Mus musculus

38 known processes

Mknk2

MAP kinase-interacting serine/threonine kinase 2

(Aliases: Mnk2,Gprk7,2010016G11Rik)

Mknk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
p38mapk cascade GO:0038066 4 0.837
fatty acid metabolic process GO:0006631 121 0.687
cellular response to cadmium ion GO:0071276 3 0.675
monocarboxylic acid metabolic process GO:0032787 191 0.573
oxidation reduction process GO:0055114 342 0.517
protein localization to nucleus GO:0034504 121 0.420
cellular response to biotic stimulus GO:0071216 92 0.406
response to oxygen radical GO:0000305 16 0.405
cellular response to molecule of bacterial origin GO:0071219 83 0.377
response to oxidative stress GO:0006979 123 0.377
cellular response to lipid GO:0071396 145 0.367
cellular response to lipopolysaccharide GO:0071222 77 0.367
response to osmotic stress GO:0006970 21 0.361
Mouse
single organism nuclear import GO:1902593 95 0.356
cellular response to nitric oxide GO:0071732 4 0.355
peptidyl amino acid modification GO:0018193 336 0.345
response to peptide GO:1901652 136 0.344
cellular response to dna damage stimulus GO:0006974 207 0.340
defense response to bacterium GO:0042742 119 0.337
translation GO:0006412 93 0.335
response to organonitrogen compound GO:0010243 246 0.332
positive regulation of protein phosphorylation GO:0001934 242 0.323
cellular response to oxidative stress GO:0034599 76 0.317
protein import GO:0017038 101 0.310
positive regulation of apoptotic process GO:0043065 217 0.297
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.296
cellular lipid metabolic process GO:0044255 323 0.289
response to superoxide GO:0000303 16 0.282
response to molecule of bacterial origin GO:0002237 143 0.273
regulation of cellular response to stress GO:0080135 159 0.271
response to nitric oxide GO:0071731 4 0.264
protein localization to organelle GO:0033365 185 0.259
stress activated protein kinase signaling cascade GO:0031098 81 0.257
response to reactive oxygen species GO:0000302 56 0.255
cellular ketone metabolic process GO:0042180 84 0.251
connective tissue development GO:0061448 179 0.249
wound healing GO:0042060 157 0.247
positive regulation of protein transport GO:0051222 93 0.247
myeloid cell differentiation GO:0030099 233 0.246
regulation of defense response GO:0031347 233 0.246
regulation of myeloid cell differentiation GO:0045637 96 0.236
cellular response to arsenic containing substance GO:0071243 4 0.235
Human
cellular response to inorganic substance GO:0071241 37 0.231
positive regulation of protein modification process GO:0031401 299 0.230
establishment of protein localization to organelle GO:0072594 118 0.227
regulation of protein localization GO:0032880 231 0.226
regulation of protein transport GO:0051223 163 0.226
response to arsenic containing substance GO:0046685 5 0.223
Human
peptidyl threonine phosphorylation GO:0018107 31 0.222
regulation of cell cycle process GO:0010564 160 0.221
peptidyl serine modification GO:0018209 83 0.213
nuclear transport GO:0051169 139 0.211
regulation of antimicrobial humoral response GO:0002759 3 0.211
positive regulation of intracellular transport GO:0032388 70 0.209
positive regulation of apoptotic signaling pathway GO:2001235 95 0.207
regulation of cellular amino acid metabolic process GO:0006521 5 0.206
regulation of innate immune response GO:0045088 91 0.201
regulation of myotube differentiation GO:0010830 62 0.201
regulation of intracellular protein transport GO:0033157 82 0.196
nucleocytoplasmic transport GO:0006913 139 0.195
myeloid cell homeostasis GO:0002262 114 0.194
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.190
regulation of nuclear cell cycle dna replication GO:0033262 2 0.189
defense response to other organism GO:0098542 197 0.189
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.189
fatty acid oxidation GO:0019395 28 0.188
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.187
cytoplasmic transport GO:0016482 234 0.187
leukocyte differentiation GO:0002521 342 0.184
regulation of translation GO:0006417 71 0.182
regulation of establishment of protein localization GO:0070201 181 0.180
response to lipopolysaccharide GO:0032496 128 0.179
jnk cascade GO:0007254 72 0.179
positive regulation of cytoplasmic transport GO:1903651 40 0.174
peptidyl threonine modification GO:0018210 31 0.172
bmp signaling pathway GO:0030509 93 0.172
posttranscriptional regulation of gene expression GO:0010608 155 0.170
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.164
cellular response to osmotic stress GO:0071470 7 0.162
positive regulation of protein export from nucleus GO:0046827 4 0.162
stress activated mapk cascade GO:0051403 80 0.159
positive regulation of cellular amine metabolic process GO:0033240 5 0.159
wnt signaling pathway GO:0016055 188 0.158
mapk cascade GO:0000165 281 0.157
defense response to gram positive bacterium GO:0050830 50 0.157
cellular response to organonitrogen compound GO:0071417 145 0.155
negative regulation of phosphate metabolic process GO:0045936 184 0.155
regulation of cellular catabolic process GO:0031329 242 0.151
peptidyl serine phosphorylation GO:0018105 74 0.150
positive regulation of cell death GO:0010942 224 0.147
intracellular protein transport GO:0006886 204 0.147
immune response activating signal transduction GO:0002757 116 0.144
homeostasis of number of cells GO:0048872 210 0.144
ossification GO:0001503 216 0.142
apoptotic signaling pathway GO:0097190 306 0.142
negative regulation of phosphorus metabolic process GO:0010563 184 0.139
inflammatory response GO:0006954 244 0.136
cellular amino acid metabolic process GO:0006520 103 0.136
cytokine production GO:0001816 319 0.135
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.134
cellular response to growth factor stimulus GO:0071363 197 0.133
protein import into nucleus GO:0006606 95 0.133
response to growth factor GO:0070848 198 0.133
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.132
regulation of cellular ketone metabolic process GO:0010565 66 0.132
regulation of intracellular transport GO:0032386 159 0.131
multicellular organism growth GO:0035264 161 0.131
negative regulation of phosphorylation GO:0042326 166 0.130
jun phosphorylation GO:0007258 41 0.129
osteoclast differentiation GO:0030316 62 0.128
myeloid leukocyte differentiation GO:0002573 119 0.128
lipid oxidation GO:0034440 29 0.128
response to nutrient levels GO:0031667 109 0.127
skeletal muscle fiber development GO:0048741 58 0.126
protein targeting GO:0006605 143 0.125
osmosensory signaling pathway GO:0007231 1 0.123
striated muscle tissue development GO:0014706 293 0.123
regulation of multi organism process GO:0043900 111 0.123
amine metabolic process GO:0009308 45 0.122
myotube differentiation GO:0014902 105 0.121
positive regulation of mapk cascade GO:0043410 170 0.121
regulation of cytoplasmic transport GO:1903649 112 0.119
cartilage development GO:0051216 140 0.117
positive regulation of growth GO:0045927 104 0.116
innate immune response GO:0045087 157 0.114
reactive oxygen species metabolic process GO:0072593 84 0.113
regulation of response to biotic stimulus GO:0002831 38 0.113
regulation of nucleocytoplasmic transport GO:0046822 73 0.112
development of primary sexual characteristics GO:0045137 143 0.112
nuclear import GO:0051170 95 0.111
paracrine signaling GO:0038001 1 0.110
multicellular organismal aging GO:0010259 24 0.109
negative regulation of immune system process GO:0002683 209 0.109
negative regulation of intracellular signal transduction GO:1902532 167 0.108
Fly
monosaccharide metabolic process GO:0005996 106 0.107
heterocycle catabolic process GO:0046700 280 0.107
lipid modification GO:0030258 65 0.107
activation of immune response GO:0002253 138 0.107
regulation of cellular amine metabolic process GO:0033238 20 0.106
muscle cell differentiation GO:0042692 261 0.105
regulation of response to wounding GO:1903034 189 0.105
ras protein signal transduction GO:0007265 77 0.104
Fly
regulation of apoptotic signaling pathway GO:2001233 197 0.104
positive regulation of determination of dorsal identity GO:2000017 2 0.102
cellular response to peptide GO:1901653 92 0.102
carbohydrate metabolic process GO:0005975 230 0.102
cellular response to hormone stimulus GO:0032870 150 0.101
regulation of protein targeting GO:1903533 61 0.101
peptidyl lysine modification GO:0018205 77 0.101
dna metabolic process GO:0006259 303 0.100
immune response regulating signaling pathway GO:0002764 125 0.100
skeletal system development GO:0001501 356 0.100
regulation of homeostatic process GO:0032844 182 0.096
positive regulation of intracellular protein transport GO:0090316 42 0.096
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.095
erythrocyte differentiation GO:0030218 88 0.094
necrotic cell death GO:0070265 30 0.094
small gtpase mediated signal transduction GO:0007264 97 0.094
Fly
brown fat cell differentiation GO:0050873 36 0.093
negative regulation of cell proliferation GO:0008285 296 0.093
regulation of bmp signaling pathway GO:0030510 60 0.092
small molecule catabolic process GO:0044282 71 0.090
negative regulation of wnt signaling pathway GO:0030178 73 0.088
regulation of mapk cascade GO:0043408 248 0.087
response to extracellular stimulus GO:0009991 127 0.086
negative regulation of molecular function GO:0044092 258 0.086
peptidyl tyrosine modification GO:0018212 145 0.085
muscle tissue development GO:0060537 308 0.082
nucleotide metabolic process GO:0009117 332 0.082
regulation of fat cell differentiation GO:0045598 81 0.081
male gamete generation GO:0048232 285 0.081
regulation of cellular component size GO:0032535 121 0.079
glucose metabolic process GO:0006006 92 0.077
cellular response to peptide hormone stimulus GO:0071375 92 0.076
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.076
response to peptide hormone GO:0043434 127 0.076
organelle fission GO:0048285 170 0.075
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.075
regulation of dna templated transcription in response to stress GO:0043620 9 0.074
cellular response to cytokine stimulus GO:0071345 189 0.074
nucleobase containing small molecule metabolic process GO:0055086 352 0.073
syncytium formation by plasma membrane fusion GO:0000768 42 0.073
response to epidermal growth factor GO:0070849 4 0.073
hyperosmotic response GO:0006972 4 0.073
cytokine metabolic process GO:0042107 71 0.073
gonad development GO:0008406 141 0.071
cellular amine metabolic process GO:0044106 44 0.069
chromatin modification GO:0016568 187 0.069
cellular response to granulocyte macrophage colony stimulating factor stimulus GO:0097011 3 0.068
positive regulation of response to wounding GO:1903036 66 0.068
microtubule based process GO:0007017 236 0.067
Fly
purine nucleotide metabolic process GO:0006163 302 0.067
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.067
translational initiation GO:0006413 24 0.065
syncytium formation GO:0006949 43 0.065
response to starvation GO:0042594 65 0.064
regulation of cell cycle GO:0051726 281 0.064
cellular lipid catabolic process GO:0044242 52 0.064
cellular response to salt stress GO:0071472 1 0.064
regulation of wound healing GO:0061041 40 0.063
regulation of wnt signaling pathway GO:0030111 123 0.062
aromatic compound catabolic process GO:0019439 286 0.062
positive regulation of cellular catabolic process GO:0031331 148 0.062
regulation of erythrocyte differentiation GO:0045646 23 0.062
cellular response to acid chemical GO:0071229 68 0.062
regulation of skeletal muscle fiber development GO:0048742 36 0.062
regulation of terminal button organization GO:2000331 1 0.061
muscle cell development GO:0055001 133 0.061
embryonic placenta development GO:0001892 98 0.060
regulation of cytokine production GO:0001817 266 0.060
skeletal system morphogenesis GO:0048705 203 0.060
chondrocyte differentiation GO:0002062 72 0.059
cell cell junction organization GO:0045216 72 0.059
gland development GO:0048732 330 0.059
germ cell development GO:0007281 185 0.058
defense response to gram negative bacterium GO:0050829 28 0.057
cell type specific apoptotic process GO:0097285 268 0.057
nuclear dna replication GO:0033260 3 0.057
response to cadmium ion GO:0046686 8 0.056
fat cell differentiation GO:0045444 160 0.056
canonical wnt signaling pathway GO:0060070 130 0.056
regulation of muscle tissue development GO:1901861 97 0.055
i kappab kinase nf kappab signaling GO:0007249 85 0.055
regulation of reproductive process GO:2000241 66 0.055
ribonucleotide metabolic process GO:0009259 291 0.055
regulation of canonical wnt signaling pathway GO:0060828 82 0.055
neuronal action potential GO:0019228 54 0.054
determination of adult lifespan GO:0008340 11 0.053
nucleoside triphosphate catabolic process GO:0009143 205 0.052
regulation of nucleotide metabolic process GO:0006140 169 0.052
purine nucleoside triphosphate catabolic process GO:0009146 203 0.052
negative regulation of protein phosphorylation GO:0001933 126 0.052
cell junction organization GO:0034330 77 0.052
response to inorganic substance GO:0010035 96 0.051
regulation of protein serine threonine kinase activity GO:0071900 157 0.051
mitotic cell cycle GO:0000278 195 0.051
regulation of striated muscle cell differentiation GO:0051153 81 0.051
positive regulation of innate immune response GO:0045089 80 0.051
endomembrane system organization GO:0010256 147 0.050
lipid catabolic process GO:0016042 69 0.050
multicellular organismal signaling GO:0035637 91 0.050
regulation of protein kinase activity GO:0045859 232 0.050
macromolecule catabolic process GO:0009057 281 0.050
regulation of autophagy GO:0010506 30 0.049
generation of precursor metabolites and energy GO:0006091 103 0.049
nuclear division GO:0000280 158 0.049
regulation of response to drug GO:2001023 2 0.048
intrinsic apoptotic signaling pathway GO:0097193 132 0.048
epithelial cell proliferation GO:0050673 174 0.048
synaptic transmission GO:0007268 329 0.048
cellular response to reactive nitrogen species GO:1902170 5 0.048
positive regulation of homeostatic process GO:0032846 64 0.048
response to organic cyclic compound GO:0014070 198 0.048
negative regulation of protein metabolic process GO:0051248 282 0.048
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.047
mitochondrion organization GO:0007005 134 0.047
cellular response to insulin stimulus GO:0032869 78 0.047
regulation of protein binding GO:0043393 60 0.046
regulation of cytokine biosynthetic process GO:0042035 59 0.046
macroautophagy GO:0016236 21 0.046
action potential GO:0001508 78 0.045
negative regulation of mapk cascade GO:0043409 65 0.045
hexose metabolic process GO:0019318 98 0.045
maintenance of location GO:0051235 89 0.045
organic cyclic compound catabolic process GO:1901361 295 0.045
cellular macromolecule catabolic process GO:0044265 206 0.045
labyrinthine layer blood vessel development GO:0060716 21 0.045
regulation of cell activation GO:0050865 289 0.044
regulation of translational initiation GO:0006446 15 0.044
positive regulation of kinase activity GO:0033674 155 0.044
cytokine biosynthetic process GO:0042089 68 0.044
ribonucleotide catabolic process GO:0009261 208 0.044
mitotic cell cycle process GO:1903047 159 0.044
circulatory system process GO:0003013 197 0.044
energy derivation by oxidation of organic compounds GO:0015980 77 0.044
regulation of determination of dorsal identity GO:2000015 3 0.043
regulation of myoblast differentiation GO:0045661 29 0.043
blood vessel morphogenesis GO:0048514 285 0.043
nucleoside phosphate metabolic process GO:0006753 338 0.043
autophagy GO:0006914 45 0.043
morphogenesis of a branching structure GO:0001763 203 0.042
monocarboxylic acid catabolic process GO:0072329 27 0.042
terminal button organization GO:0072553 3 0.042
ribonucleoside triphosphate metabolic process GO:0009199 220 0.042
regulation of secretion GO:0051046 274 0.042
regulation of organelle organization GO:0033043 289 0.041
positive regulation of myotube differentiation GO:0010831 24 0.041
cell cycle switching GO:0060184 1 0.041
regulation of organ morphogenesis GO:2000027 144 0.041
regulation of mitotic cell cycle GO:0007346 126 0.041
carbohydrate derivative catabolic process GO:1901136 231 0.041
cation transport GO:0006812 399 0.041
negative regulation of myeloid cell differentiation GO:0045638 38 0.040
fatty acid transmembrane transport GO:1902001 1 0.040
organonitrogen compound catabolic process GO:1901565 264 0.040
carbohydrate derivative biosynthetic process GO:1901137 183 0.040
carboxylic acid catabolic process GO:0046395 51 0.040
regulation of membrane potential GO:0042391 192 0.039
dna damage checkpoint GO:0000077 26 0.039
regionalization GO:0003002 337 0.039
purine nucleotide catabolic process GO:0006195 211 0.039
respiratory tube development GO:0030323 167 0.039
cellular response to metal ion GO:0071248 31 0.039
multi multicellular organism process GO:0044706 109 0.039
transmission of nerve impulse GO:0019226 76 0.038
internal protein amino acid acetylation GO:0006475 42 0.038
purine nucleoside metabolic process GO:0042278 241 0.038
regulation of kinase activity GO:0043549 249 0.038
lipid biosynthetic process GO:0008610 179 0.038
nucleoside phosphate catabolic process GO:1901292 222 0.038
regulation of chromosome organization GO:0033044 83 0.038
positive regulation of protein kinase activity GO:0045860 144 0.038
cell maturation GO:0048469 127 0.038
t cell differentiation GO:0030217 174 0.037
response to metal ion GO:0010038 47 0.037
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.037
purine containing compound metabolic process GO:0072521 311 0.037
negative regulation of humoral immune response GO:0002921 6 0.037
regulation of jnk cascade GO:0046328 62 0.037
activation of mapk activity involved in innate immune response GO:0035419 2 0.037
purine containing compound catabolic process GO:0072523 213 0.037
cellular homeostasis GO:0019725 240 0.037
regulation of chromatin organization GO:1902275 57 0.036
labyrinthine layer development GO:0060711 49 0.036
activation of innate immune response GO:0002218 56 0.036
blood circulation GO:0008015 195 0.036
glycosyl compound metabolic process GO:1901657 246 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
positive regulation of protein localization to nucleus GO:1900182 30 0.036
actin cytoskeleton organization GO:0030036 220 0.035
lymphocyte differentiation GO:0030098 242 0.035
regulation of stress activated mapk cascade GO:0032872 69 0.035
regulation of leukocyte differentiation GO:1902105 159 0.034
axon ensheathment GO:0008366 76 0.034
placenta development GO:0001890 140 0.034
hormone secretion GO:0046879 128 0.034
anion transmembrane transport GO:0098656 71 0.034
negative regulation of cellular catabolic process GO:0031330 47 0.034
mammary gland epithelial cell proliferation GO:0033598 24 0.034
angiogenesis GO:0001525 201 0.034
regulation of protein targeting to membrane GO:0090313 9 0.033
genitalia development GO:0048806 37 0.033
positive regulation of programmed cell death GO:0043068 218 0.033
spermatid differentiation GO:0048515 115 0.033
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.033
negative regulation of mitotic cell cycle GO:0045930 58 0.033
multicellular organismal homeostasis GO:0048871 164 0.033
heart contraction GO:0060047 93 0.032
oogenesis GO:0048477 56 0.032
muscle system process GO:0003012 141 0.032
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.032
negative regulation of cell fate specification GO:0009996 4 0.032
regulation of secretion by cell GO:1903530 249 0.032
meiotic cell cycle GO:0051321 122 0.032
organic acid catabolic process GO:0016054 51 0.031
glycogen metabolic process GO:0005977 32 0.031
lipid localization GO:0010876 126 0.031
regulation of fatty acid beta oxidation GO:0031998 1 0.030
negative regulation of multi organism process GO:0043901 68 0.030
spermatogenesis GO:0007283 284 0.030
regulation of fatty acid metabolic process GO:0019217 28 0.030
regulation of lipid metabolic process GO:0019216 118 0.030
response to transforming growth factor beta GO:0071559 88 0.030
regulation of protein import into nucleus GO:0042306 52 0.030
rhythmic process GO:0048511 174 0.030
interleukin 1 mediated signaling pathway GO:0070498 4 0.030
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.030
polysaccharide metabolic process GO:0005976 39 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
response to insulin GO:0032868 100 0.030
regulation of hormone levels GO:0010817 211 0.030
regulation of insulin receptor signaling pathway GO:0046626 21 0.030
positive regulation of defense response GO:0031349 124 0.030
neuron death GO:0070997 154 0.029
cellular response to abiotic stimulus GO:0071214 56 0.029
negative regulation of nervous system development GO:0051961 156 0.029
peptidyl lysine acetylation GO:0018394 45 0.029
negative regulation of transposition GO:0010529 2 0.029
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
intracellular receptor signaling pathway GO:0030522 74 0.029
anion transport GO:0006820 177 0.029
developmental maturation GO:0021700 193 0.029
insulin receptor signaling pathway GO:0008286 49 0.029
myoblast differentiation GO:0045445 52 0.029
protein autophosphorylation GO:0046777 61 0.028
antigen receptor mediated signaling pathway GO:0050851 64 0.028
circadian rhythm GO:0007623 114 0.028
regulation of cell size GO:0008361 72 0.028
dna integrity checkpoint GO:0031570 28 0.028
cellular carbohydrate metabolic process GO:0044262 119 0.028
positive regulation of histone modification GO:0031058 28 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.028
regulation of jun kinase activity GO:0043506 40 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
negative regulation of cellular amine metabolic process GO:0033239 1 0.028
skeletal muscle organ development GO:0060538 163 0.028
ribonucleoside metabolic process GO:0009119 245 0.027
regulation of proteolysis GO:0030162 164 0.027
cellular response to organic cyclic compound GO:0071407 87 0.027
positive regulation of cytokine production GO:0001819 174 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
protein modification by small protein conjugation GO:0032446 187 0.027
stem cell maintenance GO:0019827 130 0.027
dna replication GO:0006260 52 0.027
g protein coupled receptor signaling pathway GO:0007186 243 0.027
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.027
regulation of map kinase activity GO:0043405 120 0.027
myotube cell development GO:0014904 60 0.027
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.026
regulation of cell migration GO:0030334 219 0.026
response to temperature stimulus GO:0009266 55 0.026
positive regulation of nervous system development GO:0051962 221 0.026
positive regulation of organelle organization GO:0010638 128 0.026
regeneration GO:0031099 38 0.026
glucose homeostasis GO:0042593 128 0.026
response to monosaccharide GO:0034284 67 0.026
nitrogen compound transport GO:0071705 271 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.025
covalent chromatin modification GO:0016569 163 0.025
protein acylation GO:0043543 64 0.025
response to acid chemical GO:0001101 111 0.025
cell adhesion GO:0007155 329 0.025
regulation of cellular response to oxidative stress GO:1900407 19 0.025
regulation of response to oxidative stress GO:1902882 19 0.025
programmed necrotic cell death GO:0097300 28 0.025
lipid storage GO:0019915 36 0.025
nucleotide catabolic process GO:0009166 217 0.025
regulation of reactive oxygen species metabolic process GO:2000377 40 0.025
positive regulation of lipid storage GO:0010884 10 0.025
female gamete generation GO:0007292 74 0.025
humoral immune response GO:0006959 57 0.025
lymphocyte proliferation GO:0046651 164 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
regulation of system process GO:0044057 200 0.025
regulation of lipid biosynthetic process GO:0046890 54 0.024
positive regulation of fatty acid oxidation GO:0046321 4 0.024
cellular response to extracellular stimulus GO:0031668 81 0.024
regulation of nucleotide catabolic process GO:0030811 122 0.024
striated muscle cell development GO:0055002 125 0.024
negative regulation of ossification GO:0030279 49 0.024
nucleoside metabolic process GO:0009116 246 0.024
chromatin organization GO:0006325 206 0.024
internal peptidyl lysine acetylation GO:0018393 42 0.024
skeletal muscle tissue regeneration GO:0043403 20 0.024
protein catabolic process GO:0030163 221 0.024
compound eye development GO:0048749 1 0.024
fatty acid beta oxidation GO:0006635 16 0.024
protein kinase b signaling GO:0043491 74 0.024
positive regulation of reproductive process GO:2000243 19 0.023
regulation of ras protein signal transduction GO:0046578 114 0.023
Fly
protein processing GO:0016485 163 0.023
positive regulation of cell migration GO:0030335 109 0.023
positive regulation of fat cell differentiation GO:0045600 32 0.023
regulation of tight junction assembly GO:2000810 2 0.023
regulation of hippo signaling GO:0035330 1 0.023
regulation of osteoblast differentiation GO:0045667 67 0.023
positive regulation of myeloid cell differentiation GO:0045639 43 0.023
regulation of neuron death GO:1901214 134 0.023
carbohydrate homeostasis GO:0033500 128 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
glucan biosynthetic process GO:0009250 14 0.022
stem cell development GO:0048864 219 0.022
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.022
protein export from nucleus GO:0006611 20 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
response to oxygen levels GO:0070482 62 0.022
positive regulation of cell cycle GO:0045787 92 0.022
regulation of lymphocyte activation GO:0051249 240 0.022
protein polymerization GO:0051258 57 0.022
negative regulation of homeostatic process GO:0032845 71 0.022
b cell receptor signaling pathway GO:0050853 20 0.022
gtp metabolic process GO:0046039 144 0.021
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.021
protein localization to membrane GO:0072657 108 0.021
oocyte maturation GO:0001556 18 0.021
glycerolipid metabolic process GO:0046486 122 0.021
mammary gland epithelium development GO:0061180 65 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
regulation of anatomical structure size GO:0090066 178 0.021
regulation of protein catabolic process GO:0042176 108 0.021
muscle contraction GO:0006936 101 0.021
regulation of t cell activation GO:0050863 170 0.021
monocarboxylic acid transport GO:0015718 44 0.021
gliogenesis GO:0042063 141 0.021
interleukin 5 secretion GO:0072603 2 0.021
fatty acid catabolic process GO:0009062 25 0.021
modification by symbiont of host morphology or physiology GO:0044003 4 0.021
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.021
methylation GO:0032259 134 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
positive regulation of triglyceride metabolic process GO:0090208 9 0.020
histone modification GO:0016570 159 0.020
multi organism behavior GO:0051705 62 0.020
myelination GO:0042552 74 0.020
cellular glucan metabolic process GO:0006073 32 0.020
regulation of binding GO:0051098 111 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
regulation of brown fat cell differentiation GO:0090335 5 0.020

Mknk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.028