|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.994
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.994
|
|
|
|
detection of fungus
|
GO:0016046 |
2 |
0.990
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.990
|
|
|
|
detection of yeast
|
GO:0001879 |
2 |
0.978
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.930
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.917
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.898
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.852
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.842
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.825
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.818
|
|
|
|
detection of other organism
|
GO:0098543 |
8 |
0.812
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.809
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.799
|
|
|
|
cellular response to molecule of fungal origin
|
GO:0071226 |
2 |
0.793
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.778
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.762
|
|
|
|
granzyme mediated apoptotic signaling pathway
|
GO:0008626 |
1 |
0.755
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.755
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.741
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.738
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.727
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.723
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.711
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.708
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.695
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.695
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.676
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.671
|
Mouse |
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.659
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.658
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.658
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.656
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.654
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.651
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.650
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.644
|
Mouse |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.644
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.633
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.632
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.628
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.613
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.607
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.589
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.583
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.581
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.580
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.561
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.559
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.540
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.518
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.511
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.503
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.496
|
|
|
|
detection of external biotic stimulus
|
GO:0098581 |
9 |
0.496
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.494
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.490
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.457
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.452
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.450
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.441
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.438
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.437
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.434
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.433
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.428
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.414
|
|
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.410
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.408
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.404
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.399
|
Mouse |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.396
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.394
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.390
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.388
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.384
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.380
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.375
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.374
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.368
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.356
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.355
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.350
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.344
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.340
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.339
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.339
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.338
|
Mouse |
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.335
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.335
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.329
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.324
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.317
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.313
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.310
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.309
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.305
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.305
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.304
|
Mouse |
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.291
|
|
|
|
neutrophil mediated killing of gram positive bacterium
|
GO:0070946 |
2 |
0.290
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.289
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.289
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.285
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.284
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.282
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.282
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.281
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.280
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.276
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.274
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.273
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.271
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.270
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.270
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.266
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.266
|
Mouse |
|
|
protein secretion
|
GO:0009306 |
111 |
0.265
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.263
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.258
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.258
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.255
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.252
|
|
|
|
response to yeast
|
GO:0001878 |
6 |
0.252
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.249
|
|
|
|
positive regulation of natural killer cell mediated cytotoxicity
|
GO:0045954 |
16 |
0.249
|
|
|
|
cellular response to drug
|
GO:0035690 |
15 |
0.249
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.248
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.246
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.245
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.240
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.239
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.238
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.236
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.235
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.232
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.231
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.228
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.227
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.224
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.223
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.221
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.221
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.220
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.220
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.218
|
|
|
|
detection of biotic stimulus
|
GO:0009595 |
10 |
0.216
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.215
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.214
|
|
|
|
regulation of angiotensin levels in blood
|
GO:0002002 |
4 |
0.214
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.212
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.211
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.211
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.206
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.203
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.200
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.199
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.198
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.197
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.196
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.191
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.190
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.190
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.190
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.189
|
Mouse |
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.189
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.189
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.183
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.181
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.177
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.177
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.173
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.173
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.172
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.172
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.170
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.168
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.168
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.166
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.166
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.165
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.165
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.165
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.164
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.164
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.162
|
|
|
|
regulation of thymocyte migration
|
GO:2000410 |
2 |
0.162
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.160
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.159
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.158
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.158
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.157
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.156
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.155
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.155
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.155
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.150
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.150
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.150
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.150
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.149
|
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.149
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.149
|
Mouse |
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.148
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.148
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.148
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.147
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.146
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.145
|
|
|
|
phagocytosis recognition
|
GO:0006910 |
12 |
0.144
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.142
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.141
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.137
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.136
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.136
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.133
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.133
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.133
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.133
|
|
|
|
defense response to fungus
|
GO:0050832 |
12 |
0.133
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.133
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.131
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.129
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.129
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.128
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.128
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.127
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.126
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.124
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.124
|
|
|
|
platelet morphogenesis
|
GO:0036344 |
13 |
0.123
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.123
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.122
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.121
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.121
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.120
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.119
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.119
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.118
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.118
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.117
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.115
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.115
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.115
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.115
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.113
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.113
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.112
|
|
|
|
positive regulation of t helper 2 cell cytokine production
|
GO:2000553 |
3 |
0.112
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.111
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.110
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.109
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.109
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.105
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.104
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.104
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.103
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.102
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.102
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.102
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.102
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.101
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.101
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.101
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.101
|
|
|
|
killing of cells of other organism
|
GO:0031640 |
13 |
0.101
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.100
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.099
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.099
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.098
|
|
|
|
regulation of angiotensin metabolic process
|
GO:0060177 |
4 |
0.098
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.098
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.098
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.098
|
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
18 |
0.098
|
|
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
19 |
0.098
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.096
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.095
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.094
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.093
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.093
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.093
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.092
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.091
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.091
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.091
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.090
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.090
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.089
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.088
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.088
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.087
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.087
|
|
|
|
killing by host of symbiont cells
|
GO:0051873 |
11 |
0.087
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.087
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
25 |
0.086
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.086
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.086
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.085
|
Mouse |
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.085
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.084
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.084
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.083
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.083
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.083
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.083
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.082
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.082
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.082
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.081
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.080
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.080
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.080
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.079
|
|
|
|
modulation of growth of symbiont involved in interaction with host
|
GO:0044144 |
19 |
0.079
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.079
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.078
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.077
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.077
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.077
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.077
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.077
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.077
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.076
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.076
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.076
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.076
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.076
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.076
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.076
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.074
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.074
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.074
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.074
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.074
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.074
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.074
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.073
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.073
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.073
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.072
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.072
|
|
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.072
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.072
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.072
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.071
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.071
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.071
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
23 |
0.071
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.071
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.071
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.070
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.070
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.070
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.069
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.069
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.069
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.069
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.068
|
|
|
|
platelet formation
|
GO:0030220 |
12 |
0.068
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.068
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.067
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.067
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.067
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.067
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.066
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.066
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.066
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.065
|
|
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.065
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.065
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.064
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.064
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.064
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.064
|
|
|
|
fc receptor mediated stimulatory signaling pathway
|
GO:0002431 |
4 |
0.063
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.063
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.063
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.063
|
|
|
|
positive regulation of nitric oxide biosynthetic process
|
GO:0045429 |
14 |
0.063
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.062
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.062
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.061
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.061
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.061
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
2 |
0.061
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.060
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.060
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.060
|
|
|
|
macrophage chemotaxis
|
GO:0048246 |
14 |
0.060
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.059
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.059
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.059
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.059
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.059
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.058
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.058
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.057
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.057
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.057
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.057
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.056
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.056
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.056
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.056
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.055
|
|
|
|
mammary gland duct morphogenesis
|
GO:0060603 |
38 |
0.055
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.055
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.055
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.054
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.054
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.054
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.053
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.053
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.053
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.053
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.053
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.053
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.052
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
18 |
0.052
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.051
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.051
|
|
|
|
regulation of hematopoietic stem cell migration
|
GO:2000471 |
1 |
0.051
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.051
|
|
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
10 |
0.050
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.050
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.050
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
25 |
0.050
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.050
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.050
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.050
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.050
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.049
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.049
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.049
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.048
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.048
|
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.048
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.048
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.048
|
|
|
|
regulation of antigen processing and presentation
|
GO:0002577 |
10 |
0.048
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.047
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.047
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.047
|
|
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
19 |
0.047
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.047
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.047
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.047
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.047
|
|
|
|
dendritic cell chemotaxis
|
GO:0002407 |
7 |
0.046
|
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.046
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.046
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
28 |
0.046
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.046
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.046
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.045
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
15 |
0.045
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.045
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.045
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.045
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.045
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.045
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.044
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.044
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.043
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.043
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.043
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.043
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.042
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.042
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.042
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.042
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.042
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.042
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.042
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.042
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.041
|
|
|
|
positive regulation of immune complex clearance by monocytes and macrophages
|
GO:0090265 |
2 |
0.041
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.041
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.041
|
|
|
|
negative regulation of myeloid cell apoptotic process
|
GO:0033033 |
11 |
0.041
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.041
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.041
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.040
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.040
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.040
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.040
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.040
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.040
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.040
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.039
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.039
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.039
|
|
|
|
dna endoreduplication
|
GO:0042023 |
4 |
0.039
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.039
|
|
