Mus musculus

65 known processes

Naglu

alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)

Naglu biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lysosome organization GO:0007040 21 0.259
lytic vacuole organization GO:0080171 21 0.157
vacuole organization GO:0007033 38 0.128
sphingolipid metabolic process GO:0006665 45 0.111
sphingolipid catabolic process GO:0030149 7 0.105
carbohydrate metabolic process GO:0005975 230 0.100
carbohydrate derivative catabolic process GO:1901136 231 0.100
oxidation reduction process GO:0055114 342 0.077
cellular lipid metabolic process GO:0044255 323 0.059
ceramide metabolic process GO:0006672 31 0.059
membrane lipid metabolic process GO:0006643 53 0.057
organonitrogen compound catabolic process GO:1901565 264 0.056
glycolipid metabolic process GO:0006664 25 0.056
locomotory behavior GO:0007626 195 0.053
male gamete generation GO:0048232 285 0.045
lymphocyte mediated immunity GO:0002449 139 0.044
sensory perception GO:0007600 245 0.044
skeletal system development GO:0001501 356 0.044
cellular amide metabolic process GO:0043603 58 0.043
small molecule biosynthetic process GO:0044283 132 0.043
membrane lipid biosynthetic process GO:0046467 32 0.042
spermatogenesis GO:0007283 284 0.039
neuromuscular process GO:0050905 99 0.038
hexose metabolic process GO:0019318 98 0.038
monosaccharide metabolic process GO:0005996 106 0.037
cellular protein catabolic process GO:0044257 155 0.037
immune effector process GO:0002252 321 0.037
transmission of nerve impulse GO:0019226 76 0.037
response to molecule of bacterial origin GO:0002237 143 0.036
glycolipid catabolic process GO:0019377 5 0.036
cellular amino acid metabolic process GO:0006520 103 0.036
alcohol metabolic process GO:0006066 116 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
vitamin metabolic process GO:0006766 23 0.033
transmembrane transport GO:0055085 412 0.033
regulation of membrane potential GO:0042391 192 0.032
nucleotide metabolic process GO:0009117 332 0.032
regulation of defense response GO:0031347 233 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.032
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
anatomical structure homeostasis GO:0060249 145 0.031
respiratory system development GO:0060541 190 0.031
regulation of secretion by cell GO:1903530 249 0.030
regulation of hydrolase activity GO:0051336 246 0.029
leukocyte mediated immunity GO:0002443 174 0.029
sulfur compound metabolic process GO:0006790 100 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
lipid biosynthetic process GO:0008610 179 0.028
cellular modified amino acid metabolic process GO:0006575 63 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
ceramide biosynthetic process GO:0046513 20 0.026
cellular response to organonitrogen compound GO:0071417 145 0.026
amine metabolic process GO:0009308 45 0.026
cation transmembrane transport GO:0098655 266 0.025
adaptive immune response GO:0002250 155 0.025
camera type eye development GO:0043010 266 0.025
peptide metabolic process GO:0006518 46 0.025
macromolecule catabolic process GO:0009057 281 0.025
monocarboxylic acid metabolic process GO:0032787 191 0.025
nitrogen compound transport GO:0071705 271 0.024
peptidyl amino acid modification GO:0018193 336 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.024
glycosphingolipid catabolic process GO:0046479 5 0.024
positive regulation of proteolysis GO:0045862 85 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
hindbrain development GO:0030902 128 0.024
regulation of cellular ketone metabolic process GO:0010565 66 0.024
regulation of vascular smooth muscle contraction GO:0003056 1 0.023
organelle assembly GO:0070925 177 0.023
multicellular organismal signaling GO:0035637 91 0.023
ion transmembrane transport GO:0034220 361 0.023
phospholipid transfer to membrane GO:0006649 2 0.023
nuclear division GO:0000280 158 0.023
lung development GO:0030324 164 0.023
response to organonitrogen compound GO:0010243 246 0.023
regulation of peptidase activity GO:0052547 96 0.022
multicellular organismal homeostasis GO:0048871 164 0.022
neuromuscular process controlling balance GO:0050885 59 0.022
oligosaccharide catabolic process GO:0009313 2 0.022
respiratory tube development GO:0030323 167 0.022
neuronal action potential GO:0019228 54 0.022
modification dependent protein catabolic process GO:0019941 133 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
purine containing compound metabolic process GO:0072521 311 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
regulation of proteolysis GO:0030162 164 0.021
organic anion transport GO:0015711 137 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.021
cytokine production GO:0001816 319 0.021
anion transmembrane transport GO:0098656 71 0.021
lateral inhibition GO:0046331 1 0.021
response to acid chemical GO:0001101 111 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
maintenance of location GO:0051235 89 0.020
learning or memory GO:0007611 148 0.020
ubiquitin dependent protein catabolic process GO:0006511 129 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
cellular amine metabolic process GO:0044106 44 0.019
cell type specific apoptotic process GO:0097285 268 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
oligosaccharide metabolic process GO:0009311 11 0.019
tissue homeostasis GO:0001894 115 0.019
cytoplasmic transport GO:0016482 234 0.019
reactive nitrogen species metabolic process GO:2001057 0 0.019
striated muscle tissue development GO:0014706 293 0.019
sensory perception of sound GO:0007605 97 0.019
membrane organization GO:0061024 245 0.019
positive regulation of protein modification process GO:0031401 299 0.019
glycosyl compound catabolic process GO:1901658 206 0.018
apoptotic signaling pathway GO:0097190 306 0.018
organic acid transport GO:0015849 101 0.018
single fertilization GO:0007338 82 0.018
regulation of system process GO:0044057 200 0.018
amino acid transport GO:0006865 61 0.018
regulation of cytokine production GO:0001817 266 0.018
dephosphorylation GO:0016311 129 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
epidermis development GO:0008544 187 0.018
water soluble vitamin metabolic process GO:0006767 10 0.018
cation homeostasis GO:0055080 212 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
multicellular organismal macromolecule catabolic process GO:0044266 1 0.017
sphingosine metabolic process GO:0006670 4 0.017
blood vessel morphogenesis GO:0048514 285 0.017
regulation of interleukin 1 alpha production GO:0032650 4 0.017
gland development GO:0048732 330 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
regulation of cell migration GO:0030334 219 0.017
inflammatory response GO:0006954 244 0.017
dna recombination GO:0006310 92 0.017
epithelial cell proliferation GO:0050673 174 0.017
glycosylation GO:0070085 62 0.017
myelination GO:0042552 74 0.017
cation transport GO:0006812 399 0.017
membrane lipid catabolic process GO:0046466 8 0.017
dna metabolic process GO:0006259 303 0.017
glycoprotein metabolic process GO:0009100 116 0.016
ear development GO:0043583 200 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
forebrain development GO:0030900 302 0.016
nucleoside catabolic process GO:0009164 206 0.016
cognition GO:0050890 149 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
positive regulation of immune effector process GO:0002699 107 0.016
renal system development GO:0072001 225 0.016
metal ion homeostasis GO:0055065 189 0.016
regulation of cell cycle GO:0051726 281 0.016
response to organic cyclic compound GO:0014070 198 0.016
chemotaxis GO:0006935 247 0.016
leukocyte mediated cytotoxicity GO:0001909 62 0.016
heterocycle catabolic process GO:0046700 280 0.016
stem cell differentiation GO:0048863 268 0.016
fertilization GO:0009566 127 0.016
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.016
axonogenesis GO:0007409 274 0.016
somatotropin secreting cell development GO:0060133 2 0.016
macromolecule glycosylation GO:0043413 55 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
n acetylglucosamine metabolic process GO:0006044 3 0.015
organophosphate catabolic process GO:0046434 232 0.015
lipid catabolic process GO:0016042 69 0.015
kidney development GO:0001822 213 0.015
carboxylic acid transport GO:0046942 100 0.015
heart morphogenesis GO:0003007 178 0.015
glycosylceramide catabolic process GO:0046477 2 0.015
intracellular protein transport GO:0006886 204 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
protein catabolic process GO:0030163 221 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
negative regulation of cytokine production GO:0001818 84 0.015
regionalization GO:0003002 337 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
atp catabolic process GO:0006200 55 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
neural tube development GO:0021915 160 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
response to lipopolysaccharide GO:0032496 128 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.014
negative regulation of nervous system development GO:0051961 156 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
regulation of organelle organization GO:0033043 289 0.014
anion transport GO:0006820 177 0.014
muscle tissue development GO:0060537 308 0.014
cellular ketone metabolic process GO:0042180 84 0.014
cofactor transport GO:0051181 4 0.014
glycerolipid metabolic process GO:0046486 122 0.014
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
glycosylceramide metabolic process GO:0006677 4 0.014
organelle localization GO:0051640 179 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
regulation of protein maturation GO:1903317 96 0.014
neurotransmitter transport GO:0006836 76 0.014
protein secretion GO:0009306 111 0.014
regulation of protein localization GO:0032880 231 0.014
negative regulation of immune system process GO:0002683 209 0.014
response to light stimulus GO:0009416 135 0.014
skin development GO:0043588 220 0.014
fat soluble vitamin biosynthetic process GO:0042362 4 0.014
aromatic compound catabolic process GO:0019439 286 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
alanine transport GO:0032328 4 0.013
lipid localization GO:0010876 126 0.013
stem cell development GO:0048864 219 0.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.013
extracellular structure organization GO:0043062 148 0.013
positive regulation of peptidase activity GO:0010952 49 0.013
synaptic transmission GO:0007268 329 0.013
action potential GO:0001508 78 0.013
positive regulation of macroautophagy GO:0016239 3 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
establishment of vesicle localization GO:0051650 81 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
regulation of lymphocyte mediated immunity GO:0002706 84 0.013
cellular response to lipid GO:0071396 145 0.013
nucleotide catabolic process GO:0009166 217 0.013
homeostasis of number of cells GO:0048872 210 0.013
negative regulation of dna replication GO:0008156 4 0.013
t cell activation GO:0042110 289 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
innate immune response GO:0045087 157 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
phagolysosome assembly GO:0001845 3 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling GO:0003027 1 0.013
lipid transport GO:0006869 98 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
sensory perception of light stimulus GO:0050953 54 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
interleukin 8 production GO:0032637 4 0.012
cell killing GO:0001906 67 0.012
axon ensheathment GO:0008366 76 0.012
defense response to other organism GO:0098542 197 0.012
positive regulation of cell motility GO:2000147 116 0.012
lymphocyte proliferation GO:0046651 164 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
endocytosis GO:0006897 168 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
regulation of anatomical structure size GO:0090066 178 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
regulation of transferase activity GO:0051338 263 0.012
positive regulation of cell activation GO:0050867 158 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
epithelial cell development GO:0002064 159 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
spermatid differentiation GO:0048515 115 0.012
cellular homeostasis GO:0019725 240 0.012
nucleotide sugar metabolic process GO:0009225 4 0.012
bone remodeling GO:0046849 53 0.012
regulation of adaptive immune response GO:0002819 90 0.012
t cell proliferation GO:0042098 120 0.012
angiogenesis GO:0001525 201 0.012
cell adhesion GO:0007155 329 0.012
gliogenesis GO:0042063 141 0.012
ensheathment of neurons GO:0007272 76 0.012
urogenital system development GO:0001655 261 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
positive regulation of adaptive immune response GO:0002821 61 0.012
segmentation GO:0035282 93 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
protein hydroxylation GO:0018126 4 0.011
germ cell development GO:0007281 185 0.011
sphingolipid biosynthetic process GO:0030148 26 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
cellular protein complex assembly GO:0043623 116 0.011
regulation of t cell mediated cytotoxicity GO:0001914 18 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
leukocyte proliferation GO:0070661 172 0.011
t cell mediated cytotoxicity GO:0001913 26 0.011
purine nucleotide metabolic process GO:0006163 302 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
bone development GO:0060348 120 0.011
muscle cell differentiation GO:0042692 261 0.011
liposaccharide metabolic process GO:1903509 27 0.011
multicellular organismal protein catabolic process GO:0044254 1 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
protein glycosylation GO:0006486 55 0.011
negative regulation of protein modification process GO:0031400 163 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.011
nuclear transport GO:0051169 139 0.011
positive regulation of cholesterol metabolic process GO:0090205 3 0.011
fucosylation GO:0036065 9 0.011
regulation of cell motility GO:2000145 236 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
regulation of intracellular transport GO:0032386 159 0.011
regulation of multi organism process GO:0043900 111 0.011
smoothened signaling pathway GO:0007224 105 0.011
beta amyloid clearance GO:0097242 2 0.011
mechanoreceptor differentiation GO:0042490 67 0.011
regulation of cell activation GO:0050865 289 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
cell cell recognition GO:0009988 44 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010
neuron projection guidance GO:0097485 141 0.010
leukocyte homeostasis GO:0001776 79 0.010
purine ribonucleotide metabolic process GO:0009150 290 0.010
lymphocyte homeostasis GO:0002260 64 0.010
membrane tubulation GO:0097320 4 0.010
regulation of leukocyte mediated immunity GO:0002703 104 0.010
muscle system process GO:0003012 141 0.010
positive regulation of cytokine production GO:0001819 174 0.010
positive regulation of interleukin 1 alpha production GO:0032730 4 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
positive regulation of cell death GO:0010942 224 0.010
telencephalon development GO:0021537 186 0.010
neuron projection extension GO:1990138 64 0.010
regulation of cysteine type endopeptidase activity GO:2000116 65 0.010
purine containing compound catabolic process GO:0072523 213 0.010
immunoglobulin production GO:0002377 73 0.010
atp metabolic process GO:0046034 75 0.010
ribose phosphate metabolic process GO:0019693 291 0.010

Naglu disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 0 0.531
disease of metabolism DOID:0014667 0 0.531
lysosomal storage disease DOID:3211 0 0.146
lipid storage disease DOID:9455 0 0.146
nervous system disease DOID:863 0 0.119
disease of anatomical entity DOID:7 0 0.119
central nervous system disease DOID:331 0 0.114
cerebral degeneration DOID:1443 0 0.042
brain disease DOID:936 0 0.042
sensory system disease DOID:0050155 0 0.039
sphingolipidosis DOID:1927 0 0.027
connective tissue disease DOID:65 0 0.023
musculoskeletal system disease DOID:17 0 0.023
neurodegenerative disease DOID:1289 0 0.021
immune system disease DOID:2914 0 0.014
bone disease DOID:0080001 0 0.012
mucopolysaccharidosis DOID:12798 0 0.011
eye disease DOID:5614 0 0.011
eye and adnexa disease DOID:1492 0 0.011
retinal disease DOID:5679 0 0.011
dementia DOID:1307 0 0.010
disease of mental health DOID:150 0 0.010
cognitive disorder DOID:1561 0 0.010