Mus musculus

111 known processes

Mmp14

matrix metallopeptidase 14 (membrane-inserted)

(Aliases: AI325305,MT-MMP-1,MT1-MMP)

Mmp14 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal system development GO:0001501 356 1.000
angiogenesis GO:0001525 201 0.993
Rat
extracellular matrix organization GO:0030198 147 0.991
axon guidance GO:0007411 141 0.987
Zebrafish
bone development GO:0060348 120 0.981
chondrocyte differentiation GO:0002062 72 0.980
skeletal system morphogenesis GO:0048705 203 0.979
connective tissue development GO:0061448 179 0.971
Zebrafish
appendage morphogenesis GO:0035107 149 0.952
extrinsic apoptotic signaling pathway GO:0097191 126 0.951
extracellular structure organization GO:0043062 148 0.949
axonogenesis GO:0007409 274 0.936
Zebrafish
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.936
gland development GO:0048732 330 0.935
formation of radial glial scaffolds GO:0021943 4 0.930
regulation of apoptotic signaling pathway GO:2001233 197 0.918
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.910
cellular response to amino acid stimulus GO:0071230 29 0.905
bone morphogenesis GO:0060349 78 0.901
stem cell development GO:0048864 219 0.893
Mouse
stem cell maintenance GO:0019827 130 0.879
Mouse
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.871
digestive tract morphogenesis GO:0048546 147 0.868
Human Zebrafish
cartilage development GO:0051216 140 0.864
Zebrafish
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.850
limb development GO:0060173 166 0.845
face morphogenesis GO:0060325 29 0.840
digestive system development GO:0055123 200 0.835
Human Zebrafish
small gtpase mediated signal transduction GO:0007264 97 0.831
ossification GO:0001503 216 0.823
regulation of fat cell differentiation GO:0045598 81 0.819
chondrocyte development GO:0002063 24 0.813
apoptotic signaling pathway GO:0097190 306 0.813
protein catabolic process GO:0030163 221 0.803
odontogenesis GO:0042476 78 0.801
endochondral bone morphogenesis GO:0060350 50 0.796
positive regulation of nervous system development GO:0051962 221 0.793
signal transduction in absence of ligand GO:0038034 55 0.790
blood vessel morphogenesis GO:0048514 285 0.787
Rat
digestive tract development GO:0048565 190 0.782
Human Zebrafish
regulation of mapk cascade GO:0043408 248 0.777
gastrulation GO:0007369 116 0.772
Human Zebrafish
regulation of cell adhesion GO:0030155 154 0.759
Rat
embryonic skeletal system morphogenesis GO:0048704 91 0.757
ribonucleotide metabolic process GO:0009259 291 0.751
collagen fibril organization GO:0030199 32 0.750
developmental maturation GO:0021700 193 0.747
positive regulation of programmed cell death GO:0043068 218 0.746
neuron projection guidance GO:0097485 141 0.743
Zebrafish
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.742
multicellular organismal homeostasis GO:0048871 164 0.735
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.733
morphogenesis of a branching structure GO:0001763 203 0.703
chemotaxis GO:0006935 247 0.701
Zebrafish
ovulation cycle GO:0042698 59 0.694
Rat
anatomical structure maturation GO:0071695 49 0.694
cellular response to growth factor stimulus GO:0071363 197 0.689
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.683
organonitrogen compound biosynthetic process GO:1901566 192 0.668
neural crest cell migration GO:0001755 32 0.668
negative regulation of cell proliferation GO:0008285 296 0.666
negative regulation of cell development GO:0010721 169 0.664
positive regulation of apoptotic process GO:0043065 217 0.662
pallium development GO:0021543 120 0.657
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.657
regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000159 1 0.652
multicellular organismal catabolic process GO:0044243 7 0.645
bone trabecula morphogenesis GO:0061430 12 0.644
head morphogenesis GO:0060323 34 0.638
morphogenesis of a branching epithelium GO:0061138 193 0.634
negative regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000160 1 0.627
regulation of proteolysis GO:0030162 164 0.626
Rat
regulation of cell migration GO:0030334 219 0.623
Human
ras protein signal transduction GO:0007265 77 0.612
macromolecule catabolic process GO:0009057 281 0.611
endoderm formation GO:0001706 20 0.607
Human
regulation of platelet derived growth factor receptor beta signaling pathway GO:2000586 2 0.600
hair follicle morphogenesis GO:0031069 29 0.599
negative regulation of immune system process GO:0002683 209 0.598
prostate gland morphogenesis GO:0060512 32 0.590
negative regulation of cell migration GO:0030336 59 0.586
response to acid chemical GO:0001101 111 0.582
anatomical structure homeostasis GO:0060249 145 0.570
regulation of map kinase activity GO:0043405 120 0.566
negative regulation of apoptotic signaling pathway GO:2001234 104 0.565
response to amino acid GO:0043200 37 0.565
nucleotide metabolic process GO:0009117 332 0.564
peptidyl amino acid modification GO:0018193 336 0.556
embryonic skeletal system development GO:0048706 120 0.552
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.549
cell adhesion GO:0007155 329 0.549
Mouse Rat
odontogenesis of dentin containing tooth GO:0042475 66 0.548
fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 2 0.546
negative regulation of intracellular signal transduction GO:1902532 167 0.546
stem cell differentiation GO:0048863 268 0.544
Mouse
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.540
growth plate cartilage development GO:0003417 14 0.539
cartilage condensation GO:0001502 18 0.534
negative regulation of cell cycle GO:0045786 123 0.530
salivary gland morphogenesis GO:0007435 33 0.528
regulation of jak stat cascade GO:0046425 34 0.520
peripheral nervous system axon regeneration GO:0014012 2 0.517
positive regulation of cell migration GO:0030335 109 0.517
Human
forebrain cell migration GO:0021885 58 0.516
cellular response to acid chemical GO:0071229 68 0.510
positive regulation of mapk cascade GO:0043410 170 0.508
purine containing compound metabolic process GO:0072521 311 0.508
oocyte construction GO:0007308 2 0.502
protein localization to nucleus GO:0034504 121 0.496
regulation of protein serine threonine kinase activity GO:0071900 157 0.496
positive regulation of cell motility GO:2000147 116 0.488
Human
ameboidal type cell migration GO:0001667 128 0.488
Zebrafish
cell matrix adhesion GO:0007160 68 0.487
Rat
replacement ossification GO:0036075 26 0.480
regulation of cellular amine metabolic process GO:0033238 20 0.478
cell proliferation in midbrain GO:0033278 2 0.475
ovarian follicle development GO:0001541 40 0.473
Rat
embryonic placenta development GO:0001892 98 0.472
negative regulation of cell adhesion GO:0007162 45 0.468
Rat
cardiac muscle tissue development GO:0048738 130 0.463
cellular ketone metabolic process GO:0042180 84 0.462
purine ribonucleotide metabolic process GO:0009150 290 0.461
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000162 1 0.460
negative regulation of molecular function GO:0044092 258 0.456
gonad development GO:0008406 141 0.454
Rat
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.446
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.445
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000149 1 0.443
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.439
intracellular protein transport GO:0006886 204 0.431
regulation of transferase activity GO:0051338 263 0.430
mammary gland morphogenesis GO:0060443 54 0.428
exocrine system development GO:0035272 45 0.427
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.424
cellular response to lipid GO:0071396 145 0.423
regionalization GO:0003002 337 0.422
Zebrafish
negative regulation of nervous system development GO:0051961 156 0.414
amine metabolic process GO:0009308 45 0.412
regulation of cellular ketone metabolic process GO:0010565 66 0.410
response to growth factor GO:0070848 198 0.409
glial cell differentiation GO:0010001 131 0.409
Mouse
negative regulation of growth GO:0045926 99 0.407
negative regulation of cell motility GO:2000146 61 0.403
response to organonitrogen compound GO:0010243 246 0.401
peptidyl tyrosine phosphorylation GO:0018108 143 0.397
stem cell proliferation GO:0072089 117 0.397
developmental growth involved in morphogenesis GO:0060560 138 0.396
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.395
purine ribonucleoside catabolic process GO:0046130 205 0.392
cellular response to cholesterol GO:0071397 2 0.389
epithelial cell proliferation GO:0050673 174 0.380
Rat
face development GO:0060324 38 0.378
regulation of cell motility GO:2000145 236 0.377
Human
sensory organ morphogenesis GO:0090596 242 0.376
Zebrafish
wound healing GO:0042060 157 0.374
cardiac ventricle development GO:0003231 83 0.372
regulation of cellular response to growth factor stimulus GO:0090287 82 0.370
response to decreased oxygen levels GO:0036293 59 0.367
Zebrafish Rat
regulation of rho protein signal transduction GO:0035023 71 0.356
cardiac chamber development GO:0003205 108 0.355
oocyte axis specification GO:0007309 2 0.354
regulation of ras protein signal transduction GO:0046578 114 0.354
lymphocyte differentiation GO:0030098 242 0.353
negative regulation of protein metabolic process GO:0051248 282 0.353
telencephalon development GO:0021537 186 0.352
single organismal cell cell adhesion GO:0016337 131 0.351
Mouse
endodermal cell differentiation GO:0035987 14 0.348
Human
nuclear transport GO:0051169 139 0.346
neural tube closure GO:0001843 90 0.346
mapk cascade GO:0000165 281 0.345
epidermis morphogenesis GO:0048730 33 0.343
regulation of neuron differentiation GO:0045664 281 0.343
mesenchymal cell differentiation GO:0048762 107 0.341
neuron migration GO:0001764 122 0.338
negative regulation of neuron differentiation GO:0045665 101 0.337
jak stat cascade GO:0007259 42 0.326
protein processing GO:0016485 163 0.326
cellular response to abiotic stimulus GO:0071214 56 0.326
forebrain development GO:0030900 302 0.324
regulation of protein kinase activity GO:0045859 232 0.323
axonogenesis involved in innervation GO:0060385 5 0.321
limb morphogenesis GO:0035108 149 0.321
canonical wnt signaling pathway involved in neural crest cell differentiation GO:0044335 1 0.318
negative regulation of release of cytochrome c from mitochondria GO:0090201 6 0.318
guanosine containing compound catabolic process GO:1901069 144 0.317
nucleobase containing small molecule metabolic process GO:0055086 352 0.317
cardiac muscle tissue morphogenesis GO:0055008 44 0.312
regulation of innate immune response GO:0045088 91 0.310
nucleoside phosphate metabolic process GO:0006753 338 0.308
negative regulation of axon extension GO:0030517 19 0.307
negative regulation of chemotaxis GO:0050922 11 0.305
protein maturation GO:0051604 176 0.299
purine nucleotide metabolic process GO:0006163 302 0.296
response to alcohol GO:0097305 48 0.296
protein import GO:0017038 101 0.295
cellular response to fluid shear stress GO:0071498 4 0.292
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.291
cardiac endothelial cell differentiation GO:0003348 4 0.290
positive regulation of kinase activity GO:0033674 155 0.289
antibacterial peptide secretion GO:0002779 1 0.288
ventricular zone neuroblast division GO:0021847 3 0.286
leukocyte differentiation GO:0002521 342 0.283
oxidation reduction process GO:0055114 342 0.281
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.280
negative regulation of planar cell polarity pathway involved in neural tube closure GO:2000168 1 0.280
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000164 1 0.278
peptide transport GO:0015833 133 0.278
nucleoside triphosphate metabolic process GO:0009141 230 0.276
negative regulation of cardiac muscle tissue development GO:0055026 8 0.276
rho protein signal transduction GO:0007266 32 0.275
glycoprotein metabolic process GO:0009100 116 0.273
regulation of kinase activity GO:0043549 249 0.272
bone trabecula formation GO:0060346 9 0.271
negative regulation of transferase activity GO:0051348 85 0.269
regulation of protein transport GO:0051223 163 0.269
antimicrobial peptide secretion GO:0002776 1 0.269
negative regulation of epithelial cell proliferation GO:0050680 64 0.268
regulation of cellular catabolic process GO:0031329 242 0.267
fat cell differentiation GO:0045444 160 0.267
glycosyl compound metabolic process GO:1901657 246 0.267
regulation of planar cell polarity pathway involved in neural tube closure GO:2000167 1 0.266
protein targeting GO:0006605 143 0.264
striated muscle tissue development GO:0014706 293 0.263
regulation of chondrocyte differentiation GO:0032330 33 0.260
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.259
multicellular organism growth GO:0035264 161 0.258
forebrain radial glial cell differentiation GO:0021861 4 0.258
retinal ganglion cell axon guidance GO:0031290 18 0.258
Zebrafish
luteinization GO:0001553 8 0.256
axis elongation involved in somitogenesis GO:0090245 4 0.256
rhythmic process GO:0048511 174 0.255
Rat
actomyosin structure organization GO:0031032 56 0.254
tissue homeostasis GO:0001894 115 0.251
regulation of cellular amino acid metabolic process GO:0006521 5 0.251
regulation of tissue remodeling GO:0034103 38 0.250
male gamete generation GO:0048232 285 0.246
peptide secretion GO:0002790 114 0.244
regulation of cell cycle GO:0051726 281 0.243
proteoglycan metabolic process GO:0006029 38 0.243
apoptotic process in bone marrow GO:0071839 1 0.241
regulation of osteoblast proliferation GO:0033688 15 0.240
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.240
regulation of ossification GO:0030278 112 0.240
trabecula morphogenesis GO:0061383 40 0.237
response to retinoic acid GO:0032526 56 0.235
negative regulation of platelet derived growth factor receptor beta signaling pathway GO:2000587 2 0.235
muscle tissue development GO:0060537 308 0.233
response to oxygen levels GO:0070482 62 0.232
Zebrafish Rat
appendage development GO:0048736 166 0.231
molting cycle GO:0042303 90 0.231
ribose phosphate metabolic process GO:0019693 291 0.230
prostate gland epithelium morphogenesis GO:0060740 31 0.224
cellular response to cytokine stimulus GO:0071345 189 0.223
cellular response to organic cyclic compound GO:0071407 87 0.223
negative regulation of cellular amine metabolic process GO:0033239 1 0.222
organonitrogen compound catabolic process GO:1901565 264 0.222
gtp catabolic process GO:0006184 143 0.222
keratinocyte proliferation GO:0043616 21 0.222
protein import into nucleus GO:0006606 95 0.218
endoderm development GO:0007492 45 0.218
Human
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.217
cellular amine metabolic process GO:0044106 44 0.216
canonical wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development GO:0061310 1 0.214
positive regulation of cell development GO:0010720 237 0.213
negative regulation of bmp signaling pathway GO:0030514 35 0.212
cell substrate adhesion GO:0031589 130 0.212
Rat
salivary gland development GO:0007431 37 0.211
regulation of anatomical structure size GO:0090066 178 0.210
osteoblast development GO:0002076 17 0.208
cyclic nucleotide metabolic process GO:0009187 59 0.207
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.207
prostate gland development GO:0030850 48 0.207
regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000161 1 0.205
inflammatory response GO:0006954 244 0.203
response to alkaloid GO:0043279 34 0.200
positive regulation of cellular catabolic process GO:0031331 148 0.199
nuclear membrane organization GO:0071763 4 0.199
positive regulation of bone resorption GO:0045780 13 0.198
regulation of organ morphogenesis GO:2000027 144 0.197
regulation of defense response GO:0031347 233 0.196
regulation of stem cell differentiation GO:2000736 50 0.195
forebrain generation of neurons GO:0021872 63 0.195
muscle tissue morphogenesis GO:0060415 53 0.192
cell type specific apoptotic process GO:0097285 268 0.191
cytoplasmic transport GO:0016482 234 0.187
bone maturation GO:0070977 13 0.187
establishment or maintenance of cell polarity GO:0007163 86 0.186
Zebrafish
positive regulation of cell death GO:0010942 224 0.186
spermatogenesis GO:0007283 284 0.184
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.180
glycerolipid metabolic process GO:0046486 122 0.179
carbohydrate homeostasis GO:0033500 128 0.179
mesenchyme development GO:0060485 152 0.179
dna metabolic process GO:0006259 303 0.178
purine ribonucleoside metabolic process GO:0046128 241 0.178
nucleoside metabolic process GO:0009116 246 0.177
hindbrain radial glia guided cell migration GO:0021932 12 0.177
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.176
myeloid leukocyte differentiation GO:0002573 119 0.176
branching involved in salivary gland morphogenesis GO:0060445 26 0.176
wnt signaling pathway GO:0016055 188 0.175
ribonucleoside catabolic process GO:0042454 206 0.174
regulation of osteoblast differentiation GO:0045667 67 0.173
endodermal digestive tract morphogenesis GO:0061031 4 0.172
bone resorption GO:0045453 38 0.171
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.171
action potential GO:0001508 78 0.171
positive regulation of apoptotic signaling pathway GO:2001235 95 0.170
response to fibroblast growth factor GO:0071774 47 0.170
regulation of nucleotide metabolic process GO:0006140 169 0.168
cellular response to alcohol GO:0097306 23 0.168
positive regulation of hydrolase activity GO:0051345 148 0.166
Rat
positive regulation of phospholipase activity GO:0010518 3 0.165
cellular macromolecule catabolic process GO:0044265 206 0.164
cell migration in hindbrain GO:0021535 16 0.164
negative regulation of immature t cell proliferation GO:0033087 3 0.163
activation of mapkk activity GO:0000186 15 0.162
somite specification GO:0001757 4 0.160
regeneration GO:0031099 38 0.159
regulation of cytoskeleton organization GO:0051493 122 0.159
regulation of angiogenesis GO:0045765 81 0.158
negative regulation of ossification GO:0030279 49 0.158
cell chemotaxis GO:0060326 81 0.157
mammary gland bud morphogenesis GO:0060648 4 0.157
synaptic transmission GO:0007268 329 0.157
actin cytoskeleton organization GO:0030036 220 0.155
ensheathment of neurons GO:0007272 76 0.155
regulation of gliogenesis GO:0014013 50 0.155
regulation of purine nucleotide metabolic process GO:1900542 169 0.153
ovulation GO:0030728 15 0.153
oogenesis GO:0048477 56 0.153
purine containing compound biosynthetic process GO:0072522 70 0.152
muscle cell development GO:0055001 133 0.152
cellular response to steroid hormone stimulus GO:0071383 33 0.152
anterior commissure morphogenesis GO:0021960 6 0.151
negative regulation of cell growth GO:0030308 44 0.149
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.149
limbic system development GO:0021761 72 0.148
steroid metabolic process GO:0008202 119 0.147
regulation of cell projection organization GO:0031344 206 0.147
regulation of protein localization GO:0032880 231 0.147
negative regulation of protein maturation GO:1903318 79 0.146
single organism cell adhesion GO:0098602 156 0.146
Mouse
cellular protein catabolic process GO:0044257 155 0.146
nucleoside catabolic process GO:0009164 206 0.146
deltoid tuberosity development GO:0035993 3 0.146
lipid transport GO:0006869 98 0.145
urogenital system development GO:0001655 261 0.145
bone mineralization GO:0030282 54 0.145
astrocyte activation GO:0048143 2 0.145
mucopolysaccharide metabolic process GO:1903510 25 0.144
lipid biosynthetic process GO:0008610 179 0.144
detection of stimulus GO:0051606 84 0.143
Mouse
osteoclast differentiation GO:0030316 62 0.143
regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:2000150 1 0.143
response to inorganic substance GO:0010035 96 0.142
engulfment of apoptotic cell GO:0043652 3 0.141
cardiac septum development GO:0003279 59 0.140
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.139
collagen metabolic process GO:0032963 17 0.138
response to interleukin 1 GO:0070555 11 0.137
cell differentiation involved in embryonic placenta development GO:0060706 26 0.137
cell junction assembly GO:0034329 52 0.137
Rat
retina vasculature development in camera type eye GO:0061298 17 0.136
negative regulation of osteoblast differentiation GO:0045668 30 0.135
gtp metabolic process GO:0046039 144 0.135
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.135
membranous septum morphogenesis GO:0003149 6 0.134
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.133
muscle cell differentiation GO:0042692 261 0.133
skin morphogenesis GO:0043589 38 0.133
skin development GO:0043588 220 0.132
smooth muscle tissue development GO:0048745 22 0.132
cognition GO:0050890 149 0.131
myeloid cell differentiation GO:0030099 233 0.130
response to hyperoxia GO:0055093 2 0.130
regulation of ion transport GO:0043269 215 0.130
regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000165 1 0.129
protein localization to organelle GO:0033365 185 0.128
negative regulation of fat cell differentiation GO:0045599 36 0.128
negative regulation of macrophage chemotaxis GO:0010760 1 0.127
multi multicellular organism process GO:0044706 109 0.127
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.127
cellular response to organonitrogen compound GO:0071417 145 0.126
g protein coupled receptor signaling pathway GO:0007186 243 0.126
circulatory system process GO:0003013 197 0.126
nucleoside phosphate catabolic process GO:1901292 222 0.126
epithelial cell migration GO:0010631 63 0.126
camera type eye development GO:0043010 266 0.125
Zebrafish
embryonic placenta morphogenesis GO:0060669 25 0.124
mitotic cell cycle GO:0000278 195 0.123
regulation of phospholipase a2 activity GO:0032429 3 0.123
hair cycle GO:0042633 90 0.123
regulation of stress activated mapk cascade GO:0032872 69 0.122
positive regulation of cell adhesion GO:0045785 80 0.122
negative regulation of leukocyte proliferation GO:0070664 46 0.122
negative regulation of neuron projection development GO:0010977 50 0.121
response to electrical stimulus GO:0051602 8 0.121
negative regulation of cellular protein metabolic process GO:0032269 247 0.120
primary neural tube formation GO:0014020 95 0.120
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.119
membrane organization GO:0061024 245 0.118
cellular lipid metabolic process GO:0044255 323 0.118
regulation of neuron migration GO:2001222 22 0.117
somitogenesis GO:0001756 69 0.117
prostate glandular acinus morphogenesis GO:0060526 7 0.117
muscle cell migration GO:0014812 19 0.117
limb bud formation GO:0060174 10 0.116
rac protein signal transduction GO:0016601 13 0.116
protein modification by small protein conjugation or removal GO:0070647 207 0.116
innate immune response GO:0045087 157 0.116
negative regulation of phosphorus metabolic process GO:0010563 184 0.115
purine nucleoside metabolic process GO:0042278 241 0.115
negative regulation of cellular component organization GO:0051129 194 0.114
Rat
neuronal action potential GO:0019228 54 0.114
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.114
respiratory system development GO:0060541 190 0.113
renal system development GO:0072001 225 0.112
ribonucleoside metabolic process GO:0009119 245 0.112
regulation of cellular component size GO:0032535 121 0.112
negative regulation of dna replication GO:0008156 4 0.111
regulation of bone mineralization GO:0030500 31 0.111
regulation of astrocyte differentiation GO:0048710 20 0.111
negative regulation of myeloid cell differentiation GO:0045638 38 0.110
organelle assembly GO:0070925 177 0.110
nitrogen compound transport GO:0071705 271 0.110
endochondral bone growth GO:0003416 19 0.110
organ growth GO:0035265 117 0.109
myofibril assembly GO:0030239 34 0.108
epithelial cell development GO:0002064 159 0.107
regulation of wnt signaling pathway GO:0030111 123 0.107
lymphocyte proliferation GO:0046651 164 0.107
negative regulation of astrocyte differentiation GO:0048712 10 0.107
organophosphate biosynthetic process GO:0090407 122 0.107
formation of primary germ layer GO:0001704 77 0.107
Human
hindbrain tangential cell migration GO:0021934 2 0.106
positive regulation of neuron apoptotic process GO:0043525 25 0.106
defense response to gram negative bacterium GO:0050829 28 0.106
axon regeneration GO:0031103 12 0.106
positive regulation of epithelial cell migration GO:0010634 19 0.106
response to hypoxia GO:0001666 58 0.105
Zebrafish Rat
positive regulation of ossification GO:0045778 47 0.105
regulation of organelle organization GO:0033043 289 0.105
positive regulation of transferase activity GO:0051347 167 0.105
astrocyte differentiation GO:0048708 43 0.104
guanosine containing compound metabolic process GO:1901068 144 0.104
negative regulation of lymphocyte activation GO:0051250 91 0.103
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis GO:0060527 7 0.103
mesenchymal epithelial cell signaling GO:0060638 9 0.103
nuclear import GO:0051170 95 0.102
neural crest cell differentiation GO:0014033 54 0.102
amelogenesis GO:0097186 12 0.102
regulation of lipid transport GO:0032368 36 0.101
regulation of chemotaxis GO:0050920 53 0.100
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.099
cardiac right ventricle formation GO:0003219 3 0.098
phosphatidylinositol mediated signaling GO:0048015 41 0.097
hair follicle development GO:0001942 85 0.097
canonical wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation GO:0061324 2 0.097
protein modification by small protein conjugation GO:0032446 187 0.097
endodermal cell fate determination GO:0007493 2 0.097
nucleocytoplasmic transport GO:0006913 139 0.096
mammary gland bud formation GO:0060615 2 0.096
response to radiation GO:0009314 165 0.096
regulation of rho gtpase activity GO:0032319 58 0.096
glucose homeostasis GO:0042593 128 0.095
regulation of mitotic cell cycle GO:0007346 126 0.095
mesenchymal cell development GO:0014031 93 0.095
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.095
regulation of t cell proliferation GO:0042129 92 0.094
carbohydrate derivative biosynthetic process GO:1901137 183 0.094
protein autophosphorylation GO:0046777 61 0.093
negative regulation of kinase activity GO:0033673 81 0.093
regulation of membrane potential GO:0042391 192 0.092
neural precursor cell proliferation GO:0061351 121 0.092
heart morphogenesis GO:0003007 178 0.092
body morphogenesis GO:0010171 45 0.091
central nervous system neuron development GO:0021954 67 0.090
glial cell development GO:0021782 54 0.090
antimicrobial peptide production GO:0002775 2 0.090
biomineral tissue development GO:0031214 64 0.090
positive regulation of protein phosphorylation GO:0001934 242 0.090
production of molecular mediator of immune response GO:0002440 103 0.089

Mmp14 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 1.000
musculoskeletal system disease DOID:17 0 1.000
connective tissue disease DOID:65 0 1.000
bone disease DOID:0080001 0 0.988
bone development disease DOID:0080006 0 0.844
osteochondrodysplasia DOID:2256 0 0.810
disease of cellular proliferation DOID:14566 0 0.581
cancer DOID:162 0 0.465
organ system cancer DOID:0050686 0 0.452
gastrointestinal system cancer DOID:3119 0 0.209
osteogenesis imperfecta DOID:12347 0 0.122
dysostosis DOID:1934 0 0.090