Mus musculus

0 known processes

Mvd

mevalonate (diphospho) decarboxylase

(Aliases: C78718,Mpd)

Mvd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sterol metabolic process GO:0016125 58 0.999
cellular alcohol metabolic process GO:0044107 3 0.985
sterol biosynthetic process GO:0016126 17 0.984
cellular alcohol biosynthetic process GO:0044108 3 0.980
cholesterol biosynthetic process GO:0006695 15 0.959
cholesterol metabolic process GO:0008203 56 0.952
alcohol biosynthetic process GO:0046165 43 0.920
steroid metabolic process GO:0008202 119 0.910
lipid biosynthetic process GO:0008610 179 0.908
Human
organic hydroxy compound metabolic process GO:1901615 203 0.900
alcohol metabolic process GO:0006066 116 0.876
organic hydroxy compound biosynthetic process GO:1901617 77 0.693
cellular lipid metabolic process GO:0044255 323 0.498
Human
steroid biosynthetic process GO:0006694 47 0.444
isoprenoid biosynthetic process GO:0008299 9 0.307
Human
small molecule biosynthetic process GO:0044283 132 0.306
liver development GO:0001889 66 0.210
response to oleic acid GO:0034201 1 0.203
regulation of cellular ketone metabolic process GO:0010565 66 0.195
thioester biosynthetic process GO:0035384 7 0.190
acyl coa biosynthetic process GO:0071616 7 0.163
cellular ketone metabolic process GO:0042180 84 0.158
response to nutrient levels GO:0031667 109 0.152
cellular amino acid metabolic process GO:0006520 103 0.147
cellular response to testosterone stimulus GO:0071394 1 0.132
triglyceride biosynthetic process GO:0019432 17 0.116
response to testosterone GO:0033574 3 0.115
ketone body metabolic process GO:1902224 3 0.100
coenzyme biosynthetic process GO:0009108 23 0.097
oxidation reduction process GO:0055114 342 0.097
nitrogen compound transport GO:0071705 271 0.095
compound eye development GO:0048749 1 0.094
response to starvation GO:0042594 65 0.088
response to organonitrogen compound GO:0010243 246 0.087
regulation of cellular amine metabolic process GO:0033238 20 0.086
regulation of lipid metabolic process GO:0019216 118 0.083
sulfur compound metabolic process GO:0006790 100 0.082
acyl coa metabolic process GO:0006637 19 0.082
regulation of organelle organization GO:0033043 289 0.081
gland development GO:0048732 330 0.080
regulation of secretion by cell GO:1903530 249 0.077
regulation of secretion GO:0051046 274 0.075
lipid transport GO:0006869 98 0.074
cellular amine metabolic process GO:0044106 44 0.073
peptide secretion GO:0002790 114 0.068
cellular response to lipid GO:0071396 145 0.068
positive regulation of protein modification process GO:0031401 299 0.066
amine metabolic process GO:0009308 45 0.063
response to sterol GO:0036314 4 0.061
regulation of phosphatidylcholine catabolic process GO:0010899 2 0.060
response to acid chemical GO:0001101 111 0.059
regulation of cellular amino acid metabolic process GO:0006521 5 0.058
negative regulation of molecular function GO:0044092 258 0.058
skin development GO:0043588 220 0.056
regulation of peptide transport GO:0090087 91 0.056
cellular response to hormone stimulus GO:0032870 150 0.056
organic acid transport GO:0015849 101 0.056
peptide transport GO:0015833 133 0.052
respiratory tube development GO:0030323 167 0.051
covalent chromatin modification GO:0016569 163 0.051
regulation of hormone levels GO:0010817 211 0.050
response to extracellular stimulus GO:0009991 127 0.050
hepaticobiliary system development GO:0061008 67 0.048
regulation of phospholipid catabolic process GO:0060696 2 0.047
positive regulation of cellular amine metabolic process GO:0033240 5 0.047
neutral lipid metabolic process GO:0006638 57 0.046
sterol transmembrane transport GO:0035382 2 0.045
thioester metabolic process GO:0035383 19 0.044
response to monosaccharide GO:0034284 67 0.043
hormone secretion GO:0046879 128 0.043
lipid localization GO:0010876 126 0.043
epidermis development GO:0008544 187 0.043
organic anion transport GO:0015711 137 0.042
synaptic transmission GO:0007268 329 0.042
peptide hormone secretion GO:0030072 109 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
negative regulation of protein metabolic process GO:0051248 282 0.040
response to peptide GO:1901652 136 0.039
sterol homeostasis GO:0055092 45 0.039
peptidyl amino acid modification GO:0018193 336 0.039
ion transmembrane transport GO:0034220 361 0.039
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.038
regulation of cholesterol metabolic process GO:0090181 14 0.038
cholesterol homeostasis GO:0042632 44 0.037
glucose homeostasis GO:0042593 128 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
positive regulation of steroid biosynthetic process GO:0010893 4 0.036
amide transport GO:0042886 138 0.036
cellular response to nutrient levels GO:0031669 64 0.036
lung development GO:0030324 164 0.036
organic hydroxy compound transport GO:0015850 93 0.035
glycerolipid metabolic process GO:0046486 122 0.035
positive regulation of protein phosphorylation GO:0001934 242 0.034
cholesterol import GO:0070508 2 0.034
cofactor metabolic process GO:0051186 80 0.033
regulation of protein kinase activity GO:0045859 232 0.033
regulation of cell cycle GO:0051726 281 0.032
carboxylic acid transport GO:0046942 100 0.031
response to fatty acid GO:0070542 8 0.031
protein catabolic process GO:0030163 221 0.031
sulfur compound biosynthetic process GO:0044272 37 0.031
regulation of homeostatic process GO:0032844 182 0.031
protein processing GO:0016485 163 0.031
anion transport GO:0006820 177 0.030
regulation of defense response GO:0031347 233 0.030
response to cholesterol GO:0070723 4 0.030
positive regulation of transferase activity GO:0051347 167 0.030
fatty acid elongation GO:0030497 3 0.029
regulation of response to wounding GO:1903034 189 0.029
membrane lipid metabolic process GO:0006643 53 0.029
cellular response to external stimulus GO:0071496 88 0.028
regulation of peptide secretion GO:0002791 77 0.028
positive regulation of secretion GO:0051047 130 0.028
isoprenoid metabolic process GO:0006720 29 0.028
Human
response to peptide hormone GO:0043434 127 0.028
membrane organization GO:0061024 245 0.028
cellular chemical homeostasis GO:0055082 215 0.027
amino acid transport GO:0006865 61 0.026
insulin secretion GO:0030073 89 0.026
skeletal muscle organ development GO:0060538 163 0.026
male gamete generation GO:0048232 285 0.026
regulation of cellular response to stress GO:0080135 159 0.026
placenta blood vessel development GO:0060674 31 0.026
fat cell differentiation GO:0045444 160 0.026
sterol transport GO:0015918 38 0.025
positive regulation of secretion by cell GO:1903532 114 0.025
positive regulation of nervous system development GO:0051962 221 0.025
regulation of kinase activity GO:0043549 249 0.025
transmembrane transport GO:0055085 412 0.024
maintenance of location GO:0051235 89 0.024
cellular response to acid chemical GO:0071229 68 0.024
carbohydrate homeostasis GO:0033500 128 0.024
anion transmembrane transport GO:0098656 71 0.024
negative regulation of defense response GO:0031348 77 0.024
smoothened signaling pathway GO:0007224 105 0.024
regulation of transferase activity GO:0051338 263 0.023
lateral inhibition GO:0046331 1 0.023
telencephalon development GO:0021537 186 0.023
positive regulation of organelle organization GO:0010638 128 0.023
regulation of cell activation GO:0050865 289 0.023
ras protein signal transduction GO:0007265 77 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
response to organic cyclic compound GO:0014070 198 0.023
positive regulation of cholesterol storage GO:0010886 3 0.023
cellular homeostasis GO:0019725 240 0.023
protein maturation GO:0051604 176 0.023
regulation of protein serine threonine kinase activity GO:0071900 157 0.022
inflammatory response GO:0006954 244 0.022
lipid homeostasis GO:0055088 63 0.022
positive regulation of triglyceride metabolic process GO:0090208 9 0.022
peptidyl tyrosine phosphorylation GO:0018108 143 0.022
regulation of peptide hormone secretion GO:0090276 75 0.021
adipose tissue development GO:0060612 25 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
histone modification GO:0016570 159 0.021
rho protein signal transduction GO:0007266 32 0.021
labyrinthine layer blood vessel development GO:0060716 21 0.021
positive regulation of lipid biosynthetic process GO:0046889 18 0.021
response to radiation GO:0009314 165 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
heart contraction GO:0060047 93 0.021
positive regulation of cell development GO:0010720 237 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
macromolecule catabolic process GO:0009057 281 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
cell type specific apoptotic process GO:0097285 268 0.020
positive regulation of t cell activation GO:0050870 101 0.020
forebrain development GO:0030900 302 0.020
regulation of neuron differentiation GO:0045664 281 0.020
mitochondrion organization GO:0007005 134 0.020
cellular response to extracellular stimulus GO:0031668 81 0.020
spermatogenesis GO:0007283 284 0.019
sensory perception GO:0007600 245 0.019
blood circulation GO:0008015 195 0.019
regulation of cell projection organization GO:0031344 206 0.019
blood vessel morphogenesis GO:0048514 285 0.019
positive regulation of protein kinase activity GO:0045860 144 0.019
endocytosis GO:0006897 168 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
nucleotide transmembrane transport GO:1901679 2 0.019
camera type eye development GO:0043010 266 0.019
small molecule catabolic process GO:0044282 71 0.019
aromatic compound catabolic process GO:0019439 286 0.019
germ cell development GO:0007281 185 0.019
monocarboxylic acid metabolic process GO:0032787 191 0.019
placenta development GO:0001890 140 0.019
cytoplasmic transport GO:0016482 234 0.019
cellular response to carbohydrate stimulus GO:0071322 50 0.019
striated muscle tissue development GO:0014706 293 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
urogenital system development GO:0001655 261 0.018
regulation of t cell activation GO:0050863 170 0.018
microtubule based process GO:0007017 236 0.018
response to insulin GO:0032868 100 0.018
kidney development GO:0001822 213 0.018
cardiac chamber morphogenesis GO:0003206 93 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
protein targeting GO:0006605 143 0.018
cellular response to insulin stimulus GO:0032869 78 0.018
protein methylation GO:0006479 81 0.018
response to light stimulus GO:0009416 135 0.018
intracellular protein transport GO:0006886 204 0.018
peptidyl tyrosine modification GO:0018212 145 0.018
cerebral cortex development GO:0021987 86 0.018
organ growth GO:0035265 117 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
muscle cell differentiation GO:0042692 261 0.017
regulation of protein localization GO:0032880 231 0.017
sphingolipid metabolic process GO:0006665 45 0.017
positive regulation of kinase activity GO:0033674 155 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
tissue homeostasis GO:0001894 115 0.017
response to steroid hormone GO:0048545 56 0.017
zymogen activation GO:0031638 41 0.017
hair follicle development GO:0001942 85 0.017
positive regulation of cholesterol biosynthetic process GO:0045542 3 0.017
organophosphate catabolic process GO:0046434 232 0.016
regulation of hormone secretion GO:0046883 88 0.016
negative regulation of response to wounding GO:1903035 77 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
cellular response to starvation GO:0009267 57 0.016
regulation of blood circulation GO:1903522 93 0.016
fatty acid metabolic process GO:0006631 121 0.016
rhythmic process GO:0048511 174 0.016
homeostasis of number of cells GO:0048872 210 0.016
lymphocyte proliferation GO:0046651 164 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
cofactor biosynthetic process GO:0051188 41 0.016
ossification GO:0001503 216 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
hindbrain development GO:0030902 128 0.016
circulatory system process GO:0003013 197 0.016
embryonic placenta development GO:0001892 98 0.016
response to inorganic substance GO:0010035 96 0.016
cellular response to peptide GO:1901653 92 0.016
regulation of anatomical structure size GO:0090066 178 0.016
cation transport GO:0006812 399 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
t cell activation GO:0042110 289 0.015
myeloid cell differentiation GO:0030099 233 0.015
regulation of cytoskeleton organization GO:0051493 122 0.015
cellular response to sterol GO:0036315 2 0.015
acetyl coa metabolic process GO:0006084 8 0.015
immune effector process GO:0002252 321 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.015
cell adhesion GO:0007155 329 0.015
cellular ketone body metabolic process GO:0046950 3 0.015
heart morphogenesis GO:0003007 178 0.015
regulation of hydrolase activity GO:0051336 246 0.015
cellular response to organic cyclic compound GO:0071407 87 0.015
response to drug GO:0042493 75 0.015
negative regulation of hydrolase activity GO:0051346 71 0.015
cholesterol transport GO:0030301 38 0.015
cellular response to monosaccharide stimulus GO:0071326 47 0.015
regulation of system process GO:0044057 200 0.015
angiogenesis GO:0001525 201 0.015
multicellular organism growth GO:0035264 161 0.015
regulation of inflammatory response GO:0050727 147 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
nucleotide metabolic process GO:0009117 332 0.014
muscle tissue development GO:0060537 308 0.014
regulation of neuron projection development GO:0010975 169 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
sterol import GO:0035376 2 0.014
chemotaxis GO:0006935 247 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
mapk cascade GO:0000165 281 0.014
stress activated mapk cascade GO:0051403 80 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
fertilization GO:0009566 127 0.014
response to low density lipoprotein particle GO:0055098 2 0.014
androgen biosynthetic process GO:0006702 4 0.014
regulation of peptidase activity GO:0052547 96 0.014
regulation of membrane potential GO:0042391 192 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
regulation of actin cytoskeleton organization GO:0032956 84 0.014
organelle assembly GO:0070925 177 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
fatty acid biosynthetic process GO:0006633 41 0.013
triglyceride metabolic process GO:0006641 51 0.013
hexose catabolic process GO:0019320 3 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.013
protein localization to membrane GO:0072657 108 0.013
negative regulation of secretion by cell GO:1903531 54 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
spermatid differentiation GO:0048515 115 0.013
positive regulation of cell activation GO:0050867 158 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
negative regulation of protein processing GO:0010955 79 0.013
sensory system development GO:0048880 3 0.013
regulation of histone modification GO:0031056 56 0.013
response to temperature stimulus GO:0009266 55 0.013
leukocyte differentiation GO:0002521 342 0.013
rhodopsin mediated signaling pathway GO:0016056 4 0.013
cytokine production GO:0001816 319 0.013
leukocyte homeostasis GO:0001776 79 0.013
organelle fission GO:0048285 170 0.013
negative regulation of nervous system development GO:0051961 156 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.013
fatty acid transmembrane transport GO:1902001 1 0.013
regulation of protein transport GO:0051223 163 0.012
acetylcholine transport GO:0015870 2 0.012
hair cycle GO:0042633 90 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
carbohydrate metabolic process GO:0005975 230 0.012
regulation of cholesterol homeostasis GO:2000188 9 0.012
photoreceptor cell morphogenesis GO:0008594 3 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
pallium development GO:0021543 120 0.012
regulation of triglyceride biosynthetic process GO:0010866 10 0.012
negative regulation of inflammatory response GO:0050728 61 0.012
dicarboxylic acid transport GO:0006835 29 0.012
developmental maturation GO:0021700 193 0.012
locomotory behavior GO:0007626 195 0.012
purine nucleotide metabolic process GO:0006163 302 0.012
negative regulation of cell development GO:0010721 169 0.012
nuclear transport GO:0051169 139 0.012
cellular glucose homeostasis GO:0001678 52 0.012
learning or memory GO:0007611 148 0.012
positive regulation of insulin secretion GO:0032024 26 0.012
negative regulation of proteolysis GO:0045861 74 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
cardiac muscle tissue development GO:0048738 130 0.012
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.012
cation transmembrane transport GO:0098655 266 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
leukocyte proliferation GO:0070661 172 0.012
response to oxidative stress GO:0006979 123 0.012
positive regulation of cholesterol metabolic process GO:0090205 3 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
positive regulation of chromosome organization GO:2001252 33 0.012
molting cycle GO:0042303 90 0.012
regulation of ion transport GO:0043269 215 0.012
multicellular organismal homeostasis GO:0048871 164 0.011
plasma membrane organization GO:0007009 90 0.011
connective tissue development GO:0061448 179 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
peptidyl serine phosphorylation GO:0018105 74 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
actin cytoskeleton organization GO:0030036 220 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
regulation of protein maturation GO:1903317 96 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
notch signaling pathway GO:0007219 71 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
chromatin organization GO:0006325 206 0.011
mesenchyme development GO:0060485 152 0.011
labyrinthine layer development GO:0060711 49 0.011
regulation of protein processing GO:0070613 96 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
protein alkylation GO:0008213 81 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
dendrite development GO:0016358 115 0.011
detection of abiotic stimulus GO:0009582 60 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
cholesterol storage GO:0010878 4 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
positive regulation of growth GO:0045927 104 0.011
cellular response to hexose stimulus GO:0071331 47 0.011
organic acid biosynthetic process GO:0016053 86 0.011
cellular biogenic amine metabolic process GO:0006576 28 0.011
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.011
nucleoside metabolic process GO:0009116 246 0.011
response to growth factor GO:0070848 198 0.011
regulation of protein catabolic process GO:0042176 108 0.011
nucleoside catabolic process GO:0009164 206 0.011
regulation of cell motility GO:2000145 236 0.011
limb development GO:0060173 166 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.011
nucleotide catabolic process GO:0009166 217 0.011
nadph regeneration GO:0006740 2 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
regulation of cholesterol biosynthetic process GO:0045540 8 0.010
mitotic cell cycle process GO:1903047 159 0.010
appendage development GO:0048736 166 0.010
spermatid development GO:0007286 108 0.010
positive regulation of peptide secretion GO:0002793 33 0.010
localization within membrane GO:0051668 4 0.010
monocarboxylic acid transport GO:0015718 44 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
cellular response to glucose stimulus GO:0071333 45 0.010
cholesterol efflux GO:0033344 24 0.010
ear development GO:0043583 200 0.010
purine containing compound metabolic process GO:0072521 311 0.010
demethylation GO:0070988 23 0.010
neuron death GO:0070997 154 0.010
ribonucleoside metabolic process GO:0009119 245 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.010
regulation of endopeptidase activity GO:0052548 89 0.010
regulation of intracellular transport GO:0032386 159 0.010

Mvd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.644
inherited metabolic disorder DOID:655 0 0.340
lipid metabolism disorder DOID:3146 0 0.152
disease of cellular proliferation DOID:14566 0 0.017
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.011
gastrointestinal system cancer DOID:3119 0 0.010
intestinal cancer DOID:10155 0 0.010