|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.997
|
|
|
|
cellular response to peptidoglycan
|
GO:0071224 |
4 |
0.996
|
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.983
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.964
|
|
|
|
regulation of serotonin secretion
|
GO:0014062 |
3 |
0.956
|
|
|
|
serotonin secretion by mast cell
|
GO:0002552 |
1 |
0.955
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.946
|
|
|
|
negative regulation of mast cell degranulation
|
GO:0043305 |
4 |
0.939
|
|
|
|
histamine production involved in inflammatory response
|
GO:0002349 |
1 |
0.937
|
|
|
|
detection of molecule of bacterial origin
|
GO:0032490 |
2 |
0.926
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.918
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.910
|
|
|
|
detection of peptidoglycan
|
GO:0032499 |
1 |
0.898
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.884
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.881
|
|
|
|
detection of biotic stimulus
|
GO:0009595 |
10 |
0.857
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.855
|
|
|
|
histamine transport
|
GO:0051608 |
2 |
0.849
|
|
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.825
|
|
|
|
negative regulation of nik nf kappab signaling
|
GO:1901223 |
2 |
0.823
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.822
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.821
|
|
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
10 |
0.818
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.817
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.817
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.814
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.793
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.792
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.776
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.770
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.766
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.758
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.752
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.734
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.731
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.730
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.720
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.709
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.707
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.703
|
|
|
|
detection of lipoteichoic acid
|
GO:0070392 |
1 |
0.702
|
|
|
|
negative regulation of mast cell activation involved in immune response
|
GO:0033007 |
5 |
0.701
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.700
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.682
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.681
|
|
|
|
positive regulation of leukocyte degranulation
|
GO:0043302 |
10 |
0.675
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.670
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.662
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.624
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.615
|
|
|
|
negative regulation of mast cell activation
|
GO:0033004 |
6 |
0.610
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.609
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.582
|
|
|
|
histamine secretion by mast cell
|
GO:0002553 |
1 |
0.581
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.577
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.572
|
|
|
|
positive regulation of mast cell activation involved in immune response
|
GO:0033008 |
10 |
0.570
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.570
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.569
|
Rat |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.556
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.555
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.554
|
Rat |
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.542
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.541
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.541
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.538
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.537
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.528
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.520
|
|
|
|
response to peptidoglycan
|
GO:0032494 |
9 |
0.519
|
|
|
|
interleukin 18 production
|
GO:0032621 |
4 |
0.516
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.514
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.512
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.509
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.509
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.500
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.494
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.494
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.487
|
|
|
|
positive regulation of mast cell activation
|
GO:0033005 |
12 |
0.486
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.474
|
|
|
|
response to lipoteichoic acid
|
GO:0070391 |
6 |
0.473
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.468
|
|
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.468
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.465
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.462
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.460
|
|
|
|
serotonin secretion involved in inflammatory response
|
GO:0002442 |
4 |
0.457
|
|
|
|
serotonin production involved in inflammatory response
|
GO:0002351 |
4 |
0.456
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.444
|
|
|
|
detection of fungus
|
GO:0016046 |
2 |
0.443
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.441
|
|
|
|
innate immune response in mucosa
|
GO:0002227 |
3 |
0.438
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.435
|
|
|
|
cellular response to lipoteichoic acid
|
GO:0071223 |
6 |
0.434
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.433
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.432
|
|
|
|
neutrophil mediated immunity
|
GO:0002446 |
19 |
0.428
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.419
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.418
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.417
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.415
|
|
|
|
purinergic receptor signaling pathway
|
GO:0035587 |
7 |
0.413
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.412
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.404
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.399
|
|
|
|
monoamine transport
|
GO:0015844 |
33 |
0.399
|
|
|
|
positive regulation of toll like receptor 9 signaling pathway
|
GO:0034165 |
2 |
0.398
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.385
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.383
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.376
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.370
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.363
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.362
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.362
|
|
|
|
regulation of mucus secretion
|
GO:0070255 |
11 |
0.361
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.361
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.359
|
|
|
|
detection of external biotic stimulus
|
GO:0098581 |
9 |
0.357
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.356
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.355
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.344
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.332
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.331
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.321
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.317
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.314
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.300
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.298
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.295
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.295
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.295
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.289
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.287
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.286
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.283
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.280
|
|
|
|
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria
|
GO:0006965 |
1 |
0.275
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.275
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
14 |
0.274
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.270
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.259
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.255
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.252
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.249
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.247
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.246
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.242
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.240
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.239
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.238
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.238
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.237
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.237
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.235
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.233
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.229
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.224
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.224
|
|
|
|
immunoglobulin transcytosis in epithelial cells
|
GO:0002414 |
2 |
0.223
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.221
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.221
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.217
|
|
|
|
detection of lipopolysaccharide
|
GO:0032497 |
1 |
0.216
|
|
|
|
negative regulation of regulated secretory pathway
|
GO:1903306 |
7 |
0.214
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.213
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.213
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.212
|
|
|
|
negative regulation of toll like receptor 2 signaling pathway
|
GO:0034136 |
3 |
0.210
|
|
|
|
serotonin transport
|
GO:0006837 |
11 |
0.210
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.204
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.202
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.199
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.194
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.189
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.187
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.186
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.182
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.178
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.176
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.174
|
|
|
|
helper t cell enhancement of adaptive immune response
|
GO:0035397 |
1 |
0.174
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.173
|
|
|
|
toll like receptor 9 signaling pathway
|
GO:0034162 |
6 |
0.173
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.173
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.172
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.171
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.171
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.169
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.169
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.168
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.167
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.166
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.164
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.164
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.163
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.163
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.158
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.156
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.154
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.151
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.148
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.147
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.145
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.142
|
|
|
|
serotonin secretion
|
GO:0001820 |
8 |
0.141
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.139
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
12 |
0.139
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.139
|
|
|
|
regulation of interleukin 18 production
|
GO:0032661 |
3 |
0.133
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.128
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.126
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.126
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.126
|
|
|
|
azole transport
|
GO:0045117 |
6 |
0.125
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.125
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.124
|
|
|
|
histamine secretion
|
GO:0001821 |
1 |
0.124
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.124
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.123
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.120
|
|
|
|
regulation of acute inflammatory response to non antigenic stimulus
|
GO:0002877 |
2 |
0.120
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.118
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.118
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.117
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.116
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.116
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.116
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.115
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.113
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.113
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.113
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.112
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
30 |
0.111
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.111
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.110
|
|
|
|
neutrophil mediated killing of gram negative bacterium
|
GO:0070945 |
4 |
0.109
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.109
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.108
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.107
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.106
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.106
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
38 |
0.106
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.105
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.104
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.104
|
|
|
|
negative regulation of leukocyte degranulation
|
GO:0043301 |
7 |
0.102
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.102
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.102
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.101
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.101
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.101
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.099
|
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
6 |
0.099
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.098
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.098
|
|
|
|
mucosal immune response
|
GO:0002385 |
13 |
0.097
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.097
|
|
|
|
regulation of granulocyte macrophage colony stimulating factor production
|
GO:0032645 |
3 |
0.096
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.095
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.095
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.093
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.093
|
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.093
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.091
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.091
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.091
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.090
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.089
|
|
|
|
detection of bacterium
|
GO:0016045 |
7 |
0.087
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.086
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.086
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.086
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.085
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.085
|
|
|
|
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria
|
GO:0002816 |
1 |
0.084
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.084
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.084
|
|
|
|
positive regulation by symbiont of defense related host nitric oxide production
|
GO:0052347 |
1 |
0.082
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.082
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.082
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.081
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.081
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.081
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.080
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.079
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.078
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.077
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.077
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.077
|
|
|
|
negative regulation of interleukin 18 production
|
GO:0032701 |
1 |
0.075
|
|
|
|
negative regulation of t cell mediated immunity
|
GO:0002710 |
9 |
0.075
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.075
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.075
|
|
|
|
positive regulation of chemokine biosynthetic process
|
GO:0045080 |
6 |
0.075
|
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.075
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.074
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.074
|
|
|
|
regulation of macrophage activation
|
GO:0043030 |
17 |
0.074
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.073
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.071
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.071
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.071
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.070
|
|
|
|
negative regulation of interleukin 12 production
|
GO:0032695 |
10 |
0.069
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.069
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.069
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.069
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.068
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor production
|
GO:0032725 |
3 |
0.068
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.068
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.068
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.067
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.067
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.067
|
|
|
|
adenosine receptor signaling pathway
|
GO:0001973 |
5 |
0.066
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.066
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.066
|
|
|
|
positive regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002925 |
6 |
0.066
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.066
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.066
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.065
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.065
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.064
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.064
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.064
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.064
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.063
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.063
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.062
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.062
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
23 |
0.062
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.062
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.062
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.062
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.062
|
|
|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
10 |
0.062
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.061
|
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.061
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.061
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.061
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.061
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.061
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.060
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.059
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.059
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.058
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.058
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.057
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.057
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.057
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.056
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.056
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.056
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.055
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.055
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.054
|
|
|
|
histamine secretion involved in inflammatory response
|
GO:0002441 |
1 |
0.054
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.054
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.053
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
31 |
0.053
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.053
|
|
|
|
positive regulation of t helper 1 type immune response
|
GO:0002827 |
12 |
0.053
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.053
|
|
|
|
regulation of antimicrobial peptide biosynthetic process
|
GO:0002805 |
1 |
0.053
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.053
|
|
|
|
toll like receptor 7 signaling pathway
|
GO:0034154 |
4 |
0.053
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.052
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.052
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.052
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.052
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.051
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.051
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.051
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.051
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.051
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.051
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.050
|
|
|
|
detection of yeast
|
GO:0001879 |
2 |
0.050
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.050
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.050
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.049
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.049
|
|
|
|
mucus secretion
|
GO:0070254 |
12 |
0.049
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.049
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.049
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.048
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.048
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.047
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.047
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.047
|
|
|
|
positive regulation of mucus secretion
|
GO:0070257 |
8 |
0.047
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.046
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.046
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.046
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.046
|
|
|
|
endoderm development
|
GO:0007492 |
45 |
0.046
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.045
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.045
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.044
|
|
|
|
chemokine metabolic process
|
GO:0050755 |
10 |
0.044
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.044
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.044
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.044
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.044
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.044
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.044
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.043
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.042
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.042
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.042
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.042
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.041
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.041
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.041
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.041
|
|
|
|
biosynthetic process of antibacterial peptides active against gram positive bacteria
|
GO:0002815 |
1 |
0.041
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.041
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.041
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.040
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.040
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.040
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.040
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.040
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.040
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
30 |
0.039
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.039
|
|
|
|
interleukin 6 biosynthetic process
|
GO:0042226 |
12 |
0.038
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.038
|
|
|
|
detection of other organism
|
GO:0098543 |
8 |
0.038
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.038
|
|
|
|
modulation of growth of symbiont involved in interaction with host
|
GO:0044144 |
19 |
0.037
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.037
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.037
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.037
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.037
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.036
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.036
|
|
|
|
negative regulation of interleukin 2 production
|
GO:0032703 |
8 |
0.036
|
|
|
|
antibacterial peptide secretion
|
GO:0002779 |
1 |
0.036
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.036
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.035
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.035
|
|
|
|
positive regulation of interleukin 18 production
|
GO:0032741 |
2 |
0.035
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.034
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.034
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.034
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.033
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.033
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.033
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.033
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.033
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.033
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.033
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.033
|
|
|
|
inflammatory response to wounding
|
GO:0090594 |
4 |
0.032
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.032
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.032
|
|
|
|
granulocyte macrophage colony stimulating factor production
|
GO:0032604 |
3 |
0.032
|
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.032
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.032
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.032
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.032
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.032
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
8 |
0.031
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.031
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.031
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.031
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.031
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.031
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.031
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.031
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.031
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.031
|
|
|
|
positive regulation of antibacterial peptide production
|
GO:0002803 |
1 |
0.031
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
11 |
0.030
|
|
|
|
fc receptor mediated stimulatory signaling pathway
|
GO:0002431 |
4 |
0.030
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.030
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.030
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.030
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.030
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.030
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.030
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.030
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.030
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.029
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
20 |
0.029
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.029
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.029
|
|
|
|
regulation of nitric oxide synthase biosynthetic process
|
GO:0051769 |
7 |
0.028
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.028
|
|
|
|
macrophage inflammatory protein 1 alpha production
|
GO:0071608 |
1 |
0.028
|
|