Mus musculus

14 known processes

Mbtd1

mbt domain containing 1

(Aliases: hemp,AA408199,AI194990)

Mbtd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.830
histone modification GO:0016570 159 0.517
mirna catabolic process GO:0010587 2 0.481
chromatin modification GO:0016568 187 0.452
covalent chromatin modification GO:0016569 163 0.449
chromatin organization GO:0006325 206 0.376
cellular response to dna damage stimulus GO:0006974 207 0.281
spermatogenesis GO:0007283 284 0.269
gene silencing GO:0016458 38 0.234
Fly
histone methylation GO:0016571 71 0.190
gene silencing by rna GO:0031047 19 0.158
intracellular receptor signaling pathway GO:0030522 74 0.134
posttranscriptional regulation of gene expression GO:0010608 155 0.130
inner cell mass cell fate commitment GO:0001827 2 0.129
posttranscriptional gene silencing GO:0016441 10 0.125
peptidyl amino acid modification GO:0018193 336 0.117
genitalia development GO:0048806 37 0.109
gene silencing by mirna GO:0035195 10 0.108
multicellular organism growth GO:0035264 161 0.107
spermatid differentiation GO:0048515 115 0.103
macromolecule catabolic process GO:0009057 281 0.096
male gamete generation GO:0048232 285 0.094
germ cell development GO:0007281 185 0.089
Fly
amine metabolic process GO:0009308 45 0.087
development of primary sexual characteristics GO:0045137 143 0.084
peptidyl lysine methylation GO:0018022 29 0.084
dna recombination GO:0006310 92 0.083
regulation of chromatin modification GO:1903308 57 0.083
regulation of histone h3 k9 methylation GO:0051570 8 0.082
rna catabolic process GO:0006401 29 0.079
regulation of chromatin silencing GO:0031935 2 0.073
protein modification by small protein conjugation or removal GO:0070647 207 0.073
posttranscriptional gene silencing by rna GO:0035194 10 0.071
chromatin silencing GO:0006342 15 0.069
Fly
dna repair GO:0006281 107 0.069
positive regulation of organelle organization GO:0010638 128 0.069
regulation of organelle organization GO:0033043 289 0.067
mrna metabolic process GO:0016071 84 0.063
nuclear division GO:0000280 158 0.062
cellular response to lipid GO:0071396 145 0.062
rna splicing via transesterification reactions GO:0000375 43 0.060
habenula development GO:0021986 2 0.060
positive regulation of protein modification process GO:0031401 299 0.059
internal protein amino acid acetylation GO:0006475 42 0.059
histone h3 k9 methylation GO:0051567 17 0.057
dna methylation GO:0006306 43 0.055
aromatic compound catabolic process GO:0019439 286 0.053
negative regulation of cellular protein metabolic process GO:0032269 247 0.052
rna processing GO:0006396 105 0.052
metanephric thick ascending limb development GO:0072233 2 0.052
regulation of histone deacetylation GO:0031063 12 0.051
histone lysine methylation GO:0034968 50 0.049
cellular macromolecule catabolic process GO:0044265 206 0.049
peptidyl lysine modification GO:0018205 77 0.049
histone h3 k4 trimethylation GO:0080182 5 0.049
demethylation GO:0070988 23 0.048
regulation of t cell proliferation GO:0042129 92 0.048
cellular ketone metabolic process GO:0042180 84 0.047
peptidyl serine phosphorylation GO:0018105 74 0.047
organic cyclic compound catabolic process GO:1901361 295 0.046
epithalamus development GO:0021538 2 0.046
heterocycle catabolic process GO:0046700 280 0.045
positive regulation of cellular amine metabolic process GO:0033240 5 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
cellular amino acid metabolic process GO:0006520 103 0.042
regulation of histone modification GO:0031056 56 0.041
protein modification by small protein conjugation GO:0032446 187 0.041
immunoglobulin secretion involved in immune response GO:0002380 2 0.041
protein catabolic process GO:0030163 221 0.041
negative regulation of relaxation of muscle GO:1901078 2 0.040
negative regulation of histone methylation GO:0031061 10 0.040
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.038
regulation of peptidyl serine phosphorylation GO:0033135 39 0.036
leukocyte differentiation GO:0002521 342 0.035
Mouse
negative regulation of cellular component organization GO:0051129 194 0.035
sensory organ morphogenesis GO:0090596 242 0.034
negative regulation of gene expression epigenetic GO:0045814 15 0.034
Fly
translation GO:0006412 93 0.033
negative regulation of protein metabolic process GO:0051248 282 0.032
response to organic cyclic compound GO:0014070 198 0.032
proprioception GO:0019230 4 0.031
macromolecule methylation GO:0043414 120 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
embryonic organ morphogenesis GO:0048562 276 0.030
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.029
cytokine production GO:0001816 319 0.029
cellular response to organic cyclic compound GO:0071407 87 0.028
regulation of chromosome organization GO:0033044 83 0.028
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.027
positive regulation of histone h3 k9 methylation GO:0051574 4 0.026
regulation of protein stability GO:0031647 52 0.026
somatotropin secreting cell differentiation GO:0060126 4 0.026
positive regulation of cytokine production GO:0001819 174 0.026
protein methylation GO:0006479 81 0.026
methylation GO:0032259 134 0.025
negative regulation of histone modification GO:0031057 18 0.025
stem cell fate specification GO:0048866 3 0.024
epithelial cell development GO:0002064 159 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.024
small molecule biosynthetic process GO:0044283 132 0.024
t cell activation GO:0042110 289 0.024
mrna processing GO:0006397 63 0.024
camera type eye development GO:0043010 266 0.024
regulation of lymphocyte activation GO:0051249 240 0.024
positive regulation of histone h3 k27 methylation GO:0061087 4 0.023
ubiquitin dependent protein catabolic process GO:0006511 129 0.023
positive regulation of gene silencing by mirna GO:2000637 1 0.023
mitotic sister chromatid cohesion GO:0007064 1 0.023
dna modification GO:0006304 50 0.023
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.023
cell cycle checkpoint GO:0000075 47 0.023
regulation of mrna processing GO:0050684 41 0.023
cellular response to molecule of bacterial origin GO:0071219 83 0.022
rna interference GO:0016246 2 0.022
cellular amine metabolic process GO:0044106 44 0.022
endocytosis GO:0006897 168 0.022
double strand break repair GO:0006302 48 0.022
histone deubiquitination GO:0016578 2 0.022
protein alkylation GO:0008213 81 0.022
cation transmembrane transport GO:0098655 266 0.022
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.021
negative regulation of immune system process GO:0002683 209 0.021
negative regulation of organelle organization GO:0010639 90 0.021
internal peptidyl lysine acetylation GO:0018393 42 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
nuclear transcribed mrna catabolic process GO:0000956 16 0.021
spermatid development GO:0007286 108 0.021
regulation of cell migration GO:0030334 219 0.020
regulation of cell activation GO:0050865 289 0.020
regulation of cellular amine metabolic process GO:0033238 20 0.020
central nervous system neuron differentiation GO:0021953 162 0.020
regulation of chromatin organization GO:1902275 57 0.020
insulin like growth factor receptor signaling pathway GO:0048009 21 0.019
homeostasis of number of cells GO:0048872 210 0.019
Mouse
dct cell differentiation GO:0072069 3 0.019
mrna transcription GO:0009299 4 0.019
protein deacylation GO:0035601 36 0.019
negative regulation of synapse assembly GO:0051964 3 0.019
positive regulation of histone modification GO:0031058 28 0.019
glycerolipid metabolic process GO:0046486 122 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
regulation of mapk cascade GO:0043408 248 0.018
positive regulation of chromatin modification GO:1903310 28 0.018
neuron projection guidance GO:0097485 141 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
response to nutrient levels GO:0031667 109 0.018
terminal button organization GO:0072553 3 0.018
bmp signaling pathway GO:0030509 93 0.018
negative regulation of bmp signaling pathway GO:0030514 35 0.017
cellular response to monoamine stimulus GO:0071868 3 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
ear morphogenesis GO:0042471 118 0.017
stem cell differentiation GO:0048863 268 0.017
response to acid chemical GO:0001101 111 0.017
leukocyte proliferation GO:0070661 172 0.017
digestive tract morphogenesis GO:0048546 147 0.017
response to radiation GO:0009314 165 0.017
metanephric loop of henle development GO:0072236 4 0.017
uterus morphogenesis GO:0061038 2 0.016
monoubiquitinated histone deubiquitination GO:0035521 1 0.016
dna dealkylation GO:0035510 11 0.016
jak stat cascade GO:0007259 42 0.016
negative regulation of protein modification process GO:0031400 163 0.016
sensory perception GO:0007600 245 0.016
peptidyl lysine acetylation GO:0018394 45 0.016
negative regulation of dna replication GO:0008156 4 0.016
inorganic cation transmembrane transport GO:0098662 207 0.015
inner ear receptor cell differentiation GO:0060113 61 0.015
sister chromatid segregation GO:0000819 20 0.015
leukocyte migration GO:0050900 124 0.015
regulation of translation GO:0006417 71 0.015
meiotic nuclear division GO:0007126 115 0.015
regulation of peptidyl threonine phosphorylation GO:0010799 12 0.015
regulation of multi organism process GO:0043900 111 0.015
negative regulation of mitotic cell cycle GO:0045930 58 0.015
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.015
histone lysine demethylation GO:0070076 13 0.015
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.015
respiratory system development GO:0060541 190 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
cellular homeostasis GO:0019725 240 0.015
cell chemotaxis GO:0060326 81 0.015
regulation of mrna splicing via spliceosome GO:0048024 32 0.014
embryonic limb morphogenesis GO:0030326 126 0.014
macromolecule deacylation GO:0098732 37 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
meiosis i GO:0007127 60 0.014
cell division GO:0051301 120 0.014
notch signaling pathway GO:0007219 71 0.014
negative regulation of chromatin silencing GO:0031936 1 0.014
meiotic cell cycle GO:0051321 122 0.014
t cell differentiation GO:0030217 174 0.014
histone h3 k9 dimethylation GO:0036123 4 0.014
regulation of neuron differentiation GO:0045664 281 0.013
peptidyl serine modification GO:0018209 83 0.013
chromatin silencing at rdna GO:0000183 3 0.013
negative regulation of lymphocyte activation GO:0051250 91 0.013
cellular response to catecholamine stimulus GO:0071870 3 0.013
regulation of t cell activation GO:0050863 170 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
regulation of cell division GO:0051302 76 0.013
regulation of inositol phosphate biosynthetic process GO:0010919 3 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
appendage development GO:0048736 166 0.013
spermatid nucleus elongation GO:0007290 4 0.013
inner ear morphogenesis GO:0042472 101 0.013
gonad development GO:0008406 141 0.013
metanephric dct cell differentiation GO:0072240 3 0.013
dna packaging GO:0006323 30 0.013
mesenchymal cell apoptotic process GO:0097152 14 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
epithelial cell proliferation GO:0050673 174 0.013
b cell activation GO:0042113 161 0.013
histone acetylation GO:0016573 41 0.013
histone deacetylation GO:0016575 26 0.013
heart morphogenesis GO:0003007 178 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
gland development GO:0048732 330 0.013
axon guidance GO:0007411 141 0.013
female sex differentiation GO:0046660 84 0.013
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.012
dna integrity checkpoint GO:0031570 28 0.012
lung development GO:0030324 164 0.012
regulation of cytokine production GO:0001817 266 0.012
peptidyl lysine trimethylation GO:0018023 12 0.012
lymphocyte proliferation GO:0046651 164 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.012
ear development GO:0043583 200 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
regulation of rna splicing GO:0043484 37 0.012
neurohypophysis development GO:0021985 2 0.012
dna damage checkpoint GO:0000077 26 0.012
cellular lipid metabolic process GO:0044255 323 0.012
morphogenesis of an endothelium GO:0003159 2 0.012
regulation of inositol trisphosphate biosynthetic process GO:0032960 3 0.012
innate immune response GO:0045087 157 0.012
protein acylation GO:0043543 64 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.012
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.012
mrna catabolic process GO:0006402 22 0.012
protein deacetylation GO:0006476 32 0.011
regulation of bmp signaling pathway GO:0030510 60 0.011
mesenchyme development GO:0060485 152 0.011
negative regulation of leukocyte proliferation GO:0070664 46 0.011
negative regulation of chromatin modification GO:1903309 19 0.011
immunoglobulin production GO:0002377 73 0.011
smad protein complex assembly GO:0007183 1 0.011
diencephalon development GO:0021536 63 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
pharynx development GO:0060465 1 0.011
cellular response to epinephrine stimulus GO:0071872 3 0.011
thick ascending limb development GO:0072023 2 0.011
nucleotide catabolic process GO:0009166 217 0.011
regulation of cell cycle GO:0051726 281 0.011
regulation of b cell activation GO:0050864 81 0.011
regulation of voltage gated calcium channel activity GO:1901385 4 0.011
positive regulation of chromosome organization GO:2001252 33 0.011
respiratory tube development GO:0030323 167 0.011
muscle contraction GO:0006936 101 0.011
apoptotic signaling pathway GO:0097190 306 0.011
regulation of mrna metabolic process GO:1903311 43 0.011
forebrain development GO:0030900 302 0.011
regulation of gene silencing GO:0060968 7 0.011
t cell proliferation GO:0042098 120 0.011
gall bladder development GO:0061010 2 0.011
embryonic digestive tract development GO:0048566 27 0.011
chemotaxis GO:0006935 247 0.011
equilibrioception GO:0050957 3 0.011
mitotic chromosome condensation GO:0007076 1 0.010
cellular ion homeostasis GO:0006873 165 0.010
response to lipopolysaccharide GO:0032496 128 0.010
chromatin remodeling GO:0006338 32 0.010
regulation of cytoplasmic mrna processing body assembly GO:0010603 2 0.010
response to catecholamine GO:0071869 4 0.010
lymphocyte differentiation GO:0030098 242 0.010
protein ubiquitination GO:0016567 171 0.010

Mbtd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010