Mus musculus

115 known processes

Nbn

nibrin

(Aliases: Nbs1)

Nbn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 207 0.986
negative regulation of dna replication GO:0008156 4 0.949
telomere capping GO:0016233 4 0.919
negative regulation of cell cycle phase transition GO:1901988 48 0.884
dna repair GO:0006281 107 0.872
Human
negative regulation of cell cycle GO:0045786 123 0.861
response to ionizing radiation GO:0010212 42 0.853
regulation of cell cycle GO:0051726 281 0.838
protein autophosphorylation GO:0046777 61 0.824
Human
negative regulation of mitotic cell cycle GO:0045930 58 0.819
dna integrity checkpoint GO:0031570 28 0.780
dna damage checkpoint GO:0000077 26 0.767
intrinsic apoptotic signaling pathway GO:0097193 132 0.659
mitotic g2 dna damage checkpoint GO:0007095 8 0.653
double strand break repair GO:0006302 48 0.634
Human
regulation of mitotic cell cycle GO:0007346 126 0.619
intra s dna damage checkpoint GO:0031573 4 0.596
cell cycle checkpoint GO:0000075 47 0.596
negative regulation of cell proliferation GO:0008285 296 0.572
dna metabolic process GO:0006259 303 0.570
mitotic cell cycle GO:0000278 195 0.538
postreplication repair GO:0006301 5 0.524
non recombinational repair GO:0000726 10 0.499
response to radiation GO:0009314 165 0.488
regulation of cell cycle phase transition GO:1901987 77 0.485
cellular ketone metabolic process GO:0042180 84 0.444
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.436
negative regulation of protein metabolic process GO:0051248 282 0.422
double strand break repair via nonhomologous end joining GO:0006303 10 0.394
cellular macromolecule catabolic process GO:0044265 206 0.366
regulation of mitotic cell cycle phase transition GO:1901990 73 0.355
negative regulation of cellular protein metabolic process GO:0032269 247 0.351
regulation of cellular ketone metabolic process GO:0010565 66 0.351
cellular response to gamma radiation GO:0071480 4 0.332
organic cyclic compound catabolic process GO:1901361 295 0.330
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.323
meiotic cell cycle process GO:1903046 77 0.322
peptidyl amino acid modification GO:0018193 336 0.321
cell type specific apoptotic process GO:0097285 268 0.321
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.321
signal transduction by p53 class mediator GO:0072331 51 0.302
meiotic cell cycle GO:0051321 122 0.301
regulation of cellular response to stress GO:0080135 159 0.299
regulation of cellular amine metabolic process GO:0033238 20 0.298
synapsis GO:0007129 34 0.294
response to growth factor GO:0070848 198 0.290
regulation of cell cycle process GO:0010564 160 0.290
regulation of transferase activity GO:0051338 263 0.286
Human
negative regulation of phosphorylation GO:0042326 166 0.281
dna catabolic process exonucleolytic GO:0000738 3 0.278
dna endoreduplication GO:0042023 4 0.277
histone modification GO:0016570 159 0.276
regulation of cellular catabolic process GO:0031329 242 0.265
negative regulation of protein modification process GO:0031400 163 0.263
negative regulation of cell cycle process GO:0010948 69 0.262
anatomical structure homeostasis GO:0060249 145 0.261
Human
regulation of response to dna damage stimulus GO:2001020 34 0.258
homeostasis of number of cells GO:0048872 210 0.257
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.246
cellular amino acid metabolic process GO:0006520 103 0.242
cell cycle arrest GO:0007050 37 0.238
chromatin modification GO:0016568 187 0.232
mitotic g1 dna damage checkpoint GO:0031571 4 0.229
peptidyl lysine modification GO:0018205 77 0.228
neuron apoptotic process GO:0051402 142 0.215
positive regulation of cell death GO:0010942 224 0.209
negative regulation of cell activation GO:0050866 111 0.209
meiosis i GO:0007127 60 0.208
heterocycle catabolic process GO:0046700 280 0.204
Human
g1 s transition of mitotic cell cycle GO:0000082 57 0.198
dna catabolic process GO:0006308 19 0.197
amine metabolic process GO:0009308 45 0.195
somatic diversification of immune receptors GO:0002200 53 0.194
negative regulation of cellular amine metabolic process GO:0033239 1 0.191
response to x ray GO:0010165 11 0.189
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.186
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.182
positive regulation of cell cycle GO:0045787 92 0.181
cellular response to ionizing radiation GO:0071479 11 0.180
male meiosis i GO:0007141 16 0.180
neuron death GO:0070997 154 0.175
regulation of kinase activity GO:0043549 249 0.171
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.171
telomere maintenance GO:0000723 19 0.171
Human
adaptive immune response GO:0002250 155 0.170
t cell activation GO:0042110 289 0.166
regulation of lipid metabolic process GO:0019216 118 0.163
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.160
dna replication GO:0006260 52 0.158
regulation of cell cycle g1 s phase transition GO:1902806 35 0.153
stem cell differentiation GO:0048863 268 0.150
aromatic compound catabolic process GO:0019439 286 0.149
Human
recombinational repair GO:0000725 21 0.147
multicellular organismal homeostasis GO:0048871 164 0.146
cellular amine metabolic process GO:0044106 44 0.145
production of molecular mediator of immune response GO:0002440 103 0.145
cellular response to growth factor stimulus GO:0071363 197 0.144
negative regulation of dna dependent dna replication GO:2000104 1 0.143
response to light stimulus GO:0009416 135 0.136
regulation of protein catabolic process GO:0042176 108 0.132
positive regulation of cellular amine metabolic process GO:0033240 5 0.130
regulation of cellular amino acid metabolic process GO:0006521 5 0.128
response to nutrient levels GO:0031667 109 0.128
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.127
double strand break repair via homologous recombination GO:0000724 21 0.126
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.126
protein acylation GO:0043543 64 0.122
regulation of neuron apoptotic process GO:0043523 122 0.122
histone h4 k16 acetylation GO:0043984 3 0.119
regulation of neuron death GO:1901214 134 0.116
cell aging GO:0007569 35 0.116
reciprocal dna recombination GO:0035825 16 0.112
macromolecule catabolic process GO:0009057 281 0.110
negative regulation of phosphate metabolic process GO:0045936 184 0.110
somatic cell dna recombination GO:0016444 51 0.109
lipid biosynthetic process GO:0008610 179 0.109
reactive oxygen species metabolic process GO:0072593 84 0.108
apoptotic signaling pathway GO:0097190 306 0.107
protein modification by small protein conjugation or removal GO:0070647 207 0.107
somite development GO:0061053 81 0.107
blood vessel morphogenesis GO:0048514 285 0.106
base excision repair GO:0006284 9 0.102
dna dependent dna replication GO:0006261 24 0.101
cell fate commitment GO:0045165 210 0.101
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.100
gland development GO:0048732 330 0.098
negative regulation of protein processing GO:0010955 79 0.098
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.098
regulation of cellular response to growth factor stimulus GO:0090287 82 0.097
negative regulation of intracellular signal transduction GO:1902532 167 0.093
oocyte differentiation GO:0009994 35 0.093
protein localization to organelle GO:0033365 185 0.093
positive regulation of apoptotic process GO:0043065 217 0.092
positive regulation of protein phosphorylation GO:0001934 242 0.092
Human
internal protein amino acid acetylation GO:0006475 42 0.091
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.091
regulation of defense response GO:0031347 233 0.090
positive regulation of protein modification process GO:0031401 299 0.090
Human
nucleobase containing small molecule metabolic process GO:0055086 352 0.090
Human
ubiquitin dependent protein catabolic process GO:0006511 129 0.090
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.088
negative regulation of phosphorus metabolic process GO:0010563 184 0.088
purine ribonucleotide metabolic process GO:0009150 290 0.088
Human
lipid localization GO:0010876 126 0.088
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.088
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 2 0.087
maintenance of location GO:0051235 89 0.086
regulation of apoptotic signaling pathway GO:2001233 197 0.086
immune effector process GO:0002252 321 0.084
dna recombination GO:0006310 92 0.083
lymphocyte differentiation GO:0030098 242 0.083
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.082
nuclear division GO:0000280 158 0.082
regulation of dna endoreduplication GO:0032875 3 0.082
peptidyl serine modification GO:0018209 83 0.080
negative regulation of kinase activity GO:0033673 81 0.080
digestive tract morphogenesis GO:0048546 147 0.079
cell cycle g1 s phase transition GO:0044843 57 0.079
leukocyte differentiation GO:0002521 342 0.078
g2 dna damage checkpoint GO:0031572 8 0.078
regulation of dna replication GO:0006275 17 0.077
positive regulation of programmed cell death GO:0043068 218 0.076
regulation of protein maturation GO:1903317 96 0.076
chromosome organization involved in meiosis GO:0070192 39 0.076
histone acetylation GO:0016573 41 0.075
regulation of cell activation GO:0050865 289 0.075
methylation GO:0032259 134 0.074
microtubule cytoskeleton organization GO:0000226 157 0.074
germ cell development GO:0007281 185 0.072
protein maturation GO:0051604 176 0.072
regulation of protein kinase activity GO:0045859 232 0.072
b cell activation GO:0042113 161 0.071
negative regulation of lymphocyte activation GO:0051250 91 0.071
ribonucleoside catabolic process GO:0042454 206 0.071
Human
protein processing GO:0016485 163 0.070
oocyte development GO:0048599 33 0.070
positive regulation of protein autophosphorylation GO:0031954 4 0.070
Human
angiogenesis GO:0001525 201 0.070
modification dependent protein catabolic process GO:0019941 133 0.069
protein catabolic process GO:0030163 221 0.069
signal transduction involved in dna damage checkpoint GO:0072422 3 0.068
positive regulation of neuron apoptotic process GO:0043525 25 0.068
epithelial cell proliferation GO:0050673 174 0.067
positive regulation of histone h3 k4 methylation GO:0051571 5 0.067
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.067
regulation of protein autophosphorylation GO:0031952 8 0.065
Human
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.065
regulation of fatty acid biosynthetic process GO:0042304 12 0.064
negative regulation of apoptotic signaling pathway GO:2001234 104 0.063
mitotic cell cycle process GO:1903047 159 0.063
regulation of reactive oxygen species metabolic process GO:2000377 40 0.063
regulation of vasculature development GO:1901342 88 0.063
negative regulation of protein phosphorylation GO:0001933 126 0.062
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.062
leukocyte proliferation GO:0070661 172 0.062
renal system development GO:0072001 225 0.061
covalent chromatin modification GO:0016569 163 0.061
developmental maturation GO:0021700 193 0.061
glycerophospholipid biosynthetic process GO:0046474 32 0.060
mapk cascade GO:0000165 281 0.060
organelle fission GO:0048285 170 0.060
regulation of cell division GO:0051302 76 0.060
mitotic cell cycle checkpoint GO:0007093 31 0.059
positive regulation of protein acetylation GO:1901985 9 0.059
meiotic nuclear division GO:0007126 115 0.058
modification dependent macromolecule catabolic process GO:0043632 133 0.058
positive regulation of mesoderm development GO:2000382 2 0.058
positive regulation of mitotic cell cycle GO:0045931 41 0.057
chemotaxis GO:0006935 247 0.057
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.057
macromolecule methylation GO:0043414 120 0.057
ribonucleotide metabolic process GO:0009259 291 0.056
Human
protein modification by small protein conjugation GO:0032446 187 0.056
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.056
glycosyl compound catabolic process GO:1901658 206 0.055
Human
stress activated protein kinase signaling cascade GO:0031098 81 0.055
b cell activation involved in immune response GO:0002312 50 0.054
glycerolipid biosynthetic process GO:0045017 50 0.054
regulation of b cell activation GO:0050864 81 0.054
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 18 0.054
extrinsic apoptotic signaling pathway GO:0097191 126 0.054
leukocyte activation involved in immune response GO:0002366 126 0.054
hematopoietic progenitor cell differentiation GO:0002244 143 0.053
v d j recombination GO:0033151 14 0.053
regulation of histone h4 acetylation GO:0090239 3 0.053
chromosome segregation GO:0007059 48 0.052
microtubule based process GO:0007017 236 0.052
positive regulation of transferase activity GO:0051347 167 0.051
Human
negative regulation of neuron death GO:1901215 98 0.051
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.051
regulation of metaphase anaphase transition of cell cycle GO:1902099 9 0.051
negative regulation of cell cycle g1 s phase transition GO:1902807 18 0.051
reciprocal meiotic recombination GO:0007131 16 0.050
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.050
purine nucleoside triphosphate metabolic process GO:0009144 226 0.049
Human
phosphatidylinositol metabolic process GO:0046488 45 0.049
negative regulation of cellular catabolic process GO:0031330 47 0.049
response to transforming growth factor beta GO:0071559 88 0.049
regulation of mapk cascade GO:0043408 248 0.048
regulation of organelle organization GO:0033043 289 0.048
regulation of histone h3 k4 methylation GO:0051569 12 0.048
blastocyst growth GO:0001832 23 0.048
proteasomal protein catabolic process GO:0010498 98 0.047
regulation of epithelial cell proliferation GO:0050678 141 0.047
response to organonitrogen compound GO:0010243 246 0.046
regulation of proteolysis GO:0030162 164 0.046
meiotic chromosome segregation GO:0045132 19 0.046
protein ubiquitination GO:0016567 171 0.046
negative regulation of transferase activity GO:0051348 85 0.045
negative regulation of immune system process GO:0002683 209 0.045
histone h4 acetylation GO:0043967 10 0.044
response to organic cyclic compound GO:0014070 198 0.044
regionalization GO:0003002 337 0.044
positive regulation of kinase activity GO:0033674 155 0.044
Human
regulation of lymphocyte activation GO:0051249 240 0.044
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.043
histone lysine methylation GO:0034968 50 0.042
striated muscle tissue development GO:0014706 293 0.042
cell cycle switching GO:0060184 1 0.042
histone mrna metabolic process GO:0008334 3 0.042
ribonucleoside monophosphate metabolic process GO:0009161 80 0.042
Human
organophosphate biosynthetic process GO:0090407 122 0.041
chromosome separation GO:0051304 14 0.041
positive regulation of angiogenesis GO:0045766 46 0.041
erythrocyte differentiation GO:0030218 88 0.041
negative regulation of protein catabolic process GO:0042177 36 0.041
cellular nitrogen compound catabolic process GO:0044270 280 0.041
Human
regulation of transcription during meiosis GO:0051037 1 0.040
response to extracellular stimulus GO:0009991 127 0.040
regulation of cell cycle g2 m phase transition GO:1902749 10 0.039
regulation of meiotic cell cycle GO:0051445 34 0.039
negative regulation of neuron apoptotic process GO:0043524 92 0.039
positive regulation of hydrolase activity GO:0051345 148 0.039
positive regulation of histone acetylation GO:0035066 8 0.039
dna biosynthetic process GO:0071897 22 0.038
negative regulation of mapk cascade GO:0043409 65 0.038
phospholipid metabolic process GO:0006644 87 0.037
somitogenesis GO:0001756 69 0.037
positive regulation of cell cycle phase transition GO:1901989 17 0.037
phosphatidylinositol biosynthetic process GO:0006661 15 0.037
gastrulation GO:0007369 116 0.037
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.037
positive regulation of protein ubiquitination GO:0031398 27 0.037
sister chromatid segregation GO:0000819 20 0.037
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.036
isotype switching GO:0045190 36 0.036
digestive tract development GO:0048565 190 0.036
digestive system development GO:0055123 200 0.036
cellular protein catabolic process GO:0044257 155 0.036
regulation of fatty acid metabolic process GO:0019217 28 0.036
replicative senescence GO:0090399 2 0.035
cell division GO:0051301 120 0.035
cellular protein complex assembly GO:0043623 116 0.035
myeloid cell homeostasis GO:0002262 114 0.035
glycerophospholipid metabolic process GO:0006650 71 0.035
purine nucleotide metabolic process GO:0006163 302 0.035
Human
regulation of sister chromatid segregation GO:0033045 13 0.035
internal peptidyl lysine acetylation GO:0018393 42 0.035
signal transduction in response to dna damage GO:0042770 21 0.034
positive regulation of cell development GO:0010720 237 0.034
regulation of cellular component biogenesis GO:0044087 181 0.034
neuron projection guidance GO:0097485 141 0.034
negative regulation of molecular function GO:0044092 258 0.034
cell growth GO:0016049 130 0.034
response to oxidative stress GO:0006979 123 0.034
sister chromatid cohesion GO:0007062 12 0.034
stem cell development GO:0048864 219 0.034
intracellular protein transport GO:0006886 204 0.034
hematopoietic stem cell differentiation GO:0060218 8 0.034
peptidyl serine phosphorylation GO:0018105 74 0.034
cohesin localization to chromatin GO:0071921 1 0.033
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.033
kidney development GO:0001822 213 0.032
protein targeting GO:0006605 143 0.032
regulation of histone methylation GO:0031060 30 0.032
muscle cell differentiation GO:0042692 261 0.031
negative regulation of epithelial cell proliferation GO:0050680 64 0.031
cellular response to organonitrogen compound GO:0071417 145 0.031
negative regulation of fatty acid biosynthetic process GO:0045717 7 0.031
mitotic sister chromatid separation GO:0051306 9 0.031
lipid storage GO:0019915 36 0.031
negative regulation of protein maturation GO:1903318 79 0.031
regulation of leukocyte proliferation GO:0070663 121 0.030
locomotory behavior GO:0007626 195 0.030
somatic diversification of immunoglobulins GO:0016445 43 0.030
regulation of hydrolase activity GO:0051336 246 0.030
negative regulation of growth GO:0045926 99 0.030
mitochondrion organization GO:0007005 134 0.030
regulation of protein ubiquitination GO:0031396 52 0.030
female gamete generation GO:0007292 74 0.030
cellular lipid metabolic process GO:0044255 323 0.030
histone h3 k4 methylation GO:0051568 23 0.030
urogenital system development GO:0001655 261 0.030
glycosyl compound metabolic process GO:1901657 246 0.030
Human
ras protein signal transduction GO:0007265 77 0.030
mitotic cell cycle arrest GO:0071850 4 0.029
cellular response to cytokine stimulus GO:0071345 189 0.029
regulation of angiogenesis GO:0045765 81 0.029
regulation of lipid biosynthetic process GO:0046890 54 0.028
inflammatory response GO:0006954 244 0.028
negative regulation of nik nf kappab signaling GO:1901223 2 0.028
cell maturation GO:0048469 127 0.028
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.028
regulation of mitosis GO:0007088 29 0.028
cytoplasmic transport GO:0016482 234 0.028
purine containing compound metabolic process GO:0072521 311 0.028
Human
embryonic organ morphogenesis GO:0048562 276 0.027
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.027
peptidyl lysine acetylation GO:0018394 45 0.027
cellular senescence GO:0090398 11 0.027
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.027
nucleotide excision repair GO:0006289 13 0.027
regulation of leukocyte differentiation GO:1902105 159 0.027
response to starvation GO:0042594 65 0.027
response to inorganic substance GO:0010035 96 0.027
central nervous system neuron differentiation GO:0021953 162 0.027
regulation of cytoplasmic transport GO:1903649 112 0.027
positive regulation of cellular catabolic process GO:0031331 148 0.027
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.026
centrosome cycle GO:0007098 23 0.026
skeletal system development GO:0001501 356 0.026
photoreceptor cell maintenance GO:0045494 19 0.026
nuclear transport GO:0051169 139 0.026
cellular response to inorganic substance GO:0071241 37 0.025
chromatin organization GO:0006325 206 0.025
phosphatidylinositol 3 phosphate biosynthetic process GO:0036092 6 0.025
regulation of innate immune response GO:0045088 91 0.025
regulation of microtubule polymerization GO:0031113 7 0.025
regulation of chromosome organization GO:0033044 83 0.025
cytokine production GO:0001816 319 0.025
cellular homeostasis GO:0019725 240 0.025
blastocyst development GO:0001824 80 0.025
cellular response to extracellular stimulus GO:0031668 81 0.024
response to reactive oxygen species GO:0000302 56 0.024
attachment of spindle microtubules to kinetochore GO:0008608 4 0.024
muscle tissue development GO:0060537 308 0.024
purine nucleoside catabolic process GO:0006152 205 0.024
Human
regulation of protein processing GO:0070613 96 0.024
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.023
t cell differentiation in thymus GO:0033077 77 0.023
positive regulation of cell cycle process GO:0090068 61 0.023
development of primary sexual characteristics GO:0045137 143 0.023
positive regulation of cell activation GO:0050867 158 0.023
segmentation GO:0035282 93 0.023
immunoglobulin mediated immune response GO:0016064 69 0.023
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.023
signal transduction involved in cell cycle checkpoint GO:0072395 3 0.023
negative regulation of defense response GO:0031348 77 0.023
regulation of neuron differentiation GO:0045664 281 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
Human
fatty acid biosynthetic process GO:0006633 41 0.022
dendrite development GO:0016358 115 0.022
positive regulation of mapk cascade GO:0043410 170 0.022
regulation of histone acetylation GO:0035065 19 0.022
multi multicellular organism process GO:0044706 109 0.022
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.022
positive regulation of protein catabolic process GO:0045732 60 0.022
positive regulation of histone modification GO:0031058 28 0.022
regulation of autophagy GO:0010506 30 0.021
nucleocytoplasmic transport GO:0006913 139 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
muscle cell proliferation GO:0033002 52 0.021
negative regulation of fibroblast migration GO:0010764 2 0.021
regulation of b cell proliferation GO:0030888 39 0.021
body morphogenesis GO:0010171 45 0.021
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 11 0.021
intracellular signal transduction involved in g1 dna damage checkpoint GO:1902400 3 0.021
b cell proliferation GO:0042100 53 0.021
mitotic sister chromatid segregation GO:0000070 14 0.021
gene silencing GO:0016458 38 0.021
regulation of cellular protein catabolic process GO:1903362 61 0.021
establishment of protein localization to organelle GO:0072594 118 0.020
skeletal muscle cell differentiation GO:0035914 66 0.020
negative regulation of cell cycle arrest GO:0071157 1 0.020
lymphocyte proliferation GO:0046651 164 0.020
oocyte maturation GO:0001556 18 0.020
positive regulation of meiotic cell cycle GO:0051446 15 0.020
regulation of stem cell differentiation GO:2000736 50 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
regulation of intracellular transport GO:0032386 159 0.020
muscle contraction GO:0006936 101 0.020
protein localization to nucleus GO:0034504 121 0.020
translesion synthesis GO:0019985 1 0.020
negative regulation of mammary gland epithelial cell proliferation GO:0033600 3 0.020
negative regulation of map kinase activity GO:0043407 34 0.019
immunoglobulin production GO:0002377 73 0.019
positive regulation of histone methylation GO:0031062 16 0.019
regulation of body fluid levels GO:0050878 162 0.019
regulation of erk1 and erk2 cascade GO:0070372 71 0.019
pallium development GO:0021543 120 0.019
membrane organization GO:0061024 245 0.019
cerebellum development GO:0021549 77 0.019
axonogenesis GO:0007409 274 0.019
positive regulation of growth GO:0045927 104 0.018
small molecule biosynthetic process GO:0044283 132 0.018
purine containing compound biosynthetic process GO:0072522 70 0.018
erk1 and erk2 cascade GO:0070371 77 0.018
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.018
genetic imprinting GO:0071514 27 0.018
respiratory system development GO:0060541 190 0.018
regulation of endopeptidase activity GO:0052548 89 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
Human
negative regulation of b cell activation GO:0050869 27 0.018
skeletal muscle organ development GO:0060538 163 0.018
respiratory tube development GO:0030323 167 0.018
positive regulation of proteolysis GO:0045862 85 0.018
endocytosis GO:0006897 168 0.018
negative regulation of leukocyte differentiation GO:1902106 51 0.018
regulation of lymphocyte proliferation GO:0050670 117 0.018
positive regulation of peptidyl lysine acetylation GO:2000758 9 0.018
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 9 0.018
nucleotide metabolic process GO:0009117 332 0.018
Human
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.018
translation GO:0006412 93 0.017
positive regulation of neuron differentiation GO:0045666 141 0.017
positive regulation of lymphocyte activation GO:0051251 140 0.017
purine ribonucleotide biosynthetic process GO:0009152 59 0.017
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
Human
inner cell mass cell proliferation GO:0001833 15 0.017
regulation of binding GO:0051098 111 0.017
rhythmic process GO:0048511 174 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
cellular response to lipid GO:0071396 145 0.017
photoreceptor cell morphogenesis GO:0008594 3 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
retina homeostasis GO:0001895 23 0.017
single organism nuclear import GO:1902593 95 0.017
cation transport GO:0006812 399 0.017
positive regulation of cell adhesion GO:0045785 80 0.017
regulation of protein acetylation GO:1901983 22 0.017
circulatory system process GO:0003013 197 0.017
nucleoside monophosphate metabolic process GO:0009123 85 0.017
Human
centrosome duplication GO:0051298 16 0.017
response to tumor necrosis factor GO:0034612 26 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017

Nbn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
thoracic cancer DOID:5093 0 0.588
cancer DOID:162 0 0.588
Human
disease of cellular proliferation DOID:14566 0 0.588
Human
organ system cancer DOID:0050686 0 0.588
Human
breast cancer DOID:1612 0 0.213
immune system disease DOID:2914 0 0.181
Human
disease of anatomical entity DOID:7 0 0.181
Human
bone marrow disease DOID:4961 0 0.074
Human
hematopoietic system disease DOID:74 0 0.074
Human
endocrine gland cancer DOID:170 0 0.062
aplastic anemia DOID:12449 0 0.060
Human
anemia DOID:2355 0 0.060
Human
pancreatic cancer DOID:1793 0 0.055
urinary system cancer DOID:3996 0 0.050
congenital hypoplastic anemia DOID:1342 0 0.020
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
nervous system disease DOID:863 0 0.017
eye disease DOID:5614 0 0.017