Mus musculus

215 known processes

Megf8

multiple EGF-like-domains 8

(Aliases: Egfl4,mKIAA0817,AW049492)

Megf8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
left right pattern formation GO:0060972 23 0.999
intraciliary retrograde transport GO:0035721 3 0.992
embryonic heart tube left right pattern formation GO:0060971 5 0.980
neural tube development GO:0021915 160 0.960
regionalization GO:0003002 337 0.893
epithelial tube morphogenesis GO:0060562 303 0.862
embryonic limb morphogenesis GO:0030326 126 0.859
sperm ejaculation GO:0042713 1 0.847
epithelial tube formation GO:0072175 130 0.834
primary neural tube formation GO:0014020 95 0.809
smoothened signaling pathway GO:0007224 105 0.802
neural tube closure GO:0001843 90 0.763
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.679
morphogenesis of embryonic epithelium GO:0016331 159 0.673
microtubule based movement GO:0007018 84 0.645
embryonic heart tube development GO:0035050 65 0.637
microtubule based process GO:0007017 236 0.493
limb morphogenesis GO:0035108 149 0.440
neural tube formation GO:0001841 108 0.434
tube closure GO:0060606 91 0.434
embryonic epithelial tube formation GO:0001838 130 0.415
embryonic digit morphogenesis GO:0042733 56 0.374
cilium assembly GO:0042384 81 0.363
cilium movement GO:0003341 28 0.357
nonmotile primary cilium assembly GO:0035058 8 0.332
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.301
sensory organ morphogenesis GO:0090596 242 0.300
intraciliary transport GO:0042073 9 0.293
determination of heart left right asymmetry GO:0061371 48 0.271
embryonic appendage morphogenesis GO:0035113 126 0.264
mesendoderm development GO:0048382 3 0.252
appendage morphogenesis GO:0035107 149 0.247
prechordal plate formation GO:0021501 1 0.237
dorsal ventral neural tube patterning GO:0021904 28 0.221
determination of left right symmetry GO:0007368 80 0.218
spinal cord development GO:0021510 81 0.214
regulation of smoothened signaling pathway GO:0008589 58 0.211
lung development GO:0030324 164 0.205
insemination GO:0007320 6 0.199
negative regulation of smoothened signaling pathway GO:0045879 25 0.197
determination of left right asymmetry in nervous system GO:0035545 1 0.197
detection of nodal flow GO:0003127 2 0.194
telencephalon development GO:0021537 186 0.189
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 12 0.188
sensory perception of sour taste GO:0050915 2 0.175
floor plate morphogenesis GO:0033505 3 0.161
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity GO:0031585 2 0.159
body morphogenesis GO:0010171 45 0.150
left right axis specification GO:0070986 13 0.148
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.147
insulin receptor signaling pathway GO:0008286 49 0.147
embryonic heart tube morphogenesis GO:0003143 51 0.146
nucleoside phosphate metabolic process GO:0006753 338 0.145
microtubule based transport GO:0010970 50 0.144
tube formation GO:0035148 140 0.142
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.140
cellular response to acidic ph GO:0071468 4 0.139
positive regulation of protein phosphorylation GO:0001934 242 0.138
cilium morphogenesis GO:0060271 102 0.135
epithelial cell proliferation GO:0050673 174 0.134
heart morphogenesis GO:0003007 178 0.133
respiratory tube development GO:0030323 167 0.130
camera type eye development GO:0043010 266 0.129
gastrulation GO:0007369 116 0.128
Human
muscle system process GO:0003012 141 0.124
digestive system development GO:0055123 200 0.123
ventricular system development GO:0021591 27 0.116
spinal cord dorsal ventral patterning GO:0021513 23 0.116
regulation of kinase activity GO:0043549 249 0.115
negative regulation of cation channel activity GO:2001258 1 0.114
purine containing compound metabolic process GO:0072521 311 0.112
male gamete generation GO:0048232 285 0.109
membrane organization GO:0061024 245 0.109
spinal cord patterning GO:0021511 25 0.109
regulation of cellular catabolic process GO:0031329 242 0.109
cardiac chamber morphogenesis GO:0003206 93 0.102
digestive tract development GO:0048565 190 0.101
negative regulation of calcium ion transmembrane transporter activity GO:1901020 1 0.100
response to fluid shear stress GO:0034405 7 0.100
negative regulation of nervous system development GO:0051961 156 0.100
limb development GO:0060173 166 0.098
establishment of protein localization to organelle GO:0072594 118 0.093
cellular response to insulin stimulus GO:0032869 78 0.092
positive regulation of transferase activity GO:0051347 167 0.091
inorganic cation transmembrane transport GO:0098662 207 0.089
protein localization to membrane GO:0072657 108 0.089
proximal convoluted tubule development GO:0072019 1 0.087
metanephric ascending thin limb development GO:0072218 2 0.087
fertilization GO:0009566 127 0.085
respiratory system development GO:0060541 190 0.084
activin receptor signaling pathway GO:0032924 18 0.083
protein localization to nonmotile primary cilium GO:0097499 1 0.081
detection of chemical stimulus involved in sensory perception GO:0050907 10 0.080
skeletal system morphogenesis GO:0048705 203 0.080
regulation of microtubule based process GO:0032886 52 0.080
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.080
left lung morphogenesis GO:0060460 3 0.079
positive regulation of protein modification process GO:0031401 299 0.079
negative regulation of ryanodine sensitive calcium release channel activity GO:0060315 1 0.077
cardiocyte differentiation GO:0035051 87 0.075
nucleotide metabolic process GO:0009117 332 0.075
ribonucleotide metabolic process GO:0009259 291 0.075
positive regulation of kinase activity GO:0033674 155 0.073
spleen development GO:0048536 39 0.072
mitotic cell cycle process GO:1903047 159 0.071
regulation of insulin receptor signaling pathway GO:0046626 21 0.070
rho protein signal transduction GO:0007266 32 0.069
bone development GO:0060348 120 0.069
Human
cardiac chamber development GO:0003205 108 0.069
neural tube patterning GO:0021532 43 0.069
cell substrate adhesion GO:0031589 130 0.068
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.068
metanephric loop of henle development GO:0072236 4 0.066
ribose phosphate metabolic process GO:0019693 291 0.065
venous blood vessel development GO:0060841 13 0.064
positive regulation of hydrolase activity GO:0051345 148 0.064
cytoskeleton dependent intracellular transport GO:0030705 50 0.064
purine nucleoside catabolic process GO:0006152 205 0.063
cellular response to growth factor stimulus GO:0071363 197 0.063
left lung development GO:0060459 4 0.063
liver development GO:0001889 66 0.059
reactive oxygen species biosynthetic process GO:1903409 8 0.059
regulation of ossification GO:0030278 112 0.059
cellular response to fluid shear stress GO:0071498 4 0.058
muscle tissue development GO:0060537 308 0.057
cell matrix adhesion GO:0007160 68 0.057
nucleobase containing small molecule metabolic process GO:0055086 352 0.056
appendage development GO:0048736 166 0.056
regulation of protein kinase activity GO:0045859 232 0.055
axial mesodermal cell fate specification GO:0048327 1 0.055
regulation of organelle organization GO:0033043 289 0.055
cellular component assembly involved in morphogenesis GO:0010927 139 0.055
striated muscle tissue development GO:0014706 293 0.054
single fertilization GO:0007338 82 0.054
glycosyl compound catabolic process GO:1901658 206 0.054
regulation of muscle system process GO:0090257 80 0.054
cation homeostasis GO:0055080 212 0.054
kidney development GO:0001822 213 0.053
positive regulation of ras gtpase activity GO:0032320 65 0.053
regulation of mitotic spindle organization GO:0060236 2 0.052
inorganic ion transmembrane transport GO:0098660 234 0.052
regulation of purine nucleotide metabolic process GO:1900542 169 0.052
renal system development GO:0072001 225 0.052
protein localization to organelle GO:0033365 185 0.051
regulation of epithelial cell proliferation GO:0050678 141 0.051
cation transmembrane transport GO:0098655 266 0.051
reactive oxygen species metabolic process GO:0072593 84 0.051
purine nucleotide metabolic process GO:0006163 302 0.051
ascending thin limb development GO:0072021 2 0.051
mitotic cell cycle GO:0000278 195 0.050
regulation of nucleoside metabolic process GO:0009118 130 0.050
adrenal cortex formation GO:0035802 2 0.050
skeletal system development GO:0001501 356 0.047
connective tissue development GO:0061448 179 0.047
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.046
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.046
sodium ion transmembrane transport GO:0035725 49 0.046
cardiac septum development GO:0003279 59 0.046
response to insulin GO:0032868 100 0.046
cardiac muscle tissue development GO:0048738 130 0.045
negative regulation of calcium ion transmembrane transport GO:1903170 1 0.045
regulation of spindle organization GO:0090224 2 0.043
reactive nitrogen species metabolic process GO:2001057 0 0.043
protein targeting GO:0006605 143 0.043
exocytosis GO:0006887 121 0.043
mesenchyme development GO:0060485 152 0.042
metanephric collecting duct development GO:0072205 7 0.041
striated muscle contraction GO:0006941 45 0.041
protein ubiquitination GO:0016567 171 0.041
purine containing compound catabolic process GO:0072523 213 0.041
positive regulation of peroxisome proliferator activated receptor signaling pathway GO:0035360 2 0.041
calcium ion dependent exocytosis GO:0017156 35 0.041
regulation of activin receptor signaling pathway GO:0032925 10 0.040
nucleotide catabolic process GO:0009166 217 0.040
metal ion homeostasis GO:0055065 189 0.040
actin cytoskeleton organization GO:0030036 220 0.040
purine ribonucleotide metabolic process GO:0009150 290 0.040
regulation of cytoskeleton organization GO:0051493 122 0.040
development of primary sexual characteristics GO:0045137 143 0.039
response to parathyroid hormone GO:0071107 3 0.039
multi multicellular organism process GO:0044706 109 0.038
Worm
mating GO:0007618 27 0.038
macromolecule catabolic process GO:0009057 281 0.038
cardiac muscle cell differentiation GO:0055007 69 0.038
cardiac septum morphogenesis GO:0060411 46 0.037
cardiac ventricle development GO:0003231 83 0.037
cell adhesion GO:0007155 329 0.037
g1 s transition of mitotic cell cycle GO:0000082 57 0.037
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.036
positive regulation of protein kinase activity GO:0045860 144 0.036
organelle assembly GO:0070925 177 0.036
negative regulation of cell proliferation GO:0008285 296 0.036
calcium ion transmembrane transport GO:0070588 85 0.036
rab protein signal transduction GO:0032482 1 0.035
signal transduction downstream of smoothened GO:0007227 4 0.034
stem cell development GO:0048864 219 0.034
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.034
negative regulation of prostatic bud formation GO:0060686 4 0.034
transmembrane transport GO:0055085 412 0.034
small gtpase mediated signal transduction GO:0007264 97 0.034
cellular amino acid metabolic process GO:0006520 103 0.034
response to light stimulus GO:0009416 135 0.034
metanephric part of ureteric bud development GO:0035502 2 0.034
regulation of intracellular transport GO:0032386 159 0.034
protein modification by small protein conjugation GO:0032446 187 0.033
response to peptide hormone GO:0043434 127 0.033
segmentation GO:0035282 93 0.033
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.033
regulation of protein targeting GO:1903533 61 0.032
protein import GO:0017038 101 0.032
metanephros morphogenesis GO:0003338 24 0.032
regulation of cytoplasmic transport GO:1903649 112 0.032
regulation of establishment of protein localization GO:0070201 181 0.031
regulation of cell adhesion GO:0030155 154 0.031
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
embryonic placenta development GO:0001892 98 0.031
heart formation GO:0060914 16 0.030
embryonic skeletal system development GO:0048706 120 0.030
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.030
male gonad development GO:0008584 88 0.030
artery development GO:0060840 53 0.030
maintenance of location GO:0051235 89 0.029
plasma membrane organization GO:0007009 90 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.029
regulation of receptor activity GO:0010469 41 0.029
pancreas development GO:0031016 57 0.028
gonad development GO:0008406 141 0.028
cellular metal ion homeostasis GO:0006875 151 0.028
dorsal ventral axon guidance GO:0033563 3 0.028
determination of digestive tract left right asymmetry GO:0071907 1 0.028
protein modification by small protein conjugation or removal GO:0070647 207 0.028
regulation of cell cycle process GO:0010564 160 0.028
response to acid chemical GO:0001101 111 0.028
ameboidal type cell migration GO:0001667 128 0.028
Human
forebrain development GO:0030900 302 0.028
development of primary male sexual characteristics GO:0046546 88 0.028
branching morphogenesis of an epithelial tube GO:0048754 159 0.027
positive regulation of nucleotide catabolic process GO:0030813 88 0.027
regulation of intracellular protein transport GO:0033157 82 0.027
bmp signaling pathway GO:0030509 93 0.027
regulation of nucleotide metabolic process GO:0006140 169 0.027
vagus nerve development GO:0021564 3 0.027
intracellular receptor signaling pathway GO:0030522 74 0.027
positive regulation of gtp catabolic process GO:0033126 85 0.027
hypothalamus cell migration GO:0021855 5 0.027
divalent inorganic cation transport GO:0072511 178 0.026
detection of stimulus involved in sensory perception GO:0050906 44 0.026
sequestering of calcium ion GO:0051208 18 0.026
positive regulation of cell cycle GO:0045787 92 0.026
negative regulation of protein localization to nucleus GO:1900181 23 0.026
regulation of exocytosis GO:0017157 61 0.026
regulation of secretion GO:0051046 274 0.026
acrosome reaction GO:0007340 19 0.026
innate immune response GO:0045087 157 0.026
urogenital system development GO:0001655 261 0.026
retrograde transport endosome to golgi GO:0042147 2 0.026
spermatogenesis GO:0007283 284 0.026
protein polyubiquitination GO:0000209 33 0.025
regulation of protein catabolic process GO:0042176 108 0.025
skeletal muscle cell differentiation GO:0035914 66 0.025
calcium ion homeostasis GO:0055074 127 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.024
genitalia development GO:0048806 37 0.024
positive regulation of cell adhesion GO:0045785 80 0.024
regulation of membrane potential GO:0042391 192 0.024
Mouse
regulation of protein transport GO:0051223 163 0.024
regulation of canonical wnt signaling pathway GO:0060828 82 0.024
cellular divalent inorganic cation homeostasis GO:0072503 127 0.023
chemotaxis GO:0006935 247 0.023
negative regulation of immune system process GO:0002683 209 0.023
intracellular protein transport GO:0006886 204 0.023
heart trabecula morphogenesis GO:0061384 26 0.023
positive regulation of activin receptor signaling pathway GO:0032927 3 0.023
regulation of binding GO:0051098 111 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
negative regulation of wnt signaling pathway GO:0030178 73 0.023
single organism nuclear import GO:1902593 95 0.023
regulation of striated muscle contraction GO:0006942 25 0.023
nuclear import GO:0051170 95 0.023
cardiac muscle contraction GO:0060048 32 0.023
cellular response to hormone stimulus GO:0032870 150 0.022
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.022
multicellular organismal metabolic process GO:0044236 28 0.022
regulation of calcium ion dependent exocytosis GO:0017158 16 0.022
gtp catabolic process GO:0006184 143 0.022
nucleocytoplasmic transport GO:0006913 139 0.022
regulation of reproductive process GO:2000241 66 0.022
gland development GO:0048732 330 0.022
regulation of purine nucleotide catabolic process GO:0033121 122 0.022
response to decreased oxygen levels GO:0036293 59 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.022
endoderm development GO:0007492 45 0.022
regulation of microtubule cytoskeleton organization GO:0070507 37 0.022
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 6 0.022
cranial nerve morphogenesis GO:0021602 26 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
morphogenesis of a branching structure GO:0001763 203 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
muscle cell differentiation GO:0042692 261 0.021
glycerophospholipid metabolic process GO:0006650 71 0.021
renal system vasculature morphogenesis GO:0061438 7 0.021
microtubule cytoskeleton organization GO:0000226 157 0.021
cellular protein catabolic process GO:0044257 155 0.021
myeloid leukocyte differentiation GO:0002573 119 0.021
sequestering of metal ion GO:0051238 19 0.021
forelimb morphogenesis GO:0035136 40 0.021
floor plate formation GO:0021508 2 0.021
guanosine containing compound catabolic process GO:1901069 144 0.021
transition metal ion homeostasis GO:0055076 54 0.021
regulation of organ morphogenesis GO:2000027 144 0.021
cellular response to lipid GO:0071396 145 0.020
aromatic compound catabolic process GO:0019439 286 0.020
pharynx development GO:0060465 1 0.020
cellular response to peptide hormone stimulus GO:0071375 92 0.020
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.020
muscle contraction GO:0006936 101 0.020
single organism cell adhesion GO:0098602 156 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
cellular chemical homeostasis GO:0055082 215 0.020
embryonic camera type eye development GO:0031076 36 0.020
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
amine metabolic process GO:0009308 45 0.020
regulation of mitotic cell cycle phase transition GO:1901990 73 0.020
positive regulation of gene silencing by mirna GO:2000637 1 0.020
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.020
cellular homeostasis GO:0019725 240 0.019
placenta development GO:0001890 140 0.019
cation transport GO:0006812 399 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
inflammatory response GO:0006954 244 0.019
organic hydroxy compound biosynthetic process GO:1901617 77 0.019
regulation of ion transmembrane transport GO:0034765 119 0.019
cytokine production GO:0001816 319 0.019
potassium ion transport GO:0006813 52 0.019
negative regulation of neuron projection development GO:0010977 50 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
response to transforming growth factor beta GO:0071559 88 0.018
nephron tubule morphogenesis GO:0072078 68 0.018
regulation of cation channel activity GO:2001257 22 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
cytoplasmic transport GO:0016482 234 0.018
endocrine system development GO:0035270 98 0.018
mesoderm development GO:0007498 100 0.018
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.018
regulation of protein localization GO:0032880 231 0.018
negative regulation of cell development GO:0010721 169 0.017
regulation of cell cycle GO:0051726 281 0.017
cellular response to peptide GO:1901653 92 0.017
cellular calcium ion homeostasis GO:0006874 119 0.017
regulation of protein import into nucleus GO:0042306 52 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.017
regulation of monooxygenase activity GO:0032768 7 0.017
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.017
nodal signaling pathway GO:0038092 10 0.017
negative regulation of cell cycle process GO:0010948 69 0.017
mesenchymal cell differentiation GO:0048762 107 0.017
tongue muscle cell differentiation GO:0035981 2 0.017
negative regulation of transcription from rna polymerase ii promoter in response to stress GO:0097201 1 0.017
cellular response to acid chemical GO:0071229 68 0.017
nuclear transport GO:0051169 139 0.017
regulation of cell cycle phase transition GO:1901987 77 0.017
protein catabolic process GO:0030163 221 0.017
epithelial cilium movement GO:0003351 12 0.016
negative regulation of cell migration GO:0030336 59 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
cellular amide metabolic process GO:0043603 58 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
regulation of cellular response to insulin stimulus GO:1900076 30 0.016
kidney epithelium development GO:0072073 121 0.016
gtp metabolic process GO:0046039 144 0.016
response to peptide GO:1901652 136 0.016
digestive tract morphogenesis GO:0048546 147 0.016
Human
guanosine containing compound metabolic process GO:1901068 144 0.015
regulation of cell substrate adhesion GO:0010810 73 0.015
sodium ion transport GO:0006814 73 0.015
muscle tissue morphogenesis GO:0060415 53 0.015
response to growth factor GO:0070848 198 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
negative regulation of cell cycle phase transition GO:1901988 48 0.015
vacuole organization GO:0007033 38 0.015
nitric oxide metabolic process GO:0046209 25 0.015
regulation of cell motility GO:2000145 236 0.015
regulation of ion transport GO:0043269 215 0.015
cell cycle g1 s phase transition GO:0044843 57 0.015
response to ph GO:0009268 14 0.015
negative regulation of transcription factor import into nucleus GO:0042992 13 0.015
regulation of transcription factor import into nucleus GO:0042990 24 0.015
central nervous system neuron differentiation GO:0021953 162 0.015
cartilage development GO:0051216 140 0.015
placenta blood vessel development GO:0060674 31 0.015
hormone secretion GO:0046879 128 0.015
regulation of osteoblast differentiation GO:0045667 67 0.015
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.015
sensory perception of taste GO:0050909 18 0.015
response to organonitrogen compound GO:0010243 246 0.015
regulation of gtp catabolic process GO:0033124 113 0.015
organic cyclic compound catabolic process GO:1901361 295 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
glycerolipid metabolic process GO:0046486 122 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
negative regulation of homeostatic process GO:0032845 71 0.014
potassium ion transmembrane transport GO:0071805 43 0.014
organelle fission GO:0048285 170 0.014
renal artery morphogenesis GO:0061441 1 0.014
gene silencing by mirna GO:0035195 10 0.014
superoxide metabolic process GO:0006801 27 0.014
dna metabolic process GO:0006259 303 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.014
gene silencing by rna GO:0031047 19 0.014
organelle localization GO:0051640 179 0.014
regulation of anatomical structure size GO:0090066 178 0.014
odontogenesis of dentin containing tooth GO:0042475 66 0.014
somitogenesis GO:0001756 69 0.014
regulation of blood circulation GO:1903522 93 0.014
leukocyte differentiation GO:0002521 342 0.014
striated muscle hypertrophy GO:0014897 24 0.014
positive regulation of male gonad development GO:2000020 6 0.014
vagus nerve morphogenesis GO:0021644 2 0.014
smoothened signaling pathway involved in ventral spinal cord patterning GO:0021910 7 0.014
proximal tubule development GO:0072014 5 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
positive regulation of gtpase activity GO:0043547 85 0.014
regulation of multi organism process GO:0043900 111 0.014
regulation of cellular amino acid metabolic process GO:0006521 5 0.014
morphogenesis of a branching epithelium GO:0061138 193 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
adult behavior GO:0030534 135 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
transcription factor import into nucleus GO:0042991 26 0.013
cellular response to osmotic stress GO:0071470 7 0.013
maintenance of protein location in cell GO:0032507 20 0.013
nucleoside metabolic process GO:0009116 246 0.013
regulation of ras gtpase activity GO:0032318 88 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
adrenal cortex development GO:0035801 2 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
peptidyl amino acid modification GO:0018193 336 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
regulation of camp metabolic process GO:0030814 30 0.013
establishment or maintenance of cell polarity GO:0007163 86 0.013
positive regulation of protein localization to nucleus GO:1900182 30 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
nucleoside catabolic process GO:0009164 206 0.013
release of sequestered calcium ion into cytosol GO:0051209 42 0.013
negative regulation of protein transport GO:0051224 46 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.013
endomembrane system organization GO:0010256 147 0.013
ras protein signal transduction GO:0007265 77 0.013
regulation of metal ion transport GO:0010959 106 0.013
ventral midline development GO:0007418 4 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
trabecula morphogenesis GO:0061383 40 0.013
positive regulation of ion transmembrane transport GO:0034767 24 0.013
positive regulation of rab gtpase activity GO:0032851 7 0.013
skeletal muscle organ development GO:0060538 163 0.013
positive regulation of posttranscriptional gene silencing GO:0060148 1 0.013
specification of organ position GO:0010159 3 0.013
regulation of nucleocytoplasmic transport GO:0046822 73 0.013
penile erection GO:0043084 2 0.013
positive regulation of skeletal muscle cell differentiation GO:2001016 4 0.013
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 2 0.012
peptidyl serine phosphorylation GO:0018105 74 0.012
peripheral nervous system neuron axonogenesis GO:0048936 3 0.012
heterocycle catabolic process GO:0046700 280 0.012
hindbrain development GO:0030902 128 0.012
Mouse
regulation of hydrolase activity GO:0051336 246 0.012
loop of henle development GO:0072070 10 0.012
nephron epithelium development GO:0072009 92 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
specification of organ identity GO:0010092 30 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.012
response to inorganic substance GO:0010035 96 0.012
lymph vessel morphogenesis GO:0036303 11 0.012
cellular ion homeostasis GO:0006873 165 0.012
protein secretion GO:0009306 111 0.012
heart contraction GO:0060047 93 0.012
nephron development GO:0072006 109 0.012
regulation of oxidoreductase activity GO:0051341 15 0.012

Megf8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
primary ciliary dyskinesia DOID:9562 0 0.099
physical disorder DOID:0080015 0 0.079
disease of anatomical entity DOID:7 0 0.047
cardiovascular system disease DOID:1287 0 0.047
neuromuscular disease DOID:440 0 0.046
nervous system disease DOID:863 0 0.046
neuropathy DOID:870 0 0.046
heart disease DOID:114 0 0.028
charcot marie tooth disease DOID:10595 0 0.021
nephronophthisis DOID:12712 0 0.021