Mus musculus

58 known processes

Mtbp

Mdm2, transformed 3T3 cell double minute p53 binding protein

(Aliases: AI429604,MDM2BP)

Mtbp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear division GO:0000280 158 0.148
dna metabolic process GO:0006259 303 0.140
microtubule based process GO:0007017 236 0.123
organic cyclic compound catabolic process GO:1901361 295 0.117
cellular amino acid metabolic process GO:0006520 103 0.116
mitotic cell cycle process GO:1903047 159 0.106
organelle fission GO:0048285 170 0.105
cellular response to dna damage stimulus GO:0006974 207 0.098
meiotic nuclear division GO:0007126 115 0.093
negative regulation of cellular component organization GO:0051129 194 0.084
dna repair GO:0006281 107 0.084
microtubule cytoskeleton organization GO:0000226 157 0.078
cellular macromolecule catabolic process GO:0044265 206 0.073
regulation of cellular amino acid metabolic process GO:0006521 5 0.071
recombinational repair GO:0000725 21 0.067
cell cycle checkpoint GO:0000075 47 0.064
cellular ketone metabolic process GO:0042180 84 0.057
regulation of cellular amine metabolic process GO:0033238 20 0.056
organonitrogen compound catabolic process GO:1901565 264 0.056
nitrogen compound transport GO:0071705 271 0.055
dna recombination GO:0006310 92 0.055
double strand break repair via homologous recombination GO:0000724 21 0.051
cellular amine metabolic process GO:0044106 44 0.051
mitotic cell cycle GO:0000278 195 0.051
amine metabolic process GO:0009308 45 0.050
double strand break repair GO:0006302 48 0.050
nucleoside phosphate metabolic process GO:0006753 338 0.048
organophosphate catabolic process GO:0046434 232 0.047
cytoplasmic transport GO:0016482 234 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
glycosyl compound metabolic process GO:1901657 246 0.045
nucleoside triphosphate metabolic process GO:0009141 230 0.044
regulation of cell cycle GO:0051726 281 0.044
purine nucleotide catabolic process GO:0006195 211 0.043
meiotic cell cycle GO:0051321 122 0.043
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.043
chromosome segregation GO:0007059 48 0.042
response to radiation GO:0009314 165 0.042
nuclear transport GO:0051169 139 0.040
nucleotide metabolic process GO:0009117 332 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.039
chromatin organization GO:0006325 206 0.038
purine ribonucleotide catabolic process GO:0009154 208 0.037
nucleocytoplasmic transport GO:0006913 139 0.037
purine nucleoside triphosphate metabolic process GO:0009144 226 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
peptidyl amino acid modification GO:0018193 336 0.036
double strand break repair via nonhomologous end joining GO:0006303 10 0.035
glycosyl compound catabolic process GO:1901658 206 0.035
regulation of cell cycle process GO:0010564 160 0.034
carbohydrate derivative catabolic process GO:1901136 231 0.034
spermatid development GO:0007286 108 0.034
histone modification GO:0016570 159 0.034
male gamete generation GO:0048232 285 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
modification dependent macromolecule catabolic process GO:0043632 133 0.031
nucleoside monophosphate metabolic process GO:0009123 85 0.031
nucleoside metabolic process GO:0009116 246 0.030
spermatogenesis GO:0007283 284 0.030
purine nucleoside catabolic process GO:0006152 205 0.030
purine nucleotide metabolic process GO:0006163 302 0.030
synapsis GO:0007129 34 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.029
regulation of cell cycle g2 m phase transition GO:1902749 10 0.029
regulation of mitotic cell cycle GO:0007346 126 0.029
positive regulation of protein modification process GO:0031401 299 0.028
negative regulation of cell cycle GO:0045786 123 0.028
nucleotide catabolic process GO:0009166 217 0.028
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
b cell activation GO:0042113 161 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
regulation of membrane potential GO:0042391 192 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
regulation of microtubule based process GO:0032886 52 0.027
nuclear import GO:0051170 95 0.026
cellular response to organonitrogen compound GO:0071417 145 0.026
purine nucleoside triphosphate catabolic process GO:0009146 203 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.026
heterocycle catabolic process GO:0046700 280 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
negative regulation of organelle organization GO:0010639 90 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.025
positive regulation of lymphocyte activation GO:0051251 140 0.025
ribonucleoside metabolic process GO:0009119 245 0.025
aromatic compound catabolic process GO:0019439 286 0.025
protein methylation GO:0006479 81 0.025
chromosome organization involved in meiosis GO:0070192 39 0.024
protein import GO:0017038 101 0.024
purine containing compound catabolic process GO:0072523 213 0.024
regulation of cell cycle phase transition GO:1901987 77 0.024
macromolecule catabolic process GO:0009057 281 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
regulation of centriole replication GO:0046599 1 0.024
purine containing compound metabolic process GO:0072521 311 0.024
apoptotic signaling pathway GO:0097190 306 0.024
chromatin modification GO:0016568 187 0.024
ribonucleotide catabolic process GO:0009261 208 0.023
male meiosis GO:0007140 37 0.023
regulation of hydrolase activity GO:0051336 246 0.023
lipid biosynthetic process GO:0008610 179 0.023
folic acid containing compound metabolic process GO:0006760 3 0.023
meiotic cell cycle process GO:1903046 77 0.023
developmental maturation GO:0021700 193 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
regulation of chromosome organization GO:0033044 83 0.023
dna catabolic process endonucleolytic GO:0000737 15 0.022
regulation of histone modification GO:0031056 56 0.022
nuclear export GO:0051168 34 0.022
leukocyte differentiation GO:0002521 342 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
female meiosis chromosome segregation GO:0016321 1 0.021
maintenance of location GO:0051235 89 0.021
protein targeting GO:0006605 143 0.021
intracellular protein transport GO:0006886 204 0.021
regulation of cell activation GO:0050865 289 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
camera type eye development GO:0043010 266 0.021
ras protein signal transduction GO:0007265 77 0.021
regulation of transferase activity GO:0051338 263 0.021
lymphocyte differentiation GO:0030098 242 0.021
organelle assembly GO:0070925 177 0.020
atp catabolic process GO:0006200 55 0.020
mrna transport GO:0051028 13 0.020
germ cell development GO:0007281 185 0.020
adaptive immune response GO:0002250 155 0.020
positive regulation of cell activation GO:0050867 158 0.020
t cell activation GO:0042110 289 0.020
regulation of cellular component biogenesis GO:0044087 181 0.020
cation transport GO:0006812 399 0.020
response to light stimulus GO:0009416 135 0.019
pore complex assembly GO:0046931 3 0.019
nucleoside catabolic process GO:0009164 206 0.019
negative regulation of cell cycle phase transition GO:1901988 48 0.019
protein localization to nucleus GO:0034504 121 0.019
single organism nuclear import GO:1902593 95 0.019
covalent chromatin modification GO:0016569 163 0.019
male meiosis i GO:0007141 16 0.019
membrane organization GO:0061024 245 0.019
establishment of protein localization to organelle GO:0072594 118 0.019
multicellular organismal signaling GO:0035637 91 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
positive regulation of nervous system development GO:0051962 221 0.019
protein maturation GO:0051604 176 0.018
leukocyte mediated immunity GO:0002443 174 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
negative regulation of dna replication GO:0008156 4 0.018
anion transport GO:0006820 177 0.018
gland development GO:0048732 330 0.018
organelle localization GO:0051640 179 0.018
methylation GO:0032259 134 0.018
establishment or maintenance of cell polarity GO:0007163 86 0.018
response to organonitrogen compound GO:0010243 246 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.017
fertilization GO:0009566 127 0.017
histone lysine methylation GO:0034968 50 0.017
nucleus organization GO:0006997 45 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
cell activation involved in immune response GO:0002263 126 0.017
protein import into nucleus GO:0006606 95 0.017
regulation of kinase activity GO:0043549 249 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
meiosis i GO:0007127 60 0.017
atp metabolic process GO:0046034 75 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
skeletal system development GO:0001501 356 0.017
regulation of secretion by cell GO:1903530 249 0.017
protein catabolic process GO:0030163 221 0.017
tube formation GO:0035148 140 0.017
regulation of cellular response to stress GO:0080135 159 0.017
mitotic nuclear division GO:0007067 48 0.017
intra s dna damage checkpoint GO:0031573 4 0.017
action potential GO:0001508 78 0.017
anatomical structure homeostasis GO:0060249 145 0.017
ion transmembrane transport GO:0034220 361 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
regulation of protein localization GO:0032880 231 0.016
immune effector process GO:0002252 321 0.016
establishment of organelle localization GO:0051656 122 0.016
rna localization GO:0006403 23 0.016
mapk cascade GO:0000165 281 0.016
nucleobase containing compound transport GO:0015931 27 0.016
regulation of organelle organization GO:0033043 289 0.016
peptidyl serine modification GO:0018209 83 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.016
microtubule organizing center organization GO:0031023 28 0.016
macromolecule methylation GO:0043414 120 0.016
protein localization to organelle GO:0033365 185 0.015
regulation of t cell activation GO:0050863 170 0.015
development of primary sexual characteristics GO:0045137 143 0.015
transmembrane transport GO:0055085 412 0.015
response to uv GO:0009411 44 0.015
smoothened signaling pathway GO:0007224 105 0.015
antimicrobial peptide production GO:0002775 2 0.015
retina development in camera type eye GO:0060041 119 0.015
histone threonine phosphorylation GO:0035405 1 0.015
regulation of nuclear division GO:0051783 56 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
peptidyl lysine modification GO:0018205 77 0.015
regulation of secretion GO:0051046 274 0.014
endomembrane system organization GO:0010256 147 0.014
actin filament based movement GO:0030048 23 0.014
protein alkylation GO:0008213 81 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
inflammatory response GO:0006954 244 0.014
dna integrity checkpoint GO:0031570 28 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
protein ubiquitination GO:0016567 171 0.014
regulation of protein maturation GO:1903317 96 0.014
sister chromatid segregation GO:0000819 20 0.014
cofactor metabolic process GO:0051186 80 0.014
dna catabolic process GO:0006308 19 0.014
negative regulation of cell cycle process GO:0010948 69 0.014
spermatid differentiation GO:0048515 115 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
negative regulation of dna recombination GO:0045910 13 0.014
sensory organ morphogenesis GO:0090596 242 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
regulation of neuron differentiation GO:0045664 281 0.013
cell growth GO:0016049 130 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
centrosome cycle GO:0007098 23 0.013
intracellular mrna localization GO:0008298 4 0.013
leukocyte proliferation GO:0070661 172 0.013
regulation of intracellular transport GO:0032386 159 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
heterochromatin organization GO:0070828 4 0.013
purine nucleoside monophosphate catabolic process GO:0009128 58 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
regulation of mitotic cell cycle phase transition GO:1901990 73 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
lymphocyte proliferation GO:0046651 164 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
establishment of rna localization GO:0051236 18 0.013
centriole assembly GO:0098534 6 0.013
homeostasis of number of cells GO:0048872 210 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
regulation of leukocyte proliferation GO:0070663 121 0.013
cellular response to lipid GO:0071396 145 0.013
muscle cell differentiation GO:0042692 261 0.012
cell maturation GO:0048469 127 0.012
coenzyme metabolic process GO:0006732 52 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
regulation of mapk cascade GO:0043408 248 0.012
dna damage checkpoint GO:0000077 26 0.012
blastocyst development GO:0001824 80 0.012
attachment of spindle microtubules to kinetochore GO:0008608 4 0.012
blood vessel morphogenesis GO:0048514 285 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
negative regulation of protein processing GO:0010955 79 0.012
epithelial tube formation GO:0072175 130 0.012
neural tube formation GO:0001841 108 0.012
synaptonemal complex organization GO:0070193 15 0.012
cilium assembly GO:0042384 81 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
organic anion transport GO:0015711 137 0.012
regulation of cell division GO:0051302 76 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
regulation of microtubule cytoskeleton organization GO:0070507 37 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
alpha amino acid metabolic process GO:1901605 59 0.012
regulation of cell migration GO:0030334 219 0.012
telomere capping GO:0016233 4 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
histone h3 k9 methylation GO:0051567 17 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
regulation of dna recombination GO:0000018 34 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
cellular protein complex assembly GO:0043623 116 0.011
cytokine production GO:0001816 319 0.011
mitotic cell cycle checkpoint GO:0007093 31 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
regulation of protein catabolic process GO:0042176 108 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
sensory perception GO:0007600 245 0.011
regulation of system process GO:0044057 200 0.011
nucleic acid transport GO:0050657 18 0.011
response to acid chemical GO:0001101 111 0.011
positive regulation of cell death GO:0010942 224 0.011
oxidation reduction process GO:0055114 342 0.011
response to growth factor GO:0070848 198 0.011
cellular lipid metabolic process GO:0044255 323 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.011
negative regulation of protein modification process GO:0031400 163 0.011
b cell mediated immunity GO:0019724 71 0.011
regulation of histone h3 k36 methylation GO:0000414 1 0.011
dna replication GO:0006260 52 0.011
negative regulation of cell development GO:0010721 169 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
positive regulation of organelle organization GO:0010638 128 0.011
regulation of cytokine production GO:0001817 266 0.011
divalent metal ion transport GO:0070838 172 0.011
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
positive regulation of lymphocyte proliferation GO:0050671 70 0.011
protein oligomerization GO:0051259 67 0.011
cation transmembrane transport GO:0098655 266 0.011
tube closure GO:0060606 91 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
b cell differentiation GO:0030183 78 0.010
lipid localization GO:0010876 126 0.010
regulation of hormone levels GO:0010817 211 0.010
small molecule biosynthetic process GO:0044283 132 0.010
response to lipopolysaccharide GO:0032496 128 0.010
neural tube development GO:0021915 160 0.010
histone methylation GO:0016571 71 0.010
positive regulation of cell development GO:0010720 237 0.010
positive regulation of leukocyte proliferation GO:0070665 73 0.010
rna transport GO:0050658 18 0.010
connective tissue development GO:0061448 179 0.010
regulation of homeostatic process GO:0032844 182 0.010
urogenital system development GO:0001655 261 0.010
response to inorganic substance GO:0010035 96 0.010
compound eye development GO:0048749 1 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
regulation of cell projection organization GO:0031344 206 0.010
response to organic cyclic compound GO:0014070 198 0.010
regulation of chromatin modification GO:1903308 57 0.010

Mtbp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.091
cancer DOID:162 0 0.091
disease of anatomical entity DOID:7 0 0.044
hematopoietic system disease DOID:74 0 0.044
immune system disease DOID:2914 0 0.044
nervous system disease DOID:863 0 0.027
organ system cancer DOID:0050686 0 0.015
eye disease DOID:5614 0 0.014
eye and adnexa disease DOID:1492 0 0.014
sensory system disease DOID:0050155 0 0.014
retinal disease DOID:5679 0 0.014
retinal degeneration DOID:8466 0 0.013
anemia DOID:2355 0 0.013
bone marrow disease DOID:4961 0 0.013
aplastic anemia DOID:12449 0 0.013
physical disorder DOID:0080015 0 0.013
immune system cancer DOID:0060083 0 0.012
hematologic cancer DOID:2531 0 0.012
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010