Mus musculus

221 known processes

Myh6

myosin, heavy polypeptide 6, cardiac muscle, alpha

(Aliases: AA517445,alpha-MHC,Myhc-a,MGC118706,Myhca,A830009F23Rik)

Myh6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle system process GO:0003012 141 0.631
circulatory system process GO:0003013 197 0.579
muscle contraction GO:0006936 101 0.564
regulation of system process GO:0044057 200 0.477
cardiocyte differentiation GO:0035051 87 0.461
muscle cell development GO:0055001 133 0.446
cellular amino acid metabolic process GO:0006520 103 0.429
striated muscle contraction GO:0006941 45 0.419
cellular ketone metabolic process GO:0042180 84 0.402
regulation of muscle system process GO:0090257 80 0.367
Mouse
amine metabolic process GO:0009308 45 0.360
regulation of heart contraction GO:0008016 77 0.340
heart contraction GO:0060047 93 0.337
regulation of the force of heart contraction GO:0002026 17 0.336
cardiac muscle tissue development GO:0048738 130 0.335
regulation of muscle contraction GO:0006937 49 0.327
blood circulation GO:0008015 195 0.308
nucleobase containing small molecule metabolic process GO:0055086 352 0.306
regulation of cellular amine metabolic process GO:0033238 20 0.302
muscle adaptation GO:0043500 39 0.301
Mouse
urogenital system development GO:0001655 261 0.285
cellular amine metabolic process GO:0044106 44 0.280
striated muscle tissue development GO:0014706 293 0.269
purine containing compound metabolic process GO:0072521 311 0.269
organonitrogen compound catabolic process GO:1901565 264 0.263
regulation of cellular ketone metabolic process GO:0010565 66 0.262
regulation of blood circulation GO:1903522 93 0.252
heart morphogenesis GO:0003007 178 0.242
cardiac ventricle morphogenesis GO:0003208 50 0.241
actin filament based movement GO:0030048 23 0.228
sarcomere organization GO:0045214 24 0.226
cellular potassium ion transport GO:0071804 43 0.223
metal ion homeostasis GO:0055065 189 0.218
cellular chemical homeostasis GO:0055082 215 0.214
cation transport GO:0006812 399 0.210
cardiac chamber morphogenesis GO:0003206 93 0.206
nucleotide metabolic process GO:0009117 332 0.205
purine nucleotide metabolic process GO:0006163 302 0.201
muscle cell differentiation GO:0042692 261 0.201
cellular component assembly involved in morphogenesis GO:0010927 139 0.200
inorganic cation transmembrane transport GO:0098662 207 0.194
regulation of hormone levels GO:0010817 211 0.190
organelle assembly GO:0070925 177 0.186
heart process GO:0003015 94 0.178
ion transmembrane transport GO:0034220 361 0.176
cardiac muscle cell development GO:0055013 39 0.173
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.169
cell adhesion GO:0007155 329 0.169
ventricular cardiac myofibril assembly GO:0055005 3 0.165
cardiac muscle cell differentiation GO:0055007 69 0.162
mapk cascade GO:0000165 281 0.157
response to oxygen levels GO:0070482 62 0.151
muscle fiber development GO:0048747 76 0.141
negative regulation of molecular function GO:0044092 258 0.139
cardiac cell development GO:0055006 41 0.137
ventricular cardiac muscle cell action potential GO:0086005 4 0.136
cardiac myofibril assembly GO:0055003 12 0.133
nucleotide catabolic process GO:0009166 217 0.133
smoothened signaling pathway GO:0007224 105 0.131
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.131
glycosyl compound metabolic process GO:1901657 246 0.128
kidney epithelium development GO:0072073 121 0.127
nucleoside triphosphate metabolic process GO:0009141 230 0.127
purine nucleoside metabolic process GO:0042278 241 0.126
ribonucleoside metabolic process GO:0009119 245 0.124
muscle cell fate specification GO:0042694 1 0.123
ribose phosphate metabolic process GO:0019693 291 0.123
nucleoside phosphate metabolic process GO:0006753 338 0.122
regulation of secretion GO:0051046 274 0.122
transmembrane transport GO:0055085 412 0.119
regulation of muscle adaptation GO:0043502 31 0.118
Mouse
ossification GO:0001503 216 0.118
actin mediated cell contraction GO:0070252 15 0.116
cardiac muscle contraction GO:0060048 32 0.116
potassium ion transmembrane transport GO:0071805 43 0.114
cardiac muscle cell contraction GO:0086003 7 0.114
cellular homeostasis GO:0019725 240 0.113
monocarboxylic acid metabolic process GO:0032787 191 0.112
purine ribonucleoside metabolic process GO:0046128 241 0.112
regulation of cell projection organization GO:0031344 206 0.110
cation homeostasis GO:0055080 212 0.109
actin cytoskeleton organization GO:0030036 220 0.108
negative regulation of protein metabolic process GO:0051248 282 0.106
cardiac muscle tissue morphogenesis GO:0055008 44 0.106
skeletal muscle thin filament assembly GO:0030240 2 0.105
Zebrafish
positive regulation of nervous system development GO:0051962 221 0.099
response to organic cyclic compound GO:0014070 198 0.098
heterocycle catabolic process GO:0046700 280 0.096
ribonucleoside catabolic process GO:0042454 206 0.096
organic cyclic compound catabolic process GO:1901361 295 0.094
response to reactive oxygen species GO:0000302 56 0.094
ras protein signal transduction GO:0007265 77 0.093
striated muscle cell development GO:0055002 125 0.093
negative regulation of phosphorus metabolic process GO:0010563 184 0.090
organonitrogen compound biosynthetic process GO:1901566 192 0.089
cardiac chamber development GO:0003205 108 0.088
cellular response to lipid GO:0071396 145 0.088
cellular response to organic cyclic compound GO:0071407 87 0.088
glycosyl compound catabolic process GO:1901658 206 0.088
purine ribonucleotide metabolic process GO:0009150 290 0.086
purine nucleoside triphosphate metabolic process GO:0009144 226 0.086
rho protein signal transduction GO:0007266 32 0.085
aromatic compound catabolic process GO:0019439 286 0.085
regulation of cellular amino acid metabolic process GO:0006521 5 0.084
respiratory system development GO:0060541 190 0.081
Fly
regulation of hydrolase activity GO:0051336 246 0.080
regulation of ion transmembrane transport GO:0034765 119 0.080
response to hypoxia GO:0001666 58 0.079
innate immune response GO:0045087 157 0.079
potassium ion transport GO:0006813 52 0.079
regulation of cell cycle GO:0051726 281 0.078
feeding behavior GO:0007631 62 0.078
Worm
regulation of ion transport GO:0043269 215 0.078
positive regulation of mapk cascade GO:0043410 170 0.078
inositol lipid mediated signaling GO:0048017 41 0.077
Worm
regulation of purine nucleotide catabolic process GO:0033121 122 0.077
negative regulation of phosphate metabolic process GO:0045936 184 0.077
nucleoside metabolic process GO:0009116 246 0.077
carbohydrate derivative biosynthetic process GO:1901137 183 0.076
positive regulation of protein modification process GO:0031401 299 0.075
peptidyl amino acid modification GO:0018193 336 0.075
lipid biosynthetic process GO:0008610 179 0.074
vascular process in circulatory system GO:0003018 62 0.074
small molecule biosynthetic process GO:0044283 132 0.073
locomotory behavior GO:0007626 195 0.072
Worm
regulation of neuron apoptotic process GO:0043523 122 0.071
regulation of heart rate GO:0002027 36 0.069
purine ribonucleotide catabolic process GO:0009154 208 0.067
organic hydroxy compound metabolic process GO:1901615 203 0.067
cardiac muscle fiber development GO:0048739 4 0.067
sensory perception GO:0007600 245 0.067
neuron death GO:0070997 154 0.067
response to peptide GO:1901652 136 0.066
renal system development GO:0072001 225 0.066
regulation of tube size GO:0035150 57 0.066
regulation of cellular response to stress GO:0080135 159 0.066
regulation of ureteric bud formation GO:0072106 3 0.065
camera type eye development GO:0043010 266 0.063
myofibril assembly GO:0030239 34 0.063
muscle tissue development GO:0060537 308 0.062
purine nucleotide catabolic process GO:0006195 211 0.062
lung development GO:0030324 164 0.062
hepaticobiliary system development GO:0061008 67 0.062
carbohydrate derivative catabolic process GO:1901136 231 0.062
negative regulation of cell proliferation GO:0008285 296 0.061
regulation of kinase activity GO:0043549 249 0.061
regulation of organelle organization GO:0033043 289 0.061
Mouse
axonogenesis GO:0007409 274 0.061
skeletal myofibril assembly GO:0014866 4 0.060
Zebrafish Mouse Worm Fly
renal tubule morphogenesis GO:0061333 72 0.060
regulation of sarcomere organization GO:0060297 4 0.060
Mouse
response to lipopolysaccharide GO:0032496 128 0.060
gas homeostasis GO:0033483 3 0.060
regulation of purine nucleotide metabolic process GO:1900542 169 0.060
hematopoietic progenitor cell differentiation GO:0002244 143 0.059
carbohydrate metabolic process GO:0005975 230 0.059
male gamete generation GO:0048232 285 0.059
nucleoside phosphate catabolic process GO:1901292 222 0.059
cytokine production GO:0001816 319 0.059
purine containing compound catabolic process GO:0072523 213 0.058
kidney development GO:0001822 213 0.057
regulation of cellular catabolic process GO:0031329 242 0.057
response to molecule of bacterial origin GO:0002237 143 0.057
eating behavior GO:0042755 15 0.057
Worm
cellular metal ion homeostasis GO:0006875 151 0.056
cellular response to acid chemical GO:0071229 68 0.056
cell type specific apoptotic process GO:0097285 268 0.056
regulation of transferase activity GO:0051338 263 0.056
regulation of anatomical structure size GO:0090066 178 0.056
cellular modified amino acid metabolic process GO:0006575 63 0.055
regulation of ras gtpase activity GO:0032318 88 0.055
cellular calcium ion homeostasis GO:0006874 119 0.055
glucose homeostasis GO:0042593 128 0.055
spermatogenesis GO:0007283 284 0.055
regulation of lipid metabolic process GO:0019216 118 0.055
regulation of striated muscle contraction GO:0006942 25 0.054
regulation of mapk cascade GO:0043408 248 0.054
regulation of neuron death GO:1901214 134 0.054
muscle tissue morphogenesis GO:0060415 53 0.054
cation transmembrane transport GO:0098655 266 0.054
regulation of blood pressure GO:0008217 93 0.053
protein secretion GO:0009306 111 0.053
stem cell development GO:0048864 219 0.053
regulation of neurotransmitter levels GO:0001505 87 0.052
peptide transport GO:0015833 133 0.052
insulin secretion GO:0030073 89 0.052
response to monosaccharide GO:0034284 67 0.052
multicellular organismal response to stress GO:0033555 62 0.051
endocytosis GO:0006897 168 0.051
Worm
negative regulation of phosphorylation GO:0042326 166 0.050
regulation of secretion by cell GO:1903530 249 0.050
multicellular organismal signaling GO:0035637 91 0.049
response to decreased oxygen levels GO:0036293 59 0.049
mitotic cell cycle GO:0000278 195 0.049
action potential GO:0001508 78 0.049
cellular response to molecule of bacterial origin GO:0071219 83 0.049
negative regulation of cellular protein metabolic process GO:0032269 247 0.048
septum primum development GO:0003284 4 0.048
actomyosin structure organization GO:0031032 56 0.048
regulation of nucleotide metabolic process GO:0006140 169 0.048
cellular response to hormone stimulus GO:0032870 150 0.047
negative regulation of protein phosphorylation GO:0001933 126 0.046
negative regulation of cellular component organization GO:0051129 194 0.046
response to peptide hormone GO:0043434 127 0.046
response to inorganic substance GO:0010035 96 0.046
cellular response to monosaccharide stimulus GO:0071326 47 0.046
glucose metabolic process GO:0006006 92 0.046
organophosphate catabolic process GO:0046434 232 0.045
tissue homeostasis GO:0001894 115 0.045
regulation of homeostatic process GO:0032844 182 0.045
regulation of feeding behavior GO:0060259 3 0.044
skeletal muscle fiber development GO:0048741 58 0.044
Mouse
neurotransmitter transport GO:0006836 76 0.043
nitrogen compound transport GO:0071705 271 0.043
regulation of membrane potential GO:0042391 192 0.043
negative regulation of cellular amine metabolic process GO:0033239 1 0.043
tendon cell differentiation GO:0035990 4 0.042
nephron morphogenesis GO:0072028 69 0.042
morphogenesis of embryonic epithelium GO:0016331 159 0.041
myeloid cell differentiation GO:0030099 233 0.041
cellular response to biotic stimulus GO:0071216 92 0.041
negative regulation of nervous system development GO:0051961 156 0.041
regulation of establishment of protein localization GO:0070201 181 0.041
negative regulation of lipid metabolic process GO:0045833 30 0.041
striated muscle cell proliferation GO:0014855 39 0.041
ribonucleoside triphosphate metabolic process GO:0009199 220 0.040
myosin filament organization GO:0031033 3 0.040
Zebrafish Mouse Worm Fly
regulation of cell activation GO:0050865 289 0.040
developmental maturation GO:0021700 193 0.040
stem cell differentiation GO:0048863 268 0.040
nucleoside monophosphate metabolic process GO:0009123 85 0.040
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
regulation of binding GO:0051098 111 0.039
cardiac conduction GO:0061337 17 0.039
sequestering of calcium ion GO:0051208 18 0.039
cellular divalent inorganic cation homeostasis GO:0072503 127 0.039
nephron development GO:0072006 109 0.039
myosin filament assembly GO:0031034 2 0.039
Zebrafish Mouse Worm Fly
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.039
multi multicellular organism process GO:0044706 109 0.039
Worm
vasoconstriction GO:0042310 27 0.038
nephron tubule development GO:0072080 84 0.038
leukocyte activation involved in immune response GO:0002366 126 0.038
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.038
cellular lipid metabolic process GO:0044255 323 0.038
nucleoside catabolic process GO:0009164 206 0.038
amide transport GO:0042886 138 0.037
oxidation reduction process GO:0055114 342 0.037
regulation of peptidyl serine phosphorylation GO:0033135 39 0.037
embryonic heart tube development GO:0035050 65 0.037
liver development GO:0001889 66 0.037
purine ribonucleoside catabolic process GO:0046130 205 0.037
negative regulation of cell motility GO:2000146 61 0.036
regulation of cell cycle process GO:0010564 160 0.036
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.036
inorganic ion transmembrane transport GO:0098660 234 0.036
ribonucleoside monophosphate metabolic process GO:0009161 80 0.035
ribonucleoside triphosphate catabolic process GO:0009203 199 0.035
establishment of blood nerve barrier GO:0008065 3 0.035
mesonephric tubule morphogenesis GO:0072171 63 0.035
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.035
positive regulation of neuron differentiation GO:0045666 141 0.035
positive regulation of growth GO:0045927 104 0.035
rhythmic process GO:0048511 174 0.035
positive regulation of kinase activity GO:0033674 155 0.035
sodium ion transmembrane transport GO:0035725 49 0.034
regulation of cellular response to growth factor stimulus GO:0090287 82 0.034
anion transport GO:0006820 177 0.034
chromatin organization GO:0006325 206 0.034
regulation of skeletal muscle contraction GO:0014819 3 0.034
mechanoreceptor differentiation GO:0042490 67 0.034
ribonucleotide metabolic process GO:0009259 291 0.034
negative regulation of intracellular signal transduction GO:1902532 167 0.034
skeletal muscle organ development GO:0060538 163 0.034
Mouse
chromatin modification GO:0016568 187 0.034
regulation of cell division GO:0051302 76 0.034
neuron apoptotic process GO:0051402 142 0.034
organic acid biosynthetic process GO:0016053 86 0.034
peptide secretion GO:0002790 114 0.033
catecholamine metabolic process GO:0006584 30 0.033
positive regulation of protein phosphorylation GO:0001934 242 0.033
immune effector process GO:0002252 321 0.033
hindbrain development GO:0030902 128 0.033
aortic valve morphogenesis GO:0003180 4 0.033
regulation of gtp catabolic process GO:0033124 113 0.032
cellular carbohydrate metabolic process GO:0044262 119 0.032
t cell activation GO:0042110 289 0.032
cellular nitrogen compound catabolic process GO:0044270 280 0.032
regulation of synaptic plasticity GO:0048167 87 0.032
carbohydrate transport GO:0008643 62 0.032
regulation of cardiac muscle contraction GO:0055117 21 0.032
mitral valve development GO:0003174 4 0.032
response to growth factor GO:0070848 198 0.032
purine nucleoside catabolic process GO:0006152 205 0.032
guanosine containing compound catabolic process GO:1901069 144 0.032
cytokine secretion GO:0050663 72 0.032
extracellular structure organization GO:0043062 148 0.031
regulation of actin filament based process GO:0032970 99 0.031
Mouse
synaptic transmission GO:0007268 329 0.031
striated muscle adaptation GO:0014888 26 0.031
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.031
regulation of neuron projection development GO:0010975 169 0.031
bmp signaling pathway GO:0030509 93 0.031
hormone metabolic process GO:0042445 86 0.031
response to oxidative stress GO:0006979 123 0.031
mesonephros development GO:0001823 97 0.031
organophosphate biosynthetic process GO:0090407 122 0.031
peptidyl serine phosphorylation GO:0018105 74 0.031
embryonic epithelial tube formation GO:0001838 130 0.031
endodermal cell fate specification GO:0001714 4 0.031
steroid metabolic process GO:0008202 119 0.030
response to estrogen GO:0043627 24 0.030
membrane depolarization during sa node cell action potential GO:0086046 2 0.030
regulation of protein secretion GO:0050708 82 0.030
negative regulation of neuron apoptotic process GO:0043524 92 0.030
endomembrane system organization GO:0010256 147 0.030
positive regulation of ureteric bud formation GO:0072107 3 0.030
divalent inorganic cation homeostasis GO:0072507 138 0.030
skeletal muscle cell differentiation GO:0035914 66 0.030
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.029
apoptotic signaling pathway GO:0097190 306 0.029
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.029
divalent inorganic cation transport GO:0072511 178 0.029
ventricular cardiac muscle tissue development GO:0003229 38 0.029
neurotransmitter uptake GO:0001504 14 0.029
anatomical structure homeostasis GO:0060249 145 0.029
learning or memory GO:0007611 148 0.029
positive regulation of potassium ion transmembrane transport GO:1901381 3 0.029
cardiac ventricle development GO:0003231 83 0.029
positive regulation of potassium ion transport GO:0043268 3 0.029
organelle localization GO:0051640 179 0.029
blastocyst development GO:0001824 80 0.029
leukocyte differentiation GO:0002521 342 0.028
cardiac muscle hypertrophy in response to stress GO:0014898 10 0.028
sensory perception of mechanical stimulus GO:0050954 107 0.028
cellular response to growth factor stimulus GO:0071363 197 0.028
regulation of ion transmembrane transporter activity GO:0032412 54 0.028
response to activity GO:0014823 13 0.028
Mouse
epithelial tube morphogenesis GO:0060562 303 0.028
tissue migration GO:0090130 68 0.028
Fly
positive regulation of organ growth GO:0046622 29 0.028
respiratory tube development GO:0030323 167 0.028
myeloid leukocyte differentiation GO:0002573 119 0.028
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.028
monosaccharide metabolic process GO:0005996 106 0.028
negative regulation of protein modification process GO:0031400 163 0.027
regulation of protein localization GO:0032880 231 0.027
regulation of cell motility GO:2000145 236 0.027
renal tubule development GO:0061326 87 0.027
forebrain development GO:0030900 302 0.027
response to acid chemical GO:0001101 111 0.027
calcium ion homeostasis GO:0055074 127 0.027
regulation of cytoskeleton organization GO:0051493 122 0.027
Mouse
response to organonitrogen compound GO:0010243 246 0.027
response to vitamin a GO:0033189 1 0.027
stem cell proliferation GO:0072089 117 0.026
cognition GO:0050890 149 0.026
establishment or maintenance of cell polarity GO:0007163 86 0.026
muscle filament sliding GO:0030049 1 0.026
multicellular organismal homeostasis GO:0048871 164 0.026
positive regulation of cell cycle GO:0045787 92 0.026
gonad development GO:0008406 141 0.026
cellular response to carbohydrate stimulus GO:0071322 50 0.026
positive regulation of transferase activity GO:0051347 167 0.026
blood coagulation GO:0007596 76 0.026
response to steroid hormone GO:0048545 56 0.026
peptide hormone secretion GO:0030072 109 0.026
central nervous system maturation GO:0021626 6 0.026
cellular response to organonitrogen compound GO:0071417 145 0.026
protein maturation GO:0051604 176 0.026
angiogenesis GO:0001525 201 0.026
single organism cell adhesion GO:0098602 156 0.026
striated muscle myosin thick filament assembly GO:0071688 1 0.026
Zebrafish Mouse Worm Fly
microtubule cytoskeleton organization GO:0000226 157 0.026
regulation of blood vessel size GO:0050880 56 0.026
cytosolic calcium ion transport GO:0060401 48 0.026
covalent chromatin modification GO:0016569 163 0.026
regulation of transporter activity GO:0032409 57 0.025
smooth muscle contraction GO:0006939 44 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
erythrocyte differentiation GO:0030218 88 0.025
maintenance of location GO:0051235 89 0.025
histone modification GO:0016570 159 0.025
regulation of peptide secretion GO:0002791 77 0.025
regulation of rho gtpase activity GO:0032319 58 0.025
cellular response to glucose stimulus GO:0071333 45 0.025
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.025
response to drug GO:0042493 75 0.025
regulation of actin cytoskeleton organization GO:0032956 84 0.025
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.025
actin myosin filament sliding GO:0033275 1 0.025
cholesterol homeostasis GO:0042632 44 0.025
ribonucleoside monophosphate catabolic process GO:0009158 57 0.025
mesonephric tubule development GO:0072164 94 0.025
regulation of chromosome organization GO:0033044 83 0.025
response to metal ion GO:0010038 47 0.025
protein glycosylation GO:0006486 55 0.025
bone mineralization GO:0030282 54 0.025
actin filament bundle assembly GO:0051017 40 0.025
regulation of cell migration GO:0030334 219 0.025
macromolecule catabolic process GO:0009057 281 0.025
telencephalon development GO:0021537 186 0.025
morphogenesis of a branching structure GO:0001763 203 0.025
cell cell junction organization GO:0045216 72 0.025
skeletal system development GO:0001501 356 0.025
peptidyl tyrosine modification GO:0018212 145 0.024
regulation of endocytosis GO:0030100 69 0.024
embryonic placenta development GO:0001892 98 0.024
positive regulation of stem cell proliferation GO:2000648 59 0.024
phosphatidylinositol mediated signaling GO:0048015 41 0.024
development of primary sexual characteristics GO:0045137 143 0.024
multicellular organismal metabolic process GO:0044236 28 0.024
synapse organization GO:0050808 125 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
negative regulation of hormone biosynthetic process GO:0032353 4 0.024
lateral inhibition GO:0046331 1 0.024
ventricular cardiac muscle cell differentiation GO:0055012 17 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
negative regulation of neuron differentiation GO:0045665 101 0.024
tendon formation GO:0035992 4 0.024
cellular amino acid biosynthetic process GO:0008652 22 0.024
positive regulation of stress activated mapk cascade GO:0032874 48 0.024
nephron tubule morphogenesis GO:0072078 68 0.024
regulation of protein transport GO:0051223 163 0.023
mesonephric epithelium development GO:0072163 94 0.023
neural tube development GO:0021915 160 0.023
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.023
lung morphogenesis GO:0060425 50 0.023
negative regulation of secretion GO:0051048 61 0.023
neuromuscular process GO:0050905 99 0.023
cellular glucose homeostasis GO:0001678 52 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.023
regulation of hormone secretion GO:0046883 88 0.023
positive regulation of smooth muscle cell migration GO:0014911 4 0.023
regulation of cardiac muscle tissue development GO:0055024 31 0.023
organ regeneration GO:0031100 2 0.023
cellular response to cytokine stimulus GO:0071345 189 0.023
sinoatrial node development GO:0003163 4 0.023
regulation of transmembrane transport GO:0034762 128 0.023
nephron epithelium morphogenesis GO:0072088 68 0.023
sa node cell action potential GO:0086015 4 0.023
regulation of protein maturation GO:1903317 96 0.023
inner ear receptor cell differentiation GO:0060113 61 0.022
organelle fission GO:0048285 170 0.022
extracellular matrix organization GO:0030198 147 0.022
actin filament organization GO:0007015 113 0.022
Zebrafish Fly
positive regulation of hormone secretion GO:0046887 38 0.022
positive regulation of hydrolase activity GO:0051345 148 0.022
canonical wnt signaling pathway GO:0060070 130 0.022
regulation of erk1 and erk2 cascade GO:0070372 71 0.022
dna metabolic process GO:0006259 303 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
regulation of skeletal muscle fiber development GO:0048742 36 0.022
positive regulation of cell activation GO:0050867 158 0.022
cellular response to external stimulus GO:0071496 88 0.022
heart trabecula formation GO:0060347 14 0.022
neural precursor cell proliferation GO:0061351 121 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
regulation of atp catabolic process GO:1903289 9 0.022
reactive nitrogen species metabolic process GO:2001057 0 0.022
negative regulation of cell development GO:0010721 169 0.021
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 12 0.021
positive regulation of protein transport GO:0051222 93 0.021
positive regulation of fatty acid oxidation GO:0046321 4 0.021
lipid oxidation GO:0034440 29 0.021
regulation of transforming growth factor beta2 production GO:0032909 2 0.021
epithelium migration GO:0090132 63 0.021
Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.021
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.021
exogenous drug catabolic process GO:0042738 1 0.021
response to transforming growth factor beta GO:0071559 88 0.021
hexose metabolic process GO:0019318 98 0.021
positive regulation of interleukin 8 secretion GO:2000484 1 0.021
directional locomotion GO:0033058 3 0.021
multi organism behavior GO:0051705 62 0.021
Worm
purine nucleoside monophosphate catabolic process GO:0009128 58 0.021
mitochondrion organization GO:0007005 134 0.021
cell maturation GO:0048469 127 0.021
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.021
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.021
lipid homeostasis GO:0055088 63 0.021
leukocyte mediated immunity GO:0002443 174 0.020
platelet activation GO:0030168 40 0.020
learning GO:0007612 98 0.020

Myh6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.859
disease of anatomical entity DOID:7 0 0.859
musculoskeletal system disease DOID:17 0 0.859
myopathy DOID:423 0 0.741
heart disease DOID:114 0 0.741
cardiomyopathy DOID:0050700 0 0.741
intrinsic cardiomyopathy DOID:0060036 0 0.741
cardiovascular system disease DOID:1287 0 0.741
muscle tissue disease DOID:66 0 0.741
hypertrophic cardiomyopathy DOID:11984 0 0.248
dilated cardiomyopathy DOID:12930 0 0.106