|
|
positive regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902110 |
11 |
0.996
|
Mouse |
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.964
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.926
|
Mouse |
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
17 |
0.926
|
Worm |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.923
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
27 |
0.915
|
Worm |
|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
5 |
0.914
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.890
|
Mouse |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.890
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.876
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.854
|
Mouse |
|
|
positive regulation of mitochondrial membrane permeability
|
GO:0035794 |
12 |
0.844
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.843
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.839
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.827
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.817
|
|
|
|
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901030 |
6 |
0.806
|
|
|
|
mitochondrial membrane organization
|
GO:0007006 |
26 |
0.803
|
Mouse |
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.801
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.800
|
Mouse |
|
|
negative regulation of fibroblast proliferation
|
GO:0048147 |
14 |
0.799
|
Mouse |
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.794
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.777
|
Zebrafish Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.764
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.761
|
Mouse |
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.758
|
Mouse |
|
|
mitochondrial transport
|
GO:0006839 |
36 |
0.758
|
Mouse |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.756
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.744
|
Mouse |
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.734
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.702
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.695
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.687
|
Mouse |
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.681
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.681
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.671
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.670
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.656
|
Mouse |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.655
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.653
|
Zebrafish Mouse |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.645
|
Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.639
|
Zebrafish Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.632
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.630
|
|
|
|
regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902108 |
14 |
0.628
|
Mouse |
|
|
positive regulation of protein oligomerization
|
GO:0032461 |
4 |
0.623
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.611
|
Mouse |
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
17 |
0.611
|
Mouse |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.594
|
Mouse |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.583
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.583
|
Mouse |
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.581
|
Mouse |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.566
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.563
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.563
|
Mouse |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.555
|
Mouse |
|
|
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
|
GO:1900740 |
3 |
0.554
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.551
|
|
|
|
cellular response to glucose starvation
|
GO:0042149 |
5 |
0.547
|
Mouse |
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.539
|
Mouse |
|
|
mitochondrial outer membrane permeabilization
|
GO:0097345 |
10 |
0.534
|
Mouse |
|
|
protein processing
|
GO:0016485 |
163 |
0.530
|
Zebrafish Mouse |
|
|
protein maturation
|
GO:0051604 |
176 |
0.525
|
Zebrafish Mouse |
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.519
|
Mouse |
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.513
|
Mouse |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.512
|
Mouse |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.503
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.499
|
Mouse |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.495
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.495
|
|
|
|
establishment of protein localization to mitochondrion
|
GO:0072655 |
11 |
0.494
|
Mouse |
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.483
|
Mouse |
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.482
|
Mouse |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.475
|
Mouse |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.450
|
Zebrafish Mouse Worm |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.449
|
Human Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.447
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.443
|
Mouse |
|
|
response to dsrna
|
GO:0043331 |
30 |
0.442
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.436
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
28 |
0.435
|
|
|
|
protein insertion into mitochondrial membrane
|
GO:0051204 |
4 |
0.430
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.429
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
25 |
0.422
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.419
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.413
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.408
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.392
|
Mouse |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.391
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.390
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.384
|
Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.378
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.364
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.359
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.359
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.357
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.352
|
Mouse |
|
|
gland development
|
GO:0048732 |
330 |
0.347
|
Mouse |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.334
|
Worm |
|
|
defense response to virus
|
GO:0051607 |
68 |
0.331
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.324
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.322
|
Mouse Worm |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.321
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.317
|
Mouse |
|
|
cellular response to oxygen levels
|
GO:0071453 |
20 |
0.314
|
Mouse |
|
|
response to radiation
|
GO:0009314 |
165 |
0.314
|
Mouse |
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.313
|
Mouse |
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.307
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.303
|
Zebrafish Mouse |
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.301
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
11 |
0.300
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.296
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.294
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.288
|
|
|
|
gene silencing by mirna
|
GO:0035195 |
10 |
0.281
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.277
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.276
|
Mouse |
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
34 |
0.273
|
Mouse |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.272
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.269
|
Mouse |
|
|
response to peptide
|
GO:1901652 |
136 |
0.259
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.255
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.252
|
Mouse |
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.249
|
Mouse |
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.247
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.246
|
Mouse |
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.241
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.240
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.239
|
Worm |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.238
|
Zebrafish Worm |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.235
|
Worm |
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.232
|
Worm |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.229
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.228
|
Mouse Worm |
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.221
|
Mouse |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.220
|
Mouse |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.219
|
Worm |
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.215
|
Zebrafish Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.212
|
Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.212
|
Mouse |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.211
|
Mouse |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.207
|
|
|
|
response to x ray
|
GO:0010165 |
11 |
0.207
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.206
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
17 |
0.206
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.199
|
Mouse |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.199
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.198
|
Mouse |
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.197
|
Mouse |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.196
|
Worm |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.195
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.193
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.192
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.188
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.187
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.182
|
Mouse |
|
|
angiogenesis
|
GO:0001525 |
201 |
0.178
|
Mouse |
|
|
response to starvation
|
GO:0042594 |
65 |
0.177
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.175
|
Mouse |
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.175
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.174
|
Worm |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.174
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.172
|
Mouse |
|
|
skin development
|
GO:0043588 |
220 |
0.169
|
Mouse |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.167
|
Mouse |
|
|
stem cell development
|
GO:0048864 |
219 |
0.167
|
Mouse |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.164
|
Worm |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.163
|
Mouse |
|
|
negative regulation of membrane potential
|
GO:0045837 |
4 |
0.163
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.159
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.158
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.156
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.155
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.155
|
Mouse |
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.155
|
Mouse |
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.154
|
Mouse |
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.153
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.153
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.150
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.148
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.147
|
|
|
|
regulation of developmental pigmentation
|
GO:0048070 |
14 |
0.143
|
Mouse |
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.143
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.142
|
Mouse |
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.141
|
Mouse |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.139
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.139
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.139
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.136
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.135
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.135
|
Mouse |
|
|
protein acylation
|
GO:0043543 |
64 |
0.135
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.131
|
Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.127
|
Zebrafish Mouse |
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.125
|
Mouse |
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.124
|
Mouse |
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.124
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.124
|
Mouse |
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.123
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.122
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.121
|
Worm |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.121
|
Worm |
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.121
|
Mouse |
|
|
viral process
|
GO:0016032 |
41 |
0.119
|
Mouse |
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.119
|
Mouse |
|
|
digestive tract development
|
GO:0048565 |
190 |
0.118
|
Mouse |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.118
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.117
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.117
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.117
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.116
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.114
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.112
|
Zebrafish Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.111
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.109
|
Mouse |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.109
|
Mouse |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.107
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.107
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.107
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.107
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.105
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.105
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.105
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.104
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.102
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.102
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.101
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.101
|
Worm |
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.100
|
Mouse |
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.099
|
|
|
|
response to superoxide
|
GO:0000303 |
16 |
0.099
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.099
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.098
|
Mouse |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.097
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.095
|
|
|
|
negative regulation of peptidyl serine phosphorylation
|
GO:0033137 |
10 |
0.095
|
Mouse |
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.094
|
|
|
|
spongiotrophoblast layer development
|
GO:0060712 |
15 |
0.094
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.094
|
Worm |
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.094
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.094
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.094
|
Mouse |
|
|
cation transport
|
GO:0006812 |
399 |
0.094
|
Mouse |
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.091
|
Mouse |
|
|
fibroblast apoptotic process
|
GO:0044346 |
9 |
0.091
|
Mouse |
|
|
cellular response to oxygen radical
|
GO:0071450 |
14 |
0.091
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
14 |
0.091
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.090
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.088
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.087
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
32 |
0.087
|
Mouse |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.086
|
|
|
|
thymus development
|
GO:0048538 |
41 |
0.086
|
Mouse |
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.086
|
Mouse |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.086
|
Mouse |
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.085
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.084
|
|
|
|
regulation of b cell apoptotic process
|
GO:0002902 |
13 |
0.084
|
Mouse |
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.084
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.084
|
|
|
|
post embryonic camera type eye development
|
GO:0031077 |
8 |
0.082
|
Mouse |
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.082
|
Worm |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.082
|
Mouse |
|
|
regulation of removal of superoxide radicals
|
GO:2000121 |
4 |
0.081
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.081
|
Mouse |
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.079
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
17 |
0.078
|
Mouse |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.077
|
Worm |
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.075
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.075
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.075
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.074
|
Mouse |
|
|
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901028 |
7 |
0.074
|
|
|
|
regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
|
GO:1900739 |
3 |
0.073
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.073
|
Worm |
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.073
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.073
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.073
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.073
|
Worm |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.072
|
Zebrafish |
|
|
wound healing
|
GO:0042060 |
157 |
0.072
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
45 |
0.071
|
Mouse |
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.071
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.071
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.071
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.071
|
Zebrafish Mouse |
|
|
chromatin organization
|
GO:0006325 |
206 |
0.070
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.069
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.069
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.068
|
Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.068
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.068
|
Mouse |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.067
|
|
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
8 |
0.067
|
|
|
|
positive regulation of cellular carbohydrate metabolic process
|
GO:0010676 |
29 |
0.067
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
41 |
0.067
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.067
|
Mouse |
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.067
|
Mouse |
|
|
labyrinthine layer blood vessel development
|
GO:0060716 |
21 |
0.067
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.067
|
Mouse |
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.066
|
Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.066
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.066
|
Mouse |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.066
|
|
|
|
rna catabolic process
|
GO:0006401 |
29 |
0.066
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.065
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.065
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.065
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.065
|
|
|
|
removal of superoxide radicals
|
GO:0019430 |
12 |
0.064
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.064
|
Mouse |
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.064
|
Mouse |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.064
|
Worm |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.064
|
Worm |
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.064
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.064
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.063
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.063
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.062
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.062
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.062
|
|
|
|
apical constriction
|
GO:0003383 |
4 |
0.062
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.062
|
|
|
|
skin morphogenesis
|
GO:0043589 |
38 |
0.062
|
Mouse |
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.062
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
19 |
0.061
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.061
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.061
|
Mouse |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.061
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.061
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
38 |
0.061
|
Mouse |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.060
|
Worm |
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.060
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.060
|
Zebrafish |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.060
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.060
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.060
|
Mouse |
|
|
ossification
|
GO:0001503 |
216 |
0.060
|
Mouse |
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.060
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.060
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.059
|
Mouse |
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.059
|
Mouse |
|
|
gastrulation
|
GO:0007369 |
116 |
0.059
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.058
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.058
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.058
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.058
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.058
|
Mouse |
|
|
lipid transport
|
GO:0006869 |
98 |
0.057
|
|
|
|
regulation of neutrophil differentiation
|
GO:0045658 |
2 |
0.057
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.057
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.057
|
Worm |
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.057
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.057
|
Zebrafish Mouse |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.057
|
Zebrafish Mouse |
|
|
nephron development
|
GO:0072006 |
109 |
0.057
|
Mouse |
|
|
protein alkylation
|
GO:0008213 |
81 |
0.056
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.055
|
Mouse |
|
|
dna modification
|
GO:0006304 |
50 |
0.055
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.055
|
Worm |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.055
|
Zebrafish |
|
|
positive regulation of nuclear transcribed mrna poly a tail shortening
|
GO:0060213 |
4 |
0.055
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.054
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.054
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.054
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.054
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.054
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.054
|
|
|
|
cellular response to superoxide
|
GO:0071451 |
14 |
0.053
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.053
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.053
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.052
|
Mouse |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.052
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.052
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.051
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.050
|
Mouse |
|
|
negative regulation of stem cell differentiation
|
GO:2000737 |
14 |
0.050
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
24 |
0.050
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.050
|
Human Mouse |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.050
|
Worm |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.048
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.048
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.048
|
Worm |
|
|
regulation of stem cell differentiation
|
GO:2000736 |
50 |
0.048
|
|
|
|
viral life cycle
|
GO:0019058 |
36 |
0.048
|
Mouse |
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.047
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.047
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.047
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.047
|
Mouse |
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.047
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.047
|
Mouse |
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.047
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.047
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.047
|
Mouse |
|
|
protein import
|
GO:0017038 |
101 |
0.046
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.046
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.046
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.046
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.046
|
Zebrafish |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.045
|
Mouse |
|
|
regulation of microvillus assembly
|
GO:0032534 |
3 |
0.045
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.045
|
Mouse |
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
11 |
0.044
|
|
|
|
positive regulation of smooth muscle cell migration
|
GO:0014911 |
4 |
0.044
|
Mouse |
|
|
rna 3 end processing
|
GO:0031123 |
20 |
0.044
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.044
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.044
|
Mouse |
|
|
lung development
|
GO:0030324 |
164 |
0.044
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.044
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.044
|
Worm |
|
|
jnk cascade
|
GO:0007254 |
72 |
0.044
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.044
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.043
|
Mouse |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.043
|
Worm |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.043
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.043
|
|
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
22 |
0.043
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.043
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.043
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.042
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.042
|
Mouse |
|
|
regulation of microvillus organization
|
GO:0032530 |
3 |
0.042
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
2 |
0.042
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.042
|
Mouse |
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.042
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.042
|
|
|
|
regulation of protein acetylation
|
GO:1901983 |
22 |
0.041
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.041
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.041
|
Zebrafish |
|
|
myoblast differentiation
|
GO:0045445 |
52 |
0.041
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.041
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.041
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.040
|
Mouse |
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.040
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.040
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.040
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.040
|
Zebrafish Mouse |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.040
|
Worm |
|
|
rna processing
|
GO:0006396 |
105 |
0.040
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.040
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.040
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.039
|
Mouse |
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.039
|
Mouse |
|
|
lipid localization
|
GO:0010876 |
126 |
0.039
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.039
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.039
|
Mouse |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.039
|
|
|
|
negative regulation of tumor necrosis factor biosynthetic process
|
GO:0042536 |
1 |
0.038
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.038
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.038
|
Worm |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.038
|
Worm |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.038
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.038
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.038
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.037
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.037
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.037
|
Zebrafish Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.037
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.037
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.037
|
Mouse |
|
|
response to oxygen radical
|
GO:0000305 |
16 |
0.037
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.037
|
Zebrafish |
|
|
regulation of mrna stability
|
GO:0043488 |
23 |
0.037
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.037
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.037
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.037
|
Worm |
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.037
|
|
|
|
positive regulation of gene silencing by mirna
|
GO:2000637 |
1 |
0.036
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.036
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.036
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.036
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.036
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.036
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.036
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.035
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.035
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.035
|
Mouse |
|
|
endothelium development
|
GO:0003158 |
45 |
0.035
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.035
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.035
|
Zebrafish |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.035
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.034
|
Mouse |
|
|
response to drug
|
GO:0042493 |
75 |
0.034
|
Mouse |
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
66 |
0.034
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
34 |
0.034
|
Human |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.034
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.034
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.034
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.034
|
|
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.034
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.034
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.034
|
Worm |
|
|
positive regulation of carbohydrate metabolic process
|
GO:0045913 |
30 |
0.034
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.034
|
Mouse |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.034
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.034
|
Worm |
