365 3 0.706
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000164 1 0.700
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.688
canonical wnt signaling pathway involved in neural crest cell differentiation GO:0044335 1 0.685
positive regulation of protein modification process GO:0031401 299 0.682
synaptic growth at neuromuscular junction GO:0051124 6 0.677
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.671
negative regulation of planar cell polarity pathway involved in neural tube closure GO:2000168 1 0.671
positive regulation of mapk cascade GO:0043410 170 0.669
extracellular matrix cell signaling GO:0035426 5 0.665
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.663
regulation of cellular amine metabolic process GO:0033238 20 0.661
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.653
alcohol metabolic process GO:0006066 116 0.650
regulation of cellular amino acid metabolic process GO:0006521 5 0.646
positive regulation of sterol transport GO:0032373 9 0.642
regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:2000150 1 0.638
cytoskeleton dependent intracellular transport GO:0030705 50 0.638
Fly
peptidyl amino acid modification GO:0018193 336 0.635
activation of mapkkk activity GO:0000185 1 0.615
cellular amino acid metabolic process GO:0006520 103 0.614
regulation of platelet derived growth factor receptor beta signaling pathway GO:2000586 2 0.606
presynaptic membrane organization GO:0097090 8 0.605
presynaptic membrane assembly GO:0097105 7 0.601
regulation of planar cell polarity pathway involved in neural tube closure GO:2000167 1 0.599
membrane organization GO:0061024 245 0.598
regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000161 1 0.595
axon cargo transport GO:0008088 33 0.590
Fly
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 10 0.581
negative regulation of cell development GO:0010721 169 0.578
synapse assembly GO:0007416 56 0.573
regulation of cellular ketone metabolic process GO:0010565 66 0.571
regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000159 1 0.571
negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:2000151 1 0.562
hindbrain radial glia guided cell migration GO:0021932 12 0.561
negative regulation of platelet derived growth factor receptor signaling pathway GO:0010642 7 0.558
postsynaptic membrane assembly GO:0097104 6 0.556
epidermal growth factor receptor signaling pathway GO:0007173 28 0.547
regulation of non canonical wnt signaling pathway GO:2000050 12 0.542
negative regulation of neuron projection development GO:0010977 50 0.538
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.535
membrane biogenesis GO:0044091 12 0.528
developmental growth involved in morphogenesis GO:0060560 138 0.524
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.521
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.511
positive regulation of transferase activity GO:0051347 167 0.510
cholesterol transport GO:0030301 38 0.510
regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000165 1 0.507
protein catabolic process GO:0030163 221 0.502
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.502
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.491
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.490
negative regulation of neuron differentiation GO:0045665 101 0.490
regulation of binding GO:0051098 111 0.486
gastrulation GO:0007369 116 0.484
regulation of presynaptic membrane organization GO:1901629 3 0.471
regulation of neuron differentiation GO:0045664 281 0.469
appendage development GO:0048736 166 0.462
positive regulation of apoptotic process GO:0043065 217 0.457
regulation of lipase activity GO:0060191 15 0.451
heart morphogenesis GO:0003007 178 0.451
positive regulation of proteolysis GO:0045862 85 0.451
peptidyl tyrosine modification GO:0018212 145 0.448
lipid transport GO:0006869 98 0.446
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.442
embryonic retina morphogenesis in camera type eye GO:0060059 7 0.441
digestive tract morphogenesis GO:0048546 147 0.439
protein targeting GO:0006605 143 0.438
positive regulation of cholesterol transport GO:0032376 9 0.433
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.428
midbrain hindbrain boundary development GO:0030917 9 0.428
cellular amine metabolic process GO:0044106 44 0.427
actin cytoskeleton organization GO:0030036 220 0.425
synaptic vesicle localization GO:0097479 59 0.418
Fly
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.416
peptidyl tyrosine phosphorylation GO:0018108 143 0.416
negative regulation of sterol transport GO:0032372 4 0.410
cell proliferation in hindbrain GO:0021534 10 0.407
negative regulation of cellular component organization GO:0051129 194 0.406
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 9 0.406
muscle tissue development GO:0060537 308 0.402
steroid metabolic process GO:0008202 119 0.400
sterol transport GO:0015918 38 0.400
protein localization to organelle GO:0033365 185 0.391
macromolecule catabolic process GO:0009057 281 0.379
positive regulation of cerebellar granule cell precursor proliferation GO:0021940 10 0.379
axis elongation involved in somitogenesis GO:0090245 4 0.376
protein import into nucleus GO:0006606 95 0.371
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 14 0.366
microtubule based movement GO:0007018 84 0.365
Fly
endodermal cell fate specification GO:0001714 4 0.365
negative regulation of cardiac muscle tissue development GO:0055026 8 0.365
microtubule based transport GO:0010970 50 0.365
Fly
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.364
positive regulation of cellular protein catabolic process GO:1903364 34 0.363
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.363
genitalia morphogenesis GO:0035112 11 0.362
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.357
intracellular protein transport GO:0006886 204 0.357
positive regulation of protein ubiquitination GO:0031398 27 0.357
dendrite development GO:0016358 115 0.354
Mouse
post anal tail morphogenesis GO:0036342 23 0.351
regulation of cardiac muscle tissue development GO:0055024 31 0.347
trachea cartilage morphogenesis GO:0060535 4 0.346
skeletal muscle acetylcholine gated channel clustering GO:0071340 7 0.342
regulation of sterol transport GO:0032371 17 0.342
mammary placode formation GO:0060596 4 0.334
osteoblast development GO:0002076 17 0.334
response to amino acid GO:0043200 37 0.333
cardiac right atrium morphogenesis GO:0003213 3 0.331
endomembrane system organization GO:0010256 147 0.329
positive regulation of lipid transport GO:0032370 22 0.327
external genitalia morphogenesis GO:0035261 1 0.317
regulation of cellular catabolic process GO:0031329 242 0.314
erbb signaling pathway GO:0038127 32 0.314
wnt signaling pathway GO:0016055 188 0.311
cytoplasmic transport GO:0016482 234 0.310
forebrain radial glial cell differentiation GO:0021861 4 0.310
establishment of organelle localization GO:0051656 122 0.310
Fly
negative regulation of cell projection organization GO:0031345 56 0.309
amine metabolic process GO:0009308 45 0.302
regulation of neuron projection development GO:0010975 169 0.302
ubiquitin dependent protein catabolic process GO:0006511 129 0.299
neuroblast division GO:0055057 10 0.296
epithelial tube formation GO:0072175 130 0.292
nuclear transport GO:0051169 139 0.291
peptide transport GO:0015833 133 0.288
rna 3 end processing GO:0031123 20 0.287
primary neural tube formation GO:0014020 95 0.286
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.285
regulation of cardiac chamber morphogenesis GO:1901219 2 0.284
midbrain development GO:0030901 35 0.279
cerebellum morphogenesis GO:0021587 42 0.278
limb morphogenesis GO:0035108 149 0.277
appendage morphogenesis GO:0035107 149 0.275
regulation of receptor activity GO:0010469 41 0.274
Mouse
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.271
angiogenesis GO:0001525 201 0.271
protein ubiquitination GO:0016567 171 0.270
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.267
negative regulation of epithelial cell proliferation GO:0050680 64 0.262
cardiac muscle tissue development GO:0048738 130 0.261
retina vasculature morphogenesis in camera type eye GO:0061299 10 0.259
positive regulation of cholesterol efflux GO:0010875 9 0.259
postsynaptic membrane organization GO:0001941 18 0.257
respiratory system development GO:0060541 190 0.257
tube formation GO:0035148 140 0.255
cellular protein catabolic process GO:0044257 155 0.255
regulation of cell motility GO:2000145 236 0.254
hindlimb morphogenesis GO:0035137 42 0.254
convergent extension GO:0060026 14 0.252
regulation of cerebellar granule cell precursor proliferation GO:0021936 12 0.252
cerebellar granule cell precursor proliferation GO:0021930 10 0.250
cell proliferation in external granule layer GO:0021924 10 0.249
cellular glucose homeostasis GO:0001678 52 0.248
cerebral cortex cell migration GO:0021795 44 0.246
mrna 3 end processing GO:0031124 16 0.243
lipid localization GO:0010876 126 0.243
positive regulation of nervous system development GO:0051962 221 0.242
retina development in camera type eye GO:0060041 119 0.233
cardiac atrium development GO:0003230 24 0.232
negative regulation of nervous system development GO:0051961 156 0.231
response to folic acid GO:0051593 2 0.230
cellular ketone metabolic process GO:0042180 84 0.228
protein modification by small protein conjugation or removal GO:0070647 207 0.224
regulation of tissue remodeling GO:0034103 38 0.223
membrane assembly GO:0071709 12 0.222
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.221
negative regulation of cell migration GO:0030336 59 0.218
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.216
regulation of cell projection organization GO:0031344 206 0.216
positive regulation of programmed cell death GO:0043068 218 0.212
regulation of actin cytoskeleton organization GO:0032956 84 0.212
negative regulation of non canonical wnt signaling pathway GO:2000051 5 0.211
digestive system development GO:0055123 200 0.211
regulation of actin filament based process GO:0032970 99 0.210
negative regulation of cell motility GO:2000146 61 0.209
low density lipoprotein particle clearance GO:0034383 8 0.208
regulation of muscle tissue development GO:1901861 97 0.208
regulation of cellular protein catabolic process GO:1903362 61 0.208
microtubule based process GO:0007017 236 0.208
Fly
limb development GO:0060173 166 0.207
smooth muscle cell migration GO:0014909 10 0.205
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.205
organic hydroxy compound transport GO:0015850 93 0.205
gliogenesis GO:0042063 141 0.203
regulation of cell migration GO:0030334 219 0.200
embryonic digit morphogenesis GO:0042733 56 0.200
endocytosis GO:0006897 168 0.198
cartilage development GO:0051216 140 0.198
nuclear import GO:0051170 95 0.197
cardiac chamber development GO:0003205 108 0.196
developmental cell growth GO:0048588 84 0.194
neural tube patterning GO:0021532 43 0.193
digestive tract development GO:0048565 190 0.192
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.191
regulation of cytoskeleton organization GO:0051493 122 0.190
hindbrain development GO:0030902 128 0.187
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.186
amide transport GO:0042886 138 0.184
embryonic limb morphogenesis GO:0030326 126 0.183
forebrain neuroblast division GO:0021873 9 0.183
modification dependent macromolecule catabolic process GO:0043632 133 0.182
response to acid chemical GO:0001101 111 0.181
regulation of cholesterol transport GO:0032374 17 0.181
skeletal system morphogenesis GO:0048705 203 0.179
negative regulation of embryonic development GO:0045992 22 0.178
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.177
bone morphogenesis GO:0060349 78 0.177
embryonic epithelial tube formation GO:0001838 130 0.177
regulation of osteoblast proliferation GO:0033688 15 0.176
neural precursor cell proliferation GO:0061351 121 0.175
cellular response to monosaccharide stimulus GO:0071326 47 0.173
tube closure GO:0060606 91 0.172
regulation of apoptotic signaling pathway GO:2001233 197 0.170
establishment of synaptic vesicle localization GO:0097480 57 0.170
Fly
regulation of protein tyrosine kinase activity GO:0061097 17 0.169
mammary gland lobule development GO:0061377 22 0.169
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.168
positive regulation of protein catabolic process GO:0045732 60 0.165
nucleocytoplasmic transport GO:0006913 139 0.164
anion transport GO:0006820 177 0.164
connective tissue development GO:0061448 179 0.164
protein localization to nucleus GO:0034504 121 0.163
striated muscle tissue development GO:0014706 293 0.162
cellular response to carbohydrate stimulus GO:0071322 50 0.160
cardiac septum development GO:0003279 59 0.158
positive regulation of presynaptic membrane organization GO:1901631 1 0.155
establishment of vesicle localization GO:0051650 81 0.155
Fly
neural tube development GO:0021915 160 0.155
response to extracellular stimulus GO:0009991 127 0.153
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.151
embryonic heart tube development GO:0035050 65 0.150
determination of left right symmetry GO:0007368 80 0.148
jnk cascade GO:0007254 72 0.145
regulation of hormone secretion GO:0046883 88 0.144
cell migration in hindbrain GO:0021535 16 0.143
vesicle localization GO:0051648 86 0.143
Fly
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.142
respiratory tube development GO:0030323 167 0.141
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.140
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.140
negative regulation of fat cell differentiation GO:0045599 36 0.140
blood vessel morphogenesis GO:0048514 285 0.140
forebrain cell migration GO:0021885 58 0.139
canonical wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation GO:0061324 2 0.138
neuronal stem cell division GO:0036445 10 0.138
nitrogen compound transport GO:0071705 271 0.134
metencephalon development GO:0022037 89 0.133
single organism nuclear import GO:1902593 95 0.133
forebrain development GO:0030900 302 0.133
regulation of protein serine threonine kinase activity GO:0071900 157 0.133
Rat
somitogenesis GO:0001756 69 0.132
response to organic cyclic compound GO:0014070 198 0.132
regulation of lipid transport GO:0032368 36 0.129
organic hydroxy compound metabolic process GO:1901615 203 0.129
hindbrain morphogenesis GO:0021575 46 0.128
camera type eye development GO:0043010 266 0.127
regulation of cholesterol efflux GO:0010874 13 0.126
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.125
ras protein signal transduction GO:0007265 77 0.124
beta amyloid clearance GO:0097242 2 0.123
organelle localization GO:0051640 179 0.122
Fly
neural tube formation GO:0001841 108 0.122
carbohydrate homeostasis GO:0033500 128 0.121
stem cell proliferation GO:0072089 117 0.121
jak stat cascade GO:0007259 42 0.120
toxin transport GO:1901998 38 0.119
positive regulation of ossification GO:0045778 47 0.119
muscle tissue morphogenesis GO:0060415 53 0.119
regulation of secretion GO:0051046 274 0.119
regulation of protein catabolic process GO:0042176 108 0.116
positive regulation of cellular catabolic process GO:0031331 148 0.116
regulation of smooth muscle cell migration GO:0014910 6 0.116
ionotropic glutamate receptor signaling pathway GO:0035235 29 0.115
Mouse
cell migration involved in gastrulation GO:0042074 13 0.115
pallium development GO:0021543 120 0.115
ribonucleoside metabolic process GO:0009119 245 0.115
regulation of hydrolase activity GO:0051336 246 0.114
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.114
fat cell differentiation GO:0045444 160 0.112
telencephalon development GO:0021537 186 0.111
negative regulation of cholesterol efflux GO:0090370 4 0.111
embryonic hindlimb morphogenesis GO:0035116 32 0.110
telencephalon cell migration GO:0022029 55 0.110
regulation of proteolysis GO:0030162 164 0.107
muscle cell differentiation GO:0042692 261 0.107
small gtpase mediated signal transduction GO:0007264 97 0.107
apoptotic cell clearance GO:0043277 17 0.107
hair follicle development GO:0001942 85 0.106
glycosyl compound catabolic process GO:1901658 206 0.105
regulation of jnk cascade GO:0046328 62 0.105
peptide hormone secretion GO:0030072 109 0.104
cell division GO:0051301 120 0.104
regulation of protein ubiquitination GO:0031396 52 0.103
glial cell differentiation GO:0010001 131 0.103
response to monosaccharide GO:0034284 67 0.102
cellular chemical homeostasis GO:0055082 215 0.101
molting cycle GO:0042303 90 0.101
response to transforming growth factor beta GO:0071559 88 0.100
carbohydrate derivative catabolic process GO:1901136 231 0.100
regulation of organelle organization GO:0033043 289 0.100
rostrocaudal neural tube patterning GO:0021903 12 0.100
ameboidal type cell migration GO:0001667 128 0.099
cholesterol efflux GO:0033344 24 0.099
regulation of homeostatic process GO:0032844 182 0.098
neuroblast proliferation GO:0007405 49 0.098
response to nutrient levels GO:0031667 109 0.098
cellular homeostasis GO:0019725 240 0.098
cellular copper ion homeostasis GO:0006878 8 0.096
positive regulation of homeostatic process GO:0032846 64 0.095
regulation of phospholipase activity GO:0010517 9 0.094
regulation of fat cell differentiation GO:0045598 81 0.094
peptidyl serine phosphorylation GO:0018105 74 0.092
purine containing compound catabolic process GO:0072523 213 0.091
glucose homeostasis GO:0042593 128 0.091
transmembrane transport GO:0055085 412 0.091
Mouse
bone development GO:0060348 120 0.090
retina vasculature development in camera type eye GO:0061298 17 0.090
embryonic appendage morphogenesis GO:0035113 126 0.090
peptide secretion GO:0002790 114 0.089
vitamin metabolic process GO:0006766 23 0.088
positive regulation of bone resorption GO:0045780 13 0.088
phagocytosis GO:0006909 66 0.088
cellular response to glucose stimulus GO:0071333 45 0.088
hair cycle GO:0042633 90 0.087
peptidyl serine modification GO:0018209 83 0.087
modification dependent protein catabolic process GO:0019941 133 0.086
nucleobase containing small molecule metabolic process GO:0055086 352 0.085
morphogenesis of a branching epithelium GO:0061138 193 0.084
response to organonitrogen compound GO:0010243 246 0.083
cellular response to hexose stimulus GO:0071331 47 0.082
receptor mediated endocytosis GO:0006898 51 0.082
negative regulation of molecular function GO:0044092 258 0.082
Rat
purine nucleoside triphosphate catabolic process GO:0009146 203 0.082
palate development GO:0060021 76 0.082
cerebral cortex development GO:0021987 86 0.081
negative regulation of lipid transport GO:0032369 8 0.080
ventricular septum development GO:0003281 42 0.079
positive regulation of binding GO:0051099 49 0.079
protein modification by small protein conjugation GO:0032446 187 0.078
rna polyadenylation GO:0043631 6 0.078
negative regulation of ras protein signal transduction GO:0046580 18 0.078
muscle cell migration GO:0014812 19 0.076
regulation of epidermal growth factor activated receptor activity GO:0007176 7 0.076
glutamate receptor signaling pathway GO:0007215 35 0.075
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.075
regulation of organ morphogenesis GO:2000027 144 0.074
mammary gland morphogenesis GO:0060443 54 0.073
regulation of bone resorption GO:0045124 24 0.073
regulation of peptide secretion GO:0002791 77 0.073
tissue remodeling GO:0048771 102 0.073
purine nucleoside metabolic process GO:0042278 241 0.072
gland development GO:0048732 330 0.071
body morphogenesis GO:0010171 45 0.071
hormone secretion GO:0046879 128 0.071
ion transmembrane transport GO:0034220 361 0.070
Mouse
protein autophosphorylation GO:0046777 61 0.070
skeletal system development GO:0001501 356 0.069
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.069
branching morphogenesis of an epithelial tube GO:0048754 159 0.069
stem cell maintenance GO:0019827 130 0.069
lung development GO:0030324 164 0.069
morphogenesis of a branching structure GO:0001763 203 0.068
oocyte axis specification GO:0007309 2 0.068
chemotaxis GO:0006935 247 0.068
synaptic transmission gabaergic GO:0051932 19 0.067
pole plasm assembly GO:0007315 2 0.067
regulation of cell proliferation involved in outflow tract morphogenesis GO:1901963 2 0.066
cell proliferation involved in heart morphogenesis GO:0061323 15 0.066
mammary gland duct morphogenesis GO:0060603 38 0.065
somatic stem cell division GO:0048103 19 0.065
protein import GO:0017038 101 0.064
neural tube closure GO:0001843 90 0.063
endoderm development GO:0007492 45 0.063
cognition GO:0050890 149 0.063
Mouse
myeloid leukocyte migration GO:0097529 57 0.061
somite development GO:0061053 81 0.061
aorta development GO:0035904 23 0.060
cerebellum development GO:0021549 77 0.060
positive regulation of actin filament polymerization GO:0030838 26 0.060
radial glial cell differentiation GO:0060019 6 0.060
cell growth GO:0016049 130 0.060
endodermal cell fate commitment GO:0001711 12 0.059
cardiac atrium morphogenesis GO:0003209 23 0.059
canonical wnt signaling pathway GO:0060070 130 0.058
osteoblast proliferation GO:0033687 18 0.058
epithelial tube morphogenesis GO:0060562 303 0.057
regulation of embryonic development GO:0045995 71 0.057
trachea cartilage development GO:0060534 8 0.057
nucleoside metabolic process GO:0009116 246 0.057
ossification GO:0001503 216 0.057
meiotic cell cycle GO:0051321 122 0.056
ectodermal placode morphogenesis GO:0071697 16 0.055
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.055
cardiac muscle tissue morphogenesis GO:0055008 44 0.055
meiotic nuclear division GO:0007126 115 0.054
artery development GO:0060840 53 0.053
retina morphogenesis in camera type eye GO:0060042 45 0.053
organic anion transport GO:0015711 137 0.053
nucleotide metabolic process GO:0009117 332 0.053
stem cell division GO:0017145 30 0.053
cell cell signaling involved in mammary gland development GO:0060764 2 0.053
regulation of mesenchymal cell proliferation GO:0010464 37 0.053
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.053
maternal determination of anterior posterior axis embryo GO:0008358 2 0.053
organonitrogen compound biosynthetic process GO:1901566 192 0.052
cardiac septum morphogenesis GO:0060411 46 0.051
regulation of peptide transport GO:0090087 91 0.050
single fertilization GO:0007338 82 0.050
regulation of membrane potential GO:0042391 192 0.049
Mouse
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.049
axon guidance GO:0007411 141 0.049
embryonic camera type eye development GO:0031076 36 0.048
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.048
defecation GO:0030421 1 0.048
stress activated protein kinase signaling cascade GO:0031098 81 0.048
negative regulation of wnt signaling pathway GO:0030178 73 0.048
negative regulation of cell proliferation GO:0008285 296 0.048
positive regulation of tissue remodeling GO:0034105 19 0.048
positive regulation of growth GO:0045927 104 0.048
embryonic heart tube morphogenesis GO:0003143 51 0.048
ectodermal placode formation GO:0060788 16 0.047
regulation of clathrin mediated endocytosis GO:2000369 4 0.047
ribonucleoside triphosphate metabolic process GO:0009199 220 0.046
rna processing GO:0006396 105 0.046
positive regulation of neural precursor cell proliferation GO:2000179 42 0.046
cardiocyte differentiation GO:0035051 87 0.045
glycoprotein metabolic process GO:0009100 116 0.045
synaptic vesicle recycling GO:0036465 19 0.045
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.045
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.045
multicellular organismal homeostasis GO:0048871 164 0.045
regulation of bone remodeling GO:0046850 28 0.045
oocyte construction GO:0007308 2 0.045
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.045
epidermis development GO:0008544 187 0.044
mesenchymal cell proliferation GO:0010463 44 0.044
regulation of wnt signaling pathway GO:0030111 123 0.044
regulation of secretion by cell GO:1903530 249 0.044
negative regulation of striated muscle tissue development GO:0045843 18 0.044
endoplasmic reticulum calcium ion homeostasis GO:0032469 11 0.044
regulation of ossification GO:0030278 112 0.044
exocytosis GO:0006887 121 0.044
insulin secretion GO:0030073 89 0.043
oocyte anterior posterior axis specification GO:0007314 2 0.043
synaptic transmission GO:0007268 329 0.043
Mouse Fly
purine nucleoside triphosphate metabolic process GO:0009144 226 0.042
transition metal ion homeostasis GO:0055076 54 0.042
memory GO:0007613 58 0.042
actin polymerization or depolymerization GO:0008154 54 0.042
guanosine containing compound catabolic process GO:1901069 144 0.042
odontogenesis GO:0042476 78 0.042
regulation of dna binding GO:0051101 39 0.041
neuron neuron synaptic transmission GO:0007270 69 0.041
Mouse

Mapk8ip1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.053
disease of anatomical entity DOID:7 0 0.053
nervous system disease DOID:863 0 0.053