Mus musculus

38 known processes

Mfn2

mitofusin 2

(Aliases: Fzo,D630023P19Rik)

Mfn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrial fusion GO:0008053 9 0.963
positive regulation of mitochondrion organization GO:0010822 17 0.894
Fly
response to endoplasmic reticulum stress GO:0034976 53 0.817
Fly
positive regulation of apoptotic signaling pathway GO:2001235 95 0.602
regulation of mitochondrial fission GO:0090140 3 0.523
Fly
regulation of mitochondrion organization GO:0010821 27 0.482
Fly
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.442
organelle fusion GO:0048284 28 0.432
mitochondrion organization GO:0007005 134 0.428
cellular lipid metabolic process GO:0044255 323 0.416
regulation of hydrolase activity GO:0051336 246 0.374
amine metabolic process GO:0009308 45 0.352
positive regulation of proteolysis GO:0045862 85 0.340
positive regulation of programmed cell death GO:0043068 218 0.323
release of cytochrome c from mitochondria GO:0001836 23 0.319
regulation of cellular catabolic process GO:0031329 242 0.313
positive regulation of apoptotic process GO:0043065 217 0.305
membrane fusion GO:0061025 38 0.304
apoptotic signaling pathway GO:0097190 306 0.303
cellular amine metabolic process GO:0044106 44 0.301
reactive oxygen species metabolic process GO:0072593 84 0.300
negative regulation of apoptotic signaling pathway GO:2001234 104 0.295
regulation of proteolysis GO:0030162 164 0.291
cation transport GO:0006812 399 0.285
regulation of peptidase activity GO:0052547 96 0.275
cation homeostasis GO:0055080 212 0.274
regulation of membrane potential GO:0042391 192 0.270
regulation of cellular amine metabolic process GO:0033238 20 0.250
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.237
activation of cysteine type endopeptidase activity GO:0097202 27 0.235
protein processing GO:0016485 163 0.234
positive regulation of organelle organization GO:0010638 128 0.231
Fly
regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway GO:1902235 11 0.227
regulation of cellular response to oxidative stress GO:1900407 19 0.215
regulation of apoptotic signaling pathway GO:2001233 197 0.212
positive regulation of cellular catabolic process GO:0031331 148 0.208
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.207
regulation of ion transport GO:0043269 215 0.203
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 3 0.198
response to organonitrogen compound GO:0010243 246 0.195
anatomical structure homeostasis GO:0060249 145 0.193
positive regulation of cell death GO:0010942 224 0.190
urogenital system development GO:0001655 261 0.189
nucleobase containing small molecule metabolic process GO:0055086 352 0.188
positive regulation of endopeptidase activity GO:0010950 43 0.186
monoamine transport GO:0015844 33 0.183
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.181
regulation of cellular ketone metabolic process GO:0010565 66 0.181
regulation of nucleoside metabolic process GO:0009118 130 0.174
camera type eye development GO:0043010 266 0.172
negative regulation of phosphorylation GO:0042326 166 0.170
nucleoside phosphate metabolic process GO:0006753 338 0.168
peptidyl serine phosphorylation GO:0018105 74 0.167
negative regulation of cellular amine metabolic process GO:0033239 1 0.166
regulation of engulfment of apoptotic cell GO:1901074 2 0.163
protein maturation GO:0051604 176 0.160
organic hydroxy compound metabolic process GO:1901615 203 0.159
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.153
sequestering of metal ion GO:0051238 19 0.153
homeostasis of number of cells GO:0048872 210 0.152
response to oxidative stress GO:0006979 123 0.151
protein localization to organelle GO:0033365 185 0.150
purine ribonucleoside metabolic process GO:0046128 241 0.147
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.145
organonitrogen compound catabolic process GO:1901565 264 0.144
regulation of cysteine type endopeptidase activity GO:2000116 65 0.144
cellular ion homeostasis GO:0006873 165 0.144
cellular ketone metabolic process GO:0042180 84 0.144
negative regulation of growth GO:0045926 99 0.143
divalent inorganic cation transport GO:0072511 178 0.142
purine ribonucleotide metabolic process GO:0009150 290 0.141
regulation of cellular amino acid metabolic process GO:0006521 5 0.141
cellular response to oxidative stress GO:0034599 76 0.140
regulation of endopeptidase activity GO:0052548 89 0.138
positive regulation of cellular amine metabolic process GO:0033240 5 0.137
neuron apoptotic process GO:0051402 142 0.137
sequestering of calcium ion GO:0051208 18 0.135
regulation of neuron death GO:1901214 134 0.133
regulation of organelle organization GO:0033043 289 0.132
Fly
cellular homeostasis GO:0019725 240 0.132
regulation of cellular response to stress GO:0080135 159 0.131
positive regulation of peptidase activity GO:0010952 49 0.129
positive regulation of mitochondrial fission GO:0090141 2 0.129
regulation of ion homeostasis GO:2000021 64 0.126
negative regulation of protein phosphorylation GO:0001933 126 0.126
apoptotic mitochondrial changes GO:0008637 48 0.124
cellular calcium ion homeostasis GO:0006874 119 0.124
negative regulation of phagocytosis GO:0050765 4 0.122
cellular metal ion homeostasis GO:0006875 151 0.122
release of sequestered calcium ion into cytosol GO:0051209 42 0.121
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.118
protein modification by small protein conjugation or removal GO:0070647 207 0.118
male gamete generation GO:0048232 285 0.117
regulation of cell migration GO:0030334 219 0.117
cell type specific apoptotic process GO:0097285 268 0.116
membrane organization GO:0061024 245 0.114
negative regulation of cellular protein metabolic process GO:0032269 247 0.113
regulation of response to oxidative stress GO:1902882 19 0.112
negative regulation of neuron apoptotic process GO:0043524 92 0.111
cellular amino acid metabolic process GO:0006520 103 0.111
response to oxygen levels GO:0070482 62 0.110
actin filament organization GO:0007015 113 0.109
cytosolic calcium ion transport GO:0060401 48 0.109
regulation of cell growth GO:0001558 91 0.106
purine nucleoside metabolic process GO:0042278 241 0.106
developmental maturation GO:0021700 193 0.106
cellular response to gamma radiation GO:0071480 4 0.106
regulation of calcium ion transport GO:0051924 69 0.106
nucleoside metabolic process GO:0009116 246 0.105
actin cytoskeleton organization GO:0030036 220 0.105
metencephalon development GO:0022037 89 0.105
maintenance of location GO:0051235 89 0.105
regulation of metal ion transport GO:0010959 106 0.104
fatty acid metabolic process GO:0006631 121 0.104
germ cell development GO:0007281 185 0.103
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.101
divalent metal ion transport GO:0070838 172 0.101
response to extracellular stimulus GO:0009991 127 0.099
negative regulation of phosphorus metabolic process GO:0010563 184 0.098
calcium ion transport into cytosol GO:0060402 48 0.097
positive regulation of hydrolase activity GO:0051345 148 0.097
regulation of neurotransmitter levels GO:0001505 87 0.097
regulation of neuron apoptotic process GO:0043523 122 0.097
positive regulation of binding GO:0051099 49 0.096
metal ion homeostasis GO:0055065 189 0.096
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 2 0.095
response to organic cyclic compound GO:0014070 198 0.095
nucleotide catabolic process GO:0009166 217 0.092
positive regulation of protein modification process GO:0031401 299 0.092
cytoplasmic transport GO:0016482 234 0.090
purine containing compound catabolic process GO:0072523 213 0.090
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 11 0.090
regulation of cytoplasmic transport GO:1903649 112 0.089
purine containing compound metabolic process GO:0072521 311 0.089
autophagy GO:0006914 45 0.089
regulation of nucleotide metabolic process GO:0006140 169 0.089
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.088
lymphocyte differentiation GO:0030098 242 0.087
spermatogenesis GO:0007283 284 0.087
positive regulation of smooth muscle cell migration GO:0014911 4 0.086
kidney development GO:0001822 213 0.086
axonogenesis GO:0007409 274 0.086
t cell activation GO:0042110 289 0.086
peptidyl amino acid modification GO:0018193 336 0.086
positive regulation of homeostatic process GO:0032846 64 0.085
response to reactive oxygen species GO:0000302 56 0.084
muscle tissue development GO:0060537 308 0.084
cellular response to acid chemical GO:0071229 68 0.083
negative regulation of phosphate metabolic process GO:0045936 184 0.083
dopamine metabolic process GO:0042417 23 0.083
protein ubiquitination GO:0016567 171 0.083
ribonucleoside triphosphate catabolic process GO:0009203 199 0.082
phenol containing compound metabolic process GO:0018958 60 0.082
purine nucleotide metabolic process GO:0006163 302 0.082
cellular chemical homeostasis GO:0055082 215 0.082
peptidyl serine modification GO:0018209 83 0.081
ribose phosphate metabolic process GO:0019693 291 0.081
cellular response to cytokine stimulus GO:0071345 189 0.080
aromatic compound catabolic process GO:0019439 286 0.080
engulfment of apoptotic cell GO:0043652 3 0.079
positive regulation of ion transport GO:0043270 65 0.079
t cell differentiation GO:0030217 174 0.079
ossification GO:0001503 216 0.079
positive regulation of intracellular transport GO:0032388 70 0.079
regulation of intracellular transport GO:0032386 159 0.078
renal system development GO:0072001 225 0.078
synaptic transmission GO:0007268 329 0.078
negative regulation of cell proliferation GO:0008285 296 0.077
negative regulation of cell growth GO:0030308 44 0.077
ribonucleotide catabolic process GO:0009261 208 0.076
multicellular organismal homeostasis GO:0048871 164 0.076
ribonucleotide metabolic process GO:0009259 291 0.076
response to acid chemical GO:0001101 111 0.076
regulation of cell cycle process GO:0010564 160 0.076
regulation of protein localization GO:0032880 231 0.076
protein localization to mitochondrion GO:0070585 15 0.075
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.075
hematopoietic progenitor cell differentiation GO:0002244 143 0.075
ovarian follicle development GO:0001541 40 0.074
ribonucleoside catabolic process GO:0042454 206 0.074
protein modification by small protein conjugation GO:0032446 187 0.074
regulation of purine nucleotide catabolic process GO:0033121 122 0.074
glycosyl compound catabolic process GO:1901658 206 0.073
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903378 3 0.073
striated muscle tissue development GO:0014706 293 0.073
catecholamine transport GO:0051937 21 0.073
female gamete generation GO:0007292 74 0.072
blood vessel morphogenesis GO:0048514 285 0.072
zymogen activation GO:0031638 41 0.072
myotube cell development GO:0014904 60 0.072
positive regulation of response to oxidative stress GO:1902884 6 0.071
limb development GO:0060173 166 0.071
cd8 positive alpha beta t cell lineage commitment GO:0043375 1 0.071
regulation of homeostatic process GO:0032844 182 0.071
regulation of hormone levels GO:0010817 211 0.070
cellular nitrogen compound catabolic process GO:0044270 280 0.069
positive regulation of cellular response to oxidative stress GO:1900409 6 0.069
negative regulation of ossification GO:0030279 49 0.069
oogenesis GO:0048477 56 0.069
negative regulation of intracellular signal transduction GO:1902532 167 0.069
oxidation reduction process GO:0055114 342 0.069
catecholamine metabolic process GO:0006584 30 0.069
regulation of calcium ion transport into cytosol GO:0010522 31 0.068
mitochondrion degradation GO:0000422 3 0.068
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.068
neuron death GO:0070997 154 0.068
regulation of reactive oxygen species metabolic process GO:2000377 40 0.067
myeloid cell homeostasis GO:0002262 114 0.067
response to radiation GO:0009314 165 0.067
organic cyclic compound catabolic process GO:1901361 295 0.066
purine ribonucleotide catabolic process GO:0009154 208 0.066
dephosphorylation GO:0016311 129 0.066
molting cycle GO:0042303 90 0.066
spermatid differentiation GO:0048515 115 0.066
posttranscriptional regulation of gene expression GO:0010608 155 0.065
cellular response to dna damage stimulus GO:0006974 207 0.065
locomotory behavior GO:0007626 195 0.065
Fly
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 11 0.064
negative regulation of cell motility GO:2000146 61 0.063
mitochondrial membrane organization GO:0007006 26 0.063
positive regulation of neuron apoptotic process GO:0043525 25 0.063
stem cell development GO:0048864 219 0.063
organonitrogen compound biosynthetic process GO:1901566 192 0.062
ear development GO:0043583 200 0.062
cytosolic calcium ion homeostasis GO:0051480 70 0.062
skeletal muscle fiber development GO:0048741 58 0.062
neurotransmitter uptake GO:0001504 14 0.062
regulation of peptidyl serine phosphorylation GO:0033135 39 0.061
positive regulation of cell migration GO:0030335 109 0.061
leukocyte differentiation GO:0002521 342 0.061
hindbrain development GO:0030902 128 0.061
establishment of protein localization to organelle GO:0072594 118 0.060
modification dependent macromolecule catabolic process GO:0043632 133 0.060
response to hypoxia GO:0001666 58 0.060
regulation of kinase activity GO:0043549 249 0.060
sensory organ morphogenesis GO:0090596 242 0.059
purine nucleoside catabolic process GO:0006152 205 0.059
digestive tract development GO:0048565 190 0.058
retina development in camera type eye GO:0060041 119 0.058
response to steroid hormone GO:0048545 56 0.057
neuromuscular process GO:0050905 99 0.057
negative regulation of molecular function GO:0044092 258 0.057
response to amino acid GO:0043200 37 0.057
fat cell differentiation GO:0045444 160 0.057
regulation of neuron differentiation GO:0045664 281 0.057
skin development GO:0043588 220 0.057
cell growth GO:0016049 130 0.057
stem cell differentiation GO:0048863 268 0.057
carbohydrate derivative biosynthetic process GO:1901137 183 0.057
negative regulation of cell migration GO:0030336 59 0.057
skeletal muscle organ development GO:0060538 163 0.056
cellular divalent inorganic cation homeostasis GO:0072503 127 0.056
negative regulation of neuron death GO:1901215 98 0.056
protein insertion into mitochondrial membrane GO:0051204 4 0.056
purine nucleoside triphosphate catabolic process GO:0009146 203 0.056
muscle fiber development GO:0048747 76 0.056
response to inorganic substance GO:0010035 96 0.055
protein oligomerization GO:0051259 67 0.055
regulation of cell motility GO:2000145 236 0.055
organelle fission GO:0048285 170 0.055
Fly
purine ribonucleoside catabolic process GO:0046130 205 0.055
cation transmembrane transport GO:0098655 266 0.054
regulation of transferase activity GO:0051338 263 0.054
regulation of vesicle mediated transport GO:0060627 139 0.054
regulation of ossification GO:0030278 112 0.054
regulation of cell adhesion GO:0030155 154 0.053
heterocycle catabolic process GO:0046700 280 0.053
neuron intrinsic apoptotic signaling pathway in response to oxidative stress GO:0036480 3 0.053
intrinsic apoptotic signaling pathway GO:0097193 132 0.053
response to nutrient levels GO:0031667 109 0.053
regulation of epithelial cell proliferation GO:0050678 141 0.052
regulation of cell cycle GO:0051726 281 0.052
negative regulation of calcium ion transport GO:0051926 9 0.052
regulation of protein stability GO:0031647 52 0.052
regulation of mitotic cell cycle phase transition GO:1901990 73 0.051
cell fate commitment GO:0045165 210 0.051
cell adhesion GO:0007155 329 0.051
nucleoside triphosphate catabolic process GO:0009143 205 0.051
regulation of cellular component biogenesis GO:0044087 181 0.051
response to drug GO:0042493 75 0.051
peptide secretion GO:0002790 114 0.051
positive regulation of protein phosphorylation GO:0001934 242 0.050
lymphocyte homeostasis GO:0002260 64 0.050
regulation of system process GO:0044057 200 0.049
modification dependent protein catabolic process GO:0019941 133 0.049
neurotransmitter transport GO:0006836 76 0.049
epithelial cell proliferation GO:0050673 174 0.049
signal transduction in absence of ligand GO:0038034 55 0.049
nucleoside triphosphate metabolic process GO:0009141 230 0.049
single organismal cell cell adhesion GO:0016337 131 0.049
guanosine containing compound metabolic process GO:1901068 144 0.048
cellular response to amino acid stimulus GO:0071230 29 0.048
regulation of release of cytochrome c from mitochondria GO:0090199 11 0.048
response to uv GO:0009411 44 0.048
positive regulation of nucleotide metabolic process GO:0045981 114 0.048
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.048
peptide transport GO:0015833 133 0.048
dopamine transport GO:0015872 15 0.047
cell substrate adhesion GO:0031589 130 0.047
cellular response to nutrient levels GO:0031669 64 0.047
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.047
telencephalon development GO:0021537 186 0.047
lipid biosynthetic process GO:0008610 179 0.047
regulation of muscle system process GO:0090257 80 0.047
muscle cell differentiation GO:0042692 261 0.047
dopamine catabolic process GO:0042420 4 0.047
protein homooligomerization GO:0051260 43 0.047
t cell proliferation GO:0042098 120 0.046
forebrain development GO:0030900 302 0.046
negative regulation of cell development GO:0010721 169 0.046
b cell proliferation GO:0042100 53 0.046
mitotic cell cycle GO:0000278 195 0.046
organic hydroxy compound transport GO:0015850 93 0.046
response to peptide GO:1901652 136 0.046
membrane lipid metabolic process GO:0006643 53 0.046
ubiquitin dependent protein catabolic process GO:0006511 129 0.045
regulation of binding GO:0051098 111 0.045
positive regulation of nervous system development GO:0051962 221 0.045
renal tubule development GO:0061326 87 0.045
regulation of cell cycle phase transition GO:1901987 77 0.045
response to iron ion GO:0010039 4 0.045
gtp catabolic process GO:0006184 143 0.045
transmission of nerve impulse GO:0019226 76 0.044
nitrogen compound transport GO:0071705 271 0.044
sphingolipid metabolic process GO:0006665 45 0.044
epithelial tube morphogenesis GO:0060562 303 0.044
mitochondrion morphogenesis GO:0070584 13 0.044
Fly
positive regulation of cell motility GO:2000147 116 0.044
tissue homeostasis GO:0001894 115 0.043
blood circulation GO:0008015 195 0.043
guanosine containing compound catabolic process GO:1901069 144 0.043
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 9 0.043
epidermis development GO:0008544 187 0.043
macromolecule catabolic process GO:0009057 281 0.043
mitotic cell cycle process GO:1903047 159 0.042
nucleoside catabolic process GO:0009164 206 0.042
negative regulation of osteoblast proliferation GO:0033689 4 0.042
positive regulation of growth GO:0045927 104 0.042
Worm
stress activated protein kinase signaling cascade GO:0031098 81 0.042
gland development GO:0048732 330 0.042
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.042
cytokine mediated signaling pathway GO:0019221 115 0.042
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.042
regulation of purine nucleotide metabolic process GO:1900542 169 0.042
peptide hormone secretion GO:0030072 109 0.041
negative regulation of homeostatic process GO:0032845 71 0.041
signal transduction by p53 class mediator GO:0072331 51 0.041
negative regulation of cellular component organization GO:0051129 194 0.041
positive regulation of nucleotide catabolic process GO:0030813 88 0.041
response to ischemia GO:0002931 14 0.041
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001267 4 0.040
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.040
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c GO:0008635 4 0.040
regulation of action potential GO:0098900 4 0.040
purine nucleotide catabolic process GO:0006195 211 0.040
necrotic cell death GO:0070265 30 0.040
regulation of neurotransmitter transport GO:0051588 35 0.040
regulation of striated muscle cell differentiation GO:0051153 81 0.039
amide transport GO:0042886 138 0.039
regulation of myotube differentiation GO:0010830 62 0.039
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.039
circulatory system process GO:0003013 197 0.039
cellular response to organonitrogen compound GO:0071417 145 0.039
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.039
leukocyte homeostasis GO:0001776 79 0.039
limb morphogenesis GO:0035108 149 0.039
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:0001844 4 0.039
serotonin uptake GO:0051610 3 0.038
translation GO:0006412 93 0.038
ovulation cycle GO:0042698 59 0.038
positive regulation of nucleoside metabolic process GO:0045979 91 0.038
positive regulation of gtpase activity GO:0043547 85 0.038
positive regulation of gtp catabolic process GO:0033126 85 0.038
leukocyte proliferation GO:0070661 172 0.038
regulation of mitotic cell cycle GO:0007346 126 0.038
cerebral cortex development GO:0021987 86 0.038
angiogenesis GO:0001525 201 0.038
regulation of gtp catabolic process GO:0033124 113 0.038
single organism cell adhesion GO:0098602 156 0.037
protein catabolic process GO:0030163 221 0.037
response to starvation GO:0042594 65 0.037
regulation of actin filament based process GO:0032970 99 0.037
myotube differentiation GO:0014902 105 0.037
glycosyl compound metabolic process GO:1901657 246 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.037
t cell differentiation in thymus GO:0033077 77 0.037
regulation of autophagy GO:0010506 30 0.037
kidney epithelium development GO:0072073 121 0.037
regulation of multi organism process GO:0043900 111 0.036
cell cycle g1 s phase transition GO:0044843 57 0.036
establishment of protein localization to membrane GO:0090150 54 0.036
nucleotide metabolic process GO:0009117 332 0.036
regulation of cell substrate adhesion GO:0010810 73 0.036
regulation of protein kinase activity GO:0045859 232 0.036
monocarboxylic acid metabolic process GO:0032787 191 0.036
ribonucleoside metabolic process GO:0009119 245 0.036
diencephalon development GO:0021536 63 0.036
striated muscle cell development GO:0055002 125 0.036
heart process GO:0003015 94 0.035
regulation of protein binding GO:0043393 60 0.035
organelle assembly GO:0070925 177 0.035
calcium ion transport GO:0006816 159 0.035
pigmentation GO:0043473 71 0.035
second messenger mediated signaling GO:0019932 73 0.035
hormone secretion GO:0046879 128 0.035
protein polyubiquitination GO:0000209 33 0.035
appendage morphogenesis GO:0035107 149 0.035
pigment cell differentiation GO:0050931 27 0.035
appendage development GO:0048736 166 0.035
l amino acid transport GO:0015807 32 0.035
inclusion body assembly GO:0070841 3 0.034
cellular response to external stimulus GO:0071496 88 0.034
cellular component assembly involved in morphogenesis GO:0010927 139 0.034
cellular protein catabolic process GO:0044257 155 0.034
norepinephrine secretion GO:0048243 2 0.034
neural nucleus development GO:0048857 22 0.034
organophosphate catabolic process GO:0046434 232 0.034
g1 s transition of mitotic cell cycle GO:0000082 57 0.034
b cell activation GO:0042113 161 0.034
regulation of protein catabolic process GO:0042176 108 0.034
glycoprotein biosynthetic process GO:0009101 89 0.034
nucleoside phosphate catabolic process GO:1901292 222 0.033
response to ionizing radiation GO:0010212 42 0.033
norepinephrine transport GO:0015874 2 0.033
heart morphogenesis GO:0003007 178 0.033
extrinsic apoptotic signaling pathway GO:0097191 126 0.033
gtp metabolic process GO:0046039 144 0.033
monosaccharide metabolic process GO:0005996 106 0.033
lymphocyte proliferation GO:0046651 164 0.033
regulation of lymphocyte apoptotic process GO:0070228 41 0.033
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.033
myeloid cell differentiation GO:0030099 233 0.033
connective tissue development GO:0061448 179 0.032
cell junction organization GO:0034330 77 0.032
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.032
multi multicellular organism process GO:0044706 109 0.032
dopamine uptake involved in synaptic transmission GO:0051583 4 0.032
positive regulation of neuron differentiation GO:0045666 141 0.032
muscle cell development GO:0055001 133 0.032
regulation of protein transport GO:0051223 163 0.032
cell aging GO:0007569 35 0.032
homeostasis of number of cells within a tissue GO:0048873 25 0.032
endomembrane system organization GO:0010256 147 0.032
Fly
inorganic ion transmembrane transport GO:0098660 234 0.032
cellular response to biotic stimulus GO:0071216 92 0.032
mitochondrial transport GO:0006839 36 0.032
regulation of mitochondrial membrane potential GO:0051881 17 0.032
inorganic cation transmembrane transport GO:0098662 207 0.032
organophosphate biosynthetic process GO:0090407 122 0.032
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.032
multicellular organismal signaling GO:0035637 91 0.032
negative regulation of ion transport GO:0043271 28 0.032
amino acid transmembrane transport GO:0003333 37 0.031
male sex differentiation GO:0046661 109 0.031
negative regulation of cellular response to oxidative stress GO:1900408 10 0.031
muscle contraction GO:0006936 101 0.031
atp metabolic process GO:0046034 75 0.031
action potential GO:0001508 78 0.031
cochlear nucleus development GO:0021747 4 0.031
blood vessel remodeling GO:0001974 33 0.031
neurotransmitter secretion GO:0007269 62 0.031
cell death in response to oxidative stress GO:0036473 24 0.031
regulation of organ morphogenesis GO:2000027 144 0.030
neuron migration GO:0001764 122 0.030
cellular response to radiation GO:0071478 28 0.030
amino acid transport GO:0006865 61 0.030
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.030
negative regulation of cell cycle process GO:0010948 69 0.030
positive regulation of mammary gland involution GO:1903521 4 0.030
b cell homeostasis GO:0001782 34 0.030
positive regulation of apoptotic process involved in morphogenesis GO:1902339 4 0.030
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 3 0.030
nephron tubule development GO:0072080 84 0.030
cellular response to light stimulus GO:0071482 19 0.029
cellular response to starvation GO:0009267 57 0.029
response to light stimulus GO:0009416 135 0.029
apoptotic process involved in mammary gland involution GO:0060057 4 0.029
skeletal system development GO:0001501 356 0.029
learning or memory GO:0007611 148 0.029
chemotaxis GO:0006935 247 0.029
learning GO:0007612 98 0.029
dopamine uptake GO:0090494 4 0.029
regulation of mammary gland involution GO:1903519 4 0.028
cilium morphogenesis GO:0060271 102 0.028
digestive tract morphogenesis GO:0048546 147 0.028
regulation of secretion by cell GO:1903530 249 0.028
response to lipopolysaccharide GO:0032496 128 0.028

Mfn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.153
nervous system disease DOID:863 0 0.153
central nervous system disease DOID:331 0 0.117
cancer DOID:162 0 0.109
disease of cellular proliferation DOID:14566 0 0.109
organ system cancer DOID:0050686 0 0.063
neurodegenerative disease DOID:1289 0 0.047
muscular disease DOID:0080000 0 0.035
musculoskeletal system disease DOID:17 0 0.035
muscle tissue disease DOID:66 0 0.035