Mus musculus

102 known processes

Mkl2

MKL/myocardin-like 2

(Aliases: KIAA1243,mKIAA1243,Gt4-1,MRTF-B,Mrtfb,MGC41582,ENSMUSG00000075401)

Mkl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 243 0.670
negative regulation of apoptotic signaling pathway GO:2001234 104 0.324
Mouse
vegf activated neuropilin signaling pathway GO:0038190 2 0.281
protein localization to endosome GO:0036010 2 0.279
amine metabolic process GO:0009308 45 0.267
erk1 and erk2 cascade GO:0070371 77 0.262
protein processing GO:0016485 163 0.257
Mouse
nucleotide metabolic process GO:0009117 332 0.241
muscle system process GO:0003012 141 0.233
neuropilin signaling pathway GO:0038189 2 0.223
purine nucleotide metabolic process GO:0006163 302 0.216
regulation of cellular ketone metabolic process GO:0010565 66 0.215
vegf activated neuropilin signaling pathway involved in axon guidance GO:1902378 1 0.210
regulation of cellular response to stress GO:0080135 159 0.207
purine ribonucleotide metabolic process GO:0009150 290 0.202
ribose phosphate metabolic process GO:0019693 291 0.201
regulation of nucleotide metabolic process GO:0006140 169 0.183
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.181
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.178
muscle adaptation GO:0043500 39 0.175
peptidyl amino acid modification GO:0018193 336 0.171
Mouse
positive regulation of nucleotide metabolic process GO:0045981 114 0.171
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.163
purine containing compound metabolic process GO:0072521 311 0.159
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.157
branchiomotor neuron axon guidance GO:0021785 7 0.155
positive regulation of cellular amine metabolic process GO:0033240 5 0.152
regulation of peptidase activity GO:0052547 96 0.150
Mouse
rhodopsin mediated signaling pathway GO:0016056 4 0.148
cellular amino acid metabolic process GO:0006520 103 0.145
positive regulation of protein phosphorylation GO:0001934 242 0.137
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.137
cell type specific apoptotic process GO:0097285 268 0.136
Mouse
cellular amine metabolic process GO:0044106 44 0.135
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.134
organophosphate biosynthetic process GO:0090407 122 0.133
response to sterol GO:0036314 4 0.128
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.128
cation transport GO:0006812 399 0.126
regulation of erk1 and erk2 cascade GO:0070372 71 0.124
regulation of camp biosynthetic process GO:0030817 25 0.124
regulation of mapk cascade GO:0043408 248 0.123
regulation of anatomical structure size GO:0090066 178 0.121
nucleobase containing small molecule metabolic process GO:0055086 352 0.121
trunk neural crest cell migration GO:0036484 4 0.121
anatomical structure arrangement GO:0048532 20 0.120
regulation of ion transport GO:0043269 215 0.118
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.117
mapk cascade GO:0000165 281 0.116
cerebellar granule cell precursor tangential migration GO:0021935 1 0.114
growth plate cartilage chondrocyte growth GO:0003430 2 0.114
blood circulation GO:0008015 195 0.111
small gtpase mediated signal transduction GO:0007264 97 0.109
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.107
ribose phosphate biosynthetic process GO:0046390 59 0.099
ras protein signal transduction GO:0007265 77 0.099
sequestering of calcium ion GO:0051208 18 0.098
p38mapk cascade GO:0038066 4 0.097
regulation of blood pressure GO:0008217 93 0.096
nucleoside triphosphate metabolic process GO:0009141 230 0.096
purine nucleoside triphosphate catabolic process GO:0009146 203 0.095
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.094
growth plate cartilage chondrocyte development GO:0003431 3 0.094
apoptotic signaling pathway GO:0097190 306 0.092
Mouse
regulation of secretion GO:0051046 274 0.092
organophosphate catabolic process GO:0046434 232 0.089
muscle contraction GO:0006936 101 0.088
blood vessel morphogenesis GO:0048514 285 0.088
nucleoside phosphate metabolic process GO:0006753 338 0.087
regulation of cellular amine metabolic process GO:0033238 20 0.086
cellular ketone metabolic process GO:0042180 84 0.084
cellular nitrogen compound catabolic process GO:0044270 280 0.084
heart morphogenesis GO:0003007 178 0.084
positive regulation of cellular component biogenesis GO:0044089 94 0.084
actin cytoskeleton organization GO:0030036 220 0.083
Fly
response to organonitrogen compound GO:0010243 246 0.081
cardiocyte differentiation GO:0035051 87 0.081
Mouse
hypothalamic tangential migration using cell axon interactions GO:0021856 3 0.081
response to decreased oxygen levels GO:0036293 59 0.081
Fly
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.081
organic cyclic compound catabolic process GO:1901361 295 0.080
leukocyte differentiation GO:0002521 342 0.079
maintenance of location GO:0051235 89 0.078
striated muscle tissue development GO:0014706 293 0.078
positive regulation of retinal ganglion cell axon guidance GO:1902336 2 0.078
regulation of cellular component size GO:0032535 121 0.078
nucleotide catabolic process GO:0009166 217 0.077
epithelial cell proliferation GO:0050673 174 0.077
positive regulation of axon extension GO:0045773 20 0.077
positive regulation of protein modification process GO:0031401 299 0.076
multicellular organism growth GO:0035264 161 0.076
renal system development GO:0072001 225 0.075
Mouse
neuron apoptotic process GO:0051402 142 0.075
myotube differentiation GO:0014902 105 0.072
Mouse
adaptation of rhodopsin mediated signaling GO:0016062 2 0.071
regulation of muscle system process GO:0090257 80 0.071
angiogenesis GO:0001525 201 0.071
cation transmembrane transport GO:0098655 266 0.070
nitrogen compound transport GO:0071705 271 0.070
nucleotide biosynthetic process GO:0009165 78 0.070
membrane organization GO:0061024 245 0.070
regulation of vesicle mediated transport GO:0060627 139 0.069
cellular response to growth factor stimulus GO:0071363 197 0.069
Mouse
regulation of cell migration GO:0030334 219 0.068
regulation of retinal ganglion cell axon guidance GO:0090259 2 0.068
carbohydrate derivative biosynthetic process GO:1901137 183 0.068
aromatic compound catabolic process GO:0019439 286 0.068
sequestering of metal ion GO:0051238 19 0.067
regulation of purine nucleotide metabolic process GO:1900542 169 0.067
regulation of cellular amino acid metabolic process GO:0006521 5 0.067
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.066
ribonucleotide metabolic process GO:0009259 291 0.066
negative regulation of phosphorylation GO:0042326 166 0.066
purine ribonucleotide biosynthetic process GO:0009152 59 0.066
hepatocyte growth factor receptor signaling pathway GO:0048012 3 0.065
embryonic organ morphogenesis GO:0048562 276 0.064
fused antrum stage GO:0048165 1 0.064
response to muscle stretch GO:0035994 1 0.062
regulation of reactive oxygen species metabolic process GO:2000377 40 0.062
cellular response to organic cyclic compound GO:0071407 87 0.062
ventral trunk neural crest cell migration GO:0036486 4 0.062
developmental growth involved in morphogenesis GO:0060560 138 0.061
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.061
cyclic nucleotide biosynthetic process GO:0009190 44 0.060
regulation of defense response GO:0031347 233 0.060
ribonucleoside metabolic process GO:0009119 245 0.060
hindbrain development GO:0030902 128 0.060
response to oxygen levels GO:0070482 62 0.060
Fly
positive regulation of mapk cascade GO:0043410 170 0.060
muscle tissue development GO:0060537 308 0.059
sensory perception GO:0007600 245 0.058
purine ribonucleoside catabolic process GO:0046130 205 0.058
cytoplasmic transport GO:0016482 234 0.058
positive regulation of nervous system development GO:0051962 221 0.057
regulation of b cell tolerance induction GO:0002661 2 0.057
ameboidal type cell migration GO:0001667 128 0.057
Fly
metal ion homeostasis GO:0055065 189 0.057
circulatory system process GO:0003013 197 0.056
cellular response to hepatocyte growth factor stimulus GO:0035729 2 0.056
regulation of blood circulation GO:1903522 93 0.056
cartilage development GO:0051216 140 0.056
purine nucleotide catabolic process GO:0006195 211 0.056
t cell differentiation GO:0030217 174 0.055
protein localization to organelle GO:0033365 185 0.055
neural crest cell development GO:0014032 48 0.055
neural crest cell differentiation GO:0014033 54 0.055
regulation of cell activation GO:0050865 289 0.055
regulation of blood vessel size GO:0050880 56 0.054
protein localization to early endosome GO:1902946 1 0.054
nucleoside metabolic process GO:0009116 246 0.054
urogenital system development GO:0001655 261 0.053
Mouse
gtp catabolic process GO:0006184 143 0.052
trachea formation GO:0060440 3 0.052
ribonucleotide biosynthetic process GO:0009260 59 0.052
mullerian duct regression GO:0001880 1 0.052
regulation of organelle organization GO:0033043 289 0.052
Mouse
histone modification GO:0016570 159 0.051
Mouse
cellular response to oxidative stress GO:0034599 76 0.050
nucleoside catabolic process GO:0009164 206 0.050
receptor recycling GO:0001881 11 0.050
regulation of tube size GO:0035150 57 0.050
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.050
positive regulation of gtp catabolic process GO:0033126 85 0.050
inflammatory response GO:0006954 244 0.049
positive regulation of cellular catabolic process GO:0031331 148 0.049
hypothalamus gonadotrophin releasing hormone neuron differentiation GO:0021886 4 0.049
positive regulation of odontogenesis GO:0042482 4 0.049
carbohydrate derivative catabolic process GO:1901136 231 0.049
nucleoside phosphate biosynthetic process GO:1901293 79 0.049
cyclic nucleotide metabolic process GO:0009187 59 0.049
negative regulation of protein maturation GO:1903318 79 0.049
Mouse
calcium ion transport GO:0006816 159 0.049
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.048
growth plate cartilage development GO:0003417 14 0.048
negative regulation of hydrolase activity GO:0051346 71 0.048
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.048
heterocycle catabolic process GO:0046700 280 0.048
macromolecule catabolic process GO:0009057 281 0.048
response to growth factor GO:0070848 198 0.047
Mouse
protein maturation GO:0051604 176 0.047
Mouse
regulation of intracellular transport GO:0032386 159 0.047
covalent chromatin modification GO:0016569 163 0.047
Mouse
rho protein signal transduction GO:0007266 32 0.047
ganglion morphogenesis GO:0061552 2 0.047
regulation of cell growth GO:0001558 91 0.047
Mouse
regulation of protein processing GO:0070613 96 0.046
Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.046
positive regulation of ras gtpase activity GO:0032320 65 0.046
myeloid leukocyte activation GO:0002274 83 0.046
ductus arteriosus closure GO:0097070 3 0.046
Mouse
regulation of cytoplasmic transport GO:1903649 112 0.046
positive regulation of chemotaxis GO:0050921 38 0.046
ion transmembrane transport GO:0034220 361 0.046
vascular process in circulatory system GO:0003018 62 0.046
purine nucleoside catabolic process GO:0006152 205 0.045
multicellular organismal homeostasis GO:0048871 164 0.045
defense response to bacterium GO:0042742 119 0.045
chondrocyte hypertrophy GO:0003415 4 0.045
response to extracellular stimulus GO:0009991 127 0.045
Mouse
regulation of hormone levels GO:0010817 211 0.044
negative regulation of defense response GO:0031348 77 0.044
regulation of protein serine threonine kinase activity GO:0071900 157 0.043
cellular homeostasis GO:0019725 240 0.043
regulation of metal ion transport GO:0010959 106 0.043
skeletal system morphogenesis GO:0048705 203 0.043
regulation of nucleotide catabolic process GO:0030811 122 0.043
response to hypoxia GO:0001666 58 0.043
Fly
purine nucleotide biosynthetic process GO:0006164 65 0.043
positive regulation of growth GO:0045927 104 0.043
ribonucleotide catabolic process GO:0009261 208 0.043
neuron death GO:0070997 154 0.043
response to reactive oxygen species GO:0000302 56 0.043
negative regulation of cellular component organization GO:0051129 194 0.043
organonitrogen compound biosynthetic process GO:1901566 192 0.042
negative regulation of neuron apoptotic process GO:0043524 92 0.042
regulation of apoptotic signaling pathway GO:2001233 197 0.042
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.042
purine nucleoside triphosphate metabolic process GO:0009144 226 0.041
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.041
Mouse
postganglionic parasympathetic nervous system development GO:0021784 2 0.041
purine containing compound biosynthetic process GO:0072522 70 0.041
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.041
metanephric glomerular epithelium development GO:0072244 3 0.041
negative regulation of molecular function GO:0044092 258 0.040
Mouse
cation homeostasis GO:0055080 212 0.039
regulation of response to oxidative stress GO:1902882 19 0.039
response to transforming growth factor beta GO:0071559 88 0.039
Mouse
response to oxidative stress GO:0006979 123 0.039
epithelial tube morphogenesis GO:0060562 303 0.038
negative regulation of protein metabolic process GO:0051248 282 0.038
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.038
vasodilation GO:0042311 28 0.038
positive regulation of creb transcription factor activity GO:0032793 4 0.038
heart process GO:0003015 94 0.038
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.038
response to oxygen radical GO:0000305 16 0.037
regulation of cell motility GO:2000145 236 0.037
regulation of system process GO:0044057 200 0.037
thymus development GO:0048538 41 0.037
peptide metabolic process GO:0006518 46 0.037
divalent inorganic cation transport GO:0072511 178 0.037
regulation of endocytosis GO:0030100 69 0.037
myeloid leukocyte differentiation GO:0002573 119 0.037
cellular response to lipid GO:0071396 145 0.037
regulation of ras protein signal transduction GO:0046578 114 0.036
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.036
amide transport GO:0042886 138 0.036
hormone secretion GO:0046879 128 0.036
regulation of transferase activity GO:0051338 263 0.036
cell adhesion GO:0007155 329 0.036
alpha beta t cell activation GO:0046631 91 0.035
cellular macromolecule catabolic process GO:0044265 206 0.035
release of sequestered calcium ion into cytosol GO:0051209 42 0.035
glycosyl compound metabolic process GO:1901657 246 0.035
organonitrogen compound catabolic process GO:1901565 264 0.035
extrinsic apoptotic signaling pathway GO:0097191 126 0.035
transmission of nerve impulse GO:0019226 76 0.035
transmembrane transport GO:0055085 412 0.034
nucleoside triphosphate catabolic process GO:0009143 205 0.034
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.034
negative regulation of phosphate metabolic process GO:0045936 184 0.034
skeletal muscle fiber development GO:0048741 58 0.034
Mouse
regulation of kinase activity GO:0043549 249 0.034
positive regulation of organelle organization GO:0010638 128 0.034
inorganic cation transmembrane transport GO:0098662 207 0.034
anterior commissure morphogenesis GO:0021960 6 0.034
regulation of protein maturation GO:1903317 96 0.034
Mouse
male gamete generation GO:0048232 285 0.034
positive regulation of cell migration GO:0030335 109 0.033
skeletal system development GO:0001501 356 0.033
positive regulation of cell development GO:0010720 237 0.033
regulation of body fluid levels GO:0050878 162 0.033
response to iron ion GO:0010039 4 0.033
stem cell differentiation GO:0048863 268 0.033
regulation of camp metabolic process GO:0030814 30 0.033
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.033
endocrine system development GO:0035270 98 0.033
lateral mesoderm morphogenesis GO:0048369 3 0.033
response to inorganic substance GO:0010035 96 0.033
positive regulation of cell projection organization GO:0031346 95 0.033
regulation of membrane potential GO:0042391 192 0.033
regulation of innate immune response GO:0045088 91 0.033
glycosylation GO:0070085 62 0.032
mitotic cell cycle GO:0000278 195 0.032
cytosolic calcium ion transport GO:0060401 48 0.032
regulation of t cell differentiation GO:0045580 83 0.032
response to radiation GO:0009314 165 0.032
response to insulin GO:0032868 100 0.032
ribonucleoside catabolic process GO:0042454 206 0.032
response to metal ion GO:0010038 47 0.032
positive regulation of apoptotic cell clearance GO:2000427 3 0.032
hindbrain tangential cell migration GO:0021934 2 0.032
connective tissue development GO:0061448 179 0.032
cellular component assembly involved in morphogenesis GO:0010927 139 0.031
cellular ion homeostasis GO:0006873 165 0.031
cytokine mediated signaling pathway GO:0019221 115 0.031
negative regulation of growth GO:0045926 99 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.031
muscle cell development GO:0055001 133 0.031
Mouse
regulation of anti mullerian hormone signaling pathway GO:1902612 1 0.031
detection of light stimulus GO:0009583 25 0.031
cell migration to the midline involved in heart development GO:0003318 1 0.031
regulation of hydrolase activity GO:0051336 246 0.031
Mouse
facioacoustic ganglion development GO:1903375 3 0.031
positive regulation of behavior GO:0048520 40 0.031
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.030
Mouse
vasoconstriction GO:0042310 27 0.030
regulation of t cell activation GO:0050863 170 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.030
glycosyl compound catabolic process GO:1901658 206 0.030
guanosine containing compound metabolic process GO:1901068 144 0.030
myeloid cell differentiation GO:0030099 233 0.030
ossification GO:0001503 216 0.030
nucleoside phosphate catabolic process GO:1901292 222 0.030
regulation of ion homeostasis GO:2000021 64 0.030
facial nerve structural organization GO:0021612 10 0.030
camp biosynthetic process GO:0006171 31 0.030
cyclic purine nucleotide metabolic process GO:0052652 43 0.030
sympathetic neuron projection guidance GO:0097491 4 0.030
regulation of cellular catabolic process GO:0031329 242 0.030
cerebral cortex development GO:0021987 86 0.030
morphogenesis of a branching structure GO:0001763 203 0.029
astrocyte activation GO:0048143 2 0.029
regulation of proteolysis GO:0030162 164 0.029
Mouse
muscle cell differentiation GO:0042692 261 0.029
positive regulation of cell death GO:0010942 224 0.029
beta amyloid metabolic process GO:0050435 14 0.029
positive regulation of cell motility GO:2000147 116 0.029
positive regulation of ion transport GO:0043270 65 0.029
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.029
telencephalon development GO:0021537 186 0.029
regulation of alpha beta t cell activation GO:0046634 53 0.029
positive regulation of cell substrate adhesion GO:0010811 47 0.029
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.029
regulation of endopeptidase activity GO:0052548 89 0.028
Mouse
divalent metal ion transport GO:0070838 172 0.028
tolerance induction to self antigen GO:0002513 4 0.028
calcium ion transport into cytosol GO:0060402 48 0.028
cardiac muscle cell differentiation GO:0055007 69 0.028
Mouse
maintenance of protein location in nucleus GO:0051457 2 0.028
purine ribonucleoside metabolic process GO:0046128 241 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
Mouse
endothelial cell chemotaxis GO:0035767 3 0.028
response to organic cyclic compound GO:0014070 198 0.028
regulation of nucleotide biosynthetic process GO:0030808 34 0.028
cellular response to organonitrogen compound GO:0071417 145 0.027
olfactory nerve development GO:0021553 3 0.027
regulation of neuron death GO:1901214 134 0.027
positive regulation of phagocytosis GO:0050766 26 0.027
cell chemotaxis GO:0060326 81 0.027
positive regulation of cytokine production GO:0001819 174 0.027
positive regulation of neuron differentiation GO:0045666 141 0.027
regulation of protein catabolic process GO:0042176 108 0.027
reactive oxygen species metabolic process GO:0072593 84 0.027
mesenchymal cell development GO:0014031 93 0.027
regulation of muscle adaptation GO:0043502 31 0.027
cardiac muscle fiber development GO:0048739 4 0.027
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.027
response to peptide GO:1901652 136 0.026
cellular amide metabolic process GO:0043603 58 0.026
carboxylic acid biosynthetic process GO:0046394 86 0.026
negative regulation of protein processing GO:0010955 79 0.026
Mouse
actin filament organization GO:0007015 113 0.026
sensory neuron axon guidance GO:0097374 3 0.026
modification dependent protein catabolic process GO:0019941 133 0.026
dendrite development GO:0016358 115 0.026
morphogenesis of a branching epithelium GO:0061138 193 0.026
regulation of cell substrate adhesion GO:0010810 73 0.026
skeletal muscle organ development GO:0060538 163 0.026
Mouse
regulation of organ morphogenesis GO:2000027 144 0.026
cardiac muscle hypertrophy GO:0003300 23 0.026
response to peptide hormone GO:0043434 127 0.026
sympathetic neuron projection extension GO:0097490 4 0.026
cardiac muscle tissue development GO:0048738 130 0.026
cell activation involved in immune response GO:0002263 126 0.026
regulation of neuron differentiation GO:0045664 281 0.026
hypothalamus cell migration GO:0021855 5 0.026
granulocyte chemotaxis GO:0071621 39 0.025
response to light stimulus GO:0009416 135 0.025
regulation of gtp catabolic process GO:0033124 113 0.025
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.025
forebrain development GO:0030900 302 0.025
detection of visible light GO:0009584 14 0.025
lymphocyte differentiation GO:0030098 242 0.025
metanephric glomerular mesangium development GO:0072223 3 0.025
negative regulation of neuron death GO:1901215 98 0.025
regulation of striated muscle cell differentiation GO:0051153 81 0.025
Mouse
regulation of protein kinase activity GO:0045859 232 0.025
regulation of chemotaxis GO:0050920 53 0.025
developmental cell growth GO:0048588 84 0.025
peptidyl tyrosine phosphorylation GO:0018108 143 0.025
positive regulation of muscle hypertrophy GO:0014742 2 0.025
lymphocyte mediated immunity GO:0002449 139 0.024
otic placode formation GO:0043049 1 0.024
cell aging GO:0007569 35 0.024
regulation of lymphocyte activation GO:0051249 240 0.024
cgmp metabolic process GO:0046068 20 0.024
positive regulation of transferase activity GO:0051347 167 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
regulation of peptide transport GO:0090087 91 0.024
positive regulation of protein catabolic process GO:0045732 60 0.024
regulation of cell projection organization GO:0031344 206 0.024
organic hydroxy compound biosynthetic process GO:1901617 77 0.024
meiotic cell cycle GO:0051321 122 0.024
organic acid biosynthetic process GO:0016053 86 0.024
regulation of vasculature development GO:1901342 88 0.024
neuronal action potential GO:0019228 54 0.024
carbohydrate transport GO:0008643 62 0.024
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.023
t cell activation GO:0042110 289 0.023
light adaption GO:0036367 2 0.023
regulation of cellular response to growth factor stimulus GO:0090287 82 0.023
Mouse
phototransduction GO:0007602 17 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.023
plasma membrane organization GO:0007009 90 0.023
bone mineralization GO:0030282 54 0.023
heart contraction GO:0060047 93 0.022
cytosolic calcium ion homeostasis GO:0051480 70 0.022
angiogenesis involved in coronary vascular morphogenesis GO:0060978 2 0.022
cellular response to steroid hormone stimulus GO:0071383 33 0.022
negative regulation of neuron differentiation GO:0045665 101 0.022
metanephric glomerular endothelium development GO:0072264 1 0.022
positive regulation of nucleotide catabolic process GO:0030813 88 0.022
peptide hormone secretion GO:0030072 109 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.022
Mouse
semaphorin plexin signaling pathway GO:0071526 21 0.022
positive regulation of secretion by cell GO:1903532 114 0.022
leukocyte migration GO:0050900 124 0.022
epidermis development GO:0008544 187 0.022
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.022
somitogenesis GO:0001756 69 0.022
neuron projection guidance GO:0097485 141 0.022
positive regulation of tolerance induction to self antigen GO:0002651 1 0.022
positive regulation of cell growth GO:0030307 33 0.022
atp metabolic process GO:0046034 75 0.022
positive chemotaxis GO:0050918 18 0.021
retinal ganglion cell axon guidance GO:0031290 18 0.021
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.021
regulation of hormone secretion GO:0046883 88 0.021
muscle fiber development GO:0048747 76 0.021
Mouse
response to cholesterol GO:0070723 4 0.021
purine containing compound catabolic process GO:0072523 213 0.021
erythrocyte differentiation GO:0030218 88 0.021
organic hydroxy compound transport GO:0015850 93 0.021
divalent inorganic cation homeostasis GO:0072507 138 0.021
atrial septum primum morphogenesis GO:0003289 3 0.021
blastocyst development GO:0001824 80 0.021
ear development GO:0043583 200 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
negative regulation of axon extension GO:0030517 19 0.021
negative regulation of cell motility GO:2000146 61 0.021
dichotomous subdivision of terminal units involved in salivary gland branching GO:0060666 5 0.021
mesoderm structural organization GO:0048338 1 0.021
negative regulation of nervous system development GO:0051961 156 0.021
regulation of calcium ion transport GO:0051924 69 0.021
positive regulation of t cell activation GO:0050870 101 0.020
mesenchyme development GO:0060485 152 0.020
multicellular organismal signaling GO:0035637 91 0.020
cardiac muscle contraction GO:0060048 32 0.020
anatomical structure homeostasis GO:0060249 145 0.020
leukocyte mediated immunity GO:0002443 174 0.020
organelle assembly GO:0070925 177 0.020
pallium development GO:0021543 120 0.020
regulation of calcium ion transport into cytosol GO:0010522 31 0.020
regulation of cytokine production GO:0001817 266 0.020
stress activated protein kinase signaling cascade GO:0031098 81 0.020
vagus nerve morphogenesis GO:0021644 2 0.020
monosaccharide transport GO:0015749 58 0.020
midgut development GO:0007494 4 0.020
vascular smooth muscle contraction GO:0014829 5 0.020
immune effector process GO:0002252 321 0.020
mesendoderm development GO:0048382 3 0.020
trunk segmentation GO:0035290 4 0.020
developmental maturation GO:0021700 193 0.020
regulation of protein localization GO:0032880 231 0.020
development of primary sexual characteristics GO:0045137 143 0.020
cellular response to external stimulus GO:0071496 88 0.020
Mouse
regulation of ph GO:0006885 26 0.020
lateral mesodermal cell differentiation GO:0048371 3 0.020
cell maturation GO:0048469 127 0.020
mesodermal cell migration GO:0008078 4 0.020
Fly
regulation of transmembrane transport GO:0034762 128 0.020
multi multicellular organism process GO:0044706 109 0.020
small molecule biosynthetic process GO:0044283 132 0.019
response to steroid hormone GO:0048545 56 0.019

Mkl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.091
disease of anatomical entity DOID:7 0 0.091
nervous system disease DOID:863 0 0.091
musculoskeletal system disease DOID:17 0 0.036
brain disease DOID:936 0 0.031
connective tissue disease DOID:65 0 0.025
disease of cellular proliferation DOID:14566 0 0.023
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.021