Mus musculus

0 known processes

Mefv

Mediterranean fever

(Aliases: FMF,TRIM20,MGC124344,MGC124345,pyrin)

Mefv biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of mast cell activation GO:0033003 21 0.997
cellular response to peptidoglycan GO:0071224 4 0.996
negative regulation of serotonin secretion GO:0014063 2 0.983
mast cell activation involved in immune response GO:0002279 20 0.964
regulation of serotonin secretion GO:0014062 3 0.956
serotonin secretion by mast cell GO:0002552 1 0.955
regulation of mast cell activation involved in immune response GO:0033006 17 0.946
negative regulation of mast cell degranulation GO:0043305 4 0.939
histamine production involved in inflammatory response GO:0002349 1 0.937
detection of molecule of bacterial origin GO:0032490 2 0.926
regulation of inflammatory response GO:0050727 147 0.918
regulation of mast cell degranulation GO:0043304 16 0.910
detection of peptidoglycan GO:0032499 1 0.898
mast cell degranulation GO:0043303 19 0.884
mast cell activation GO:0045576 27 0.881
detection of biotic stimulus GO:0009595 10 0.857
regulation of leukocyte mediated immunity GO:0002703 104 0.855
histamine transport GO:0051608 2 0.849
activation of mapk activity involved in innate immune response GO:0035419 2 0.825
negative regulation of nik nf kappab signaling GO:1901223 2 0.823
mast cell mediated immunity GO:0002448 20 0.822
positive regulation of leukocyte mediated immunity GO:0002705 70 0.821
positive regulation of regulated secretory pathway GO:1903307 10 0.818
myeloid cell activation involved in immune response GO:0002275 34 0.817
regulation of cell activation GO:0050865 289 0.817
cytokine production GO:0001816 319 0.814
cellular response to lipopolysaccharide GO:0071222 77 0.793
regulation of defense response GO:0031347 233 0.792
leukocyte migration GO:0050900 124 0.776
positive regulation of immune effector process GO:0002699 107 0.770
positive regulation of defense response GO:0031349 124 0.766
myeloid leukocyte mediated immunity GO:0002444 42 0.758
positive regulation of cytokine production GO:0001819 174 0.752
regulation of cellular amino acid metabolic process GO:0006521 5 0.734
myeloid leukocyte activation GO:0002274 83 0.731
regulation of response to wounding GO:1903034 189 0.730
leukocyte mediated immunity GO:0002443 174 0.720
leukocyte degranulation GO:0043299 27 0.709
defense response to other organism GO:0098542 197 0.707
lysosome localization GO:0032418 20 0.703
detection of lipoteichoic acid GO:0070392 1 0.702
negative regulation of mast cell activation involved in immune response GO:0033007 5 0.701
cellular response to organonitrogen compound GO:0071417 145 0.700
inflammatory response GO:0006954 244 0.682
immune effector process GO:0002252 321 0.681
positive regulation of leukocyte degranulation GO:0043302 10 0.675
cellular response to molecule of bacterial origin GO:0071219 83 0.670
negative regulation of immune effector process GO:0002698 55 0.662
regulation of cytokine production GO:0001817 266 0.624
protein secretion GO:0009306 111 0.615
negative regulation of mast cell activation GO:0033004 6 0.610
nitrogen compound transport GO:0071705 271 0.609
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.582
histamine secretion by mast cell GO:0002553 1 0.581
cell activation involved in immune response GO:0002263 126 0.577
negative regulation of secretion GO:0051048 61 0.572
positive regulation of mast cell activation involved in immune response GO:0033008 10 0.570
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.570
response to lipopolysaccharide GO:0032496 128 0.569
Rat
positive regulation of secretion GO:0051047 130 0.556
leukocyte differentiation GO:0002521 342 0.555
response to molecule of bacterial origin GO:0002237 143 0.554
Rat
regulated secretory pathway GO:0045055 32 0.542
regulation of secretion GO:0051046 274 0.541
cation transport GO:0006812 399 0.541
cytokine secretion GO:0050663 72 0.538
regulation of establishment of protein localization GO:0070201 181 0.537
regulation of cellular ketone metabolic process GO:0010565 66 0.528
positive regulation of cell activation GO:0050867 158 0.520
response to peptidoglycan GO:0032494 9 0.519
interleukin 18 production GO:0032621 4 0.516
leukocyte activation involved in immune response GO:0002366 126 0.514
toll like receptor signaling pathway GO:0002224 38 0.512
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.509
regulation of cellular amine metabolic process GO:0033238 20 0.509
regulation of secretion by cell GO:1903530 249 0.500
positive regulation of cytokine secretion GO:0050715 41 0.494
regulation of protein secretion GO:0050708 82 0.494
regulation of cell motility GO:2000145 236 0.487
positive regulation of mast cell activation GO:0033005 12 0.486
peptidyl amino acid modification GO:0018193 336 0.474
response to lipoteichoic acid GO:0070391 6 0.473
regulation of cell migration GO:0030334 219 0.468
positive regulation of mast cell degranulation GO:0043306 10 0.468
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.465
regulation of body fluid levels GO:0050878 162 0.462
negative regulation of immune system process GO:0002683 209 0.460
serotonin secretion involved in inflammatory response GO:0002442 4 0.457
serotonin production involved in inflammatory response GO:0002351 4 0.456
regulation of interleukin 6 production GO:0032675 55 0.444
detection of fungus GO:0016046 2 0.443
positive regulation of intracellular transport GO:0032388 70 0.441
innate immune response in mucosa GO:0002227 3 0.438
cytokine mediated signaling pathway GO:0019221 115 0.435
cellular response to lipoteichoic acid GO:0071223 6 0.434
calcium mediated signaling GO:0019722 46 0.433
cellular amino acid metabolic process GO:0006520 103 0.432
neutrophil mediated immunity GO:0002446 19 0.428
inositol lipid mediated signaling GO:0048017 41 0.419
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.418
regulation of intracellular transport GO:0032386 159 0.417
regulation of vesicle mediated transport GO:0060627 139 0.415
purinergic receptor signaling pathway GO:0035587 7 0.413
body fluid secretion GO:0007589 53 0.412
negative regulation of leukocyte mediated immunity GO:0002704 29 0.404
negative regulation of cell activation GO:0050866 111 0.399
monoamine transport GO:0015844 33 0.399
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.398
adaptive immune response GO:0002250 155 0.385
regulation of protein transport GO:0051223 163 0.383
positive regulation of exocytosis GO:0045921 20 0.376
cellular ketone metabolic process GO:0042180 84 0.370
regulation of t cell proliferation GO:0042129 92 0.363
regulation of exocytosis GO:0017157 61 0.362
regulation of regulated secretory pathway GO:1903305 20 0.362
regulation of mucus secretion GO:0070255 11 0.361
regulation of chemokine production GO:0032642 30 0.361
cellular amine metabolic process GO:0044106 44 0.359
detection of external biotic stimulus GO:0098581 9 0.357
positive regulation of protein secretion GO:0050714 52 0.356
innate immune response activating signal transduction GO:0002758 50 0.355
myeloid dendritic cell activation GO:0001773 25 0.344
regulation of ion transport GO:0043269 215 0.332
regulation of cytokine secretion GO:0050707 61 0.331
osteoclast differentiation GO:0030316 62 0.321
positive regulation of protein transport GO:0051222 93 0.317
negative regulation of defense response GO:0031348 77 0.314
innate immune response GO:0045087 157 0.300
regulation of protein kinase activity GO:0045859 232 0.298
g protein coupled receptor signaling pathway GO:0007186 243 0.295
regulation of leukocyte degranulation GO:0043300 20 0.295
cellular response to lipid GO:0071396 145 0.295
positive regulation of calcium mediated signaling GO:0050850 15 0.289
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.287
regulation of t cell activation GO:0050863 170 0.286
defense response to bacterium GO:0042742 119 0.283
exocytosis GO:0006887 121 0.280
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 1 0.275
regulation of hormone levels GO:0010817 211 0.275
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.274
negative regulation of lymphocyte activation GO:0051250 91 0.270
positive regulation of phagocytosis GO:0050766 26 0.259
phosphatidylinositol mediated signaling GO:0048015 41 0.255
i kappab kinase nf kappab signaling GO:0007249 85 0.252
peptidyl tyrosine phosphorylation GO:0018108 143 0.249
regulation of acute inflammatory response GO:0002673 27 0.247
positive regulation of cytokine biosynthetic process GO:0042108 40 0.246
hormone secretion GO:0046879 128 0.242
regulation of toll like receptor signaling pathway GO:0034121 20 0.240
t cell proliferation GO:0042098 120 0.239
negative regulation of secretion by cell GO:1903531 54 0.238
immunoglobulin mediated immune response GO:0016064 69 0.238
immune response activating signal transduction GO:0002757 116 0.237
cell chemotaxis GO:0060326 81 0.237
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.235
regulation of immunoglobulin mediated immune response GO:0002889 37 0.233
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.229
regulation of transferase activity GO:0051338 263 0.224
myeloid cell differentiation GO:0030099 233 0.224
immunoglobulin transcytosis in epithelial cells GO:0002414 2 0.223
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.221
positive regulation of inflammatory response GO:0050729 47 0.221
regulation of lymphocyte mediated immunity GO:0002706 84 0.217
detection of lipopolysaccharide GO:0032497 1 0.216
negative regulation of regulated secretory pathway GO:1903306 7 0.214
positive regulation of secretion by cell GO:1903532 114 0.213
negative regulation of inflammatory response GO:0050728 61 0.213
t cell activation GO:0042110 289 0.212
negative regulation of toll like receptor 2 signaling pathway GO:0034136 3 0.210
serotonin transport GO:0006837 11 0.210
regulation of phagocytosis GO:0050764 33 0.204
positive regulation of cellular amine metabolic process GO:0033240 5 0.202
positive regulation of adaptive immune response GO:0002821 61 0.199
chemotaxis GO:0006935 247 0.194
positive regulation of cell migration GO:0030335 109 0.189
peptidyl tyrosine modification GO:0018212 145 0.187
defense response to gram negative bacterium GO:0050829 28 0.186
organic hydroxy compound transport GO:0015850 93 0.182
endocytosis GO:0006897 168 0.178
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.176
regulation of b cell mediated immunity GO:0002712 37 0.174
helper t cell enhancement of adaptive immune response GO:0035397 1 0.174
t cell mediated immunity GO:0002456 50 0.173
toll like receptor 9 signaling pathway GO:0034162 6 0.173
regulation of protein localization GO:0032880 231 0.173
antibacterial peptide production GO:0002778 2 0.172
regulation of innate immune response GO:0045088 91 0.171
positive regulation of innate immune response GO:0045089 80 0.171
organelle localization GO:0051640 179 0.169
positive regulation of cell death GO:0010942 224 0.169
chemokine production GO:0032602 34 0.168
second messenger mediated signaling GO:0019932 73 0.167
production of molecular mediator involved in inflammatory response GO:0002532 21 0.166
antibacterial peptide biosynthetic process GO:0002780 2 0.164
amine metabolic process GO:0009308 45 0.164
cellular response to cytokine stimulus GO:0071345 189 0.163
syncytium formation by plasma membrane fusion GO:0000768 42 0.163
interleukin 6 production GO:0032635 58 0.158
leukocyte chemotaxis GO:0030595 69 0.156
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.154
myeloid leukocyte differentiation GO:0002573 119 0.151
granulocyte migration GO:0097530 43 0.148
neutrophil chemotaxis GO:0030593 36 0.147
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.145
negative regulation of cellular protein metabolic process GO:0032269 247 0.142
serotonin secretion GO:0001820 8 0.141
t helper 1 type immune response GO:0042088 25 0.139
negative regulation of exocytosis GO:0045920 12 0.139
regulation of interferon gamma production GO:0032649 57 0.139
regulation of interleukin 18 production GO:0032661 3 0.133
production of molecular mediator of immune response GO:0002440 103 0.128
acute inflammatory response GO:0002526 41 0.126
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.126
regulation of cytokine biosynthetic process GO:0042035 59 0.126
azole transport GO:0045117 6 0.125
positive regulation of lymphocyte activation GO:0051251 140 0.125
b cell mediated immunity GO:0019724 71 0.124
histamine secretion GO:0001821 1 0.124
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.124
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.123
response to peptide GO:1901652 136 0.120
regulation of acute inflammatory response to non antigenic stimulus GO:0002877 2 0.120
antimicrobial peptide production GO:0002775 2 0.118
positive regulation of homeostatic process GO:0032846 64 0.118
cytokine biosynthetic process GO:0042089 68 0.117
positive regulation of protein phosphorylation GO:0001934 242 0.116
regulation of kinase activity GO:0043549 249 0.116
negative regulation of growth GO:0045926 99 0.116
activation of mapk activity GO:0000187 59 0.115
activation of immune response GO:0002253 138 0.113
negative regulation of adaptive immune response GO:0002820 25 0.113
positive regulation of kinase activity GO:0033674 155 0.113
cellular homeostasis GO:0019725 240 0.112
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.111
regulation of lymphocyte proliferation GO:0050670 117 0.111
positive regulation of leukocyte differentiation GO:1902107 86 0.110
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.109
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.109
positive regulation of response to wounding GO:1903036 66 0.108
lymphocyte mediated immunity GO:0002449 139 0.107
regulation of t cell differentiation GO:0045580 83 0.106
lymphocyte proliferation GO:0046651 164 0.106
negative regulation of intracellular transport GO:0032387 38 0.106
regulation of lymphocyte activation GO:0051249 240 0.105
immune response regulating signaling pathway GO:0002764 125 0.104
cellular response to biotic stimulus GO:0071216 92 0.104
negative regulation of leukocyte degranulation GO:0043301 7 0.102
negative regulation of phosphorylation GO:0042326 166 0.102
regulation of defense response to bacterium GO:1900424 3 0.102
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.101
defense response to gram positive bacterium GO:0050830 50 0.101
cellular calcium ion homeostasis GO:0006874 119 0.101
regulation of stress activated mapk cascade GO:0032872 69 0.099
toll like receptor 2 signaling pathway GO:0034134 6 0.099
reactive oxygen species metabolic process GO:0072593 84 0.098
regulation of adaptive immune response GO:0002819 90 0.098
mucosal immune response GO:0002385 13 0.097
positive regulation of transferase activity GO:0051347 167 0.097
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 3 0.096
activation of innate immune response GO:0002218 56 0.095
wound healing GO:0042060 157 0.095
cytokine metabolic process GO:0042107 71 0.093
positive regulation of t cell activation GO:0050870 101 0.093
organ or tissue specific immune response GO:0002251 13 0.093
granulocyte chemotaxis GO:0071621 39 0.091
negative regulation of t cell activation GO:0050868 65 0.091
tumor necrosis factor production GO:0032640 50 0.091
positive regulation of protein kinase activity GO:0045860 144 0.090
regulation of b cell proliferation GO:0030888 39 0.089
detection of bacterium GO:0016045 7 0.087
negative regulation of phosphate metabolic process GO:0045936 184 0.086
negative regulation of cell proliferation GO:0008285 296 0.086
regulation of lymphocyte differentiation GO:0045619 107 0.086
regulation of antibacterial peptide production GO:0002786 1 0.085
positive regulation of protein modification process GO:0031401 299 0.085
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 1 0.084
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.084
immunoglobulin production GO:0002377 73 0.084
positive regulation by symbiont of defense related host nitric oxide production GO:0052347 1 0.082
jak stat cascade GO:0007259 42 0.082
regulation of map kinase activity GO:0043405 120 0.082
protein modification by small protein conjugation GO:0032446 187 0.081
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.081
protein ubiquitination GO:0016567 171 0.081
mapk cascade GO:0000165 281 0.080
erk1 and erk2 cascade GO:0070371 77 0.079
metal ion homeostasis GO:0055065 189 0.078
homeostasis of number of cells GO:0048872 210 0.077
cell type specific apoptotic process GO:0097285 268 0.077
regulation of cytoplasmic transport GO:1903649 112 0.077
negative regulation of interleukin 18 production GO:0032701 1 0.075
negative regulation of t cell mediated immunity GO:0002710 9 0.075
alpha beta t cell activation GO:0046631 91 0.075
detection of stimulus GO:0051606 84 0.075
positive regulation of chemokine biosynthetic process GO:0045080 6 0.075
humoral immune response mediated by circulating immunoglobulin GO:0002455 14 0.075
amide transport GO:0042886 138 0.074
positive regulation of stress activated mapk cascade GO:0032874 48 0.074
regulation of macrophage activation GO:0043030 17 0.074
positive regulation of cellular catabolic process GO:0031331 148 0.073
negative regulation of phosphorus metabolic process GO:0010563 184 0.071
neutrophil migration GO:1990266 37 0.071
b cell activation GO:0042113 161 0.071
regulation of erk1 and erk2 cascade GO:0070372 71 0.070
negative regulation of interleukin 12 production GO:0032695 10 0.069
response to organonitrogen compound GO:0010243 246 0.069
ion transmembrane transport GO:0034220 361 0.069
cellular response to acid chemical GO:0071229 68 0.069
regulation of epithelial cell proliferation GO:0050678 141 0.068
positive regulation of granulocyte macrophage colony stimulating factor production GO:0032725 3 0.068
protein modification by small protein conjugation or removal GO:0070647 207 0.068
regulation of proteolysis GO:0030162 164 0.068
negative regulation of cellular amine metabolic process GO:0033239 1 0.067
leukocyte proliferation GO:0070661 172 0.067
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.067
adenosine receptor signaling pathway GO:0001973 5 0.066
negative regulation of protein phosphorylation GO:0001933 126 0.066
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.066
positive regulation of humoral immune response mediated by circulating immunoglobulin GO:0002925 6 0.066
positive regulation of mapk cascade GO:0043410 170 0.066
myeloid leukocyte migration GO:0097529 57 0.066
negative regulation of b cell proliferation GO:0030889 13 0.065
pallium development GO:0021543 120 0.065
negative regulation of response to wounding GO:1903035 77 0.064
peptide transport GO:0015833 133 0.064
t cell differentiation GO:0030217 174 0.064
cellular amide metabolic process GO:0043603 58 0.064
defense response to virus GO:0051607 68 0.063
cellular divalent inorganic cation homeostasis GO:0072503 127 0.063
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.062
negative regulation of molecular function GO:0044092 258 0.062
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.062
positive regulation of t cell differentiation GO:0045582 52 0.062
negative regulation of leukocyte differentiation GO:1902106 51 0.062
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.062
t cell receptor signaling pathway GO:0050852 46 0.062
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 10 0.062
regulation of t helper 1 type immune response GO:0002825 17 0.061
macrophage activation GO:0042116 27 0.061
negative regulation of t cell proliferation GO:0042130 38 0.061
regulation of multi organism process GO:0043900 111 0.061
positive regulation of acute inflammatory response GO:0002675 16 0.061
cellular chemical homeostasis GO:0055082 215 0.061
positive regulation of map kinase activity GO:0043406 84 0.060
cellular metal ion homeostasis GO:0006875 151 0.059
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.059
mature dendritic cell differentiation GO:0097029 3 0.058
positive regulation of cell motility GO:2000147 116 0.058
regulation of calcium mediated signaling GO:0050848 19 0.057
regulation of interleukin 10 secretion GO:2001179 4 0.057
antimicrobial peptide biosynthetic process GO:0002777 2 0.057
regulation of peptide transport GO:0090087 91 0.056
interferon gamma production GO:0032609 67 0.056
pattern recognition receptor signaling pathway GO:0002221 47 0.056
embryonic placenta development GO:0001892 98 0.055
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.055
positive regulation of endocytosis GO:0045807 42 0.054
histamine secretion involved in inflammatory response GO:0002441 1 0.054
t cell activation involved in immune response GO:0002286 43 0.054
calcium ion homeostasis GO:0055074 127 0.053
cerebral cortex radially oriented cell migration GO:0021799 31 0.053
positive regulation of defense response to bacterium GO:1900426 1 0.053
positive regulation of t helper 1 type immune response GO:0002827 12 0.053
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.053
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.053
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.053
toll like receptor 7 signaling pathway GO:0034154 4 0.053
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.052
cerebral cortex development GO:0021987 86 0.052
t helper cell differentiation GO:0042093 28 0.052
divalent inorganic cation homeostasis GO:0072507 138 0.052
negative regulation of protein modification process GO:0031400 163 0.051
negative regulation of lymphocyte proliferation GO:0050672 45 0.051
inflammatory response to antigenic stimulus GO:0002437 30 0.051
stem cell differentiation GO:0048863 268 0.051
positive regulation of programmed cell death GO:0043068 218 0.051
positive regulation of t cell proliferation GO:0042102 52 0.051
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.050
detection of yeast GO:0001879 2 0.050
regulation of leukocyte proliferation GO:0070663 121 0.050
cytokine production involved in immune response GO:0002367 34 0.050
organic hydroxy compound metabolic process GO:1901615 203 0.049
sequestering of calcium ion GO:0051208 18 0.049
mucus secretion GO:0070254 12 0.049
regulation of hydrolase activity GO:0051336 246 0.049
positive regulation of interferon gamma production GO:0032729 39 0.049
regulation of tumor necrosis factor production GO:0032680 49 0.048
lymphocyte activation involved in immune response GO:0002285 93 0.048
response to acid chemical GO:0001101 111 0.047
regulation of antimicrobial humoral response GO:0002759 3 0.047
regulation of mapk cascade GO:0043408 248 0.047
positive regulation of mucus secretion GO:0070257 8 0.047
tyrosine phosphorylation of stat protein GO:0007260 23 0.046
cation homeostasis GO:0055080 212 0.046
regulation of protein serine threonine kinase activity GO:0071900 157 0.046
cellular response to amino acid stimulus GO:0071230 29 0.046
endoderm development GO:0007492 45 0.046
forebrain development GO:0030900 302 0.045
positive regulation of interleukin 6 production GO:0032755 37 0.045
somatic diversification of immune receptors GO:0002200 53 0.044
chemokine metabolic process GO:0050755 10 0.044
negative regulation of cytokine production GO:0001818 84 0.044
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.044
defense response to protozoan GO:0042832 25 0.044
muscle cell differentiation GO:0042692 261 0.044
response to organic cyclic compound GO:0014070 198 0.044
negative regulation of cellular component organization GO:0051129 194 0.044
response to growth factor GO:0070848 198 0.043
regulation of leukocyte apoptotic process GO:2000106 56 0.042
telencephalon cell migration GO:0022029 55 0.042
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.042
cytosolic calcium ion homeostasis GO:0051480 70 0.042
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.041
epidermis development GO:0008544 187 0.041
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.041
phagocytosis GO:0006909 66 0.041
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 1 0.041
negative regulation of mapk cascade GO:0043409 65 0.041
regulation of homeostatic process GO:0032844 182 0.041
stress activated mapk cascade GO:0051403 80 0.040
germ cell development GO:0007281 185 0.040
regulation of hormone secretion GO:0046883 88 0.040
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.040
stem cell maintenance GO:0019827 130 0.040
regulation of endocytosis GO:0030100 69 0.040
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.039
peptide secretion GO:0002790 114 0.039
interleukin 6 biosynthetic process GO:0042226 12 0.038
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.038
detection of other organism GO:0098543 8 0.038
olfactory learning GO:0008355 2 0.038
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.037
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.037
nuclear transport GO:0051169 139 0.037
antigen receptor mediated signaling pathway GO:0050851 64 0.037
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.037
regulation of immunoglobulin production GO:0002637 42 0.036
anion transport GO:0006820 177 0.036
negative regulation of interleukin 2 production GO:0032703 8 0.036
antibacterial peptide secretion GO:0002779 1 0.036
positive regulation of jnk cascade GO:0046330 46 0.036
maintenance of location GO:0051235 89 0.035
regulation of chemotaxis GO:0050920 53 0.035
positive regulation of interleukin 18 production GO:0032741 2 0.035
histone modification GO:0016570 159 0.034
mucopolysaccharide metabolic process GO:1903510 25 0.034
fertilization GO:0009566 127 0.034
inorganic cation transmembrane transport GO:0098662 207 0.033
inflammatory cell apoptotic process GO:0006925 11 0.033
positive regulation of ion transport GO:0043270 65 0.033
protein catabolic process GO:0030163 221 0.033
organic acid transport GO:0015849 101 0.033
multicellular organismal homeostasis GO:0048871 164 0.033
syncytium formation GO:0006949 43 0.033
positive regulation of antimicrobial humoral response GO:0002760 2 0.033
inflammatory response to wounding GO:0090594 4 0.032
positive regulation of epithelial cell proliferation GO:0050679 68 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
granulocyte macrophage colony stimulating factor production GO:0032604 3 0.032
regulation of antibacterial peptide biosynthetic process GO:0002808 1 0.032
cellular response to growth factor stimulus GO:0071363 197 0.032
regulation of jak stat cascade GO:0046425 34 0.032
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
regulation of tyrosine phosphorylation of stat5 protein GO:0042522 8 0.031
multi multicellular organism process GO:0044706 109 0.031
positive regulation of tumor necrosis factor production GO:0032760 30 0.031
neuron death GO:0070997 154 0.031
regulation of cellular component biogenesis GO:0044087 181 0.031
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.031
negative regulation of multi organism process GO:0043901 68 0.031
response to radiation GO:0009314 165 0.031
insulin secretion GO:0030073 89 0.031
positive regulation of antibacterial peptide production GO:0002803 1 0.031
positive regulation of humoral immune response GO:0002922 11 0.030
fc receptor mediated stimulatory signaling pathway GO:0002431 4 0.030
regulation of protein kinase b signaling GO:0051896 56 0.030
negative regulation of leukocyte proliferation GO:0070664 46 0.030
small gtpase mediated signal transduction GO:0007264 97 0.030
chromatin modification GO:0016568 187 0.030
regulation of lymphocyte apoptotic process GO:0070228 41 0.030
response to light stimulus GO:0009416 135 0.030
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.030
regulation of leukocyte differentiation GO:1902105 159 0.030
positive regulation of cell development GO:0010720 237 0.029
negative regulation of protein secretion GO:0050709 20 0.029
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
regulation of nitric oxide synthase biosynthetic process GO:0051769 7 0.028
divalent metal ion transport GO:0070838 172 0.028
macrophage inflammatory protein 1 alpha production GO:0071608 1 0.028

Mefv disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease by infectious agent DOID:0050117 0 0.059
cancer DOID:162 0 0.057
disease of cellular proliferation DOID:14566 0 0.057
organ system cancer DOID:0050686 0 0.057
acquired immunodeficiency syndrome DOID:635 0 0.053
viral infectious disease DOID:934 0 0.053
human immunodeficiency virus infectious disease DOID:526 0 0.053