Mus musculus

42 known processes

Mknk1

MAP kinase-interacting serine/threonine kinase 1

(Aliases: 2410048M24Rik,Mnk1)

Mknk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to arsenic containing substance GO:0071243 4 0.875
response to peptide GO:1901652 136 0.395
amine metabolic process GO:0009308 45 0.369
ras protein signal transduction GO:0007265 77 0.341
Fly
carbohydrate metabolic process GO:0005975 230 0.319
peptidyl serine modification GO:0018209 83 0.287
Human Rat
cellular response to cadmium ion GO:0071276 3 0.236
myotube differentiation GO:0014902 105 0.219
establishment of protein localization to organelle GO:0072594 118 0.172
cellular response to molecule of bacterial origin GO:0071219 83 0.170
positive regulation of protein phosphorylation GO:0001934 242 0.169
cellular lipid metabolic process GO:0044255 323 0.162
oxidation reduction process GO:0055114 342 0.159
positive regulation of brown fat cell differentiation GO:0090336 4 0.157
cellular amine metabolic process GO:0044106 44 0.157
peptidyl amino acid modification GO:0018193 336 0.155
Human Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.151
wound healing GO:0042060 157 0.150
cellular response to biotic stimulus GO:0071216 92 0.142
homeostasis of number of cells GO:0048872 210 0.136
fatty acid metabolic process GO:0006631 121 0.136
monocarboxylic acid metabolic process GO:0032787 191 0.128
regulation of protein localization GO:0032880 231 0.128
regulation of apoptotic signaling pathway GO:2001233 197 0.126
positive regulation of cell death GO:0010942 224 0.126
cytoplasmic transport GO:0016482 234 0.126
reactive oxygen species metabolic process GO:0072593 84 0.124
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.121
response to oxidative stress GO:0006979 123 0.121
dna metabolic process GO:0006259 303 0.120
response to organonitrogen compound GO:0010243 246 0.120
protein localization to organelle GO:0033365 185 0.117
cellular response to lipopolysaccharide GO:0071222 77 0.116
myeloid cell differentiation GO:0030099 233 0.114
response to extracellular stimulus GO:0009991 127 0.113
regulation of cellular amino acid metabolic process GO:0006521 5 0.113
response to growth factor GO:0070848 198 0.113
myeloid cell homeostasis GO:0002262 114 0.112
apoptotic signaling pathway GO:0097190 306 0.111
erythrocyte differentiation GO:0030218 88 0.109
cellular response to cytokine stimulus GO:0071345 189 0.108
nuclear transport GO:0051169 139 0.107
cellular response to growth factor stimulus GO:0071363 197 0.105
osmosensory signaling pathway GO:0007231 1 0.104
response to peptide hormone GO:0043434 127 0.102
single organism nuclear import GO:1902593 95 0.101
nucleocytoplasmic transport GO:0006913 139 0.101
positive regulation of apoptotic process GO:0043065 217 0.101
response to molecule of bacterial origin GO:0002237 143 0.100
regulation of cellular amine metabolic process GO:0033238 20 0.099
cell junction maintenance GO:0034331 4 0.098
lipid modification GO:0030258 65 0.098
peptidyl threonine modification GO:0018210 31 0.098
cellular response to oxidative stress GO:0034599 76 0.095
cellular amino acid metabolic process GO:0006520 103 0.095
p38mapk cascade GO:0038066 4 0.093
peptidyl threonine phosphorylation GO:0018107 31 0.091
cation transport GO:0006812 399 0.091
aromatic compound catabolic process GO:0019439 286 0.091
nucleobase containing small molecule metabolic process GO:0055086 352 0.091
cartilage development GO:0051216 140 0.091
regionalization GO:0003002 337 0.091
wnt signaling pathway GO:0016055 188 0.089
positive regulation of cellular amine metabolic process GO:0033240 5 0.087
muscle cell differentiation GO:0042692 261 0.086
mapk cascade GO:0000165 281 0.086
positive regulation of apoptotic signaling pathway GO:2001235 95 0.085
nuclear import GO:0051170 95 0.083
bmp signaling pathway GO:0030509 93 0.083
regulation of innate immune response GO:0045088 91 0.083
small gtpase mediated signal transduction GO:0007264 97 0.082
Fly
skeletal system development GO:0001501 356 0.082
response to nutrient levels GO:0031667 109 0.081
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.080
regulation of cell cycle GO:0051726 281 0.079
response to starvation GO:0042594 65 0.079
rho protein signal transduction GO:0007266 32 0.078
glycosyl compound metabolic process GO:1901657 246 0.077
regulation of anatomical structure size GO:0090066 178 0.077
development of primary sexual characteristics GO:0045137 143 0.075
cellular response to inorganic substance GO:0071241 37 0.074
regulation of ras protein signal transduction GO:0046578 114 0.073
Fly
intracellular protein transport GO:0006886 204 0.073
jun phosphorylation GO:0007258 41 0.073
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.073
positive regulation of intracellular transport GO:0032388 70 0.072
monosaccharide metabolic process GO:0005996 106 0.072
protein import GO:0017038 101 0.072
signal transduction in absence of ligand GO:0038034 55 0.072
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.071
connective tissue development GO:0061448 179 0.070
adherens junction maintenance GO:0034334 1 0.068
positive regulation of protein modification process GO:0031401 299 0.067
regulation of nuclear cell cycle dna replication GO:0033262 2 0.067
peptidyl serine phosphorylation GO:0018105 74 0.066
Human Rat
macromolecule catabolic process GO:0009057 281 0.066
cellular ketone metabolic process GO:0042180 84 0.065
regulation of intracellular transport GO:0032386 159 0.065
purine containing compound metabolic process GO:0072521 311 0.064
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.064
striated muscle tissue development GO:0014706 293 0.063
membrane organization GO:0061024 245 0.063
regulation of protein transport GO:0051223 163 0.063
leukocyte differentiation GO:0002521 342 0.062
cellular response to osmotic stress GO:0071470 7 0.061
protein import into nucleus GO:0006606 95 0.061
regulation of cellular ketone metabolic process GO:0010565 66 0.061
regulation of intracellular protein transport GO:0033157 82 0.060
posttranscriptional regulation of gene expression GO:0010608 155 0.060
Rat
chromatin organization GO:0006325 206 0.060
cellular response to organonitrogen compound GO:0071417 145 0.059
protein targeting GO:0006605 143 0.059
cytokine production GO:0001816 319 0.058
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.056
cellular response to peptide GO:1901653 92 0.056
response to inorganic substance GO:0010035 96 0.055
nucleotide metabolic process GO:0009117 332 0.055
hexose metabolic process GO:0019318 98 0.055
myeloid leukocyte differentiation GO:0002573 119 0.055
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.055
organonitrogen compound catabolic process GO:1901565 264 0.054
cell type specific apoptotic process GO:0097285 268 0.053
regulation of response to drug GO:2001023 2 0.053
glycoprotein biosynthetic process GO:0009101 89 0.052
brown fat cell differentiation GO:0050873 36 0.052
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.052
response to metal ion GO:0010038 47 0.052
regulation of muscle tissue development GO:1901861 97 0.051
cellular response to dna damage stimulus GO:0006974 207 0.051
organic cyclic compound catabolic process GO:1901361 295 0.051
regulation of erythrocyte differentiation GO:0045646 23 0.051
organophosphate catabolic process GO:0046434 232 0.051
ribonucleoside catabolic process GO:0042454 206 0.050
endocytosis GO:0006897 168 0.050
chondrocyte differentiation GO:0002062 72 0.050
positive regulation of intracellular protein transport GO:0090316 42 0.049
positive regulation of cell development GO:0010720 237 0.048
skeletal system morphogenesis GO:0048705 203 0.048
angiogenesis GO:0001525 201 0.048
negative regulation of immune system process GO:0002683 209 0.047
transmembrane transport GO:0055085 412 0.047
regulation of terminal button organization GO:2000331 1 0.047
cellular nitrogen compound catabolic process GO:0044270 280 0.046
fat cell differentiation GO:0045444 160 0.046
regulation of cellular response to stress GO:0080135 159 0.046
positive regulation of protein transport GO:0051222 93 0.046
response to lipopolysaccharide GO:0032496 128 0.045
glucose metabolic process GO:0006006 92 0.045
response to transforming growth factor beta GO:0071559 88 0.045
positive regulation of cell activation GO:0050867 158 0.045
nucleoside metabolic process GO:0009116 246 0.045
engulfment of apoptotic cell GO:0043652 3 0.045
cytokine mediated signaling pathway GO:0019221 115 0.045
regulation of cellular component size GO:0032535 121 0.045
regulation of bmp signaling pathway GO:0030510 60 0.045
positive regulation of organelle organization GO:0010638 128 0.044
negative regulation of intracellular signal transduction GO:1902532 167 0.044
Fly
regulation of antimicrobial humoral response GO:0002759 3 0.044
glycoprotein metabolic process GO:0009100 116 0.044
nucleoside triphosphate metabolic process GO:0009141 230 0.043
protein localization to nucleus GO:0034504 121 0.043
learning or memory GO:0007611 148 0.043
germ cell development GO:0007281 185 0.043
gland development GO:0048732 330 0.043
multicellular organism growth GO:0035264 161 0.043
regulation of protein kinase activity GO:0045859 232 0.043
response to oxygen radical GO:0000305 16 0.043
purine nucleotide metabolic process GO:0006163 302 0.042
canonical wnt signaling pathway GO:0060070 130 0.042
negative regulation of phosphorylation GO:0042326 166 0.042
regulation of cytokine production GO:0001817 266 0.042
regulation of organelle organization GO:0033043 289 0.042
cellular response to extracellular stimulus GO:0031668 81 0.041
extrinsic apoptotic signaling pathway GO:0097191 126 0.041
carbohydrate derivative catabolic process GO:1901136 231 0.041
purine nucleoside triphosphate metabolic process GO:0009144 226 0.041
placenta development GO:0001890 140 0.040
regulation of defense response GO:0031347 233 0.040
positive regulation of determination of dorsal identity GO:2000017 2 0.040
purine nucleotide catabolic process GO:0006195 211 0.040
positive regulation of necrotic cell death GO:0010940 1 0.040
t cell activation GO:0042110 289 0.040
synaptic transmission GO:0007268 329 0.039
ion transmembrane transport GO:0034220 361 0.039
carbohydrate derivative biosynthetic process GO:1901137 183 0.039
synaptic vesicle localization GO:0097479 59 0.039
positive regulation of programmed cell death GO:0043068 218 0.039
glycerolipid metabolic process GO:0046486 122 0.039
cellular response to metal ion GO:0071248 31 0.038
negative regulation of cellular component organization GO:0051129 194 0.038
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.038
ribonucleotide metabolic process GO:0009259 291 0.038
response to epidermal growth factor GO:0070849 4 0.038
embryonic organ morphogenesis GO:0048562 276 0.037
spermatogenesis GO:0007283 284 0.037
regulation of homeostatic process GO:0032844 182 0.037
syncytium formation by plasma membrane fusion GO:0000768 42 0.037
mitotic cell cycle GO:0000278 195 0.037
gonad development GO:0008406 141 0.037
blood vessel morphogenesis GO:0048514 285 0.037
regulation of cytoplasmic transport GO:1903649 112 0.037
immune response regulating signaling pathway GO:0002764 125 0.037
organic hydroxy compound metabolic process GO:1901615 203 0.037
purine containing compound catabolic process GO:0072523 213 0.037
blood circulation GO:0008015 195 0.037
activation of immune response GO:0002253 138 0.037
cellular response to lipid GO:0071396 145 0.037
response to insulin GO:0032868 100 0.036
embryonic placenta development GO:0001892 98 0.036
guanosine containing compound metabolic process GO:1901068 144 0.036
skeletal muscle organ development GO:0060538 163 0.036
regulation of wnt signaling pathway GO:0030111 123 0.036
nuclear division GO:0000280 158 0.036
negative regulation of transposition GO:0010529 2 0.035
protein modification by small protein conjugation GO:0032446 187 0.035
ribonucleoside metabolic process GO:0009119 245 0.035
regulation of cellular catabolic process GO:0031329 242 0.035
positive regulation of homeostatic process GO:0032846 64 0.035
antigen receptor mediated signaling pathway GO:0050851 64 0.034
regulation of mapk cascade GO:0043408 248 0.034
regulation of cell cycle process GO:0010564 160 0.034
regulation of establishment of protein localization GO:0070201 181 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.033
regulation of nucleocytoplasmic transport GO:0046822 73 0.033
skeletal muscle fiber development GO:0048741 58 0.033
glycosyl compound catabolic process GO:1901658 206 0.033
reactive oxygen species biosynthetic process GO:1903409 8 0.033
nucleoside catabolic process GO:0009164 206 0.033
positive regulation of transferase activity GO:0051347 167 0.033
establishment of vesicle localization GO:0051650 81 0.033
peptidyl tyrosine phosphorylation GO:0018108 143 0.033
genitalia development GO:0048806 37 0.032
axonogenesis GO:0007409 274 0.032
muscle tissue development GO:0060537 308 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
cation transmembrane transport GO:0098655 266 0.032
response to cadmium ion GO:0046686 8 0.032
innate immune response GO:0045087 157 0.032
cellular response to insulin stimulus GO:0032869 78 0.032
ossification GO:0001503 216 0.032
heterocycle catabolic process GO:0046700 280 0.031
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.031
response to nitric oxide GO:0071731 4 0.031
cell cell junction organization GO:0045216 72 0.031
paracrine signaling GO:0038001 1 0.031
response to superoxide GO:0000303 16 0.031
regulation of hydrolase activity GO:0051336 246 0.031
positive regulation of kinase activity GO:0033674 155 0.031
cation homeostasis GO:0055080 212 0.031
regulation of cytoskeleton organization GO:0051493 122 0.031
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.031
endomembrane system organization GO:0010256 147 0.031
regulation of purine nucleotide metabolic process GO:1900542 169 0.031
actin cytoskeleton organization GO:0030036 220 0.031
regulation of cell size GO:0008361 72 0.031
cognition GO:0050890 149 0.030
regulation of ras gtpase activity GO:0032318 88 0.030
immune effector process GO:0002252 321 0.030
osteoclast differentiation GO:0030316 62 0.030
hyperosmotic response GO:0006972 4 0.030
positive regulation of myeloid cell differentiation GO:0045639 43 0.030
cellular response to hormone stimulus GO:0032870 150 0.030
phagocytosis GO:0006909 66 0.030
lipid catabolic process GO:0016042 69 0.030
regeneration GO:0031099 38 0.030
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.029
phospholipid metabolic process GO:0006644 87 0.029
glycerophospholipid metabolic process GO:0006650 71 0.029
nucleoside triphosphate catabolic process GO:0009143 205 0.029
terminal button organization GO:0072553 3 0.029
establishment of synaptic vesicle localization GO:0097480 57 0.029
divalent metal ion transport GO:0070838 172 0.028
peptidyl tyrosine modification GO:0018212 145 0.028
positive regulation of mapk cascade GO:0043410 170 0.028
positive regulation of growth GO:0045927 104 0.028
cellular response to granulocyte macrophage colony stimulating factor stimulus GO:0097011 3 0.028
membrane tubulation GO:0097320 4 0.028
regulation of vesicle mediated transport GO:0060627 139 0.028
mitochondrion organization GO:0007005 134 0.027
regulation of actin cytoskeleton organization GO:0032956 84 0.027
cell adhesion GO:0007155 329 0.027
nucleotide catabolic process GO:0009166 217 0.027
purine nucleoside triphosphate catabolic process GO:0009146 203 0.027
defense response to other organism GO:0098542 197 0.027
spermatid development GO:0007286 108 0.027
negative regulation of phosphate metabolic process GO:0045936 184 0.027
cellular homeostasis GO:0019725 240 0.027
protein processing GO:0016485 163 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
epithelial cell proliferation GO:0050673 174 0.026
regulation of transferase activity GO:0051338 263 0.026
icosanoid metabolic process GO:0006690 33 0.026
dna replication GO:0006260 52 0.026
positive regulation of cellular catabolic process GO:0031331 148 0.026
muscle fiber development GO:0048747 76 0.026
alcohol metabolic process GO:0006066 116 0.026
skeletal muscle tissue regeneration GO:0043403 20 0.026
positive regulation of nucleotide catabolic process GO:0030813 88 0.025
cellular response to starvation GO:0009267 57 0.025
extracellular matrix organization GO:0030198 147 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.025
glucose transport GO:0015758 56 0.025
protein modification by small protein conjugation or removal GO:0070647 207 0.025
lipid biosynthetic process GO:0008610 179 0.025
compound eye development GO:0048749 1 0.025
positive regulation of protein kinase activity GO:0045860 144 0.024
negative regulation of multi organism process GO:0043901 68 0.024
male gamete generation GO:0048232 285 0.024
extracellular structure organization GO:0043062 148 0.024
syncytium formation GO:0006949 43 0.024
inflammatory response GO:0006954 244 0.024
regulation of kinase activity GO:0043549 249 0.024
organelle fission GO:0048285 170 0.024
purine ribonucleotide metabolic process GO:0009150 290 0.023
regulation of nucleotide catabolic process GO:0030811 122 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
negative regulation of apoptotic signaling pathway GO:2001234 104 0.023
positive regulation of nervous system development GO:0051962 221 0.023
regulation of cell activation GO:0050865 289 0.023
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.023
lymphocyte proliferation GO:0046651 164 0.023
protein polymerization GO:0051258 57 0.023
cellular response to abiotic stimulus GO:0071214 56 0.023
regulation of multi organism process GO:0043900 111 0.023
digestive tract morphogenesis GO:0048546 147 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
protein ubiquitination GO:0016567 171 0.022
protein catabolic process GO:0030163 221 0.022
lymphocyte differentiation GO:0030098 242 0.022
divalent inorganic cation transport GO:0072511 178 0.022
regulation of endocytosis GO:0030100 69 0.022
positive regulation of protein export from nucleus GO:0046827 4 0.022
regulation of rho protein signal transduction GO:0035023 71 0.022
protein autophosphorylation GO:0046777 61 0.022
response to acid chemical GO:0001101 111 0.022
cell substrate adhesion GO:0031589 130 0.022
chromatin modification GO:0016568 187 0.022
macromolecule methylation GO:0043414 120 0.022
regulation of cell migration GO:0030334 219 0.022
negative regulation of cell development GO:0010721 169 0.022
nitrogen compound transport GO:0071705 271 0.021
nuclear dna replication GO:0033260 3 0.021
response to arsenic containing substance GO:0046685 5 0.021
regulation of protein targeting GO:1903533 61 0.021
meiotic cell cycle GO:0051321 122 0.021
single organism cell adhesion GO:0098602 156 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
covalent chromatin modification GO:0016569 163 0.021
leukocyte migration GO:0050900 124 0.021
leukocyte homeostasis GO:0001776 79 0.021
cellular response to nutrient levels GO:0031669 64 0.021
microglia development GO:0014005 2 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
positive regulation of gtpase activity GO:0043547 85 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
immune response activating signal transduction GO:0002757 116 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
regulation of membrane potential GO:0042391 192 0.021
sensory organ morphogenesis GO:0090596 242 0.021
regulation of mitotic cell cycle GO:0007346 126 0.020
cellular calcium ion homeostasis GO:0006874 119 0.020
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.020
epithelial tube morphogenesis GO:0060562 303 0.020
adult behavior GO:0030534 135 0.020
regulation of response to wounding GO:1903034 189 0.020
regulation of cell projection organization GO:0031344 206 0.020
response to ethanol GO:0045471 18 0.020
vesicle localization GO:0051648 86 0.020
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.020
stress activated protein kinase signaling cascade GO:0031098 81 0.020
sensory perception GO:0007600 245 0.020
lymphocyte homeostasis GO:0002260 64 0.020
negative regulation of nervous system development GO:0051961 156 0.020
cell junction organization GO:0034330 77 0.020
positive regulation of myotube differentiation GO:0010831 24 0.020
defense response to bacterium GO:0042742 119 0.020
cellular response to peptide hormone stimulus GO:0071375 92 0.020
response to reactive oxygen species GO:0000302 56 0.020
defense response to fungus GO:0050832 12 0.020
positive regulation of cell cycle GO:0045787 92 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
female gamete generation GO:0007292 74 0.019
striated muscle cell development GO:0055002 125 0.019
tissue regeneration GO:0042246 22 0.019
macromolecule glycosylation GO:0043413 55 0.019
negative regulation of wnt signaling pathway GO:0030178 73 0.019
regulation of purine nucleotide catabolic process GO:0033121 122 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
synaptic vesicle transport GO:0048489 57 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
lipid oxidation GO:0034440 29 0.019
negative regulation of ras protein signal transduction GO:0046580 18 0.019
Fly
glycosylation GO:0070085 62 0.019
regulation of alpha beta t cell differentiation GO:0046637 35 0.019
myoblast differentiation GO:0045445 52 0.018
sequestering of metal ion GO:0051238 19 0.018
intracellular receptor signaling pathway GO:0030522 74 0.018
positive regulation of erythrocyte differentiation GO:0045648 11 0.018
apical constriction GO:0003383 4 0.018
regulation of myotube differentiation GO:0010830 62 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
calcium ion transport GO:0006816 159 0.018
negative regulation of protein phosphorylation GO:0001933 126 0.018
cellular carbohydrate metabolic process GO:0044262 119 0.018
regulation of neuron differentiation GO:0045664 281 0.018
single organismal cell cell adhesion GO:0016337 131 0.018
organelle localization GO:0051640 179 0.018
regulation of transmembrane transport GO:0034762 128 0.018
jnk cascade GO:0007254 72 0.018
regulation of cellular response to oxidative stress GO:1900407 19 0.018
muscle cell development GO:0055001 133 0.018
regulation of secretion GO:0051046 274 0.018
necrotic cell death GO:0070265 30 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
cellular ion homeostasis GO:0006873 165 0.018
labyrinthine layer blood vessel development GO:0060716 21 0.018
regulation of nucleoside metabolic process GO:0009118 130 0.018
regulation of cell adhesion GO:0030155 154 0.018
maintenance of location GO:0051235 89 0.018
myeloid leukocyte activation GO:0002274 83 0.018
positive regulation of cell motility GO:2000147 116 0.017
organelle assembly GO:0070925 177 0.017
histone modification GO:0016570 159 0.017
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.017
regulation of cysteine type endopeptidase activity GO:2000116 65 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
labyrinthine layer development GO:0060711 49 0.017
lysosome organization GO:0007040 21 0.017
positive regulation of cytokine production GO:0001819 174 0.017
photoreceptor cell differentiation GO:0046530 52 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.017
regulation of neuron death GO:1901214 134 0.017
protein oligomerization GO:0051259 67 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
synapse organization GO:0050808 125 0.017
inositol phosphate catabolic process GO:0071545 4 0.017
multicellular organismal aging GO:0010259 24 0.017
gastrulation GO:0007369 116 0.017
dendritic spine maintenance GO:0097062 4 0.017
multi multicellular organism process GO:0044706 109 0.017
regulation of myoblast differentiation GO:0045661 29 0.017
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.017
oogenesis GO:0048477 56 0.017
generation of precursor metabolites and energy GO:0006091 103 0.017
positive regulation of muscle cell differentiation GO:0051149 39 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
regulation of dna templated transcription in response to stress GO:0043620 9 0.016
response to osmotic stress GO:0006970 21 0.016
mitotic cell cycle process GO:1903047 159 0.016
regulation of secretion by cell GO:1903530 249 0.016
cellular component maintenance GO:0043954 11 0.016
erk1 and erk2 cascade GO:0070371 77 0.016
cell division GO:0051301 120 0.016
segmentation GO:0035282 93 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
positive regulation of cytoplasmic transport GO:1903651 40 0.016
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.016
regulation of gtp catabolic process GO:0033124 113 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.016
membrane lipid metabolic process GO:0006643 53 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
anatomical structure homeostasis GO:0060249 145 0.016
fatty acid oxidation GO:0019395 28 0.016
glycerolipid biosynthetic process GO:0045017 50 0.016
positive regulation of gtp catabolic process GO:0033126 85 0.016
translation GO:0006412 93 0.016
Rat
protein maturation GO:0051604 176 0.016
regulation of neurotransmitter levels GO:0001505 87 0.015
regulation of leukocyte mediated immunity GO:0002703 104 0.015
neural tube development GO:0021915 160 0.015
regulation of chromatin modification GO:1903308 57 0.015
small molecule catabolic process GO:0044282 71 0.015
myeloid leukocyte mediated immunity GO:0002444 42 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
response to temperature stimulus GO:0009266 55 0.015
conditioned taste aversion GO:0001661 4 0.015
regulation of response to oxidative stress GO:1902882 19 0.015
myotube cell development GO:0014904 60 0.015
neuronal action potential GO:0019228 54 0.015
stress activated mapk cascade GO:0051403 80 0.015

Mknk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.047
disease of anatomical entity DOID:7 0 0.047
musculoskeletal system disease DOID:17 0 0.046
immune system disease DOID:2914 0 0.023
disease of metabolism DOID:0014667 0 0.023
connective tissue disease DOID:65 0 0.020
myopathy DOID:423 0 0.017
muscle tissue disease DOID:66 0 0.017
muscular disease DOID:0080000 0 0.017
inherited metabolic disorder DOID:655 0 0.017
central nervous system disease DOID:331 0 0.016