|
|
histone modification
|
GO:0016570 |
159 |
0.691
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.615
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.527
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.524
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.513
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.494
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.423
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.390
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.361
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.355
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.345
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.336
|
Human |
|
|
chromatin organization
|
GO:0006325 |
206 |
0.297
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.285
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.278
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.277
|
Human Fly |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.247
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.233
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.223
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.218
|
Human |
|
|
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072364 |
7 |
0.217
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.213
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.213
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.212
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.211
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.211
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.210
|
Human Fly |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.209
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.198
|
Fly |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.195
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.193
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.188
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.185
|
Human Fly |
|
|
nuclear division
|
GO:0000280 |
158 |
0.181
|
|
|
|
intra s dna damage checkpoint
|
GO:0031573 |
4 |
0.179
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.177
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.174
|
Fly |
|
|
histone methylation
|
GO:0016571 |
71 |
0.171
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.166
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.161
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.152
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.150
|
|
|
|
sterol metabolic process
|
GO:0016125 |
58 |
0.149
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.149
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.148
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.147
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.146
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.144
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.138
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.137
|
Fly |
|
|
histone h3 acetylation
|
GO:0043966 |
14 |
0.131
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.131
|
Fly |
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.130
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.130
|
|
|
|
protein dealkylation
|
GO:0008214 |
13 |
0.126
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.123
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.123
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.122
|
Fly |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.120
|
Fly |
|
|
demethylation
|
GO:0070988 |
23 |
0.120
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.115
|
Human |
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
9 |
0.114
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.114
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.114
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.113
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.112
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.112
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.111
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.108
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.107
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.106
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.105
|
|
|
|
hexose biosynthetic process
|
GO:0019319 |
39 |
0.103
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.103
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.103
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.102
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.101
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.101
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.101
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.100
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.099
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.096
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.096
|
Human |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.096
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.095
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.094
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.094
|
|
|
|
histone lysine demethylation
|
GO:0070076 |
13 |
0.093
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.093
|
|
|
|
histone demethylation
|
GO:0016577 |
13 |
0.091
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.091
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.090
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.090
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.089
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.089
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.088
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.088
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.088
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.088
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.087
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.087
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.087
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.086
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.086
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.084
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.083
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.082
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.082
|
|
|
|
chromatin silencing
|
GO:0006342 |
15 |
0.081
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.080
|
Human Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.080
|
Human |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.079
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.079
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.079
|
Human |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.078
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.078
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.077
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.077
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.075
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.075
|
|
|
|
negative regulation of fibroblast migration
|
GO:0010764 |
2 |
0.075
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.073
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.073
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.073
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.073
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.072
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.072
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.072
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.072
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.071
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.070
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.069
|
Human Fly |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.069
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.069
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.068
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.067
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.066
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.066
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.065
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
102 |
0.065
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.065
|
Human |
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.065
|
Fly |
|
|
histone deubiquitination
|
GO:0016578 |
2 |
0.065
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.064
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.064
|
|
|
|
attachment of spindle microtubules to kinetochore
|
GO:0008608 |
4 |
0.064
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.063
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.063
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.063
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.062
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.062
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.062
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.061
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.061
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.061
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.061
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.060
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.060
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.060
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.060
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
3 |
0.060
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.060
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.060
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.060
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.060
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.059
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.059
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.059
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.059
|
Human Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.059
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.059
|
Human |
|
|
organelle assembly
|
GO:0070925 |
177 |
0.059
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.058
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.058
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.058
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.058
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.058
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.056
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.056
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.056
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.056
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.056
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.055
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.055
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.055
|
Human |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.055
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.055
|
|
|
|
dna alkylation
|
GO:0006305 |
43 |
0.055
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.055
|
|
|
|
regulation of gluconeogenesis by regulation of transcription from rna polymerase ii promoter
|
GO:0035947 |
7 |
0.054
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.053
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.053
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.052
|
|
|
|
transdifferentiation
|
GO:0060290 |
1 |
0.052
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.052
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.051
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.051
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.050
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.050
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.050
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.050
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.050
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.049
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.049
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.049
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.049
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.049
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.049
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.049
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.049
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.048
|
Human |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.048
|
Human |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.048
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.048
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.047
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.047
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.047
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.047
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.047
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.047
|
|
|
|
retinal cone cell development
|
GO:0046549 |
8 |
0.047
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.046
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.046
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.045
|
Fly |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.045
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.045
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.045
|
|
|
|
triglyceride metabolic process
|
GO:0006641 |
51 |
0.044
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.044
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.044
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.044
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.043
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.043
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.043
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.042
|
Fly |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.042
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.042
|
|
|
|
histone h3 k4 methylation
|
GO:0051568 |
23 |
0.042
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.042
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.041
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.041
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.041
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.041
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.041
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.041
|
Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.040
|
|
|
|
sterol homeostasis
|
GO:0055092 |
45 |
0.040
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.040
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.040
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.040
|
|
|
|
protein deacetylation
|
GO:0006476 |
32 |
0.040
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.039
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.039
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.039
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.039
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.038
|
Human |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.038
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.038
|
Human Fly |
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.038
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.038
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
34 |
0.038
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.037
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.037
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.037
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
37 |
0.037
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
28 |
0.037
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.036
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.036
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.036
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.036
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.036
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.036
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.036
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.036
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.035
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.035
|
|
|
|
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway
|
GO:0043162 |
3 |
0.035
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.035
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.035
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.034
|
Human |
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.034
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.034
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.034
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.034
|
Fly |
|
|
histone h4 k16 acetylation
|
GO:0043984 |
3 |
0.034
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.034
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.034
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.033
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.033
|
|
|
|
regulation of mammary gland epithelial cell proliferation
|
GO:0033599 |
12 |
0.033
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.033
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.033
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.033
|
|
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.033
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.032
|
Human |
|
|
mitochondrial transport
|
GO:0006839 |
36 |
0.032
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.032
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
20 |
0.032
|
|
|
|
dna modification
|
GO:0006304 |
50 |
0.031
|
|
|
|
monosaccharide biosynthetic process
|
GO:0046364 |
44 |
0.031
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.031
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.031
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.031
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
3 |
0.031
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.031
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.030
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.030
|
|
|
|
positive regulation of gluconeogenesis by positive regulation of transcription from rna polymerase ii promoter
|
GO:0035948 |
5 |
0.030
|
|
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.030
|
|
|
|
cholesterol metabolic process
|
GO:0008203 |
56 |
0.030
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.030
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.029
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.029
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.029
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.029
|
|
|
|
somatic hypermutation of immunoglobulin genes
|
GO:0016446 |
7 |
0.029
|
|
|
|
histone h3 k9 acetylation
|
GO:0043970 |
5 |
0.029
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.029
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.029
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.029
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.028
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.028
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.028
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.028
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.028
|
Fly |
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.028
|
Fly |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.028
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.028
|
|
|
|
regulation of gluconeogenesis
|
GO:0006111 |
30 |
0.028
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.028
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.028
|
|
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.028
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.028
|
|
|
|
gluconeogenesis
|
GO:0006094 |
39 |
0.028
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.028
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
31 |
0.028
|
Fly |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.027
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.027
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.027
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.027
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.027
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.027
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.027
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.027
|
|
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
8 |
0.027
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.027
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.027
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.027
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.027
|
|
|
|
positive regulation of gluconeogenesis
|
GO:0045722 |
11 |
0.027
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.027
|
|
|
|
microtubule polymerization
|
GO:0046785 |
12 |
0.026
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.026
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.026
|
Human Fly |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.026
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.026
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.026
|
Human Fly |
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.026
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.026
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.026
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.026
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.026
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.026
|
|
|
|
somite development
|
GO:0061053 |
81 |
0.026
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
24 |
0.025
|
Fly |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.025
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.025
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.025
|
|
|
|
cellular response to nitric oxide
|
GO:0071732 |
4 |
0.025
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
1 |
0.025
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.025
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.025
|
|
|
|
retina homeostasis
|
GO:0001895 |
23 |
0.025
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.025
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.025
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.025
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.025
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
35 |
0.025
|
Fly |
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.025
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.025
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.024
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.024
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.024
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.024
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.024
|
|
|
|
cilium assembly
|
GO:0042384 |
81 |
0.024
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.024
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.024
|
|
|
|
protein localization to mitochondrion
|
GO:0070585 |
15 |
0.024
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.024
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.024
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.024
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.024
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.024
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.024
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
45 |
0.023
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.023
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.023
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.023
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.023
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.023
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.023
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.023
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.023
|
|
|
|
dna replication
|
GO:0006260 |
52 |
0.023
|
Human |
|
|
feeding behavior
|
GO:0007631 |
62 |
0.023
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.023
|
|
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.023
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.023
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.023
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.023
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.023
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.023
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.023
|
|
|
|
positive regulation of chromosome segregation
|
GO:0051984 |
4 |
0.022
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.022
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.022
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.022
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
80 |
0.022
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.022
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.022
|
Human |
|
|
macroautophagy
|
GO:0016236 |
21 |
0.022
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.022
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.022
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.022
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.022
|
|
|
|
protein demethylation
|
GO:0006482 |
13 |
0.022
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.022
|
Fly |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.022
|
Human |
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.022
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.021
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.021
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.021
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.021
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.021
|
|
|
|
detection of light stimulus
|
GO:0009583 |
25 |
0.021
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.021
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.021
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.021
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.021
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.021
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.021
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.021
|
Fly |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.021
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.021
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.021
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.021
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.021
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.020
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.020
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.020
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.020
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.020
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.020
|
|
|
|
positive regulation of mitotic sister chromatid separation
|
GO:1901970 |
2 |
0.020
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.020
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.020
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.020
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.020
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.020
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.020
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.020
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.020
|
|
|
|
fibroblast migration
|
GO:0010761 |
21 |
0.020
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.020
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.019
|
|
|
|
regulation of cholesterol metabolic process
|
GO:0090181 |
14 |
0.019
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.019
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.019
|
|
|
|
regulation of protein deacetylation
|
GO:0090311 |
17 |
0.019
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.019
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.019
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.019
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.019
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.019
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.019
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.019
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.019
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.019
|
|
|
|
negative regulation of dna recombination
|
GO:0045910 |
13 |
0.019
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.019
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.019
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.019
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
47 |
0.019
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.019
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.019
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.019
|
|
|
|
developmental pigmentation
|
GO:0048066 |
40 |
0.019
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.019
|
|
