|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.934
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.862
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
28 |
0.795
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.780
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
1 |
0.721
|
|
|
|
protein deacetylation
|
GO:0006476 |
32 |
0.705
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.698
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.690
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.663
|
|
|
|
histone methylation
|
GO:0016571 |
71 |
0.576
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.575
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.573
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.562
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.536
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.532
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.520
|
|
|
|
regulation of protein deacetylation
|
GO:0090311 |
17 |
0.503
|
|
|
|
regulation of chromatin silencing
|
GO:0031935 |
2 |
0.485
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.456
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.425
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.409
|
|
|
|
regulation of triglyceride metabolic process
|
GO:0090207 |
17 |
0.406
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.400
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.395
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.375
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.350
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.346
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.315
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.297
|
|
|
|
regulation of transcription during meiosis
|
GO:0051037 |
1 |
0.295
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.285
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.281
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.281
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.281
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.268
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.264
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.261
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.251
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
37 |
0.249
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.245
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.243
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.241
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.235
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.235
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.224
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.221
|
Human |
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.221
|
|
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
3 |
0.214
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.210
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.206
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.200
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.197
|
|
|
|
adipose tissue development
|
GO:0060612 |
25 |
0.195
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.190
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.189
|
|
|
|
chromatin silencing at rdna
|
GO:0000183 |
3 |
0.189
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.188
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.186
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.184
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.181
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.178
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.176
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.175
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.174
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.169
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.163
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.162
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.162
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.161
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.161
|
Human |
|
|
protein deacylation
|
GO:0035601 |
36 |
0.159
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.158
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.155
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.153
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.153
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.150
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.149
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.146
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.142
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.142
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.140
|
Human |
|
|
regionalization
|
GO:0003002 |
337 |
0.139
|
Zebrafish |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.138
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.137
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.136
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.136
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.136
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.133
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.133
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.131
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.130
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
13 |
0.130
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.129
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.126
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.126
|
|
|
|
maintenance of chromatin silencing
|
GO:0006344 |
2 |
0.125
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.123
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.120
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
29 |
0.115
|
|
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.114
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.114
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.112
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.107
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.107
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.106
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.105
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.105
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.104
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.104
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.103
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.103
|
|
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.103
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.101
|
|
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.100
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.097
|
|
|
|
memory
|
GO:0007613 |
58 |
0.096
|
|
|
|
dna modification
|
GO:0006304 |
50 |
0.096
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.095
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.095
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.094
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.093
|
|
|
|
dna templated transcriptional preinitiation complex assembly
|
GO:0070897 |
4 |
0.090
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.090
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.090
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.088
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.088
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.086
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.085
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.085
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.085
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.084
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
16 |
0.082
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.082
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.079
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.078
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.078
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.077
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
30 |
0.076
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.076
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.075
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.075
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.074
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.073
|
|
|
|
peptidyl lysine methylation
|
GO:0018022 |
29 |
0.072
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.071
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.070
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.070
|
Human |
|
|
limb development
|
GO:0060173 |
166 |
0.069
|
|
|
|
regulation of histone deacetylation
|
GO:0031063 |
12 |
0.069
|
|
|
|
chromatin mediated maintenance of transcription
|
GO:0048096 |
2 |
0.068
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.068
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.067
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.067
|
|
|
|
negative regulation of gene silencing
|
GO:0060969 |
2 |
0.066
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.066
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.066
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.066
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.065
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.064
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.064
|
|
|
|
regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045898 |
2 |
0.064
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.064
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
57 |
0.063
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.063
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.063
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.063
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.062
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.062
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.062
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.062
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.061
|
|
|
|
rna interference
|
GO:0016246 |
2 |
0.061
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.061
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.060
|
|
|
|
positive regulation of protein deacetylation
|
GO:0090312 |
9 |
0.060
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.060
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.059
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.059
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.059
|
|
|
|
negative regulation of transcription from rna polymerase i promoter
|
GO:0016479 |
2 |
0.058
|
|
|
|
thyroid hormone mediated signaling pathway
|
GO:0002154 |
3 |
0.058
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.058
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.058
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.057
|
|
|
|
regulation of androgen receptor signaling pathway
|
GO:0060765 |
3 |
0.057
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.056
|
|
|
|
cellular response to hexose stimulus
|
GO:0071331 |
47 |
0.056
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.056
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
28 |
0.056
|
|
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
66 |
0.055
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.055
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.055
|
|
|
|
mitotic sister chromatid cohesion
|
GO:0007064 |
1 |
0.054
|
|
|
|
type i pneumocyte differentiation
|
GO:0060509 |
7 |
0.054
|
Mouse |
|
|
negative regulation of mesenchymal cell proliferation
|
GO:0072201 |
3 |
0.054
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.052
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.052
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.051
|
|
|
|
adrenergic receptor signaling pathway
|
GO:0071875 |
13 |
0.051
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.050
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.050
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.050
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.050
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.049
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.049
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.049
|
|
|
|
regulation of histone methylation
|
GO:0031060 |
30 |
0.049
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.049
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.049
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.049
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.048
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.048
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.048
|
Human |
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.048
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.048
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.048
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.047
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.047
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.047
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.047
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.046
|
|
|
|
male meiosis
|
GO:0007140 |
37 |
0.046
|
|
|
|
regulation of locomotion involved in locomotory behavior
|
GO:0090325 |
1 |
0.046
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.046
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.045
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.045
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.045
|
|
|
|
face development
|
GO:0060324 |
38 |
0.045
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.044
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.044
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.044
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.044
|
|
|
|
histone h3 k4 methylation
|
GO:0051568 |
23 |
0.044
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.044
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.043
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.043
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.043
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.043
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.043
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.043
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.042
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.042
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.042
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.042
|
Mouse |
|
|
regulation of transcription from rna polymerase ii promoter by galactose
|
GO:0000431 |
1 |
0.041
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.041
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.041
|
|
|
|
positive regulation of insulin receptor signaling pathway
|
GO:0046628 |
4 |
0.041
|
|
|
|
cellular glucose homeostasis
|
GO:0001678 |
52 |
0.041
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.041
|
|
|
|
male meiosis i
|
GO:0007141 |
16 |
0.041
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
10 |
0.041
|
|
|
|
positive regulation of histone h3 k9 methylation
|
GO:0051574 |
4 |
0.041
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.041
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.041
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.040
|
|
|
|
stem cell fate specification
|
GO:0048866 |
3 |
0.040
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.040
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.040
|
Human |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.039
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.039
|
Mouse |
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.039
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.039
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
47 |
0.038
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.038
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.038
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.038
|
|
|
|
chromatin silencing
|
GO:0006342 |
15 |
0.038
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.038
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.038
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.037
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.037
|
|
|
|
positive regulation of mitotic sister chromatid separation
|
GO:1901970 |
2 |
0.037
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.037
|
|
|
|
carbon catabolite activation of transcription from rna polymerase ii promoter
|
GO:0000436 |
4 |
0.037
|
|
|
|
gene silencing by rna
|
GO:0031047 |
19 |
0.037
|
|
|
|
bone mineralization
|
GO:0030282 |
54 |
0.037
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.037
|
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.036
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.036
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.036
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.036
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.036
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.036
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.036
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.036
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.036
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.036
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.035
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.035
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.035
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.035
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.034
|
|
|
|
granulocyte differentiation
|
GO:0030851 |
17 |
0.034
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.034
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.034
|
|
|
|
histone h4 k16 acetylation
|
GO:0043984 |
3 |
0.034
|
|
|
|
lipid catabolic process
|
GO:0016042 |
69 |
0.034
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.034
|
Mouse |
|
|
regulation of planar cell polarity pathway involved in axis elongation
|
GO:2000040 |
3 |
0.034
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.034
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.034
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.034
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.034
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.033
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.033
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.033
|
|
|
|
response to estrogen
|
GO:0043627 |
24 |
0.033
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.032
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.032
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.032
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.032
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.032
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.032
|
|
|
|
regulation of adrenergic receptor signaling pathway
|
GO:0071877 |
4 |
0.032
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.032
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.032
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
60 |
0.031
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.031
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.031
|
|
|
|
acetylcholine transport
|
GO:0015870 |
2 |
0.031
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.031
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.031
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.031
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.031
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.030
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.030
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.030
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.030
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.030
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.030
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.030
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.030
|
|
|
|
carbon catabolite regulation of transcription from rna polymerase ii promoter
|
GO:0000429 |
4 |
0.029
|
|
|
|
golgi localization
|
GO:0051645 |
4 |
0.029
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.029
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.029
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.029
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.029
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.029
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.029
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.028
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.028
|
|
|
|
fat pad development
|
GO:0060613 |
6 |
0.028
|
|
|
|
regulation of mesenchymal cell proliferation involved in lung development
|
GO:2000790 |
2 |
0.028
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.028
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.028
|
|
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
18 |
0.028
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.028
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.028
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
15 |
0.028
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.028
|
Human |
|
|
embryonic camera type eye development
|
GO:0031076 |
36 |
0.028
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.028
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.028
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.027
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.027
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.027
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.027
|
Mouse |
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.027
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.027
|
|
|
|
triglyceride metabolic process
|
GO:0006641 |
51 |
0.027
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.027
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.027
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.027
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.026
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
23 |
0.026
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.026
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.026
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.026
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.026
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.026
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.025
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.025
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.025
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.025
|
Human |
|
|
spleen development
|
GO:0048536 |
39 |
0.025
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.025
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.025
|
|
|
|
cellular response to glucose stimulus
|
GO:0071333 |
45 |
0.025
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.025
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.025
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.025
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.024
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.024
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.024
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.024
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.024
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.024
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.024
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.024
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.023
|
Mouse |
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.023
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.023
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.023
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.023
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.023
|
|
|
|
dna alkylation
|
GO:0006305 |
43 |
0.023
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.023
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.023
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.023
|
|
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.023
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.023
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.023
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.023
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.023
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.022
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.022
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.022
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.022
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.022
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.022
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.022
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.022
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.022
|
|
|
|
retinoic acid receptor signaling pathway
|
GO:0048384 |
17 |
0.022
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.022
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.022
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
55 |
0.022
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.022
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.021
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.021
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.021
|
|
|
|
n terminal protein amino acid modification
|
GO:0031365 |
6 |
0.021
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.021
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.021
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.021
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.021
|
|
|
|
negative regulation of mesenchymal cell proliferation involved in lung development
|
GO:2000791 |
2 |
0.021
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.021
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
33 |
0.021
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.021
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.021
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.021
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.021
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.021
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.021
|
|
|
|
diencephalon development
|
GO:0021536 |
63 |
0.021
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.021
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.021
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.020
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
15 |
0.020
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.020
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.020
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
4 |
0.020
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.020
|
|
|
|
positive regulation of transcription by galactose
|
GO:0000411 |
1 |
0.020
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.020
|
|
|
|
ovulation
|
GO:0030728 |
15 |
0.020
|
|
|
|
response to dietary excess
|
GO:0002021 |
18 |
0.020
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.020
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.020
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.020
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.020
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.020
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.020
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.019
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.019
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.019
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.019
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.019
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.019
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.019
|
|
|
|
negative regulation of histone modification
|
GO:0031057 |
18 |
0.019
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.019
|
|
|
|
thyroid hormone metabolic process
|
GO:0042403 |
16 |
0.019
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.019
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.018
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.018
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
10 |
0.018
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.018
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.018
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.018
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.018
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.018
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.018
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.018
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.018
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.018
|
|
|
|
regulation of transcription from rna polymerase i promoter
|
GO:0006356 |
6 |
0.018
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.018
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.018
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.018
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.018
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.018
|
Human |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.018
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.018
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.018
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.018
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.018
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.018
|
|
|
|
histone h3 k4 trimethylation
|
GO:0080182 |
5 |
0.017
|
|
