Mus musculus

349 known processes

Msx2

homeobox, msh-like 2

(Aliases: Hox8,Hox-8,BB122635,Hox8.1)

Msx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ morphogenesis GO:0048562 276 1.000
Mouse
regionalization GO:0003002 337 1.000
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 1.000
limb development GO:0060173 166 1.000
stem cell differentiation GO:0048863 268 1.000
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 1.000
stem cell development GO:0048864 219 1.000
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 1.000
skeletal system morphogenesis GO:0048705 203 1.000
appendage development GO:0048736 166 1.000
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.999
bmp signaling pathway GO:0030509 93 0.999
embryonic appendage morphogenesis GO:0035113 126 0.999
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.999
embryonic limb morphogenesis GO:0030326 126 0.999
sensory organ morphogenesis GO:0090596 242 0.999
Mouse
neural tube patterning GO:0021532 43 0.999
limb morphogenesis GO:0035108 149 0.999
cell proliferation in hindbrain GO:0021534 10 0.998
neural tube development GO:0021915 160 0.998
central nervous system neuron differentiation GO:0021953 162 0.998
appendage morphogenesis GO:0035107 149 0.998
neuron projection guidance GO:0097485 141 0.997
epithelial tube morphogenesis GO:0060562 303 0.997
mesenchyme development GO:0060485 152 0.997
neural tube closure GO:0001843 90 0.997
embryonic skeletal system development GO:0048706 120 0.996
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.995
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.995
retinal bipolar neuron differentiation GO:0060040 5 0.994
embryonic skeletal system morphogenesis GO:0048704 91 0.994
axon guidance GO:0007411 141 0.993
cell proliferation in forebrain GO:0021846 30 0.992
trophectodermal cell differentiation GO:0001829 21 0.992
mesenchymal cell development GO:0014031 93 0.992
auditory receptor cell fate determination GO:0042668 3 0.991
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.990
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.990
tendon formation GO:0035992 4 0.990
formation of radial glial scaffolds GO:0021943 4 0.990
pyramidal neuron migration GO:0021852 1 0.989
primary neural tube formation GO:0014020 95 0.989
hindbrain development GO:0030902 128 0.989
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.988
forebrain development GO:0030900 302 0.988
Mouse
positive regulation of stem cell proliferation GO:2000648 59 0.987
axial mesodermal cell fate commitment GO:0048322 1 0.987
telencephalon development GO:0021537 186 0.982
forebrain generation of neurons GO:0021872 63 0.982
camera type eye development GO:0043010 266 0.981
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.981
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.980
formation of primary germ layer GO:0001704 77 0.980
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.979
spinal cord development GO:0021510 81 0.978
stem cell maintenance GO:0019827 130 0.976
skeletal system development GO:0001501 356 0.975
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.975
regulation of bmp signaling pathway GO:0030510 60 0.975
forebrain neuron differentiation GO:0021879 52 0.974
renal system development GO:0072001 225 0.973
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.972
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.972
neuroblast differentiation GO:0014016 2 0.972
floor plate morphogenesis GO:0033505 3 0.972
epidermis morphogenesis GO:0048730 33 0.971
forebrain cell migration GO:0021885 58 0.970
cell fate commitment GO:0045165 210 0.970
Fly
regulation of endodermal cell fate specification GO:0042663 2 0.967
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.966
cerebellar granule cell precursor proliferation GO:0021930 10 0.965
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.964
nerve development GO:0021675 67 0.963
left lung development GO:0060459 4 0.962
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.962
trophectodermal cellular morphogenesis GO:0001831 3 0.962
negative regulation of keratinocyte differentiation GO:0045617 4 0.960
endodermal cell fate specification GO:0001714 4 0.959
axonogenesis GO:0007409 274 0.959
diencephalon development GO:0021536 63 0.958
endodermal cell fate commitment GO:0001711 12 0.958
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.958
globus pallidus development GO:0021759 2 0.958
embryonic heart tube formation GO:0003144 1 0.958
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.957
somitogenesis GO:0001756 69 0.957
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.956
skin morphogenesis GO:0043589 38 0.955
mesenchymal stem cell maintenance involved in nephron morphogenesis GO:0072038 7 0.952
pallium development GO:0021543 120 0.951
dorsal ventral neural tube patterning GO:0021904 28 0.950
mesenchymal cell differentiation GO:0048762 107 0.950
neural crest formation GO:0014029 2 0.947
gastrulation GO:0007369 116 0.946
ear morphogenesis GO:0042471 118 0.945
Mouse
molting cycle GO:0042303 90 0.944
odontogenesis GO:0042476 78 0.943
epidermis development GO:0008544 187 0.943
ear development GO:0043583 200 0.942
Mouse
muscle tissue development GO:0060537 308 0.940
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.938
olfactory bulb development GO:0021772 30 0.937
neural tube formation GO:0001841 108 0.936
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.936
hypophysis morphogenesis GO:0048850 3 0.934
hair follicle development GO:0001942 85 0.932
epithelial to mesenchymal transition GO:0001837 47 0.931
metencephalon development GO:0022037 89 0.931
pituitary gland development GO:0021983 38 0.926
trachea cartilage morphogenesis GO:0060535 4 0.925
apoptotic process involved in morphogenesis GO:0060561 25 0.924
mesodermal cell fate commitment GO:0001710 17 0.924
forebrain radial glial cell differentiation GO:0021861 4 0.922
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.922
forelimb morphogenesis GO:0035136 40 0.920
regulation of organ morphogenesis GO:2000027 144 0.919
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.919
lung induction GO:0060492 3 0.918
skin development GO:0043588 220 0.918
axis elongation involved in somitogenesis GO:0090245 4 0.918
embryonic digit morphogenesis GO:0042733 56 0.918
embryonic camera type eye development GO:0031076 36 0.917
somatic stem cell maintenance GO:0035019 47 0.916
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.915
regulation of stem cell maintenance GO:2000036 17 0.912
cerebral cortex neuron differentiation GO:0021895 19 0.911
olfactory bulb interneuron development GO:0021891 7 0.908
embryonic nail plate morphogenesis GO:0035880 3 0.907
kidney epithelium development GO:0072073 121 0.905
hindlimb morphogenesis GO:0035137 42 0.904
telencephalon cell migration GO:0022029 55 0.903
locus ceruleus development GO:0021703 1 0.903
embryonic eye morphogenesis GO:0048048 29 0.903
regulation of stem cell differentiation GO:2000736 50 0.902
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.900
blastocyst formation GO:0001825 33 0.899
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.899
nephron tubule morphogenesis GO:0072078 68 0.898
regulation of hair follicle development GO:0051797 9 0.897
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.896
cerebral cortex cell migration GO:0021795 44 0.895
cerebral cortex tangential migration GO:0021800 7 0.894
cranial suture morphogenesis GO:0060363 8 0.894
paraxial mesodermal cell fate commitment GO:0048343 2 0.893
epithelial tube formation GO:0072175 130 0.889
limbic system development GO:0021761 72 0.889
central nervous system morphogenesis GO:0021551 2 0.888
forebrain neuron fate commitment GO:0021877 13 0.886
keratinocyte differentiation GO:0030216 48 0.884
spinal cord dorsal ventral patterning GO:0021513 23 0.884
epithelial cell development GO:0002064 159 0.883
cell proliferation in external granule layer GO:0021924 10 0.882
lens morphogenesis in camera type eye GO:0002089 24 0.882
neuroblast fate determination GO:0007400 1 0.881
embryonic forelimb morphogenesis GO:0035115 32 0.879
muscle fiber development GO:0048747 76 0.875
inner ear morphogenesis GO:0042472 101 0.874
roof plate formation GO:0021509 1 0.872
development of primary sexual characteristics GO:0045137 143 0.872
anterior commissure morphogenesis GO:0021960 6 0.871
positive regulation of tendon cell differentiation GO:2001051 1 0.868
chondrocyte differentiation GO:0002062 72 0.864
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.863
stem cell proliferation GO:0072089 117 0.863
Mouse
cell fate specification GO:0001708 72 0.862
Fly
regulation of chondrocyte differentiation GO:0032330 33 0.861
mesoderm development GO:0007498 100 0.853
hemangioblast cell differentiation GO:0060217 1 0.853
gland development GO:0048732 330 0.851
morphogenesis of a branching epithelium GO:0061138 193 0.850
embryonic epithelial tube formation GO:0001838 130 0.849
tube closure GO:0060606 91 0.849
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.849
regulation of leukocyte differentiation GO:1902105 159 0.848
ventral spinal cord interneuron differentiation GO:0021514 16 0.847
embryonic genitalia morphogenesis GO:0030538 4 0.847
oculomotor nerve morphogenesis GO:0021622 2 0.847
male sex differentiation GO:0046661 109 0.847
cell migration in hindbrain GO:0021535 16 0.847
morphogenesis of a branching structure GO:0001763 203 0.845
mesoderm morphogenesis GO:0048332 64 0.845
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.844
renal tubule development GO:0061326 87 0.843
metanephric capsule specification GO:0072267 1 0.842
midbrain hindbrain boundary development GO:0030917 9 0.841
morphogenesis of embryonic epithelium GO:0016331 159 0.839
corticotropin hormone secreting cell differentiation GO:0060128 3 0.838
tendon cell differentiation GO:0035990 4 0.836
olfactory bulb interneuron differentiation GO:0021889 12 0.835
cerebellum development GO:0021549 77 0.833
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.832
olfactory lobe development GO:0021988 32 0.829
regulation of endodermal cell differentiation GO:1903224 2 0.827
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.826
head morphogenesis GO:0060323 34 0.825
Mouse
prostate gland morphogenesis GO:0060512 32 0.825
negative regulation of epithelial cell proliferation GO:0050680 64 0.825
embryonic viscerocranium morphogenesis GO:0048703 8 0.825
inner ear receptor cell differentiation GO:0060113 61 0.823
regulation of muscle tissue development GO:1901861 97 0.823
parasympathetic nervous system development GO:0048486 19 0.820
body morphogenesis GO:0010171 45 0.820
Mouse
hypothalamus development GO:0021854 16 0.818
embryonic skeletal joint morphogenesis GO:0060272 11 0.818
negative regulation of cell development GO:0010721 169 0.817
cardiocyte differentiation GO:0035051 87 0.817
optic vesicle morphogenesis GO:0003404 2 0.815
neuron fate specification GO:0048665 30 0.812
hair follicle morphogenesis GO:0031069 29 0.811
hair cycle GO:0042633 90 0.811
cerebral cortex radially oriented cell migration GO:0021799 31 0.809
negative regulation of neuron differentiation GO:0045665 101 0.807
regulation of heart morphogenesis GO:2000826 22 0.804
cranial nerve development GO:0021545 41 0.800
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.795
axial mesodermal cell fate specification GO:0048327 1 0.794
otic placode formation GO:0043049 1 0.792
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.790
regulation of neural precursor cell proliferation GO:2000177 70 0.789
neural crest cell fate commitment GO:0014034 1 0.789
positive regulation of cell death GO:0010942 224 0.789
regulation of transcription from rna polymerase ii promoter involved in forebrain neuron fate commitment GO:0021882 3 0.787
pancreatic pp cell fate commitment GO:0003329 2 0.787
neural precursor cell proliferation GO:0061351 121 0.787
retinal ganglion cell axon guidance GO:0031290 18 0.786
rostrocaudal neural tube patterning GO:0021903 12 0.786
cerebral cortex gabaergic interneuron fate commitment GO:0021893 2 0.785
lateral motor column neuron migration GO:0097477 3 0.781
hindbrain morphogenesis GO:0021575 46 0.780
mesonephros development GO:0001823 97 0.780
mesoderm formation GO:0001707 62 0.776
midbrain development GO:0030901 35 0.776
Mouse
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.773
germ cell development GO:0007281 185 0.771
Worm
eye photoreceptor cell development GO:0042462 31 0.771
atrial ventricular junction remodeling GO:0003294 2 0.769
forebrain morphogenesis GO:0048853 17 0.767
glial cell differentiation GO:0010001 131 0.766
Fly
regulation of auditory receptor cell differentiation GO:0045607 4 0.765
forebrain anterior posterior pattern specification GO:0021797 5 0.764
forebrain neuron development GO:0021884 30 0.762
cell maturation GO:0048469 127 0.762
cranial nerve morphogenesis GO:0021602 26 0.761
midbrain hindbrain boundary maturation GO:0021732 1 0.758
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.755
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.751
positive regulation of transcription by glucose GO:0046016 3 0.750
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.748
cell differentiation involved in embryonic placenta development GO:0060706 26 0.747
digestive tract development GO:0048565 190 0.747
regulation of apoptotic process involved in morphogenesis GO:1902337 10 0.746
neuron projection extension GO:1990138 64 0.746
cardiac right ventricle formation GO:0003219 3 0.746
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.741
regulation of neuron projection development GO:0010975 169 0.739
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis GO:0060598 2 0.737
paraxial mesodermal cell differentiation GO:0048342 2 0.737
palate development GO:0060021 76 0.736
Mouse
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.733
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.730
cell differentiation in hindbrain GO:0021533 24 0.729
pigmentation GO:0043473 71 0.728
regulation of cell motility GO:2000145 236 0.728
primitive streak formation GO:0090009 10 0.727
negative regulation of apoptotic process involved in morphogenesis GO:1902338 6 0.726
neuroblast proliferation GO:0007405 49 0.723
regulation of neuron differentiation GO:0045664 281 0.723
negative regulation of bmp signaling pathway GO:0030514 35 0.717
epithelial cell morphogenesis GO:0003382 41 0.717
regulation of epithelial to mesenchymal transition GO:0010717 22 0.712
blastocyst development GO:0001824 80 0.712
carbon catabolite repression of transcription GO:0045013 1 0.709
left lung morphogenesis GO:0060460 3 0.708
brain morphogenesis GO:0048854 32 0.705
digestive tract morphogenesis GO:0048546 147 0.705
face morphogenesis GO:0060325 29 0.705
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.703
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.702
regulation of cell migration GO:0030334 219 0.702
mammary placode formation GO:0060596 4 0.698
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.697
positive regulation of cerebellar granule cell precursor proliferation GO:0021940 10 0.696
regulation of cardiac muscle tissue development GO:0055024 31 0.696
positive regulation of nervous system development GO:0051962 221 0.695
regulation of stem cell proliferation GO:0072091 78 0.695
genitalia development GO:0048806 37 0.692
Fly
compound eye development GO:0048749 1 0.692
diterpenoid metabolic process GO:0016101 24 0.691
hair cycle phase GO:0044851 16 0.688
closure of optic fissure GO:0061386 2 0.686
tube formation GO:0035148 140 0.685
gonad development GO:0008406 141 0.684
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.683
regulation of cellular ketone metabolic process GO:0010565 66 0.682
dentate gyrus development GO:0021542 14 0.682
cerebellar cortex development GO:0021695 48 0.680
lung development GO:0030324 164 0.680
regulation of cerebellar granule cell precursor proliferation GO:0021936 12 0.679
positive regulation of chondrocyte differentiation GO:0032332 13 0.679
metanephric nephron morphogenesis GO:0072273 19 0.679
cell differentiation in spinal cord GO:0021515 53 0.675
ventricular septum morphogenesis GO:0060412 27 0.672
hematopoietic progenitor cell differentiation GO:0002244 143 0.672
regulation of neuroblast proliferation GO:1902692 27 0.668
lens induction in camera type eye GO:0060235 7 0.665
cardiac right atrium morphogenesis GO:0003213 3 0.664
auditory receptor cell fate specification GO:0042667 1 0.663
cerebral cortex development GO:0021987 86 0.663
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.662
cochlea morphogenesis GO:0090103 22 0.661
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 4 0.660
stem cell fate determination GO:0048867 2 0.658
negative regulation of molecular function GO:0044092 258 0.655
branching morphogenesis of an epithelial tube GO:0048754 159 0.654
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.653
exocrine system development GO:0035272 45 0.653
retina morphogenesis in camera type eye GO:0060042 45 0.652
negative regulation of stem cell maintenance GO:1902455 4 0.652
digestive system development GO:0055123 200 0.652
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.650
renal vesicle induction GO:0072034 3 0.650
negative regulation of cell fate specification GO:0009996 4 0.649
negative regulation of gastrulation GO:2000542 3 0.649
cerebellum formation GO:0021588 1 0.648
cranial nerve formation GO:0021603 4 0.644
ameboidal type cell migration GO:0001667 128 0.644
embryonic heart tube morphogenesis GO:0003143 51 0.643
ureteric bud morphogenesis GO:0060675 62 0.643
regulation of osteoblast differentiation GO:0045667 67 0.640
lung morphogenesis GO:0060425 50 0.640
regulation of smoothened signaling pathway GO:0008589 58 0.640
positive regulation of dna templated transcription elongation GO:0032786 2 0.639
neural nucleus development GO:0048857 22 0.638
endochondral bone morphogenesis GO:0060350 50 0.638
nephric duct formation GO:0072179 4 0.637
leukocyte differentiation GO:0002521 342 0.635
fat cell differentiation GO:0045444 160 0.630
negative regulation of endodermal cell differentiation GO:1903225 1 0.626
mesodermal cell differentiation GO:0048333 22 0.626
melanocyte differentiation GO:0030318 25 0.623
ureteric bud development GO:0001657 94 0.622
midgut development GO:0007494 4 0.621
diencephalon morphogenesis GO:0048852 6 0.621
regulation of neuron apoptotic process GO:0043523 122 0.620
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.619
nephrogenic mesenchyme development GO:0072076 3 0.618
ventral spinal cord interneuron specification GO:0021521 11 0.614
ectoderm formation GO:0001705 3 0.613
subpallium neuron fate commitment GO:0060163 2 0.609
metanephric renal vesicle morphogenesis GO:0072283 12 0.607
polarity specification of proximal distal axis GO:0010085 2 0.606
preganglionic parasympathetic nervous system development GO:0021783 17 0.603
regulation of cell cycle GO:0051726 281 0.602
autonomic nervous system development GO:0048483 43 0.602
commitment of multipotent stem cells to neuronal lineage in forebrain GO:0021898 3 0.601
bone development GO:0060348 120 0.601
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.598
urogenital system development GO:0001655 261 0.595
artery development GO:0060840 53 0.593
carbon catabolite activation of transcription GO:0045991 4 0.590
chondrocyte development GO:0002063 24 0.589
neuron apoptotic process GO:0051402 142 0.588
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 9 0.587
transforming growth factor beta receptor signaling pathway involved in primitive streak formation GO:0090010 1 0.584
regulation of retina development in camera type eye GO:1902866 3 0.578
single organism nuclear import GO:1902593 95 0.577
salivary gland morphogenesis GO:0007435 33 0.576
negative regulation of osteoblast differentiation GO:0045668 30 0.573
somite development GO:0061053 81 0.572
positive regulation of cartilage development GO:0061036 18 0.571
central nervous system neuron development GO:0021954 67 0.566
ventricular zone neuroblast division GO:0021847 3 0.564
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.563
regulation of cellular amine metabolic process GO:0033238 20 0.561
spinal cord patterning GO:0021511 25 0.560
branching involved in ureteric bud morphogenesis GO:0001658 56 0.559
mesenchymal cell differentiation involved in lung development GO:0060915 2 0.559
striated muscle tissue development GO:0014706 293 0.556
motor neuron migration GO:0097475 4 0.552
asymmetric neuroblast division GO:0055059 1 0.552
forebrain ventricular zone progenitor cell division GO:0021869 6 0.550
negative regulation of cell proliferation GO:0008285 296 0.549
spinal cord motor neuron migration GO:0097476 4 0.548
astrocyte fate commitment GO:0060018 4 0.547
negative regulation of astrocyte differentiation GO:0048712 10 0.546
axis elongation GO:0003401 30 0.543
magnesium ion homeostasis GO:0010960 6 0.541
metanephros morphogenesis GO:0003338 24 0.538
kidney morphogenesis GO:0060993 83 0.538
osteoblast development GO:0002076 17 0.538
negative regulation of transcription by glucose GO:0045014 1 0.537
pons development GO:0021548 13 0.533
negative regulation of neuron projection development GO:0010977 50 0.532
developmental maturation GO:0021700 193 0.531
mitral valve morphogenesis GO:0003183 4 0.530
regulation of kidney development GO:0090183 40 0.528
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 5 0.527
nephron morphogenesis GO:0072028 69 0.524
prostate gland stromal morphogenesis GO:0060741 2 0.524
neural crest cell development GO:0014032 48 0.523
positive regulation of organ growth GO:0046622 29 0.523
noradrenergic neuron differentiation GO:0003357 6 0.523
regulation of organ formation GO:0003156 34 0.519
neuroblast fate commitment GO:0014017 1 0.517
peripheral nervous system neuron axonogenesis GO:0048936 3 0.516
blood vessel morphogenesis GO:0048514 285 0.516
organ induction GO:0001759 21 0.516
spinal cord motor neuron differentiation GO:0021522 35 0.515
positive regulation of striated muscle tissue development GO:0045844 31 0.511
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.511
placenta development GO:0001890 140 0.511
negative regulation of neuron death GO:1901215 98 0.508
cell migration involved in gastrulation GO:0042074 13 0.506
embryonic skeletal joint development GO:0072498 13 0.506
embryonic placenta development GO:0001892 98 0.504
smoothened signaling pathway GO:0007224 105 0.504
hindbrain tangential cell migration GO:0021934 2 0.504
dendrite development GO:0016358 115 0.503
kidney mesenchyme morphogenesis GO:0072131 4 0.502
canonical wnt signaling pathway GO:0060070 130 0.501
kidney development GO:0001822 213 0.501
neuroblast division GO:0055057 10 0.501
ossification GO:0001503 216 0.501
regulation of cardiac muscle tissue growth GO:0055021 26 0.500
cardiac muscle cell differentiation GO:0055007 69 0.500
negative regulation of nervous system development GO:0051961 156 0.500
photoreceptor cell development GO:0042461 40 0.499
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 12 0.499
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.499
epithelial cell proliferation GO:0050673 174 0.499
genitalia morphogenesis GO:0035112 11 0.497
metanephric nephron tubule formation GO:0072289 4 0.497
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.496
morphogenesis of a polarized epithelium GO:0001738 37 0.495
axial mesodermal cell differentiation GO:0048321 1 0.493
negative regulation of kidney development GO:0090185 15 0.492
spinal cord association neuron differentiation GO:0021527 14 0.492
positive regulation of vascular wound healing GO:0035470 1 0.491
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.489
forebrain regionalization GO:0021871 25 0.486
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.485
central nervous system vasculogenesis GO:0022009 3 0.485
apoptotic process involved in patterning of blood vessels GO:1902262 6 0.482
noradrenergic neuron development GO:0003358 3 0.481
mesonephric tubule development GO:0072164 94 0.481
mechanoreceptor differentiation GO:0042490 67 0.480
cardiac chamber morphogenesis GO:0003206 93 0.478
middle ear morphogenesis GO:0042474 23 0.476
Mouse
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.475
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.475
positive regulation of cardiac muscle tissue development GO:0055025 19 0.474
positive regulation of neuron projection regeneration GO:0070572 2 0.472
mesenchymal to epithelial transition GO:0060231 12 0.471
establishment of neuroblast polarity GO:0045200 1 0.468
axonogenesis involved in innervation GO:0060385 5 0.465
regulation of astrocyte differentiation GO:0048710 20 0.464
spinal cord motor neuron cell fate specification GO:0021520 13 0.464
heart field specification GO:0003128 6 0.464
gliogenesis GO:0042063 141 0.463
Fly
bone morphogenesis GO:0060349 78 0.463
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.463
positive regulation of angiogenesis GO:0045766 46 0.462
sinoatrial node cell differentiation GO:0060921 3 0.460
positive regulation of epithelial to mesenchymal transition GO:0010718 13 0.458
dorsal ventral axon guidance GO:0033563 3 0.458
cellular response to growth factor stimulus GO:0071363 197 0.457
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.456
cell differentiation involved in kidney development GO:0061005 33 0.455
amacrine cell differentiation GO:0035881 5 0.448
lens development in camera type eye GO:0002088 62 0.446
cerebellum morphogenesis GO:0021587 42 0.446
chemotaxis GO:0006935 247 0.445
metanephric mesenchyme morphogenesis GO:0072133 4 0.444
endoderm formation GO:0001706 20 0.441
determination of heart left right asymmetry GO:0061371 48 0.441
negative regulation of creb transcription factor activity GO:0032792 2 0.440
negative regulation of chondrocyte differentiation GO:0032331 13 0.434
craniofacial suture morphogenesis GO:0097094 10 0.432
negative regulation of prostatic bud formation GO:0060686 4 0.432
peripheral nervous system neuron development GO:0048935 9 0.431
negative regulation of immature t cell proliferation GO:0033087 3 0.430
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.430
cell migration involved in mesendoderm migration GO:0090134 1 0.429
oogenesis GO:0048477 56 0.427
Worm
segmentation GO:0035282 93 0.423
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.423
alpha beta t cell differentiation GO:0046632 69 0.422
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 0.421
trigeminal nerve development GO:0021559 10 0.421
skeletal muscle cell differentiation GO:0035914 66 0.419
epithelial cell maturation GO:0002070 15 0.417
mesendoderm development GO:0048382 3 0.416
medulla oblongata development GO:0021550 3 0.408
vascular wound healing GO:0061042 3 0.407

Msx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.730
Human
disease of anatomical entity DOID:7 0 0.730
Human
musculoskeletal system disease DOID:17 0 0.730
Human
connective tissue disease DOID:65 0 0.730
Human
bone development disease DOID:0080006 0 0.602
Human