Mus musculus

0 known processes

Mastl

microtubule associated serine/threonine kinase-like

(Aliases: MGC117975,C88295,2700091H24Rik,THC2)

Mastl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of microtubule based process GO:0032886 52 0.421
regulation of cell cycle GO:0051726 281 0.353
Human
negative regulation of cellular component organization GO:0051129 194 0.340
male meiosis GO:0007140 37 0.261
microtubule cytoskeleton organization GO:0000226 157 0.260
ubiquitin dependent protein catabolic process GO:0006511 129 0.254
meiotic cell cycle GO:0051321 122 0.247
nuclear division GO:0000280 158 0.244
Human
microtubule based process GO:0007017 236 0.237
cellular macromolecule catabolic process GO:0044265 206 0.225
organelle fission GO:0048285 170 0.222
Human
meiotic cell cycle process GO:1903046 77 0.214
cellular response to dna damage stimulus GO:0006974 207 0.206
regulation of microtubule cytoskeleton organization GO:0070507 37 0.196
meiotic nuclear division GO:0007126 115 0.186
macromolecule catabolic process GO:0009057 281 0.184
negative regulation of organelle organization GO:0010639 90 0.183
microtubule polymerization or depolymerization GO:0031109 26 0.178
mitotic cell cycle process GO:1903047 159 0.165
Human
negative regulation of cell cycle phase transition GO:1901988 48 0.153
mitotic cell cycle GO:0000278 195 0.134
Human
centrosome separation GO:0051299 4 0.126
regulation of cytoskeleton organization GO:0051493 122 0.122
microtubule organizing center organization GO:0031023 28 0.121
negative regulation of nuclear division GO:0051784 19 0.121
regulation of cell cycle process GO:0010564 160 0.118
regulation of organelle organization GO:0033043 289 0.104
protein catabolic process GO:0030163 221 0.098
chromosome separation GO:0051304 14 0.098
cellular amino acid metabolic process GO:0006520 103 0.096
regulation of cellular amino acid metabolic process GO:0006521 5 0.090
male gamete generation GO:0048232 285 0.089
negative regulation of protein depolymerization GO:1901880 21 0.087
cellular amine metabolic process GO:0044106 44 0.087
negative regulation of cell cycle process GO:0010948 69 0.082
regulation of mitotic cell cycle GO:0007346 126 0.082
regulation of cellular amine metabolic process GO:0033238 20 0.078
dna repair GO:0006281 107 0.075
modification dependent macromolecule catabolic process GO:0043632 133 0.070
cellular ketone metabolic process GO:0042180 84 0.067
amine metabolic process GO:0009308 45 0.066
regulation of cellular ketone metabolic process GO:0010565 66 0.066
centrosome cycle GO:0007098 23 0.066
maintenance of location GO:0051235 89 0.066
microtubule nucleation GO:0007020 2 0.064
negative regulation of cell cycle GO:0045786 123 0.059
organelle assembly GO:0070925 177 0.054
negative regulation of mitotic cell cycle GO:0045930 58 0.053
modification dependent protein catabolic process GO:0019941 133 0.053
organic cyclic compound catabolic process GO:1901361 295 0.053
centrosome organization GO:0051297 26 0.052
regulation of protein localization GO:0032880 231 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
protein modification by small protein conjugation or removal GO:0070647 207 0.047
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.045
protein modification by small protein conjugation GO:0032446 187 0.043
dna metabolic process GO:0006259 303 0.043
regulation of mitotic cell cycle phase transition GO:1901990 73 0.043
microtubule polymerization GO:0046785 12 0.042
organophosphate catabolic process GO:0046434 232 0.042
response to radiation GO:0009314 165 0.041
negative regulation of cytoskeleton organization GO:0051494 36 0.041
double strand break repair GO:0006302 48 0.040
female meiosis chromosome segregation GO:0016321 1 0.040
aromatic compound catabolic process GO:0019439 286 0.039
regulation of cellular response to stress GO:0080135 159 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.039
germ cell development GO:0007281 185 0.039
negative regulation of cellular catabolic process GO:0031330 47 0.038
regulation of transferase activity GO:0051338 263 0.038
establishment of meiotic spindle orientation GO:0051296 1 0.038
spermatogenesis GO:0007283 284 0.038
positive regulation of protein modification process GO:0031401 299 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.038
lateral inhibition GO:0046331 1 0.037
carbohydrate derivative catabolic process GO:1901136 231 0.036
nucleoside metabolic process GO:0009116 246 0.036
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.036
spindle assembly involved in female meiosis GO:0007056 3 0.035
negative regulation of protein metabolic process GO:0051248 282 0.035
ribonucleoside metabolic process GO:0009119 245 0.035
glycosyl compound catabolic process GO:1901658 206 0.035
regulation of cell division GO:0051302 76 0.034
nucleotide metabolic process GO:0009117 332 0.034
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.034
purine ribonucleotide metabolic process GO:0009150 290 0.034
regulation of chromosome organization GO:0033044 83 0.033
meiotic chromosome movement towards spindle pole GO:0016344 3 0.033
heterocycle catabolic process GO:0046700 280 0.033
blood vessel morphogenesis GO:0048514 285 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
spindle assembly involved in meiosis GO:0090306 4 0.033
organonitrogen compound catabolic process GO:1901565 264 0.033
astral microtubule organization GO:0030953 3 0.032
response to light stimulus GO:0009416 135 0.032
ribonucleoside catabolic process GO:0042454 206 0.032
negative regulation of cell division GO:0051782 24 0.032
female meiotic division GO:0007143 21 0.031
protein methylation GO:0006479 81 0.031
cell division GO:0051301 120 0.030
cellularization GO:0007349 1 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
regulation of protein maturation GO:1903317 96 0.030
purine nucleotide catabolic process GO:0006195 211 0.029
chromosome segregation GO:0007059 48 0.029
macromolecule methylation GO:0043414 120 0.029
cellular protein complex disassembly GO:0043624 36 0.029
stem cell differentiation GO:0048863 268 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
synapsis GO:0007129 34 0.028
regulation of spindle organization GO:0090224 2 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
nucleotide catabolic process GO:0009166 217 0.028
attachment of spindle microtubules to kinetochore GO:0008608 4 0.028
regulation of neural precursor cell proliferation GO:2000177 70 0.028
meiosis i GO:0007127 60 0.027
dna recombination GO:0006310 92 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.027
spindle assembly involved in mitosis GO:0090307 4 0.027
establishment of organelle localization GO:0051656 122 0.027
regulation of microtubule depolymerization GO:0031114 13 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
cellular protein catabolic process GO:0044257 155 0.026
t cell activation GO:0042110 289 0.026
kinetochore organization GO:0051383 2 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.026
mitotic nuclear division GO:0007067 48 0.026
Human
nucleoside triphosphate catabolic process GO:0009143 205 0.026
negative regulation of cellular protein catabolic process GO:1903363 22 0.025
cellular protein complex assembly GO:0043623 116 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
spermatid development GO:0007286 108 0.025
oxidation reduction process GO:0055114 342 0.025
positive regulation of mitotic cell cycle GO:0045931 41 0.025
purine nucleotide metabolic process GO:0006163 302 0.024
histone h3 k9 dimethylation GO:0036123 4 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
tube formation GO:0035148 140 0.024
neural tube formation GO:0001841 108 0.024
purine nucleoside catabolic process GO:0006152 205 0.024
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.024
regulation of protein complex disassembly GO:0043244 28 0.024
mitotic cell cycle checkpoint GO:0007093 31 0.024
peptidyl amino acid modification GO:0018193 336 0.024
purine nucleoside metabolic process GO:0042278 241 0.023
neuron migration GO:0001764 122 0.023
protein maturation GO:0051604 176 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
regulation of cell cycle phase transition GO:1901987 77 0.023
endomembrane system organization GO:0010256 147 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
nucleoside catabolic process GO:0009164 206 0.022
regulation of nuclear division GO:0051783 56 0.022
spindle assembly GO:0051225 13 0.022
stem cell development GO:0048864 219 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
regulation of mitosis GO:0007088 29 0.022
dna catabolic process endonucleolytic GO:0000737 15 0.021
embryonic epithelial tube formation GO:0001838 130 0.021
positive regulation of protein kinase activity GO:0045860 144 0.021
histone threonine phosphorylation GO:0035405 1 0.021
apoptotic signaling pathway GO:0097190 306 0.021
response to organonitrogen compound GO:0010243 246 0.020
methylation GO:0032259 134 0.020
nucleoside monophosphate metabolic process GO:0009123 85 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.020
regulation of cellular protein catabolic process GO:1903362 61 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
anatomical structure homeostasis GO:0060249 145 0.020
mitotic cytokinesis GO:0000281 4 0.020
regulation of cell cycle g2 m phase transition GO:1902749 10 0.020
cytoplasmic transport GO:0016482 234 0.019
protein ubiquitination GO:0016567 171 0.019
establishment or maintenance of cell polarity GO:0007163 86 0.019
regulation of protein catabolic process GO:0042176 108 0.019
regulation of histone modification GO:0031056 56 0.019
positive regulation of kinase activity GO:0033674 155 0.019
regulation of cell activation GO:0050865 289 0.019
muscle tissue development GO:0060537 308 0.019
epithelial tube formation GO:0072175 130 0.019
protein polymerization GO:0051258 57 0.019
purine containing compound catabolic process GO:0072523 213 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
negative regulation of microtubule depolymerization GO:0007026 13 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
placenta development GO:0001890 140 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.018
dna damage checkpoint GO:0000077 26 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.018
sister chromatid segregation GO:0000819 20 0.018
regulation of protein processing GO:0070613 96 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
wnt signaling pathway GO:0016055 188 0.018
mitotic sister chromatid cohesion GO:0007064 1 0.018
regulation of response to dna damage stimulus GO:2001020 34 0.018
regulation of establishment of protein localization GO:0070201 181 0.017
protein depolymerization GO:0051261 34 0.017
leukocyte mediated immunity GO:0002443 174 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
purine containing compound metabolic process GO:0072521 311 0.017
microtubule depolymerization GO:0007019 15 0.017
nucleoside monophosphate catabolic process GO:0009125 59 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
rho protein signal transduction GO:0007266 32 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
regulation of cytokine production GO:0001817 266 0.017
membrane organization GO:0061024 245 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
cellular lipid metabolic process GO:0044255 323 0.017
organelle localization GO:0051640 179 0.017
immune effector process GO:0002252 321 0.016
establishment of spindle localization GO:0051293 19 0.016
cation transport GO:0006812 399 0.016
negative regulation of nervous system development GO:0051961 156 0.016
protein complex disassembly GO:0043241 40 0.016
positive regulation of cellular component biogenesis GO:0044089 94 0.016
developmental maturation GO:0021700 193 0.016
response to uv GO:0009411 44 0.016
leukocyte differentiation GO:0002521 342 0.016
atp catabolic process GO:0006200 55 0.016
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.016
protein polyubiquitination GO:0000209 33 0.016
chromosome organization involved in meiosis GO:0070192 39 0.016
cytokine production GO:0001816 319 0.016
spermatid differentiation GO:0048515 115 0.016
regulation of protein depolymerization GO:1901879 26 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.015
regulation of kinase activity GO:0043549 249 0.015
purine nucleoside monophosphate catabolic process GO:0009128 58 0.015
mitotic spindle organization GO:0007052 10 0.015
stem cell maintenance GO:0019827 130 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
mapk cascade GO:0000165 281 0.015
centrosome duplication GO:0051298 16 0.015
multicellular organismal signaling GO:0035637 91 0.015
centriole assembly GO:0098534 6 0.015
negative regulation of cell development GO:0010721 169 0.014
cellular response to gamma radiation GO:0071480 4 0.014
recombinational repair GO:0000725 21 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
negative regulation of proteolysis GO:0045861 74 0.014
response to organic cyclic compound GO:0014070 198 0.014
cytokinetic process GO:0032506 2 0.014
positive regulation of protein catabolic process GO:0045732 60 0.014
regulation of chromosome segregation GO:0051983 21 0.014
peptidyl lysine trimethylation GO:0018023 12 0.014
regulation of stem cell proliferation GO:0072091 78 0.014
pallium development GO:0021543 120 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
cell maturation GO:0048469 127 0.014
regulation of proteasomal protein catabolic process GO:0061136 46 0.014
translesion synthesis GO:0019985 1 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
lymphocyte differentiation GO:0030098 242 0.014
cell cycle checkpoint GO:0000075 47 0.014
regulation of intracellular transport GO:0032386 159 0.013
multicellular organism growth GO:0035264 161 0.013
negative regulation of transferase activity GO:0051348 85 0.013
lipid biosynthetic process GO:0008610 179 0.013
ras protein signal transduction GO:0007265 77 0.013
regulation of t cell activation GO:0050863 170 0.013
regulation of membrane potential GO:0042391 192 0.013
protein alkylation GO:0008213 81 0.013
neural precursor cell proliferation GO:0061351 121 0.013
negative regulation of protein processing GO:0010955 79 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
striated muscle tissue development GO:0014706 293 0.013
intracellular protein transport GO:0006886 204 0.013
dna catabolic process exonucleolytic GO:0000738 3 0.013
metaphase plate congression GO:0051310 2 0.013
negative regulation of protein complex disassembly GO:0043242 22 0.013
oogenesis GO:0048477 56 0.013
cell activation involved in immune response GO:0002263 126 0.013
regulation of response to wounding GO:1903034 189 0.013
microtubule based transport GO:0010970 50 0.013
divalent metal ion transport GO:0070838 172 0.013
neural tube development GO:0021915 160 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
histone h3 k9 methylation GO:0051567 17 0.013
heterochromatin organization GO:0070828 4 0.013
cytoskeleton dependent intracellular transport GO:0030705 50 0.013
atp metabolic process GO:0046034 75 0.013
positive regulation of cell cycle GO:0045787 92 0.013
action potential GO:0001508 78 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
regulation of mapk cascade GO:0043408 248 0.013
negative regulation of protein catabolic process GO:0042177 36 0.013
negative regulation of meiotic cell cycle phase transition GO:1901994 3 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
peptidyl lysine modification GO:0018205 77 0.012
male sex differentiation GO:0046661 109 0.012
angiogenesis GO:0001525 201 0.012
myeloid leukocyte activation GO:0002274 83 0.012
regulation of myeloid dendritic cell activation GO:0030885 5 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
cerebral cortex development GO:0021987 86 0.012
positive regulation of transferase activity GO:0051347 167 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
cell type specific apoptotic process GO:0097285 268 0.012
telencephalon development GO:0021537 186 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
regulation of neuron differentiation GO:0045664 281 0.012
positive regulation of cell development GO:0010720 237 0.012
protection from non homologous end joining at telomere GO:0031848 4 0.012
regulation of proteolysis GO:0030162 164 0.012
positive regulation of chromosome segregation GO:0051984 4 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
embryonic placenta development GO:0001892 98 0.012
meiotic dna repair synthesis GO:0000711 4 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
protein secretion GO:0009306 111 0.012
positive regulation of organelle organization GO:0010638 128 0.011
spindle organization GO:0007051 28 0.011
regulation of meiotic cell cycle GO:0051445 34 0.011
intracellular mrna localization GO:0008298 4 0.011
histone methylation GO:0016571 71 0.011
endocytosis GO:0006897 168 0.011
regulation of asymmetric cell division GO:0009786 4 0.011
regulation of sister chromatid segregation GO:0033045 13 0.011
mitotic recombination GO:0006312 3 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
reciprocal dna recombination GO:0035825 16 0.011
inflammatory response GO:0006954 244 0.011
fatty acid metabolic process GO:0006631 121 0.011
regulation of cell migration GO:0030334 219 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
chromatin modification GO:0016568 187 0.011
positive regulation of wnt signaling pathway GO:0030177 45 0.011
synaptonemal complex organization GO:0070193 15 0.011
protein localization to organelle GO:0033365 185 0.011
regulation of system process GO:0044057 200 0.011
positive regulation of nervous system development GO:0051962 221 0.011
mitotic spindle checkpoint GO:0071174 9 0.011
gland development GO:0048732 330 0.011
positive regulation of cell activation GO:0050867 158 0.011
b cell activation GO:0042113 161 0.011
cellular response to light stimulus GO:0071482 19 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
forebrain development GO:0030900 302 0.011
skeletal system development GO:0001501 356 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
cell adhesion GO:0007155 329 0.010
development of primary male sexual characteristics GO:0046546 88 0.010
regulation of dna recombination GO:0000018 34 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
positive regulation of cell death GO:0010942 224 0.010
asymmetric stem cell division GO:0098722 3 0.010
regulation of cell motility GO:2000145 236 0.010
transmission of nerve impulse GO:0019226 76 0.010
adaptive immune response GO:0002250 155 0.010
actin cytoskeleton organization GO:0030036 220 0.010
cleavage furrow formation GO:0036089 2 0.010
negative regulation of protein maturation GO:1903318 79 0.010

Mastl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.067
Human
disease of anatomical entity DOID:7 0 0.067
Human
disease of cellular proliferation DOID:14566 0 0.065
cancer DOID:162 0 0.048
thoracic cancer DOID:5093 0 0.034
organ system cancer DOID:0050686 0 0.034
hematopoietic system disease DOID:74 0 0.031
Human
breast cancer DOID:1612 0 0.028
aplastic anemia DOID:12449 0 0.024
bone marrow disease DOID:4961 0 0.024
anemia DOID:2355 0 0.024
congenital hypoplastic anemia DOID:1342 0 0.019
physical disorder DOID:0080015 0 0.018
congenital nervous system abnormality DOID:2490 0 0.018