Mus musculus

159 known processes

Mtf2

metal response element binding transcription factor 2

(Aliases: MGC116639,AA537621,9230112N11Rik,C76717,M96,Pcl2)

Mtf2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone h3 k9 methylation GO:0051567 17 0.999
histone methylation GO:0016571 71 0.991
positive regulation of histone h3 k9 methylation GO:0051574 4 0.991
histone lysine methylation GO:0034968 50 0.979
methylation GO:0032259 134 0.942
macromolecule methylation GO:0043414 120 0.934
histone h3 k27 methylation GO:0070734 11 0.923
regulation of histone h3 k9 methylation GO:0051570 8 0.921
dna modification GO:0006304 50 0.919
protein methylation GO:0006479 81 0.904
germ line stem cell division GO:0042078 2 0.885
protein alkylation GO:0008213 81 0.864
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.758
negative regulation of histone methylation GO:0031061 10 0.699
nucleosome positioning GO:0016584 4 0.655
regulation of histone methylation GO:0031060 30 0.590
rhythmic process GO:0048511 174 0.562
peptidyl lysine methylation GO:0018022 29 0.545
dna metabolic process GO:0006259 303 0.540
maintenance of cell number GO:0098727 3 0.494
cell division GO:0051301 120 0.426
regulation of synapse structural plasticity GO:0051823 4 0.365
regulation of chromosome organization GO:0033044 83 0.363
transcription elongation from rna polymerase ii promoter GO:0006368 9 0.354
positive regulation of histone methylation GO:0031062 16 0.347
chromatin modification GO:0016568 187 0.345
gene silencing by rna GO:0031047 19 0.320
muscle system process GO:0003012 141 0.311
positive regulation of organelle organization GO:0010638 128 0.308
protein acylation GO:0043543 64 0.292
regulation of chromatin modification GO:1903308 57 0.281
circadian rhythm GO:0007623 114 0.272
covalent chromatin modification GO:0016569 163 0.245
nuclear envelope organization GO:0006998 11 0.214
peptidyl lysine modification GO:0018205 77 0.208
positive regulation of histone h3 k27 methylation GO:0061087 4 0.206
dna methylation GO:0006306 43 0.205
establishment or maintenance of actin cytoskeleton polarity GO:0030950 1 0.203
dendrite development GO:0016358 115 0.200
regeneration GO:0031099 38 0.195
dendrite self avoidance GO:0070593 2 0.193
histone modification GO:0016570 159 0.180
mitotic cell cycle GO:0000278 195 0.176
negative regulation of cellular component organization GO:0051129 194 0.167
positive regulation of chromosome organization GO:2001252 33 0.167
regulation of striated muscle contraction GO:0006942 25 0.151
negative regulation of cellular protein metabolic process GO:0032269 247 0.150
muscle cell differentiation GO:0042692 261 0.147
viral process GO:0016032 41 0.146
chromatin organization GO:0006325 206 0.142
cellular response to oxidative stress GO:0034599 76 0.141
synaptic transmission GO:0007268 329 0.139
response to lipopolysaccharide GO:0032496 128 0.138
termination of rna polymerase ii transcription GO:0006369 1 0.137
axon guidance GO:0007411 141 0.136
protein localization to organelle GO:0033365 185 0.136
negative regulation of transcription elongation from rna polymerase ii promoter GO:0034244 6 0.136
regulation of histone h3 k27 methylation GO:0061085 6 0.136
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.134
negative regulation of protein modification process GO:0031400 163 0.132
regulation of chromatin organization GO:1902275 57 0.130
regulation of skeletal muscle contraction GO:0014819 3 0.128
dna templated transcription termination GO:0006353 4 0.128
regulation of cell cycle g1 s phase transition GO:1902806 35 0.126
muscle contraction GO:0006936 101 0.125
mitotic cell cycle process GO:1903047 159 0.118
negative regulation of chromosome organization GO:2001251 30 0.117
telomere maintenance GO:0000723 19 0.113
regulation of blood circulation GO:1903522 93 0.111
negative regulation of protein metabolic process GO:0051248 282 0.111
regulation of retinoic acid receptor signaling pathway GO:0048385 7 0.110
peptidyl amino acid modification GO:0018193 336 0.108
response to hydrogen peroxide GO:0042542 32 0.108
regulation of muscle system process GO:0090257 80 0.103
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.095
negative regulation of chromatin modification GO:1903309 19 0.095
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.093
axonogenesis GO:0007409 274 0.092
cell cycle comprising mitosis without cytokinesis GO:0033301 1 0.091
skeletal muscle tissue regeneration GO:0043403 20 0.085
cell cycle g1 s phase transition GO:0044843 57 0.083
negative regulation of striated muscle cell differentiation GO:0051154 14 0.081
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.080
rna interference GO:0016246 2 0.080
regulation of cellular amino acid metabolic process GO:0006521 5 0.079
negative regulation of kinase activity GO:0033673 81 0.079
positive regulation of histone h3 k4 methylation GO:0051571 5 0.078
regulation of cellular ketone metabolic process GO:0010565 66 0.077
regulation of transferase activity GO:0051338 263 0.077
dna alkylation GO:0006305 43 0.076
telomere maintenance in response to dna damage GO:0043247 4 0.076
chromatin assembly GO:0031497 13 0.075
regulation of mrna splicing via spliceosome GO:0048024 32 0.073
nucleoside triphosphate metabolic process GO:0009141 230 0.073
cellular chemical homeostasis GO:0055082 215 0.070
regulation of cellular component biogenesis GO:0044087 181 0.070
spleen development GO:0048536 39 0.067
calcium mediated signaling GO:0019722 46 0.065
purine ribonucleotide catabolic process GO:0009154 208 0.064
dna hypermethylation GO:0044026 3 0.064
meiotic cell cycle GO:0051321 122 0.062
nucleoside monophosphate metabolic process GO:0009123 85 0.062
heterocycle catabolic process GO:0046700 280 0.062
protection from non homologous end joining at telomere GO:0031848 4 0.061
mrna transport GO:0051028 13 0.058
cellular response to dna damage stimulus GO:0006974 207 0.058
positive regulation of apoptotic process GO:0043065 217 0.057
positive regulation of chromatin modification GO:1903310 28 0.057
hindbrain development GO:0030902 128 0.057
regulation of histone modification GO:0031056 56 0.057
negative regulation of molecular function GO:0044092 258 0.054
mapk cascade GO:0000165 281 0.053
membrane depolarization GO:0051899 64 0.053
membrane organization GO:0061024 245 0.053
cellular metal ion homeostasis GO:0006875 151 0.052
negative regulation of histone h3 k9 methylation GO:0051573 4 0.052
regulation of neuron differentiation GO:0045664 281 0.051
negative regulation of map kinase activity GO:0043407 34 0.051
negative regulation of organelle organization GO:0010639 90 0.050
posttranscriptional regulation of gene expression GO:0010608 155 0.050
organelle assembly GO:0070925 177 0.050
cellular amino acid metabolic process GO:0006520 103 0.049
aromatic compound catabolic process GO:0019439 286 0.049
positive regulation of programmed cell death GO:0043068 218 0.049
cellular amine metabolic process GO:0044106 44 0.049
cellular response to organonitrogen compound GO:0071417 145 0.048
cellular homeostasis GO:0019725 240 0.048
positive regulation of cellular amine metabolic process GO:0033240 5 0.048
divalent inorganic cation homeostasis GO:0072507 138 0.047
regulation of postsynaptic membrane potential GO:0060078 48 0.046
regulation of mapk cascade GO:0043408 248 0.046
positive regulation of protein modification process GO:0031401 299 0.044
cellular divalent inorganic cation homeostasis GO:0072503 127 0.044
gliogenesis GO:0042063 141 0.044
translation GO:0006412 93 0.042
positive regulation of histone modification GO:0031058 28 0.042
rna splicing GO:0008380 54 0.042
g1 s transition of mitotic cell cycle GO:0000082 57 0.040
purine ribonucleoside catabolic process GO:0046130 205 0.040
cytokinetic process GO:0032506 2 0.040
negative regulation of phosphate metabolic process GO:0045936 184 0.040
cation transport GO:0006812 399 0.040
chromatin silencing GO:0006342 15 0.038
protein localization to chromatin GO:0071168 3 0.038
chromosome organization involved in meiosis GO:0070192 39 0.037
genetic imprinting GO:0071514 27 0.037
negative regulation of cell cycle GO:0045786 123 0.036
cellular ketone metabolic process GO:0042180 84 0.036
stem cell division GO:0017145 30 0.035
negative regulation of dna templated transcription elongation GO:0032785 6 0.035
ribose phosphate metabolic process GO:0019693 291 0.034
dna integrity checkpoint GO:0031570 28 0.034
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.033
negative regulation of cell cycle g1 s phase transition GO:1902807 18 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.033
cation homeostasis GO:0055080 212 0.033
regulation of striated muscle cell differentiation GO:0051153 81 0.033
glycosyl compound catabolic process GO:1901658 206 0.032
microtubule based process GO:0007017 236 0.032
negative regulation of epidermal cell differentiation GO:0045605 7 0.032
myotube differentiation GO:0014902 105 0.031
nucleoside triphosphate catabolic process GO:0009143 205 0.031
maintenance of protein location in nucleus GO:0051457 2 0.031
regulation of cell cycle process GO:0010564 160 0.031
calcium ion homeostasis GO:0055074 127 0.031
negative regulation of cell proliferation GO:0008285 296 0.031
heterochromatin organization GO:0070828 4 0.031
regulation of skeletal muscle contraction by calcium ion signaling GO:0014722 3 0.031
regulation of cell cycle phase transition GO:1901987 77 0.031
interspecies interaction between organisms GO:0044419 83 0.030
stem cell differentiation GO:0048863 268 0.030
atp metabolic process GO:0046034 75 0.030
dna replication GO:0006260 52 0.030
regulation of system process GO:0044057 200 0.030
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.029
protein localization to chromosome GO:0034502 6 0.029
apoptotic signaling pathway GO:0097190 306 0.029
cellular calcium ion homeostasis GO:0006874 119 0.029
purine containing compound catabolic process GO:0072523 213 0.029
nuclear dna replication GO:0033260 3 0.029
compound eye development GO:0048749 1 0.029
telomere capping GO:0016233 4 0.028
metencephalon development GO:0022037 89 0.028
regulation of protein maturation GO:1903317 96 0.028
negative regulation of mitotic cell cycle GO:0045930 58 0.027
locomotory behavior GO:0007626 195 0.027
protein dna complex subunit organization GO:0071824 28 0.027
organic cyclic compound catabolic process GO:1901361 295 0.027
protein processing GO:0016485 163 0.026
regulation of membrane potential GO:0042391 192 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.025
nucleoside metabolic process GO:0009116 246 0.025
ribonucleoside metabolic process GO:0009119 245 0.025
regulation of cell cycle GO:0051726 281 0.025
regulation of protein serine threonine kinase activity GO:0071900 157 0.025
posttranscriptional gene silencing GO:0016441 10 0.025
actin cytoskeleton organization GO:0030036 220 0.024
regulation of rna splicing GO:0043484 37 0.024
innate immune response GO:0045087 157 0.024
endomembrane system organization GO:0010256 147 0.024
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 9 0.024
purine nucleoside catabolic process GO:0006152 205 0.024
negative regulation of epidermis development GO:0045683 9 0.023
regulation of cellular catabolic process GO:0031329 242 0.023
spermatogenesis GO:0007283 284 0.022
meiotic nuclear division GO:0007126 115 0.022
dna catabolic process exonucleolytic GO:0000738 3 0.022
ribonucleoprotein complex subunit organization GO:0071826 28 0.022
negative regulation of dna replication GO:0008156 4 0.022
regulation of neuron projection development GO:0010975 169 0.022
macromolecule deacylation GO:0098732 37 0.022
cell recognition GO:0008037 83 0.022
purine containing compound metabolic process GO:0072521 311 0.021
leukocyte differentiation GO:0002521 342 0.021
regulation of multi organism process GO:0043900 111 0.021
regulation of homeostatic process GO:0032844 182 0.020
ras protein signal transduction GO:0007265 77 0.020
viral life cycle GO:0019058 36 0.020
positive regulation of cellular component biogenesis GO:0044089 94 0.020
cellular ion homeostasis GO:0006873 165 0.020
liver development GO:0001889 66 0.019
negative regulation of cell cycle phase transition GO:1901988 48 0.019
regulation of muscle contraction GO:0006937 49 0.019
mitotic chromosome condensation GO:0007076 1 0.019
ribonucleoprotein complex localization GO:0071166 1 0.019
hepaticobiliary system development GO:0061008 67 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
myeloid cell differentiation GO:0030099 233 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
protein polymerization GO:0051258 57 0.019
skeletal system development GO:0001501 356 0.018
regulation of mrna processing GO:0050684 41 0.018
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.018
nucleotide catabolic process GO:0009166 217 0.018
mrna processing GO:0006397 63 0.017
negative regulation of proteolysis GO:0045861 74 0.017
regulation of dna templated transcription elongation GO:0032784 10 0.017
regulation of metal ion transport GO:0010959 106 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.017
amine metabolic process GO:0009308 45 0.017
embryonic digestive tract development GO:0048566 27 0.017
regulation of dna replication GO:0006275 17 0.017
regulation of mitotic cell cycle GO:0007346 126 0.017
homeostasis of number of cells GO:0048872 210 0.016
metal ion homeostasis GO:0055065 189 0.016
dna packaging GO:0006323 30 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
organophosphate catabolic process GO:0046434 232 0.016
regulation of translation GO:0006417 71 0.016
histone h3 k9 acetylation GO:0043970 5 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.016
viral transcription GO:0019083 3 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
regulation of map kinase activity GO:0043405 120 0.016
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
nucleus organization GO:0006997 45 0.015
mitotic sister chromatid segregation GO:0000070 14 0.015
anatomical structure homeostasis GO:0060249 145 0.015
meiotic chromosome segregation GO:0045132 19 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
circadian regulation of gene expression GO:0032922 48 0.015
regulation of cell projection organization GO:0031344 206 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
regulation of gliogenesis GO:0014013 50 0.015
cell cycle checkpoint GO:0000075 47 0.015
pole plasm assembly GO:0007315 2 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 8 0.015
female gamete generation GO:0007292 74 0.014
regulation of mitotic cell cycle phase transition GO:1901990 73 0.014
atp catabolic process GO:0006200 55 0.014
rna splicing via transesterification reactions GO:0000375 43 0.014
response to extracellular stimulus GO:0009991 127 0.014
heart process GO:0003015 94 0.014
regulation of circadian rhythm GO:0042752 58 0.014
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.014
nucleotide metabolic process GO:0009117 332 0.014
negative regulation of viral process GO:0048525 23 0.014
purine nucleoside monophosphate catabolic process GO:0009128 58 0.014
microtubule polymerization or depolymerization GO:0031109 26 0.014
meiotic cell cycle process GO:1903046 77 0.014
response to estrogen GO:0043627 24 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
ossification GO:0001503 216 0.013
regulation of histone h3 k4 methylation GO:0051569 12 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.013
gland development GO:0048732 330 0.013
protein maturation GO:0051604 176 0.013
regulation of organelle organization GO:0033043 289 0.013
response to amino acid GO:0043200 37 0.013
male meiosis GO:0007140 37 0.013
positive regulation of dna templated transcription elongation GO:0032786 2 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
intracellular mrna localization GO:0008298 4 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
digestive tract morphogenesis GO:0048546 147 0.012
response to inorganic substance GO:0010035 96 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
striated muscle cell development GO:0055002 125 0.012
endonucleolytic cleavage of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000479 1 0.012
histone mrna metabolic process GO:0008334 3 0.012
regulation of cytokine production GO:0001817 266 0.012
alternative mrna splicing via spliceosome GO:0000380 12 0.012
regulation of meiotic cell cycle GO:0051445 34 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
regulation of transcription by chromatin organization GO:0034401 0 0.012
peptidyl serine phosphorylation GO:0018105 74 0.012
synapse organization GO:0050808 125 0.012
germ cell development GO:0007281 185 0.012
response to organonitrogen compound GO:0010243 246 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
regulation of myotube differentiation GO:0010830 62 0.011
cellular response to lipid GO:0071396 145 0.011
circulatory system process GO:0003013 197 0.011
establishment or maintenance of cell polarity GO:0007163 86 0.011
nucleoside catabolic process GO:0009164 206 0.011
chromosome segregation GO:0007059 48 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
negative regulation of nuclear division GO:0051784 19 0.011
coenzyme metabolic process GO:0006732 52 0.011
rna polyadenylation GO:0043631 6 0.011
nuclear transport GO:0051169 139 0.011
multicellular organismal aging GO:0010259 24 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
positive regulation of nervous system development GO:0051962 221 0.011
rna processing GO:0006396 105 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.010
positive regulation of cell cycle process GO:0090068 61 0.010
cerebellar cortex development GO:0021695 48 0.010
nucleoside phosphate catabolic process GO:1901292 222 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
cardiac muscle tissue development GO:0048738 130 0.010
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 18 0.010
nucleobase containing small molecule metabolic process GO:0055086 352 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.010
glycosyl compound metabolic process GO:1901657 246 0.010

Mtf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.055
disease of anatomical entity DOID:7 0 0.055
central nervous system disease DOID:331 0 0.021
amyotrophic lateral sclerosis DOID:332 0 0.015
motor neuron disease DOID:231 0 0.015
neurodegenerative disease DOID:1289 0 0.015